locus-tag	class	description
LNM86_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LNM86_RS00020	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LNM86_RS00025	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LNM86_RS00030	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LNM86_RS00035	COG1845	cytochrome c oxidase, subunit III
LNM86_RS00040	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LNM86_RS00045	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LNM86_RS00050	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LNM86_RS00060	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LNM86_RS00075	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LNM86_RS00080	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LNM86_RS00105	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LNM86_RS00110	COG0166	Belongs to the GPI family
LNM86_RS00120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LNM86_RS00125	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LNM86_RS00130	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LNM86_RS00130	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LNM86_RS00170	COG3657	addiction module killer protein
LNM86_RS00185	COG0582	viral genome integration into host DNA
LNM86_RS00190	COG3561	AntA/AntB antirepressor
LNM86_RS00220	COG3657	addiction module killer protein
LNM86_RS00410	COG3646	Phage regulatory protein
LNM86_RS00430	COG1598	PFAM Uncharacterised protein family UPF0150
LNM86_RS00560	COG3657	addiction module killer protein
LNM86_RS00575	COG0582	viral genome integration into host DNA
LNM86_RS00580	COG3561	AntA/AntB antirepressor
LNM86_RS00610	COG3657	addiction module killer protein
LNM86_RS00800	COG3646	Phage regulatory protein
LNM86_RS00820	COG1598	PFAM Uncharacterised protein family UPF0150
LNM86_RS00925	COG2814	Major facilitator Superfamily
LNM86_RS00970	COG0248	Ppx GppA phosphatase
LNM86_RS00975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LNM86_RS00980	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LNM86_RS00985	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LNM86_RS00990	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LNM86_RS00995	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LNM86_RS01000	COG0799	negative regulation of ribosome biogenesis
LNM86_RS01005	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LNM86_RS01015	COG0793	Belongs to the peptidase S41A family
LNM86_RS01020	COG0494	nUDIX hydrolase
LNM86_RS01025	COG5342	invasion associated locus B
LNM86_RS01035	COG1872	DUF167
LNM86_RS01040	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LNM86_RS01045	COG1217	gtp-binding protein TYPA
LNM86_RS01050	COG2239	Acts as a magnesium transporter
LNM86_RS01055	COG0339	signal peptide processing
LNM86_RS01070	COG2951	lytic endotransglycosylase activity
LNM86_RS01075	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LNM86_RS01080	COG0517	IMP dehydrogenase activity
LNM86_RS01080	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LNM86_RS01090	COG2204	response regulator
LNM86_RS01095	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LNM86_RS01105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LNM86_RS01105	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LNM86_RS01110	COG0519	Catalyzes the synthesis of GMP from XMP
LNM86_RS01110	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LNM86_RS01115	COG0584	glycerophosphoryl diester phosphodiesterase
LNM86_RS01120	COG3842	ATPase activity
LNM86_RS01125	COG0395	ABC-type sugar transport system, permease component
LNM86_RS01130	COG1175	transmembrane transport
LNM86_RS01140	COG0803	Belongs to the bacterial solute-binding protein 9 family
LNM86_RS01160	COG1780	Probably involved in ribonucleotide reductase function
LNM86_RS01165	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LNM86_RS01175	COG2890	protein-(glutamine-N5) methyltransferase activity
LNM86_RS01180	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LNM86_RS01190	COG0653	protein targeting
LNM86_RS01195	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LNM86_RS01200	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LNM86_RS01205	COG0494	nUDIX hydrolase
LNM86_RS01220	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LNM86_RS01225	COG1072	(Pantothenic acid kinase))
LNM86_RS01230	COG0252	asparaginase activity
LNM86_RS01235	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LNM86_RS01240	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LNM86_RS01250	COG1185	polyribonucleotide nucleotidyltransferase activity
LNM86_RS01255	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LNM86_RS01270	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LNM86_RS01275	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LNM86_RS01280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LNM86_RS01295	COG0779	Required for maturation of 30S ribosomal subunits
LNM86_RS01300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LNM86_RS01305	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LNM86_RS01310	COG1396	sequence-specific DNA binding
LNM86_RS01325	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LNM86_RS01330	COG1702	phosphate starvation-inducible protein PhoH
LNM86_RS01335	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LNM86_RS01345	COG1214	PFAM Peptidase M22, glycoprotease
LNM86_RS01350	COG2855	membrane
LNM86_RS01355	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LNM86_RS01360	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LNM86_RS01365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LNM86_RS01380	COG1605	Chorismate mutase
LNM86_RS01380	COG0077	Prephenate dehydratase
LNM86_RS01385	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LNM86_RS01390	COG3474	cytochrome
LNM86_RS01415	COG0189	ligase activity
LNM86_RS01425	COG0573	inorganic phosphate transmembrane transporter activity
LNM86_RS01435	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LNM86_RS01440	COG0704	Plays a role in the regulation of phosphate uptake
LNM86_RS01455	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LNM86_RS01480	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LNM86_RS01485	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LNM86_RS01490	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LNM86_RS01495	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LNM86_RS01510	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LNM86_RS01515	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LNM86_RS01525	COG0590	tRNA wobble adenosine to inosine editing
LNM86_RS01535	COG0742	ribosomal rna small subunit methyltransferase
LNM86_RS01540	COG3959	Transketolase, thiamine diphosphate binding domain
LNM86_RS01550	COG3958	Transketolase
LNM86_RS01555	COG1304	FMN binding
LNM86_RS01560	COG0717	Belongs to the dCTP deaminase family
LNM86_RS01565	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LNM86_RS01575	COG1663	tetraacyldisaccharide 4'-kinase activity
LNM86_RS01580	COG1519	Transferase
LNM86_RS01590	COG0483	inositol monophosphate 1-phosphatase activity
LNM86_RS01595	COG0312	modulator of DNA gyrase
LNM86_RS01605	COG1673	EVE domain
LNM86_RS01690	COG4680	protein conserved in bacteria
LNM86_RS01840	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
LNM86_RS01845	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LNM86_RS01855	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNM86_RS01860	COG0564	pseudouridine synthase activity
LNM86_RS01875	COG2205	protein histidine kinase activity
LNM86_RS01880	COG1970	mechanosensitive ion channel activity
LNM86_RS01885	COG0167	dihydroorotate dehydrogenase activity
LNM86_RS01920	COG0534	Mate efflux family protein
LNM86_RS01925	COG0174	glutamine synthetase
LNM86_RS01935	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LNM86_RS01940	COG0363	glucosamine-6-phosphate deaminase activity
LNM86_RS01945	COG0129	dihydroxy-acid dehydratase activity
LNM86_RS01950	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LNM86_RS01975	COG1823	symporter activity
LNM86_RS01985	COG1040	competence protein
LNM86_RS01990	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LNM86_RS01995	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LNM86_RS02000	COG0527	aspartate kinase activity
LNM86_RS02010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LNM86_RS02020	COG0471	metal ion transport
LNM86_RS02020	COG3273	potassium ion transport
LNM86_RS02030	COG1160	GTP binding
LNM86_RS02040	COG0356	it plays a direct role in the translocation of protons across the membrane
LNM86_RS02050	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LNM86_RS02055	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LNM86_RS02075	COG0149	triose-phosphate isomerase activity
LNM86_RS02085	COG0504	CTP synthase activity
LNM86_RS02090	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LNM86_RS02095	COG0148	phosphopyruvate hydratase activity
LNM86_RS02105	COG2314	TM2 domain
LNM86_RS02115	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LNM86_RS02120	COG0508	dehydrogenase complex catalyzes the overall conversion of
LNM86_RS02120	COG0022	dehydrogenase e1 component
LNM86_RS02125	COG0508	dehydrogenase complex catalyzes the overall conversion of
LNM86_RS02130	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LNM86_RS02135	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LNM86_RS02140	COG2867	negative regulation of translational initiation
LNM86_RS02145	COG1058	Belongs to the CinA family
LNM86_RS02145	COG1546	Belongs to the CinA family
LNM86_RS02155	COG1959	2 iron, 2 sulfur cluster binding
LNM86_RS02160	COG5000	phosphorelay sensor kinase activity
LNM86_RS02165	COG2204	response regulator
LNM86_RS02170	COG0569	domain protein
LNM86_RS02180	COG0740	serine-type endopeptidase activity
LNM86_RS02185	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LNM86_RS02200	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LNM86_RS02210	COG0544	peptidyl-prolyl cis-trans isomerase activity
LNM86_RS02215	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LNM86_RS02225	COG4765	Protein conserved in bacteria
LNM86_RS02240	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LNM86_RS02255	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LNM86_RS02265	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LNM86_RS02275	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LNM86_RS02280	COG0081	regulation of translation
LNM86_RS02285	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LNM86_RS02290	COG0222	ribosome binding
LNM86_RS02295	COG0085	RNA polymerase activity
LNM86_RS02300	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LNM86_RS02315	COG1760	l-serine dehydratase
LNM86_RS02330	COG1686	Belongs to the peptidase S11 family
LNM86_RS02335	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LNM86_RS02360	COG0052	Belongs to the universal ribosomal protein uS2 family
LNM86_RS02365	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LNM86_RS02370	COG0528	UMP kinase activity
LNM86_RS02375	COG0233	cytoplasmic translational termination
LNM86_RS02385	COG0750	zinc metalloprotease
LNM86_RS02390	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LNM86_RS02395	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LNM86_RS02400	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LNM86_RS02405	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LNM86_RS02415	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LNM86_RS02420	COG1126	abc transporter atp-binding protein
LNM86_RS02430	COG4215	(ABC) transporter
LNM86_RS02435	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LNM86_RS02440	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LNM86_RS02445	COG0372	Belongs to the citrate synthase family
LNM86_RS02450	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LNM86_RS02455	COG0658	competence protein
LNM86_RS02455	COG2333	competence protein COMEC
LNM86_RS02465	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LNM86_RS02480	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LNM86_RS02490	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LNM86_RS02490	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LNM86_RS02495	COG0513	Belongs to the DEAD box helicase family
LNM86_RS02510	COG2986	histidine ammonia-lyase
LNM86_RS02535	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS02545	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS02550	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS02575	COG0582	viral genome integration into host DNA
LNM86_RS02625	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LNM86_RS02630	COG1138	Cytochrome C-type biogenesis protein
LNM86_RS02640	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LNM86_RS02650	COG0642	Histidine kinase
LNM86_RS02655	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LNM86_RS02660	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LNM86_RS02670	COG2205	protein histidine kinase activity
LNM86_RS02670	COG2202	Pas domain
LNM86_RS02675	COG0308	aminopeptidase N
LNM86_RS02685	COG0351	phosphomethylpyrimidine kinase
LNM86_RS02685	COG0352	thiamine-phosphate diphosphorylase activity
LNM86_RS02685	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
LNM86_RS02695	COG2022	thiamine diphosphate biosynthetic process
LNM86_RS02710	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LNM86_RS02720	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LNM86_RS02725	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNM86_RS02730	COG4558	Periplasmic binding protein
LNM86_RS02735	COG3720	iron ion transport
LNM86_RS02755	COG0741	lytic transglycosylase activity
LNM86_RS02760	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LNM86_RS02765	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LNM86_RS02770	COG1573	uracil-dna glycosylase
LNM86_RS02795	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS02830	COG1758	RNA polymerase activity
LNM86_RS02840	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LNM86_RS02850	COG0736	holo-[acyl-carrier-protein] synthase activity
LNM86_RS02855	COG0681	Belongs to the peptidase S26 family
LNM86_RS02860	COG0571	ribonuclease III activity
LNM86_RS02870	COG1381	Involved in DNA repair and RecF pathway recombination
LNM86_RS02875	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LNM86_RS02880	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LNM86_RS02890	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LNM86_RS02895	COG0354	folic acid binding
LNM86_RS02900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LNM86_RS02910	COG0215	cysteine-tRNA ligase activity
LNM86_RS02920	COG5265	(ABC) transporter
LNM86_RS02925	COG0688	phosphatidylethanolamine metabolic process
LNM86_RS02930	COG1183	phosphatidylcholine synthase activity
LNM86_RS02935	COG1028	Short-chain dehydrogenase reductase Sdr
LNM86_RS02940	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LNM86_RS02955	COG0305	Participates in initiation and elongation during chromosome replication
LNM86_RS02960	COG0359	binds to the 23S rRNA
LNM86_RS02970	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LNM86_RS02975	COG0360	Binds together with S18 to 16S ribosomal RNA
LNM86_RS02980	COG0671	phosphoesterase, PA-phosphatase related
LNM86_RS03010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03075	COG2814	Major facilitator Superfamily
LNM86_RS03085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LNM86_RS03085	COG0473	3-isopropylmalate dehydrogenase activity
LNM86_RS03155	COG2900	Belongs to the SlyX family
LNM86_RS03165	COG1113	amino acid transport
LNM86_RS03170	COG1122	ATPase activity
LNM86_RS03180	COG1268	BioY protein
LNM86_RS03190	COG1268	BioY protein
LNM86_RS03195	COG0312	modulator of DNA gyrase
LNM86_RS03205	COG0109	protoheme IX farnesyltransferase activity
LNM86_RS03210	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LNM86_RS03215	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LNM86_RS03220	COG0328	RNA-DNA hybrid ribonuclease activity
LNM86_RS03230	COG1678	Uncharacterized ACR, COG1678
LNM86_RS03240	COG0612	Peptidase, M16
LNM86_RS03270	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LNM86_RS03280	COG1194	a g-specific adenine glycosylase
LNM86_RS03290	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LNM86_RS03290	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LNM86_RS03295	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LNM86_RS03295	COG0574	Belongs to the PEP-utilizing enzyme family
LNM86_RS03315	COG2166	iron-sulfur cluster assembly
LNM86_RS03330	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LNM86_RS03375	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LNM86_RS03395	COG4555	ABC transporter
LNM86_RS03515	COG0629	single-stranded DNA binding
LNM86_RS03540	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03565	COG0582	viral genome integration into host DNA
LNM86_RS03595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03625	COG0582	viral genome integration into host DNA
LNM86_RS03645	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03655	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03685	COG0582	viral genome integration into host DNA
LNM86_RS03710	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LNM86_RS03715	COG3657	addiction module killer protein
LNM86_RS03725	COG0582	viral genome integration into host DNA
LNM86_RS03750	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03800	COG0741	lytic transglycosylase activity
LNM86_RS03820	COG0582	viral genome integration into host DNA
LNM86_RS03850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03875	COG0582	viral genome integration into host DNA
LNM86_RS03910	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS03960	COG0588	phosphoglycerate mutase activity
LNM86_RS03965	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LNM86_RS03975	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LNM86_RS03985	COG0594	ribonuclease P activity
LNM86_RS03990	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LNM86_RS03995	COG0489	protein tyrosine kinase activity
LNM86_RS04000	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LNM86_RS04005	COG0792	nuclease activity
LNM86_RS04035	COG2086	electron transfer activity
LNM86_RS04045	COG0730	response to heat
LNM86_RS04065	COG0747	negative chemotaxis
LNM86_RS04070	COG0747	negative chemotaxis
LNM86_RS04075	COG0747	negative chemotaxis
LNM86_RS04095	COG0519	Catalyzes the synthesis of GMP from XMP
LNM86_RS04100	COG1570	exodeoxyribonuclease VII activity
LNM86_RS04110	COG0751	glycine-tRNA ligase activity
LNM86_RS04125	COG0142	geranyltranstransferase activity
LNM86_RS04140	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LNM86_RS04145	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LNM86_RS04150	COG0009	L-threonylcarbamoyladenylate synthase
LNM86_RS04155	COG0277	FAD linked oxidase domain protein
LNM86_RS04180	COG0259	pyridoxamine-phosphate oxidase activity
LNM86_RS04185	COG0484	heat shock protein binding
LNM86_RS04190	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LNM86_RS04195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LNM86_RS04200	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LNM86_RS04200	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LNM86_RS04205	COG1722	exodeoxyribonuclease VII activity
LNM86_RS04210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LNM86_RS04255	COG0582	viral genome integration into host DNA
LNM86_RS04315	COG0582	viral genome integration into host DNA
LNM86_RS04365	COG0582	viral genome integration into host DNA
LNM86_RS04390	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LNM86_RS04400	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LNM86_RS04405	COG1113	amino acid transport
LNM86_RS04410	COG1113	amino acid transport
LNM86_RS04450	COG3077	Addiction module antitoxin, RelB DinJ family
LNM86_RS04470	COG1475	DNA binding
LNM86_RS04480	COG2801	Transposase and inactivated derivatives
LNM86_RS04485	COG2842	Transposition protein
LNM86_RS04515	COG3179	chitinase
LNM86_RS04550	COG4373	Mu-like prophage FluMu protein gp28
LNM86_RS04555	COG4383	Mu-like prophage protein gp29
LNM86_RS04560	COG2369	cell adhesion
LNM86_RS04680	COG1253	flavin adenine dinucleotide binding
LNM86_RS04690	COG4651	solute:proton antiporter activity
LNM86_RS04690	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LNM86_RS04705	COG3264	Mechanosensitive ion channel
LNM86_RS04705	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LNM86_RS04715	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LNM86_RS04725	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LNM86_RS04735	COG0513	Belongs to the DEAD box helicase family
LNM86_RS04750	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LNM86_RS04765	COG0525	valine-tRNA ligase activity
LNM86_RS04775	COG1126	abc transporter atp-binding protein
LNM86_RS04780	COG0765	amino acid transport
LNM86_RS04785	COG0765	amino acid transport
LNM86_RS04800	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LNM86_RS04805	COG0049	tRNA binding
LNM86_RS04810	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LNM86_RS04815	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LNM86_RS04820	COG0051	transcription antitermination factor activity, RNA binding
LNM86_RS04825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LNM86_RS04830	COG0088	Forms part of the polypeptide exit tunnel
LNM86_RS04835	COG0089	rRNA binding
LNM86_RS04840	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LNM86_RS04845	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LNM86_RS04850	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LNM86_RS04855	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LNM86_RS04860	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LNM86_RS04865	COG0255	Belongs to the universal ribosomal protein uL29 family
LNM86_RS04870	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LNM86_RS04875	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LNM86_RS04880	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LNM86_RS04885	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LNM86_RS04890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LNM86_RS04895	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LNM86_RS04900	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LNM86_RS04905	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LNM86_RS04910	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LNM86_RS04915	COG1841	ribosomal large subunit assembly
LNM86_RS04920	COG0200	Binds to the 23S rRNA
LNM86_RS04930	COG0563	adenylate kinase activity
LNM86_RS04935	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LNM86_RS04940	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LNM86_RS04945	COG0202	RNA polymerase activity
LNM86_RS04950	COG0203	ribosomal protein L17
LNM86_RS04955	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LNM86_RS04960	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LNM86_RS04965	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LNM86_RS04970	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LNM86_RS04975	COG1132	(ABC) transporter
LNM86_RS04995	COG0174	glutamine synthetase
LNM86_RS05000	COG0347	Belongs to the P(II) protein family
LNM86_RS05010	COG0629	single-stranded DNA binding
LNM86_RS05015	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LNM86_RS05020	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LNM86_RS05035	COG0343	queuine tRNA-ribosyltransferase activity
LNM86_RS05040	COG2814	Major facilitator Superfamily
LNM86_RS05050	COG0538	isocitrate dehydrogenase activity
LNM86_RS05075	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LNM86_RS05090	COG0018	arginyl-trna synthetase
LNM86_RS05095	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LNM86_RS05100	COG0316	Belongs to the HesB IscA family
LNM86_RS05115	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LNM86_RS05120	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LNM86_RS05125	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LNM86_RS05135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LNM86_RS05145	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LNM86_RS05150	COG0248	Ppx GppA phosphatase
LNM86_RS05155	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LNM86_RS05160	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LNM86_RS05165	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LNM86_RS05170	COG2814	Major facilitator Superfamily
LNM86_RS05175	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LNM86_RS05185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LNM86_RS05190	COG0047	phosphoribosylformylglycinamidine synthase activity
LNM86_RS05195	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LNM86_RS05200	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LNM86_RS05210	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LNM86_RS05220	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LNM86_RS05240	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LNM86_RS05245	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LNM86_RS05250	COG0628	permease
LNM86_RS05430	COG3561	AntA/AntB antirepressor
LNM86_RS05480	COG3077	Addiction module antitoxin, RelB DinJ family
LNM86_RS05485	COG3041	Addiction module toxin RelE StbE family
LNM86_RS05495	COG3561	AntA/AntB antirepressor
LNM86_RS05525	COG1598	PFAM Uncharacterised protein family UPF0150
LNM86_RS05670	COG0071	Belongs to the small heat shock protein (HSP20) family
LNM86_RS05690	COG3956	TIGRFAM MazG family protein
LNM86_RS05700	COG1063	alcohol dehydrogenase
LNM86_RS05705	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LNM86_RS05715	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LNM86_RS05720	COG0281	malic enzyme
LNM86_RS05720	COG0280	phosphate acetyltransferase
LNM86_RS05730	COG1923	regulation of RNA biosynthetic process
LNM86_RS05735	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LNM86_RS05745	COG1612	heme a metabolic process
LNM86_RS05750	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LNM86_RS05755	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LNM86_RS05760	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LNM86_RS05765	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LNM86_RS05765	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LNM86_RS05775	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LNM86_RS05780	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LNM86_RS05795	COG0416	fatty acid biosynthetic process
LNM86_RS05800	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LNM86_RS05805	COG0776	regulation of translation
LNM86_RS05815	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LNM86_RS05820	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LNM86_RS05830	COG0302	gtp cyclohydrolase
LNM86_RS05840	COG0582	viral genome integration into host DNA
LNM86_RS05925	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS05930	COG0629	single-stranded DNA binding
LNM86_RS05980	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LNM86_RS05985	COG3657	addiction module killer protein
LNM86_RS05995	COG0582	viral genome integration into host DNA
LNM86_RS06070	COG0741	lytic transglycosylase activity
LNM86_RS06165	COG0477	Major facilitator Superfamily
LNM86_RS06190	COG1942	4-Oxalocrotonate Tautomerase
LNM86_RS06230	COG0305	Participates in initiation and elongation during chromosome replication
LNM86_RS06250	COG1475	DNA binding
LNM86_RS06260	COG2801	Transposase and inactivated derivatives
LNM86_RS06265	COG2842	Transposition protein
LNM86_RS06295	COG3179	chitinase
LNM86_RS06330	COG4373	Mu-like prophage FluMu protein gp28
LNM86_RS06335	COG4383	Mu-like prophage protein gp29
LNM86_RS06340	COG2369	cell adhesion
LNM86_RS06565	COG0629	single-stranded DNA binding
LNM86_RS06590	COG1598	PFAM Uncharacterised protein family UPF0150
LNM86_RS06595	COG3561	AntA/AntB antirepressor
LNM86_RS06650	COG3561	AntA/AntB antirepressor
LNM86_RS06695	COG0511	ligase activity, forming carbon-carbon bonds
LNM86_RS06720	COG1522	sequence-specific DNA binding
LNM86_RS06725	COG1573	uracil-dna glycosylase
LNM86_RS06735	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LNM86_RS06740	COG0557	exoribonuclease II activity
LNM86_RS06745	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LNM86_RS06755	COG0758	DNA mediated transformation
LNM86_RS06760	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LNM86_RS06765	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LNM86_RS06770	COG0540	Belongs to the ATCase OTCase family
LNM86_RS06780	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LNM86_RS06785	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LNM86_RS06790	COG0154	amidase activity
LNM86_RS06820	COG1278	Cold shock
LNM86_RS06830	COG0596	Alpha beta hydrolase
LNM86_RS06840	COG2003	Belongs to the UPF0758 family
LNM86_RS06845	COG0024	Methionine aminopeptidase
LNM86_RS06850	COG1489	DNA binding
LNM86_RS06860	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LNM86_RS06865	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LNM86_RS06870	COG0037	tRNA processing
LNM86_RS06880	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LNM86_RS06900	COG0582	viral genome integration into host DNA
LNM86_RS06925	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LNM86_RS06935	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LNM86_RS06940	COG0084	hydrolase, TatD family'
LNM86_RS06945	COG0321	lipoyl(octanoyl) transferase activity
LNM86_RS06945	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LNM86_RS06960	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LNM86_RS06965	COG1183	phosphatidylcholine synthase activity
LNM86_RS06970	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LNM86_RS07005	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LNM86_RS07010	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LNM86_RS07020	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LNM86_RS07025	COG0719	Fe-S assembly protein
LNM86_RS07030	COG0396	ATPase activity
LNM86_RS07035	COG0719	Fe-S assembly protein
LNM86_RS07045	COG2945	thiolester hydrolase activity
LNM86_RS07050	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LNM86_RS07055	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LNM86_RS07065	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LNM86_RS07070	COG0860	N-Acetylmuramoyl-L-alanine amidase
LNM86_RS07075	COG1530	ribonuclease E activity
LNM86_RS07090	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LNM86_RS07095	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LNM86_RS07100	COG1136	(ABC) transporter
LNM86_RS07110	COG0442	prolyl-tRNA aminoacylation
LNM86_RS07125	COG1007	ATP synthesis coupled electron transport
LNM86_RS07140	COG0713	ATP synthesis coupled electron transport
LNM86_RS07150	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LNM86_RS07155	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LNM86_RS07165	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LNM86_RS07170	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LNM86_RS07175	COG0649	NAD binding
LNM86_RS07180	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LNM86_RS07185	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LNM86_RS07190	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LNM86_RS07250	COG1862	Preprotein translocase
LNM86_RS07255	COG4942	peptidase
LNM86_RS07255	COG1388	LysM domain
LNM86_RS07260	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LNM86_RS07265	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LNM86_RS07270	COG0805	protein transport
LNM86_RS07275	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LNM86_RS07280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LNM86_RS07285	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LNM86_RS07290	COG0322	excinuclease ABC activity
LNM86_RS07295	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LNM86_RS07300	COG0105	UTP biosynthetic process
LNM86_RS07305	COG3468	outer membrane autotransporter barrel domain protein
LNM86_RS07315	COG3468	outer membrane autotransporter barrel domain protein
LNM86_RS07320	COG0477	Major facilitator Superfamily
LNM86_RS07345	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LNM86_RS07355	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LNM86_RS07360	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LNM86_RS07370	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LNM86_RS07375	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LNM86_RS07380	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LNM86_RS07390	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LNM86_RS07515	COG2369	cell adhesion
LNM86_RS07520	COG4383	Mu-like prophage protein gp29
LNM86_RS07525	COG4373	Mu-like prophage FluMu protein gp28
LNM86_RS07560	COG3179	chitinase
LNM86_RS07590	COG2842	Transposition protein
LNM86_RS07595	COG2801	Transposase and inactivated derivatives
LNM86_RS07605	COG1475	DNA binding
LNM86_RS07640	COG0482	sulfurtransferase activity
LNM86_RS07740	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LNM86_RS07745	COG0601	transmembrane transport
LNM86_RS07750	COG0747	negative chemotaxis
LNM86_RS07755	COG0747	negative chemotaxis
LNM86_RS07770	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LNM86_RS07775	COG0321	lipoyl(octanoyl) transferase activity
LNM86_RS07780	COG0187	DNA topoisomerase II activity
LNM86_RS07785	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
LNM86_RS07790	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LNM86_RS07795	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LNM86_RS07800	COG0784	Response regulator, receiver
LNM86_RS07815	COG3468	outer membrane autotransporter barrel domain protein
LNM86_RS07835	COG0477	Major facilitator Superfamily
LNM86_RS07880	COG0735	belongs to the Fur family
LNM86_RS07910	COG1054	Belongs to the UPF0176 family
LNM86_RS07915	COG0800	Aldolase
LNM86_RS07955	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LNM86_RS07955	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LNM86_RS07960	COG0509	glycine decarboxylation via glycine cleavage system
LNM86_RS07965	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LNM86_RS07975	COG2835	tetraacyldisaccharide 4'-kinase activity
LNM86_RS07980	COG1396	sequence-specific DNA binding
LNM86_RS07990	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LNM86_RS08010	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LNM86_RS08015	COG2011	ABC-type metal ion transport system permease component
LNM86_RS08055	COG0523	cobalamin synthesis protein
LNM86_RS08085	COG4607	ABC-type enterochelin transport system periplasmic component
LNM86_RS08090	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LNM86_RS08095	COG4605	iron ion homeostasis
LNM86_RS08100	COG4604	ABC transporter, ATP-binding protein
LNM86_RS08150	COG3561	AntA/AntB antirepressor
LNM86_RS08220	COG0629	single-stranded DNA binding
LNM86_RS08310	COG0582	viral genome integration into host DNA
LNM86_RS08340	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS08365	COG0028	Belongs to the TPP enzyme family
LNM86_RS08370	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LNM86_RS08380	COG0330	HflC and HflK could
LNM86_RS08395	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LNM86_RS08400	COG0477	Major facilitator Superfamily
LNM86_RS08410	COG0477	Major facilitator Superfamily
LNM86_RS08415	COG0477	Major facilitator Superfamily
LNM86_RS08455	COG1999	signal sequence binding
LNM86_RS08465	COG0006	proline dipeptidase activity
LNM86_RS08485	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LNM86_RS08495	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LNM86_RS08510	COG0849	cell division
LNM86_RS08520	COG1181	Belongs to the D-alanine--D-alanine ligase family
LNM86_RS08525	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LNM86_RS08530	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LNM86_RS08535	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LNM86_RS08545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LNM86_RS08550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LNM86_RS08560	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LNM86_RS08575	COG0275	rRNA processing
LNM86_RS08595	COG2226	methyltransferase
LNM86_RS08610	COG1335	isochorismatase
LNM86_RS08650	COG2968	Membrane
LNM86_RS08660	COG2983	Belongs to the UPF0260 family
LNM86_RS08665	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNM86_RS08675	COG0668	transmembrane transport
LNM86_RS08695	COG3161	chorismate lyase activity
LNM86_RS08705	COG0505	Belongs to the CarA family
LNM86_RS08735	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS08765	COG0582	viral genome integration into host DNA
LNM86_RS08790	COG1278	Cold shock
LNM86_RS08800	COG0436	Aminotransferase
LNM86_RS08805	COG0583	DNA-binding transcription factor activity
LNM86_RS08810	COG0492	ferredoxin-NADP+ reductase activity
LNM86_RS08815	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LNM86_RS08825	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LNM86_RS08835	COG0556	nucleotide-excision repair
LNM86_RS08850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LNM86_RS08855	COG0745	RESPONSE REGULATOR receiver
LNM86_RS08860	COG2205	protein histidine kinase activity
LNM86_RS08875	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LNM86_RS08900	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LNM86_RS08905	COG0193	aminoacyl-tRNA hydrolase activity
LNM86_RS08910	COG1376	ErfK ybiS ycfS ynhG family protein
LNM86_RS08915	COG0012	GTP binding
LNM86_RS08925	COG2857	Cytochrome c1
LNM86_RS08925	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LNM86_RS08935	COG0723	plastoquinol--plastocyanin reductase activity
LNM86_RS08940	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LNM86_RS08945	COG0617	tRNA 3'-terminal CCA addition
LNM86_RS08950	COG0714	Associated with various cellular activities
LNM86_RS08970	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LNM86_RS08975	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LNM86_RS08980	COG0582	viral genome integration into host DNA
LNM86_RS09020	COG0305	Participates in initiation and elongation during chromosome replication
LNM86_RS09075	COG1192	Involved in chromosome partitioning
LNM86_RS09115	COG0196	riboflavin kinase activity
LNM86_RS09135	COG3838	Conjugal transfer protein Trbc
LNM86_RS09140	COG3702	type iv secretory pathway
LNM86_RS09145	COG3451	type IV secretory pathway VirB4
LNM86_RS09155	COG3704	protein secretion by the type IV secretion system
LNM86_RS09165	COG3736	Type IV secretory pathway, component VirB8
LNM86_RS09170	COG3504	Conjugal transfer protein
LNM86_RS09175	COG2948	multi-organism process
LNM86_RS09180	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LNM86_RS09190	COG2184	nucleotidyltransferase activity
LNM86_RS09195	COG2184	nucleotidyltransferase activity
LNM86_RS09200	COG3505	Type IV secretory pathway VirD4
LNM86_RS09205	COG2184	nucleotidyltransferase activity
LNM86_RS09230	COG2184	nucleotidyltransferase activity
LNM86_RS09235	COG2184	nucleotidyltransferase activity
LNM86_RS09240	COG0728	peptidoglycan biosynthetic process
LNM86_RS09245	COG0180	Tryptophanyl-tRNA synthetase
LNM86_RS09255	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LNM86_RS09285	COG2824	Alkylphosphonate utilization operon protein PhnA
LNM86_RS09295	COG0459	protein refolding
LNM86_RS09300	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LNM86_RS09310	COG0033	Phosphoglucomutase
LNM86_RS09325	COG0124	histidyl-tRNA synthetase
LNM86_RS09330	COG0284	orotidine-5'-phosphate decarboxylase activity
LNM86_RS09420	COG0784	Response regulator, receiver
LNM86_RS09565	COG0582	viral genome integration into host DNA
LNM86_RS09595	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS09600	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS09615	COG1396	sequence-specific DNA binding
LNM86_RS09625	COG1396	sequence-specific DNA binding
LNM86_RS09630	COG1396	sequence-specific DNA binding
LNM86_RS09660	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LNM86_RS09665	COG0424	maF-like protein
LNM86_RS09670	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LNM86_RS09695	COG3838	Conjugal transfer protein Trbc
LNM86_RS09700	COG3702	type iv secretory pathway
LNM86_RS09710	COG0582	viral genome integration into host DNA
LNM86_RS09745	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS09770	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS09815	COG0582	viral genome integration into host DNA
LNM86_RS09850	COG3704	protein secretion by the type IV secretion system
LNM86_RS09860	COG3736	Type IV secretory pathway, component VirB8
LNM86_RS09865	COG3504	Conjugal transfer protein
LNM86_RS09870	COG2948	multi-organism process
LNM86_RS09875	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LNM86_RS09905	COG3077	Addiction module antitoxin, RelB DinJ family
LNM86_RS09945	COG3505	Type IV secretory pathway VirD4
LNM86_RS09990	COG1396	sequence-specific DNA binding
LNM86_RS09995	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LNM86_RS10010	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LNM86_RS10020	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LNM86_RS10025	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LNM86_RS10030	COG0457	Tetratricopeptide repeat
LNM86_RS10045	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
LNM86_RS10050	COG1692	metallophosphoesterase
LNM86_RS10060	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LNM86_RS10405	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LNM86_RS10420	COG1238	metal cluster binding
LNM86_RS10445	COG0756	dUTP diphosphatase activity
LNM86_RS10460	COG0848	biopolymer transport protein
LNM86_RS10465	COG0811	peptide transport
LNM86_RS10470	COG1396	sequence-specific DNA binding
LNM86_RS10490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LNM86_RS10495	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LNM86_RS10510	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LNM86_RS10515	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LNM86_RS10520	COG0037	tRNA processing
LNM86_RS10530	COG2885	chlorophyll binding
LNM86_RS10540	COG0217	transcriptional regulatory protein
LNM86_RS10545	COG0823	Involved in the tonB-independent uptake of proteins
LNM86_RS10565	COG0824	Thioesterase
LNM86_RS10570	COG2255	four-way junction helicase activity
LNM86_RS10575	COG0632	four-way junction helicase activity
LNM86_RS10580	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LNM86_RS10585	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LNM86_RS10605	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LNM86_RS10620	COG1396	sequence-specific DNA binding
LNM86_RS10665	COG1396	sequence-specific DNA binding
LNM86_RS10680	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS10690	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS10720	COG0582	viral genome integration into host DNA
LNM86_RS10725	COG1396	sequence-specific DNA binding
LNM86_RS10740	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LNM86_RS10745	COG0483	inositol monophosphate 1-phosphatase activity
LNM86_RS10755	COG1132	(ABC) transporter
LNM86_RS10760	COG0254	rRNA binding
LNM86_RS10775	COG3588	fructose-bisphosphate aldolase
LNM86_RS10780	COG0126	phosphoglycerate kinase activity
LNM86_RS10820	COG0469	pyruvate kinase activity
LNM86_RS10830	COG3750	Belongs to the UPF0335 family
LNM86_RS10860	COG0488	(ABC) transporter
LNM86_RS10875	COG4783	chaperone-mediated protein folding
LNM86_RS10880	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LNM86_RS10890	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LNM86_RS10905	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LNM86_RS10910	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LNM86_RS10915	COG0142	geranyltranstransferase activity
LNM86_RS10935	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LNM86_RS10945	COG1566	PFAM secretion protein HlyD family protein
LNM86_RS10955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LNM86_RS10960	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LNM86_RS10965	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LNM86_RS10970	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LNM86_RS10975	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LNM86_RS10990	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LNM86_RS11015	COG0495	leucyl-tRNA aminoacylation
LNM86_RS11030	COG2884	Cell division ATP-binding protein ftsE
LNM86_RS11070	COG1136	(ABC) transporter
LNM86_RS11070	COG0577	efflux transmembrane transporter activity
LNM86_RS11075	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LNM86_RS11095	COG1674	ftsk spoiiie
LNM86_RS11100	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LNM86_RS11285	COG2948	multi-organism process
LNM86_RS11335	COG0582	viral genome integration into host DNA
LNM86_RS11370	COG0335	large ribosomal subunit rRNA binding
LNM86_RS11375	COG0336	Belongs to the RNA methyltransferase TrmD family
LNM86_RS11380	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LNM86_RS11420	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LNM86_RS11455	COG0138	bifunctional purine biosynthesis protein purh
LNM86_RS11465	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LNM86_RS11465	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LNM86_RS11470	COG0501	Belongs to the peptidase M48B family
LNM86_RS11475	COG5508	conserved small protein
LNM86_RS11480	COG0228	four-way junction DNA binding
LNM86_RS11490	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LNM86_RS11495	COG0288	reversible hydration of carbon dioxide
LNM86_RS11500	COG2902	Dehydrogenase
LNM86_RS11520	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
LNM86_RS11535	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LNM86_RS11555	COG0287	Prephenate dehydrogenase
LNM86_RS11565	COG1671	Belongs to the UPF0178 family
LNM86_RS11570	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LNM86_RS11575	COG0165	Argininosuccinate lyase
LNM86_RS11595	COG2226	methyltransferase
LNM86_RS11610	COG0745	RESPONSE REGULATOR receiver
LNM86_RS11620	COG1122	ATPase activity
LNM86_RS11745	COG2369	cell adhesion
LNM86_RS11750	COG4383	Mu-like prophage protein gp29
LNM86_RS11755	COG4373	Mu-like prophage FluMu protein gp28
LNM86_RS11790	COG3179	chitinase
LNM86_RS11820	COG2842	Transposition protein
LNM86_RS11825	COG2801	Transposase and inactivated derivatives
LNM86_RS11835	COG1475	DNA binding
LNM86_RS11860	COG0351	phosphomethylpyrimidine kinase
LNM86_RS11870	COG1686	Belongs to the peptidase S11 family
LNM86_RS11875	COG0523	cobalamin synthesis protein
LNM86_RS11885	COG3034	peptidoglycan biosynthetic process
LNM86_RS11890	COG0825	malonyl-CoA metabolic process
LNM86_RS11900	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LNM86_RS11905	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LNM86_RS11915	COG3895	Periplasmic Protein
LNM86_RS11920	COG1320	monovalent cation:proton antiporter activity
LNM86_RS11925	COG2212	antiporter activity
LNM86_RS11935	COG0651	ATP synthesis coupled electron transport
LNM86_RS11940	COG1006	Multisubunit Na H antiporter MnhC subunit
LNM86_RS11945	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LNM86_RS11945	COG2111	Na H antiporter
LNM86_RS11955	COG0019	diaminopimelate decarboxylase activity
LNM86_RS11990	COG0045	succinate-CoA ligase (ADP-forming) activity
LNM86_RS11995	COG0039	L-malate dehydrogenase activity
LNM86_RS12000	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LNM86_RS12010	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LNM86_RS12015	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LNM86_RS12020	COG0552	protein localization to endoplasmic reticulum
LNM86_RS12030	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LNM86_RS12050	COG0357	Ribosomal RNA small subunit methyltransferase G
LNM86_RS12055	COG0445	tRNA wobble uridine modification
LNM86_RS12060	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LNM86_RS12065	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LNM86_RS12070	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LNM86_RS12075	COG0424	maF-like protein
LNM86_RS12080	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LNM86_RS12085	COG0237	dephospho-CoA kinase activity
LNM86_RS12090	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
LNM86_RS12095	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LNM86_RS12095	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LNM86_RS12105	COG0670	Belongs to the BI1 family
LNM86_RS12110	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LNM86_RS12115	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LNM86_RS12120	COG0116	Belongs to the methyltransferase superfamily
LNM86_RS12120	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LNM86_RS12130	COG0776	regulation of translation
LNM86_RS12145	COG1137	ATPase activity
LNM86_RS12155	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LNM86_RS12165	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LNM86_RS12175	COG0137	argininosuccinate synthase activity
LNM86_RS12185	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LNM86_RS12205	COG0802	atpase or kinase
LNM86_RS12210	COG2205	protein histidine kinase activity
LNM86_RS12215	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LNM86_RS12225	COG0702	epimerase
LNM86_RS12230	COG0285	dihydrofolate synthase activity
LNM86_RS12235	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LNM86_RS12255	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LNM86_RS12260	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LNM86_RS12265	COG2226	methyltransferase
LNM86_RS12275	COG0582	viral genome integration into host DNA
LNM86_RS12310	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
LNM86_RS12335	COG0729	surface antigen
LNM86_RS12350	COG1132	(ABC) transporter
LNM86_RS12355	COG1132	(ABC) transporter
LNM86_RS12360	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LNM86_RS12380	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LNM86_RS12385	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LNM86_RS12390	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LNM86_RS12395	COG1420	regulation of RNA biosynthetic process
LNM86_RS12400	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LNM86_RS12420	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
LNM86_RS12420	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LNM86_RS12430	COG2205	protein histidine kinase activity
LNM86_RS12435	COG0745	RESPONSE REGULATOR receiver
LNM86_RS12440	COG1652	LysM domain
LNM86_RS12450	COG0443	Heat shock 70 kDa protein
LNM86_RS12455	COG0484	heat shock protein binding
LNM86_RS12465	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LNM86_RS12485	COG0481	GTPase activity
LNM86_RS12490	COG2171	N-acyltransferase activity
LNM86_RS12500	COG0101	tRNA pseudouridine synthase activity
LNM86_RS12505	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LNM86_RS12510	COG0242	peptide deformylase activity
LNM86_RS12545	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LNM86_RS12550	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LNM86_RS12555	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LNM86_RS12560	COG0072	phenylalanine-tRNA ligase activity
LNM86_RS12560	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LNM86_RS12570	COG1121	(ABC) transporter
LNM86_RS12575	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LNM86_RS12580	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LNM86_RS12585	COG2832	Protein of unknown function (DUF454)
LNM86_RS12590	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LNM86_RS12595	COG3459	Glycosyltransferase 36 associated
LNM86_RS12600	COG0539	negative regulation of cytoplasmic translation
LNM86_RS12605	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LNM86_RS12610	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LNM86_RS12625	COG0129	dihydroxy-acid dehydratase activity
LNM86_RS12630	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LNM86_RS12635	COG0280	phosphate acetyltransferase
LNM86_RS12635	COG0281	malic enzyme
LNM86_RS12640	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LNM86_RS12645	COG3030	protein affecting phage T7 exclusion by the F plasmid
LNM86_RS12660	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
LNM86_RS12670	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LNM86_RS12690	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LNM86_RS12700	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LNM86_RS12705	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LNM86_RS12710	COG4133	protoheme IX ABC transporter activity
LNM86_RS12715	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LNM86_RS12720	COG0268	Binds directly to 16S ribosomal RNA
LNM86_RS12725	COG3958	Transketolase
LNM86_RS12745	COG0431	NADPH-dependent FMN reductase