locus-tag	class	description
LBE40_RS00015	COG2885	chlorophyll binding
LBE40_RS00025	COG0037	tRNA processing
LBE40_RS00030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
LBE40_RS00035	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
LBE40_RS00055	COG0848	biopolymer transport protein
LBE40_RS00060	COG0756	dUTP diphosphatase activity
LBE40_RS00090	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LBE40_RS00245	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
LBE40_RS00250	COG1396	sequence-specific DNA binding
LBE40_RS00255	COG1692	metallophosphoesterase
LBE40_RS00265	COG0534	Mate efflux family protein
LBE40_RS00280	COG0257	Belongs to the bacterial ribosomal protein bL36 family
LBE40_RS00285	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
LBE40_RS00290	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
LBE40_RS00295	COG1396	sequence-specific DNA binding
LBE40_RS00305	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LBE40_RS00320	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LBE40_RS00345	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
LBE40_RS00350	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
LBE40_RS00355	COG0424	maF-like protein
LBE40_RS00360	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
LBE40_RS00465	COG0784	Response regulator, receiver
LBE40_RS00480	COG3920	Histidine kinase
LBE40_RS00530	COG3403	YqcI/YcgG family
LBE40_RS00555	COG0284	orotidine-5'-phosphate decarboxylase activity
LBE40_RS00560	COG0124	histidyl-tRNA synthetase
LBE40_RS00570	COG0033	Phosphoglucomutase
LBE40_RS00580	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
LBE40_RS00585	COG0459	protein refolding
LBE40_RS00590	COG1396	sequence-specific DNA binding
LBE40_RS00595	COG2824	Alkylphosphonate utilization operon protein PhnA
LBE40_RS00600	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
LBE40_RS00620	COG0180	Tryptophanyl-tRNA synthetase
LBE40_RS00625	COG0728	peptidoglycan biosynthetic process
LBE40_RS00630	COG2184	nucleotidyltransferase activity
LBE40_RS00645	COG2184	nucleotidyltransferase activity
LBE40_RS00655	COG3505	Type IV secretory pathway VirD4
LBE40_RS00660	COG2184	nucleotidyltransferase activity
LBE40_RS00670	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
LBE40_RS00675	COG2948	multi-organism process
LBE40_RS00680	COG3504	Conjugal transfer protein
LBE40_RS00685	COG3736	Type IV secretory pathway, component VirB8
LBE40_RS00695	COG3704	protein secretion by the type IV secretion system
LBE40_RS00705	COG3451	type IV secretory pathway VirB4
LBE40_RS00710	COG3702	type iv secretory pathway
LBE40_RS00715	COG3838	Conjugal transfer protein Trbc
LBE40_RS00745	COG0196	riboflavin kinase activity
LBE40_RS00755	COG1192	Involved in chromosome partitioning
LBE40_RS00810	COG4604	ABC transporter, ATP-binding protein
LBE40_RS00815	COG4605	iron ion homeostasis
LBE40_RS00820	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LBE40_RS00825	COG4607	ABC-type enterochelin transport system periplasmic component
LBE40_RS00890	COG0523	cobalamin synthesis protein
LBE40_RS00915	COG2011	ABC-type metal ion transport system permease component
LBE40_RS00920	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
LBE40_RS00935	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
LBE40_RS00940	COG1396	sequence-specific DNA binding
LBE40_RS00955	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
LBE40_RS00960	COG2835	tetraacyldisaccharide 4'-kinase activity
LBE40_RS00965	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
LBE40_RS00970	COG0404	The glycine cleavage system catalyzes the degradation of glycine
LBE40_RS00975	COG0509	glycine decarboxylation via glycine cleavage system
LBE40_RS00980	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LBE40_RS00980	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
LBE40_RS00995	COG0800	Aldolase
LBE40_RS01000	COG1054	Belongs to the UPF0176 family
LBE40_RS01025	COG0735	belongs to the Fur family
LBE40_RS01075	COG2814	Major facilitator Superfamily
LBE40_RS01085	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
LBE40_RS01085	COG0473	3-isopropylmalate dehydrogenase activity
LBE40_RS01090	COG3023	N-Acetylmuramoyl-L-alanine amidase
LBE40_RS01110	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
LBE40_RS01120	COG0588	phosphoglycerate mutase activity
LBE40_RS01125	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
LBE40_RS01135	COG0218	Necessary for normal cell division and for the maintenance of normal septation
LBE40_RS01145	COG0594	ribonuclease P activity
LBE40_RS01150	COG0230	Belongs to the bacterial ribosomal protein bL34 family
LBE40_RS01155	COG0489	protein tyrosine kinase activity
LBE40_RS01160	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
LBE40_RS01165	COG0792	nuclease activity
LBE40_RS01190	COG2086	electron transfer activity
LBE40_RS01200	COG0730	response to heat
LBE40_RS01220	COG0747	negative chemotaxis
LBE40_RS01230	COG1570	exodeoxyribonuclease VII activity
LBE40_RS01235	COG0519	Catalyzes the synthesis of GMP from XMP
LBE40_RS01270	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
LBE40_RS01360	COG0482	sulfurtransferase activity
LBE40_RS01370	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
LBE40_RS01395	COG0714	Associated with various cellular activities
LBE40_RS01400	COG0617	tRNA 3'-terminal CCA addition
LBE40_RS01405	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
LBE40_RS01420	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
LBE40_RS01420	COG2857	Cytochrome c1
LBE40_RS01430	COG0012	GTP binding
LBE40_RS01435	COG1376	ErfK ybiS ycfS ynhG family protein
LBE40_RS01440	COG0193	aminoacyl-tRNA hydrolase activity
LBE40_RS01445	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
LBE40_RS01460	COG1496	oxidoreductase activity
LBE40_RS01470	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
LBE40_RS01485	COG2205	protein histidine kinase activity
LBE40_RS01490	COG0745	RESPONSE REGULATOR receiver
LBE40_RS01495	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBE40_RS01520	COG0556	nucleotide-excision repair
LBE40_RS01530	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
LBE40_RS01540	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
LBE40_RS01545	COG0492	ferredoxin-NADP+ reductase activity
LBE40_RS01550	COG0583	DNA-binding transcription factor activity
LBE40_RS01555	COG0436	Aminotransferase
LBE40_RS01560	COG1278	Cold shock
LBE40_RS01580	COG0505	Belongs to the CarA family
LBE40_RS01585	COG3161	chorismate lyase activity
LBE40_RS01600	COG0668	transmembrane transport
LBE40_RS01610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LBE40_RS01615	COG2983	Belongs to the UPF0260 family
LBE40_RS01620	COG2968	Membrane
LBE40_RS01670	COG1335	isochorismatase
LBE40_RS01685	COG2226	methyltransferase
LBE40_RS01695	COG0741	lytic transglycosylase activity
LBE40_RS01705	COG0275	rRNA processing
LBE40_RS01710	COG5462	secreted (periplasmic) protein
LBE40_RS01720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
LBE40_RS01730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
LBE40_RS01735	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
LBE40_RS01745	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
LBE40_RS01750	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
LBE40_RS01755	COG0812	UDP-N-acetylmuramate dehydrogenase activity
LBE40_RS01760	COG1181	Belongs to the D-alanine--D-alanine ligase family
LBE40_RS01770	COG0849	cell division
LBE40_RS01785	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
LBE40_RS01790	COG0497	DNA recombination
LBE40_RS01795	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LBE40_RS01800	COG0006	proline dipeptidase activity
LBE40_RS01810	COG1999	signal sequence binding
LBE40_RS01820	COG0210	DNA helicase
LBE40_RS01850	COG0477	Major facilitator Superfamily
LBE40_RS01855	COG0477	Major facilitator Superfamily
LBE40_RS01860	COG0477	Major facilitator Superfamily
LBE40_RS01865	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
LBE40_RS01885	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LBE40_RS01890	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
LBE40_RS01895	COG0028	Belongs to the TPP enzyme family
LBE40_RS01910	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LBE40_RS01915	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
LBE40_RS01930	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
LBE40_RS01935	COG1113	amino acid transport
LBE40_RS01940	COG1280	lysine exporter protein (LysE YggA)
LBE40_RS01950	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
LBE40_RS02030	COG1253	flavin adenine dinucleotide binding
LBE40_RS02040	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
LBE40_RS02040	COG4651	solute:proton antiporter activity
LBE40_RS02055	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
LBE40_RS02055	COG3264	Mechanosensitive ion channel
LBE40_RS02075	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
LBE40_RS02085	COG0513	Belongs to the DEAD box helicase family
LBE40_RS02100	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LBE40_RS02115	COG0525	valine-tRNA ligase activity
LBE40_RS02125	COG1126	abc transporter atp-binding protein
LBE40_RS02130	COG0765	amino acid transport
LBE40_RS02135	COG0765	amino acid transport
LBE40_RS02150	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
LBE40_RS02155	COG0049	tRNA binding
LBE40_RS02160	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
LBE40_RS02165	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LBE40_RS02170	COG0051	transcription antitermination factor activity, RNA binding
LBE40_RS02175	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
LBE40_RS02180	COG0088	Forms part of the polypeptide exit tunnel
LBE40_RS02185	COG0089	rRNA binding
LBE40_RS02190	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
LBE40_RS02195	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
LBE40_RS02200	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
LBE40_RS02205	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
LBE40_RS02210	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
LBE40_RS02215	COG0255	Belongs to the universal ribosomal protein uL29 family
LBE40_RS02220	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
LBE40_RS02225	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
LBE40_RS02230	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
LBE40_RS02235	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
LBE40_RS02240	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
LBE40_RS02245	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
LBE40_RS02250	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
LBE40_RS02255	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
LBE40_RS02260	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
LBE40_RS02265	COG1841	ribosomal large subunit assembly
LBE40_RS02270	COG0200	Binds to the 23S rRNA
LBE40_RS02275	COG0201	protein transport
LBE40_RS02280	COG0563	adenylate kinase activity
LBE40_RS02285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
LBE40_RS02290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
LBE40_RS02295	COG0202	RNA polymerase activity
LBE40_RS02300	COG0203	ribosomal protein L17
LBE40_RS02310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
LBE40_RS02315	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
LBE40_RS02320	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
LBE40_RS02325	COG1132	(ABC) transporter
LBE40_RS02330	COG0564	pseudouridine synthase activity
LBE40_RS02360	COG0697	spore germination
LBE40_RS02365	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
LBE40_RS02380	COG0174	glutamine synthetase
LBE40_RS02385	COG0347	Belongs to the P(II) protein family
LBE40_RS02395	COG0629	single-stranded DNA binding
LBE40_RS02400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LBE40_RS02405	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
LBE40_RS02420	COG0343	queuine tRNA-ribosyltransferase activity
LBE40_RS02425	COG2814	Major facilitator Superfamily
LBE40_RS02435	COG0538	isocitrate dehydrogenase activity
LBE40_RS02455	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
LBE40_RS02470	COG0018	arginyl-trna synthetase
LBE40_RS02475	COG0232	Belongs to the dGTPase family. Type 2 subfamily
LBE40_RS02480	COG0316	Belongs to the HesB IscA family
LBE40_RS02490	COG0785	Cytochrome C biogenesis protein
LBE40_RS02495	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
LBE40_RS02500	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
LBE40_RS02505	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
LBE40_RS02515	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LBE40_RS02525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
LBE40_RS02535	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
LBE40_RS02540	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
LBE40_RS02545	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
LBE40_RS02550	COG2814	Major facilitator Superfamily
LBE40_RS02555	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
LBE40_RS02565	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LBE40_RS02570	COG0047	phosphoribosylformylglycinamidine synthase activity
LBE40_RS02575	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
LBE40_RS02580	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
LBE40_RS02590	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
LBE40_RS02600	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
LBE40_RS02620	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
LBE40_RS02625	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
LBE40_RS02630	COG0628	permease
LBE40_RS02700	COG0071	Belongs to the small heat shock protein (HSP20) family
LBE40_RS02715	COG3956	TIGRFAM MazG family protein
LBE40_RS02725	COG1063	alcohol dehydrogenase
LBE40_RS02730	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LBE40_RS02735	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LBE40_RS02740	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBE40_RS02745	COG0280	phosphate acetyltransferase
LBE40_RS02745	COG0281	malic enzyme
LBE40_RS02755	COG1923	regulation of RNA biosynthetic process
LBE40_RS02760	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
LBE40_RS02770	COG1612	heme a metabolic process
LBE40_RS02775	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
LBE40_RS02780	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
LBE40_RS02785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
LBE40_RS02790	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LBE40_RS02790	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
LBE40_RS02800	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
LBE40_RS02805	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBE40_RS02820	COG0416	fatty acid biosynthetic process
LBE40_RS02825	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
LBE40_RS02830	COG0776	regulation of translation
LBE40_RS02840	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
LBE40_RS02845	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
LBE40_RS02855	COG0302	gtp cyclohydrolase
LBE40_RS02880	COG3561	AntA/AntB antirepressor
LBE40_RS03130	COG3561	AntA/AntB antirepressor
LBE40_RS03150	COG1598	PFAM Uncharacterised protein family UPF0150
LBE40_RS03160	COG0629	single-stranded DNA binding
LBE40_RS03170	COG1598	PFAM Uncharacterised protein family UPF0150
LBE40_RS03180	COG3561	AntA/AntB antirepressor
LBE40_RS03240	COG3561	AntA/AntB antirepressor
LBE40_RS03275	COG2900	Belongs to the SlyX family
LBE40_RS03285	COG1113	amino acid transport
LBE40_RS03290	COG1122	ATPase activity
LBE40_RS03300	COG1268	BioY protein
LBE40_RS03325	COG0511	ligase activity, forming carbon-carbon bonds
LBE40_RS03350	COG1522	sequence-specific DNA binding
LBE40_RS03355	COG1573	uracil-dna glycosylase
LBE40_RS03365	COG0267	Belongs to the bacterial ribosomal protein bL33 family
LBE40_RS03370	COG0557	exoribonuclease II activity
LBE40_RS03375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
LBE40_RS03385	COG0758	DNA mediated transformation
LBE40_RS03390	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
LBE40_RS03395	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LBE40_RS03400	COG0540	Belongs to the ATCase OTCase family
LBE40_RS03410	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
LBE40_RS03415	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LBE40_RS03420	COG0154	amidase activity
LBE40_RS03430	COG0411	ABC transporter
LBE40_RS03450	COG1278	Cold shock
LBE40_RS03460	COG0596	Alpha beta hydrolase
LBE40_RS03470	COG2003	Belongs to the UPF0758 family
LBE40_RS03475	COG0024	Methionine aminopeptidase
LBE40_RS03480	COG1489	DNA binding
LBE40_RS03490	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
LBE40_RS03495	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
LBE40_RS03500	COG0037	tRNA processing
LBE40_RS03505	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBE40_RS03510	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
LBE40_RS03525	COG1686	Belongs to the peptidase S11 family
LBE40_RS03530	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
LBE40_RS03540	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LBE40_RS03545	COG0084	hydrolase, TatD family'
LBE40_RS03550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
LBE40_RS03550	COG0321	lipoyl(octanoyl) transferase activity
LBE40_RS03565	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
LBE40_RS03570	COG1183	phosphatidylcholine synthase activity
LBE40_RS03575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LBE40_RS03605	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LBE40_RS03615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
LBE40_RS03620	COG0719	Fe-S assembly protein
LBE40_RS03625	COG0396	ATPase activity
LBE40_RS03630	COG0719	Fe-S assembly protein
LBE40_RS03640	COG2945	thiolester hydrolase activity
LBE40_RS03645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
LBE40_RS03650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
LBE40_RS03660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
LBE40_RS03665	COG0860	N-Acetylmuramoyl-L-alanine amidase
LBE40_RS03670	COG1530	ribonuclease E activity
LBE40_RS03680	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
LBE40_RS03685	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
LBE40_RS03690	COG1136	(ABC) transporter
LBE40_RS03700	COG0442	prolyl-tRNA aminoacylation
LBE40_RS03715	COG1007	ATP synthesis coupled electron transport
LBE40_RS03730	COG0713	ATP synthesis coupled electron transport
LBE40_RS03740	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBE40_RS03745	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
LBE40_RS03755	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
LBE40_RS03760	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
LBE40_RS03765	COG0649	NAD binding
LBE40_RS03770	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBE40_RS03775	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
LBE40_RS03810	COG2986	histidine ammonia-lyase
LBE40_RS03825	COG0513	Belongs to the DEAD box helicase family
LBE40_RS03830	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
LBE40_RS03830	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LBE40_RS03840	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
LBE40_RS03855	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
LBE40_RS03860	COG2333	competence protein COMEC
LBE40_RS03860	COG0658	competence protein
LBE40_RS03865	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
LBE40_RS03870	COG0372	Belongs to the citrate synthase family
LBE40_RS03875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LBE40_RS03880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
LBE40_RS03885	COG4215	(ABC) transporter
LBE40_RS03895	COG1126	abc transporter atp-binding protein
LBE40_RS03900	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LBE40_RS03910	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LBE40_RS03915	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LBE40_RS03920	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
LBE40_RS03930	COG0750	zinc metalloprotease
LBE40_RS03940	COG0233	cytoplasmic translational termination
LBE40_RS03945	COG0528	UMP kinase activity
LBE40_RS03950	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
LBE40_RS03955	COG0052	Belongs to the universal ribosomal protein uS2 family
LBE40_RS03980	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
LBE40_RS03985	COG1686	Belongs to the peptidase S11 family
LBE40_RS03995	COG1760	l-serine dehydratase
LBE40_RS04005	COG0789	Transcriptional regulator
LBE40_RS04010	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
LBE40_RS04015	COG0085	RNA polymerase activity
LBE40_RS04020	COG0222	ribosome binding
LBE40_RS04025	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
LBE40_RS04030	COG0081	regulation of translation
LBE40_RS04035	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
LBE40_RS04045	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
LBE40_RS04055	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
LBE40_RS04070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
LBE40_RS04080	COG4765	Protein conserved in bacteria
LBE40_RS04090	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
LBE40_RS04095	COG0544	peptidyl-prolyl cis-trans isomerase activity
LBE40_RS04105	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
LBE40_RS04120	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
LBE40_RS04125	COG0740	serine-type endopeptidase activity
LBE40_RS04135	COG0569	domain protein
LBE40_RS04140	COG2204	response regulator
LBE40_RS04145	COG5000	phosphorelay sensor kinase activity
LBE40_RS04150	COG1959	2 iron, 2 sulfur cluster binding
LBE40_RS04155	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
LBE40_RS04155	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
LBE40_RS04160	COG1058	Belongs to the CinA family
LBE40_RS04160	COG1546	Belongs to the CinA family
LBE40_RS04165	COG2867	negative regulation of translational initiation
LBE40_RS04170	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
LBE40_RS04175	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
LBE40_RS04180	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBE40_RS04185	COG0022	dehydrogenase e1 component
LBE40_RS04185	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBE40_RS04190	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
LBE40_RS04215	COG0148	phosphopyruvate hydratase activity
LBE40_RS04220	COG2877	3-deoxy-8-phosphooctulonate synthase activity
LBE40_RS04225	COG0504	CTP synthase activity
LBE40_RS04235	COG0149	triose-phosphate isomerase activity
LBE40_RS04245	COG1562	ergosterol biosynthetic process
LBE40_RS04255	COG1862	Preprotein translocase
LBE40_RS04260	COG4942	peptidase
LBE40_RS04260	COG1388	LysM domain
LBE40_RS04265	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
LBE40_RS04270	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
LBE40_RS04275	COG0805	protein transport
LBE40_RS04280	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LBE40_RS04285	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
LBE40_RS04290	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
LBE40_RS04295	COG0322	excinuclease ABC activity
LBE40_RS04300	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
LBE40_RS04305	COG0105	UTP biosynthetic process
LBE40_RS04325	COG0477	Major facilitator Superfamily
LBE40_RS04355	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
LBE40_RS04365	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
LBE40_RS04370	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
LBE40_RS04375	COG0194	GDP metabolic process
LBE40_RS04380	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
LBE40_RS04385	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
LBE40_RS04390	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
LBE40_RS04400	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
LBE40_RS04405	COG0671	phosphoesterase, PA-phosphatase related
LBE40_RS04410	COG0360	Binds together with S18 to 16S ribosomal RNA
LBE40_RS04415	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
LBE40_RS04425	COG0359	binds to the 23S rRNA
LBE40_RS04430	COG0305	Participates in initiation and elongation during chromosome replication
LBE40_RS04455	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
LBE40_RS04460	COG1028	Short-chain dehydrogenase reductase Sdr
LBE40_RS04465	COG1183	phosphatidylcholine synthase activity
LBE40_RS04470	COG0688	phosphatidylethanolamine metabolic process
LBE40_RS04475	COG5265	(ABC) transporter
LBE40_RS04485	COG0215	cysteine-tRNA ligase activity
LBE40_RS04495	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
LBE40_RS04500	COG0354	folic acid binding
LBE40_RS04505	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
LBE40_RS04510	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
LBE40_RS04515	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
LBE40_RS04520	COG1381	Involved in DNA repair and RecF pathway recombination
LBE40_RS04530	COG0571	ribonuclease III activity
LBE40_RS04535	COG0681	Belongs to the peptidase S26 family
LBE40_RS04540	COG0736	holo-[acyl-carrier-protein] synthase activity
LBE40_RS04550	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
LBE40_RS04560	COG1758	RNA polymerase activity
LBE40_RS04565	COG1573	uracil-dna glycosylase
LBE40_RS04570	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
LBE40_RS04575	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
LBE40_RS04590	COG4771	TonB-dependent receptor
LBE40_RS04595	COG3720	iron ion transport
LBE40_RS04600	COG4558	Periplasmic binding protein
LBE40_RS04605	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
LBE40_RS04610	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
LBE40_RS04620	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
LBE40_RS04635	COG2022	thiamine diphosphate biosynthetic process
LBE40_RS04725	COG2831	hemolysin activation secretion protein
LBE40_RS04735	COG0305	Participates in initiation and elongation during chromosome replication
LBE40_RS04825	COG2831	hemolysin activation secretion protein
LBE40_RS04890	COG3041	Addiction module toxin RelE StbE family
LBE40_RS04895	COG3077	Addiction module antitoxin, RelB DinJ family
LBE40_RS04965	COG0444	Belongs to the ABC transporter superfamily
LBE40_RS04970	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
LBE40_RS04975	COG0601	transmembrane transport
LBE40_RS04980	COG0747	negative chemotaxis
LBE40_RS04985	COG0747	negative chemotaxis
LBE40_RS04995	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
LBE40_RS05000	COG0321	lipoyl(octanoyl) transferase activity
LBE40_RS05005	COG0187	DNA topoisomerase II activity
LBE40_RS05015	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
LBE40_RS05020	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
LBE40_RS05025	COG0784	Response regulator, receiver
LBE40_RS05135	COG2831	hemolysin activation secretion protein
LBE40_RS05165	COG0351	phosphomethylpyrimidine kinase
LBE40_RS05175	COG0308	aminopeptidase N
LBE40_RS05180	COG2202	Pas domain
LBE40_RS05180	COG2205	protein histidine kinase activity
LBE40_RS05190	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LBE40_RS05195	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
LBE40_RS05200	COG0642	Histidine kinase
LBE40_RS05205	COG0745	RESPONSE REGULATOR receiver
LBE40_RS05210	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
LBE40_RS05215	COG3088	subunit of a heme lyase
LBE40_RS05220	COG1138	Cytochrome C-type biogenesis protein
LBE40_RS05225	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
LBE40_RS05300	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
LBE40_RS05315	COG2166	iron-sulfur cluster assembly
LBE40_RS05330	COG0574	Belongs to the PEP-utilizing enzyme family
LBE40_RS05330	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LBE40_RS05335	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
LBE40_RS05335	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LBE40_RS05345	COG1194	a g-specific adenine glycosylase
LBE40_RS05350	COG2189	Belongs to the N(4) N(6)-methyltransferase family
LBE40_RS05355	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
LBE40_RS05380	COG0612	Peptidase, M16
LBE40_RS05385	COG1716	ATPase activity
LBE40_RS05385	COG5001	Diguanylate cyclase
LBE40_RS05390	COG1678	Uncharacterized ACR, COG1678
LBE40_RS05400	COG0328	RNA-DNA hybrid ribonuclease activity
LBE40_RS05405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
LBE40_RS05410	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
LBE40_RS05415	COG0109	protoheme IX farnesyltransferase activity
LBE40_RS05425	COG0312	modulator of DNA gyrase
LBE40_RS05440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
LBE40_RS05445	COG1722	exodeoxyribonuclease VII activity
LBE40_RS05450	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LBE40_RS05450	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
LBE40_RS05455	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
LBE40_RS05460	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LBE40_RS05465	COG0484	heat shock protein binding
LBE40_RS05470	COG0259	pyridoxamine-phosphate oxidase activity
LBE40_RS05475	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
LBE40_RS05490	COG0277	FAD linked oxidase domain protein
LBE40_RS05495	COG0009	L-threonylcarbamoyladenylate synthase
LBE40_RS05500	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
LBE40_RS05505	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
LBE40_RS05520	COG2813	Specifically methylates the guanine in position
LBE40_RS05525	COG0142	geranyltranstransferase activity
LBE40_RS05540	COG0751	glycine-tRNA ligase activity
LBE40_RS05545	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LBE40_RS05550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
LBE40_RS05555	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LBE40_RS05560	COG0356	it plays a direct role in the translocation of protons across the membrane
LBE40_RS05570	COG1160	GTP binding
LBE40_RS05580	COG0471	metal ion transport
LBE40_RS05580	COG3273	potassium ion transport
LBE40_RS05590	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
LBE40_RS05595	COG0527	aspartate kinase activity
LBE40_RS05615	COG1238	metal cluster binding
LBE40_RS05635	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
LBE40_RS05640	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
LBE40_RS05645	COG1040	competence protein
LBE40_RS05655	COG1823	symporter activity
LBE40_RS05685	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
LBE40_RS05690	COG0129	dihydroxy-acid dehydratase activity
LBE40_RS05695	COG0363	glucosamine-6-phosphate deaminase activity
LBE40_RS05700	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
LBE40_RS05705	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
LBE40_RS05725	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LBE40_RS05770	COG0167	dihydroorotate dehydrogenase activity
LBE40_RS05775	COG1970	mechanosensitive ion channel activity
LBE40_RS05795	COG0564	pseudouridine synthase activity
LBE40_RS05800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LBE40_RS05810	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
LBE40_RS05850	COG3561	AntA/AntB antirepressor
LBE40_RS06000	COG0312	modulator of DNA gyrase
LBE40_RS06005	COG0483	inositol monophosphate 1-phosphatase activity
LBE40_RS06015	COG1519	Transferase
LBE40_RS06020	COG1663	tetraacyldisaccharide 4'-kinase activity
LBE40_RS06030	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
LBE40_RS06035	COG0717	Belongs to the dCTP deaminase family
LBE40_RS06040	COG1304	FMN binding
LBE40_RS06045	COG3958	Transketolase
LBE40_RS06050	COG3959	Transketolase, thiamine diphosphate binding domain
LBE40_RS06055	COG0742	ribosomal rna small subunit methyltransferase
LBE40_RS06060	COG1187	pseudouridine synthase activity
LBE40_RS06065	COG0590	tRNA wobble adenosine to inosine editing
LBE40_RS06075	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
LBE40_RS06080	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LBE40_RS06085	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LBE40_RS06090	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
LBE40_RS06110	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
LBE40_RS06125	COG0704	Plays a role in the regulation of phosphate uptake
LBE40_RS06130	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
LBE40_RS06140	COG0573	inorganic phosphate transmembrane transporter activity
LBE40_RS06150	COG0189	ligase activity
LBE40_RS06160	COG3474	cytochrome
LBE40_RS06165	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
LBE40_RS06170	COG1605	Chorismate mutase
LBE40_RS06170	COG0077	Prephenate dehydratase
LBE40_RS06195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
LBE40_RS06200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
LBE40_RS06205	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
LBE40_RS06210	COG2855	membrane
LBE40_RS06215	COG1214	PFAM Peptidase M22, glycoprotease
LBE40_RS06225	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBE40_RS06230	COG1702	phosphate starvation-inducible protein PhoH
LBE40_RS06235	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
LBE40_RS06250	COG1396	sequence-specific DNA binding
LBE40_RS06255	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
LBE40_RS06260	COG0220	tRNA (guanine-N7-)-methyltransferase activity
LBE40_RS06265	COG0779	Required for maturation of 30S ribosomal subunits
LBE40_RS06270	COG0195	Participates in both transcription termination and antitermination
LBE40_RS06270	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
LBE40_RS06280	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
LBE40_RS06285	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
LBE40_RS06290	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
LBE40_RS06300	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
LBE40_RS06305	COG1185	polyribonucleotide nucleotidyltransferase activity
LBE40_RS06310	COG2813	Specifically methylates the guanine in position
LBE40_RS06315	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
LBE40_RS06320	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
LBE40_RS06325	COG0252	asparaginase activity
LBE40_RS06330	COG1072	(Pantothenic acid kinase))
LBE40_RS06335	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
LBE40_RS06340	COG0791	NLP P60 protein
LBE40_RS06345	COG0494	nUDIX hydrolase
LBE40_RS06350	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
LBE40_RS06355	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
LBE40_RS06360	COG0653	protein targeting
LBE40_RS06370	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
LBE40_RS06375	COG2890	protein-(glutamine-N5) methyltransferase activity
LBE40_RS06385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
LBE40_RS06390	COG1780	Probably involved in ribonucleotide reductase function
LBE40_RS06400	COG1121	(ABC) transporter
LBE40_RS06405	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LBE40_RS06410	COG0803	Belongs to the bacterial solute-binding protein 9 family
LBE40_RS06425	COG0395	ABC-type sugar transport system, permease component
LBE40_RS06430	COG3842	ATPase activity
LBE40_RS06435	COG0584	glycerophosphoryl diester phosphodiesterase
LBE40_RS06440	COG0518	GMP synthase (glutamine-hydrolyzing) activity
LBE40_RS06440	COG0519	Catalyzes the synthesis of GMP from XMP
LBE40_RS06445	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBE40_RS06445	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LBE40_RS06460	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
LBE40_RS06475	COG0517	IMP dehydrogenase activity
LBE40_RS06475	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
LBE40_RS06480	COG1210	Utp--glucose-1-phosphate uridylyltransferase
LBE40_RS06485	COG2951	lytic endotransglycosylase activity
LBE40_RS06495	COG0339	signal peptide processing
LBE40_RS06500	COG2239	Acts as a magnesium transporter
LBE40_RS06505	COG1217	gtp-binding protein TYPA
LBE40_RS06510	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
LBE40_RS06515	COG1872	DUF167
LBE40_RS06525	COG5342	invasion associated locus B
LBE40_RS06530	COG0494	nUDIX hydrolase
LBE40_RS06535	COG0793	Belongs to the peptidase S41A family
LBE40_RS06545	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
LBE40_RS06550	COG0799	negative regulation of ribosome biogenesis
LBE40_RS06555	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
LBE40_RS06560	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
LBE40_RS06565	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
LBE40_RS06570	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
LBE40_RS06575	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
LBE40_RS06580	COG0248	Ppx GppA phosphatase
LBE40_RS06685	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
LBE40_RS06685	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
LBE40_RS06690	COG0211	Belongs to the bacterial ribosomal protein bL27 family
LBE40_RS06695	COG0261	This protein binds to 23S rRNA in the presence of protein L20
LBE40_RS06705	COG0166	Belongs to the GPI family
LBE40_RS06710	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
LBE40_RS06725	COG2759	Belongs to the formate--tetrahydrofolate ligase family
LBE40_RS06730	COG0828	Belongs to the bacterial ribosomal protein bS21 family
LBE40_RS06745	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
LBE40_RS06755	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
LBE40_RS06760	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
LBE40_RS06765	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
LBE40_RS06770	COG1845	cytochrome c oxidase, subunit III
LBE40_RS06775	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
LBE40_RS06780	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
LBE40_RS06785	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
LBE40_RS06800	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
LBE40_RS06805	COG0268	Binds directly to 16S ribosomal RNA
LBE40_RS06810	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
LBE40_RS06815	COG4133	protoheme IX ABC transporter activity
LBE40_RS06820	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LBE40_RS06825	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
LBE40_RS06835	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
LBE40_RS06845	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
LBE40_RS06870	COG3030	protein affecting phage T7 exclusion by the F plasmid
LBE40_RS06875	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
LBE40_RS06880	COG0281	malic enzyme
LBE40_RS06880	COG0280	phosphate acetyltransferase
LBE40_RS06885	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
LBE40_RS06890	COG0129	dihydroxy-acid dehydratase activity
LBE40_RS06905	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
LBE40_RS06910	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
LBE40_RS06915	COG0539	negative regulation of cytoplasmic translation
LBE40_RS06920	COG3459	Glycosyltransferase 36 associated
LBE40_RS06925	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
LBE40_RS06930	COG2832	Protein of unknown function (DUF454)
LBE40_RS06935	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LBE40_RS06940	COG1108	ABC-type Mn2 Zn2 transport systems permease components
LBE40_RS06945	COG1121	(ABC) transporter
LBE40_RS06955	COG0072	phenylalanine-tRNA ligase activity
LBE40_RS06955	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
LBE40_RS06960	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
LBE40_RS06965	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
LBE40_RS06970	COG0291	Belongs to the bacterial ribosomal protein bL35 family
LBE40_RS07000	COG0242	peptide deformylase activity
LBE40_RS07005	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
LBE40_RS07010	COG0101	tRNA pseudouridine synthase activity
LBE40_RS07020	COG2171	N-acyltransferase activity
LBE40_RS07025	COG0481	GTPase activity
LBE40_RS07035	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
LBE40_RS07040	COG0484	heat shock protein binding
LBE40_RS07045	COG0443	Heat shock 70 kDa protein
LBE40_RS07055	COG1652	LysM domain
LBE40_RS07060	COG0745	RESPONSE REGULATOR receiver
LBE40_RS07065	COG0642	Histidine kinase
LBE40_RS07075	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
LBE40_RS07090	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
LBE40_RS07095	COG1420	regulation of RNA biosynthetic process
LBE40_RS07100	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
LBE40_RS07105	COG0635	Involved in the biosynthesis of porphyrin-containing compound
LBE40_RS07110	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
LBE40_RS07125	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
LBE40_RS07130	COG1132	(ABC) transporter
LBE40_RS07145	COG0606	chelatase, subunit chli
LBE40_RS07160	COG2226	methyltransferase
LBE40_RS07165	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
LBE40_RS07170	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
LBE40_RS07180	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
LBE40_RS07185	COG0285	dihydrofolate synthase activity
LBE40_RS07195	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
LBE40_RS07200	COG2205	protein histidine kinase activity
LBE40_RS07205	COG0802	atpase or kinase
LBE40_RS07210	COG2887	Belongs to the helicase family. UvrD subfamily
LBE40_RS07225	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
LBE40_RS07235	COG0137	argininosuccinate synthase activity
LBE40_RS07245	COG0820	rRNA (adenine-C2-)-methyltransferase activity
LBE40_RS07255	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
LBE40_RS07260	COG1137	ATPase activity
LBE40_RS07275	COG0776	regulation of translation
LBE40_RS07285	COG0116	Belongs to the methyltransferase superfamily
LBE40_RS07285	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
LBE40_RS07295	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
LBE40_RS07300	COG0670	Belongs to the BI1 family
LBE40_RS07310	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LBE40_RS07310	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
LBE40_RS07320	COG0237	dephospho-CoA kinase activity
LBE40_RS07325	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
LBE40_RS07330	COG0424	maF-like protein
LBE40_RS07335	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
LBE40_RS07340	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
LBE40_RS07345	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
LBE40_RS07350	COG0445	tRNA wobble uridine modification
LBE40_RS07355	COG0357	Ribosomal RNA small subunit methyltransferase G
LBE40_RS07380	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
LBE40_RS07385	COG2917	probably involved in intracellular septation
LBE40_RS07390	COG0552	protein localization to endoplasmic reticulum
LBE40_RS07395	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
LBE40_RS07400	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
LBE40_RS07410	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
LBE40_RS07415	COG0039	L-malate dehydrogenase activity
LBE40_RS07420	COG0045	succinate-CoA ligase (ADP-forming) activity
LBE40_RS07425	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
LBE40_RS07430	COG0567	Dehydrogenase, E1 component
LBE40_RS07435	COG0508	dehydrogenase complex catalyzes the overall conversion of
LBE40_RS07450	COG0019	diaminopimelate decarboxylase activity
LBE40_RS07460	COG2111	Na H antiporter
LBE40_RS07460	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
LBE40_RS07465	COG1006	Multisubunit Na H antiporter MnhC subunit
LBE40_RS07470	COG0651	ATP synthesis coupled electron transport
LBE40_RS07475	COG1863	multisubunit Na H antiporter MnhE subunit
LBE40_RS07480	COG2212	antiporter activity
LBE40_RS07485	COG1320	monovalent cation:proton antiporter activity
LBE40_RS07505	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
LBE40_RS07510	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
LBE40_RS07525	COG0825	malonyl-CoA metabolic process
LBE40_RS07530	COG3034	peptidoglycan biosynthetic process
LBE40_RS07535	COG0523	cobalamin synthesis protein
LBE40_RS07540	COG1686	Belongs to the peptidase S11 family
LBE40_RS07555	COG0431	NADPH-dependent FMN reductase
LBE40_RS07575	COG3840	Part of the ABC transporter complex ThiBPQ involved in thiamine import. Responsible for energy coupling to the transport system
LBE40_RS07585	COG0287	Prephenate dehydrogenase
LBE40_RS07595	COG1671	Belongs to the UPF0178 family
LBE40_RS07605	COG0165	Argininosuccinate lyase
LBE40_RS07640	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
LBE40_RS07665	COG2902	Dehydrogenase
LBE40_RS07670	COG0288	reversible hydration of carbon dioxide
LBE40_RS07675	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
LBE40_RS07685	COG0228	four-way junction DNA binding
LBE40_RS07690	COG5508	conserved small protein
LBE40_RS07695	COG0501	Belongs to the peptidase M48B family
LBE40_RS07700	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
LBE40_RS07700	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
LBE40_RS07710	COG0138	bifunctional purine biosynthesis protein purh
LBE40_RS07725	COG0227	Belongs to the bacterial ribosomal protein bL28 family
LBE40_RS07765	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
LBE40_RS07770	COG0336	Belongs to the RNA methyltransferase TrmD family
LBE40_RS07775	COG0335	large ribosomal subunit rRNA binding
LBE40_RS07805	COG2948	multi-organism process
LBE40_RS07810	COG3504	Conjugal transfer protein
LBE40_RS07965	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
LBE40_RS07970	COG1674	ftsk spoiiie
LBE40_RS07985	COG1538	Outer membrane efflux protein
LBE40_RS07990	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
LBE40_RS07995	COG1136	(ABC) transporter
LBE40_RS07995	COG0577	efflux transmembrane transporter activity
LBE40_RS08010	COG2884	Cell division ATP-binding protein ftsE
LBE40_RS08015	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
LBE40_RS08050	COG0495	leucyl-tRNA aminoacylation
LBE40_RS08060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
LBE40_RS08070	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
LBE40_RS08075	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
LBE40_RS08080	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
LBE40_RS08085	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
LBE40_RS08090	COG0355	proton-transporting ATP synthase activity, rotational mechanism
LBE40_RS08100	COG1566	PFAM secretion protein HlyD family protein
LBE40_RS08110	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
LBE40_RS08145	COG0142	geranyltranstransferase activity
LBE40_RS08150	COG0333	Belongs to the bacterial ribosomal protein bL32 family
LBE40_RS08160	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
LBE40_RS08170	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
LBE40_RS08190	COG0488	(ABC) transporter
LBE40_RS08195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
LBE40_RS08200	COG3750	Belongs to the UPF0335 family
LBE40_RS08210	COG0469	pyruvate kinase activity
LBE40_RS08240	COG0126	phosphoglycerate kinase activity
LBE40_RS08245	COG3588	fructose-bisphosphate aldolase
LBE40_RS08250	COG0254	rRNA binding
LBE40_RS08255	COG1132	(ABC) transporter
LBE40_RS08265	COG0483	inositol monophosphate 1-phosphatase activity
LBE40_RS08270	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
LBE40_RS08285	COG1396	sequence-specific DNA binding
LBE40_RS08310	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
LBE40_RS08320	COG0632	four-way junction helicase activity
LBE40_RS08325	COG2255	four-way junction helicase activity
LBE40_RS08330	COG0824	Thioesterase
LBE40_RS08350	COG0823	Involved in the tonB-independent uptake of proteins