locus-tag	class	description
IX83_RS00005	COG0445	tRNA wobble uridine modification
IX83_RS00010	COG0357	Ribosomal RNA small subunit methyltransferase G
IX83_RS00015	COG1192	Involved in chromosome partitioning
IX83_RS00040	COG0405	Gamma-glutamyltransferase
IX83_RS00045	COG1247	-acetyltransferase
IX83_RS00050	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
IX83_RS00055	COG0443	Heat shock 70 kDa protein
IX83_RS00060	COG0484	heat shock protein binding
IX83_RS00065	COG0730	response to heat
IX83_RS00075	COG4221	oxidoreductase activity
IX83_RS00090	COG0733	neurotransmitter:sodium symporter activity
IX83_RS00095	COG0471	metal ion transport
IX83_RS00105	COG0753	catalase activity
IX83_RS00110	COG0706	membrane insertase activity
IX83_RS00120	COG0594	ribonuclease P activity
IX83_RS00125	COG0230	Belongs to the bacterial ribosomal protein bL34 family
IX83_RS00130	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IX83_RS00145	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
IX83_RS00150	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
IX83_RS00155	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
IX83_RS00210	COG1442	glycosyl transferase family 8
IX83_RS00215	COG0463	Glycosyl transferase, family 2
IX83_RS00225	COG3306	glycosyltransferase involved in LPS biosynthesis
IX83_RS00230	COG1216	Glycosyl transferase, family 2
IX83_RS00245	COG1442	glycosyl transferase family 8
IX83_RS00250	COG3306	glycosyltransferase involved in LPS biosynthesis
IX83_RS00260	COG3384	dioxygenase
IX83_RS00295	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
IX83_RS00300	COG2423	ornithine cyclodeaminase activity
IX83_RS00305	COG0477	Major facilitator Superfamily
IX83_RS00310	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IX83_RS00325	COG0010	Belongs to the arginase family
IX83_RS00340	COG3313	Fe-S protein
IX83_RS00350	COG0814	amino acid
IX83_RS00355	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
IX83_RS00360	COG0049	tRNA binding
IX83_RS00365	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
IX83_RS00375	COG0051	transcription antitermination factor activity, RNA binding
IX83_RS00380	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
IX83_RS00385	COG1854	S-ribosylhomocysteine lyase activity
IX83_RS00415	COG2814	Major facilitator Superfamily
IX83_RS00425	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
IX83_RS00430	COG0735	belongs to the Fur family
IX83_RS00435	COG1121	(ABC) transporter
IX83_RS00440	COG1108	ABC-type Mn2 Zn2 transport systems permease components
IX83_RS00460	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
IX83_RS00465	COG2945	thiolester hydrolase activity
IX83_RS00470	COG1686	Belongs to the peptidase S11 family
IX83_RS00480	COG2921	Belongs to the UPF0250 family
IX83_RS00490	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
IX83_RS00500	COG0463	Glycosyl transferase, family 2
IX83_RS00505	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
IX83_RS00515	COG3177	Filamentation induced by cAMP protein fic
IX83_RS00525	COG3177	Filamentation induced by cAMP protein fic
IX83_RS00535	COG0500	methyltransferase
IX83_RS00560	COG1733	regulation of RNA biosynthetic process
IX83_RS00565	COG2910	NAD(P)H-binding
IX83_RS00575	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
IX83_RS00580	COG2828	Protein conserved in bacteria
IX83_RS00585	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
IX83_RS00590	COG0372	Belongs to the citrate synthase family
IX83_RS00595	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
IX83_RS00610	COG0018	arginyl-trna synthetase
IX83_RS00620	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
IX83_RS00625	COG3209	COG3209 Rhs family protein
IX83_RS00635	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
IX83_RS00645	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
IX83_RS00655	COG2271	Major facilitator Superfamily
IX83_RS00660	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IX83_RS00665	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
IX83_RS00675	COG0089	rRNA binding
IX83_RS00680	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
IX83_RS00685	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
IX83_RS00690	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
IX83_RS00695	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
IX83_RS00700	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
IX83_RS00705	COG0255	Belongs to the universal ribosomal protein uL29 family
IX83_RS00710	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
IX83_RS00730	COG2423	ornithine cyclodeaminase activity
IX83_RS00735	COG1408	metallophosphoesterase
IX83_RS00740	COG2814	Major facilitator Superfamily
IX83_RS00750	COG0232	Belongs to the dGTPase family. Type 2 subfamily
IX83_RS00755	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
IX83_RS00770	COG2519	Catalyzes the S-adenosyl-L-methionine-dependent formation of N(1)-methyladenine at position 58 (m1A58) in tRNA
IX83_RS00775	COG2223	nitrite transmembrane transporter activity
IX83_RS00780	COG0708	Exodeoxyribonuclease III
IX83_RS00790	COG1970	mechanosensitive ion channel activity
IX83_RS00795	COG0723	plastoquinol--plastocyanin reductase activity
IX83_RS00800	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
IX83_RS00805	COG2857	Cytochrome c1
IX83_RS00810	COG0625	glutathione transferase activity
IX83_RS00845	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
IX83_RS00850	COG2890	protein-(glutamine-N5) methyltransferase activity
IX83_RS00855	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
IX83_RS00890	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
IX83_RS00895	COG0166	Belongs to the GPI family
IX83_RS00910	COG1946	Acyl-CoA thioesterase
IX83_RS00915	COG1253	flavin adenine dinucleotide binding
IX83_RS00920	COG2246	polysaccharide biosynthetic process
IX83_RS00930	COG0390	transport system, permease component
IX83_RS00935	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IX83_RS00940	COG0242	peptide deformylase activity
IX83_RS00945	COG0758	DNA mediated transformation
IX83_RS00950	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
IX83_RS00955	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
IX83_RS00960	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IX83_RS00960	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IX83_RS00970	COG5000	phosphorelay sensor kinase activity
IX83_RS00975	COG2204	response regulator
IX83_RS00985	COG1040	competence protein
IX83_RS00990	COG2226	methyltransferase
IX83_RS00995	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
IX83_RS01000	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
IX83_RS01005	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
IX83_RS01010	COG0588	phosphoglycerate mutase activity
IX83_RS01015	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
IX83_RS01025	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX83_RS01035	COG0218	Necessary for normal cell division and for the maintenance of normal septation
IX83_RS01050	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
IX83_RS01055	COG1965	Belongs to the frataxin family
IX83_RS01065	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
IX83_RS01075	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IX83_RS01080	COG0154	amidase activity
IX83_RS01085	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
IX83_RS01090	COG1077	Cell shape determining protein MreB Mrl
IX83_RS01095	COG1792	Involved in formation and maintenance of cell shape
IX83_RS01105	COG0768	penicillin binding
IX83_RS01110	COG0772	Belongs to the SEDS family
IX83_RS01115	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
IX83_RS01120	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX83_RS01135	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX83_RS01140	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
IX83_RS01145	COG1660	Displays ATPase and GTPase activities
IX83_RS01150	COG0792	nuclease activity
IX83_RS01155	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
IX83_RS01165	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IX83_RS01180	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
IX83_RS01205	COG1137	ATPase activity
IX83_RS01210	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
IX83_RS01215	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
IX83_RS01220	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
IX83_RS01225	COG1984	allophanate hydrolase subunit 2
IX83_RS01230	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
IX83_RS01235	COG5002	protein histidine kinase activity
IX83_RS01255	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
IX83_RS01260	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
IX83_RS01265	COG1132	(ABC) transporter
IX83_RS01270	COG0346	lactoylglutathione lyase activity
IX83_RS01280	COG2233	PERMEase
IX83_RS01285	COG0385	Bile acid
IX83_RS01290	COG5383	Protein conserved in bacteria
IX83_RS01295	COG1012	belongs to the aldehyde dehydrogenase family
IX83_RS01300	COG1757	Na H antiporter
IX83_RS01305	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX83_RS01320	COG1393	Belongs to the ArsC family
IX83_RS01330	COG4106	trans-aconitate 2-methyltransferase activity
IX83_RS01350	COG2878	Part of a membrane complex involved in electron transport
IX83_RS01355	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
IX83_RS01365	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
IX83_RS01375	COG0251	oxidation-reduction process
IX83_RS01380	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX83_RS01390	COG0159	tryptophan synthase activity
IX83_RS01395	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
IX83_RS01415	COG4651	solute:proton antiporter activity
IX83_RS01415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
IX83_RS01430	COG3241	Transfers electrons from cytochrome c551 to cytochrome oxidase
IX83_RS01480	COG4604	ABC transporter, ATP-binding protein
IX83_RS01485	COG4605	iron ion homeostasis
IX83_RS01490	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
IX83_RS01495	COG4607	ABC-type enterochelin transport system periplasmic component
IX83_RS01505	COG0523	cobalamin synthesis protein
IX83_RS01515	COG1994	Peptidase M50
IX83_RS01525	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
IX83_RS01530	COG0488	(ABC) transporter
IX83_RS01535	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IX83_RS01540	COG0850	regulation of cytokinetic process
IX83_RS01550	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
IX83_RS01555	COG2894	cell division
IX83_RS01565	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
IX83_RS01570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
IX83_RS01575	COG0210	DNA helicase
IX83_RS01580	COG3245	cytochrome
IX83_RS01595	COG1012	belongs to the aldehyde dehydrogenase family
IX83_RS01600	COG2303	Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate
IX83_RS01610	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX83_RS01615	COG0765	amino acid transport
IX83_RS01625	COG0037	tRNA processing
IX83_RS01645	COG2851	Citrate transporter
IX83_RS01650	COG0497	DNA recombination
IX83_RS01660	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
IX83_RS01670	COG2188	Transcriptional regulator
IX83_RS01685	COG1053	succinate dehydrogenase
IX83_RS01690	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
IX83_RS01695	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
IX83_RS01700	COG0372	Belongs to the citrate synthase family
IX83_RS01710	COG4178	(ABC) transporter
IX83_RS01720	COG0741	lytic transglycosylase activity
IX83_RS01725	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
IX83_RS01750	COG3022	response to hydroperoxide
IX83_RS01755	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
IX83_RS01760	COG2183	response to ionizing radiation
IX83_RS01770	COG1199	ATP-dependent helicase activity
IX83_RS01775	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX83_RS01780	COG0564	pseudouridine synthase activity
IX83_RS01790	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
IX83_RS01795	COG0335	large ribosomal subunit rRNA binding
IX83_RS01810	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX83_RS01815	COG1636	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
IX83_RS01825	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
IX83_RS01840	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
IX83_RS01850	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
IX83_RS01855	COG0505	Belongs to the CarA family
IX83_RS01860	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
IX83_RS01865	COG0436	Aminotransferase
IX83_RS01870	COG3162	membrane
IX83_RS01875	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX83_RS01880	COG0567	Dehydrogenase, E1 component
IX83_RS01885	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX83_RS01890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX83_RS01895	COG2831	hemolysin activation secretion protein
IX83_RS01900	COG3210	domain, Protein
IX83_RS01930	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
IX83_RS01935	COG0343	queuine tRNA-ribosyltransferase activity
IX83_RS01940	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
IX83_RS01945	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
IX83_RS01955	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
IX83_RS01960	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
IX83_RS01965	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
IX83_RS01970	COG0009	L-threonylcarbamoyladenylate synthase
IX83_RS01985	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
IX83_RS01990	COG0494	nUDIX hydrolase
IX83_RS02000	COG0142	geranyltranstransferase activity
IX83_RS02005	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX83_RS02010	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX83_RS02015	COG0765	amino acid transport
IX83_RS02020	COG1126	abc transporter atp-binding protein
IX83_RS02025	COG0129	dihydroxy-acid dehydratase activity
IX83_RS02035	COG0261	This protein binds to 23S rRNA in the presence of protein L20
IX83_RS02040	COG0211	Belongs to the bacterial ribosomal protein bL27 family
IX83_RS02045	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
IX83_RS02050	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
IX83_RS02055	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
IX83_RS02060	COG0352	thiamine-phosphate diphosphorylase activity
IX83_RS02065	COG1773	rubredoxin
IX83_RS02070	COG1678	Uncharacterized ACR, COG1678
IX83_RS02085	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
IX83_RS02100	COG0827	DNA restriction-modification system
IX83_RS02130	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
IX83_RS02160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
IX83_RS02165	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IX83_RS02165	COG4776	Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction
IX83_RS02175	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IX83_RS02180	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
IX83_RS02185	COG0511	ligase activity, forming carbon-carbon bonds
IX83_RS02195	COG2264	protein methyltransferase activity
IX83_RS02205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
IX83_RS02215	COG2194	sulfuric ester hydrolase activity
IX83_RS02220	COG0859	PFAM glycosyl transferase family 9
IX83_RS02230	COG0425	Belongs to the sulfur carrier protein TusA family
IX83_RS02235	COG2391	methyltransferase activity
IX83_RS02240	COG2070	2-Nitropropane dioxygenase
IX83_RS02245	COG0583	DNA-binding transcription factor activity
IX83_RS02250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
IX83_RS02265	COG2001	Belongs to the MraZ family
IX83_RS02270	COG0275	rRNA processing
IX83_RS02290	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
IX83_RS02295	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
IX83_RS02300	COG0772	Belongs to the SEDS family
IX83_RS02305	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
IX83_RS02310	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
IX83_RS02315	COG1181	Belongs to the D-alanine--D-alanine ligase family
IX83_RS02320	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
IX83_RS02335	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
IX83_RS02345	COG0745	RESPONSE REGULATOR receiver
IX83_RS02350	COG0642	Histidine kinase
IX83_RS02355	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
IX83_RS02395	COG0495	leucyl-tRNA aminoacylation
IX83_RS02405	COG3278	Belongs to the heme-copper respiratory oxidase family
IX83_RS02435	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
IX83_RS02440	COG0542	response to heat
IX83_RS02445	COG0604	alcohol dehydrogenase
IX83_RS02450	COG0149	triose-phosphate isomerase activity
IX83_RS02495	COG0492	ferredoxin-NADP+ reductase activity
IX83_RS02500	COG1674	ftsk spoiiie
IX83_RS02505	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IX83_RS02510	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
IX83_RS02575	COG0616	signal peptide processing
IX83_RS02590	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
IX83_RS02595	COG0316	Belongs to the HesB IscA family
IX83_RS02605	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
IX83_RS02610	COG1881	PFAM PEBP family protein
IX83_RS02615	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
IX83_RS02620	COG2239	Acts as a magnesium transporter
IX83_RS02630	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
IX83_RS02630	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
IX83_RS02640	COG2119	membrane
IX83_RS02645	COG0418	dihydroorotase activity
IX83_RS02650	COG4122	O-methyltransferase activity
IX83_RS02655	COG4566	intracellular signal transduction
IX83_RS02665	COG0248	Ppx GppA phosphatase
IX83_RS02670	COG2081	HI0933 family
IX83_RS02675	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
IX83_RS02690	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
IX83_RS02705	COG0513	Belongs to the DEAD box helicase family
IX83_RS02715	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
IX83_RS02765	COG0284	orotidine-5'-phosphate decarboxylase activity
IX83_RS02770	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
IX83_RS02780	COG1666	GTP binding
IX83_RS02795	COG3210	domain, Protein
IX83_RS02800	COG0268	Binds directly to 16S ribosomal RNA
IX83_RS02805	COG0728	peptidoglycan biosynthetic process
IX83_RS02810	COG0563	adenylate kinase activity
IX83_RS02815	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
IX83_RS02820	COG1663	tetraacyldisaccharide 4'-kinase activity
IX83_RS02825	COG0305	Participates in initiation and elongation during chromosome replication
IX83_RS02830	COG1686	Belongs to the peptidase S11 family
IX83_RS02835	COG0047	phosphoribosylformylglycinamidine synthase activity
IX83_RS02835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
IX83_RS02845	COG0518	GMP synthase (glutamine-hydrolyzing) activity
IX83_RS02845	COG0519	Catalyzes the synthesis of GMP from XMP
IX83_RS02850	COG2863	cytochrome
IX83_RS02855	COG3258	Cytochrome c
IX83_RS02860	COG1115	amino acid carrier protein
IX83_RS02940	COG2197	response regulator
IX83_RS03005	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
IX83_RS03010	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
IX83_RS03065	COG1292	Belongs to the BCCT transporter (TC 2.A.15) family
IX83_RS03070	COG2814	Major facilitator Superfamily
IX83_RS03080	COG0220	tRNA (guanine-N7-)-methyltransferase activity
IX83_RS03095	COG0489	protein tyrosine kinase activity
IX83_RS03110	COG0717	Belongs to the dCTP deaminase family
IX83_RS03135	COG1045	serine acetyltransferase
IX83_RS03160	COG0134	indole-3-glycerol-phosphate synthase activity
IX83_RS03165	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
IX83_RS03170	COG0512	Glutamine amidotransferase of anthranilate synthase
IX83_RS03180	COG0546	phosphoglycolate phosphatase activity
IX83_RS03185	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
IX83_RS03195	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
IX83_RS03200	COG1765	OsmC-like protein
IX83_RS03205	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
IX83_RS03220	COG0277	FAD linked oxidase domain protein
IX83_RS03245	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
IX83_RS03250	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
IX83_RS03255	COG0193	aminoacyl-tRNA hydrolase activity
IX83_RS03270	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IX83_RS03305	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
IX83_RS03310	COG0742	ribosomal rna small subunit methyltransferase
IX83_RS03330	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
IX83_RS03335	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IX83_RS03340	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
IX83_RS03345	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
IX83_RS03355	COG0668	transmembrane transport
IX83_RS03360	COG0210	DNA helicase
IX83_RS03360	COG0210	DNA helicase
IX83_RS03370	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
IX83_RS03375	COG0196	riboflavin kinase activity
IX83_RS03380	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
IX83_RS03385	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
IX83_RS03385	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
IX83_RS03390	COG0210	DNA helicase
IX83_RS03400	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
IX83_RS03415	COG1760	l-serine dehydratase
IX83_RS03425	COG0826	peptidase U32
IX83_RS03445	COG5295	Hep Hag repeat protein
IX83_RS03450	COG1136	(ABC) transporter
IX83_RS03450	COG0577	efflux transmembrane transporter activity
IX83_RS03455	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX83_RS03460	COG1385	rRNA (uridine-N3-)-methyltransferase activity
IX83_RS03465	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
IX83_RS03470	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
IX83_RS03475	COG1063	alcohol dehydrogenase
IX83_RS03480	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
IX83_RS03495	COG0544	peptidyl-prolyl cis-trans isomerase activity
IX83_RS03500	COG0740	serine-type endopeptidase activity
IX83_RS03505	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
IX83_RS03510	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
IX83_RS03515	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
IX83_RS03520	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
IX83_RS03530	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
IX83_RS03535	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
IX83_RS03540	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IX83_RS03560	COG1722	exodeoxyribonuclease VII activity
IX83_RS03565	COG0142	geranyltranstransferase activity
IX83_RS03575	COG1469	GTP cyclohydrolase I activity
IX83_RS03580	COG0360	Binds together with S18 to 16S ribosomal RNA
IX83_RS03585	COG2965	DNA replication, synthesis of RNA primer
IX83_RS03590	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
IX83_RS03595	COG0359	binds to the 23S rRNA
IX83_RS03600	COG3106	COG3106 Predicted ATPase
IX83_RS03610	COG3842	ATPase activity
IX83_RS03615	COG0395	ABC-type sugar transport system, permease component
IX83_RS03620	COG1175	transmembrane transport
IX83_RS03630	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
IX83_RS03640	COG0339	signal peptide processing
IX83_RS03645	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
IX83_RS03670	COG3158	transport of potassium into the cell
IX83_RS03675	COG0598	Magnesium transport protein CorA
IX83_RS03685	COG0626	cystathionine gamma-synthase activity
IX83_RS03690	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
IX83_RS03705	COG1136	(ABC) transporter
IX83_RS03710	COG0404	The glycine cleavage system catalyzes the degradation of glycine
IX83_RS03715	COG0509	glycine decarboxylation via glycine cleavage system
IX83_RS03720	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IX83_RS03720	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
IX83_RS03735	COG2056	Na+-H+ antiporter family
IX83_RS03750	COG0356	it plays a direct role in the translocation of protons across the membrane
IX83_RS03760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
IX83_RS03765	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
IX83_RS03770	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
IX83_RS03775	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
IX83_RS03780	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
IX83_RS03785	COG0355	proton-transporting ATP synthase activity, rotational mechanism
IX83_RS03800	COG3566	protein conserved in bacteria
IX83_RS03810	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
IX83_RS03815	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
IX83_RS03835	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
IX83_RS03840	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IX83_RS03855	COG1902	pentaerythritol trinitrate reductase activity
IX83_RS03885	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
IX83_RS03915	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
IX83_RS03935	COG1840	ABC-type Fe3 transport system, periplasmic component
IX83_RS03945	COG3842	ATPase activity
IX83_RS03950	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX83_RS03950	COG0543	2 iron, 2 sulfur cluster binding
IX83_RS03960	COG0613	PHP domain protein
IX83_RS03970	COG0584	glycerophosphoryl diester phosphodiesterase
IX83_RS03975	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
IX83_RS03980	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX83_RS03985	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
IX83_RS03990	COG1758	RNA polymerase activity
IX83_RS03995	COG0194	GDP metabolic process
IX83_RS04000	COG0586	Pfam SNARE associated Golgi protein
IX83_RS04010	COG1561	YicC-like family, N-terminal region
IX83_RS04015	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
IX83_RS04020	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
IX83_RS04025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IX83_RS04040	COG2833	Protein of unknown function (DUF455)
IX83_RS04045	COG4178	(ABC) transporter
IX83_RS04050	COG0730	response to heat
IX83_RS04055	COG0557	exoribonuclease II activity
IX83_RS04060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX83_RS04065	COG0776	regulation of translation
IX83_RS04085	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
IX83_RS04090	COG0508	dehydrogenase complex catalyzes the overall conversion of
IX83_RS04095	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
IX83_RS04100	COG0285	dihydrofolate synthase activity
IX83_RS04140	COG0024	Methionine aminopeptidase
IX83_RS04145	COG0052	Belongs to the universal ribosomal protein uS2 family
IX83_RS04150	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
IX83_RS04160	COG0528	UMP kinase activity
IX83_RS04165	COG0233	cytoplasmic translational termination
IX83_RS04170	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
IX83_RS04175	COG0575	Belongs to the CDS family
IX83_RS04185	COG0750	zinc metalloprotease
IX83_RS04200	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX83_RS04205	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
IX83_RS04210	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX83_RS04215	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX83_RS04220	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
IX83_RS04230	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
IX83_RS04235	COG0084	hydrolase, TatD family'
IX83_RS04245	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
IX83_RS04275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
IX83_RS04280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
IX83_RS04285	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
IX83_RS04290	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
IX83_RS04295	COG0330	HflC and HflK could
IX83_RS04300	COG0330	HflC and HflK could
IX83_RS04305	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
IX83_RS04310	COG1923	regulation of RNA biosynthetic process
IX83_RS04315	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
IX83_RS04320	COG1160	GTP binding
IX83_RS04325	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX83_RS04330	COG2976	Protein conserved in bacteria
IX83_RS04350	COG0820	rRNA (adenine-C2-)-methyltransferase activity
IX83_RS04355	COG0105	UTP biosynthetic process
IX83_RS04360	COG0525	valine-tRNA ligase activity
IX83_RS04375	COG3909	cytochrome
IX83_RS04385	COG0482	sulfurtransferase activity
IX83_RS04390	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
IX83_RS04395	COG0312	modulator of DNA gyrase
IX83_RS04400	COG0308	aminopeptidase N
IX83_RS04405	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
IX83_RS04420	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
IX83_RS04425	COG0748	coenzyme F420 binding
IX83_RS04430	COG0778	Nitroreductase
IX83_RS04450	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
IX83_RS04455	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
IX83_RS04460	COG0354	folic acid binding
IX83_RS04465	COG0084	hydrolase, TatD family'
IX83_RS04470	COG0633	Ferredoxin
IX83_RS04475	COG0443	Heat shock 70 kDa protein
IX83_RS04480	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
IX83_RS04485	COG0316	Belongs to the HesB IscA family
IX83_RS04490	COG0822	iron-sulfur transferase activity
IX83_RS04495	COG1104	cysteine desulfurase activity
IX83_RS04515	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
IX83_RS04520	COG0228	four-way junction DNA binding
IX83_RS04530	COG0793	Belongs to the peptidase S41A family
IX83_RS04535	COG2951	lytic endotransglycosylase activity
IX83_RS04550	COG3058	Necessary for formate dehydrogenase activity
IX83_RS04555	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
IX83_RS04560	COG2864	formate dehydrogenase
IX83_RS04565	COG0437	4 iron, 4 sulfur cluster binding
IX83_RS04570	COG0243	molybdopterin cofactor binding
IX83_RS04570	COG3383	formate dehydrogenase (NAD+) activity
IX83_RS04595	COG0583	DNA-binding transcription factor activity
IX83_RS04600	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
IX83_RS04610	COG2204	response regulator
IX83_RS04620	COG0174	glutamine synthetase
IX83_RS04630	COG1289	transmembrane transporter activity
IX83_RS04650	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
IX83_RS04655	COG1560	Kdo2-lipid A biosynthetic process
IX83_RS04660	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
IX83_RS04670	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
IX83_RS04700	COG1477	protein flavinylation
IX83_RS04730	COG1373	ATPase (AAA superfamily
IX83_RS04740	COG0270	DNA (cytosine-5-)-methyltransferase activity
IX83_RS04750	COG4160	amino acid transport
IX83_RS04755	COG4215	(ABC) transporter
IX83_RS04760	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
IX83_RS04770	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
IX83_RS04775	COG2137	regulation of response to DNA damage stimulus
IX83_RS04795	COG0556	nucleotide-excision repair
IX83_RS04805	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
IX83_RS04820	COG0151	Belongs to the GarS family
IX83_RS04825	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
IX83_RS04830	COG0799	negative regulation of ribosome biogenesis
IX83_RS04835	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
IX83_RS04840	COG0424	maF-like protein
IX83_RS04845	COG0515	serine threonine protein kinase
IX83_RS04850	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
IX83_RS04855	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
IX83_RS04875	COG0181	hydroxymethylbilane synthase activity
IX83_RS04880	COG0861	Integral membrane protein TerC family
IX83_RS04885	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
IX83_RS04890	COG0045	succinate-CoA ligase (ADP-forming) activity
IX83_RS04895	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
IX83_RS04900	COG4149	molybdate abc transporter
IX83_RS04905	COG0725	ABC transporter, periplasmic molybdate-binding protein
IX83_RS04910	COG0425	Belongs to the sulfur carrier protein TusA family
IX83_RS04915	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
IX83_RS04925	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
IX83_RS04930	COG1525	nuclease
IX83_RS04935	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
IX83_RS04940	COG0527	aspartate kinase activity
IX83_RS04960	COG1966	Carbon starvation protein
IX83_RS04970	COG1132	(ABC) transporter
IX83_RS04990	COG1643	Atp-dependent helicase
IX83_RS04995	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
IX83_RS04995	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
IX83_RS05000	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
IX83_RS05005	COG0704	Plays a role in the regulation of phosphate uptake
IX83_RS05010	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
IX83_RS05015	COG1177	transmembrane transport
IX83_RS05020	COG1176	ABC-type spermidine putrescine transport system, permease component I
IX83_RS05025	COG3842	ATPase activity
IX83_RS05040	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
IX83_RS05050	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
IX83_RS05065	COG0436	Aminotransferase
IX83_RS05075	COG1280	lysine exporter protein (LysE YggA)
IX83_RS05080	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
IX83_RS05085	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
IX83_RS05100	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
IX83_RS05105	COG0756	dUTP diphosphatase activity
IX83_RS05110	COG1278	Cold shock
IX83_RS05120	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
IX83_RS05125	COG0778	Nitroreductase
IX83_RS05130	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
IX83_RS05140	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
IX83_RS05145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
IX83_RS05150	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
IX83_RS05160	COG2984	ABC transporter substrate binding protein
IX83_RS05165	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
IX83_RS05175	COG1619	proteins homologs of microcin C7 resistance protein MccF
IX83_RS05185	COG0314	molybdopterin synthase activity
IX83_RS05195	COG0746	molybdenum cofactor guanylyltransferase activity
IX83_RS05200	COG0521	Mo-molybdopterin cofactor biosynthetic process
IX83_RS05205	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
IX83_RS05210	COG0303	'Molybdopterin
IX83_RS05215	COG2223	nitrite transmembrane transporter activity
IX83_RS05225	COG2181	nitrate reductase activity
IX83_RS05230	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
IX83_RS05235	COG1140	nitrate reductase beta subunit
IX83_RS05240	COG5013	Belongs to the prokaryotic molybdopterin-containing oxidoreductase family
IX83_RS05245	COG3850	Histidine kinase
IX83_RS05250	COG2197	response regulator
IX83_RS05260	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
IX83_RS05265	COG1047	Peptidyl-prolyl cis-trans
IX83_RS05275	COG0254	rRNA binding
IX83_RS05280	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
IX83_RS05305	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
IX83_RS05310	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IX83_RS05325	COG1187	pseudouridine synthase activity
IX83_RS05335	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX83_RS05335	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
IX83_RS05340	COG0165	Argininosuccinate lyase
IX83_RS05350	COG0534	Mate efflux family protein
IX83_RS05355	COG0227	Belongs to the bacterial ribosomal protein bL28 family
IX83_RS05360	COG0267	Belongs to the bacterial ribosomal protein bL33 family
IX83_RS05375	COG0601	transmembrane transport
IX83_RS05380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
IX83_RS05390	COG2169	Transcriptional regulator
IX83_RS05390	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
IX83_RS05400	COG0825	malonyl-CoA metabolic process
IX83_RS05405	COG0122	3-methyladenine DNA glycosylase 8-oxoguanine DNA glycosylase
IX83_RS05410	COG0215	cysteine-tRNA ligase activity
IX83_RS05420	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
IX83_RS05425	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
IX83_RS05430	COG1968	undecaprenyl-diphosphatase activity
IX83_RS05435	COG0483	inositol monophosphate 1-phosphatase activity
IX83_RS05445	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
IX83_RS05450	COG2850	peptidyl-arginine hydroxylation
IX83_RS05490	COG1337	RAMP superfamily
IX83_RS05510	COG0442	prolyl-tRNA aminoacylation
IX83_RS05515	COG0494	nUDIX hydrolase
IX83_RS05530	COG0824	Thioesterase
IX83_RS05535	COG0811	peptide transport
IX83_RS05540	COG0848	biopolymer transport protein
IX83_RS05550	COG0823	Involved in the tonB-independent uptake of proteins
IX83_RS05570	COG0135	phosphoribosylanthranilate isomerase activity
IX83_RS05575	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
IX83_RS05585	COG0101	tRNA pseudouridine synthase activity
IX83_RS05595	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
IX83_RS05600	COG0473	3-isopropylmalate dehydrogenase activity
IX83_RS05615	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
IX83_RS05625	COG1295	ribonuclease BN
IX83_RS05640	COG1858	cytochrome C peroxidase
IX83_RS05665	COG2814	Major facilitator Superfamily
IX83_RS05675	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
IX83_RS05680	COG0126	phosphoglycerate kinase activity
IX83_RS05690	COG1570	exodeoxyribonuclease VII activity
IX83_RS05710	COG0514	ATP-dependent DNA helicase (RecQ)
IX83_RS05715	COG0277	FAD linked oxidase domain protein
IX83_RS05720	COG1596	polysaccharide export
IX83_RS05720	COG1555	photosystem II stabilization
IX83_RS05725	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
IX83_RS05730	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
IX83_RS05735	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
IX83_RS05740	COG0776	regulation of translation
IX83_RS05750	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
IX83_RS05760	COG0077	Prephenate dehydratase
IX83_RS05760	COG1605	Chorismate mutase
IX83_RS05765	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
IX83_RS05785	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
IX83_RS05795	COG1115	amino acid carrier protein
IX83_RS05805	COG2951	lytic endotransglycosylase activity
IX83_RS05810	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
IX83_RS05815	COG2252	PERMEase
IX83_RS05860	COG0501	Belongs to the peptidase M48B family
IX83_RS05865	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX83_RS05865	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
IX83_RS05875	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
IX83_RS05880	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
IX83_RS05900	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX83_RS05905	COG3914	O-linked N-acetylglucosamine transferase SPINDLY family
IX83_RS05915	COG0653	protein targeting
IX83_RS05940	COG0110	maltose O-acetyltransferase activity
IX83_RS05960	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
IX83_RS05970	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
IX83_RS05975	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
IX83_RS05980	COG1534	Rna-binding protein
IX83_RS05985	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
IX83_RS06010	COG2917	probably involved in intracellular septation
IX83_RS06015	COG2259	Doxx family
IX83_RS06020	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
IX83_RS06035	COG2171	N-acyltransferase activity
IX83_RS06040	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
IX83_RS06045	COG2890	protein-(glutamine-N5) methyltransferase activity
IX83_RS06050	COG0488	(ABC) transporter
IX83_RS06070	COG1304	FMN binding
IX83_RS06075	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IX83_RS06080	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
IX83_RS06085	COG0312	modulator of DNA gyrase
IX83_RS06090	COG3028	Belongs to the UPF0307 family
IX83_RS06100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
IX83_RS06110	COG0477	Major facilitator Superfamily
IX83_RS06135	COG0167	dihydroorotate dehydrogenase activity
IX83_RS06145	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX83_RS06150	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX83_RS06165	COG1546	Belongs to the CinA family
IX83_RS06165	COG1058	Belongs to the CinA family
IX83_RS06170	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
IX83_RS06180	COG1196	nuclear chromosome segregation
IX83_RS06185	COG0477	Major facilitator Superfamily
IX83_RS06190	COG4974	Belongs to the 'phage' integrase family
IX83_RS06195	COG0802	atpase or kinase
IX83_RS06200	COG0860	N-Acetylmuramoyl-L-alanine amidase
IX83_RS06205	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
IX83_RS06210	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
IX83_RS06215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
IX83_RS06220	COG0617	tRNA 3'-terminal CCA addition
IX83_RS06230	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
IX83_RS06235	COG0628	permease
IX83_RS06250	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
IX83_RS06255	COG0751	glycine-tRNA ligase activity
IX83_RS06260	COG0752	glycyl-tRNA synthetase alpha subunit
IX83_RS06270	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
IX83_RS06275	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
IX83_RS06280	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
IX83_RS06305	COG5002	protein histidine kinase activity
IX83_RS06335	COG2326	polyphosphate kinase activity
IX83_RS06340	COG0351	phosphomethylpyrimidine kinase
IX83_RS06345	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
IX83_RS06355	COG0009	L-threonylcarbamoyladenylate synthase
IX83_RS06360	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
IX83_RS06365	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IX83_RS06370	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
IX83_RS06375	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IX83_RS06380	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
IX83_RS06395	COG0488	(ABC) transporter
IX83_RS06400	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
IX83_RS06405	COG0237	dephospho-CoA kinase activity
IX83_RS06410	COG0670	Belongs to the BI1 family
IX83_RS06420	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
IX83_RS06450	COG1368	sulfuric ester hydrolase activity
IX83_RS06460	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX83_RS06465	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
IX83_RS06470	COG1862	Preprotein translocase
IX83_RS06475	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
IX83_RS06480	COG1702	phosphate starvation-inducible protein PhoH
IX83_RS06490	COG4535	Mg2 and Co2 transporter CorC
IX83_RS06495	COG0815	Transfers the fatty acyl group on membrane lipoproteins
IX83_RS06525	COG0179	Fumarylacetoacetate (FAA) hydrolase
IX83_RS06540	COG0589	response to stress
IX83_RS06550	COG0697	spore germination
IX83_RS06560	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
IX83_RS06570	COG1388	LysM domain
IX83_RS06570	COG0741	lytic transglycosylase activity
IX83_RS06585	COG0328	RNA-DNA hybrid ribonuclease activity
IX83_RS06590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
IX83_RS06595	COG0735	belongs to the Fur family
IX83_RS06600	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
IX83_RS06610	COG0812	UDP-N-acetylmuramate dehydrogenase activity
IX83_RS06640	COG2089	acid synthase
IX83_RS06645	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
IX83_RS06660	COG2358	TRAP transporter, solute receptor (TAXI family
IX83_RS06670	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
IX83_RS06675	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
IX83_RS06680	COG0138	bifunctional purine biosynthesis protein purh
IX83_RS06695	COG2255	four-way junction helicase activity
IX83_RS06700	COG0632	four-way junction helicase activity
IX83_RS06705	COG0514	ATP-dependent DNA helicase (RecQ)
IX83_RS06710	COG2022	thiamine diphosphate biosynthetic process
IX83_RS06725	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
IX83_RS06730	COG2814	Major facilitator Superfamily
IX83_RS06760	COG0697	spore germination
IX83_RS06765	COG3093	addiction module antidote protein HigA
IX83_RS06815	COG0741	lytic transglycosylase activity
IX83_RS06900	COG1484	DNA-dependent DNA replication
IX83_RS06960	COG0629	single-stranded DNA binding
IX83_RS07020	COG0307	riboflavin synthase, alpha
IX83_RS07025	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX83_RS07025	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
IX83_RS07035	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
IX83_RS07040	COG0148	phosphopyruvate hydratase activity
IX83_RS07045	COG2877	3-deoxy-8-phosphooctulonate synthase activity
IX83_RS07050	COG0504	CTP synthase activity
IX83_RS07070	COG0252	asparaginase activity
IX83_RS07080	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
IX83_RS07085	COG0322	excinuclease ABC activity
IX83_RS07090	COG1472	Belongs to the glycosyl hydrolase 3 family
IX83_RS07095	COG0736	holo-[acyl-carrier-protein] synthase activity
IX83_RS07100	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
IX83_RS07105	COG1162	GTPase activity
IX83_RS07115	COG0330	HflC and HflK could
IX83_RS07125	COG1185	polyribonucleotide nucleotidyltransferase activity
IX83_RS07130	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
IX83_RS07135	COG1183	phosphatidylcholine synthase activity
IX83_RS07140	COG0688	phosphatidylethanolamine metabolic process
IX83_RS07150	COG2217	Heavy metal translocating P-type atpase
IX83_RS07160	COG1217	gtp-binding protein TYPA
IX83_RS07165	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
IX83_RS07170	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
IX83_RS07175	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
IX83_RS07180	COG2251	uridine kinase activity
IX83_RS07180	COG0195	Participates in both transcription termination and antitermination
IX83_RS07185	COG0779	Required for maturation of 30S ribosomal subunits
IX83_RS07190	COG1187	pseudouridine synthase activity
IX83_RS07195	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
IX83_RS07210	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
IX83_RS07215	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
IX83_RS07230	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
IX83_RS07245	COG3023	N-Acetylmuramoyl-L-alanine amidase
IX83_RS07255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
IX83_RS07270	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
IX83_RS07275	COG0440	acetolactate synthase activity
IX83_RS07280	COG0028	Belongs to the TPP enzyme family
IX83_RS07295	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
IX83_RS07300	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
IX83_RS07305	COG0776	regulation of translation
IX83_RS07310	COG0072	phenylalanine-tRNA ligase activity
IX83_RS07310	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
IX83_RS07315	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
IX83_RS07320	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
IX83_RS07325	COG0291	Belongs to the bacterial ribosomal protein bL35 family
IX83_RS07330	COG3306	glycosyltransferase involved in LPS biosynthesis
IX83_RS07340	COG0606	chelatase, subunit chli
IX83_RS07355	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
IX83_RS07360	COG0259	pyridoxamine-phosphate oxidase activity
IX83_RS07365	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
IX83_RS07385	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
IX83_RS07385	COG4451	ribulose bisphosphate carboxylase, small
IX83_RS07395	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
IX83_RS07425	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
IX83_RS07435	COG1007	ATP synthesis coupled electron transport
IX83_RS07450	COG0713	ATP synthesis coupled electron transport
IX83_RS07460	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IX83_RS07465	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
IX83_RS07470	COG1034	ATP synthesis coupled electron transport
IX83_RS07480	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
IX83_RS07485	COG0649	NAD binding
IX83_RS07490	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IX83_RS07495	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IX83_RS07500	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
IX83_RS07505	COG3256	nitric oxide reductase
IX83_RS07520	COG3133	Outer membrane lipoprotein
IX83_RS07535	COG1999	signal sequence binding
IX83_RS07590	COG3210	domain, Protein
IX83_RS07595	COG2831	hemolysin activation secretion protein
IX83_RS07605	COG2837	iron assimilation
IX83_RS07630	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
IX83_RS07635	COG2363	Small membrane protein
IX83_RS07640	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
IX83_RS07655	COG0540	Belongs to the ATCase OTCase family
IX83_RS07665	COG1126	abc transporter atp-binding protein
IX83_RS07670	COG0765	amino acid transport
IX83_RS07675	COG4597	amino acid ABC transporter
IX83_RS07685	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
IX83_RS07690	COG1194	a g-specific adenine glycosylase
IX83_RS07695	COG1381	Involved in DNA repair and RecF pathway recombination
IX83_RS07700	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
IX83_RS07705	COG0571	ribonuclease III activity
IX83_RS07720	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
IX83_RS07745	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IX83_RS07750	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IX83_RS07755	COG1028	Short-chain dehydrogenase reductase Sdr
IX83_RS07760	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
IX83_RS07765	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
IX83_RS07770	COG0416	fatty acid biosynthetic process
IX83_RS07775	COG0333	Belongs to the bacterial ribosomal protein bL32 family
IX83_RS07780	COG1399	metal-binding, possibly nucleic acid-binding protein
IX83_RS07785	COG0424	maF-like protein
IX83_RS07795	COG1530	ribonuclease E activity
IX83_RS07815	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IX83_RS07820	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
IX83_RS07850	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
IX83_RS07870	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IX83_RS07885	COG1028	Short-chain dehydrogenase reductase Sdr
IX83_RS07890	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
IX83_RS07930	COG3210	domain, Protein
IX83_RS07935	COG2831	hemolysin activation secretion protein
IX83_RS07950	COG1473	amidohydrolase
IX83_RS07955	COG1126	abc transporter atp-binding protein
IX83_RS07960	COG0765	amino acid transport
IX83_RS07965	COG0765	amino acid transport
IX83_RS07980	COG0203	ribosomal protein L17
IX83_RS07985	COG0202	RNA polymerase activity
IX83_RS07990	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
IX83_RS07995	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
IX83_RS08000	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
IX83_RS08010	COG0201	protein transport
IX83_RS08015	COG0200	Binds to the 23S rRNA
IX83_RS08020	COG1841	ribosomal large subunit assembly
IX83_RS08025	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
IX83_RS08030	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
IX83_RS08040	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
IX83_RS08045	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
IX83_RS08050	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
IX83_RS08055	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
IX83_RS08060	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
IX83_RS08065	COG1448	Aminotransferase
IX83_RS08070	COG3633	Involved in the import of serine and threonine into the cell, with the concomitant import of sodium (symport system)
IX83_RS08080	COG0720	synthase
IX83_RS08110	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
IX83_RS08115	COG0140	phosphoribosyl-ATP diphosphatase activity
IX83_RS08120	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
IX83_RS08125	COG0107	imidazoleglycerol-phosphate synthase activity
IX83_RS08135	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
IX83_RS08140	COG0131	Imidazoleglycerol-phosphate dehydratase
IX83_RS08145	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
IX83_RS08150	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
IX83_RS08155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
IX83_RS08165	COG0842	Transport permease protein
IX83_RS08170	COG1131	(ABC) transporter
IX83_RS08175	COG2854	intermembrane phospholipid transfer
IX83_RS08180	COG2853	Lipoprotein
IX83_RS08185	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
IX83_RS08190	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
IX83_RS08195	COG1127	ABC transporter
IX83_RS08205	COG0070	glutamate synthase
IX83_RS08205	COG0069	glutamate synthase activity
IX83_RS08205	COG0067	glutamate synthase
IX83_RS08210	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
IX83_RS08230	COG2011	ABC-type metal ion transport system permease component
IX83_RS08240	COG0625	glutathione transferase activity
IX83_RS08250	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
IX83_RS08270	COG1322	Protein conserved in bacteria
IX83_RS08310	COG1464	Belongs to the NlpA lipoprotein family
IX83_RS08315	COG2011	ABC-type metal ion transport system permease component
IX83_RS08320	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
IX83_RS08330	COG0635	Involved in the biosynthesis of porphyrin-containing compound
IX83_RS08340	COG4232	protein-disulfide reductase activity
IX83_RS08345	COG1324	tolerance protein
IX83_RS08360	COG2194	sulfuric ester hydrolase activity
IX83_RS08375	COG0786	glutamate:sodium symporter activity
IX83_RS08380	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
IX83_RS08385	COG0085	RNA polymerase activity
IX83_RS08390	COG0222	ribosome binding
IX83_RS08395	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
IX83_RS08400	COG0081	regulation of translation
IX83_RS08405	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
IX83_RS08460	COG0583	DNA-binding transcription factor activity
IX83_RS08480	COG1215	transferase activity, transferring glycosyl groups
IX83_RS08485	COG2814	Major facilitator Superfamily
IX83_RS08505	COG2830	Protein of unknown function (DUF452)
IX83_RS08515	COG3161	chorismate lyase activity
IX83_RS08525	COG2840	Smr protein MutS2
IX83_RS08555	COG4104	PAAR repeat-containing protein
IX83_RS08610	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
IX83_RS08620	COG3477	response to acidic pH
IX83_RS08635	COG0791	NLP P60 protein
IX83_RS08680	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
IX83_RS08685	COG1846	Transcriptional regulator
IX83_RS08690	COG1216	Glycosyl transferase, family 2
IX83_RS08725	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes