locus-tag	class	description
MF1_RS00005	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
MF1_RS00010	ENOG4108UHJ	MAF-like protein
MF1_RS00015	ENOG4105E2X	shikimate dehydrogenase
MF1_RS00020	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
MF1_RS00030	ENOG4105C2M	dna polymerase I
MF1_RS00040	ENOG4105HFZ	Membrane
MF1_RS00045	ENOG4105M02	This protein specifically catalyzes the removal of signal peptides from prolipoproteins (By similarity)
MF1_RS00065	ENOG41080YA	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
MF1_RS00075	ENOG4105RF0	OstA family
MF1_RS00080	ENOG4108IUZ	ABC transporter
MF1_RS00085	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
MF1_RS00095	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
MF1_RS00115	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
MF1_RS00125	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
MF1_RS00135	ENOG4105K8N	protein family UPF0079, ATPase
MF1_RS00140	ENOG4105I8F	Histidine kinase
MF1_RS00145	ENOG4105C3E	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (By similarity)
MF1_RS00150	ENOG4105CGD	Nad-dependent epimerase dehydratase
MF1_RS00155	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
MF1_RS00160	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
MF1_RS00165	ENOG4105CJS	Phosphopantothenoylcysteine decarboxylase
MF1_RS00170	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
MF1_RS00175	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
MF1_RS00180	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MF1_RS00190	ENOG4105C0P	Mg chelatase subunit ChlI
MF1_RS00210	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
MF1_RS00225	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
MF1_RS00230	ENOG4105CSA	Coproporphyrinogen iii oxidase
MF1_RS00235	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
MF1_RS00240	ENOG4105CI8	Negative regulator of class I heat shock genes (grpE- dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons (By similarity)
MF1_RS00245	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
MF1_RS00260	ENOG4108EQA	pts system
MF1_RS00270	ENOG4105EB3	Histidine kinase
MF1_RS00275	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
MF1_RS00280	ENOG4109066	lysm domain bon superfamily protein
MF1_RS00290	ENOG4105CFG	Acts as a chaperone (By similarity)
MF1_RS00295	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
MF1_RS00300	ENOG4105CAS	nag kinase
MF1_RS00305	ENOG410631K	Membrane
MF1_RS00310	ENOG4105C4S	Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back- translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner (By similarity)
MF1_RS00315	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
MF1_RS00325	ENOG4105DI7	Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs (By similarity)
MF1_RS00330	ENOG4105CAE	Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (By similarity)
MF1_RS00335	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
MF1_RS00340	ENOG4105CGY	Dna recombination protein
MF1_RS00365	ENOG41082BR	50S ribosomal protein L35
MF1_RS00370	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
MF1_RS00375	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
MF1_RS00380	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
MF1_RS00390	ENOG4105DIK	(ABC) transporter
MF1_RS00395	ENOG4105CC5	ABC transporter
MF1_RS00400	ENOG4105CC5	ABC transporter
MF1_RS00405	ENOG4105WD1	Membrane
MF1_RS00410	ENOG4107RH7	Nicotinate phosphoribosyltransferase
MF1_RS00415	ENOG4105E2V	Glycosyltransferase 36
MF1_RS00420	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
MF1_RS00425	ENOG4105CAT	Cytidine monophosphate kinase
MF1_RS00430	ENOG4105CMY	5-enolpyruvylshikimate-3-phosphate synthase
MF1_RS00450	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
MF1_RS00455	ENOG4105C6K	Malic enzyme
MF1_RS00460	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
MF1_RS00465	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
MF1_RS00480	ENOG4105F4C	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress (By similarity)
MF1_RS00490	ENOG4105C8Y	Acetylornithine aminotransferase
MF1_RS00510	ENOG41060IM	Heme exporter protein
MF1_RS00515	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
MF1_RS00520	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
MF1_RS00525	ENOG4107QM5	aconitate hydratase
MF1_RS00530	ENOG4105KQV	Binds directly to 16S ribosomal RNA (By similarity)
MF1_RS00535	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
MF1_RS00540	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)
MF1_RS00550	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
MF1_RS00555	ENOG4105E2S	oxidase) subunit II
MF1_RS00560	ENOG4105BZ9	Cytochrome C oxidase, subunit I
MF1_RS00565	ENOG4105CCU	oxidase (Subunit III)
MF1_RS00570	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
MF1_RS00575	ENOG4105CSF	NADPH-dependent glycerol-3-phosphate dehydrogenase
MF1_RS00580	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
MF1_RS00590	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
MF1_RS00605	ENOG4105K5G	30S ribosomal protein S21
MF1_RS00625	ENOG4105BZS	acriflavin resistance protein
MF1_RS00630	ENOG4107QP8	phosphohexose isomerase
MF1_RS00640	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
MF1_RS00645	ENOG4105K46	50S ribosomal protein l27
MF1_RS00650	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
MF1_RS00710	ENOG4105F7M	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit (By similarity)
MF1_RS00715	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
MF1_RS00720	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
MF1_RS00725	ENOG4105C2S	Catalyzes the NADPH dependent reduction of L-gamma- glutamyl 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate (By similarity)
MF1_RS00730	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
MF1_RS00750	ENOG4105CN1	protease
MF1_RS00755	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
MF1_RS00760	ENOG4105PS1	invasion associated locus B
MF1_RS00770	ENOG410856B	UPF0235 protein
MF1_RS00775	ENOG4105F0N	pyrophosphate phospho-hydrolase
MF1_RS00780	ENOG4105CI3	gtp-binding protein typa
MF1_RS00785	ENOG4105CJW	magnesium transporter
MF1_RS00800	ENOG4105CVE	Lytic murein transglycosylase
MF1_RS00810	ENOG4105C2X	Arabinose 5-phosphate isomerase
MF1_RS00825	ENOG4107RZC	phospholipase d
MF1_RS00835	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MF1_RS00840	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MF1_RS00845	ENOG4107T6V	glycerophosphoryl diester phosphodiesterase
MF1_RS00850	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
MF1_RS00855	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
MF1_RS00870	ENOG4105DSE	periplasmic solute binding protein
MF1_RS00875	ENOG4105CC5	ABC transporter
MF1_RS00880	ENOG4105DIK	(ABC) transporter
MF1_RS00890	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
MF1_RS00895	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
MF1_RS00905	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
MF1_RS00910	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
MF1_RS00920	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
MF1_RS00925	ENOG4105EIN	peptidylprolyl cis-trans isomerase
MF1_RS00930	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
MF1_RS00935	ENOG4105M6F	mutator MutT protein
MF1_RS00945	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
MF1_RS00950	ENOG4105CS9	pantothenic acid kinase
MF1_RS00955	ENOG4105HDK	L-asparaginase
MF1_RS00960	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
MF1_RS00965	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
MF1_RS00970	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
MF1_RS00975	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
MF1_RS00980	ENOG4105K77	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome (By similarity)
MF1_RS00995	ENOG4105D0T	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs (By similarity)
MF1_RS01000	ENOG4107ZGG	Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Essential for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA (By similarity)
MF1_RS01005	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
MF1_RS01015	ENOG4105CHV	Transcription elongation factor NusA
MF1_RS01020	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
MF1_RS01025	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
MF1_RS01030	ENOG4105CPH	Catalyzes the formation of S-adenosylmethionine from methionine and ATP
MF1_RS01035	ENOG4108WRK	Transcriptional regulator
MF1_RS01040	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
MF1_RS01045	ENOG4108JU5	Magnesium and cobalt efflux protein
MF1_RS01050	ENOG4105KGE	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA (By similarity)
MF1_RS01055	ENOG4105C9A	Phoh family
MF1_RS01060	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
MF1_RS01070	ENOG41072GX	Peptidase M22 Glycoprotease
MF1_RS01080	ENOG4105F3K	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO (By similarity)
MF1_RS01085	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
MF1_RS01090	ENOG4107QMP	dna polymerase iii subunits gamma and tau
MF1_RS01110	ENOG4105CET	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria (By similarity)
MF1_RS01115	ENOG4105G9V	cytochrome C
MF1_RS01135	ENOG4105D7Z	glutathione synthase
MF1_RS01145	ENOG4105C8U	phosphate abc transporter
MF1_RS01155	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
MF1_RS01160	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
MF1_RS01170	ENOG4105C88	aminopeptidase
MF1_RS01175	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
MF1_RS01195	ENOG4105JVC	membrAne
MF1_RS01200	ENOG4108JBU	Outer membrane protein Omp31
MF1_RS01205	ENOG4105JVC	membrAne
MF1_RS01210	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
MF1_RS01220	ENOG4108Z6B	deaminase
MF1_RS01230	ENOG4106H78	methyltransferase
MF1_RS01240	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
MF1_RS01245	ENOG4107TK4	histidinol-phosphate phosphatase
MF1_RS01255	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
MF1_RS01260	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
MF1_RS01270	ENOG4105DC6	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex (By similarity)
MF1_RS01275	ENOG4105DHP	deoxycytidine triphosphate deaminase
MF1_RS01280	ENOG4105DMF	Dehydrogenase
MF1_RS01315	ENOG4105C85	amino acid
MF1_RS01320	ENOG4108JJB	ABC transporter
MF1_RS01325	ENOG4105EK6	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates (By similarity)
MF1_RS01330	ENOG4107ZYJ	bioY protein
MF1_RS01355	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
MF1_RS01365	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MF1_RS01390	ENOG4105BZU	Histidine kinase
MF1_RS01395	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
MF1_RS01400	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
MF1_RS01415	ENOG4105CJP	fad dependent oxidoreductase
MF1_RS01420	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
MF1_RS01425	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
MF1_RS01435	ENOG4105CN0	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (By similarity)
MF1_RS01455	ENOG4108ETY	sodium dicarboxylate symporter
MF1_RS01465	ENOG41081UC	Inherit from COG: Competence protein
MF1_RS01470	ENOG4105VW4	glutaredoxin 3
MF1_RS01475	ENOG4108HWB	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
MF1_RS01480	ENOG4105CFH	Aspartokinase
MF1_RS01485	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
MF1_RS01505	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
MF1_RS01515	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
MF1_RS01520	ENOG4105VD1	ATP synthase subunit C
MF1_RS01525	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
MF1_RS01530	ENOG4105S06	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
MF1_RS01535	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
MF1_RS01550	ENOG4105EAH	synthase
MF1_RS01565	ENOG4105CTR	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol (By similarity)
MF1_RS01575	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
MF1_RS01595	ENOG4105C3G	gtp-binding protein
MF1_RS01600	ENOG4108PXI	ErfK YbiS YcfS YnhG
MF1_RS01605	ENOG4108ZPD	The natural substrate for this enzyme may be peptidyl- tRNAs which drop off the ribosome during protein synthesis (By similarity)
MF1_RS01610	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
MF1_RS01625	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
MF1_RS01635	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
MF1_RS01655	ENOG4105E0F	Histidine kinase
MF1_RS01660	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
MF1_RS01665	ENOG4105C5X	domain protein
MF1_RS01675	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
MF1_RS01685	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
MF1_RS01695	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
MF1_RS01700	ENOG4105C3M	thioredoxin reductase
MF1_RS01705	ENOG4105CBN	LysR family transcriptional regulator
MF1_RS01710	ENOG4105CHM	Aminotransferase
MF1_RS01730	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
MF1_RS01735	ENOG4105VEI	Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4- hydroxybenzoate (4HB) for the ubiquinone pathway (By similarity)
MF1_RS01750	ENOG4105CUY	Mechanosensitive ion channel
MF1_RS01755	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
MF1_RS01760	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
MF1_RS01770	ENOG4105MPN	Membrane
MF1_RS01810	ENOG4108RWI	nicotinamidase
MF1_RS01835	ENOG4105E4C	Lytic transglycosylase catalytic
MF1_RS01845	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
MF1_RS01870	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
MF1_RS01875	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
MF1_RS01885	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
MF1_RS01890	ENOG4105DFU	Cell wall formation (By similarity)
MF1_RS01895	ENOG4105D4A	Cell wall formation (By similarity)
MF1_RS01900	ENOG4105CPF	Cell wall formation (By similarity)
MF1_RS01905	ENOG4108UFP	Essential cell division protein (By similarity)
MF1_RS01910	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
MF1_RS01915	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
MF1_RS01920	ENOG4105C7C	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
MF1_RS01925	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MF1_RS01935	ENOG4105C77	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA (By similarity)
MF1_RS01940	ENOG4105DC7	peptidase M24
MF1_RS01990	ENOG4105CSH	Transporter
MF1_RS01995	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
MF1_RS02015	ENOG4105C0H	protease
MF1_RS02020	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
MF1_RS02030	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
MF1_RS02035	ENOG4105CSZ	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate (By similarity)
MF1_RS02040	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
MF1_RS02045	ENOG4105C85	amino acid
MF1_RS02060	ENOG4105EE5	Membrane protein terC
MF1_RS02070	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
MF1_RS02085	ENOG4105EGS	Mechanosensitive ion channel
MF1_RS02095	ENOG4105JVC	membrAne
MF1_RS02120	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
MF1_RS02135	ENOG4105CA4	amino acids such as threonine, to avoid such errors, it has a posttransfer editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (By similarity)
MF1_RS02140	ENOG4105CDA	abc transporter atp-binding protein
MF1_RS02145	ENOG4105DRP	amino acid AbC transporter
MF1_RS02150	ENOG4105EAD	ABC transporter
MF1_RS02155	ENOG4107RP9	extracellular solute-binding protein, family 3
MF1_RS02165	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
MF1_RS02170	ENOG4108UHY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA (By similarity)
MF1_RS02175	ENOG4105CEJ	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome (By similarity)
MF1_RS02180	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
MF1_RS02190	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
MF1_RS02195	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
MF1_RS02200	ENOG41080KG	One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome (By similarity)
MF1_RS02205	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
MF1_RS02210	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
MF1_RS02215	ENOG4105KAP	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome (By similarity)
MF1_RS02220	ENOG4105CKE	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation (By similarity)
MF1_RS02225	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
MF1_RS02230	ENOG41083MP	50s ribosomal protein l29
MF1_RS02235	ENOG4105K87	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal
MF1_RS02240	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
MF1_RS02245	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
MF1_RS02250	ENOG4105CW6	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
MF1_RS02255	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
MF1_RS02260	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
MF1_RS02265	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
MF1_RS02270	ENOG4105K4C	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance (By similarity)
MF1_RS02275	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
MF1_RS02280	ENOG41084HQ	50S ribosomal protein L30
MF1_RS02285	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
MF1_RS02290	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
MF1_RS02295	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
MF1_RS02300	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
MF1_RS02305	ENOG4108UHH	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome (By similarity)
MF1_RS02310	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MF1_RS02315	ENOG4108ZT0	50S ribosomal protein l17
MF1_RS02320	ENOG4105C0H	protease
MF1_RS02325	ENOG4105D1H	recombination factor protein RarA
MF1_RS02330	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
MF1_RS02335	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
MF1_RS02340	ENOG4105BZ1	(ABC) transporter
MF1_RS02345	ENOG4105EI2	Pseudouridine synthase
MF1_RS02360	ENOG4105C5F	glutamine synthetase
MF1_RS02365	ENOG4108YZA	Nitrogen regulatory protein pii
MF1_RS02375	ENOG4108UUM	single-stranded DNA-binding protein
MF1_RS02385	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
MF1_RS02395	ENOG4108R5K	PPIases accelerate the folding of proteins (By similarity)
MF1_RS02430	ENOG4105CBT	Fructose-1,6-bisphosphatase
MF1_RS02435	ENOG4105CM2	brancheD-chain amino acid aminotransferase
MF1_RS02450	ENOG4105C75	arginyL-tRNA synthetase
MF1_RS02455	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
MF1_RS02460	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
MF1_RS02470	ENOG4107QIV	Cytochrome c biogenesis protein
MF1_RS02475	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
MF1_RS02480	ENOG4105C46	Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (By similarity)
MF1_RS02490	ENOG4105C0B	DNA polymerase III (alpha subunit)
MF1_RS02495	ENOG4105MSY	salicylate hydroxylase
MF1_RS02505	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
MF1_RS02510	ENOG4105C9X	ppx gppa phosphatase
MF1_RS02515	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
MF1_RS02520	ENOG4105C9M	aspartyl-trna synthetase
MF1_RS02525	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MF1_RS02530	ENOG4105C2C	drug resistance transporter, Bcr CflA
MF1_RS02545	ENOG4108JIU	phosphoribosylformylglycinamidine synthase ii
MF1_RS02550	ENOG4105D21	Phosphoribosylformylglycinamidine synthase I
MF1_RS02555	ENOG410839H	phosphoribosylformylglycinamidine synthase
MF1_RS02560	ENOG4107QPR	SAICAR synthetase
MF1_RS02570	ENOG4105C83	adenylosuccinate lyase
MF1_RS02575	ENOG4105DJV	ribulose-phosphate 3-epimerase
MF1_RS02585	ENOG4108V7X	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
MF1_RS02600	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
MF1_RS02605	ENOG4105CXB	phosphoribosylaminoimidazole synthetase
MF1_RS02610	ENOG4105C02	permease
MF1_RS02655	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
MF1_RS02660	ENOG4105CHT	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
MF1_RS02670	ENOG4106ECF	Uncharacterized protein conserved in bacteria (DUF2155)
MF1_RS02680	ENOG4105C2N	RNA methyltransferase TrmH family group 3
MF1_RS02700	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
MF1_RS02720	ENOG4108UIK	This protein binds directly to 23S ribosomal RNA (By similarity)
MF1_RS02725	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
MF1_RS02730	ENOG4108VZM	50s ribosomal protein L10
MF1_RS02735	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
MF1_RS02740	ENOG4108IIJ	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MF1_RS02745	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
MF1_RS02760	ENOG4105EJQ	L-serine dehydratase
MF1_RS02770	ENOG4105DZ1	carboxypeptidase
MF1_RS02775	ENOG4105KAE	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation (By similarity)
MF1_RS02785	ENOG4105K59	histidine triad (HIT) protein
MF1_RS02800	ENOG4105CE9	30S ribosomal protein S2
MF1_RS02805	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
MF1_RS02810	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
MF1_RS02815	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
MF1_RS02820	ENOG4105KNE	Phosphatidate cytidylyltransferase
MF1_RS02825	ENOG4105DZP	Membrane-associated zinc metalloprotease
MF1_RS02830	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
MF1_RS02835	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
MF1_RS02840	ENOG4108YXN	Involved in unsaturated fatty acids biosynthesis. Catalyzes the dehydration of short chain beta-hydroxyacyl-ACPs and long chain saturated and unsaturated beta-hydroxyacyl-ACPs (By similarity)
MF1_RS02845	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
MF1_RS02855	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
MF1_RS02860	ENOG4105CDA	abc transporter atp-binding protein
MF1_RS02870	ENOG4105GBT	ABC transporter
MF1_RS02875	ENOG4105E89	ABC transporter
MF1_RS02880	ENOG4105BZN	citrate synthase
MF1_RS02885	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
MF1_RS02895	ENOG4105E66	phosphoriboisomerase A
MF1_RS02910	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
MF1_RS02915	ENOG4105C4K	Nad synthetase
MF1_RS02920	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
MF1_RS02925	ENOG4105C1J	atp-dependent rna helicase
MF1_RS02940	ENOG4105C84	Histidine ammonia-lyase
MF1_RS02950	ENOG4105C85	amino acid
MF1_RS02960	ENOG4108UXN	response regulator
MF1_RS02965	ENOG4108UJD	30S ribosomal protein S9
MF1_RS02970	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
MF1_RS02975	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
MF1_RS02980	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
MF1_RS02985	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
MF1_RS03030	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
MF1_RS03035	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
MF1_RS03050	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
MF1_RS03070	ENOG4108RG0	uracil-dna glycosylase
MF1_RS03080	ENOG4105W0E	50S ribosomal protein L33
MF1_RS03085	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
MF1_RS03100	ENOG4105C79	DNA protecting protein DprA
MF1_RS03105	ENOG4105K7Z	Catalyzes the transfer of an acyl group from acyl- phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP (By similarity)
MF1_RS03110	ENOG4105CD3	dihydroorotase
MF1_RS03115	ENOG4105CXT	aspartate transcarbamylase
MF1_RS03125	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
MF1_RS03130	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
MF1_RS03135	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
MF1_RS03140	ENOG4108IV0	ABC, transporter
MF1_RS03145	ENOG4105C0Z	ABC transporter
MF1_RS03150	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
MF1_RS03155	ENOG4105C32	Amino acid ABC transporter (Permease)
MF1_RS03165	ENOG4105VEQ	Cold shock protein
MF1_RS03185	ENOG4105W5Q	DNA repair protein (RadC
MF1_RS03190	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
MF1_RS03195	ENOG4105PW4	Sugar fermentation stimulation protein homolog
MF1_RS03205	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
MF1_RS03210	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
MF1_RS03225	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
MF1_RS03240	ENOG4105DZ1	carboxypeptidase
MF1_RS03245	ENOG4108ZMD	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis (By similarity)
MF1_RS03250	ENOG4107QRG	dna polymerase iii
MF1_RS03255	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
MF1_RS03260	ENOG4105F8V	Hydrolase, tatD family
MF1_RS03265	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
MF1_RS03275	ENOG4105VE1	Phosphatidylcholine synthase
MF1_RS03280	ENOG4105EAK	ubiquinone biosynthesis hydroxylase, ubiH ubiF VisC COQ6 family
MF1_RS03305	ENOG4105JRK	feS assembly protein SufD
MF1_RS03310	ENOG4105C3K	feS assembly ATPase SufC
MF1_RS03325	ENOG4105DHZ	alpha beta
MF1_RS03330	ENOG4105DA0	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr) (By similarity)
MF1_RS03335	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
MF1_RS03350	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
MF1_RS03355	ENOG4105C03	ribonuclease
MF1_RS03375	ENOG4107NKQ	Flavinator of succinate dehydrogenase
MF1_RS03380	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
MF1_RS03390	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
MF1_RS03405	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MF1_RS03410	ENOG4105C8S	subunit m
MF1_RS03415	ENOG4105D65	subunit l
MF1_RS03420	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MF1_RS03425	ENOG4105DF2	NADH dehydrogenase subunit j
MF1_RS03430	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MF1_RS03435	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
MF1_RS03440	ENOG4107R0R	NADH dehydrogenase subunit g
MF1_RS03445	ENOG4107QIZ	NADH dehydrogenase
MF1_RS03450	ENOG4105GKE	subunit e
MF1_RS03455	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MF1_RS03460	ENOG4105CYU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MF1_RS03465	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
MF1_RS03470	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
MF1_RS03510	ENOG4105EUJ	GTP cyclohydrolase i
MF1_RS03520	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
MF1_RS03525	ENOG4105C22	threonyL-tRNA synthetase
MF1_RS03530	ENOG4105WJX	transcriptional regulator MERR family
MF1_RS03535	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
MF1_RS03540	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
MF1_RS03545	ENOG4105C6B	Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl- acyl-carrier-protein (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA (By similarity)
MF1_RS03560	ENOG4107XZX	Involved in the transcription termination process (By similarity)
MF1_RS03565	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
MF1_RS03575	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
MF1_RS03580	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
MF1_RS03585	ENOG4105C65	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (By similarity)
MF1_RS03590	ENOG4105C0N	N-acetylglutamate semialdehyde dehydrogenase
MF1_RS03595	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
MF1_RS03605	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
MF1_RS03610	ENOG4105KW8	RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs (By similarity)
MF1_RS03620	ENOG4105C6K	Malic enzyme
MF1_RS03625	ENOG4105J3Q	acyl carrier protein
MF1_RS03630	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
MF1_RS03635	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
MF1_RS03665	ENOG4108ZNX	Heat shock protein
MF1_RS03750	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
MF1_RS03755	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
MF1_RS03765	ENOG4105C1A	potassium transporter peripheral membrane
MF1_RS03770	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
MF1_RS03775	ENOG4105ES5	Histidine kinase
MF1_RS03780	ENOG4105KPV	Transcriptional regulator
MF1_RS03785	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
MF1_RS03790	ENOG4105CEV	competence damage-inducible protein
MF1_RS03795	ENOG4108Z1B	Cyclase dehydrase
MF1_RS03800	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
MF1_RS03805	ENOG4107QN2	dihydrolipoyl dehydrogenase
MF1_RS03810	ENOG4105C7S	Dehydrogenase
MF1_RS03815	ENOG4105CPP	Dehydrogenase, E1 component
MF1_RS03820	ENOG4108JYK	Dehydrogenase
MF1_RS03835	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
MF1_RS03840	ENOG4105CXR	Phospho-2-dehydro-3-deoxyoctonate aldolase
MF1_RS03845	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
MF1_RS03850	ENOG4107EJC	Preprotein translocase subunit SecG
MF1_RS03855	ENOG4105CP7	Triose-phosphate isomerase
MF1_RS03865	ENOG4105FE1	phytoene synthase
MF1_RS03880	ENOG4108K5P	(LipO)protein
MF1_RS03885	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
MF1_RS03890	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
MF1_RS03895	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
MF1_RS03915	ENOG4105D6S	protein involved in catabolism of external DNA
MF1_RS03920	ENOG4105CII	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision (By similarity)
MF1_RS03930	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
MF1_RS03940	ENOG4105CSH	Transporter
MF1_RS03965	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
MF1_RS03975	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
MF1_RS03980	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
MF1_RS03985	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
MF1_RS03990	ENOG4105HHA	aminodeoxychorismate lyase
MF1_RS03995	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
MF1_RS04000	ENOG4105VNB	Carrier of the growing fatty acid chain in fatty acid biosynthesis (By similarity)
MF1_RS04010	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
MF1_RS04015	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
MF1_RS04020	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
MF1_RS04025	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
MF1_RS04035	ENOG4105K9Q	Binds to the 23S rRNA (By similarity)
MF1_RS04040	ENOG4105CDU	Replicative dna helicase
MF1_RS04055	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
MF1_RS04060	ENOG4105UBK	short-chain dehydrogenase reductase
MF1_RS04065	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
MF1_RS04070	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
MF1_RS04075	ENOG4108JJ7	ABC transporter
MF1_RS04085	ENOG4105C8N	cysteinyl-tRNA synthetase
MF1_RS04095	ENOG4105CD3	dihydroorotase
MF1_RS04100	ENOG4106XY2	Folate-binding protein involved in regulating the level of ATP-DnaA and in the modification of some tRNAs. It is probably a key factor in regulatory networks that act via tRNA modification, such as initiation of chromosomal replication (By similarity)
MF1_RS04105	ENOG4108R7K	Metal Dependent Phosphohydrolase
MF1_RS04110	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
MF1_RS04115	ENOG4108IAA	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
MF1_RS04120	ENOG4107UIS	Involved in DNA repair and RecF pathway recombination (By similarity)
MF1_RS04130	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
MF1_RS04140	ENOG4105KJV	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
MF1_RS04150	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
MF1_RS04160	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
MF1_RS04165	ENOG4105E50	uracil-dna glycosylase
MF1_RS04170	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
MF1_RS04175	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
MF1_RS04190	ENOG4107ENK	receptor
MF1_RS04195	ENOG4106QJH	hemin transport protein
MF1_RS04200	ENOG4107R4I	Periplasmic binding protein
MF1_RS04205	ENOG4105EHG	Permease protein
MF1_RS04210	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
MF1_RS04215	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
MF1_RS04230	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
MF1_RS04240	ENOG4105DWF	phosphomethylpyrimidine kinase
MF1_RS04250	ENOG4105CD8	aminopeptidase N
MF1_RS04255	ENOG4105BZU	Histidine kinase
MF1_RS04260	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
MF1_RS04265	ENOG4105JVC	membrAne
MF1_RS04270	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
MF1_RS04275	ENOG4105BZU	Histidine kinase
MF1_RS04280	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MF1_RS04285	ENOG4105C0H	protease
MF1_RS04290	ENOG4105KWW	Biogenesis protein
MF1_RS04295	ENOG4105DA4	cytochrome c-type biogenesis protein
MF1_RS04300	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
MF1_RS04310	ENOG4105BZU	Histidine kinase
MF1_RS04315	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
MF1_RS04325	ENOG4108JQC	penicillin-binding protein 1A
MF1_RS04355	ENOG41083J0	(ABC) transporter
MF1_RS04365	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
MF1_RS04375	ENOG4108YXV	Transcriptional regulator
MF1_RS04380	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
MF1_RS04400	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
MF1_RS04415	ENOG4105CEN	a g-specific adenine glycosylase
MF1_RS04420	ENOG4105CEC	DNA methylase N-4 N-6
MF1_RS04425	ENOG4107URF	beta-phospho-glucomutase
MF1_RS04455	ENOG4105C1V	Peptidase, M16
MF1_RS04465	ENOG4108UJU	UPF0301 protein
MF1_RS04470	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
MF1_RS04480	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
MF1_RS04485	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
MF1_RS04495	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
MF1_RS04500	ENOG4107QS4	23S rRNA
MF1_RS04505	ENOG4107QS4	23S rRNA
MF1_RS04510	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
MF1_RS04520	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
MF1_RS04525	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
MF1_RS04530	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
MF1_RS04535	ENOG4105D10	5-enolpyruvylshikimate-3-phosphate phospholyase
MF1_RS04540	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
MF1_RS04545	ENOG4105DVC	DnaJ domain protein
MF1_RS04550	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
MF1_RS04560	ENOG4105C12	Phosphoribosylglycinamide synthetase
MF1_RS04570	ENOG4105CQB	FAD linked oxidase domain protein
MF1_RS04575	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
MF1_RS04580	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
MF1_RS04590	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
MF1_RS04595	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
MF1_RS04600	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
MF1_RS04635	ENOG4105CCJ	Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34 (By similarity)
MF1_RS04650	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
MF1_RS04670	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
MF1_RS04690	ENOG4108JQ7	(ABC) transporter
MF1_RS04700	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
MF1_RS04705	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
MF1_RS04710	ENOG4105DEF	Extracellular solute-binding protein, family 5
MF1_RS04715	ENOG4105DEF	Extracellular solute-binding protein, family 5
MF1_RS04725	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
MF1_RS04730	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
MF1_RS04740	ENOG4108VCT	Sulfite exporter TauE/SafE
MF1_RS04750	ENOG4105BZJ	Electron transfer flavoprotein
MF1_RS04755	ENOG4105C10	Electron transfer flavoprotein
MF1_RS04760	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
MF1_RS04775	ENOG41082FP	UPF0102 protein
MF1_RS04780	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
MF1_RS04790	ENOG4105VG0	50S ribosomal protein l34
MF1_RS04795	ENOG4105KK3	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
MF1_RS04805	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
MF1_RS04815	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
MF1_RS04820	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
MF1_RS04845	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
MF1_RS04850	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
MF1_RS04890	ENOG4105MYN	Zinc uptake regulation protein
MF1_RS04915	ENOG4105C72	UPF0176 protein
MF1_RS04925	ENOG4105DP0	ferredoxin-NADP reductase
MF1_RS04935	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
MF1_RS04940	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
MF1_RS04945	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
MF1_RS04955	ENOG4105W49	UPF0434 protein
MF1_RS04960	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
MF1_RS05035	ENOG4105CM4	permease protein
MF1_RS05040	ENOG4108IPW	abc transporter atp-binding protein
MF1_RS05095	ENOG4105DTN	riboflavin biosynthesis protein ribF
MF1_RS05150	ENOG4108V42	Type IV secretion system protein VirB8
MF1_RS05160	ENOG4105CMA	conjugation trbi family protein
MF1_RS05165	ENOG4108EHY	type IV secretion system
MF1_RS05175	ENOG4105E80	TraG TraD family protein
MF1_RS05185	ENOG4105MZU	cell filamentation protein
MF1_RS05205	ENOG4105CJR	Integral membrane protein (MviN
MF1_RS05210	ENOG4105C31	Tryptophanyl-tRNA synthetase
MF1_RS05220	ENOG41083MR	nifu domain-containing protein
MF1_RS05230	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
MF1_RS05235	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
MF1_RS05240	ENOG4105C9Q	fumarate hydratase class II
MF1_RS05245	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
MF1_RS05265	ENOG4105CUT	histidyl-tRNA synthetase
MF1_RS05270	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
MF1_RS05310	ENOG4105DR5	peptidase
MF1_RS05320	ENOG4105RAK	Histidine kinase
MF1_RS05335	ENOG41074H6	response regulator
MF1_RS05340	ENOG4105BZU	Histidine kinase
MF1_RS05435	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
MF1_RS05445	ENOG4108Z03	MAF-like protein
MF1_RS05450	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
MF1_RS05465	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
MF1_RS05475	ENOG41080I0	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein (By similarity)
MF1_RS05490	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
MF1_RS05495	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
MF1_RS05500	ENOG4105YK5	50S ribosomal protein L36
MF1_RS05505	ENOG4105M0T	TPR Repeat-Containing Protein
MF1_RS05535	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
MF1_RS05630	ENOG4108UM1	dedA family
MF1_RS05650	ENOG4108Z1K	This enzyme is involved in nucleotide metabolism it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA (By similarity)
MF1_RS05660	ENOG4108ZZF	transport protein (ExbD)
MF1_RS05680	ENOG4107QJF	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (By similarity)
MF1_RS05685	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
MF1_RS05690	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
MF1_RS05715	ENOG4105CDY	transcriptional regulatory protein
MF1_RS05730	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
MF1_RS05740	ENOG4105SG9	biopolymer transport protein, ExbD
MF1_RS05745	ENOG4105E02	MotA TolQ exbB proton channel
MF1_RS05750	ENOG4107YD3	Thioesterase
MF1_RS05755	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
MF1_RS05760	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
MF1_RS05765	ENOG4105NHU	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group (By similarity)
MF1_RS05795	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
MF1_RS05800	ENOG4105ECY	inositol monophosphatase
MF1_RS05805	ENOG4105BZ1	(ABC) transporter
MF1_RS05810	ENOG41082FS	50S ribosomal protein L31
MF1_RS05815	ENOG4107R1Y	fructose-bisphosphate aldolase
MF1_RS05820	ENOG4105BZA	Phosphoglycerate kinase
MF1_RS05860	ENOG4105CA9	Pyruvate kinase
MF1_RS05870	ENOG4105Y2X	UPF0335 protein
MF1_RS05875	ENOG4105C5H	ABC transporter
MF1_RS05890	ENOG4105ERG	peptidase m48, ste24p
MF1_RS05905	ENOG4108Z4U	Ferredoxin
MF1_RS05915	ENOG41082R8	50S ribosomal protein l32
MF1_RS05920	ENOG4105CTB	Polyprenyl synthetase
MF1_RS05925	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
MF1_RS05935	ENOG4105CW7	secretion protein, HlyD family
MF1_RS05945	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
MF1_RS05950	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
MF1_RS05955	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
MF1_RS05960	ENOG4105CDG	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit (By similarity)
MF1_RS05965	ENOG4105E3N	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
MF1_RS05975	ENOG4105C25	Primosomal protein n'
MF1_RS05980	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
MF1_RS05990	ENOG4105C8T	Leucyl-tRNA synthetase
MF1_RS05995	ENOG4105DFA	alanine racemase domain protein
MF1_RS06000	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
MF1_RS06005	ENOG4105CAK	Cell division ATP-binding protein ftsE
MF1_RS06020	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
MF1_RS06025	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
MF1_RS06045	ENOG4105CNU	cell division protein FtsK
MF1_RS06140	ENOG4105EGP	transfer protein
MF1_RS06155	ENOG4105E33	succinate dehydrogenase
MF1_RS06160	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
MF1_RS06175	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
MF1_RS06180	ENOG4105D6X	Specifically methylates guanosine-37 in various tRNAs (By similarity)
MF1_RS06185	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
MF1_RS06225	ENOG4105KDC	50s ribosomal protein l28
MF1_RS06235	ENOG4105DC1	bifunctional purine biosynthesis protein purh
MF1_RS06245	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
MF1_RS06250	ENOG4105D0M	Protease HtpX homolog
MF1_RS06260	ENOG4105K5M	30s ribosomal protein S16
MF1_RS06270	ENOG4105CB9	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
MF1_RS06280	ENOG4105C7I	Dehydrogenase
MF1_RS06290	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
MF1_RS06305	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
MF1_RS06315	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
MF1_RS06345	ENOG4107QX9	Thiol disulfide interChange protein
MF1_RS06385	ENOG4105DWF	phosphomethylpyrimidine kinase
MF1_RS06395	ENOG4105DZ1	carboxypeptidase
MF1_RS06405	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
MF1_RS06410	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
MF1_RS06420	ENOG4105KHV	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate (By similarity)
MF1_RS06425	ENOG4105D49	3-dehydroquinate synthase
MF1_RS06440	ENOG41069B0	Membrane-bound lysozyme-inhibitor of c-type lysozyme
MF1_RS06445	ENOG4105KJM	monovalent cation h antiporter subunit g
MF1_RS06450	ENOG4105W4C	monovalent cation H antiporter subunit F
MF1_RS06455	ENOG4105SC1	monovalent cation H antiporter subunit E
MF1_RS06460	ENOG4107R4Z	monovalent cation h antiporter subunit d
MF1_RS06465	ENOG4108ZE9	Monovalent cation H antiporter subunit C
MF1_RS06470	ENOG4105D65	subunit l
MF1_RS06480	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
MF1_RS06490	ENOG4107QN2	dihydrolipoyl dehydrogenase
MF1_RS06495	ENOG4105C7S	Dehydrogenase
MF1_RS06500	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
MF1_RS06510	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
MF1_RS06515	ENOG4105C80	Catalyzes the reversible oxidation of malate to oxaloacetate (By similarity)
MF1_RS06520	ENOG4105D6Z	AFG1 family ATPase
MF1_RS06530	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
MF1_RS06535	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
MF1_RS06540	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
MF1_RS06545	ENOG4107835	probably involved in intracellular septation (By similarity)
MF1_RS06550	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
MF1_RS06555	ENOG4105FA0	parb-like partition protein
MF1_RS06560	ENOG4107QJE	Chromosome Partitioning Protein
MF1_RS06565	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
MF1_RS06570	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
MF1_RS06575	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
MF1_RS06580	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)