locus-tag	class	description
BTR_RS00005	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BTR_RS00095	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BTR_RS00100	COG0424	maF-like protein
BTR_RS00105	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BTR_RS00110	COG0237	dephospho-CoA kinase activity
BTR_RS00115	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BTR_RS00120	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTR_RS00120	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTR_RS00130	COG0670	Belongs to the BI1 family
BTR_RS00140	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BTR_RS00150	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BTR_RS00150	COG0116	Belongs to the methyltransferase superfamily
BTR_RS00160	COG0776	regulation of translation
BTR_RS00175	COG1137	ATPase activity
BTR_RS00180	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR_RS00190	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BTR_RS00200	COG0137	argininosuccinate synthase activity
BTR_RS00210	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BTR_RS00215	COG2887	Belongs to the helicase family. UvrD subfamily
BTR_RS00230	COG0802	atpase or kinase
BTR_RS00235	COG2205	protein histidine kinase activity
BTR_RS00240	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BTR_RS00250	COG0285	dihydrofolate synthase activity
BTR_RS00255	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BTR_RS00270	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BTR_RS00275	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BTR_RS00280	COG2226	methyltransferase
BTR_RS00295	COG0606	chelatase, subunit chli
BTR_RS00310	COG1132	(ABC) transporter
BTR_RS00315	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BTR_RS00330	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BTR_RS00335	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BTR_RS00340	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BTR_RS00350	COG1420	regulation of RNA biosynthetic process
BTR_RS00355	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BTR_RS00370	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR_RS00370	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BTR_RS00375	COG1136	(ABC) transporter
BTR_RS00380	COG2205	protein histidine kinase activity
BTR_RS00385	COG0745	RESPONSE REGULATOR receiver
BTR_RS00390	COG1652	LysM domain
BTR_RS00400	COG0443	Heat shock 70 kDa protein
BTR_RS00405	COG0484	heat shock protein binding
BTR_RS00410	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BTR_RS00425	COG0481	GTPase activity
BTR_RS00430	COG2171	N-acyltransferase activity
BTR_RS00440	COG0101	tRNA pseudouridine synthase activity
BTR_RS00445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BTR_RS00450	COG0242	peptide deformylase activity
BTR_RS00475	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BTR_RS00480	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BTR_RS00485	COG0539	negative regulation of cytoplasmic translation
BTR_RS00490	COG3459	Glycosyltransferase 36 associated
BTR_RS00495	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
BTR_RS00500	COG2832	Protein of unknown function (DUF454)
BTR_RS00505	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTR_RS00510	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BTR_RS00515	COG1121	(ABC) transporter
BTR_RS00535	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BTR_RS00535	COG0072	phenylalanine-tRNA ligase activity
BTR_RS00540	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BTR_RS00545	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BTR_RS00550	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BTR_RS00570	COG0129	dihydroxy-acid dehydratase activity
BTR_RS00580	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BTR_RS00585	COG0281	malic enzyme
BTR_RS00585	COG0280	phosphate acetyltransferase
BTR_RS00590	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BTR_RS00595	COG3030	protein affecting phage T7 exclusion by the F plasmid
BTR_RS00615	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BTR_RS00625	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BTR_RS00635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTR_RS00645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTR_RS00650	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BTR_RS00655	COG4133	protoheme IX ABC transporter activity
BTR_RS00660	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BTR_RS00665	COG0268	Binds directly to 16S ribosomal RNA
BTR_RS00670	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BTR_RS00685	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BTR_RS00695	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BTR_RS00700	COG1845	cytochrome c oxidase, subunit III
BTR_RS00705	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BTR_RS00710	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BTR_RS00725	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BTR_RS00735	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTR_RS00750	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BTR_RS00755	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BTR_RS00770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BTR_RS00775	COG0166	Belongs to the GPI family
BTR_RS00785	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BTR_RS00790	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BTR_RS00800	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BTR_RS00800	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTR_RS00820	COG0582	viral genome integration into host DNA
BTR_RS00850	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTR_RS00875	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BTR_RS00880	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BTR_RS00885	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BTR_RS00890	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BTR_RS00900	COG0799	negative regulation of ribosome biogenesis
BTR_RS00905	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BTR_RS00915	COG0793	Belongs to the peptidase S41A family
BTR_RS00920	COG0494	nUDIX hydrolase
BTR_RS00925	COG5342	invasion associated locus B
BTR_RS00935	COG1872	DUF167
BTR_RS00940	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BTR_RS00945	COG1217	gtp-binding protein TYPA
BTR_RS00950	COG2239	Acts as a magnesium transporter
BTR_RS00955	COG0339	signal peptide processing
BTR_RS00965	COG2951	lytic endotransglycosylase activity
BTR_RS00970	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BTR_RS00975	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BTR_RS00975	COG0517	IMP dehydrogenase activity
BTR_RS00990	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BTR_RS01000	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTR_RS01000	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTR_RS01005	COG0519	Catalyzes the synthesis of GMP from XMP
BTR_RS01005	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BTR_RS01010	COG0584	glycerophosphoryl diester phosphodiesterase
BTR_RS01025	COG0395	ABC-type sugar transport system, permease component
BTR_RS01030	COG3842	ATPase activity
BTR_RS01040	COG0803	Belongs to the bacterial solute-binding protein 9 family
BTR_RS01060	COG1780	Probably involved in ribonucleotide reductase function
BTR_RS01065	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BTR_RS01075	COG2890	protein-(glutamine-N5) methyltransferase activity
BTR_RS01080	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BTR_RS01090	COG0653	protein targeting
BTR_RS01095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BTR_RS01100	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BTR_RS01105	COG0494	nUDIX hydrolase
BTR_RS01120	COG0791	NLP P60 protein
BTR_RS01125	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BTR_RS01130	COG1072	(Pantothenic acid kinase))
BTR_RS01135	COG0252	asparaginase activity
BTR_RS01140	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BTR_RS01145	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BTR_RS01150	COG2813	Specifically methylates the guanine in position
BTR_RS01155	COG1185	polyribonucleotide nucleotidyltransferase activity
BTR_RS01160	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BTR_RS01170	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BTR_RS01175	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BTR_RS01180	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BTR_RS01190	COG0195	Participates in both transcription termination and antitermination
BTR_RS01190	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTR_RS01195	COG0779	Required for maturation of 30S ribosomal subunits
BTR_RS01200	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BTR_RS01205	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BTR_RS01210	COG1396	sequence-specific DNA binding
BTR_RS01225	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BTR_RS01230	COG1702	phosphate starvation-inducible protein PhoH
BTR_RS01235	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTR_RS01240	COG0456	acetyltransferase
BTR_RS01245	COG1214	PFAM Peptidase M22, glycoprotease
BTR_RS01250	COG2855	membrane
BTR_RS01255	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BTR_RS01260	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BTR_RS01275	COG0077	Prephenate dehydratase
BTR_RS01275	COG1605	Chorismate mutase
BTR_RS01280	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BTR_RS01285	COG3474	cytochrome
BTR_RS01300	COG0189	ligase activity
BTR_RS01310	COG0573	inorganic phosphate transmembrane transporter activity
BTR_RS01320	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BTR_RS01325	COG0704	Plays a role in the regulation of phosphate uptake
BTR_RS01340	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BTR_RS01350	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BTR_RS01360	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTR_RS01365	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTR_RS01370	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTR_RS01375	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BTR_RS01385	COG0590	tRNA wobble adenosine to inosine editing
BTR_RS01395	COG0742	ribosomal rna small subunit methyltransferase
BTR_RS01405	COG0312	modulator of DNA gyrase
BTR_RS01410	COG0483	inositol monophosphate 1-phosphatase activity
BTR_RS01420	COG1519	Transferase
BTR_RS01425	COG1663	tetraacyldisaccharide 4'-kinase activity
BTR_RS01435	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BTR_RS01440	COG0717	Belongs to the dCTP deaminase family
BTR_RS01445	COG1304	FMN binding
BTR_RS01475	COG0582	viral genome integration into host DNA
BTR_RS01480	COG3561	AntA/AntB antirepressor
BTR_RS01485	COG3077	Addiction module antitoxin, RelB DinJ family
BTR_RS01490	COG3041	Addiction module toxin RelE StbE family
BTR_RS01510	COG3657	addiction module killer protein
BTR_RS01555	COG3561	AntA/AntB antirepressor
BTR_RS01720	COG1598	PFAM Uncharacterised protein family UPF0150
BTR_RS01730	COG0629	single-stranded DNA binding
BTR_RS01790	COG3561	AntA/AntB antirepressor
BTR_RS01800	COG3561	AntA/AntB antirepressor
BTR_RS01825	COG2900	Belongs to the SlyX family
BTR_RS01835	COG1113	amino acid transport
BTR_RS01840	COG1122	ATPase activity
BTR_RS01850	COG1268	BioY protein
BTR_RS01855	COG1268	BioY protein
BTR_RS01865	COG3041	Addiction module toxin RelE StbE family
BTR_RS01870	COG3077	Addiction module antitoxin, RelB DinJ family
BTR_RS01885	COG2831	hemolysin activation secretion protein
BTR_RS01890	COG3210	domain, Protein
BTR_RS01890	COG3210	domain, Protein
BTR_RS01965	COG3210	domain, Protein
BTR_RS01965	COG3210	domain, Protein
BTR_RS01985	COG3210	domain, Protein
BTR_RS01995	COG3210	domain, Protein
BTR_RS02005	COG3210	domain, Protein
BTR_RS02030	COG0582	viral genome integration into host DNA
BTR_RS02130	COG0629	single-stranded DNA binding
BTR_RS02170	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTR_RS02185	COG0556	nucleotide-excision repair
BTR_RS02280	COG0582	viral genome integration into host DNA
BTR_RS02300	COG3077	Addiction module antitoxin, RelB DinJ family
BTR_RS02305	COG3041	Addiction module toxin RelE StbE family
BTR_RS02385	COG3561	AntA/AntB antirepressor
BTR_RS02560	COG1598	PFAM Uncharacterised protein family UPF0150
BTR_RS02570	COG0582	viral genome integration into host DNA
BTR_RS02610	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTR_RS02615	COG0629	single-stranded DNA binding
BTR_RS02675	COG3561	AntA/AntB antirepressor
BTR_RS02725	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BTR_RS02735	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTR_RS02740	COG0564	pseudouridine synthase activity
BTR_RS02760	COG1970	mechanosensitive ion channel activity
BTR_RS02765	COG0167	dihydroorotate dehydrogenase activity
BTR_RS02840	COG0534	Mate efflux family protein
BTR_RS02855	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BTR_RS02860	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BTR_RS02865	COG0363	glucosamine-6-phosphate deaminase activity
BTR_RS02870	COG0129	dihydroxy-acid dehydratase activity
BTR_RS02875	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BTR_RS02900	COG1823	symporter activity
BTR_RS02905	COG2226	methyltransferase
BTR_RS02910	COG1040	competence protein
BTR_RS02915	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BTR_RS02920	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BTR_RS02925	COG0527	aspartate kinase activity
BTR_RS02930	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BTR_RS02940	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BTR_RS02950	COG0471	metal ion transport
BTR_RS02950	COG3273	potassium ion transport
BTR_RS02960	COG1160	GTP binding
BTR_RS02970	COG0356	it plays a direct role in the translocation of protons across the membrane
BTR_RS02980	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BTR_RS02985	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BTR_RS03000	COG0751	glycine-tRNA ligase activity
BTR_RS03015	COG0142	geranyltranstransferase activity
BTR_RS03030	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BTR_RS03035	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BTR_RS03040	COG0009	L-threonylcarbamoyladenylate synthase
BTR_RS03045	COG0277	FAD linked oxidase domain protein
BTR_RS03060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BTR_RS03065	COG0259	pyridoxamine-phosphate oxidase activity
BTR_RS03070	COG0484	heat shock protein binding
BTR_RS03075	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BTR_RS03080	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BTR_RS03085	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTR_RS03085	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BTR_RS03090	COG1722	exodeoxyribonuclease VII activity
BTR_RS03095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BTR_RS03100	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BTR_RS03110	COG0312	modulator of DNA gyrase
BTR_RS03120	COG0109	protoheme IX farnesyltransferase activity
BTR_RS03125	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BTR_RS03130	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BTR_RS03135	COG0328	RNA-DNA hybrid ribonuclease activity
BTR_RS03145	COG1678	Uncharacterized ACR, COG1678
BTR_RS03155	COG1716	ATPase activity
BTR_RS03155	COG5001	Diguanylate cyclase
BTR_RS03165	COG0612	Peptidase, M16
BTR_RS03200	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BTR_RS03210	COG1194	a g-specific adenine glycosylase
BTR_RS03220	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BTR_RS03225	COG0574	Belongs to the PEP-utilizing enzyme family
BTR_RS03225	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BTR_RS03250	COG2166	iron-sulfur cluster assembly
BTR_RS03265	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BTR_RS03325	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTR_RS03355	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BTR_RS03360	COG1138	Cytochrome C-type biogenesis protein
BTR_RS03365	COG3088	subunit of a heme lyase
BTR_RS03370	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTR_RS03375	COG0745	RESPONSE REGULATOR receiver
BTR_RS03380	COG0642	Histidine kinase
BTR_RS03385	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BTR_RS03390	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTR_RS03425	COG0714	Associated with various cellular activities
BTR_RS03430	COG0617	tRNA 3'-terminal CCA addition
BTR_RS03435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BTR_RS03440	COG0723	plastoquinol--plastocyanin reductase activity
BTR_RS03450	COG2857	Cytochrome c1
BTR_RS03450	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BTR_RS03465	COG1376	ErfK ybiS ycfS ynhG family protein
BTR_RS03470	COG0193	aminoacyl-tRNA hydrolase activity
BTR_RS03475	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BTR_RS03490	COG1496	oxidoreductase activity
BTR_RS03500	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BTR_RS03520	COG2205	protein histidine kinase activity
BTR_RS03525	COG0745	RESPONSE REGULATOR receiver
BTR_RS03530	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTR_RS03540	COG0556	nucleotide-excision repair
BTR_RS03550	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BTR_RS03560	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BTR_RS03565	COG0492	ferredoxin-NADP+ reductase activity
BTR_RS03570	COG0583	DNA-binding transcription factor activity
BTR_RS03580	COG0436	Aminotransferase
BTR_RS03585	COG1278	Cold shock
BTR_RS03600	COG2205	protein histidine kinase activity
BTR_RS03600	COG2202	Pas domain
BTR_RS03605	COG0308	aminopeptidase N
BTR_RS03615	COG0351	phosphomethylpyrimidine kinase
BTR_RS03625	COG2022	thiamine diphosphate biosynthetic process
BTR_RS03640	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BTR_RS03655	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BTR_RS03660	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTR_RS03665	COG4558	Periplasmic binding protein
BTR_RS03670	COG3720	iron ion transport
BTR_RS03690	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BTR_RS03695	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BTR_RS03700	COG1573	uracil-dna glycosylase
BTR_RS03705	COG1758	RNA polymerase activity
BTR_RS03710	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BTR_RS03715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BTR_RS03725	COG0736	holo-[acyl-carrier-protein] synthase activity
BTR_RS03730	COG0681	Belongs to the peptidase S26 family
BTR_RS03735	COG0571	ribonuclease III activity
BTR_RS03745	COG1381	Involved in DNA repair and RecF pathway recombination
BTR_RS03750	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BTR_RS03755	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BTR_RS03760	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BTR_RS03765	COG0354	folic acid binding
BTR_RS03770	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BTR_RS03790	COG0215	cysteine-tRNA ligase activity
BTR_RS03800	COG5265	(ABC) transporter
BTR_RS03805	COG0688	phosphatidylethanolamine metabolic process
BTR_RS03810	COG1183	phosphatidylcholine synthase activity
BTR_RS03815	COG1028	Short-chain dehydrogenase reductase Sdr
BTR_RS03820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BTR_RS03835	COG0305	Participates in initiation and elongation during chromosome replication
BTR_RS03840	COG0359	binds to the 23S rRNA
BTR_RS03850	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BTR_RS03855	COG0360	Binds together with S18 to 16S ribosomal RNA
BTR_RS03860	COG0671	phosphoesterase, PA-phosphatase related
BTR_RS03865	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BTR_RS03875	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTR_RS03880	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTR_RS03885	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BTR_RS03890	COG0194	GDP metabolic process
BTR_RS03895	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BTR_RS03900	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BTR_RS03910	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BTR_RS03935	COG0477	Major facilitator Superfamily
BTR_RS03960	COG0105	UTP biosynthetic process
BTR_RS03965	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BTR_RS03970	COG0322	excinuclease ABC activity
BTR_RS03975	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BTR_RS03985	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTR_RS03990	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BTR_RS03995	COG0805	protein transport
BTR_RS04000	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BTR_RS04005	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BTR_RS04010	COG4942	peptidase
BTR_RS04015	COG1862	Preprotein translocase
BTR_RS04040	COG0149	triose-phosphate isomerase activity
BTR_RS04045	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTR_RS04050	COG0504	CTP synthase activity
BTR_RS04055	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BTR_RS04060	COG0148	phosphopyruvate hydratase activity
BTR_RS04075	COG2314	TM2 domain
BTR_RS04085	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BTR_RS04090	COG0022	dehydrogenase e1 component
BTR_RS04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTR_RS04095	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTR_RS04100	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BTR_RS04105	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BTR_RS04110	COG2867	negative regulation of translational initiation
BTR_RS04115	COG1546	Belongs to the CinA family
BTR_RS04115	COG1058	Belongs to the CinA family
BTR_RS04120	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BTR_RS04125	COG1959	2 iron, 2 sulfur cluster binding
BTR_RS04130	COG5000	phosphorelay sensor kinase activity
BTR_RS04135	COG2204	response regulator
BTR_RS04140	COG0569	domain protein
BTR_RS04150	COG0740	serine-type endopeptidase activity
BTR_RS04155	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BTR_RS04170	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BTR_RS04180	COG0544	peptidyl-prolyl cis-trans isomerase activity
BTR_RS04185	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTR_RS04195	COG4765	Protein conserved in bacteria
BTR_RS04205	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BTR_RS04220	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTR_RS04230	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BTR_RS04240	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BTR_RS04245	COG0081	regulation of translation
BTR_RS04250	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BTR_RS04255	COG0222	ribosome binding
BTR_RS04260	COG0085	RNA polymerase activity
BTR_RS04265	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BTR_RS04280	COG1760	l-serine dehydratase
BTR_RS04290	COG1686	Belongs to the peptidase S11 family
BTR_RS04295	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BTR_RS04320	COG0052	Belongs to the universal ribosomal protein uS2 family
BTR_RS04325	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BTR_RS04330	COG0528	UMP kinase activity
BTR_RS04335	COG0233	cytoplasmic translational termination
BTR_RS04345	COG0750	zinc metalloprotease
BTR_RS04350	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTR_RS04355	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTR_RS04360	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BTR_RS04365	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTR_RS04375	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BTR_RS04380	COG1126	abc transporter atp-binding protein
BTR_RS04400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BTR_RS04405	COG0372	Belongs to the citrate synthase family
BTR_RS04410	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTR_RS04415	COG0658	competence protein
BTR_RS04415	COG2333	competence protein COMEC
BTR_RS04420	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BTR_RS04435	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BTR_RS04445	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BTR_RS04445	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BTR_RS04465	COG0477	Major facilitator Superfamily
BTR_RS04560	COG0629	single-stranded DNA binding
BTR_RS04570	COG1598	PFAM Uncharacterised protein family UPF0150
BTR_RS04575	COG3561	AntA/AntB antirepressor
BTR_RS04695	COG3561	AntA/AntB antirepressor
BTR_RS04780	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTR_RS04820	COG0582	viral genome integration into host DNA
BTR_RS04855	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTR_RS04885	COG0582	viral genome integration into host DNA
BTR_RS04915	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTR_RS04930	COG3210	domain, Protein
BTR_RS04930	COG3210	domain, Protein
BTR_RS04960	COG0582	viral genome integration into host DNA
BTR_RS04970	COG0582	viral genome integration into host DNA
BTR_RS05010	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTR_RS05110	COG0697	spore germination
BTR_RS05145	COG0582	viral genome integration into host DNA
BTR_RS05170	COG3657	addiction module killer protein
BTR_RS05205	COG0741	lytic transglycosylase activity
BTR_RS05220	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BTR_RS05260	COG0582	viral genome integration into host DNA
BTR_RS05320	COG0511	ligase activity, forming carbon-carbon bonds
BTR_RS05335	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BTR_RS05345	COG1522	sequence-specific DNA binding
BTR_RS05350	COG1573	uracil-dna glycosylase
BTR_RS05360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BTR_RS05370	COG0557	exoribonuclease II activity
BTR_RS05375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BTR_RS05380	COG0758	DNA mediated transformation
BTR_RS05385	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BTR_RS05390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BTR_RS05395	COG0540	Belongs to the ATCase OTCase family
BTR_RS05405	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BTR_RS05410	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BTR_RS05415	COG0154	amidase activity
BTR_RS05425	COG0411	ABC transporter
BTR_RS05445	COG1278	Cold shock
BTR_RS05455	COG0596	Alpha beta hydrolase
BTR_RS05465	COG2003	Belongs to the UPF0758 family
BTR_RS05470	COG0024	Methionine aminopeptidase
BTR_RS05475	COG1489	DNA binding
BTR_RS05480	COG0565	Catalyzes the formation of 2'O-methylated cytidine (Cm32) or 2'O-methylated uridine (Um32) at position 32 in tRNA
BTR_RS05485	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BTR_RS05490	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BTR_RS05495	COG0037	tRNA processing
BTR_RS05500	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTR_RS05505	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BTR_RS05525	COG1686	Belongs to the peptidase S11 family
BTR_RS05530	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BTR_RS05545	COG0084	hydrolase, TatD family'
BTR_RS05550	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BTR_RS05550	COG0321	lipoyl(octanoyl) transferase activity
BTR_RS05570	COG1183	phosphatidylcholine synthase activity
BTR_RS05575	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTR_RS05605	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BTR_RS05615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BTR_RS05620	COG0719	Fe-S assembly protein
BTR_RS05625	COG0396	ATPase activity
BTR_RS05630	COG0719	Fe-S assembly protein
BTR_RS05640	COG2945	thiolester hydrolase activity
BTR_RS05645	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BTR_RS05650	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BTR_RS05660	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BTR_RS05665	COG0860	N-Acetylmuramoyl-L-alanine amidase
BTR_RS05670	COG1530	ribonuclease E activity
BTR_RS05685	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BTR_RS05690	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BTR_RS05695	COG1136	(ABC) transporter
BTR_RS05705	COG0442	prolyl-tRNA aminoacylation
BTR_RS05715	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BTR_RS05715	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BTR_RS05720	COG1007	ATP synthesis coupled electron transport
BTR_RS05735	COG0713	ATP synthesis coupled electron transport
BTR_RS05745	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTR_RS05750	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BTR_RS05760	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BTR_RS05765	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BTR_RS05770	COG0649	NAD binding
BTR_RS05775	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTR_RS05780	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BTR_RS05915	COG2369	cell adhesion
BTR_RS05920	COG4383	Mu-like prophage protein gp29
BTR_RS05925	COG4373	Mu-like prophage FluMu protein gp28
BTR_RS05960	COG3179	chitinase
BTR_RS05990	COG2842	Transposition protein
BTR_RS06010	COG1475	DNA binding
BTR_RS06140	COG2369	cell adhesion
BTR_RS06185	COG2831	hemolysin activation secretion protein
BTR_RS06215	COG0302	gtp cyclohydrolase
BTR_RS06225	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BTR_RS06230	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BTR_RS06240	COG0776	regulation of translation
BTR_RS06245	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BTR_RS06250	COG0416	fatty acid biosynthetic process
BTR_RS06265	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTR_RS06270	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BTR_RS06280	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTR_RS06280	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BTR_RS06285	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BTR_RS06290	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BTR_RS06295	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BTR_RS06300	COG1612	heme a metabolic process
BTR_RS06310	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BTR_RS06315	COG1923	regulation of RNA biosynthetic process
BTR_RS06325	COG0281	malic enzyme
BTR_RS06325	COG0280	phosphate acetyltransferase
BTR_RS06330	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BTR_RS06340	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BTR_RS06345	COG1063	alcohol dehydrogenase
BTR_RS06355	COG3956	TIGRFAM MazG family protein
BTR_RS06370	COG0071	Belongs to the small heat shock protein (HSP20) family
BTR_RS06410	COG0628	permease
BTR_RS06415	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BTR_RS06420	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BTR_RS06440	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BTR_RS06450	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BTR_RS06460	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BTR_RS06465	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTR_RS06470	COG0047	phosphoribosylformylglycinamidine synthase activity
BTR_RS06475	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BTR_RS06485	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BTR_RS06490	COG2814	Major facilitator Superfamily
BTR_RS06495	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTR_RS06500	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BTR_RS06505	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BTR_RS06510	COG0248	Ppx GppA phosphatase
BTR_RS06515	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BTR_RS06525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTR_RS06535	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BTR_RS06540	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BTR_RS06545	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BTR_RS06550	COG0785	Cytochrome C biogenesis protein
BTR_RS06560	COG0316	Belongs to the HesB IscA family
BTR_RS06565	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BTR_RS06570	COG0018	arginyl-trna synthetase
BTR_RS06585	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BTR_RS06590	COG1494	fructose-1,6-bisphosphatase
BTR_RS06610	COG0538	isocitrate dehydrogenase activity
BTR_RS06730	COG2369	cell adhesion
BTR_RS06735	COG4383	Mu-like prophage protein gp29
BTR_RS06740	COG4373	Mu-like prophage FluMu protein gp28
BTR_RS06775	COG3179	chitinase
BTR_RS06805	COG2842	Transposition protein
BTR_RS06825	COG1475	DNA binding
BTR_RS06850	COG2814	Major facilitator Superfamily
BTR_RS06855	COG0343	queuine tRNA-ribosyltransferase activity
BTR_RS06880	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BTR_RS06885	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BTR_RS06890	COG0629	single-stranded DNA binding
BTR_RS06900	COG0347	Belongs to the P(II) protein family
BTR_RS06905	COG0174	glutamine synthetase
BTR_RS06995	COG2986	histidine ammonia-lyase
BTR_RS07020	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BTR_RS07025	COG0321	lipoyl(octanoyl) transferase activity
BTR_RS07030	COG0187	DNA topoisomerase II activity
BTR_RS07040	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BTR_RS07045	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BTR_RS07050	COG0784	Response regulator, receiver
BTR_RS07080	COG4555	ABC transporter
BTR_RS07095	COG1132	(ABC) transporter
BTR_RS07100	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BTR_RS07105	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BTR_RS07115	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BTR_RS07120	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTR_RS07125	COG0203	ribosomal protein L17
BTR_RS07130	COG0202	RNA polymerase activity
BTR_RS07135	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BTR_RS07140	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BTR_RS07145	COG0563	adenylate kinase activity
BTR_RS07150	COG0201	protein transport
BTR_RS07155	COG0200	Binds to the 23S rRNA
BTR_RS07160	COG1841	ribosomal large subunit assembly
BTR_RS07165	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BTR_RS07170	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BTR_RS07175	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BTR_RS07180	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BTR_RS07185	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BTR_RS07190	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BTR_RS07195	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BTR_RS07200	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BTR_RS07205	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BTR_RS07210	COG0255	Belongs to the universal ribosomal protein uL29 family
BTR_RS07215	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BTR_RS07220	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BTR_RS07225	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BTR_RS07230	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BTR_RS07235	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BTR_RS07240	COG0089	rRNA binding
BTR_RS07245	COG0088	Forms part of the polypeptide exit tunnel
BTR_RS07250	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BTR_RS07255	COG0051	transcription antitermination factor activity, RNA binding
BTR_RS07260	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BTR_RS07265	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BTR_RS07270	COG0049	tRNA binding
BTR_RS07275	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BTR_RS07280	COG0708	Exodeoxyribonuclease III
BTR_RS07290	COG0765	amino acid transport
BTR_RS07295	COG0765	amino acid transport
BTR_RS07300	COG1126	abc transporter atp-binding protein
BTR_RS07305	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BTR_RS07310	COG0525	valine-tRNA ligase activity
BTR_RS07325	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BTR_RS07340	COG0513	Belongs to the DEAD box helicase family
BTR_RS07350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BTR_RS07360	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTR_RS07370	COG3264	Mechanosensitive ion channel
BTR_RS07370	COG1196	nuclear chromosome segregation
BTR_RS07385	COG4651	solute:proton antiporter activity
BTR_RS07385	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BTR_RS07400	COG1253	flavin adenine dinucleotide binding
BTR_RS07410	COG0179	Fumarylacetoacetate (FAA) hydrolase
BTR_RS07420	COG1113	amino acid transport
BTR_RS07425	COG1113	amino acid transport
BTR_RS07430	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BTR_RS07440	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BTR_RS07445	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BTR_RS07460	COG0028	Belongs to the TPP enzyme family
BTR_RS07465	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BTR_RS07470	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BTR_RS07475	COG0330	HflC and HflK could
BTR_RS07490	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BTR_RS07495	COG0477	Major facilitator Superfamily
BTR_RS07500	COG0477	Major facilitator Superfamily
BTR_RS07505	COG0477	Major facilitator Superfamily
BTR_RS07540	COG1999	signal sequence binding
BTR_RS07550	COG0006	proline dipeptidase activity
BTR_RS07560	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BTR_RS07565	COG0497	DNA recombination
BTR_RS07570	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BTR_RS07585	COG0849	cell division
BTR_RS07595	COG1181	Belongs to the D-alanine--D-alanine ligase family
BTR_RS07600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BTR_RS07605	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BTR_RS07610	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BTR_RS07620	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BTR_RS07625	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BTR_RS07650	COG0275	rRNA processing
BTR_RS07665	COG2226	methyltransferase
BTR_RS07680	COG1335	isochorismatase
BTR_RS07725	COG2968	Membrane
BTR_RS07750	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTR_RS07755	COG0358	DNA primase activity
BTR_RS07760	COG0668	transmembrane transport
BTR_RS07775	COG3161	chorismate lyase activity
BTR_RS07785	COG0505	Belongs to the CarA family
BTR_RS07800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BTR_RS07815	COG0482	sulfurtransferase activity
BTR_RS07985	COG1192	Involved in chromosome partitioning
BTR_RS08000	COG0196	riboflavin kinase activity
BTR_RS08015	COG1396	sequence-specific DNA binding
BTR_RS08025	COG3838	Conjugal transfer protein Trbc
BTR_RS08030	COG3702	type iv secretory pathway
BTR_RS08035	COG3451	type IV secretory pathway VirB4
BTR_RS08045	COG3704	protein secretion by the type IV secretion system
BTR_RS08055	COG3736	Type IV secretory pathway, component VirB8
BTR_RS08060	COG3504	Conjugal transfer protein
BTR_RS08065	COG2948	multi-organism process
BTR_RS08070	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BTR_RS08080	COG2184	nucleotidyltransferase activity
BTR_RS08085	COG3505	Type IV secretory pathway VirD4
BTR_RS08105	COG2184	nucleotidyltransferase activity
BTR_RS08130	COG2184	nucleotidyltransferase activity
BTR_RS08135	COG0728	peptidoglycan biosynthetic process
BTR_RS08140	COG0180	Tryptophanyl-tRNA synthetase
BTR_RS08150	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BTR_RS08155	COG2824	Alkylphosphonate utilization operon protein PhnA
BTR_RS08160	COG0033	Phosphoglucomutase
BTR_RS08175	COG0124	histidyl-tRNA synthetase
BTR_RS08185	COG1396	sequence-specific DNA binding
BTR_RS08195	COG0284	orotidine-5'-phosphate decarboxylase activity
BTR_RS08250	COG0735	belongs to the Fur family
BTR_RS08280	COG1054	Belongs to the UPF0176 family
BTR_RS08285	COG0800	Aldolase
BTR_RS08310	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTR_RS08310	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BTR_RS08315	COG0509	glycine decarboxylation via glycine cleavage system
BTR_RS08320	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BTR_RS08335	COG2835	tetraacyldisaccharide 4'-kinase activity
BTR_RS08340	COG1396	sequence-specific DNA binding
BTR_RS08345	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BTR_RS08360	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BTR_RS08365	COG2011	ABC-type metal ion transport system permease component
BTR_RS08410	COG0523	cobalamin synthesis protein
BTR_RS08420	COG3468	outer membrane autotransporter barrel domain protein
BTR_RS08425	COG3468	outer membrane autotransporter barrel domain protein
BTR_RS08460	COG4607	ABC-type enterochelin transport system periplasmic component
BTR_RS08465	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BTR_RS08470	COG4605	iron ion homeostasis
BTR_RS08475	COG4604	ABC transporter, ATP-binding protein
BTR_RS08595	COG2369	cell adhesion
BTR_RS08600	COG4383	Mu-like prophage protein gp29
BTR_RS08605	COG4373	Mu-like prophage FluMu protein gp28
BTR_RS08640	COG3179	chitinase
BTR_RS08670	COG2842	Transposition protein
BTR_RS08690	COG1475	DNA binding
BTR_RS08745	COG0444	Belongs to the ABC transporter superfamily
BTR_RS08750	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BTR_RS08755	COG0601	transmembrane transport
BTR_RS08760	COG0747	negative chemotaxis
BTR_RS08775	COG0519	Catalyzes the synthesis of GMP from XMP
BTR_RS08780	COG1570	exodeoxyribonuclease VII activity
BTR_RS08830	COG0730	response to heat
BTR_RS08840	COG2086	electron transfer activity
BTR_RS08855	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BTR_RS08860	COG0792	nuclease activity
BTR_RS08880	COG0489	protein tyrosine kinase activity
BTR_RS08885	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BTR_RS08890	COG0594	ribonuclease P activity
BTR_RS08900	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BTR_RS08910	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BTR_RS08915	COG0588	phosphoglycerate mutase activity
BTR_RS08970	COG3023	N-Acetylmuramoyl-L-alanine amidase
BTR_RS08985	COG2814	Major facilitator Superfamily
BTR_RS09055	COG0477	Major facilitator Superfamily
BTR_RS09115	COG3920	Histidine kinase
BTR_RS09130	COG0784	Response regulator, receiver
BTR_RS09275	COG1396	sequence-specific DNA binding
BTR_RS09295	COG1396	sequence-specific DNA binding
BTR_RS09340	COG1396	sequence-specific DNA binding
BTR_RS09350	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BTR_RS09355	COG0424	maF-like protein
BTR_RS09360	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BTR_RS09405	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
BTR_RS09415	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BTR_RS09420	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BTR_RS09435	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BTR_RS09440	COG0457	Tetratricopeptide repeat
BTR_RS09460	COG1396	sequence-specific DNA binding
BTR_RS09465	COG1396	sequence-specific DNA binding
BTR_RS09470	COG1396	sequence-specific DNA binding
BTR_RS09485	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTR_RS09490	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BTR_RS09495	COG1692	metallophosphoesterase
BTR_RS09510	COG0473	3-isopropylmalate dehydrogenase activity
BTR_RS09510	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BTR_RS09525	COG1396	sequence-specific DNA binding
BTR_RS09530	COG1396	sequence-specific DNA binding
BTR_RS09535	COG1396	sequence-specific DNA binding
BTR_RS09540	COG1396	sequence-specific DNA binding
BTR_RS09550	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BTR_RS09925	COG0459	protein refolding
BTR_RS09930	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BTR_RS09945	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BTR_RS10025	COG0741	lytic transglycosylase activity
BTR_RS10060	COG3657	addiction module killer protein
BTR_RS10115	COG0629	single-stranded DNA binding
BTR_RS10185	COG3561	AntA/AntB antirepressor
BTR_RS10210	COG0582	viral genome integration into host DNA
BTR_RS10220	COG1238	metal cluster binding
BTR_RS10260	COG0756	dUTP diphosphatase activity
BTR_RS10280	COG0848	biopolymer transport protein
BTR_RS10285	COG0811	peptide transport
BTR_RS10315	COG3838	Conjugal transfer protein Trbc
BTR_RS10320	COG3702	type iv secretory pathway
BTR_RS10350	COG3704	protein secretion by the type IV secretion system
BTR_RS10360	COG3736	Type IV secretory pathway, component VirB8
BTR_RS10365	COG3504	Conjugal transfer protein
BTR_RS10370	COG2948	multi-organism process
BTR_RS10375	COG0630	type IV secretory pathway, VirB11 components, and related ATPases involved in Archaeal flagella biosynthesis
BTR_RS10425	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTR_RS10430	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BTR_RS10435	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BTR_RS10440	COG0037	tRNA processing
BTR_RS10450	COG2885	chlorophyll binding
BTR_RS10460	COG0217	transcriptional regulatory protein
BTR_RS10480	COG0823	Involved in the tonB-independent uptake of proteins
BTR_RS10500	COG0824	Thioesterase
BTR_RS10505	COG2255	four-way junction helicase activity
BTR_RS10510	COG0632	four-way junction helicase activity
BTR_RS10515	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BTR_RS10565	COG1396	sequence-specific DNA binding
BTR_RS10570	COG1396	sequence-specific DNA binding
BTR_RS10595	COG1396	sequence-specific DNA binding
BTR_RS10600	COG1396	sequence-specific DNA binding
BTR_RS10610	COG1396	sequence-specific DNA binding
BTR_RS10620	COG1396	sequence-specific DNA binding
BTR_RS10630	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BTR_RS10635	COG0483	inositol monophosphate 1-phosphatase activity
BTR_RS10660	COG1132	(ABC) transporter
BTR_RS10665	COG0254	rRNA binding
BTR_RS10680	COG3588	fructose-bisphosphate aldolase
BTR_RS10685	COG0126	phosphoglycerate kinase activity
BTR_RS10710	COG0469	pyruvate kinase activity
BTR_RS10715	COG0469	pyruvate kinase activity
BTR_RS10720	COG0469	pyruvate kinase activity
BTR_RS10725	COG0469	pyruvate kinase activity
BTR_RS10735	COG3750	Belongs to the UPF0335 family
BTR_RS10745	COG0488	(ABC) transporter
BTR_RS10760	COG4783	chaperone-mediated protein folding
BTR_RS10770	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BTR_RS10780	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BTR_RS10795	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTR_RS10805	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTR_RS10810	COG0142	geranyltranstransferase activity
BTR_RS10830	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BTR_RS10845	COG1566	PFAM secretion protein HlyD family protein
BTR_RS10855	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BTR_RS10860	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BTR_RS10865	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BTR_RS10870	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BTR_RS10875	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BTR_RS10915	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BTR_RS10925	COG0495	leucyl-tRNA aminoacylation
BTR_RS10945	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BTR_RS10950	COG2884	Cell division ATP-binding protein ftsE
BTR_RS10975	COG0577	efflux transmembrane transporter activity
BTR_RS10975	COG1136	(ABC) transporter
BTR_RS10980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BTR_RS10985	COG1538	Outer membrane efflux protein
BTR_RS11010	COG1674	ftsk spoiiie
BTR_RS11015	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BTR_RS11165	COG2948	multi-organism process
BTR_RS11220	COG0335	large ribosomal subunit rRNA binding
BTR_RS11225	COG0336	Belongs to the RNA methyltransferase TrmD family
BTR_RS11230	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BTR_RS11270	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BTR_RS11280	COG0138	bifunctional purine biosynthesis protein purh
BTR_RS11295	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BTR_RS11295	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BTR_RS11300	COG0501	Belongs to the peptidase M48B family
BTR_RS11305	COG5508	conserved small protein
BTR_RS11310	COG0228	four-way junction DNA binding
BTR_RS11320	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BTR_RS11325	COG0288	reversible hydration of carbon dioxide
BTR_RS11330	COG2902	Dehydrogenase
BTR_RS11355	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BTR_RS11370	COG0745	RESPONSE REGULATOR receiver
BTR_RS11395	COG0165	Argininosuccinate lyase
BTR_RS11400	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BTR_RS11405	COG1671	Belongs to the UPF0178 family
BTR_RS11415	COG0287	Prephenate dehydrogenase
BTR_RS11425	COG1122	ATPase activity
BTR_RS11555	COG2369	cell adhesion
BTR_RS11560	COG4383	Mu-like prophage protein gp29
BTR_RS11565	COG4373	Mu-like prophage FluMu protein gp28
BTR_RS11600	COG3179	chitinase
BTR_RS11630	COG2842	Transposition protein
BTR_RS11650	COG1475	DNA binding
BTR_RS11690	COG1686	Belongs to the peptidase S11 family
BTR_RS11700	COG0523	cobalamin synthesis protein
BTR_RS11705	COG3034	peptidoglycan biosynthetic process
BTR_RS11710	COG0825	malonyl-CoA metabolic process
BTR_RS11725	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BTR_RS11735	COG3895	Periplasmic Protein
BTR_RS11740	COG1320	monovalent cation:proton antiporter activity
BTR_RS11745	COG2212	antiporter activity
BTR_RS11750	COG1863	multisubunit Na H antiporter MnhE subunit
BTR_RS11755	COG0651	ATP synthesis coupled electron transport
BTR_RS11760	COG1006	Multisubunit Na H antiporter MnhC subunit
BTR_RS11765	COG2111	Na H antiporter
BTR_RS11765	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BTR_RS11775	COG0019	diaminopimelate decarboxylase activity
BTR_RS11790	COG0508	dehydrogenase complex catalyzes the overall conversion of
BTR_RS11795	COG0567	Dehydrogenase, E1 component
BTR_RS11805	COG0045	succinate-CoA ligase (ADP-forming) activity
BTR_RS11810	COG0039	L-malate dehydrogenase activity
BTR_RS11815	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BTR_RS11825	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BTR_RS11830	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BTR_RS11835	COG0552	protein localization to endoplasmic reticulum
BTR_RS11845	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BTR_RS11870	COG0357	Ribosomal RNA small subunit methyltransferase G
BTR_RS11875	COG0445	tRNA wobble uridine modification
BTR_RS11880	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BTR_RS11885	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BTR_RS12025	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BTR_RS12065	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BTR_RS12085	COG0333	Belongs to the bacterial ribosomal protein bL32 family