locus-tag	class	description
BCI_RS00010	COG0047	phosphoribosylformylglycinamidine synthase activity
BCI_RS00010	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCI_RS00025	COG0483	inositol monophosphate 1-phosphatase activity
BCI_RS00045	COG0124	histidyl-tRNA synthetase
BCI_RS00050	COG1520	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCI_RS00070	COG0494	nUDIX hydrolase
BCI_RS00080	COG0583	DNA-binding transcription factor activity
BCI_RS00095	COG1897	L-methionine biosynthetic process from homoserine via O-succinyl-L-homoserine and cystathionine
BCI_RS00105	COG0180	Tryptophanyl-tRNA synthetase
BCI_RS00110	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCI_RS00125	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCI_RS00130	COG0586	Pfam SNARE associated Golgi protein
BCI_RS00135	COG5007	Belongs to the BolA IbaG family
BCI_RS00145	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCI_RS00150	COG3105	Protein conserved in bacteria
BCI_RS00185	COG0071	Belongs to the small heat shock protein (HSP20) family
BCI_RS00190	COG0330	HflC and HflK could
BCI_RS00210	COG0352	thiamine-phosphate diphosphorylase activity
BCI_RS00215	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BCI_RS00220	COG2104	thiamine diphosphate biosynthetic process
BCI_RS00235	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
BCI_RS00240	COG1792	Involved in formation and maintenance of cell shape
BCI_RS00245	COG1077	Cell shape determining protein MreB Mrl
BCI_RS00250	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCI_RS00255	COG0511	ligase activity, forming carbon-carbon bonds
BCI_RS00260	COG0439	Biotin carboxylase
BCI_RS00275	COG0306	phosphate transporter
BCI_RS00280	COG0552	protein localization to endoplasmic reticulum
BCI_RS00285	COG2884	Cell division ATP-binding protein ftsE
BCI_RS00290	COG2177	Part of the ABC transporter FtsEX involved in
BCI_RS00315	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BCI_RS00345	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCI_RS00360	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCI_RS00365	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BCI_RS00370	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCI_RS00375	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
BCI_RS00385	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BCI_RS00390	COG4208	sulfate ABC transporter
BCI_RS00400	COG2878	Part of a membrane complex involved in electron transport
BCI_RS00405	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCI_RS00415	COG1846	Transcriptional regulator
BCI_RS00425	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BCI_RS00430	COG0307	riboflavin synthase, alpha
BCI_RS00465	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCI_RS00470	COG0716	FMN binding
BCI_RS00475	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BCI_RS00485	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCI_RS00495	COG2885	chlorophyll binding
BCI_RS00500	COG1729	Mediates coordination of peptidoglycan synthesis and outer membrane constriction during cell division
BCI_RS00505	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BCI_RS00510	COG0037	tRNA processing
BCI_RS00515	COG0025	NhaP-type Na H and K H
BCI_RS00520	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCI_RS00540	COG1846	Transcriptional regulator
BCI_RS00555	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BCI_RS00565	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCI_RS00565	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCI_RS00570	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCI_RS00590	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BCI_RS00595	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCI_RS00625	COG1011	Hydrolase
BCI_RS00635	COG0598	Magnesium transport protein CorA
BCI_RS00645	COG0187	DNA topoisomerase II activity
BCI_RS00670	COG0706	membrane insertase activity
BCI_RS00740	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BCI_RS00745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCI_RS00755	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BCI_RS00805	COG0626	cystathionine gamma-synthase activity
BCI_RS00815	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BCI_RS00835	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BCI_RS00845	COG1045	serine acetyltransferase
BCI_RS00855	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BCI_RS00860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCI_RS00865	COG4942	peptidase
BCI_RS00870	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCI_RS00890	COG1561	YicC-like family, N-terminal region
BCI_RS00905	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BCI_RS00935	COG3118	belongs to the thioredoxin family
BCI_RS00940	COG3085	chromosome segregation
BCI_RS00945	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCI_RS00950	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCI_RS00955	COG0564	pseudouridine synthase activity
BCI_RS00960	COG0542	response to heat
BCI_RS00985	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BCI_RS01020	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCI_RS01025	COG0765	amino acid transport
BCI_RS01035	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCI_RS01050	COG2895	sulfate adenylyltransferase (ATP) activity
BCI_RS01080	COG0720	synthase
BCI_RS01085	COG0602	queuosine metabolic process
BCI_RS01100	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCI_RS01115	COG1734	Transcription factor that acts by binding directly to the RNA polymerase (RNAP). Required for negative regulation of rRNA expression and positive regulation of several amino acid biosynthesis promoters
BCI_RS01120	COG0617	tRNA 3'-terminal CCA addition
BCI_RS01125	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BCI_RS01145	COG1466	dna polymerase III delta subunit
BCI_RS01155	COG0768	penicillin binding
BCI_RS01160	COG0772	Belongs to the SEDS family
BCI_RS01180	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCI_RS01200	COG2706	6-phosphogluconolactonase activity
BCI_RS01205	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCI_RS01215	COG0156	8-amino-7-oxononanoate synthase activity
BCI_RS01220	COG2226	methyltransferase
BCI_RS01230	COG1126	abc transporter atp-binding protein
BCI_RS01250	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCI_RS01255	COG0539	negative regulation of cytoplasmic translation
BCI_RS01310	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCI_RS01315	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCI_RS01320	COG1845	cytochrome c oxidase, subunit III
BCI_RS01325	COG3125	oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
BCI_RS01335	COG2814	Major facilitator Superfamily
BCI_RS01345	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BCI_RS01345	COG0301	tRNA thio-modification
BCI_RS01350	COG0142	geranyltranstransferase activity
BCI_RS01375	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BCI_RS01380	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCI_RS01385	COG0571	ribonuclease III activity
BCI_RS01405	COG0525	valine-tRNA ligase activity
BCI_RS01410	COG2927	DNA polymerase III (CHI subunit)
BCI_RS01420	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BCI_RS01425	COG2890	protein-(glutamine-N5) methyltransferase activity
BCI_RS01455	COG0012	GTP binding
BCI_RS01475	COG3771	Involved in the assembly of lipopolysaccharide (LPS)
BCI_RS01500	COG2350	Protein conserved in bacteria
BCI_RS01505	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BCI_RS01510	COG2916	Histone family protein nucleoid-structuring protein H-NS
BCI_RS01520	COG1528	Iron-storage protein
BCI_RS01525	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BCI_RS01530	COG0469	pyruvate kinase activity
BCI_RS01535	COG1914	H( )-stimulated, divalent metal cation uptake system
BCI_RS01575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BCI_RS01580	COG1674	ftsk spoiiie
BCI_RS01580	COG3107	peptidoglycan biosynthetic process
BCI_RS01585	COG0492	ferredoxin-NADP+ reductase activity
BCI_RS01595	COG1126	abc transporter atp-binding protein
BCI_RS01600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCI_RS01605	COG4215	(ABC) transporter
BCI_RS01610	COG4160	amino acid transport
BCI_RS01695	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCI_RS01720	COG0201	protein transport
BCI_RS01775	COG1072	(Pantothenic acid kinase))
BCI_RS01780	COG2890	protein-(glutamine-N5) methyltransferase activity
BCI_RS01790	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BCI_RS01810	COG0285	dihydrofolate synthase activity
BCI_RS01815	COG1286	toxin biosynthetic process
BCI_RS01820	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BCI_RS01830	COG1008	NDH-1 shuttles electrons from NAD(P)H, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be plastoquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCI_RS01835	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCI_RS01845	COG0839	Belongs to the complex I subunit 6 family
BCI_RS01860	COG1034	ATP synthesis coupled electron transport
BCI_RS01865	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BCI_RS01895	COG0280	phosphate acetyltransferase
BCI_RS01895	COG0857	belongs to the CobB CobQ family
BCI_RS01900	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BCI_RS01910	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCI_RS01935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BCI_RS01940	COG0791	NLP P60 protein
BCI_RS01950	COG0833	amino acid
BCI_RS01975	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BCI_RS01975	COG0140	phosphoribosyl-ATP diphosphatase activity
BCI_RS02005	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCI_RS02015	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCI_RS02020	COG1448	Aminotransferase
BCI_RS02040	COG1067	ATP-dependent peptidase activity
BCI_RS02050	COG2920	part of a sulfur-relay system
BCI_RS02075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCI_RS02080	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCI_RS02080	COG0674	pyruvate-flavodoxin oxidoreductase activity
BCI_RS02080	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BCI_RS02080	COG1013	pyruvate-flavodoxin oxidoreductase activity
BCI_RS02085	COG0114	fumarate hydratase activity
BCI_RS02100	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCI_RS02105	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCI_RS02110	COG1136	(ABC) transporter
BCI_RS02115	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCI_RS02120	COG3417	Regulator of peptidoglycan synthesis that is essential for the function of penicillin-binding protein 1B (PBP1b)
BCI_RS02125	COG0537	adenosine 5'-monophosphoramidase activity
BCI_RS02130	COG0084	hydrolase, TatD family'
BCI_RS02135	COG0470	DNA polymerase III
BCI_RS02145	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCI_RS02175	COG0564	pseudouridine synthase activity
BCI_RS02180	COG1530	ribonuclease E activity
BCI_RS02185	COG0418	dihydroorotase activity
BCI_RS02190	COG0616	signal peptide processing
BCI_RS02205	COG2894	cell division
BCI_RS02220	COG1376	ErfK ybiS ycfS ynhG family protein
BCI_RS02225	COG3716	PTS system mannose fructose sorbose family IID component
BCI_RS02230	COG3715	PTS system
BCI_RS02235	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BCI_RS02235	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCI_RS02240	COG1253	flavin adenine dinucleotide binding
BCI_RS02275	COG2814	Major facilitator Superfamily
BCI_RS02280	COG1566	PFAM secretion protein HlyD family protein
BCI_RS02285	COG2166	iron-sulfur cluster assembly
BCI_RS02290	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCI_RS02295	COG0719	Fe-S assembly protein
BCI_RS02300	COG0396	ATPase activity
BCI_RS02305	COG0719	Fe-S assembly protein
BCI_RS02310	COG0316	Belongs to the HesB IscA family
BCI_RS02315	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCI_RS02315	COG0072	phenylalanine-tRNA ligase activity
BCI_RS02320	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCI_RS02335	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCI_RS02345	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BCI_RS02360	COG3021	interspecies interaction between organisms
BCI_RS02365	COG0741	lytic transglycosylase activity
BCI_RS02375	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BCI_RS02390	COG0189	ligase activity
BCI_RS02395	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BCI_RS02420	COG0735	belongs to the Fur family
BCI_RS02425	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BCI_RS02430	COG2923	Belongs to the DsrF TusC family
BCI_RS02435	COG2168	tRNA wobble position uridine thiolation
BCI_RS02460	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCI_RS02465	COG0250	Participates in transcription elongation, termination and antitermination
BCI_RS02530	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCI_RS02535	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCI_RS02540	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BCI_RS02545	COG0157	Belongs to the NadC ModD family
BCI_RS02585	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCI_RS02590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BCI_RS02595	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCI_RS02640	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCI_RS02645	COG0575	Belongs to the CDS family
BCI_RS02655	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCI_RS02660	COG2825	PFAM Outer membrane chaperone Skp (OmpH)
BCI_RS02670	COG0587	DNA-directed DNA polymerase activity
BCI_RS02680	COG0626	cystathionine gamma-synthase activity
BCI_RS02685	COG3066	DNA modification
BCI_RS02705	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
BCI_RS02710	COG1074	ATP-dependent DNA helicase activity
BCI_RS02715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BCI_RS02745	COG0484	heat shock protein binding
BCI_RS02755	COG0196	riboflavin kinase activity
BCI_RS02765	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BCI_RS02775	COG0505	Belongs to the CarA family
BCI_RS02780	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCI_RS02785	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCI_RS02800	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BCI_RS02810	COG2913	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BCI_RS02815	COG2914	Belongs to the UPF0125 (RnfH) family
BCI_RS02825	COG1218	3'(2'),5'-bisphosphate nucleotidase
BCI_RS02850	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCI_RS02855	COG0557	exoribonuclease II activity
BCI_RS02865	COG0330	HflC and HflK could
BCI_RS02870	COG0330	HflC and HflK could
BCI_RS02875	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCI_RS02920	COG1509	lysine 2,3-aminomutase activity
BCI_RS02945	COG0450	alkyl hydroperoxide reductase
BCI_RS02960	COG1862	Preprotein translocase
BCI_RS02965	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCI_RS02970	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCI_RS02975	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCI_RS02975	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BCI_RS02990	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BCI_RS02995	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BCI_RS03000	COG0729	surface antigen
BCI_RS03005	COG2911	Protein conserved in bacteria
BCI_RS03010	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCI_RS03025	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BCI_RS03035	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BCI_RS03040	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCI_RS03055	COG0358	DNA primase activity
BCI_RS03070	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCI_RS03095	COG3050	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The exact function of the psi subunit is
BCI_RS03100	COG0513	Belongs to the DEAD box helicase family
BCI_RS03130	COG0195	Participates in both transcription termination and antitermination
BCI_RS03145	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCI_RS03155	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCI_RS03175	COG2027	D-alanyl-D-alanine carboxypeptidase
BCI_RS03210	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BCI_RS03215	COG0351	phosphomethylpyrimidine kinase
BCI_RS03225	COG0517	IMP dehydrogenase activity
BCI_RS03225	COG0516	GMP reductase activity
BCI_RS03250	COG4238	major outer membrane lipoprotein