locus-tag	class	description
H3299_RS00005	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H3299_RS00010	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
H3299_RS00015	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
H3299_RS00025	ENOG4105C5H	ABC transporter
H3299_RS00055	ENOG4105DZG	Dehydrogenase
H3299_RS00065	ENOG4105CFQ	glutamine synthetase
H3299_RS00070	ENOG4105CJP	fad dependent oxidoreductase
H3299_RS00075	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H3299_RS00090	ENOG4106V2I	dimethylaminohydrolase
H3299_RS00095	ENOG4105EAB	amino acid AbC transporter
H3299_RS00110	ENOG4108JEH	abc transporter atp-binding protein
H3299_RS00120	ENOG4105CSH	Transporter
H3299_RS00125	ENOG4105C7K	acetolactate synthase
H3299_RS00130	ENOG4105D2N	Aldolase
H3299_RS00135	ENOG4105CZI	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
H3299_RS00145	ENOG4105BZS	acriflavin resistance protein
H3299_RS00155	ENOG4105CUX	Signal transduction histidine kinase
H3299_RS00165	ENOG4105CIS	alcohol dehydrogenase
H3299_RS00185	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS00190	ENOG4107RCV	ABC transporter, permease
H3299_RS00200	ENOG4105D6F	Phosphatase
H3299_RS00225	ENOG41080HT	Transcriptional regulator, arsr family
H3299_RS00235	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
H3299_RS00240	ENOG4108V82	Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP dITP to their respective monophosphate derivatives. Might exclude non-canonical purines from DNA precursor pool, thus preventing their incorporation into DNA and avoiding chromosomal lesions (By similarity)
H3299_RS00245	ENOG4105CSA	Coproporphyrinogen iii oxidase
H3299_RS00300	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
H3299_RS00305	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
H3299_RS00310	ENOG4105YK5	50S ribosomal protein L36
H3299_RS00325	ENOG4105Y2X	UPF0335 protein
H3299_RS00330	ENOG4108IV0	ABC, transporter
H3299_RS00335	ENOG4105C0Z	ABC transporter
H3299_RS00350	ENOG4105CAD	extracellular ligand-binding receptor
H3299_RS00360	ENOG4107RAW	3-carboxy-cis-cis-muconate cycloisomerase
H3299_RS00370	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
H3299_RS00375	ENOG4105T38	integral membrane protein
H3299_RS00390	ENOG4108ZR6	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes (By similarity)
H3299_RS00400	ENOG4105BZ1	(ABC) transporter
H3299_RS00405	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
H3299_RS00415	ENOG4107RZC	phospholipase d
H3299_RS00425	ENOG4105C2X	Arabinose 5-phosphate isomerase
H3299_RS00440	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3299_RS00455	ENOG4105K6T	rare lipoprotein A
H3299_RS00460	ENOG4105CFH	Aspartokinase
H3299_RS00465	ENOG4108HRM	phosphoenolpyruvate--protein phosphotransferase
H3299_RS00475	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
H3299_RS00480	ENOG4105DJY	efflux transporter, rnd family, mfp subunit
H3299_RS00495	ENOG4105D8A	3-Deoxy-D-manno-octulosonic-acid transferase
H3299_RS00500	ENOG4105CHD	Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1- P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA) (By similarity)
H3299_RS00505	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H3299_RS00510	ENOG4107SPB	Catalyzes the conversion of 6-carboxy-5,6,7,8- tetrahydropterin (CPH4) to 7-carboxy-7-deazaguanine (CDG) (By similarity)
H3299_RS00515	ENOG4107ZIF	6-carboxy-5,6,7,8-tetrahydropterin synthase
H3299_RS00550	ENOG4105CQB	FAD linked oxidase domain protein
H3299_RS00560	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS00565	ENOG4105F38	ABC transporter, permease
H3299_RS00570	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H3299_RS00580	ENOG4105DMF	Dehydrogenase
H3299_RS00620	ENOG4108YZN	class I peptide chain release factor
H3299_RS00635	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
H3299_RS00640	ENOG4105CFG	Acts as a chaperone (By similarity)
H3299_RS00645	ENOG4105CH2	amidohydrolase
H3299_RS00650	ENOG4105CSH	Transporter
H3299_RS00660	ENOG4105CVE	Lytic murein transglycosylase
H3299_RS00670	ENOG4105H1G	trap transporter solute receptor taxi family
H3299_RS00680	ENOG4105E2Y	ABC, transporter
H3299_RS00690	ENOG4105CQX	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol (By similarity)
H3299_RS00700	ENOG4105DUY	Ser-Asp rich fibrinogen-binding, bone sialoprotein-binding protein
H3299_RS00705	ENOG4105C7I	Dehydrogenase
H3299_RS00710	ENOG4107B2H	carbonic anhydrase
H3299_RS00715	ENOG4107XGF	functions in a salvage pathway. Uses pyridoxamine (By similarity)
H3299_RS00740	ENOG4105C26	Dehydrogenase
H3299_RS00745	ENOG4105C10	Electron transfer flavoprotein
H3299_RS00750	ENOG4105BZJ	Electron transfer flavoprotein
H3299_RS00770	ENOG4107FKK	extracellular solute-binding protein family 1
H3299_RS00775	ENOG4105D38	putrescine abc transporter
H3299_RS00785	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS00790	ENOG4107R2I	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination. The AddA nuclease domain is required for chi fragment generation
H3299_RS00800	ENOG4108S0S	Nucleotidyl transferase
H3299_RS00805	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
H3299_RS00810	ENOG4107RT5	aminobenzoyl-glutamate utilization protein B
H3299_RS00840	ENOG4105H3G	oxidoreductase
H3299_RS00845	ENOG4105KME	endoribonuclease L-psp
H3299_RS00860	ENOG4107R11	Transcriptional regulator
H3299_RS00870	ENOG4107RM2	PTS IIA-like nitrogen-regulatory protein PtsN
H3299_RS00875	ENOG4107TNS	sigma 54 modulation protein ribosomal protein S30ea
H3299_RS00880	ENOG4105DTW	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3299_RS00885	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
H3299_RS00910	ENOG4105D86	that it carries out the mismatch recognition step. This protein has a weak ATPase activity (By similarity)
H3299_RS00920	ENOG4108S7T	Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) (By similarity)
H3299_RS00925	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
H3299_RS00935	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H3299_RS00940	ENOG4105W8H	transhydrogenase (subunit alpha
H3299_RS00945	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
H3299_RS00975	ENOG4105IX2	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA (By similarity)
H3299_RS00980	ENOG4108YH1	overproduction of this protein in Escherichia coli inhibits the F plasmid-mediated exclusion of bacteriophage T7
H3299_RS00995	ENOG4105EX2	Binding-protein-dependent transport systems, inner membrane component
H3299_RS01000	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS01015	ENOG4105D6Z	AFG1 family ATPase
H3299_RS01045	ENOG4107R1Y	fructose-bisphosphate aldolase
H3299_RS01060	ENOG4105RF0	OstA family
H3299_RS01065	ENOG4108IUZ	ABC transporter
H3299_RS01080	ENOG4105DR4	Methyltransferase
H3299_RS01115	ENOG4107SET	aldo keto reductase
H3299_RS01120	ENOG4108UMI	ABC transporter, permease
H3299_RS01125	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS01130	ENOG4105D01	(LipO)protein
H3299_RS01140	ENOG4108IV0	ABC, transporter
H3299_RS01145	ENOG4105C0Z	ABC transporter
H3299_RS01150	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
H3299_RS01155	ENOG4105C32	Amino acid ABC transporter (Permease)
H3299_RS01170	ENOG4105DGW	oligopeptidase A
H3299_RS01175	ENOG4105CJW	magnesium transporter
H3299_RS01190	ENOG4105CA9	Pyruvate kinase
H3299_RS01200	ENOG4105EKT	)-iron permease
H3299_RS01205	ENOG410650H	(LipO)protein
H3299_RS01225	ENOG4105DYT	3-hydroxyacyl-CoA dehydrogenase
H3299_RS01240	ENOG4107QM1	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
H3299_RS01255	ENOG4105CSH	Transporter
H3299_RS01265	ENOG4105CNN	ABC, transporter
H3299_RS01285	ENOG4105DFP	Integrase
H3299_RS01310	ENOG4107QMH	DNA methylase
H3299_RS01315	ENOG4107J0C	type IIi
H3299_RS01330	ENOG41074H6	response regulator
H3299_RS01345	ENOG41086Q3	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase (By similarity)
H3299_RS01350	ENOG4105BZU	Histidine kinase
H3299_RS01365	ENOG4105CM3	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate (By similarity)
H3299_RS01390	ENOG4105EJQ	L-serine dehydratase
H3299_RS01400	ENOG4107QIX	Phosphoglucomutase (EC 5.4.2.2
H3299_RS01405	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
H3299_RS01425	ENOG4105S0E	allantoin catabolism protein
H3299_RS01430	ENOG4105C6Y	Udp-glucose 6-dehydrogenase
H3299_RS01440	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
H3299_RS01445	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
H3299_RS01450	ENOG4107QVN	Key enzyme in the regulation of glycerol uptake and metabolism (By similarity)
H3299_RS01460	ENOG4105EFS	Binding-protein-dependent transport systems, inner membrane component
H3299_RS01500	ENOG4108UVJ	appr-1-p processing domain protein
H3299_RS01510	ENOG4105C9X	ppx gppa phosphatase
H3299_RS01540	ENOG4105SG9	biopolymer transport protein, ExbD
H3299_RS01545	ENOG4105E02	MotA TolQ exbB proton channel
H3299_RS01560	ENOG4105VFE	sira family
H3299_RS01570	ENOG4105F7V	ErfK ybiS ycfS ynhG family protein
H3299_RS01590	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
H3299_RS01595	ENOG4105D3U	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
H3299_RS01625	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
H3299_RS01630	ENOG4105E2S	oxidase) subunit II
H3299_RS01635	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H3299_RS01640	ENOG4105CCU	oxidase (Subunit III)
H3299_RS01645	ENOG41090KH	cytochrome o ubiquinol oxidase (subunit iv)
H3299_RS01650	ENOG4105DAA	L-lactate
H3299_RS01655	ENOG41073TP	transcriptional regulator
H3299_RS01660	ENOG4105DMF	Dehydrogenase
H3299_RS01680	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
H3299_RS01685	ENOG410626R	Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl- L-methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway (By similarity)
H3299_RS01690	ENOG4105MJ2	Competence protein
H3299_RS01695	ENOG41082FP	UPF0102 protein
H3299_RS01700	ENOG4105CU0	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA (By similarity)
H3299_RS01720	ENOG4105E0A	ABC, transporter
H3299_RS01755	ENOG4105D65	subunit l
H3299_RS01760	ENOG4108ZE9	Monovalent cation H antiporter subunit C
H3299_RS01765	ENOG4107R4Z	monovalent cation h antiporter subunit d
H3299_RS01770	ENOG4105SC1	monovalent cation H antiporter subunit E
H3299_RS01775	ENOG4105W4C	monovalent cation H antiporter subunit F
H3299_RS01785	ENOG4107Y2H	ErfK ybiS ycfS ynhG family protein
H3299_RS01795	ENOG4107QPK	)-transporter
H3299_RS01800	ENOG4105DG4	malate L-lactate dehydrogenase
H3299_RS01805	ENOG4108KAM	Transcriptional regulator
H3299_RS01815	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
H3299_RS01825	ENOG4106032	Glutathionylspermidine synthase
H3299_RS01830	ENOG4105F1G	UPF0441 protein
H3299_RS01835	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
H3299_RS01840	ENOG4105C9A	Phoh family
H3299_RS01850	ENOG4108JU5	Magnesium and cobalt efflux protein
H3299_RS01855	ENOG4105CE8	Transfers the fatty acyl group on membrane lipoproteins (By similarity)
H3299_RS01860	ENOG4108WRK	Transcriptional regulator
H3299_RS01865	ENOG4107TF3	peptidylprolyl cis-trans isomerase
H3299_RS01885	ENOG4108E87	P-loop hydrolase UPF0079
H3299_RS01890	ENOG4105I8F	Histidine kinase
H3299_RS01915	ENOG4108UW5	maltose o-acetyltransferase
H3299_RS01930	ENOG4105C8A	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP (By similarity)
H3299_RS01955	ENOG4105HFZ	Membrane
H3299_RS01960	ENOG4108I0Y	(ABC) transporter
H3299_RS01995	ENOG4108C33	Resolvase
H3299_RS02050	ENOG4105DWF	phosphomethylpyrimidine kinase
H3299_RS02060	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3299_RS02065	ENOG4107R37	Glutamate dehydrogenase
H3299_RS02085	ENOG4105D6W	Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps (By similarity)
H3299_RS02090	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H3299_RS02110	ENOG4105C54	Major Facilitator superfamily
H3299_RS02115	ENOG4105RPH	Inner membrane protein YddG
H3299_RS02120	ENOG4107EJG	GntR family transcriptional regulator
H3299_RS02125	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H3299_RS02130	ENOG4105C26	Dehydrogenase
H3299_RS02150	ENOG4105CDU	Replicative dna helicase
H3299_RS02185	ENOG4105R3P	Inner membrane protein yagU
H3299_RS02200	ENOG4105KCK	Peptidoglycan-associated lipoprotein
H3299_RS02205	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
H3299_RS02220	ENOG4105P5X	ATP phosphoribosyltransferase regulatory subunit
H3299_RS02240	ENOG4105XAB	Smr domain protein
H3299_RS02250	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
H3299_RS02275	ENOG410829K	Lysine exporter protein (Lyse ygga)
H3299_RS02280	ENOG4105C5I	Dehydrogenase
H3299_RS02290	ENOG4105C12	Phosphoribosylglycinamide synthetase
H3299_RS02295	ENOG4107SID	ATP-dependent exodnase (exonuclease v)
H3299_RS02310	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
H3299_RS02315	ENOG4105CAK	Cell division ATP-binding protein ftsE
H3299_RS02330	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
H3299_RS02340	ENOG4105F7P	transcriptional regulator AsnC family
H3299_RS02350	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
H3299_RS02360	ENOG4105G6Z	alkaline phosphatase
H3299_RS02365	ENOG4105C7N	Xanthine uracil vitamin C permease
H3299_RS02370	ENOG4105WMR	Protein CrcB homolog
H3299_RS02405	ENOG4105K63	Thioredoxin
H3299_RS02415	ENOG4105C25	Primosomal protein n'
H3299_RS02420	ENOG4108Z7F	N-acetyltransferase
H3299_RS02435	ENOG4108Z6B	deaminase
H3299_RS02445	ENOG4107QPK	)-transporter
H3299_RS02470	ENOG4105EF7	Transcriptional regulator
H3299_RS02475	ENOG4107FQX	Alpha-acetolactate decarboxylase
H3299_RS02505	ENOG4105BZJ	Electron transfer flavoprotein
H3299_RS02510	ENOG4105C10	Electron transfer flavoprotein
H3299_RS02520	ENOG4108MEK	Metal-binding protein YodA
H3299_RS02535	ENOG4107YZX	Universal stress protein
H3299_RS02540	ENOG4105DZ1	carboxypeptidase
H3299_RS02550	ENOG4105MQS	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate (By similarity)
H3299_RS02565	ENOG4105CPQ	Dehydrogenase
H3299_RS02580	ENOG4107YD3	Thioesterase
H3299_RS02590	ENOG4105KA4	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB (By similarity)
H3299_RS02600	ENOG4107RBI	VanW family
H3299_RS02635	ENOG41072GX	Peptidase M22 Glycoprotease
H3299_RS02645	ENOG41080Z8	PHOSPHOCARRIER protein
H3299_RS02655	ENOG4105D1C	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion (By similarity)
H3299_RS02660	ENOG4105EB3	Histidine kinase
H3299_RS02665	ENOG4105E3W	Two component transcriptional regulator (Winged helix family
H3299_RS02685	ENOG4105DXD	2-methylcitrate dehydratase
H3299_RS02695	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
H3299_RS02710	ENOG4105CKI	cobalamin synthesis protein
H3299_RS02715	ENOG4105KSC	Transcriptional regulator, TraR DksA family
H3299_RS02725	ENOG4105BZU	Histidine kinase
H3299_RS02730	ENOG4105CF3	3-Hydroxyisobutyrate dehydrogenase
H3299_RS02735	ENOG4105D05	Receptor
H3299_RS02740	ENOG4105NIV	Esterase
H3299_RS02750	ENOG4105DHS	permease protein
H3299_RS02755	ENOG4105CM4	permease protein
H3299_RS02760	ENOG4108IPW	abc transporter atp-binding protein
H3299_RS02770	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H3299_RS02785	ENOG4105DFI	Membrane
H3299_RS02795	ENOG4108WN0	inhibitor of vertebrate lysozyme
H3299_RS02810	ENOG4106SNF	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H3299_RS02840	ENOG4108Q5F	Tetr family transcriptional regulator
H3299_RS02865	ENOG4105KW6	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance (By similarity)
H3299_RS02875	ENOG4105DFH	Transport of potassium into the cell (By similarity)
H3299_RS02885	ENOG4105SYT	Methylenetetrahydrofolate reductase
H3299_RS02890	ENOG41089UC	methyltransferase, type 11
H3299_RS02930	ENOG4108IJ6	ABC transporter
H3299_RS02940	ENOG4105E0C	molybdate abc transporter
H3299_RS02945	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
H3299_RS02965	ENOG4105EH2	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr) (By similarity)
H3299_RS02975	ENOG4105HPZ	Involved in the removal of murein from the sacculus. May also facilitate integration of nascent murein strands into the sacculus by cleaving the peptide bonds between neighboring strands in mature murein (By similarity)
H3299_RS02985	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
H3299_RS02995	ENOG4105DWV	Homoserine O-trans-acetylase
H3299_RS03000	ENOG4105DWV	Homoserine O-trans-acetylase
H3299_RS03030	ENOG4105BZ6	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides (By similarity)
H3299_RS03055	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
H3299_RS03065	ENOG4105ECC	imidazole-glycerol-phosphate dehydratase
H3299_RS03075	ENOG4105BZU	Histidine kinase
H3299_RS03080	ENOG4105CSR	polyphosphate kinase 2
H3299_RS03085	ENOG4106PMH	Extracellular solute-binding protein family 3
H3299_RS03090	ENOG4105C5I	Dehydrogenase
H3299_RS03100	ENOG4105K5G	30S ribosomal protein S21
H3299_RS03120	ENOG4108UKH	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides (By similarity)
H3299_RS03160	ENOG4107S78	Band 7 protein
H3299_RS03175	ENOG4105DFA	alanine racemase domain protein
H3299_RS03180	ENOG4105C20	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu) (By similarity)
H3299_RS03185	ENOG4105C4K	Nad synthetase
H3299_RS03190	ENOG4105C7V	phospho-2-dehydro-3-deoxyheptonate aldolase
H3299_RS03205	ENOG4105E66	phosphoriboisomerase A
H3299_RS03225	ENOG41086VY	Fic/DOC family
H3299_RS03230	ENOG4108R5P	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery (By similarity)
H3299_RS03235	ENOG4105C4N	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis (By similarity)
H3299_RS03270	ENOG4108XC3	NADH ubiquinone oxidoreductase
H3299_RS03275	ENOG4105G5W	regulator Fur family
H3299_RS03290	ENOG4105KVH	Transcriptional regulator
H3299_RS03295	ENOG4108RYK	Nad-dependent epimerase dehydratase
H3299_RS03300	ENOG4107MII	Sugar-specific transcriptional regulator TrmB
H3299_RS03310	ENOG4105CKI	cobalamin synthesis protein
H3299_RS03320	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H3299_RS03325	ENOG4105BZM	domain protein
H3299_RS03355	ENOG4105BZ1	(ABC) transporter
H3299_RS03360	ENOG4105EI2	Pseudouridine synthase
H3299_RS03385	ENOG4105EZI	multiple antibiotic resistance (MarC)-related protein
H3299_RS03390	ENOG4105S6R	Iron-hydroxamate transporter permease subunit
H3299_RS03400	ENOG4105E0K	tonB-dependent siderophore receptor
H3299_RS03405	ENOG4108WFR	AraC Family Transcriptional Regulator
H3299_RS03410	ENOG4105E0A	ABC, transporter
H3299_RS03415	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3299_RS03420	ENOG4108ZEF	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate (By similarity)
H3299_RS03435	ENOG4105E2N	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA) (By similarity)
H3299_RS03455	ENOG4105DEN	Luciferase family
H3299_RS03470	ENOG4105C26	Dehydrogenase
H3299_RS03535	ENOG4108UH4	Binds specifically to the SsrA RNA (tmRNA) and is required for stable association of SsrA with ribosomes (By similarity)
H3299_RS03545	ENOG4105D2S	major facilitator superfamily
H3299_RS03555	ENOG4105EAH	synthase
H3299_RS03570	ENOG4105C38	Glycyl-tRNA synthetase beta subunit
H3299_RS03575	ENOG4105C5Z	peptidase
H3299_RS03580	ENOG4106E5D	Protein of unknown function (DUF461)
H3299_RS03590	ENOG4107R03	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate (By similarity)
H3299_RS03610	ENOG4105C3F	Signal peptidase i
H3299_RS03625	ENOG4105EPU	Molybdenum cofactor synthesis domain protein
H3299_RS03635	ENOG4105JIE	May be involved in the transport of PQQ or its precursor to the periplasm (By similarity)
H3299_RS03640	ENOG41086XE	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ (By similarity)
H3299_RS03645	ENOG4105Z85	coenzyme PQQ synthesis
H3299_RS03650	ENOG4105EZY	Pyrroloquinoline quinone biosynthesis protein E
H3299_RS03655	ENOG4108UMA	3-octaprenyl-4-hydroxybenzoate carboxy-lyase
H3299_RS03660	ENOG4105D3H	Catalyzes the decarboxylation of 3-octaprenyl-4-hydroxy benzoate to 2-octaprenylphenol (By similarity)
H3299_RS03685	ENOG4105DZG	Dehydrogenase
H3299_RS03715	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H3299_RS03740	ENOG41087AY	ADP-Ribose pyrophosphatase
H3299_RS03745	ENOG4108S10	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H3299_RS03750	ENOG4105KAF	membrAne
H3299_RS03755	ENOG4105HDK	L-asparaginase
H3299_RS03765	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
H3299_RS03780	ENOG4105DS0	Transcriptional regulator, Crp Fnr family
H3299_RS03785	ENOG4105D4P	Coproporphyrinogen iii oxidase
H3299_RS03805	ENOG4108VBV	N-Acetylmuramoyl-L-alanine amidase
H3299_RS03810	ENOG41066UG	Regulatory DnaK co-chaperone. Direct interaction between DnaK and DjlA is needed for the induction of the wcaABCDE operon, involved in the synthesis of a colanic acid polysaccharide capsule, possibly through activation of the RcsB RcsC phosphotransfer signaling pathway. The colanic acid capsule may help the bacterium survive conditions outside the host (By similarity)
H3299_RS03840	ENOG4108K3A	Glutathione S-transferase
H3299_RS03850	ENOG4105CUX	Signal transduction histidine kinase
H3299_RS03855	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H3299_RS03860	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H3299_RS03870	ENOG410683Z	Preprotein translocase SecE subunit
H3299_RS03885	ENOG4105C64	Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release (By similarity)
H3299_RS03895	ENOG4105KBC	Seems to be the binding site for several of the factors involved in protein synthesis and appears to be essential for accurate translation (By similarity)
H3299_RS03905	ENOG4107QIH	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H3299_RS03910	ENOG4105D27	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H3299_RS03930	ENOG4105BZU	Histidine kinase
H3299_RS03940	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H3299_RS03955	ENOG4105D7A	ATP-binding protein
H3299_RS03990	ENOG4108IJ9	(ABC) transporter
H3299_RS03995	ENOG41070EG	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes (By similarity)
H3299_RS04000	ENOG4105D22	carbon starvation protein
H3299_RS04005	ENOG4105VCD	cytoplasmic protein
H3299_RS04010	ENOG4105CKI	cobalamin synthesis protein
H3299_RS04020	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
H3299_RS04025	ENOG4105G3E	Probably involved in ribonucleotide reductase function (By similarity)
H3299_RS04030	ENOG4105WAZ	(Glutaredoxin-like protein) NrdH
H3299_RS04035	ENOG4105EXG	Transcriptional regulator
H3299_RS04040	ENOG4105VFG	Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits (By similarity)
H3299_RS04055	ENOG4105EU0	Major facilitator Superfamily
H3299_RS04060	ENOG4107SC1	transglycosylase
H3299_RS04075	ENOG4105M4H	endoribonuclease L-psp
H3299_RS04090	ENOG4108YYH	Nadph-dependent fmn reductase
H3299_RS04115	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
H3299_RS04120	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
H3299_RS04140	ENOG4105D42	Cleaves the N-terminal amino acid of tripeptides (By similarity)
H3299_RS04145	ENOG4105DEF	Extracellular solute-binding protein, family 5
H3299_RS04155	ENOG4107SET	aldo keto reductase
H3299_RS04160	ENOG4105VUF	Transcriptional regulator
H3299_RS04170	ENOG4105CEN	a g-specific adenine glycosylase
H3299_RS04175	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3299_RS04180	ENOG4108BDP	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
H3299_RS04190	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
H3299_RS04195	ENOG4105CAA	catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
H3299_RS04200	ENOG41080G2	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
H3299_RS04215	ENOG4105VEQ	Cold shock protein
H3299_RS04225	ENOG4108UJU	UPF0301 protein
H3299_RS04245	ENOG4105EFQ	Two component transcriptional regulator (Winged helix family
H3299_RS04270	ENOG410839H	phosphoribosylformylglycinamidine synthase
H3299_RS04285	ENOG4107QIK	phosphoribosylformylglycinamidine synthase
H3299_RS04305	ENOG4105VE1	Phosphatidylcholine synthase
H3299_RS04315	ENOG4105DZ1	carboxypeptidase
H3299_RS04325	ENOG4107QRG	dna polymerase iii
H3299_RS04330	ENOG4105CKH	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (By similarity)
H3299_RS04335	ENOG4105F8V	Hydrolase, tatD family
H3299_RS04340	ENOG4108H5C	Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate-dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate (By similarity)
H3299_RS04345	ENOG4105W0E	50S ribosomal protein L33
H3299_RS04385	ENOG4108V3G	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity (By similarity)
H3299_RS04390	ENOG4105MDH	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity (By similarity)
H3299_RS04395	ENOG4105DEA	Involved in protein export. Acts as a chaperone by maintaining the newly synthesized protein in an open conformation
H3299_RS04415	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
H3299_RS04420	ENOG4105C9X	ppx gppa phosphatase
H3299_RS04425	ENOG4105D1U	peptidase U62 modulator of DNA gyrase
H3299_RS04440	ENOG4105C1J	atp-dependent rna helicase
H3299_RS04445	ENOG4105DYA	Acts on guanine, xanthine and to a lesser extent hypoxanthine (By similarity)
H3299_RS04450	ENOG41062IR	nudix hydrolase
H3299_RS04465	ENOG4108YXV	Transcriptional regulator
H3299_RS04470	ENOG4105E0X	reductase
H3299_RS04475	ENOG4105BZ1	(ABC) transporter
H3299_RS04480	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
H3299_RS04495	ENOG4105DU1	integral membrane protein, terc
H3299_RS04500	ENOG4108IPX	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS04505	ENOG4105EHG	Permease protein
H3299_RS04515	ENOG4106QJH	hemin transport protein
H3299_RS04535	ENOG4105CQ0	ABC transporter
H3299_RS04560	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
H3299_RS04565	ENOG4105UBK	short-chain dehydrogenase reductase
H3299_RS04570	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
H3299_RS04590	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
H3299_RS04595	ENOG4108ZDX	Binds together with S18 to 16S ribosomal RNA (By similarity)
H3299_RS04600	ENOG4105DR1	Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration (By similarity)
H3299_RS04610	ENOG4105C5F	glutamine synthetase
H3299_RS04630	ENOG4105C03	ribonuclease
H3299_RS04635	ENOG4105C5C	n-acetylmuramoyl-l-alanine amidase
H3299_RS04655	ENOG4107QIV	Cytochrome c biogenesis protein
H3299_RS04660	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
H3299_RS04670	ENOG41083BM	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H3299_RS04675	ENOG4105C66	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate (By similarity)
H3299_RS04690	ENOG4105FR1	rard protein
H3299_RS04695	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H3299_RS04745	ENOG4105C2N	RNA methyltransferase TrmH family group 3
H3299_RS04805	ENOG4107TK4	histidinol-phosphate phosphatase
H3299_RS04815	ENOG4108ZNX	Heat shock protein
H3299_RS04830	ENOG4105CRQ	synthase (Component I)
H3299_RS04850	ENOG4105CD3	dihydroorotase
H3299_RS04860	ENOG4105CBT	Fructose-1,6-bisphosphatase
H3299_RS04865	ENOG4105D6E	homoserine dehydrogenase
H3299_RS04870	ENOG4105CHM	Aminotransferase
H3299_RS04895	ENOG4105C79	DNA protecting protein DprA
H3299_RS04910	ENOG4105C40	3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs (By similarity)
H3299_RS04915	ENOG4105CSH	Transporter
H3299_RS04920	ENOG4105CQB	FAD linked oxidase domain protein
H3299_RS04925	ENOG4105N5Q	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0) (By similarity)
H3299_RS04930	ENOG4108VHN	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity)
H3299_RS04935	ENOG4105VD1	ATP synthase subunit C
H3299_RS04940	ENOG4105EE4	it plays a direct role in the translocation of protons across the membrane (By similarity)
H3299_RS04955	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
H3299_RS04965	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
H3299_RS04975	ENOG4108J2R	molybdopterin oxidoreductase
H3299_RS04985	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
H3299_RS04990	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
H3299_RS04995	ENOG41067S4	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system (By similarity)
H3299_RS05005	ENOG4105DCX	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. Together with TatB, TatC is part of a receptor directly interacting with Tat signal peptides (By similarity)
H3299_RS05010	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
H3299_RS05015	ENOG4105CV2	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates (By similarity)
H3299_RS05020	ENOG4105E26	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins (By similarity)
H3299_RS05025	ENOG4108K5P	(LipO)protein
H3299_RS05035	ENOG4105M00	molybdopterin converting factor, subunit 1
H3299_RS05040	ENOG4108ZAF	Molybdopterin
H3299_RS05050	ENOG4105DJV	ribulose-phosphate 3-epimerase
H3299_RS05055	ENOG4105C83	adenylosuccinate lyase
H3299_RS05065	ENOG4108UGX	Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate (By similarity)
H3299_RS05070	ENOG4105C5H	ABC transporter
H3299_RS05085	ENOG4105VG1	fes assembly suf system protein
H3299_RS05095	ENOG4105JRK	feS assembly protein SufD
H3299_RS05100	ENOG4105C3K	feS assembly ATPase SufC
H3299_RS05110	ENOG4105C3J	Cysteine desulfurase
H3299_RS05115	ENOG4105DHZ	alpha beta
H3299_RS05130	ENOG4105EEI	dihydropteroate synthase
H3299_RS05135	ENOG4105K8U	2-Amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
H3299_RS05140	ENOG4108EC8	DNA internalization-related competence protein ComEC
H3299_RS05160	ENOG4108JJA	ABC, transporter
H3299_RS05175	ENOG4106ABQ	septum formation initiator
H3299_RS05180	ENOG4108JYK	Dehydrogenase
H3299_RS05185	ENOG4105CPP	Dehydrogenase, E1 component
H3299_RS05190	ENOG4105C7S	Dehydrogenase
H3299_RS05195	ENOG4107QN2	dihydrolipoyl dehydrogenase
H3299_RS05200	ENOG4105C0G	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives (By similarity)
H3299_RS05205	ENOG4108Z1B	Cyclase dehydrase
H3299_RS05240	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H3299_RS05245	ENOG4105ZWB	Outer membrane lipoprotein
H3299_RS05255	ENOG4105G5H	Membrane
H3299_RS05260	ENOG4107QX8	SPFH domain, Band 7 family protein
H3299_RS05265	ENOG4105CCG	Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is tranferred onto alpha-ketoisovalerate to form ketopantoate (By similarity)
H3299_RS05280	ENOG4105CVM	Molybdenum cofactor synthesis domain protein
H3299_RS05285	ENOG4108YXW	Together with MoaA, is involved in the conversion of 5'- GTP to cyclic pyranopterin monophosphate (cPMP or molybdopterin precursor Z) (By similarity)
H3299_RS05290	ENOG4105DK0	Indole-3-glycerol phosphate synthase
H3299_RS05295	ENOG4107QYG	anthranilate phosphoribosyltransferase
H3299_RS05310	ENOG4105QUC	reductase
H3299_RS05335	ENOG4105BZ9	Cytochrome C oxidase, subunit I
H3299_RS05340	ENOG4105F1R	Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group (By similarity)
H3299_RS05350	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
H3299_RS05355	ENOG4105CUV	Homoserine Kinase
H3299_RS05365	ENOG4105EFP	binding-protein-dependent transport systems inner membrane Component
H3299_RS05380	ENOG4105C7F	AcnD-accessory protein PrpF
H3299_RS05385	ENOG4105F04	LysR family Transcriptional regulator
H3299_RS05395	ENOG4105CU7	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome (By similarity)
H3299_RS05400	ENOG4105CE9	30S ribosomal protein S2
H3299_RS05415	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
H3299_RS05425	ENOG4105C1A	potassium transporter peripheral membrane
H3299_RS05430	ENOG4105C1W	two component, sigma54 specific, transcriptional regulator, Fis family
H3299_RS05435	ENOG4105ES5	Histidine kinase
H3299_RS05440	ENOG4105KPV	Transcriptional regulator
H3299_RS05445	ENOG4108UH8	Involved in the biosynthesis of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP), two major building blocks of isoprenoid compounds. Catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (By similarity)
H3299_RS05450	ENOG4108I62	cina-like protein
H3299_RS05465	ENOG4108XG2	Histidine kinase
H3299_RS05470	ENOG4105HHA	aminodeoxychorismate lyase
H3299_RS05480	ENOG4108JIJ	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second (By similarity)
H3299_RS05490	ENOG4105CYQ	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate) (By similarity)
H3299_RS05495	ENOG4105C8N	cysteinyl-tRNA synthetase
H3299_RS05505	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H3299_RS05510	ENOG4107QKS	N-acylglucosamine 2-epimerase
H3299_RS05515	ENOG4108ZHJ	Organic hydroperoxide resistance protein
H3299_RS05520	ENOG4105CD8	aminopeptidase N
H3299_RS05530	ENOG4108UN4	phage SPO1 DNA polymerase-related protein
H3299_RS05535	ENOG4105D7X	high-affinity nickel-transporter
H3299_RS05550	ENOG4105FAV	ABC, transporter
H3299_RS05590	ENOG4105D7W	serine acetyltransferase
H3299_RS05595	ENOG4105K78	MarR family Transcriptional regulator
H3299_RS05605	ENOG4105K8F	Phosphoribosyl-amp cyclohydrolase
H3299_RS05620	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
H3299_RS05625	ENOG4105C26	Dehydrogenase
H3299_RS05640	ENOG4105CDA	abc transporter atp-binding protein
H3299_RS05645	ENOG4105DRP	amino acid AbC transporter
H3299_RS05650	ENOG4105EZ7	amino acid ABC transporter
H3299_RS05655	ENOG4107QXX	ABC transporter
H3299_RS05660	ENOG4105C28	cystathionine
H3299_RS05670	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
H3299_RS05675	ENOG4105C0H	protease
H3299_RS05695	ENOG4105D1W	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate (By similarity)
H3299_RS05705	ENOG4108UTT	Catalyzes the formation of 6,7-dimethyl-8- ribityllumazine by condensation of 5-amino-6-(D- ribitylamino)uracil with 3,4-dihydroxy-2-butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin (By similarity)
H3299_RS05720	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
H3299_RS05725	ENOG4105BZN	citrate synthase
H3299_RS05755	ENOG4105CA1	Removes the N-terminal methionine from nascent proteins (By similarity)
H3299_RS05760	ENOG4105PW4	Sugar fermentation stimulation protein homolog
H3299_RS05765	ENOG4105CVS	RNA methyltransferase TrmH family, group 1
H3299_RS05770	ENOG4105F03	Provides the (R)-glutamate required for cell wall biosynthesis (By similarity)
H3299_RS05780	ENOG4105DBD	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation (By similarity)
H3299_RS05785	ENOG41076YT	nitrate reductase, gamma subunit
H3299_RS05790	ENOG4105R3A	Nitrate reductase
H3299_RS05795	ENOG4108IUE	nitrate reductase beta subunit
H3299_RS05800	ENOG4105CRU	nitrate reductase, alpha subunit
H3299_RS05805	ENOG4105DQQ	Major facilitator superfamily MFS_1
H3299_RS05835	ENOG4107Z7P	Ferredoxin
H3299_RS05850	ENOG4105C0Y	Responsible for the amidation of carboxylic groups at position A and C of either cobyrinic acid or hydrogenobrynic acid. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation (By similarity)
H3299_RS05855	ENOG4105F27	Major Facilitator
H3299_RS05875	ENOG4105C0H	protease
H3299_RS05880	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H3299_RS05890	ENOG4105CE6	Adenylation and deadenylation of glutamate--ammonia ligase (By similarity)
H3299_RS05895	ENOG4105CUB	amino acid
H3299_RS05905	ENOG4107TQK	Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group (By similarity)
H3299_RS05910	ENOG4105D52	delta-aminolevulinic acid dehydratase
H3299_RS05925	ENOG4105G6W	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit (By similarity)
H3299_RS05930	ENOG4105CB3	Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) (By similarity)
H3299_RS05935	ENOG4105C85	amino acid
H3299_RS05955	ENOG4105CSD	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1) (By similarity)
H3299_RS05960	ENOG4105FD2	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0)) (By similarity)
H3299_RS05965	ENOG4105CEH	Catalyzes the synthesis of dihydrouridine a modified base found in the D-loop of most tRNAs (By similarity)
H3299_RS05970	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
H3299_RS05980	ENOG4108YXY	alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
H3299_RS05990	ENOG4105E43	Extracellular solute-binding protein, family 5
H3299_RS06000	ENOG4108ZG0	Ompa motb domain protein
H3299_RS06005	ENOG4105D1H	recombination factor protein RarA
H3299_RS06010	ENOG4107RTZ	reductase
H3299_RS06045	ENOG4108XM1	transcriptional regulator AsnC family
H3299_RS06060	ENOG4105CJR	Integral membrane protein (MviN
H3299_RS06085	ENOG4105CHM	Aminotransferase
H3299_RS06090	ENOG4105D0M	Protease HtpX homolog
H3299_RS06100	ENOG4105KM4	Acetyl-CoA carboxylase, biotin carboxyl carrier protein
H3299_RS06105	ENOG4105CER	acetyl-CoA carboxylase biotin carboxylase
H3299_RS06110	ENOG4108R4Z	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine (By similarity)
H3299_RS06120	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
H3299_RS06125	ENOG4105NTZ	Preprotein translocase subunit SecG
H3299_RS06130	ENOG4105CP7	Triose-phosphate isomerase
H3299_RS06135	ENOG4108J2R	molybdopterin oxidoreductase
H3299_RS06140	ENOG4108SBI	Involved in the biogenesis of TorA. Acts on TorA before the insertion of the molybdenum cofactor and, as a result, probably favors a conformation of the apoenzyme that is competent for acquiring the cofactor (By similarity)
H3299_RS06145	ENOG4105CE2	Aldehyde oxidase and xanthine dehydrogenase, molybdopterin binding
H3299_RS06155	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
H3299_RS06160	ENOG4108VCV	Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another (By similarity)
H3299_RS06180	ENOG4105D0V	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H3299_RS06185	ENOG4105D6S	protein involved in catabolism of external DNA
H3299_RS06195	ENOG4105DXX	methyltransferase
H3299_RS06200	ENOG4105DHU	Bile acid
H3299_RS06205	ENOG4108Z0R	Transferase
H3299_RS06210	ENOG4105C6Z	Gluconate
H3299_RS06215	ENOG4108Z67	carbohydrate kinase, thermoresistant glucokinase family
H3299_RS06220	ENOG4105C31	Tryptophanyl-tRNA synthetase
H3299_RS06225	ENOG4108SNX	Mammalian cell entry related domain protein
H3299_RS06235	ENOG4108SNX	Mammalian cell entry related domain protein
H3299_RS06245	ENOG4105CY3	ABC transporter, permease
H3299_RS06255	ENOG4105C6K	Malic enzyme
H3299_RS06260	ENOG4105J3Q	acyl carrier protein
H3299_RS06265	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H3299_RS06270	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H3299_RS06285	ENOG4105CIA	precorrin-4 C(11)-methyltransferase
H3299_RS06310	ENOG4105VIE	preprotein translocase, subunit YajC
H3299_RS06320	ENOG4105C6R	Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo- MPT) cofactor (Moco or molybdenum cofactor) to form Mo- molybdopterin guanine dinucleotide (Mo-MGD) cofactor (By similarity)
H3299_RS06330	ENOG4108TGY	Glutathione S-transferase
H3299_RS06340	ENOG4108RG0	uracil-dna glycosylase
H3299_RS06350	ENOG4105CUP	Catalyzes the synthesis of alpha-ribazole-5'-phosphate from nicotinate mononucleotide (NAMN) and 5,6- dimethylbenzimidazole (DMB) (By similarity)
H3299_RS06360	ENOG4105EAB	amino acid AbC transporter
H3299_RS06370	ENOG4108HW4	amino acid AbC transporter
H3299_RS06375	ENOG4105E5Q	amino acid AbC transporter
H3299_RS06380	ENOG4105CDA	abc transporter atp-binding protein
H3299_RS06385	ENOG4105CTU	Proline racemase
H3299_RS06390	ENOG4105DG4	malate L-lactate dehydrogenase
H3299_RS06400	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
H3299_RS06405	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H3299_RS06430	ENOG4105CM6	amino acid regulated cytosolic protein
H3299_RS06435	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
H3299_RS06450	ENOG4105DZ1	carboxypeptidase
H3299_RS06470	ENOG4105CQB	FAD linked oxidase domain protein
H3299_RS06480	ENOG4105KHC	sulfurtransferase
H3299_RS06485	ENOG4105C6T	cysteine synthase
H3299_RS06515	ENOG4107YAQ	Catalyzes the reduction of FMN to FMNH2 which is used to reduce pyrimidine by RutA via the Rut pathway (By similarity)
H3299_RS06525	ENOG4105DU0	nucleoside hydrolase
H3299_RS06530	ENOG4105CSH	Transporter
H3299_RS06565	ENOG4105E7H	involved in the assembly of LPS in the outer leaflet of the outer membrane. Determines N-hexane tolerance and is involved in outer membrane permeability. Essential for envelope biogenesis (By similarity)
H3299_RS06575	ENOG4105CEZ	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP) (By similarity)
H3299_RS06585	ENOG4105DAF	Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H3299_RS06595	ENOG4105D7M	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity)
H3299_RS06600	ENOG4105E1Z	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
H3299_RS06605	ENOG4105DZP	Membrane-associated zinc metalloprotease
H3299_RS06625	ENOG4108YX9	iron--sulfur cluster insertion protein erpA
H3299_RS06635	ENOG4108KK1	membrane protein AbrB duplication
H3299_RS06640	ENOG4105DWA	May conjugate Arg from its aminoacyl-tRNA to the N- termini of proteins containing an N-terminal aspartate or glutamate
H3299_RS06665	ENOG4105KAV	tspo and mbr like protein
H3299_RS06670	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
H3299_RS06675	ENOG4105K59	histidine triad (HIT) protein
H3299_RS06680	ENOG4105CDA	abc transporter atp-binding protein
H3299_RS06695	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
H3299_RS06710	ENOG4108V3E	phosphoribosylglycinamide formyltransferase
H3299_RS06720	ENOG4105C02	permease
H3299_RS06725	ENOG4105CI4	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids (By similarity)
H3299_RS06730	ENOG4105C1V	Peptidase, M16
H3299_RS06740	ENOG4105DTN	riboflavin biosynthesis protein ribF
H3299_RS06745	ENOG4108WIW	Aspartyl protease
H3299_RS06750	ENOG4105KWW	Biogenesis protein
H3299_RS06755	ENOG4105DA4	cytochrome c-type biogenesis protein
H3299_RS06760	ENOG4108ZKK	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH (By similarity)
H3299_RS06775	ENOG4105DQ4	alcohol dehydrogenase
H3299_RS06785	ENOG4105DIT	ErfK YbiS YcfS YnhG family protein
H3299_RS06800	ENOG4105IFJ	Histidine kinase
H3299_RS06805	ENOG4105XJC	Two component transcriptional regulator (Winged helix family
H3299_RS06815	ENOG4108JQC	penicillin-binding protein 1A
H3299_RS06855	ENOG4105HMI	Membrane
H3299_RS06870	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
H3299_RS06880	ENOG4108RA9	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body (By similarity)
H3299_RS06890	ENOG4108R5J	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center (By similarity)
H3299_RS06900	ENOG4105VBI	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site (By similarity)
H3299_RS06910	ENOG4105KAR	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit (By similarity)
H3299_RS06915	ENOG4108UNN	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome (By similarity)
H3299_RS06930	ENOG4108R70	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs (By similarity)
H3299_RS06945	ENOG4105K7S	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA (By similarity)
H3299_RS06950	ENOG4105CFD	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
H3299_RS06960	ENOG4106U5A	One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome (By similarity)
H3299_RS06965	ENOG4105EEE	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit (By similarity)
H3299_RS06975	ENOG4105CGV	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis (By similarity)
H3299_RS06990	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
H3299_RS07005	ENOG4107RP9	extracellular solute-binding protein, family 3
H3299_RS07010	ENOG4105EAD	ABC transporter
H3299_RS07015	ENOG4105DRP	amino acid AbC transporter
H3299_RS07020	ENOG4105CDA	abc transporter atp-binding protein
H3299_RS07035	ENOG4108M8W	Monooxygenase
H3299_RS07050	ENOG4105C26	Dehydrogenase
H3299_RS07055	ENOG4105EAQ	(twin-arginine translocation) pathway signal
H3299_RS07075	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
H3299_RS07120	ENOG4105EEQ	Na H antiporter
H3299_RS07130	ENOG4105P9C	Participates in cysteine desulfuration mediated by SufS. Cysteine desulfuration mobilizes sulfur from L-cysteine to yield L-alanine and constitutes an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Functions as a sulfur acceptor for SufS, by mediating the direct transfer of the sulfur atom from the S-sulfanylcysteine of SufS, an intermediate product of cysteine desulfuration process (By similarity)
H3299_RS07160	ENOG4105C3T	may be the GTPase, regulating ATP sulfurylase activity (By similarity)
H3299_RS07170	ENOG4105ET3	Reduction of activated sulfate into sulfite (By similarity)
H3299_RS07185	ENOG4105DS7	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair (By similarity)
H3299_RS07200	ENOG4105CX4	Precorrin-6y C5,15-methyltransferase
H3299_RS07205	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
H3299_RS07210	ENOG41081F0	Precorrin-8x methylmutase
H3299_RS07215	ENOG4105DVK	Precorrin-2 c20-methyltransferase
H3299_RS07235	ENOG4105DXN	mazG family
H3299_RS07240	ENOG4105CMR	udp-glucose 4-epimerase
H3299_RS07250	ENOG4105EE5	Membrane protein terC
H3299_RS07265	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
H3299_RS07270	ENOG4105P8F	nudix hydrolase
H3299_RS07275	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
H3299_RS07300	ENOG4107T8T	UPF0173 metal-dependent hydrolase
H3299_RS07305	ENOG4107ZJC	Could be a nuclease that resolves Holliday junction intermediates in genetic recombination (By similarity)
H3299_RS07330	ENOG4105C2C	drug resistance transporter, Bcr CflA
H3299_RS07335	ENOG4105CB5	ATP-dependent DNA helicase recG
H3299_RS07365	ENOG4107VRP	DNA repair exonuclease
H3299_RS07370	ENOG4106D4I	domain protein
H3299_RS07375	ENOG4105CEC	DNA methylase N-4 N-6
H3299_RS07395	ENOG41083MR	nifu domain-containing protein
H3299_RS07410	ENOG4105BZU	Histidine kinase
H3299_RS07475	ENOG4105NI8	Cytosine-specific methyltransferase
H3299_RS07550	ENOG4105CM2	brancheD-chain amino acid aminotransferase
H3299_RS07560	ENOG4105K4P	CoA-binding domain protein
H3299_RS07565	ENOG4108UM5	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly (By similarity)
H3299_RS07570	ENOG4108UJD	30S ribosomal protein S9
H3299_RS07580	ENOG41067MG	lrgb family
H3299_RS07585	ENOG4105VAW	lrga family
H3299_RS07590	ENOG4105CMU	LysR family (Transcriptional regulator
H3299_RS07605	ENOG4105ZIE	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides (By similarity)
H3299_RS07610	ENOG4105C9M	aspartyl-trna synthetase
H3299_RS07615	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
H3299_RS07625	ENOG4108UXN	response regulator
H3299_RS07630	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
H3299_RS07655	ENOG4105CTF	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates (By similarity)
H3299_RS07665	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
H3299_RS07670	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
H3299_RS07675	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
H3299_RS07680	ENOG4105C1J	atp-dependent rna helicase
H3299_RS07690	ENOG4105C7B	Threonine dehydratase
H3299_RS07920	ENOG4105NVB	glycoside hydrolase, family 19
H3299_RS07995	ENOG4105EGS	Mechanosensitive ion channel
H3299_RS08010	ENOG4105CKD	glutathione-regulated potassium-efflux system protein
H3299_RS08030	ENOG4105WJX	transcriptional regulator MERR family
H3299_RS08035	ENOG4108ZUF	This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control (By similarity)
H3299_RS08040	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H3299_RS08070	ENOG4107NKQ	Flavinator of succinate dehydrogenase
H3299_RS08080	ENOG4105CSH	Transporter
H3299_RS08090	ENOG4105CJW	magnesium transporter
H3299_RS08105	ENOG4105CK4	Destroys radicals which are normally produced within the cells and which are toxic to biological systems (By similarity)
H3299_RS08120	ENOG4106PT6	cdpdiacylglycerol-serine O-phosphatidyltransferase
H3299_RS08125	ENOG41071I4	Phosphatidylserine decarboxylase proenzyme
H3299_RS08130	ENOG4108JJ7	ABC transporter
H3299_RS08135	ENOG4108I7Y	domain protein
H3299_RS08140	ENOG4108URH	decarboxylase
H3299_RS08150	ENOG4105C0Q	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity)
H3299_RS08165	ENOG4105CJF	Malonyl coA-acyl carrier protein transacylase
H3299_RS08175	ENOG4105CD3	dihydroorotase
H3299_RS08185	ENOG4108R7K	Metal Dependent Phosphohydrolase
H3299_RS08220	ENOG4105D98	threonine synthase
H3299_RS08235	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
H3299_RS08245	ENOG4105C70	Catalyzes the reversible conversion of 2- phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis (By similarity)
H3299_RS08250	ENOG4108P7N	Exopolysaccharide production negative regulator
H3299_RS08260	ENOG4105DIK	(ABC) transporter
H3299_RS08265	ENOG4105CC5	ABC transporter
H3299_RS08270	ENOG4105CC5	ABC transporter
H3299_RS08275	ENOG4105C2R	Single-stranded-DNA-specific exonuclease (RecJ)
H3299_RS08290	ENOG4108UZ3	Transporter
H3299_RS08300	ENOG4105CEP	NADH dehydrogenase
H3299_RS08305	ENOG4105D29	Helix-turn-helix type 11 domain protein
H3299_RS08325	ENOG4108UQN	AraC family transcriptional regulator
H3299_RS08330	ENOG4105HJX	Biotin- acetyl-CoA-carboxylase ligase
H3299_RS08335	ENOG4105CNR	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H3299_RS08340	ENOG4105C8S	subunit m
H3299_RS08345	ENOG4105D65	subunit l
H3299_RS08350	ENOG4105M5H	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H3299_RS08355	ENOG4105DF2	NADH dehydrogenase subunit j
H3299_RS08360	ENOG4105P3U	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H3299_RS08365	ENOG4105CMZ	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone (By similarity)
H3299_RS08370	ENOG4107R0R	NADH dehydrogenase subunit g
H3299_RS08375	ENOG4107QIZ	NADH dehydrogenase
H3299_RS08380	ENOG4105GKE	subunit e
H3299_RS08385	ENOG4105CQV	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H3299_RS08400	ENOG4105ES3	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient (By similarity)
H3299_RS08405	ENOG4105KWU	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
H3299_RS08435	ENOG4105CEV	competence damage-inducible protein
H3299_RS08510	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
H3299_RS08515	ENOG4107QMH	DNA methylase
H3299_RS08520	ENOG4107J0C	type IIi
H3299_RS08540	ENOG4105FBQ	ATPase associated with various cellular activities aaa_5
H3299_RS08580	ENOG4107QKA	exodeoxyribonuclease V beta
H3299_RS08595	ENOG4108IMY	Transcriptional regulator
H3299_RS08645	ENOG4105CS6	Rhs element vgr protein
H3299_RS08650	ENOG4108WC9	type VI secretion system effector, hcp1 family
H3299_RS08675	ENOG4105CHH	sulfate transporter
H3299_RS08680	ENOG4105CYB	regulatoR
H3299_RS08695	ENOG4105DE7	Sulfate ABC transporter periplasmic sulfate-binding protein
H3299_RS08700	ENOG4108I5D	sulfate abc transporter
H3299_RS08705	ENOG4105ECW	sulfate abc transporter
H3299_RS08710	ENOG4108IJ6	ABC transporter
H3299_RS08720	ENOG4105C7N	Xanthine uracil vitamin C permease
H3299_RS08735	ENOG4105ENX	hydrolase
H3299_RS08740	ENOG4105EQ2	LysR family Transcriptional regulator
H3299_RS08745	ENOG4105ENX	hydrolase
H3299_RS08765	ENOG4105CYM	Glutathione S-transferase
H3299_RS08780	ENOG4105ERG	peptidase m48, ste24p
H3299_RS08795	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
H3299_RS08815	ENOG4105JAB	phenazine biosynthesis protein, phzf family
H3299_RS08825	ENOG4105PGM	cation diffusion facilitator family transporter
H3299_RS08840	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
H3299_RS08860	ENOG41066VF	YeeE YedE family protein
H3299_RS08890	ENOG4105CCZ	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids (By similarity)
H3299_RS08895	ENOG4108V0P	LemA family
H3299_RS08905	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS08910	ENOG4108N53	binding-protein-dependent transport systems inner membrane Component
H3299_RS08955	ENOG4105F87	Dehydratase
H3299_RS08960	ENOG4107QWB	Ornithine cyclodeaminase
H3299_RS08975	ENOG4106TNF	Periplasmic binding protein
H3299_RS08985	ENOG4105E5Q	amino acid AbC transporter
H3299_RS09000	ENOG4105CQ7	ATP-dependent helicase
H3299_RS09030	ENOG4108HRN	Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate (By similarity)
H3299_RS09040	ENOG4105ETT	transcriptional Regulator, LysR family
H3299_RS09055	ENOG4108IJ7	Glycine betaine
H3299_RS09060	ENOG41080HT	Transcriptional regulator, arsr family
H3299_RS09075	ENOG4105DKX	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A) (By similarity)
H3299_RS09100	ENOG4108ZP8	Acetolactate synthase small subunit
H3299_RS09110	ENOG4105DYC	esterase
H3299_RS09115	ENOG4105E0K	tonB-dependent siderophore receptor
H3299_RS09180	ENOG4105C7K	acetolactate synthase
H3299_RS09200	ENOG4105DC7	peptidase M24
H3299_RS09205	ENOG4105EK0	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
H3299_RS09210	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
H3299_RS09225	ENOG4105Q26	Siderophore-interacting protein
H3299_RS09235	ENOG4108QQZ	ErfK YbiS YcfS YnhG family protein
H3299_RS09240	ENOG4105CPF	Cell wall formation (By similarity)
H3299_RS09245	ENOG4108UFP	Essential cell division protein (By similarity)
H3299_RS09250	ENOG4105CIT	This protein may be involved in anomalous filament growth. May be a component of the septum (By similarity)
H3299_RS09255	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
H3299_RS09265	ENOG4105CB8	Multifunctional enzyme that catalyzes the SAM-dependent methylation of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 and then position C-12 or C-18 to form trimethylpyrrocorphin 2. It also catalyzes the conversion of precorrin-2 into siroheme. This reaction consists of the NAD- dependent oxidation of precorrin-2 into sirohydrochlorin and its subsequent ferrochelation into siroheme (By similarity)
H3299_RS09275	ENOG4105ET1	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate (By similarity)
H3299_RS09300	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
H3299_RS09315	ENOG4105CH6	catalase
H3299_RS09325	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
H3299_RS09330	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
H3299_RS09335	ENOG4105BZU	Histidine kinase
H3299_RS09340	ENOG4108UMS	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase (By similarity)
H3299_RS09350	ENOG4105EW9	transcriptional regulator AsnC family
H3299_RS09370	ENOG4107QHU	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity)
H3299_RS09380	ENOG4105CHV	Transcription elongation factor NusA
H3299_RS09385	ENOG4105K7D	Required for maturation of 30S ribosomal subunits (By similarity)
H3299_RS09400	ENOG4105EPW	hflc protein
H3299_RS09405	ENOG4107QJR	hflk protein
H3299_RS09410	ENOG4105C4R	Atp-dependent dna helicase
H3299_RS09420	ENOG4107H9G	Necessary for formate dehydrogenase activity (By similarity)
H3299_RS09425	ENOG4105CXG	d-lactate dehydrogenase
H3299_RS09440	ENOG4105D4A	Cell wall formation (By similarity)
H3299_RS09445	ENOG4105DFU	Cell wall formation (By similarity)
H3299_RS09450	ENOG4105DVQ	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II) (By similarity)
H3299_RS09460	ENOG4105DMZ	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA) (By similarity)
H3299_RS09465	ENOG4105CPY	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan (By similarity)
H3299_RS09475	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
H3299_RS09490	ENOG4105CGJ	Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA (By similarity)
H3299_RS09540	ENOG4105CS6	Rhs element vgr protein
H3299_RS09545	ENOG4108WC9	type VI secretion system effector, hcp1 family
H3299_RS09595	ENOG4105CS6	Rhs element vgr protein
H3299_RS09610	ENOG4108WC9	type VI secretion system effector, hcp1 family
H3299_RS09615	ENOG4105D94	Major Facilitator Superfamily
H3299_RS09630	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
H3299_RS09680	ENOG4105G6Z	alkaline phosphatase
H3299_RS09695	ENOG4108Z8G	Alkylphosphonate utilization operon protein PhnA
H3299_RS09715	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
H3299_RS09720	ENOG4105DMF	Dehydrogenase
H3299_RS09740	ENOG4105C1P	efflux transporter, rnd family, mfp subunit
H3299_RS09745	ENOG4105BZS	acriflavin resistance protein
H3299_RS09750	ENOG4105DEF	Extracellular solute-binding protein, family 5
H3299_RS09755	ENOG4105DEF	Extracellular solute-binding protein, family 5
H3299_RS09765	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
H3299_RS09780	ENOG4105DWF	phosphomethylpyrimidine kinase
H3299_RS09790	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
H3299_RS09810	ENOG4105CIH	Imidazole acetol-phosphate transaminase
H3299_RS09830	ENOG4105DMJ	Catalyzes the transfer of an acetyl group from acetyl- CoA to tetrahydrodipicolinate (By similarity)
H3299_RS09840	ENOG4105DM4	PTS System
H3299_RS09845	ENOG4105DE4	1-phosphofructokinase
H3299_RS09850	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
H3299_RS09855	ENOG4108M60	Transcriptional regulator
H3299_RS09870	ENOG4105DJ2	Major Facilitator Superfamily
H3299_RS09875	ENOG4105FBA	Phospholipase Carboxylesterase
H3299_RS09895	ENOG4105KK3	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
H3299_RS09905	ENOG4105WHM	Necessary for normal cell division and for the maintenance of normal septation (By similarity)
H3299_RS09920	ENOG4108RKI	Necessary for the introduction of cis unsaturation into fatty acids. Catalyzes the dehydration of (3R)-3-hydroxydecanoyl- ACP to E-(2)-decenoyl-ACP and then its isomerization to Z-(3)- decenoyl-ACP. Can catalyze the dehydratase reaction for beta- hydroxyacyl-ACPs with saturated chain lengths up to 16 0, being most active on intermediate chain length (By similarity)
H3299_RS09930	ENOG4105CSJ	Enoyl- acyl-carrier-protein reductase NADH
H3299_RS09935	ENOG4108R5F	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H3299_RS09945	ENOG4105DJ5	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis (By similarity)
H3299_RS09950	ENOG4109003	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis (By similarity)
H3299_RS09960	ENOG4105C9B	Cysteine desulfurase
H3299_RS09965	ENOG4105C3G	gtp-binding protein
H3299_RS09970	ENOG4105C4W	S-formylglutathione hydrolase
H3299_RS09975	ENOG4107QPD	alcohol dehydrogenase
H3299_RS09980	ENOG4105TX3	Histidine kinase
H3299_RS09985	ENOG4108UYB	regulatoR
H3299_RS09990	ENOG4105CZF	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism (By similarity)
H3299_RS09995	ENOG4105VKD	bioY protein
H3299_RS10000	ENOG4108UHE	carbonic anhydrase
H3299_RS10005	ENOG4105DWH	electron transfer flavoprotein-ubiquinone oxidoreductase
H3299_RS10015	ENOG4107R6G	Catalyzes the S-adenosylmethionine monomethyl esterification of trans-aconitate (By similarity)
H3299_RS10020	ENOG4108VDT	Glycosyl transferase family protein
H3299_RS10025	ENOG4105CHR	reductase
H3299_RS10040	ENOG4105VMP	Transcriptional regulator
H3299_RS10055	ENOG4105E0A	ABC, transporter
H3299_RS10060	ENOG4105EHG	Permease protein
H3299_RS10065	ENOG4105S10	periplasmic binding protein
H3299_RS10070	ENOG4108VJC	ABC transporter, periplasmic molybdate-binding protein
H3299_RS10080	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3299_RS10085	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
H3299_RS10095	ENOG4105CUY	Mechanosensitive ion channel
H3299_RS10100	ENOG4105CJ9	Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (By similarity)
H3299_RS10105	ENOG4105K5Y	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (By similarity)
H3299_RS10120	ENOG4105ETE	Transcriptional regulator (LacI family
H3299_RS10135	ENOG4105CIS	alcohol dehydrogenase
H3299_RS10140	ENOG4105CIS	alcohol dehydrogenase
H3299_RS10160	ENOG4105C6K	Malic enzyme
H3299_RS10165	ENOG4105CE7	Amidase, hydantoinase carbamoylase family
H3299_RS10170	ENOG4105CD3	dihydroorotase
H3299_RS10205	ENOG4105K90	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
H3299_RS10215	ENOG4105CC0	LysR family Transcriptional regulator
H3299_RS10230	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3299_RS10235	ENOG4107QJQ	Mate efflux family protein
H3299_RS10240	ENOG4105C01	Dihydroxy-acid dehydratase
H3299_RS10245	ENOG4105C91	Plays an important role in the de novo pathway of purine nucleotide biosynthesis
H3299_RS10250	ENOG4108IJ6	ABC transporter
H3299_RS10255	ENOG4105ECW	sulfate abc transporter
H3299_RS10260	ENOG4108I5D	sulfate abc transporter
H3299_RS10265	ENOG4108J2H	Sulfate ABC transporter periplasmic sulfate-binding protein
H3299_RS10275	ENOG4105GBT	ABC transporter
H3299_RS10285	ENOG4105CDA	abc transporter atp-binding protein
H3299_RS10290	ENOG4106EG9	Catalyzes the decarboxylation of orotidine 5'- monophosphate (OMP) to uridine 5'-monophosphate (UMP) (By similarity)
H3299_RS10295	ENOG4105CYC	Transferase
H3299_RS10310	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
H3299_RS10320	ENOG4107QM9	Component of the acetyl coenzyme A carboxylase (ACC) complex. First, biotin carboxylase catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the carboxyltransferase to acetyl-CoA to form malonyl-CoA (By similarity)
H3299_RS10335	ENOG4105D49	3-dehydroquinate synthase
H3299_RS10355	ENOG4105CH2	amidohydrolase
H3299_RS10360	ENOG4105CSH	Transporter
H3299_RS10375	ENOG4105D43	The glycine cleavage system catalyzes the degradation of glycine (By similarity)
H3299_RS10380	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
H3299_RS10385	ENOG4105CBI	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
H3299_RS10410	ENOG4105CHB	tonB-dependent Receptor
H3299_RS10420	ENOG4105CUB	amino acid
H3299_RS10425	ENOG4108JPX	Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor (By similarity)
H3299_RS10430	ENOG4105DV0	amidase (EC 3.5.1.4
H3299_RS10445	ENOG4105CUJ	penicillin amidase
H3299_RS10450	ENOG4107S4Y	M20 DapE family protein YgeY
H3299_RS10455	ENOG4105CH2	amidohydrolase
H3299_RS10485	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
H3299_RS10490	ENOG4105CF4	DegT DnrJ EryC1 StrS aminotransferase
H3299_RS10505	ENOG4105CAS	nag kinase
H3299_RS10535	ENOG4107QN1	sodium solute
H3299_RS10545	ENOG4108W2Y	isochorismatase
H3299_RS10570	ENOG4105CV8	reductase
H3299_RS10605	ENOG4105CDH	Citrulline--aspartate ligase
H3299_RS10610	ENOG4108HPI	phosphatidate Cytidylyltransferase
H3299_RS10620	ENOG41077RS	Phosphatase
H3299_RS10625	ENOG4105E8V	Alpha Beta Hydrolase Fold protein
H3299_RS10630	ENOG4108UMZ	Cdp-alcohol phosphatidyltransferase
H3299_RS10640	ENOG4105CSH	Transporter
H3299_RS10655	ENOG4105DBV	ornithine carbamoyltransferase
H3299_RS10660	ENOG4105C8Y	Acetylornithine aminotransferase
H3299_RS10680	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H3299_RS10720	ENOG4107EEK	Catalyzes the decarboxylative condensation of pimeloyl- acyl-carrier protein and L-alanine to produce 8-amino-7- oxononanoate (AON), acyl-carrier protein , and carbon dioxide (By similarity)
H3299_RS10755	ENOG4105DRH	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase (By similarity)
H3299_RS10760	ENOG4105ECY	inositol monophosphatase
H3299_RS10790	ENOG4105CJT	Mannose-1-phosphate guanylyltransferase
H3299_RS10795	ENOG4105C2W	permease
H3299_RS10815	ENOG4105M6F	mutator MutT protein
H3299_RS10820	ENOG4108RTV	Catalyzes the transfer of acetyl from acetyl-CoA to desacetylmycothiol (Cys-GlcN-Ins) to form mycothiol (By similarity)
H3299_RS10825	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
H3299_RS10840	ENOG4108MG3	formate dehydrogenase
H3299_RS10845	ENOG4105QA4	4Fe-4S Ferredoxin, iron-sulfur binding domain protein
H3299_RS10870	ENOG4107N1Q	ErfK YbiS YcfS YnhG family protein
H3299_RS10880	ENOG4105D05	Receptor
H3299_RS10885	ENOG4105CV8	reductase
H3299_RS10915	ENOG4108YYC	ycei family
H3299_RS10920	ENOG4107QTG	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA (By similarity)
H3299_RS10940	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
H3299_RS10945	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H3299_RS10980	ENOG4108RWI	nicotinamidase
H3299_RS11015	ENOG4105C3R	Methionine synthase
H3299_RS11025	ENOG4105CGT	Catalyzes the transfer of a phosphate group to glutamate to form glutamate 5-phosphate which rapidly cyclizes to 5- oxoproline (By similarity)
H3299_RS11035	ENOG4107WK2	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
H3299_RS11050	ENOG4108UXA	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA (By similarity)
H3299_RS11055	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
H3299_RS11075	ENOG4108ZZF	transport protein (ExbD)
H3299_RS11085	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS11100	ENOG4105DRS	transport system, permease
H3299_RS11125	ENOG4105CDA	abc transporter atp-binding protein
H3299_RS11155	ENOG4105C0H	protease
H3299_RS11165	ENOG4105VIG	Sec-independent protein translocase protein TatC
H3299_RS11175	ENOG4107RFD	Non-specific O-methyltransferase that catalyzes the 2 O- methylation steps in the ubiquinone biosynthetic pathway (By similarity)
H3299_RS11195	ENOG4105C7P	2-oxoglutarate dehydrogenase, E1
H3299_RS11200	ENOG4105C7S	Dehydrogenase
H3299_RS11235	ENOG4108RW0	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid (By similarity)
H3299_RS11245	ENOG4105FF5	Membrane
H3299_RS11290	ENOG4107TJ9	Cytochrome
H3299_RS11295	ENOG4105HRV	phosphonate c-p lyase system protein phnl
H3299_RS11300	ENOG4105ENV	phosphonate C-P lyase system protein PhnK
H3299_RS11325	ENOG4107RJJ	Transcriptional regulator
H3299_RS11330	ENOG4105D5T	phosphonate abc transporter
H3299_RS11335	ENOG4105EHI	Phosphonate ABC transporter, periplasmic
H3299_RS11345	ENOG4108TXN	phosphonate metabolism protein
H3299_RS11350	ENOG4105FD8	phosphonate metabolism protein PhnM
H3299_RS11380	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H3299_RS11390	ENOG4108NH8	Cation transport protein
H3299_RS11440	ENOG4105CS6	Rhs element vgr protein
H3299_RS11445	ENOG4108WC9	type VI secretion system effector, hcp1 family
H3299_RS11450	ENOG4105DEK	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
H3299_RS11475	ENOG4108ETY	sodium dicarboxylate symporter
H3299_RS11480	ENOG4105C4G	Synthesis of 3-octaprenyl-4-hydroxybenzoate (By similarity)
H3299_RS11495	ENOG4105D37	Low-affinity potassium transport system. Interacts with Trk system potassium uptake protein TrkA (By similarity)
H3299_RS11515	ENOG4105P69	integral membrane protein
H3299_RS11520	ENOG4105F4R	Transcriptional regulator mode
H3299_RS11525	ENOG4108S6J	ABC transporter, periplasmic molybdate-binding protein
H3299_RS11530	ENOG4105E0C	molybdate abc transporter
H3299_RS11535	ENOG4105CGB	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS11540	ENOG4105VEJ	Heat shock protein
H3299_RS11550	ENOG41082R8	50S ribosomal protein l32
H3299_RS11560	ENOG4105CTB	Polyprenyl synthetase
H3299_RS11590	ENOG4105CMI	transporter
H3299_RS11595	ENOG4105CJ1	ABC, transporter
H3299_RS11600	ENOG4105D0S	secretion protein (HlyD
H3299_RS11605	ENOG4105E0F	Histidine kinase
H3299_RS11610	ENOG4105DPZ	Two component transcriptional regulator (Winged helix family
H3299_RS11615	ENOG41090HR	transcriptional regulator
H3299_RS11620	ENOG4105C5X	domain protein
H3299_RS11625	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
H3299_RS11630	ENOG4105CDY	transcriptional regulatory protein
H3299_RS11635	ENOG4107ZYJ	bioY protein
H3299_RS11665	ENOG4105E0F	Histidine kinase
H3299_RS11685	ENOG4105EXC	Acyl-transferase
H3299_RS11690	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H3299_RS11695	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H3299_RS11700	ENOG4105C3U	ABC transporter
H3299_RS11705	ENOG4108JQ7	(ABC) transporter
H3299_RS11710	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
H3299_RS11750	ENOG4105C0P	Mg chelatase subunit ChlI
H3299_RS11755	ENOG4105CFU	surface antigen
H3299_RS11765	ENOG4105DVC	DnaJ domain protein
H3299_RS11795	ENOG4105C3B	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins (By similarity)
H3299_RS11805	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
H3299_RS11820	ENOG4108Z7R	Chaperone CsaA
H3299_RS11825	ENOG41063V1	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid (By similarity)
H3299_RS11835	ENOG4108ZTZ	UPF0262 protein
H3299_RS11855	ENOG4107ZDE	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
H3299_RS11860	ENOG4105C4J	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits (By similarity)
H3299_RS11865	ENOG4105J80	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex (By similarity)
H3299_RS11885	ENOG4105C62	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3'- to 5'-direction (By similarity)
H3299_RS11890	ENOG4108Z4U	Ferredoxin
H3299_RS11900	ENOG4105CHH	sulfate transporter
H3299_RS11910	ENOG4105C0C	Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity)
H3299_RS11920	ENOG4105C3M	thioredoxin reductase
H3299_RS11925	ENOG4105CBN	LysR family transcriptional regulator
H3299_RS11965	ENOG4105CN1	protease
H3299_RS11980	ENOG4105C29	acyl-CoA thioesterase
H3299_RS12015	ENOG4105CKU	formyltetrahydrofolate synthetase
H3299_RS12020	ENOG4105W49	UPF0434 protein
H3299_RS12025	ENOG4105C6P	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner (By similarity)
H3299_RS12030	ENOG4105DKK	Benzoate
H3299_RS12050	ENOG4106H78	methyltransferase
H3299_RS12095	ENOG4105CH2	amidohydrolase
H3299_RS12100	ENOG4105DHP	deoxycytidine triphosphate deaminase
H3299_RS12140	ENOG4105CJP	fad dependent oxidoreductase
H3299_RS12145	ENOG4105CFQ	glutamine synthetase
H3299_RS12230	ENOG4105E39	Enoyl-CoA hydratase
H3299_RS12245	ENOG4105C1Y	Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis (By similarity)
H3299_RS12255	ENOG4107J0A	lipopolysaccharide biosynthetic process
H3299_RS12260	ENOG4107QRT	dEAD DEAH box helicase
H3299_RS12265	ENOG4105EQ2	LysR family Transcriptional regulator
H3299_RS12365	ENOG4108N0N	Phage Terminase Large Subunit
H3299_RS12390	ENOG4105CPC	Aldo Keto reductase
H3299_RS12395	ENOG4108DN8	FAD dependent oxidoreductase
H3299_RS12420	ENOG4105CHI	Involved in the active translocation of vitamin B12 (cyanocobalamin) across the outer membrane to the periplasmic space. It derives its energy for transport by interacting with the trans-periplasmic membrane protein TonB (By similarity)
H3299_RS12430	ENOG4105EHG	Permease protein
H3299_RS12435	ENOG4105E0A	ABC, transporter
H3299_RS12480	ENOG4106XMA	In vivo, quickly hydrolyzes the ureidoacrylate peracid to avoid toxicity, but can also hydrolyzes ureidoacrylate that is formed spontaneously from ureidoacrylate peracid. One of the products of hydrolysis, carbamate, hydrolyzes spontaneously, thereby releasing one of the pyrimidine rings nitrogen atoms as ammonia and one of its carbons as CO2 (By similarity)
H3299_RS12490	ENOG4105II7	pyrroline-5-carboxylate reductase
H3299_RS12505	ENOG4105BZU	Histidine kinase
H3299_RS12520	ENOG4105ECY	inositol monophosphatase
H3299_RS12555	ENOG4105ETE	Transcriptional regulator (LacI family
H3299_RS12560	ENOG4105C6Q	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
H3299_RS12565	ENOG4107UEK	pfkb domain protein
H3299_RS12570	ENOG4105CNN	ABC, transporter
H3299_RS12580	ENOG4105DFW	ABC transporter
H3299_RS12590	ENOG4105C4R	Atp-dependent dna helicase
H3299_RS12610	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
H3299_RS12615	ENOG4105E33	succinate dehydrogenase
H3299_RS12630	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
H3299_RS12635	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
H3299_RS12640	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS12650	ENOG4105C8U	phosphate abc transporter
H3299_RS12660	ENOG4105D7Z	glutathione synthase
H3299_RS12665	ENOG4105D06	uba thif-type nad fad binding protein
H3299_RS12670	ENOG4108RVA	ribokinase
H3299_RS12705	ENOG4105D0M	Protease HtpX homolog
H3299_RS12710	ENOG4105CYJ	ribosomal RNA small subunit methyltransferase B
H3299_RS12720	ENOG4105C88	aminopeptidase
H3299_RS12725	ENOG4105ERD	Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates (By similarity)
H3299_RS12730	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
H3299_RS12745	ENOG4108JQ5	ABC transporter
H3299_RS12750	ENOG4108IYQ	Binding-protein-dependent transport systems inner membrane component
H3299_RS12755	ENOG4108I5X	binding-protein-dependent transport systems inner membrane Component
H3299_RS12765	ENOG4105G9V	cytochrome C
H3299_RS12785	ENOG4105K4I	Scp-like extracellular
H3299_RS12795	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
H3299_RS12800	ENOG41082BR	50S ribosomal protein L35
H3299_RS12805	ENOG4108YZX	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit (By similarity)
H3299_RS12815	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
H3299_RS12820	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
H3299_RS12845	ENOG4107QM5	aconitate hydratase
H3299_RS12850	ENOG4107EV4	once thought to export heme, this seems not to be the case, but its exact role is uncertain. Responsible for energy coupling to the transport system (By similarity)
H3299_RS12855	ENOG4105CA5	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes (By similarity)
H3299_RS12860	ENOG41060IM	Heme exporter protein
H3299_RS12870	ENOG4107QX9	Thiol disulfide interChange protein
H3299_RS12945	ENOG4105R5N	Phosphoribosyl-dephospho-CoA transferase
H3299_RS12955	ENOG4108459	Subunit of malonate decarboxylase, it is an acyl carrier protein to which acetyl and malonyl thioester residues are bound via a 2'-(5''-phosphoribosyl)-3'-dephospho-CoA prosthetic group and turn over during the catalytic mechanism (By similarity)
H3299_RS12975	ENOG4105DRR	Transcriptional regulator, GntR family
H3299_RS12985	ENOG4105DEG	Vwa containing coxe family protein
H3299_RS12995	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
H3299_RS13000	ENOG4108KDT	Molybdate metabolism regulator
H3299_RS13005	ENOG4108KDT	Molybdate metabolism regulator
H3299_RS13010	ENOG4108KDT	Molybdate metabolism regulator
H3299_RS13030	ENOG4108KDT	Molybdate metabolism regulator
H3299_RS13070	ENOG4105CS6	Rhs element vgr protein
H3299_RS13130	ENOG4105E6K	4-Hydroxyphenylpyruvate dioxygenase
H3299_RS13135	ENOG4105CHU	acetyl-coa acetyltransferase
H3299_RS13140	ENOG4107QNJ	CoA-transferase subunit B
H3299_RS13150	ENOG4105CSH	Transporter
H3299_RS13180	ENOG4105F0N	pyrophosphate phospho-hydrolase
H3299_RS13185	ENOG4105CI3	gtp-binding protein typa
H3299_RS13190	ENOG4105D4F	Synthesizes selenophosphate from selenide and ATP (By similarity)
H3299_RS13195	ENOG4105D48	metallophosphoesterase
H3299_RS13215	ENOG4105DFA	alanine racemase domain protein
H3299_RS13220	ENOG4105C8T	Leucyl-tRNA synthetase
H3299_RS13235	ENOG4105M0T	TPR Repeat-Containing Protein
H3299_RS13245	ENOG4105MK2	5-formyltetrahydrofolate cyclo-ligase
H3299_RS13260	ENOG4107QWE	)-transporter
H3299_RS13305	ENOG4107YTN	Specifically methylates the N7 position of guanine in position 527 of 16S rRNA (By similarity)
H3299_RS13310	ENOG4107RE5	NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34 (By similarity)
H3299_RS13315	ENOG4105C1H	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34 (By similarity)
H3299_RS13320	ENOG4105C4P	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template (By similarity)
H3299_RS13325	ENOG4105YVS	arsR family transcriptional regulator
H3299_RS13335	ENOG4105C2M	dna polymerase I
H3299_RS13340	ENOG4108YXA	Membrane
H3299_RS13350	ENOG4105CF9	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation dephosphorylation (By similarity)
H3299_RS13360	ENOG4105CKI	cobalamin synthesis protein
H3299_RS13370	ENOG4105DEF	Extracellular solute-binding protein, family 5
H3299_RS13375	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
H3299_RS13380	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H3299_RS13385	ENOG4108JQ6	ABC transporter
H3299_RS13410	ENOG4108RNI	3'(2')5'-bisphosphate nucleotidase
H3299_RS13415	ENOG4105CMS	peptidase U62, modulator of DNA gyrase
H3299_RS13425	ENOG4105C59	p-type ATPase
H3299_RS13450	ENOG4105C2I	pirin domain protein
H3299_RS13475	ENOG4108ESX	Receptor
H3299_RS13485	ENOG4105ZDB	Protein slyX homolog
H3299_RS13515	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
H3299_RS13525	ENOG4105WD1	Membrane
H3299_RS13530	ENOG4105VDW	Csbd family
H3299_RS13545	ENOG4106PGW	Short-chain dehydrogenase reductase Sdr
H3299_RS13550	ENOG4105E7Q	Cob(II)yrinic acid a,c-diamide reductase
H3299_RS13565	ENOG4105M7V	2'-5' rna ligase
H3299_RS13585	ENOG4105MWK	D-amino acid dehydrogenase, small subunit
H3299_RS13590	ENOG4107R4I	Periplasmic binding protein
H3299_RS13610	ENOG4105D38	putrescine abc transporter
H3299_RS13615	ENOG4105F38	ABC transporter, permease
H3299_RS13620	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS13625	ENOG4108HM4	ABC transporter
H3299_RS13650	ENOG4107QXP	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
H3299_RS13655	ENOG4105CI6	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving
H3299_RS13680	ENOG4107ZQV	short-chain dehydrogenase reductase
H3299_RS13685	ENOG4105D8W	glucose-6-phosphate 1-dehydrogenase
H3299_RS13690	ENOG4108Q79	6-phosphogluconolactonase (EC 3.1.1.31)
H3299_RS13695	ENOG4105E2V	Glycosyltransferase 36
H3299_RS13700	ENOG4107RZZ	dna polymerase iii epsilon subunit
H3299_RS13705	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
H3299_RS13710	ENOG4105E2X	shikimate dehydrogenase
H3299_RS13715	ENOG4108UHJ	MAF-like protein
H3299_RS13750	ENOG41066UZ	arginase EC 3.5.3.1
H3299_RS13755	ENOG4105EA8	2-Nitropropane dioxygenase
H3299_RS13780	ENOG4105KKX	ATPase associated with various cellular activities aaa_5
H3299_RS13785	ENOG4105RD5	
H3299_RS13790	ENOG4105DEG	Vwa containing coxe family protein
H3299_RS13805	ENOG4105CHR	reductase
H3299_RS13810	ENOG4105CHR	reductase
H3299_RS13825	ENOG4105HDK	L-asparaginase
H3299_RS13840	ENOG4105D3D	Catalyzes the decarboxylation of carboxynorspermidine and carboxyspermidine (By similarity)
H3299_RS13855	ENOG4105F4R	Transcriptional regulator mode
H3299_RS13860	ENOG4105EQ2	LysR family Transcriptional regulator
H3299_RS13870	ENOG4108ZNX	Heat shock protein
H3299_RS13880	ENOG4108TEB	UPF0114 protein
H3299_RS13900	ENOG4105UXD	Outer membrane lipoprotein
H3299_RS13905	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
H3299_RS13910	ENOG4105CIW	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine (By similarity)
H3299_RS13915	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
H3299_RS13945	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
H3299_RS13960	ENOG4105BZU	Histidine kinase
H3299_RS13965	ENOG4108ZXC	Two component transcriptional regulator, luxr family
H3299_RS13970	ENOG4108JBU	Outer membrane protein Omp31
H3299_RS13985	ENOG4105DP0	ferredoxin-NADP reductase
H3299_RS13990	ENOG4106ECQ	phosphomannomutase
H3299_RS13995	ENOG4107R6Y	Involved in the TonB-independent uptake of proteins (By similarity)
H3299_RS14040	ENOG4105D1E	Undecaprenyl pyrophosphate phosphatase
H3299_RS14060	ENOG4105CZ5	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate (By similarity)
H3299_RS14065	ENOG4105DDZ	Methyltransferase required for the conversion of demethylmenaquinone (DMKH2) to menaquinone (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) (By similarity)
H3299_RS14070	ENOG4105CNK	Required, probably indirectly, for the hydroxylation of 2-octaprenylphenol to 2-octaprenyl-6-hydroxy-phenol, the fourth step in ubiquinone biosynthesis (By similarity)
H3299_RS14080	ENOG4105DR5	peptidase
H3299_RS14120	ENOG4105JSC	dimethylmenaquinone methyltransferase
H3299_RS14140	ENOG4105BZC	d-serine deaminase
H3299_RS14230	ENOG4107QKW	extracellular solute-binding protein family 1
H3299_RS14235	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
H3299_RS14265	ENOG4108IND	Tetr family transcriptional regulator
H3299_RS14275	ENOG4108JJB	ABC transporter
H3299_RS14295	ENOG4105C5H	ABC transporter
H3299_RS14300	ENOG4107ZT5	Thiol disulfide interchange protein
H3299_RS14335	ENOG4105F0N	pyrophosphate phospho-hydrolase
H3299_RS14340	ENOG4105E09	nadh pyrophosphatase
H3299_RS14355	ENOG4107QMP	dna polymerase iii subunits gamma and tau
H3299_RS14360	ENOG4105KDX	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection (By similarity)
H3299_RS14365	ENOG4105CHU	acetyl-coa acetyltransferase
H3299_RS14370	ENOG4105FDP	GntR family transcriptional regulator
H3299_RS14375	ENOG4105D5U	fad dependent oxidoreductase
H3299_RS14400	ENOG4105DDW	LysR family Transcriptional regulator
H3299_RS14405	ENOG4105F2Z	3-oxoadipate enol-lactonase
H3299_RS14410	ENOG4108UWZ	4-Carboxymuconolactone decarboxylase
H3299_RS14415	ENOG4105EU7	Protocatechuate 3,4-dioxygenase, beta
H3299_RS14420	ENOG4105RM9	Protocatechuate 3,4-dioxygenase alpha
H3299_RS14425	ENOG4105E2X	shikimate dehydrogenase
H3299_RS14435	ENOG4105DRI	Involved in the oxidation of myo-inositol (MI) to 2- keto-myo-inositol (2KMI or 2-inosose) (By similarity)
H3299_RS14440	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H3299_RS14445	ENOG4105DAB	fumarate reductase succinate dehydrogenase flavoprotein domain protein
H3299_RS14455	ENOG41063SR	receptor
H3299_RS14480	ENOG4105KK9	This protein binds to 23S rRNA in the presence of protein L20 (By similarity)
H3299_RS14485	ENOG4105K46	50S ribosomal protein l27
H3299_RS14525	ENOG41060GT	Translocates 4-amino-4-deoxy-L-arabinose- phosphoundecaprenol (alpha-L-Ara4N-phosphoundecaprenol) from the cytoplasmic to the periplasmic side of the inner membrane (By similarity)
H3299_RS14540	ENOG4107EXC	regulatoR
H3299_RS14545	ENOG4105BZU	Histidine kinase
H3299_RS14555	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
H3299_RS14560	ENOG4108URP	Dtdp-4-dehydrorhamnose 3,5-epimerase
H3299_RS14565	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
H3299_RS14580	ENOG4107RBI	VanW family
H3299_RS14665	ENOG4105YAJ	CopG Arc MetJ
H3299_RS14670	ENOG4105C6V	Glycerol-3-phosphate dehydrogenase
H3299_RS14675	ENOG4108KAZ	Involved in phosphonate degradation (By similarity)
H3299_RS14680	ENOG4105C87	Aminotransferase class I and II
H3299_RS14685	ENOG4105C44	Serine transporter
H3299_RS14690	ENOG4105CGF	Aromatic amino acid aminotransferase
H3299_RS14710	ENOG4108JPW	Aminotransferase
H3299_RS14730	ENOG4105CK0	Membrane bOund o-acyl transferase mboat family protein
H3299_RS14755	ENOG4107U7B	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine (By similarity)
H3299_RS14765	ENOG4105E0X	reductase
H3299_RS14770	ENOG4105C85	amino acid
H3299_RS14810	ENOG4108TZY	GntR Family Transcriptional Regulator
H3299_RS14825	ENOG4105C7J	ABC transporter, permease
H3299_RS14835	ENOG4105C0R	drug resistance transporter emrb qaca subfamily
H3299_RS14860	ENOG4105C84	Histidine ammonia-lyase
H3299_RS14865	ENOG4105CI2	imidazolone-5-propionate hydrolase
H3299_RS14890	ENOG4105VKD	bioY protein
H3299_RS14900	ENOG4105D7T	ABC transporter
H3299_RS14905	ENOG4105I5W	Transporter
H3299_RS14910	ENOG4105DG7	nitrate ABC transporter
H3299_RS14960	ENOG4105DN3	alpha-2-macroglobulin domain protein
H3299_RS14965	ENOG4108JQB	penicillin-binding protein 1C
H3299_RS15010	ENOG4105UNS	Pfam:DUF419
H3299_RS15030	ENOG4105DXI	Major Facilitator superfamily
H3299_RS15045	ENOG4105DCT	glycerol dehydrogenase
H3299_RS15055	ENOG4105CYX	Short-chain dehydrogenase reductase Sdr
H3299_RS15075	ENOG4105D9N	nucleoside
H3299_RS15080	ENOG4105D53	Catalyzes the hydrolysis of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil (By similarity)
H3299_RS15085	ENOG4105DD7	kinase (PfkB family
H3299_RS15125	ENOG4108UQD	Sel1 domain protein repeat-containing protein
H3299_RS15135	ENOG4105CPQ	Dehydrogenase
H3299_RS15140	ENOG4105CFF	transcriptional regulator
H3299_RS15145	ENOG4107QX3	carboxylase
H3299_RS15175	ENOG4108IQF	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA (By similarity)
H3299_RS15205	ENOG4105CSH	Transporter
H3299_RS15210	ENOG4105CYW	agmatinase
H3299_RS15215	ENOG4107S4Y	M20 DapE family protein YgeY
H3299_RS15225	ENOG4105CSH	Transporter
H3299_RS15230	ENOG4107YNJ	LysR family Transcriptional regulator
H3299_RS15240	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
H3299_RS15285	ENOG4105CW3	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
H3299_RS15295	ENOG4105DSE	periplasmic solute binding protein
H3299_RS15300	ENOG4105CC5	ABC transporter
H3299_RS15305	ENOG4105DIK	(ABC) transporter
H3299_RS15430	ENOG4105VTW	prevent-host-death family
H3299_RS15435	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
H3299_RS15485	ENOG4105X54	addiction module antidote protein
H3299_RS15515	ENOG4108M24	von Willebrand factor, type A
H3299_RS15545	ENOG41089I4	Inherit from COG: Glycosyl transferase, family 2