locus-tag	class	description
BBC0122_RS00005	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BBC0122_RS00010	COG0424	maF-like protein
BBC0122_RS00015	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBC0122_RS00020	COG0237	dephospho-CoA kinase activity
BBC0122_RS00025	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BBC0122_RS00030	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBC0122_RS00030	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BBC0122_RS00045	COG0137	argininosuccinate synthase activity
BBC0122_RS00055	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBC0122_RS00070	COG1250	3-hydroxyacyl-CoA dehydrogenase
BBC0122_RS00075	COG2096	Adenosyltransferase
BBC0122_RS00085	COG1671	Belongs to the UPF0178 family
BBC0122_RS00090	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBC0122_RS00105	COG0019	diaminopimelate decarboxylase activity
BBC0122_RS00125	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBC0122_RS00155	COG0667	Aldo Keto reductase
BBC0122_RS00165	COG2226	methyltransferase
BBC0122_RS00175	COG0745	RESPONSE REGULATOR receiver
BBC0122_RS00185	COG0825	malonyl-CoA metabolic process
BBC0122_RS00205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBC0122_RS00210	COG1686	Belongs to the peptidase S11 family
BBC0122_RS00215	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BBC0122_RS00220	COG0181	hydroxymethylbilane synthase activity
BBC0122_RS00225	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBC0122_RS00235	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBC0122_RS00240	COG1420	regulation of RNA biosynthetic process
BBC0122_RS00250	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BBC0122_RS00255	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBC0122_RS00265	COG3395	kinase activity
BBC0122_RS00270	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BBC0122_RS00275	COG1349	DNA-binding transcription factor activity
BBC0122_RS00280	COG0346	lactoylglutathione lyase activity
BBC0122_RS00290	COG1396	sequence-specific DNA binding
BBC0122_RS00290	COG3800	Transcriptional regulator
BBC0122_RS00300	COG0667	Aldo Keto reductase
BBC0122_RS00310	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BBC0122_RS00320	COG0697	spore germination
BBC0122_RS00325	COG0481	GTPase activity
BBC0122_RS00335	COG2171	N-acyltransferase activity
BBC0122_RS00355	COG0443	Heat shock 70 kDa protein
BBC0122_RS00360	COG0484	heat shock protein binding
BBC0122_RS00365	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBC0122_RS00375	COG1473	amidohydrolase
BBC0122_RS00380	COG1473	amidohydrolase
BBC0122_RS00390	COG1473	amidohydrolase
BBC0122_RS00395	COG1376	ErfK ybiS ycfS ynhG family protein
BBC0122_RS00405	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BBC0122_RS00410	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BBC0122_RS00420	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBC0122_RS00425	COG0531	amino acid
BBC0122_RS00435	COG1132	(ABC) transporter
BBC0122_RS00440	COG0604	alcohol dehydrogenase
BBC0122_RS00465	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BBC0122_RS00470	COG1072	(Pantothenic acid kinase))
BBC0122_RS00485	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BBC0122_RS00495	COG0131	Imidazoleglycerol-phosphate dehydratase
BBC0122_RS00500	COG0252	asparaginase activity
BBC0122_RS00505	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BBC0122_RS00510	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BBC0122_RS00515	COG2855	membrane
BBC0122_RS00520	COG0583	DNA-binding transcription factor activity
BBC0122_RS00540	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BBC0122_RS00550	COG0116	Belongs to the methyltransferase superfamily
BBC0122_RS00550	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BBC0122_RS00575	COG1137	ATPase activity
BBC0122_RS00585	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BBC0122_RS00590	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBC0122_RS00595	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBC0122_RS00640	COG0606	chelatase, subunit chli
BBC0122_RS00645	COG0729	surface antigen
BBC0122_RS00660	COG1216	Glycosyl transferase, family 2
BBC0122_RS00670	COG1216	Glycosyl transferase, family 2
BBC0122_RS00690	COG2205	protein histidine kinase activity
BBC0122_RS00695	COG0802	atpase or kinase
BBC0122_RS00700	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BBC0122_RS00705	COG2887	Belongs to the helicase family. UvrD subfamily
BBC0122_RS00710	COG1074	ATP-dependent DNA helicase activity
BBC0122_RS00720	COG1396	sequence-specific DNA binding
BBC0122_RS00725	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BBC0122_RS00770	COG1652	LysM domain
BBC0122_RS00785	COG0745	RESPONSE REGULATOR receiver
BBC0122_RS00790	COG2205	protein histidine kinase activity
BBC0122_RS00795	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBC0122_RS00800	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBC0122_RS00800	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBC0122_RS00805	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBC0122_RS00815	COG2860	membrane
BBC0122_RS00820	COG2130	NADP-dependent
BBC0122_RS00825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBC0122_RS00830	COG2326	polyphosphate kinase activity
BBC0122_RS00845	COG0101	tRNA pseudouridine synthase activity
BBC0122_RS00850	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BBC0122_RS00855	COG0242	peptide deformylase activity
BBC0122_RS00885	COG0697	spore germination
BBC0122_RS00930	COG0071	Belongs to the small heat shock protein (HSP20) family
BBC0122_RS00940	COG2169	Transcriptional regulator
BBC0122_RS00940	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BBC0122_RS00945	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BBC0122_RS00950	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BBC0122_RS00960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BBC0122_RS00965	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBC0122_RS00965	COG0072	phenylalanine-tRNA ligase activity
BBC0122_RS00990	COG0702	epimerase
BBC0122_RS01000	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BBC0122_RS01005	COG0159	tryptophan synthase activity
BBC0122_RS01010	COG0133	tryptophan synthase activity
BBC0122_RS01025	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBC0122_RS01035	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BBC0122_RS01040	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BBC0122_RS01045	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBC0122_RS01050	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BBC0122_RS01060	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BBC0122_RS01080	COG1121	(ABC) transporter
BBC0122_RS01085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBC0122_RS01090	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBC0122_RS01105	COG1376	ErfK ybiS ycfS ynhG family protein
BBC0122_RS01105	COG1388	LysM domain
BBC0122_RS01110	COG2832	Protein of unknown function (DUF454)
BBC0122_RS01125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBC0122_RS01140	COG0670	Belongs to the BI1 family
BBC0122_RS01145	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BBC0122_RS01150	COG4181	ATPase activity
BBC0122_RS01165	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BBC0122_RS01175	COG1643	Atp-dependent helicase
BBC0122_RS01180	COG0251	oxidation-reduction process
BBC0122_RS01200	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BBC0122_RS01205	COG3459	Glycosyltransferase 36 associated
BBC0122_RS01210	COG0280	phosphate acetyltransferase
BBC0122_RS01210	COG0281	malic enzyme
BBC0122_RS01215	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BBC0122_RS01220	COG0183	Belongs to the thiolase family
BBC0122_RS01225	COG0318	PFAM AMP-dependent synthetase and ligase
BBC0122_RS01230	COG0129	dihydroxy-acid dehydratase activity
BBC0122_RS01235	COG0778	Nitroreductase
BBC0122_RS01245	COG0863	Belongs to the N(4) N(6)-methyltransferase family
BBC0122_RS01265	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BBC0122_RS01270	COG0539	negative regulation of cytoplasmic translation
BBC0122_RS01275	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BBC0122_RS01300	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BBC0122_RS01320	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBC0122_RS01335	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBC0122_RS01350	COG0189	ligase activity
BBC0122_RS01360	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBC0122_RS01370	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBC0122_RS01375	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BBC0122_RS01380	COG4133	protoheme IX ABC transporter activity
BBC0122_RS01385	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BBC0122_RS01390	COG0268	Binds directly to 16S ribosomal RNA
BBC0122_RS01400	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BBC0122_RS01415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBC0122_RS01425	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BBC0122_RS01430	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BBC0122_RS01435	COG1845	cytochrome c oxidase, subunit III
BBC0122_RS01440	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BBC0122_RS01450	COG0783	Belongs to the Dps family
BBC0122_RS01455	COG1214	PFAM Peptidase M22, glycoprotease
BBC0122_RS01465	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBC0122_RS01475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BBC0122_RS01485	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BBC0122_RS01490	COG1396	sequence-specific DNA binding
BBC0122_RS01495	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BBC0122_RS01500	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BBC0122_RS01505	COG0779	Required for maturation of 30S ribosomal subunits
BBC0122_RS01510	COG0195	Participates in both transcription termination and antitermination
BBC0122_RS01510	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BBC0122_RS01520	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BBC0122_RS01555	COG2813	Specifically methylates the guanine in position
BBC0122_RS01560	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BBC0122_RS01570	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BBC0122_RS01600	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBC0122_RS01615	COG2816	NAD+ diphosphatase activity
BBC0122_RS01620	COG1605	Chorismate mutase
BBC0122_RS01620	COG0077	Prephenate dehydratase
BBC0122_RS01625	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BBC0122_RS01630	COG3474	cytochrome
BBC0122_RS01635	COG4166	transmembrane transport
BBC0122_RS01640	COG4174	ABC transporter (Permease)
BBC0122_RS01645	COG4239	(ABC) transporter, permease
BBC0122_RS01650	COG4172	Belongs to the ABC transporter superfamily
BBC0122_RS01660	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BBC0122_RS01665	COG0189	ligase activity
BBC0122_RS01670	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BBC0122_RS01675	COG0573	inorganic phosphate transmembrane transporter activity
BBC0122_RS01685	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BBC0122_RS01690	COG0704	Plays a role in the regulation of phosphate uptake
BBC0122_RS01705	COG4993	Dehydrogenase
BBC0122_RS01715	COG0717	Belongs to the dCTP deaminase family
BBC0122_RS01725	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BBC0122_RS01735	COG1663	tetraacyldisaccharide 4'-kinase activity
BBC0122_RS01740	COG1519	Transferase
BBC0122_RS01745	COG2121	Domain of unknown function (DUF374)
BBC0122_RS01755	COG0483	inositol monophosphate 1-phosphatase activity
BBC0122_RS01760	COG0312	modulator of DNA gyrase
BBC0122_RS01765	COG0612	Peptidase, M16
BBC0122_RS01770	COG0612	Peptidase, M16
BBC0122_RS01775	COG0742	ribosomal rna small subunit methyltransferase
BBC0122_RS01785	COG0590	tRNA wobble adenosine to inosine editing
BBC0122_RS01790	COG0656	L-ascorbic acid biosynthetic process
BBC0122_RS01805	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BBC0122_RS01810	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BBC0122_RS01820	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBC0122_RS01825	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BBC0122_RS01835	COG2309	aminopeptidase activity
BBC0122_RS01840	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BBC0122_RS01845	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BBC0122_RS01855	COG2181	nitrate reductase activity
BBC0122_RS01860	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BBC0122_RS01865	COG1140	nitrate reductase beta subunit
BBC0122_RS01870	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
BBC0122_RS01890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBC0122_RS01895	COG2900	Belongs to the SlyX family
BBC0122_RS01920	COG1116	anion transmembrane transporter activity
BBC0122_RS01920	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBC0122_RS01925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBC0122_RS01940	COG2329	Antibiotic biosynthesis monooxygenase
BBC0122_RS01950	COG4948	Mandelate Racemase Muconate Lactonizing
BBC0122_RS01955	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS01965	COG3962	Belongs to the TPP enzyme family
BBC0122_RS01970	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS01985	COG4975	Glucose uptake
BBC0122_RS02005	COG2010	Cytochrome c
BBC0122_RS02020	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BBC0122_RS02035	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BBC0122_RS02040	COG0477	Major facilitator Superfamily
BBC0122_RS02055	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBC0122_RS02080	COG2204	response regulator
BBC0122_RS02085	COG3852	Histidine kinase
BBC0122_RS02110	COG0583	DNA-binding transcription factor activity
BBC0122_RS02130	COG0583	DNA-binding transcription factor activity
BBC0122_RS02140	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBC0122_RS02160	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BBC0122_RS02170	COG1414	Transcriptional regulator
BBC0122_RS02190	COG1802	Transcriptional regulator
BBC0122_RS02200	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBC0122_RS02205	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBC0122_RS02210	COG1116	anion transmembrane transporter activity
BBC0122_RS02235	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBC0122_RS02270	COG0745	RESPONSE REGULATOR receiver
BBC0122_RS02275	COG2205	protein histidine kinase activity
BBC0122_RS02290	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BBC0122_RS02295	COG0477	Major facilitator Superfamily
BBC0122_RS02315	COG2086	electron transfer activity
BBC0122_RS02325	COG1960	acyl-CoA dehydrogenase activity
BBC0122_RS02330	COG0183	Belongs to the thiolase family
BBC0122_RS02365	COG2070	2-Nitropropane dioxygenase
BBC0122_RS02370	COG1024	Enoyl-CoA hydratase
BBC0122_RS02385	COG0667	Aldo Keto reductase
BBC0122_RS02395	COG3777	bacterial-type RNA polymerase transcription factor activity, metal ion regulated sequence-specific DNA binding
BBC0122_RS02405	COG0730	response to heat
BBC0122_RS02420	COG1201	RNA secondary structure unwinding
BBC0122_RS02430	COG2340	Cysteine-rich secretory protein family
BBC0122_RS02445	COG2818	Glycosylase
BBC0122_RS02460	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BBC0122_RS02480	COG0033	Phosphoglucomutase
BBC0122_RS02495	COG0459	protein refolding
BBC0122_RS02500	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BBC0122_RS02515	COG3920	Histidine kinase
BBC0122_RS02520	COG0180	Tryptophanyl-tRNA synthetase
BBC0122_RS02525	COG0728	peptidoglycan biosynthetic process
BBC0122_RS02540	COG0196	riboflavin kinase activity
BBC0122_RS02555	COG0431	NADPH-dependent FMN reductase
BBC0122_RS02570	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BBC0122_RS02580	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBC0122_RS02585	COG1684	flagellar biosynthetic protein fliR
BBC0122_RS02615	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BBC0122_RS02620	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BBC0122_RS02640	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BBC0122_RS02650	COG4786	Flagellar basal body rod
BBC0122_RS02655	COG1157	protein secretion by the type III secretion system
BBC0122_RS02665	COG1815	bacterial-type flagellum-dependent cell motility
BBC0122_RS02670	COG1558	bacterial-type flagellum-dependent cell motility
BBC0122_RS02680	COG1677	Flagellar hook-basal body complex protein FliE
BBC0122_RS02685	COG4786	Flagellar basal body rod
BBC0122_RS02690	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BBC0122_RS02695	COG1706	bacterial-type flagellum-dependent cell motility
BBC0122_RS02705	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BBC0122_RS02715	COG1338	Plays a role in the flagellum-specific transport system
BBC0122_RS02765	COG1360	Flagellar Motor Protein
BBC0122_RS02795	COG1256	bacterial-type flagellum assembly
BBC0122_RS02815	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BBC0122_RS02860	COG0248	Ppx GppA phosphatase
BBC0122_RS02860	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BBC0122_RS02865	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BBC0122_RS02875	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BBC0122_RS02880	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BBC0122_RS02885	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBC0122_RS02890	COG0799	negative regulation of ribosome biogenesis
BBC0122_RS02895	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BBC0122_RS02905	COG0793	Belongs to the peptidase S41A family
BBC0122_RS02910	COG0494	nUDIX hydrolase
BBC0122_RS02915	COG5342	invasion associated locus B
BBC0122_RS02920	COG2217	Heavy metal translocating P-type atpase
BBC0122_RS02925	COG0789	Transcriptional regulator
BBC0122_RS02950	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BBC0122_RS02955	COG1217	gtp-binding protein TYPA
BBC0122_RS02960	COG2239	Acts as a magnesium transporter
BBC0122_RS02970	COG0339	signal peptide processing
BBC0122_RS02975	COG0066	3-isopropylmalate dehydratase activity
BBC0122_RS02990	COG2951	lytic endotransglycosylase activity
BBC0122_RS02995	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BBC0122_RS03000	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BBC0122_RS03000	COG0517	IMP dehydrogenase activity
BBC0122_RS03005	COG1012	belongs to the aldehyde dehydrogenase family
BBC0122_RS03010	COG1063	alcohol dehydrogenase
BBC0122_RS03015	COG0753	catalase activity
BBC0122_RS03040	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BBC0122_RS03060	COG3189	MarR family transcriptional regulator
BBC0122_RS03065	COG0277	FAD linked oxidase domain protein
BBC0122_RS03070	COG0277	FAD linked oxidase domain protein
BBC0122_RS03090	COG2204	response regulator
BBC0122_RS03105	COG0330	HflC and HflK could
BBC0122_RS03110	COG1585	Membrane protein implicated in regulation of membrane protease activity
BBC0122_RS03130	COG0826	peptidase U32
BBC0122_RS03150	COG0642	Histidine kinase
BBC0122_RS03185	COG0527	aspartate kinase activity
BBC0122_RS03190	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BBC0122_RS03200	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BBC0122_RS03205	COG1040	competence protein
BBC0122_RS03215	COG1823	symporter activity
BBC0122_RS03225	COG0494	nUDIX hydrolase
BBC0122_RS03235	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BBC0122_RS03240	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BBC0122_RS03245	COG0653	protein targeting
BBC0122_RS03260	COG2890	protein-(glutamine-N5) methyltransferase activity
BBC0122_RS03265	COG2814	Major facilitator Superfamily
BBC0122_RS03275	COG1780	Probably involved in ribonucleotide reductase function
BBC0122_RS03280	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBC0122_RS03300	COG1573	uracil-dna glycosylase
BBC0122_RS03310	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BBC0122_RS03330	COG0659	secondary active sulfate transmembrane transporter activity
BBC0122_RS03335	COG0477	Major facilitator Superfamily
BBC0122_RS03340	COG0471	metal ion transport
BBC0122_RS03340	COG3273	potassium ion transport
BBC0122_RS03355	COG1160	GTP binding
BBC0122_RS03370	COG0356	it plays a direct role in the translocation of protons across the membrane
BBC0122_RS03380	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BBC0122_RS03385	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BBC0122_RS03400	COG3781	membrane
BBC0122_RS03405	COG0751	glycine-tRNA ligase activity
BBC0122_RS03420	COG0142	geranyltranstransferase activity
BBC0122_RS03430	COG0357	Ribosomal RNA small subunit methyltransferase G
BBC0122_RS03445	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BBC0122_RS03450	COG0521	Mo-molybdopterin cofactor biosynthetic process
BBC0122_RS03505	COG0009	L-threonylcarbamoyladenylate synthase
BBC0122_RS03510	COG0277	FAD linked oxidase domain protein
BBC0122_RS03530	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BBC0122_RS03555	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BBC0122_RS03575	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBC0122_RS03575	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BBC0122_RS03580	COG1722	exodeoxyribonuclease VII activity
BBC0122_RS03590	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBC0122_RS03595	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BBC0122_RS03605	COG2391	methyltransferase activity
BBC0122_RS03610	COG0312	modulator of DNA gyrase
BBC0122_RS03620	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BBC0122_RS03635	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BBC0122_RS03640	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BBC0122_RS03645	COG0328	RNA-DNA hybrid ribonuclease activity
BBC0122_RS03655	COG1678	Uncharacterized ACR, COG1678
BBC0122_RS03660	COG5001	Diguanylate cyclase
BBC0122_RS03660	COG3300	MHYT domain
BBC0122_RS03665	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBC0122_RS03670	COG0612	Peptidase, M16
BBC0122_RS03690	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BBC0122_RS03695	COG1194	a g-specific adenine glycosylase
BBC0122_RS03700	COG0477	Major facilitator Superfamily
BBC0122_RS03725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BBC0122_RS03725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BBC0122_RS03730	COG1196	nuclear chromosome segregation
BBC0122_RS03735	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBC0122_RS03735	COG0574	Belongs to the PEP-utilizing enzyme family
BBC0122_RS03750	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BBC0122_RS03750	COG0426	domain, Protein
BBC0122_RS03770	COG0598	Magnesium transport protein CorA
BBC0122_RS03780	COG0433	COG0433 Predicted ATPase
BBC0122_RS03785	COG1376	ErfK ybiS ycfS ynhG family protein
BBC0122_RS03790	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BBC0122_RS03810	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBC0122_RS03820	COG2166	iron-sulfur cluster assembly
BBC0122_RS03830	COG2205	protein histidine kinase activity
BBC0122_RS03880	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBC0122_RS03890	COG4235	cytochrome complex assembly
BBC0122_RS03895	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BBC0122_RS03900	COG1138	Cytochrome C-type biogenesis protein
BBC0122_RS03905	COG3088	subunit of a heme lyase
BBC0122_RS03910	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBC0122_RS03915	COG0745	RESPONSE REGULATOR receiver
BBC0122_RS03920	COG2205	protein histidine kinase activity
BBC0122_RS03925	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BBC0122_RS03930	COG2205	protein histidine kinase activity
BBC0122_RS03930	COG2202	Pas domain
BBC0122_RS03935	COG0308	aminopeptidase N
BBC0122_RS03965	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BBC0122_RS03980	COG2022	thiamine diphosphate biosynthetic process
BBC0122_RS04000	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BBC0122_RS04025	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBC0122_RS04035	COG0765	amino acid transport
BBC0122_RS04065	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBC0122_RS04080	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BBC0122_RS04085	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBC0122_RS04090	COG4558	Periplasmic binding protein
BBC0122_RS04095	COG3720	iron ion transport
BBC0122_RS04120	COG4932	domain protein
BBC0122_RS04120	COG2373	Large extracellular alpha-helical protein
BBC0122_RS04120	COG1388	LysM domain
BBC0122_RS04135	COG1388	LysM domain
BBC0122_RS04135	COG2373	Large extracellular alpha-helical protein
BBC0122_RS04135	COG4932	domain protein
BBC0122_RS04150	COG2373	Large extracellular alpha-helical protein
BBC0122_RS04150	COG4932	domain protein
BBC0122_RS04150	COG1388	LysM domain
BBC0122_RS04230	COG0741	lytic transglycosylase activity
BBC0122_RS04235	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBC0122_RS04240	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BBC0122_RS04245	COG1573	uracil-dna glycosylase
BBC0122_RS04255	COG1758	RNA polymerase activity
BBC0122_RS04270	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBC0122_RS04275	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BBC0122_RS04280	COG2223	nitrite transmembrane transporter activity
BBC0122_RS04295	COG0681	Belongs to the peptidase S26 family
BBC0122_RS04300	COG0571	ribonuclease III activity
BBC0122_RS04310	COG1381	Involved in DNA repair and RecF pathway recombination
BBC0122_RS04325	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BBC0122_RS04330	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BBC0122_RS04340	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BBC0122_RS04345	COG0354	folic acid binding
BBC0122_RS04350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBC0122_RS04385	COG0215	cysteine-tRNA ligase activity
BBC0122_RS04410	COG5265	(ABC) transporter
BBC0122_RS04415	COG0688	phosphatidylethanolamine metabolic process
BBC0122_RS04420	COG1183	phosphatidylcholine synthase activity
BBC0122_RS04425	COG4221	oxidoreductase activity
BBC0122_RS04430	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BBC0122_RS04445	COG0305	Participates in initiation and elongation during chromosome replication
BBC0122_RS04450	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBC0122_RS04470	COG0360	Binds together with S18 to 16S ribosomal RNA
BBC0122_RS04475	COG0671	phosphoesterase, PA-phosphatase related
BBC0122_RS04480	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBC0122_RS04495	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBC0122_RS04500	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BBC0122_RS04510	COG1561	YicC-like family, N-terminal region
BBC0122_RS04515	COG0194	GDP metabolic process
BBC0122_RS04520	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BBC0122_RS04525	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BBC0122_RS04535	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BBC0122_RS04565	COG0477	Major facilitator Superfamily
BBC0122_RS04570	COG0488	(ABC) transporter
BBC0122_RS04575	COG0105	UTP biosynthetic process
BBC0122_RS04585	COG0314	molybdopterin synthase activity
BBC0122_RS04595	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBC0122_RS04605	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS04615	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BBC0122_RS04630	COG0243	molybdopterin cofactor binding
BBC0122_RS04635	COG1472	Belongs to the glycosyl hydrolase 3 family
BBC0122_RS04645	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBC0122_RS04650	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBC0122_RS04660	COG0805	protein transport
BBC0122_RS04670	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BBC0122_RS04675	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BBC0122_RS04680	COG1388	LysM domain
BBC0122_RS04680	COG4942	peptidase
BBC0122_RS04690	COG1862	Preprotein translocase
BBC0122_RS04710	COG0303	'Molybdopterin
BBC0122_RS04715	COG0315	cyclic pyranopterin monophosphate synthase activity
BBC0122_RS04720	COG0134	indole-3-glycerol-phosphate synthase activity
BBC0122_RS04725	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBC0122_RS04735	COG0149	triose-phosphate isomerase activity
BBC0122_RS04740	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBC0122_RS04750	COG0504	CTP synthase activity
BBC0122_RS04760	COG0148	phosphopyruvate hydratase activity
BBC0122_RS04765	COG2314	TM2 domain
BBC0122_RS04770	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
BBC0122_RS04775	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBC0122_RS04780	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBC0122_RS04780	COG0022	dehydrogenase e1 component
BBC0122_RS04785	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBC0122_RS04795	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBC0122_RS04800	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BBC0122_RS04805	COG2867	negative regulation of translational initiation
BBC0122_RS04815	COG1058	Belongs to the CinA family
BBC0122_RS04815	COG1546	Belongs to the CinA family
BBC0122_RS04820	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BBC0122_RS04820	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BBC0122_RS04825	COG1959	2 iron, 2 sulfur cluster binding
BBC0122_RS04830	COG5000	phosphorelay sensor kinase activity
BBC0122_RS04835	COG2204	response regulator
BBC0122_RS04840	COG0569	domain protein
BBC0122_RS04850	COG0740	serine-type endopeptidase activity
BBC0122_RS04855	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BBC0122_RS04875	COG0546	phosphoglycolate phosphatase activity
BBC0122_RS04880	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BBC0122_RS04890	COG0544	peptidyl-prolyl cis-trans isomerase activity
BBC0122_RS04920	COG1376	ErfK ybiS ycfS ynhG family protein
BBC0122_RS04935	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBC0122_RS04950	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBC0122_RS04970	COG0250	Participates in transcription elongation, termination and antitermination
BBC0122_RS04980	COG0081	regulation of translation
BBC0122_RS04990	COG0222	ribosome binding
BBC0122_RS05000	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BBC0122_RS05035	COG1760	l-serine dehydratase
BBC0122_RS05050	COG1686	Belongs to the peptidase S11 family
BBC0122_RS05065	COG0537	adenosine 5'-monophosphoramidase activity
BBC0122_RS05085	COG0052	Belongs to the universal ribosomal protein uS2 family
BBC0122_RS05090	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BBC0122_RS05095	COG0528	UMP kinase activity
BBC0122_RS05115	COG0750	zinc metalloprotease
BBC0122_RS05120	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BBC0122_RS05125	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBC0122_RS05135	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBC0122_RS05145	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BBC0122_RS05150	COG1126	abc transporter atp-binding protein
BBC0122_RS05155	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBC0122_RS05170	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBC0122_RS05180	COG0583	DNA-binding transcription factor activity
BBC0122_RS05190	COG1473	amidohydrolase
BBC0122_RS05195	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BBC0122_RS05210	COG0330	HflC and HflK could
BBC0122_RS05220	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BBC0122_RS05225	COG0560	Phosphoserine phosphatase
BBC0122_RS05230	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BBC0122_RS05235	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBC0122_RS05245	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BBC0122_RS05250	COG1183	phosphatidylcholine synthase activity
BBC0122_RS05265	COG2989	Protein conserved in bacteria
BBC0122_RS05275	COG1612	heme a metabolic process
BBC0122_RS05285	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BBC0122_RS05290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBC0122_RS05295	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBC0122_RS05295	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BBC0122_RS05305	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BBC0122_RS05325	COG0416	fatty acid biosynthetic process
BBC0122_RS05330	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BBC0122_RS05335	COG0776	regulation of translation
BBC0122_RS05360	COG0483	inositol monophosphate 1-phosphatase activity
BBC0122_RS05370	COG0071	Belongs to the small heat shock protein (HSP20) family
BBC0122_RS05375	COG0070	glutamate synthase
BBC0122_RS05375	COG0067	glutamate synthase
BBC0122_RS05375	COG0069	glutamate synthase activity
BBC0122_RS05405	COG3956	TIGRFAM MazG family protein
BBC0122_RS05410	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBC0122_RS05430	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBC0122_RS05435	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BBC0122_RS05440	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BBC0122_RS05445	COG0280	phosphate acetyltransferase
BBC0122_RS05445	COG0281	malic enzyme
BBC0122_RS05450	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS05460	COG1127	ABC transporter
BBC0122_RS05470	COG3218	ABC-type transport auxiliary lipoprotein component
BBC0122_RS05470	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BBC0122_RS05480	COG0633	Ferredoxin
BBC0122_RS05490	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBC0122_RS05495	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBC0122_RS05535	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBC0122_RS05550	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BBC0122_RS05555	COG0028	Belongs to the TPP enzyme family
BBC0122_RS05560	COG0440	acetolactate synthase activity
BBC0122_RS05565	COG2070	2-Nitropropane dioxygenase
BBC0122_RS05570	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBC0122_RS05580	COG0372	Belongs to the citrate synthase family
BBC0122_RS05605	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BBC0122_RS05620	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BBC0122_RS05625	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BBC0122_RS05635	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BBC0122_RS05635	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBC0122_RS05640	COG0513	Belongs to the DEAD box helicase family
BBC0122_RS05665	COG1530	ribonuclease E activity
BBC0122_RS05675	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BBC0122_RS05695	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BBC0122_RS05705	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BBC0122_RS05710	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BBC0122_RS05715	COG2945	thiolester hydrolase activity
BBC0122_RS05725	COG0719	Fe-S assembly protein
BBC0122_RS05730	COG0396	ATPase activity
BBC0122_RS05735	COG0719	Fe-S assembly protein
BBC0122_RS05740	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBC0122_RS05745	COG2151	metal-sulfur cluster biosynthetic enzyme
BBC0122_RS05750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBC0122_RS05765	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BBC0122_RS05770	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BBC0122_RS05785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BBC0122_RS05790	COG0187	DNA topoisomerase II activity
BBC0122_RS05795	COG0463	Glycosyl transferase, family 2
BBC0122_RS05815	COG0321	lipoyl(octanoyl) transferase activity
BBC0122_RS05825	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BBC0122_RS05830	COG1704	LemA family
BBC0122_RS05845	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBC0122_RS05850	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBC0122_RS05855	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBC0122_RS05860	COG0649	NAD binding
BBC0122_RS05865	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BBC0122_RS05870	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BBC0122_RS05880	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BBC0122_RS05885	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BBC0122_RS05895	COG0713	ATP synthesis coupled electron transport
BBC0122_RS05910	COG1007	ATP synthesis coupled electron transport
BBC0122_RS05925	COG0442	prolyl-tRNA aminoacylation
BBC0122_RS05935	COG1136	(ABC) transporter
BBC0122_RS05955	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BBC0122_RS05965	COG4166	transmembrane transport
BBC0122_RS05975	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BBC0122_RS05990	COG1686	Belongs to the peptidase S11 family
BBC0122_RS05995	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BBC0122_RS06000	COG0470	DNA polymerase III
BBC0122_RS06005	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBC0122_RS06010	COG0084	hydrolase, TatD family'
BBC0122_RS06020	COG1120	ATPase activity
BBC0122_RS06025	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBC0122_RS06035	COG4607	ABC-type enterochelin transport system periplasmic component
BBC0122_RS06040	COG4774	siderophore transport
BBC0122_RS06040	COG1629	transport
BBC0122_RS06050	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BBC0122_RS06055	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBC0122_RS06070	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BBC0122_RS06075	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BBC0122_RS06080	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBC0122_RS06090	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BBC0122_RS06095	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BBC0122_RS06110	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BBC0122_RS06120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BBC0122_RS06125	COG1126	abc transporter atp-binding protein
BBC0122_RS06130	COG0765	amino acid transport
BBC0122_RS06135	COG4597	amino acid ABC transporter
BBC0122_RS06140	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBC0122_RS06145	COG0626	cystathionine gamma-synthase activity
BBC0122_RS06160	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BBC0122_RS06170	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBC0122_RS06175	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBC0122_RS06180	COG0785	Cytochrome C biogenesis protein
BBC0122_RS06195	COG2879	small protein
BBC0122_RS06200	COG1966	Carbon starvation protein
BBC0122_RS06220	COG3381	protein complex oligomerization
BBC0122_RS06250	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBC0122_RS06260	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BBC0122_RS06275	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BBC0122_RS06280	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BBC0122_RS06290	COG0316	Belongs to the HesB IscA family
BBC0122_RS06295	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BBC0122_RS06300	COG0018	arginyl-trna synthetase
BBC0122_RS06310	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBC0122_RS06315	COG1494	fructose-1,6-bisphosphatase
BBC0122_RS06325	COG0436	Aminotransferase
BBC0122_RS06375	COG0628	permease
BBC0122_RS06380	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BBC0122_RS06385	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BBC0122_RS06425	COG3106	COG3106 Predicted ATPase
BBC0122_RS06430	COG3768	UPF0283 membrane protein
BBC0122_RS06450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBC0122_RS06465	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BBC0122_RS06470	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBC0122_RS06475	COG0047	phosphoribosylformylglycinamidine synthase activity
BBC0122_RS06485	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBC0122_RS06495	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BBC0122_RS06500	COG2814	Major facilitator Superfamily
BBC0122_RS06505	COG0037	tRNA processing
BBC0122_RS06510	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BBC0122_RS06525	COG0024	Methionine aminopeptidase
BBC0122_RS06530	COG2003	Belongs to the UPF0758 family
BBC0122_RS06545	COG0596	Alpha beta hydrolase
BBC0122_RS06555	COG1278	Cold shock
BBC0122_RS06560	COG0346	lactoylglutathione lyase activity
BBC0122_RS06570	COG0559	Belongs to the binding-protein-dependent transport system permease family
BBC0122_RS06590	COG0154	amidase activity
BBC0122_RS06595	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BBC0122_RS06600	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BBC0122_RS06605	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BBC0122_RS06615	COG0540	Belongs to the ATCase OTCase family
BBC0122_RS06620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBC0122_RS06625	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BBC0122_RS06630	COG0758	DNA mediated transformation
BBC0122_RS06635	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBC0122_RS06635	COG1754	DNA topoisomerase type I activity
BBC0122_RS06640	COG0557	exoribonuclease II activity
BBC0122_RS06650	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BBC0122_RS06660	COG0746	molybdenum cofactor guanylyltransferase activity
BBC0122_RS06670	COG0625	glutathione transferase activity
BBC0122_RS06690	COG1573	uracil-dna glycosylase
BBC0122_RS06695	COG1522	sequence-specific DNA binding
BBC0122_RS06700	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BBC0122_RS06705	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BBC0122_RS06720	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BBC0122_RS06725	COG0436	Aminotransferase
BBC0122_RS06740	COG0511	ligase activity, forming carbon-carbon bonds
BBC0122_RS06770	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BBC0122_RS06780	COG1113	amino acid transport
BBC0122_RS06795	COG0738	Major facilitator superfamily
BBC0122_RS06805	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS06815	COG4948	Mandelate Racemase Muconate Lactonizing
BBC0122_RS06820	COG2271	Major facilitator Superfamily
BBC0122_RS06830	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS06835	COG2186	Transcriptional regulator
BBC0122_RS06850	COG2999	glutathione oxidoreductase activity
BBC0122_RS06860	COG0538	isocitrate dehydrogenase activity
BBC0122_RS06875	COG2814	Major facilitator Superfamily
BBC0122_RS06890	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BBC0122_RS06895	COG2099	Precorrin-6x reductase
BBC0122_RS06945	COG1492	cobalamin metabolic process
BBC0122_RS06955	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBC0122_RS06960	COG0343	queuine tRNA-ribosyltransferase activity
BBC0122_RS06985	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BBC0122_RS06990	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBC0122_RS06995	COG2095	MarC family integral membrane protein
BBC0122_RS07005	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBC0122_RS07015	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BBC0122_RS07015	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BBC0122_RS07020	COG0347	Belongs to the P(II) protein family
BBC0122_RS07025	COG0174	glutamine synthetase
BBC0122_RS07040	COG1764	response to oxidative stress
BBC0122_RS07050	COG0546	phosphoglycolate phosphatase activity
BBC0122_RS07060	COG1132	(ABC) transporter
BBC0122_RS07065	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BBC0122_RS07075	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BBC0122_RS07080	COG2885	chlorophyll binding
BBC0122_RS07085	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BBC0122_RS07095	COG0203	ribosomal protein L17
BBC0122_RS07110	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BBC0122_RS07115	COG0563	adenylate kinase activity
BBC0122_RS07120	COG0201	protein transport
BBC0122_RS07125	COG0200	Binds to the 23S rRNA
BBC0122_RS07130	COG1841	ribosomal large subunit assembly
BBC0122_RS07135	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BBC0122_RS07140	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BBC0122_RS07145	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BBC0122_RS07155	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBC0122_RS07160	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BBC0122_RS07165	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BBC0122_RS07170	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BBC0122_RS07175	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BBC0122_RS07185	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BBC0122_RS07190	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BBC0122_RS07200	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BBC0122_RS07205	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BBC0122_RS07215	COG0088	Forms part of the polypeptide exit tunnel
BBC0122_RS07220	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BBC0122_RS07230	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BBC0122_RS07235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BBC0122_RS07240	COG0049	tRNA binding
BBC0122_RS07255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBC0122_RS07260	COG0765	amino acid transport
BBC0122_RS07265	COG0765	amino acid transport
BBC0122_RS07270	COG1126	abc transporter atp-binding protein
BBC0122_RS07310	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BBC0122_RS07325	COG0625	glutathione transferase activity
BBC0122_RS07340	COG1609	Transcriptional regulator
BBC0122_RS07345	COG4993	Dehydrogenase
BBC0122_RS07350	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BBC0122_RS07355	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BBC0122_RS07365	COG0535	radical SAM domain protein
BBC0122_RS07370	COG0583	DNA-binding transcription factor activity
BBC0122_RS07375	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BBC0122_RS07380	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BBC0122_RS07385	COG3485	protocatechuate 3,4-dioxygenase
BBC0122_RS07390	COG3485	protocatechuate 3,4-dioxygenase
BBC0122_RS07405	COG0673	inositol 2-dehydrogenase activity
BBC0122_RS07410	COG1053	succinate dehydrogenase
BBC0122_RS07415	COG1053	succinate dehydrogenase
BBC0122_RS07415	COG3976	FMN-binding domain protein
BBC0122_RS07425	COG0477	Major facilitator Superfamily
BBC0122_RS07440	COG0683	leucine binding
BBC0122_RS07470	COG2897	thiosulfate sulfurtransferase activity
BBC0122_RS07475	COG0513	Belongs to the DEAD box helicase family
BBC0122_RS07490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBC0122_RS07505	COG1196	nuclear chromosome segregation
BBC0122_RS07505	COG3264	Mechanosensitive ion channel
BBC0122_RS07515	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BBC0122_RS07520	COG4651	solute:proton antiporter activity
BBC0122_RS07520	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BBC0122_RS07540	COG1253	flavin adenine dinucleotide binding
BBC0122_RS07560	COG2814	Major facilitator Superfamily
BBC0122_RS07570	COG1309	transcriptional regulator
BBC0122_RS07595	COG2050	protein possibly involved in aromatic compounds catabolism
BBC0122_RS07600	COG1024	Enoyl-CoA hydratase
BBC0122_RS07605	COG1012	belongs to the aldehyde dehydrogenase family
BBC0122_RS07605	COG2030	dehydratase
BBC0122_RS07615	COG3396	Phenylacetate-CoA oxygenase
BBC0122_RS07620	COG3460	Phenylacetate-CoA oxygenase
BBC0122_RS07625	COG3396	Phenylacetate-CoA oxygenase
BBC0122_RS07630	COG2151	metal-sulfur cluster biosynthetic enzyme
BBC0122_RS07635	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BBC0122_RS07645	COG1309	transcriptional regulator
BBC0122_RS07650	COG2271	Major facilitator Superfamily
BBC0122_RS07655	COG1012	belongs to the aldehyde dehydrogenase family
BBC0122_RS07665	COG1960	acyl-CoA dehydrogenase activity
BBC0122_RS07675	COG1024	Enoyl-CoA hydratase
BBC0122_RS07690	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BBC0122_RS07700	COG0384	phenazine biosynthesis protein PhzF
BBC0122_RS07715	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BBC0122_RS07725	COG3158	transport of potassium into the cell
BBC0122_RS07740	COG1301	dicarboxylic acid transport
BBC0122_RS07785	COG0028	Belongs to the TPP enzyme family
BBC0122_RS07805	COG1999	signal sequence binding
BBC0122_RS07815	COG0006	proline dipeptidase activity
BBC0122_RS07820	COG0697	spore germination
BBC0122_RS07830	COG0497	DNA recombination
BBC0122_RS07835	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BBC0122_RS07855	COG0849	cell division
BBC0122_RS07865	COG1181	Belongs to the D-alanine--D-alanine ligase family
BBC0122_RS07875	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBC0122_RS07880	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BBC0122_RS07885	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BBC0122_RS07895	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBC0122_RS07900	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBC0122_RS07910	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BBC0122_RS07925	COG0275	rRNA processing
BBC0122_RS07930	COG1914	H( )-stimulated, divalent metal cation uptake system
BBC0122_RS07945	COG3023	N-Acetylmuramoyl-L-alanine amidase
BBC0122_RS07950	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BBC0122_RS07990	COG2226	methyltransferase
BBC0122_RS08010	COG1376	ErfK ybiS ycfS ynhG family protein
BBC0122_RS08015	COG4106	trans-aconitate 2-methyltransferase activity
BBC0122_RS08035	COG1335	isochorismatase
BBC0122_RS08040	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BBC0122_RS08045	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BBC0122_RS08070	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBC0122_RS08100	COG1388	LysM domain
BBC0122_RS08100	COG2373	Large extracellular alpha-helical protein
BBC0122_RS08100	COG4932	domain protein
BBC0122_RS08105	COG2373	Large extracellular alpha-helical protein
BBC0122_RS08105	COG4932	domain protein
BBC0122_RS08105	COG1388	LysM domain
BBC0122_RS08115	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BBC0122_RS08145	COG4172	Belongs to the ABC transporter superfamily
BBC0122_RS08150	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBC0122_RS08155	COG0601	transmembrane transport
BBC0122_RS08195	COG0477	Major facilitator Superfamily
BBC0122_RS08205	COG1454	alcohol dehydrogenase
BBC0122_RS08210	COG1012	belongs to the aldehyde dehydrogenase family
BBC0122_RS08225	COG2968	Membrane
BBC0122_RS08230	COG2983	Belongs to the UPF0260 family
BBC0122_RS08240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBC0122_RS08265	COG0505	Belongs to the CarA family
BBC0122_RS08285	COG2321	neutral zinc metallopeptidase
BBC0122_RS08310	COG0672	)-iron permease
BBC0122_RS08325	COG1278	Cold shock
BBC0122_RS08340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBC0122_RS08355	COG0436	Aminotransferase
BBC0122_RS08375	COG0583	DNA-binding transcription factor activity
BBC0122_RS08380	COG0492	ferredoxin-NADP+ reductase activity
BBC0122_RS08385	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBC0122_RS08390	COG1522	sequence-specific DNA binding
BBC0122_RS08415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBC0122_RS08435	COG0556	nucleotide-excision repair
BBC0122_RS08440	COG1278	Cold shock
BBC0122_RS08460	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBC0122_RS08470	COG0745	RESPONSE REGULATOR receiver
BBC0122_RS08475	COG2205	protein histidine kinase activity
BBC0122_RS08485	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BBC0122_RS08500	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BBC0122_RS08510	COG1496	oxidoreductase activity
BBC0122_RS08515	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BBC0122_RS08530	COG0193	aminoacyl-tRNA hydrolase activity
BBC0122_RS08535	COG1376	ErfK ybiS ycfS ynhG family protein
BBC0122_RS08535	COG1388	LysM domain
BBC0122_RS08540	COG0012	GTP binding
BBC0122_RS08555	COG2857	Cytochrome c1
BBC0122_RS08555	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BBC0122_RS08570	COG1132	(ABC) transporter
BBC0122_RS08575	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BBC0122_RS08585	COG0617	tRNA 3'-terminal CCA addition
BBC0122_RS08595	COG0714	Associated with various cellular activities
BBC0122_RS08620	COG3047	cAMP biosynthetic process
BBC0122_RS08645	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BBC0122_RS08650	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBC0122_RS08650	COG0512	Glutamine amidotransferase of anthranilate synthase
BBC0122_RS08665	COG3448	diguanylate cyclase activity
BBC0122_RS08665	COG4175	Glycine betaine
BBC0122_RS08675	COG0482	sulfurtransferase activity
BBC0122_RS08725	COG2252	PERMEase
BBC0122_RS08735	COG0673	inositol 2-dehydrogenase activity
BBC0122_RS08750	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BBC0122_RS08770	COG0166	Belongs to the GPI family
BBC0122_RS08780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BBC0122_RS08790	COG5000	phosphorelay sensor kinase activity
BBC0122_RS08805	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BBC0122_RS08815	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBC0122_RS08820	COG0656	L-ascorbic acid biosynthetic process
BBC0122_RS08860	COG2072	flavoprotein involved in K transport
BBC0122_RS08875	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBC0122_RS08885	COG3257	ureidoglycine aminohydrolase activity
BBC0122_RS08925	COG0534	Mate efflux family protein
BBC0122_RS08930	COG0477	Major facilitator Superfamily
BBC0122_RS08950	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BBC0122_RS08955	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BBC0122_RS08990	COG1518	maintenance of DNA repeat elements
BBC0122_RS08995	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
BBC0122_RS09005	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBC0122_RS09010	COG1120	ATPase activity
BBC0122_RS09015	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBC0122_RS09040	COG1105	Belongs to the carbohydrate kinase PfkB family
BBC0122_RS09045	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBC0122_RS09045	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBC0122_RS09050	COG1609	Transcriptional regulator
BBC0122_RS09060	COG1064	alcohol dehydrogenase
BBC0122_RS09070	COG4771	TonB-dependent receptor
BBC0122_RS09080	COG4607	ABC-type enterochelin transport system periplasmic component
BBC0122_RS09085	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BBC0122_RS09095	COG4604	ABC transporter, ATP-binding protein
BBC0122_RS09100	COG2814	Major facilitator Superfamily
BBC0122_RS09105	COG0025	NhaP-type Na H and K H
BBC0122_RS09365	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBC0122_RS09385	COG0792	nuclease activity
BBC0122_RS09390	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BBC0122_RS09395	COG0427	acetyl-CoA hydrolase
BBC0122_RS09410	COG0489	protein tyrosine kinase activity
BBC0122_RS09430	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BBC0122_RS09445	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BBC0122_RS09460	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BBC0122_RS09475	COG0837	glucose binding
BBC0122_RS09545	COG2161	toxin-antitoxin pair type II binding
BBC0122_RS09595	COG2831	hemolysin activation secretion protein
BBC0122_RS09635	COG0577	efflux transmembrane transporter activity
BBC0122_RS09635	COG1136	(ABC) transporter
BBC0122_RS09640	COG0577	efflux transmembrane transporter activity
BBC0122_RS09640	COG1136	(ABC) transporter
BBC0122_RS09660	COG0745	RESPONSE REGULATOR receiver
BBC0122_RS09665	COG5002	protein histidine kinase activity
BBC0122_RS09665	COG3850	Histidine kinase
BBC0122_RS09905	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBC0122_RS09910	COG3344	reverse transcriptase
BBC0122_RS09945	COG0741	lytic transglycosylase activity
BBC0122_RS09960	COG3451	type IV secretory pathway VirB4
BBC0122_RS09995	COG2948	multi-organism process
BBC0122_RS10000	COG4962	Type ii secretion system protein e
BBC0122_RS10005	COG3505	Type IV secretory pathway VirD4
BBC0122_RS10035	COG4957	zinc ion binding
BBC0122_RS10070	COG1012	belongs to the aldehyde dehydrogenase family
BBC0122_RS10075	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS10085	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBC0122_RS10090	COG0765	amino acid transport
BBC0122_RS10095	COG0765	amino acid transport
BBC0122_RS10100	COG1126	abc transporter atp-binding protein
BBC0122_RS10110	COG1802	Transcriptional regulator
BBC0122_RS10130	COG2382	esterase
BBC0122_RS10135	COG4774	siderophore transport
BBC0122_RS10195	COG2274	protein secretion by the type I secretion system
BBC0122_RS10205	COG0644	oxidoreductase
BBC0122_RS10215	COG2271	Major facilitator Superfamily
BBC0122_RS10220	COG0235	Class ii aldolase
BBC0122_RS10225	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BBC0122_RS10230	COG1349	DNA-binding transcription factor activity
BBC0122_RS10235	COG3622	Belongs to the hyi family
BBC0122_RS10240	COG3395	kinase activity
BBC0122_RS10245	COG2084	Dehydrogenase
BBC0122_RS10265	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBC0122_RS10270	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BBC0122_RS10290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBC0122_RS10300	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BBC0122_RS10310	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BBC0122_RS10320	COG0667	Aldo Keto reductase
BBC0122_RS10325	COG3618	amidohydrolase
BBC0122_RS10350	COG2362	D-Aminopeptidase
BBC0122_RS10360	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBC0122_RS10375	COG0747	negative chemotaxis
BBC0122_RS10380	COG4172	Belongs to the ABC transporter superfamily
BBC0122_RS10395	COG4770	biotin carboxylase activity
BBC0122_RS10400	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BBC0122_RS10405	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BBC0122_RS10410	COG1802	Transcriptional regulator
BBC0122_RS10420	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS10450	COG1132	(ABC) transporter
BBC0122_RS10450	COG2375	cellular response to nickel ion
BBC0122_RS10465	COG1620	l-lactate permease
BBC0122_RS10470	COG1304	FMN binding
BBC0122_RS10485	COG1116	anion transmembrane transporter activity
BBC0122_RS10485	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BBC0122_RS10495	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBC0122_RS10500	COG1733	regulation of RNA biosynthetic process
BBC0122_RS10505	COG2814	Major facilitator Superfamily
BBC0122_RS10510	COG0583	DNA-binding transcription factor activity
BBC0122_RS10515	COG4988	ABC transporter
BBC0122_RS10520	COG1132	(ABC) transporter
BBC0122_RS10525	COG1271	oxidase subunit
BBC0122_RS10530	COG1294	oxidase, subunit
BBC0122_RS10575	COG3971	2-oxopent-4-enoate hydratase activity
BBC0122_RS10580	COG1414	Transcriptional regulator
BBC0122_RS10585	COG2814	Major facilitator Superfamily
BBC0122_RS10650	COG1388	LysM domain
BBC0122_RS10650	COG4932	domain protein
BBC0122_RS10650	COG2373	Large extracellular alpha-helical protein
BBC0122_RS10715	COG1121	(ABC) transporter
BBC0122_RS10720	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBC0122_RS10725	COG0735	belongs to the Fur family
BBC0122_RS10760	COG0583	DNA-binding transcription factor activity
BBC0122_RS10770	COG0800	Aldolase
BBC0122_RS10795	COG2233	PERMEase
BBC0122_RS10800	COG0789	Transcriptional regulator
BBC0122_RS10805	COG1304	FMN binding
BBC0122_RS10810	COG1522	sequence-specific DNA binding
BBC0122_RS10820	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBC0122_RS10830	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBC0122_RS10830	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BBC0122_RS10835	COG0509	glycine decarboxylation via glycine cleavage system
BBC0122_RS10840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BBC0122_RS10845	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BBC0122_RS10860	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BBC0122_RS10865	COG2835	tetraacyldisaccharide 4'-kinase activity
BBC0122_RS10875	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BBC0122_RS10890	COG1464	Belongs to the NlpA lipoprotein family
BBC0122_RS10895	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBC0122_RS10900	COG2011	ABC-type metal ion transport system permease component
BBC0122_RS10910	COG2183	response to ionizing radiation
BBC0122_RS10915	COG1902	pentaerythritol trinitrate reductase activity
BBC0122_RS10925	COG0523	cobalamin synthesis protein
BBC0122_RS10935	COG1846	Transcriptional regulator
BBC0122_RS10940	COG1609	Transcriptional regulator
BBC0122_RS10945	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBC0122_RS10985	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BBC0122_RS11010	COG1289	transmembrane transporter activity
BBC0122_RS11025	COG0656	L-ascorbic acid biosynthetic process
BBC0122_RS11030	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BBC0122_RS11035	COG2258	MOSC domain
BBC0122_RS11060	COG0583	DNA-binding transcription factor activity
BBC0122_RS11065	COG1380	Effector of murein hydrolase LrgA
BBC0122_RS11070	COG1346	cytolysis
BBC0122_RS11075	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BBC0122_RS11080	COG0129	dihydroxy-acid dehydratase activity
BBC0122_RS11085	COG0363	glucosamine-6-phosphate deaminase activity
BBC0122_RS11090	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BBC0122_RS11095	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BBC0122_RS11100	COG0174	glutamine synthetase
BBC0122_RS11115	COG0167	dihydroorotate dehydrogenase activity
BBC0122_RS11130	COG1970	mechanosensitive ion channel activity
BBC0122_RS11150	COG1522	sequence-specific DNA binding
BBC0122_RS11170	COG0564	pseudouridine synthase activity
BBC0122_RS11175	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBC0122_RS11185	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BBC0122_RS11190	COG2271	Major facilitator Superfamily
BBC0122_RS11205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBC0122_RS11230	COG0831	urea catabolic process
BBC0122_RS11240	COG0832	Belongs to the urease beta subunit family
BBC0122_RS11245	COG0804	urea catabolic process
BBC0122_RS11250	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BBC0122_RS11255	COG0830	nickel cation binding
BBC0122_RS11260	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BBC0122_RS11290	COG0657	acetylesterase activity
BBC0122_RS11340	COG4942	peptidase
BBC0122_RS11355	COG0784	Response regulator, receiver
BBC0122_RS11380	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BBC0122_RS11385	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BBC0122_RS11395	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BBC0122_RS11430	COG1376	ErfK ybiS ycfS ynhG family protein
BBC0122_RS11440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BBC0122_RS11445	COG1393	Belongs to the ArsC family
BBC0122_RS11455	COG1238	metal cluster binding
BBC0122_RS11465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BBC0122_RS11480	COG0756	dUTP diphosphatase activity
BBC0122_RS11490	COG2864	formate dehydrogenase
BBC0122_RS11495	COG0437	4 iron, 4 sulfur cluster binding
BBC0122_RS11525	COG1921	L-seryl-tRNASec selenium transferase activity
BBC0122_RS11540	COG0848	biopolymer transport protein
BBC0122_RS11570	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BBC0122_RS11575	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBC0122_RS11580	COG0037	tRNA processing
BBC0122_RS11590	COG2885	chlorophyll binding
BBC0122_RS11595	COG0823	Involved in the tonB-independent uptake of proteins
BBC0122_RS11620	COG0604	alcohol dehydrogenase
BBC0122_RS11645	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBC0122_RS11650	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BBC0122_RS11655	COG0457	Tetratricopeptide repeat
BBC0122_RS11675	COG1692	metallophosphoesterase
BBC0122_RS11690	COG1132	(ABC) transporter
BBC0122_RS11700	COG0483	inositol monophosphate 1-phosphatase activity
BBC0122_RS11705	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BBC0122_RS11730	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BBC0122_RS11735	COG0632	four-way junction helicase activity
BBC0122_RS11740	COG2255	four-way junction helicase activity
BBC0122_RS11745	COG0824	Thioesterase
BBC0122_RS11750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBC0122_RS11765	COG3588	fructose-bisphosphate aldolase
BBC0122_RS11770	COG0126	phosphoglycerate kinase activity
BBC0122_RS11795	COG0469	pyruvate kinase activity
BBC0122_RS11815	COG0488	(ABC) transporter
BBC0122_RS11845	COG1329	Transcriptional regulator
BBC0122_RS11850	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BBC0122_RS11865	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BBC0122_RS11875	COG0142	geranyltranstransferase activity
BBC0122_RS11885	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BBC0122_RS11950	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BBC0122_RS11955	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BBC0122_RS11985	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBC0122_RS12000	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBC0122_RS12005	COG1028	Short-chain dehydrogenase reductase Sdr
BBC0122_RS12010	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BBC0122_RS12020	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBC0122_RS12035	COG3920	Histidine kinase
BBC0122_RS12035	COG2202	Pas domain
BBC0122_RS12040	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BBC0122_RS12045	COG2884	Cell division ATP-binding protein ftsE
BBC0122_RS12060	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBC0122_RS12065	COG1136	(ABC) transporter
BBC0122_RS12065	COG0577	efflux transmembrane transporter activity
BBC0122_RS12070	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BBC0122_RS12095	COG0004	ammonium transporteR
BBC0122_RS12100	COG0347	Belongs to the P(II) protein family
BBC0122_RS12110	COG1946	Acyl-CoA thioesterase
BBC0122_RS12115	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BBC0122_RS12155	COG0335	large ribosomal subunit rRNA binding
BBC0122_RS12160	COG0336	Belongs to the RNA methyltransferase TrmD family
BBC0122_RS12255	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BBC0122_RS12255	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BBC0122_RS12260	COG0501	Belongs to the peptidase M48B family
BBC0122_RS12265	COG5508	conserved small protein
BBC0122_RS12275	COG0228	four-way junction DNA binding
BBC0122_RS12285	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BBC0122_RS12295	COG0288	reversible hydration of carbon dioxide
BBC0122_RS12310	COG3703	Catalyzes the cleavage of glutathione into 5-oxo-L- proline and a Cys-Gly dipeptide. Acts specifically on glutathione, but not on other gamma-glutamyl peptides
BBC0122_RS12315	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BBC0122_RS12315	COG0519	Catalyzes the synthesis of GMP from XMP
BBC0122_RS12340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BBC0122_RS12360	COG2264	protein methyltransferase activity
BBC0122_RS12370	COG3034	peptidoglycan biosynthetic process
BBC0122_RS12380	COG0523	cobalamin synthesis protein
BBC0122_RS12385	COG1686	Belongs to the peptidase S11 family
BBC0122_RS12390	COG0589	response to stress
BBC0122_RS12395	COG1268	BioY protein
BBC0122_RS12405	COG1122	ATPase activity
BBC0122_RS12435	COG0351	phosphomethylpyrimidine kinase
BBC0122_RS12450	COG0471	metal ion transport
BBC0122_RS12475	COG3527	Alpha-acetolactate decarboxylase
BBC0122_RS12535	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BBC0122_RS12545	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BBC0122_RS12550	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BBC0122_RS12560	COG0287	Prephenate dehydrogenase
BBC0122_RS12570	COG2212	antiporter activity
BBC0122_RS12575	COG1863	multisubunit Na H antiporter MnhE subunit
BBC0122_RS12580	COG0651	ATP synthesis coupled electron transport
BBC0122_RS12585	COG1006	Multisubunit Na H antiporter MnhC subunit
BBC0122_RS12590	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BBC0122_RS12590	COG2111	Na H antiporter
BBC0122_RS12600	COG0019	diaminopimelate decarboxylase activity
BBC0122_RS12620	COG1280	lysine exporter protein (LysE YggA)
BBC0122_RS12630	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBC0122_RS12635	COG0567	Dehydrogenase, E1 component
BBC0122_RS12640	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BBC0122_RS12645	COG0045	succinate-CoA ligase (ADP-forming) activity
BBC0122_RS12650	COG0039	L-malate dehydrogenase activity
BBC0122_RS12655	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BBC0122_RS12665	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBC0122_RS12670	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BBC0122_RS12675	COG0552	protein localization to endoplasmic reticulum
BBC0122_RS12685	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BBC0122_RS12705	COG0357	Ribosomal RNA small subunit methyltransferase G
BBC0122_RS12710	COG0445	tRNA wobble uridine modification
BBC0122_RS12715	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BBC0122_RS12720	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BBC0122_RS12725	COG1981	membrane
BBC0122_RS12730	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BBC0122_RS12770	COG4932	domain protein
BBC0122_RS12770	COG1388	LysM domain
BBC0122_RS12770	COG2373	Large extracellular alpha-helical protein
BBC0122_RS12850	COG4605	iron ion homeostasis
BBC0122_RS13130	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BBC0122_RS13150	COG0842	Transport permease protein
BBC0122_RS13190	COG0400	carboxylic ester hydrolase activity
BBC0122_RS13265	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBC0122_RS13265	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBC0122_RS13305	COG0646	methionine synthase
BBC0122_RS13305	COG1410	methionine synthase
BBC0122_RS13310	COG0594	ribonuclease P activity