locus_tag old_locus_tag gene Name start end strand product note type ID NCBI WP_011520690.1 546863 547561 + 30S ribosomal protein S2 CDS cds484 http://www.ncbi.nlm.nih.gov/gene/?term= BCI_RS00005 BCI_0001 BCI_RS00005 197 1720 + malate:quinone oxidoreductase gene gene0 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00005 BCI_RS00010 BCI_0002 BCI_RS00010 1933 5826 + phosphoribosylformylglycinamidine synthase catalyzes the formation of 2-(formamido)-N1-(5-phospho-D-ribosyl)acetamidine from N2-formyl-N1-(5-phospho-D-ribosyl)glycinamide and L-glutamine in purine biosynthesis gene gene1 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00010 BCI_RS00015 BCI_0003 BCI_RS00015 5853 6356 + tRNA adenosine deaminase gene gene2 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00015 BCI_RS00020 BCI_0004 BCI_RS00020 6569 7822 + serine hydroxymethyltransferase gene gene3 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00020 BCI_RS00025 BCI_0005 BCI_RS00025 7855 8661 - inositol monophosphatase gene gene4 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00025 BCI_RS00030 BCI_0006 BCI_RS00030 8964 10118 + cysteine desulfurase catalyzes the removal of elemental sulfur from cysteine to produce alanine%3B involved in NAD biosynthesis gene gene5 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00030 BCI_RS00035 BCI_0007 BCI_RS00035 10151 10585 + nucleoside diphosphate kinase catalyzes the formation of nucleoside triphosphate from ATP and nucleoside diphosphate gene gene6 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00035 BCI_RS00040 BCI_0008 BCI_RS00040 10933 12054 + 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (flavodoxin) gene gene7 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00040 BCI_RS00045 BCI_0009 hisS hisS 12077 13369 + histidyl-tRNA synthetase catalyzes a two-step reaction%2C first charging a histidine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B class II aminoacyl-tRNA synthetase%3B forms homodimers%3B some organisms have a paralogous gene%2C hisZ%2C that is similar to hisS and produces a protein that performs the first step in histidine biosynthesis along with HisG gene gene8 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00045 BCI_RS00050 BCI_0010 BCI_RS00050 13440 14615 + outer membrane biogenesis protein BamB gene gene9 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00050 BCI_RS00055 BCI_0011 BCI_RS00055 14634 16052 + GTPase Der gene gene10 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00055 BCI_RS00060 BCI_0012 pgi pgi 16150 17811 + glucose-6-phosphate isomerase functions in sugar metabolism in glycolysis and the Embden-Meyerhof pathways (EMP) and in gluconeogenesis%3B catalyzes reversible isomerization of glucose-6-phosphate to fructose-6-phosphate%3B member of PGI family gene gene11 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00060 BCI_RS00065 BCI_0013 BCI_RS00065 18124 19740 - phosphoenolpyruvate carboxykinase [ATP] PEP carboxykinase%3B PEP carboxylase%3B PEPCK%3B catalyzes the phosphorylation and decarboxylation of oxaloacetate to form phosphoenolpyruvate using ATP gene gene12 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00065 BCI_RS00070 BCI_0014 nudE nudE 20049 20594 + ADP-ribose diphosphatase ADP-sugar pyrophosphatase%3B catalyzes the formation of D-ribose 5-phosphate from ADP-ribose%3B can also act on ADP-mannose and ADP-glucose gene gene13 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00070 BCI_RS00075 BCI_0015 BCI_RS00075 20778 21935 + S-adenosylmethionine synthase catalyzes the formation of S-adenosylmethionine from methionine and ATP%3B methionine adenosyltransferase gene gene14 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00075 BCI_RS00080 BCI_0016 BCI_RS00080 21979 22887 - transcriptional regulator homocysteine-binding%3B positive regulator of metA%2C metE and metH gene gene15 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00080 BCI_RS00085 BCI_0017 BCI_RS00085 22990 25284 + 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase gene gene16 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00085 BCI_RS00090 BCI_0018 BCI_RS00090 25559 27043 + DNA recombination protein RmuC YigN%3B nuclease that may cleave DNA structures arising during the recombination of short-inverted repeats and thereby prevents the inversion of the internal sequence%3B transcription is induced by DNA-damaging agents such as nalidixic acid or mitomycin C in a LexA-dependent manner gene gene17 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00090 BCI_RS00095 BCI_0019 BCI_RS00095 27142 28062 - homoserine O-succinyltransferase catalyzes the formation of O-succinyl-L-homoserine from succinyl-CoA and L-homoserine in methionine biosynthesis gene gene18 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00095 BCI_RS00100 BCI_0020 BCI_RS00100 28316 30781 - glycerol-3-phosphate acyltransferase PlsB%3B catalyzes the formation of 1-acyl-sn-glycerol 3-phosphate by transfering the acyl moiety from acyl-CoA gene gene19 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00100 BCI_RS00105 BCI_0021 BCI_RS00105 30959 31963 - tryptophanyl-tRNA synthetase gene gene20 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00105 BCI_RS00110 BCI_0022 BCI_RS00110 32055 32744 - ribulose-phosphate 3-epimerase gene gene21 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00110 BCI_RS00115 BCI_0023 aroB aroB 32844 33923 - 3-dehydroquinate synthase catalyzes the formation of 3-dehydroquinate from 3-deoxy-arabino-heptulonate 7-phosphate%3B functions in aromatic amino acid biosynthesis gene gene22 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00115 BCI_RS00120 BCI_0024 aroK aroK 33928 34449 - shikimate kinase type I enzyme similar to type II but differentially regulated%3B major shikimate kinase in fully repressed cells%3B catalyzes the formation of shikimate 3-phosphate from shikimate in aromatic amino acid biosynthesis gene gene23 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00120 BCI_RS00125 BCI_0025 pssA pssA 34736 36097 - phosphatidylserine synthase catalyzes de novo synthesis of phosphatidylserine from CDP-diacylglycerol and L-serine which leads eventually to the production of phosphatidylethanolamine%3B bounds to the ribosome gene gene24 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00125 BCI_RS00130 BCI_0026 BCI_RS00130 36278 36928 - membrane protein gene gene25 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00130 BCI_RS00135 BCI_0027 BCI_RS00135 38198 38455 + hypothetical protein gene gene27 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00135 BCI_RS00140 BCI_0028 BCI_RS00140 38523 39779 + UDP-N-acetylglucosamine 1-carboxyvinyltransferase gene gene28 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00140 BCI_RS00145 BCI_0029 BCI_RS00145 39828 41210 - serine endoprotease gene gene29 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00145 BCI_RS00150 BCI_0030 BCI_RS00150 41305 41712 - hypothetical protein gene gene30 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00150 BCI_RS00155 BCI_0031 BCI_RS00155 41948 42376 + 50S ribosomal protein L13 gene gene31 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00155 BCI_RS00160 BCI_0032 BCI_RS00160 42396 42794 + 30S ribosomal protein S9 gene gene32 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00160 BCI_RS00165 BCI_0033 BCI_RS00165 43254 43748 + membrane protein gene gene33 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00165 BCI_RS00170 BCI_RS00170 BCI_RS00170 44259 45114 + glmZ(sRNA)-inactivating NTPase glucosamine-6-phosphate regulated%3B inactivates the glmS upregulator glmZ gene gene34 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00170 BCI_RS00175 BCI_0035 purH purH 45160 46740 + bifunctional purine biosynthesis protein PurH involved in de novo purine biosynthesis gene gene35 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00175 BCI_RS00180 BCI_0036 BCI_RS00180 46761 48035 + phosphoribosylamine--glycine ligase catalyzes the formation of N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-D-ribosylamine and glycine in purine biosynthesis gene gene36 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00180 BCI_RS00185 BCI_0037 BCI_RS00185 48145 48624 - heat-shock protein gene gene37 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00185 BCI_RS00190 BCI_0038 BCI_RS00190 48741 49643 - protease gene gene38 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00190 BCI_RS00195 BCI_0039 BCI_RS00195 49666 50199 - endonuclease gene gene39 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00195 BCI_RS00200 BCI_0040 BCI_RS00200 50301 50585 - transcriptional regulator gene gene40 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00200 BCI_RS00205 BCI_0041 BCI_RS00205 51358 53226 + phosphomethylpyrimidine synthase catalyzes the formation of 4-amino-2-methyl-5-phosphomethylpyrimidine from 5-amino-1-(5-phospho-D-ribosyl)imidazole and S-adenosyl-L-methionine in thiamine biosynthesis gene gene41 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00205 BCI_RS00210 BCI_0042 BCI_RS00210 53213 53857 + thiamine-phosphate pyrophosphorylase catalyzes the formation of thiamine monophosphate from 4-methyl-5-(beta-hydroxyethyl)-thiazole monophosphate and 4-amino-5-hydroxymethyl pyrimidine pyrophosphate gene gene42 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00210 BCI_RS00215 BCI_0043 BCI_RS00215 53850 54623 + molybdopterin biosynthesis protein MoeB gene gene43 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00215 BCI_RS00220 BCI_0044 BCI_RS00220 54623 54823 + thiamine biosynthesis protein ThiS gene gene44 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00220 BCI_RS00225 BCI_0045 BCI_RS00225 54827 55606 + thiazole synthase gene gene45 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00225 BCI_RS00230 BCI_0046 thiH thiH 55603 56751 + thiamine biosynthesis protein ThiH in Escherichia coli this enzyme functions in thiamine biosynthesis along with thiFSGI and iscS%3B with ThiFSG catalyzes the formation of thiazole phosphate from tyrosine%2C cysteine and 1-deoxy-D-xylulose-5-phosphate%3B forms a complex with ThiG%3B contains an iron-sulfur center gene gene46 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00230 BCI_RS00235 BCI_0047 BCI_RS00235 56812 57288 - rod shape-determining protein MreD gene gene47 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00235 BCI_RS00240 BCI_0048 BCI_RS00240 57447 58313 - rod shape-determining protein MreC gene gene48 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00240 BCI_RS00245 BCI_0049 BCI_RS00245 58348 59391 - rod shape-determining protein Mbl gene gene49 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00245 BCI_RS00250 BCI_0050 BCI_RS00250 59798 60250 + 3-dehydroquinate dehydratase catalyzes the formation of 3-dehydroshikimate from 3-dehydroquinate in chorismate biosynthesis gene gene50 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00250 BCI_RS00255 BCI_0051 BCI_RS00255 60272 60724 + acetyl-CoA carboxylase biotin carboxyl carrier protein subunit gene gene51 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00255 BCI_RS00260 BCI_0052 BCI_RS00260 60733 62082 + acetyl-CoA carboxylase biotin carboxylase subunit an AccC homodimer forms the biotin carboxylase subunit of the acetyl CoA carboxylase%2C an enzyme that catalyzes the formation of malonyl-CoA%2C which in turn controls the rate of fatty acid metabolism gene gene52 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00260 BCI_RS00265 BCI_0053 BCI_RS00265 62339 62974 - membrane protein gene gene53 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00265 BCI_RS00270 BCI_0054 BCI_RS00270 63371 65458 + oligopeptidase A gene gene54 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00270 BCI_RS00275 BCI_0055 BCI_RS00275 65455 66972 - phosphate transporter PitA involved in the transport of inorganic phosphate gene gene55 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00275 BCI_RS00280 BCI_0056 BCI_RS00280 67592 68656 + signal recognition particle-docking protein FtsY gene gene56 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00280 BCI_RS00285 BCI_0057 BCI_RS00285 68669 69310 + cell division protein FtsE ATP-binding protein of an ATP-binding cassette transporter%3B when bound to FtsX%2C FtsEX localizes to the cell division site and plays a role in the assembly or stability of the septal ring under low-salt growth conditions gene gene57 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00285 BCI_RS00290 BCI_0058 ftsX ftsX 69330 70280 + cell division protein FtsX ABC transporter%2C membrane protein gene gene58 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00290 BCI_RS00295 BCI_0059 BCI_RS00295 70343 71203 + RNA polymerase factor sigma-32 binds with the catalytic core of RNA polymerase to produce the holoenzyme%3B this sigma factor is responsible for the expression of heat shock promoters gene gene59 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00295 BCI_RS00300 BCI_0060 fre fre 71376 72095 + FMN reductase NAD(P)H-flavin reductase%3B catalyzes the reversible oxidation/reduction of NAD(P) and flavine mononucleotide%3B in Salmonella and E. coli this protein also reduces aquacob(III)alamin to cob(II)alamin gene gene60 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00300 BCI_RS00305 BCI_0061 hemC hemC 72230 73165 + porphobilinogen deaminase transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis gene gene61 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00305 BCI_RS00310 BCI_0062 hemD hemD 73173 73913 + uroporphyrinogen III methyltransferase catalyzes the formation of uroporphyrinogen-III from hydroxymethylbilane%3B functions in tetrapyrrole and heme biosynthesis gene gene62 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00310 BCI_RS00315 BCI_0063 lnt lnt 73928 75448 - apolipoprotein N-acyltransferase Transfers the fatty acyl group on membrane lipoproteins gene gene63 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00315 BCI_RS00320 BCI_0064 BCI_RS00320 75494 75961 - endoribonuclease YbeY gene gene64 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00320 BCI_RS00325 BCI_0065 BCI_RS00325 76001 77356 - tRNA-2-methylthio-N(6)-dimethylallyladenosine synthase catalyzes the formation of 2-methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine from N6-(dimethylallyl)adenosine (i(6)A) gene gene65 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00325 BCI_RS00330 BCI_0066 ligA ligA 77544 79559 - DNA ligase this protein catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction%3B essential for DNA replication and repair of damaged DNA%3B similar to ligase LigB gene gene66 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00330 BCI_RS00340 BCI_0068 BCI_RS00340 80668 81633 + cysteine synthase A gene gene68 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00340 BCI_RS00345 BCI_0069 BCI_RS00345 81807 82064 + PTS sugar transporter gene gene69 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00345 BCI_RS00350 BCI_0070 BCI_RS00350 82117 83832 + phosphoenolpyruvate-protein phosphotransferase Phosphotransferase system%2C enzyme I%3B transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein%3B part of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS)%2C a major carbohydrate active-transport system gene gene70 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00350 BCI_RS00355 BCI_0071 BCI_RS00355 84144 84857 - phosphoribosylaminoimidazole-succinocarboxamide synthase catalyzes the formation of (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate and L-aspartate in purine biosynthesis%3B SAICAR synthase gene gene71 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00355 BCI_RS00360 BCI_0072 BCI_RS00360 85423 86463 + phosphoribosylaminoimidazole synthetase catalyzes the formation of 1-(5-phosphoribosyl)-5-aminoimidazole from 2-(formamido)-N1-(5-phosphoribosyl)acetamidine and ATP in purine biosynthesis gene gene72 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00360 BCI_RS00365 BCI_0073 purN purN 86460 87113 + phosphoribosylglycinamide formyltransferase glycinamide ribonucleotide transformylase%3B GAR Tfase%3B catalyzes the synthesis of 5'-phosphoribosylformylglycinamide from 5'-phosphoribosylglycinamide and 10-formyltetrahydrofolate%3B PurN requires formyl folate for the reaction unlike PurT which uses formate gene gene73 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00365 BCI_RS00370 BCI_0074 BCI_RS00370 87324 89411 + polyphosphate kinase gene gene74 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00370 BCI_RS00375 BCI_0075 BCI_RS00375 89439 91436 - transketolase catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate%3B can transfer ketol groups between several groups%3B in Escherichia coli there are two tkt genes%2C tktA expressed during exponential growth and the tktB during stationary phase gene gene75 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00375 BCI_RS00380 BCI_0076 BCI_RS00380 91457 92410 - transaldolase gene gene76 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00380 BCI_RS00385 BCI_0077 BCI_RS00385 92901 93731 + sulfate/thiosulfate transporter subunit gene gene77 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00385 BCI_RS00390 BCI_0078 cysW cysW 93734 94582 + sulfate/thiosulfate transporter permease subunit Part of the ABC transporter complex cysAWTP involved in sulfate/thiosulfate import gene gene78 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00390 BCI_RS00395 BCI_0079 BCI_RS00395 94585 95646 + sulfate/thiosulfate transporter subunit gene gene79 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00395 BCI_RS00400 BCI_0080 BCI_RS00400 95991 96179 + ferredoxin II%2C 4Fe-4S type gene gene80 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00400 BCI_RS00405 BCI_0081 BCI_RS00405 96281 97555 - tyrosyl-tRNA synthetase gene gene81 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00405 BCI_RS00410 BCI_0082 BCI_RS00410 97591 98241 - pyridoxine/pyridoxamine 5'-phosphate oxidase catalyzes the formation of pyridoxal 5'-phosphate from pyridoxamine 5'-phosphate gene gene82 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00410 BCI_RS00415 BCI_0083 BCI_RS00415 98475 98909 - MarR family transcriptional regulator Transcription regulator that can both activate or repress expression gene gene83 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00415 BCI_RS00420 BCI_0085 BCI_RS00420 99313 99969 + ribonuclease T Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A) gene gene84 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00420 BCI_RS00425 BCI_0086 BCI_RS00425 100009 100368 - glutaredoxin gene gene85 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00425 BCI_RS00430 BCI_0087 BCI_RS00430 100574 101197 - riboflavin synthase subunit alpha catalyzes the formation of riboflavin from 6%2C7-dimethyl-8-(1-D-ribityl)lumazine gene gene86 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00430 BCI_RS00435 BCI_0088 BCI_RS00435 101349 101425 + tRNA-Val tRNA gene87 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00435 BCI_RS00445 BCI_0090 BCI_RS00445 102094 102165 - tRNA-Gln tRNA gene89 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00445 BCI_RS00450 BCI_0091 BCI_RS00450 102178 102254 - tRNA-Met tRNA gene90 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00450 BCI_RS00455 BCI_0092 BCI_RS00455 102263 102336 - tRNA-Gln tRNA gene91 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00455 BCI_RS00460 BCI_0093 BCI_RS00460 102388 102473 - tRNA-Leu tRNA gene92 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00460 BCI_RS00465 BCI_0094 BCI_RS00465 102611 104287 + glutamine--tRNA ligase gene gene93 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00465 BCI_RS00470 BCI_0095 BCI_RS00470 104379 104909 - flavodoxin An electron-transfer protein%3B flavodoxin binds one FMN molecule%2C which serves as a redox-active prosthetic group gene gene94 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00470 BCI_RS00475 BCI_0096 BCI_RS00475 105072 105818 + Nif3-like dinuclear metal center hexameric protein gene gene95 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00475 BCI_RS00480 BCI_0097 sucC sucC 106173 107354 + succinyl-CoA ligase subunit beta catalyzes the interconversion of succinyl-CoA and succinate gene gene96 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00480 BCI_RS00485 BCI_0098 BCI_RS00485 107342 108226 + succinyl-CoA synthetase subunit alpha Catalyzes the only substrate-level phosphorylation in the TCA cycle gene gene97 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00485 BCI_RS00490 BCI_RS00490 tolB tolB 109297 110597 + translocation protein TolB forms dimers%3B may be involved in cell envelope integrity%3B interacts with outer membrane proteins and with the C-terminal domain of inner membrane protein TolA gene gene98 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00490 BCI_RS00495 BCI_RS00495 BCI_RS00495 110956 111273 + peptidoglycan-associated outer membrane lipoprotein gene gene99 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00495 BCI_RS00500 BCI_0101 BCI_RS00500 111372 111935 + hypothetical protein gene gene100 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00500 BCI_RS00505 BCI_0102 BCI_RS00505 111993 113039 + quinolinate synthetase 3 different subfamilies%3B catalyzes the formation of quinolinate from iminoaspartate and dihydroxyacetone phosphate gene gene101 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00505 BCI_RS00510 BCI_0103 BCI_RS00510 112996 114456 - tRNA(Ile)-lysidine synthetase gene gene102 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00510 BCI_RS00515 BCI_0104 BCI_RS00515 114465 116123 - sodium:proton antiporter gene gene103 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00515 BCI_RS00520 BCI_0105 BCI_RS00520 116503 117315 - iron ABC transporter gene gene104 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00520 BCI_RS00525 BCI_RS00525 BCI_RS00525 117359 118096 - ABC transporter gene gene105 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00525 BCI_RS00530 BCI_0107 BCI_RS00530 118286 118783 - single-stranded DNA-binding protein gene gene106 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00530 BCI_RS00535 BCI_RS00535 BCI_RS00535 119469 120775 + glutamate:protein symporter gene gene107 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00535 BCI_RS00540 BCI_0109 BCI_RS00540 121415 121840 + MarR family transcriptional regulator gene gene108 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00540 BCI_RS00545 BCI_0110 BCI_RS00545 122087 122701 + guanylate kinase gene gene109 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00545 BCI_RS00550 BCI_0111 BCI_RS00550 122774 122971 + DNA-directed RNA polymerase subunit omega gene gene110 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00550 BCI_RS00555 BCI_0112 BCI_RS00555 123268 125367 + ATP-dependent DNA helicase RecG catalyzes branch migration in Holliday junction intermediates gene gene111 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00555 BCI_RS00560 BCI_0113 BCI_RS00560 125428 126033 + GTP-binding protein gene gene112 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00560 BCI_RS00565 BCI_0114 BCI_RS00565 126348 127268 - DNA polymerase I gene gene113 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00565 BCI_RS00570 BCI_0115 BCI_RS00570 127464 128618 + DNA polymerase III subunit gamma/tau gene gene114 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00570 BCI_RS00575 BCI_0116 BCI_RS00575 128893 129231 + nucleoid-associated protein gene gene115 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00575 BCI_RS00580 BCI_0117 BCI_RS00580 129409 131304 + chaperone protein HtpG molecular chaperone gene gene116 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00580 BCI_RS00585 BCI_0118 adk adk 131401 132042 + adenylate kinase essential enzyme that recycles AMP in active cells%3B converts ATP and AMP to two molecules of ADP gene gene117 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00585 BCI_RS00590 BCI_0119 BCI_RS00590 132045 133118 - phosphoribosylaminoimidazole carboxylase gene gene118 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00590 BCI_RS00595 BCI_0120 purE purE 133115 133624 - N5-carboxyaminoimidazole ribonucleotide mutase catalyzes the formation of 4-carboxy-5-aminoimidazole ribonucleotide from N5-carboxyaminoimidazole ribonucleotide gene gene119 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00595 BCI_RS00600 BCI_0121 cysS cysS 134028 135416 + cysteine--tRNA ligase catalyzes a two-step reaction%3B charges a cysteine by linking its carboxyl group to the alpha-phosphate of ATP then transfers the aminoacyl-adenylate to its tRNA gene gene120 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00600 BCI_RS00605 BCI_0122 BCI_RS00605 135430 136287 - bifunctional protein FolD gene gene121 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00605 BCI_RS00610 BCI_0123 BCI_RS00610 136485 136562 + tRNA-Arg tRNA gene122 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00610 BCI_RS00620 BCI_0125 dapF dapF 137966 138790 + diaminopimelate epimerase involved in lysine biosynthesis%3B DAP epimerase%3B produces DL-diaminopimelate from LL-diaminopimelate gene gene125 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00620 BCI_RS00625 BCI_0126 BCI_RS00625 138903 139619 + flavin mononucleotide phosphatase YigB%3B member of the haloacid dehalogenase (HAD)-like hydrolases superfamily of protein%3B unknown function gene gene126 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00625 BCI_RS00630 BCI_0127 uvrD uvrD 139674 141614 + DNA helicase II unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand and initiates unwinding most effectively when a single-stranded region is present%3B involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair. gene gene127 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00630 BCI_RS00635 BCI_0128 BCI_RS00635 142061 143011 + magnesium/nickel/cobalt transporter CorA responsible for the influx of magnesium ions gene gene128 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00635 BCI_RS00640 BCI_0130 BCI_RS00640 143136 144143 + membrane protein gene gene129 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00640 BCI_RS00645 BCI_0131 gyrB gyrB 144158 146566 - DNA gyrase subunit B negatively supercoils closed circular double-stranded DNA gene gene130 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00645 BCI_RS00650 BCI_0132 BCI_RS00650 146724 147836 - DNA polymerase III subunit beta binds the polymerase to DNA and acts as a sliding clamp gene gene131 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00650 BCI_RS00655 BCI_0133 rpmH rpmH 148605 148748 + 50S ribosomal protein L34 in Escherichia coli transcription of this gene is enhanced by polyamines gene gene132 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00655 BCI_RS00660 BCI_0134 rnpA rnpA 148760 149107 + ribonuclease P protein component protein component of RNaseP which catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'terminus%3B this enzyme also cleaves other RNA substrates gene gene133 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00660 BCI_RS00665 BCI_0135 BCI_RS00665 149083 149340 + membrane protein insertion efficiency factor YidD gene gene134 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00665 BCI_RS00670 BCI_0136 BCI_RS00670 149343 150944 + insertase functions to insert inner membrane proteins into the IM in Escherichia coli%3B interacts with transmembrane segments%3B functions in both Sec-dependent and -independent membrane insertion%3B similar to Oxa1p in mitochondria gene gene135 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00670 BCI_RS00675 BCI_0137 trmE trmE 150941 152314 + tRNA modification GTPase MnmE in Escherichia coli this protein is involved in the biosynthesis of the hypermodified nucleoside 5-methylaminomethyl-2-thiouridine%2C which is found in the wobble position of some tRNAs and affects ribosomal frameshifting%3B shows potassium-dependent dimerization and GTP hydrolysis%3B also involved in regulation of glutamate-dependent acid resistance and activation of gadE gene gene136 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00675 BCI_RS00680 BCI_0138 BCI_RS00680 152320 154158 - glucosamine--fructose-6-phosphate aminotransferase Catalyzes the first step in hexosamine metabolism%2C converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source gene gene137 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00680 BCI_RS00685 BCI_0139 glmU glmU 154201 155610 - bifunctional protein GlmU forms a homotrimer%3B catalyzes the acetylation of glucosamine-1-phosphate and uridylation of N-acetylglucosamine-1-phosphate to produce UDP-GlcNAc%3B function in cell wall synthesis gene gene138 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00685 BCI_RS00690 BCI_0140 atpC atpC 155664 156086 - ATP synthase epsilon chain part of catalytic core of ATP synthase%3B alpha(3)beta(3)gamma(1)delta(1)epsilon(1)%3B involved in producing ATP from ADP in the presence of the proton motive force across the membrane gene gene139 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00690 BCI_RS00695 BCI_0141 BCI_RS00695 156100 157473 - ATP synthase subunit beta gene gene140 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00695 BCI_RS00700 BCI_0142 BCI_RS00700 157519 158382 - ATP synthase subunit gamma Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is a regulatory subunit gene gene141 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00700 BCI_RS00705 BCI_0143 BCI_RS00705 158429 159970 - ATP synthase subunit alpha produces ATP from ADP in the presence of a proton gradient across the membrane%3B the alpha chain is a catalytic subunit gene gene142 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00705 BCI_RS00710 BCI_0144 BCI_RS00710 159992 160525 - ATP synthase subunit delta Produces ATP from ADP in the presence of a proton gradient across the membrane%3B the delta subunit is part of the catalytic core of the ATP synthase complex gene gene143 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00710 BCI_RS00715 BCI_0145 BCI_RS00715 160548 161018 - ATP synthase subunit b gene gene144 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00715 BCI_RS00720 BCI_0146 BCI_RS00720 161047 161289 - ATP synthase subunit c Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit C is part of the membrane proton channel F0 gene gene145 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00720 BCI_RS00725 BCI_0147 BCI_RS00725 161326 162147 - ATP synthase subunit a Produces ATP from ADP in the presence of a proton gradient across the membrane. Subunit A is part of the membrane proton channel F0 gene gene146 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00725 BCI_RS00730 BCI_0148 BCI_RS00730 162235 164130 - tRNA uridine 5-carboxymethylaminomethyl modification enzyme MnmG gene gene147 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00730 BCI_RS00735 BCI_0149 ygfZ ygfZ 164177 165154 - tRNA-modifying protein YgfZ physiological role is not clear%3B not essential for growth but mutants grow poorly%3B mutations suppress hda null mutations%3B may be involved in regulation of ATP-DnaA levels%3B may also be involved in regulation of tRNA modifications%3B can bind folic acid and tetrahydrofolate%3B forms a three domain ring-like structure with a central channel%3B structurally similar to DMGO protein from A. globiformis%3B shows sequence similarity to yeast CAF17 transcriptional regulato%3B Hda supressor gene gene148 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00735 BCI_RS00740 BCI_0150 BCI_RS00740 165307 167034 + ssDNA exonuclease RecJ 5'-3' single-stranded-DNA-specific exonuclease gene gene149 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00740 BCI_RS00745 BCI_RS00745 BCI_RS00745 167153 168076 + peptide chain release factor 2 catalyzes the release of newly synthesized polypeptide chains at the stop codons UAA and UGA gene gene150 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00745 BCI_RS00750 BCI_0152 lysS lysS 168085 169605 + lysyl-tRNA synthetase class II%3B LysRS2%3B catalyzes a two-step reaction%2C first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B in Methanosarcina barkeri%2C LysRS2 charges both tRNA molecules for lysine that exist in this organism and in addition can charge the tRNAPyl with lysine in the presence of LysRS1 gene gene151 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00750 BCI_RS00755 BCI_0153 BCI_RS00755 169659 170483 + glutamate racemase converts L-glutamate to D-glutamate%2C a component of peptidoglycan gene gene152 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00755 BCI_RS00760 BCI_0509 BCI_RS00760 170746 172311 + 16S ribosomal RNA rRNA gene153 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00760 BCI_RS00765 BCI_0508 BCI_RS00765 172415 172487 + tRNA-Glu tRNA gene154 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00765 BCI_RS00770 BCI_0507 BCI_RS00770 172562 175485 + 23S ribosomal RNA rRNA gene155 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00770 BCI_RS00775 BCI_0506 BCI_RS00775 175508 175622 + 5S ribosomal RNA rRNA gene156 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00775 BCI_RS00780 BCI_0158 BCI_RS00780 175644 175720 + tRNA-Asp tRNA gene157 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00780 BCI_RS00785 BCI_0159 BCI_RS00785 175744 175820 + tRNA-Trp tRNA gene158 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00785 BCI_RS00790 BCI_0160 glyS glyS 175857 177956 - glycine--tRNA ligase subunit beta glycine--tRNA ligase beta chain%3B glyS%3B class II aminoacyl tRNA synthetase%3B tetramer of alpha(2)beta(2)%3B catalyzes a two-step reaction%3B first charging a glycine molecule by linking the carboxyl group to the alpha-phosphate of ATP%3B second by transfer of the aminoacyl-adenylate to its tRNA gene gene159 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00790 BCI_RS00795 BCI_0161 BCI_RS00795 177962 178870 - glycine--tRNA ligase subunit alpha gene gene160 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00795 BCI_RS00800 BCI_0162 metF metF 179601 180509 - 5%2C10-methylenetetrahydrofolate reductase MTHFR%3B catalyzes NADH-linked reduction of 5%2C10-methylenetetrahydrofolate to 5-methyltetrahydrofolate using FAD as a cofactor gene gene161 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00800 BCI_RS00805 BCI_0163 BCI_RS00805 180690 181853 - cystathionine gamma-synthase catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine gene gene162 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00805 BCI_RS00810 BCI_0165 BCI_RS00810 182488 182715 - 50S ribosomal protein L31 gene gene163 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00810 BCI_RS00815 BCI_0166 BCI_RS00815 182886 185000 + primosome assembly protein PriA binding of PriA to forked DNA starts the assembly of the primosome%2C also possesses 3'-5' helicase activity gene gene164 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00815 BCI_RS00820 BCI_0167 BCI_RS00820 185225 185767 + ATP-dependent protease subunit HslV heat shock protein involved in degradation of misfolded proteins gene gene165 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00820 BCI_RS00825 BCI_0168 hslU hslU 185771 187111 + ATP-dependent protease ATPase subunit HslU heat shock protein involved in degradation of misfolded proteins gene gene166 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00825 BCI_RS00830 BCI_0169 BCI_RS00830 187374 188144 + triosephosphate isomerase Reversibly isomerizes the ketone sugar dihydroxyacetone phosphate to the aldehyde sugar glyceraldehyde-3-phosphate gene gene167 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00830 BCI_RS00835 BCI_0170 BCI_RS00835 188146 189135 - sulfate transporter subunit gene gene168 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00835 BCI_RS00840 BCI_0171 BCI_RS00840 189206 190168 - ATP-dependent 6-phosphofructokinase catalyzes the formation of D-fructose 1%2C6-bisphosphate from D-fructose 6-phosphate in glycolysis gene gene169 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00840 BCI_RS00845 BCI_0172 cysE cysE 190415 191230 - serine acetyltransferase catalyzes the O-acetylation of serine gene gene170 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00845 BCI_RS00850 BCI_0173 BCI_RS00850 191281 192303 - glycerol-3-phosphate dehydrogenase [NAD(P)+] gene gene171 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00850 BCI_RS00855 BCI_RS00855 BCI_RS00855 192398 192655 - glutaredoxin gene gene172 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00855 BCI_RS00860 BCI_0174 BCI_RS00860 192689 193120 - hypothetical protein gene gene173 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00860 BCI_RS00865 BCI_0175 BCI_RS00865 193227 194444 + M23 family peptidase gene gene174 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00865 BCI_RS00870 BCI_0176 coaD coaD 194725 195207 + phosphopantetheine adenylyltransferase Catalyzes the conversion of ATP and pantetheine 4'-phosphate to diphosphate and 3'-dephospho-coA gene gene175 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00870 BCI_RS00875 BCI_0177 BCI_RS00875 195204 196013 - formamidopyrimidine-DNA glycosylase Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases gene gene176 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00875 BCI_RS00880 BCI_0178 rpmG rpmG 196074 196241 - 50S ribosomal protein L33 in Escherichia coli BM108%2C a mutation that results in lack of L33 synthesis had no effect on ribosome synthesis or function%3B there are paralogous genes in several bacterial genomes%2C and a CXXC motif for zinc binding and an upstream regulation region of the paralog lacking this motif that are regulated by zinc similar to other ribosomal proteins like L31%3B the proteins in this group lack the CXXC motif gene gene177 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00880 BCI_RS00885 BCI_0179 BCI_RS00885 196291 196518 - 50S ribosomal protein L28 gene gene178 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00885 BCI_RS00890 BCI_0180 BCI_RS00890 196617 197483 - hypothetical protein gene gene179 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00890 BCI_RS00895 BCI_0181 pyrE pyrE 197581 198222 + orotate phosphoribosyltransferase involved in fifth step of pyrimidine biosynthesis%3B converts orotidine 5'-phosphate and diphosphate to orotate and 5-phospho-alpha-D-ribose 1-diphosphate gene gene180 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00895 BCI_RS00900 BCI_0182 BCI_RS00900 198277 198732 - deoxyuridine 5'-triphosphate nucleotidohydrolase catalyzes the formation of dUMP from dUTP gene gene181 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00900 BCI_RS00905 BCI_0183 BCI_RS00905 198710 199924 - phosphopantothenoylcysteine decarboxylase catalyzes the conjugation of cysteine to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine%2C which is then decarboxylated to form 4'-phosphopantotheine gene gene182 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00905 BCI_RS00910 BCI_0184 BCI_RS00910 200132 200208 - tRNA-Pro tRNA gene183 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00910 BCI_RS00915 BCI_0185 BCI_RS00915 200299 200387 - tRNA-Leu tRNA gene184 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00915 BCI_RS00920 BCI_0186 BCI_RS00920 200410 200485 - tRNA-His tRNA gene185 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00920 BCI_RS00925 BCI_0187 BCI_RS00925 200503 200580 - tRNA-Arg tRNA gene186 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00925 BCI_RS00930 BCI_0188 rho rho 200830 202089 - transcription termination factor Rho An RNA-DNA helicase that actively releases nascent mRNAs from paused transcription complexes gene gene187 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00930 BCI_RS00935 BCI_0189 trxA trxA 202183 202509 - thioredoxin gene gene188 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00935 BCI_RS00940 BCI_0190 BCI_RS00940 202633 202971 - hypothetical protein gene gene189 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00940 BCI_RS00945 BCI_0191 BCI_RS00945 203304 204299 + phospho-2-dehydro-3-deoxyheptonate aldolase catalyzes the formation of 3-deoxy-D-arabino-hept-2-ulosonate 7 phosphate from phosphoenolpyruvate and D-erythrose 4-phosphate%2C tyrosine sensitive gene gene190 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00945 BCI_RS00950 BCI_0192 BCI_RS00950 204398 205093 - outer membrane biogenesis protein BamD gene gene191 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00950 BCI_RS00955 BCI_0193 rluD rluD 205192 206151 + ribosomal large subunit pseudouridine synthase D responsible for synthesis of pseudouridine from uracil at positions 1911%2C 1915 and 1917 in 23S ribosomal RNA gene gene192 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00955 BCI_RS00960 BCI_0194 BCI_RS00960 206290 208878 + chaperone protein ClpB gene gene193 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00960 BCI_RS00965 BCI_0195 BCI_RS00965 208875 209222 - 50S ribosomal protein L19 gene gene194 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00965 BCI_RS00970 BCI_0196 trmD trmD 209239 209997 - tRNA (guanine-N(1)-)-methyltransferase methylates guanosine-37 in various tRNAs%3B uses S-adenosyl-L-methionine to transfer methyl group to tRNA gene gene195 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00970 BCI_RS00975 BCI_0197 rimM rimM 210022 210591 - 16S rRNA-processing protein RimM Essential for efficient processing of 16S rRNA gene gene196 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00975 BCI_RS00980 BCI_0198 BCI_RS00980 210539 210805 - 30S ribosomal protein S16 gene gene197 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00980 BCI_RS00985 BCI_0199 BCI_RS00985 210902 212251 - signal recognition particle protein gene gene198 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00985 BCI_RS00990 BCI_0201 BCI_RS00990 212553 214124 - glutamate--cysteine ligase involved in the first step of glutathione biosynthesis gene gene199 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00990 BCI_RS00995 BCI_0202 BCI_RS00995 214296 214372 - tRNA-Arg tRNA gene200 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS00995 BCI_RS01000 BCI_0203 BCI_RS01000 214380 214472 - tRNA-Ser tRNA gene201 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01000 BCI_RS01005 BCI_0204 BCI_RS01005 214670 214855 - carbon storage regulator homolog affects carbohydrate metabolism%3B has regulatory role in many processes gene gene202 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01005 BCI_RS01010 BCI_0205 BCI_RS01010 215037 217691 - alanine--tRNA ligase gene gene203 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01010 BCI_RS01015 BCI_0206 recA recA 217939 218991 - protein RecA catalyzes the hydrolysis of ATP in the presence of single-stranded DNA%2C the ATP-dependent uptake of single-stranded DNA by duplex DNA%2C and the ATP-dependent hybridization of homologous single-stranded DNAs gene gene204 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01015 BCI_RS01020 BCI_0207 BCI_RS01020 219478 220260 + amino acid ABC transporter substrate-binding protein gene gene205 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01020 BCI_RS01025 BCI_0208 BCI_RS01025 220287 220943 + cysteine ABC transporter permease gene gene206 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01025 BCI_RS01030 BCI_0209 BCI_RS01030 221030 223597 + DNA mismatch repair protein MutS This protein performs the mismatch recognition step during the DNA repair process gene gene207 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01030 BCI_RS01035 BCI_0210 ispF ispF 223856 224332 - 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate synthase catalyzes the conversion of 4-diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate into 2-C-methyl-D-erythritol 2%2C4-cyclodiphosphate gene gene208 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01035 BCI_RS01040 BCI_0211 BCI_RS01040 224342 225067 - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase gene gene209 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01040 BCI_RS01045 BCI_0212 BCI_RS01045 225382 226005 - adenylylsulfate kinase converts ATP and adenylyl sulfate to ADP and 3'-phosphoadenylyl sulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis gene gene210 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01045 BCI_RS01050 BCI_0213 cysN cysN 226002 227444 - sulfate adenylyltransferase subunit 1 may be GTPase that regulates ATP sulfurylase activity that is involved in converting ATP and sulfate to diphosphate and adenylylsulfate%3B in Escherichia coli this enzyme functions in cysteine biosynthesis in the first step%3B forms a heterodimer with CysD%3B part of the GTP-binding elongation factor family CysN/NodQ gene gene211 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01050 BCI_RS01055 BCI_0214 BCI_RS01055 227457 228365 - sulfate adenylyltransferase subunit 2 with CysN catalyzes the formation of adenylylsulfate from sulfate and ATP gene gene212 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01055 BCI_RS01060 BCI_0215 BCI_RS01060 228409 229797 - siroheme synthase gene gene213 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01060 BCI_RS01065 BCI_0216 BCI_RS01065 229965 230702 - phosphoadenosine phosphosulfate reductase catalyzes the reduction of 3'-phosphoadenylyl sulfate into sulfite gene gene214 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01065 BCI_RS01070 BCI_0217 BCI_RS01070 230716 232416 - sulfite reductase subunit beta hemoprotein%3B NADPH dependent%3B with the alpha subunit (a flavoprotein) catalyzes the reduction of sulfite to sulfide gene gene215 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01070 BCI_RS01075 BCI_0218 cysJ cysJ 232416 234203 - sulfite reductase subunit alpha catalyzes the reduction of sulfite to sulfide in the biosynthesis of L-cysteine from sulfate%3B a flavoprotein with flavin reductase activity gene gene216 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01075 BCI_RS01080 BCI_0219 BCI_RS01080 234535 234894 + 6-carboxy-5%2C6%2C7%2C8-tetrahydropterin synthase gene gene217 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01080 BCI_RS01085 BCI_0220 BCI_RS01085 234917 235588 - 7-cyano-7-deazaguanosine (preQ0) biosynthesis protein QueE gene gene218 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01085 BCI_RS01090 BCI_0221 eno eno 235629 236930 - enolase catalyzes the formation of phosphoenolpyruvate from 2-phospho-D-glycerate in glycolysis gene gene219 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01090 BCI_RS01095 BCI_0222 pyrG pyrG 236998 238629 - CTP synthase CTP synthase%3B cytidine triphosphate synthetase%3B catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen%3B in Escherichia coli this enzyme forms a homotetramer gene gene220 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01095 BCI_RS01100 BCI_RS01100 BCI_RS01100 238738 239418 - hypothetical protein gene gene221 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01100 BCI_RS01105 BCI_0224 BCI_RS01105 239976 240665 + 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase enables the cleavage of the glycosidic bond in both 5'-methylthioadenosine and S-adenosylhomocysteine gene gene222 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01105 BCI_RS01110 BCI_0225 BCI_RS01110 240709 241056 - iron-sulfur cluster insertion protein ErpA essential respiratory protein A%3B may be involved in the transfer of iron-sulfur clusters%3B essential for growth using oxygen or alternate electron acceptors gene gene223 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01110 BCI_RS01115 BCI_0227 dksA dksA 242468 242923 + transcriptional regulator gene gene224 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01115 BCI_RS01120 BCI_RS01120 pcnB pcnB 243250 244482 + poly(A) polymerase I Polymerase that creates the 3' poly(A) tail found in some mRNA's gene gene225 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01120 BCI_RS01125 BCI_0229 BCI_RS01125 244508 245011 + 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase gene gene226 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01125 BCI_RS01130 BCI_0230 panB panB 245068 245865 + 3-methyl-2-oxobutanoate hydroxymethyltransferase catalyzes the formation of tetrahydrofolate and 2-dehydropantoate from 5%2C10-methylenetetrahydrofolate and 3-methyl-2-oxobutanoate gene gene227 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01130 BCI_RS01135 BCI_0231 panC panC 245884 246741 + pantothenate synthetase catalyzes the formation of (R)-pantothenate from pantoate and beta-alanine gene gene228 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01135 BCI_RS01140 BCI_0232 leuS leuS 246940 249525 + leucine--tRNA ligase leucine--tRNA ligase%3B LeuRS%3B class-I aminoacyl-tRNA synthetase%3B charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA%3B due to the large number of codons that tRNA(Leu) recognizes%2C the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA%2C but instead recognition is dependent on a conserved discriminator base A37 and a long arm%3B an editing domain hydrolyzes misformed products%3B in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase gene gene229 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01140 BCI_RS01145 BCI_0233 holA holA 249742 250779 + DNA polymerase III subunit delta required for the assembly and function of the DNAX complex which is required for the assembly of the beta subunit onto primed DNA gene gene230 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01145 BCI_RS01150 BCI_0234 BCI_RS01150 250772 251425 + nicotinate-nucleotide adenylyltransferase gene gene231 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01150 BCI_RS01155 BCI_0235 BCI_RS01155 251496 253361 + penicillin-binding protein 2 gene gene232 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01155 BCI_RS01160 BCI_0236 BCI_RS01160 253354 254466 + cell wall shape-determining protein gene gene233 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01160 BCI_RS01165 BCI_0237 BCI_RS01165 254594 255277 + octanoyltransferase lipoyl/octanoyltransferase%3B catalyzes the transfer of the lipoyl/octanoyl moiety of lipoyl/octanoyl-ACP onto lipoate-dependent enzymes like pyruvate dehydrogenase and the glycine cleavage system H protein gene gene234 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01165 BCI_RS01170 BCI_0238 BCI_RS01170 255313 256197 + lipoyl synthase catalyzes the radical-mediated insertion of two sulfur atoms into an acyl carrier protein (ACP) bound to an octanoyl group to produce a lipoyl group gene gene235 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01170 BCI_RS01175 BCI_0239 BCI_RS01175 256427 257662 + multidrug resistance protein MdtH Confers resistance to norfloxacin and enoxacin gene gene236 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01175 BCI_RS01180 BCI_0240 BCI_RS01180 257862 258425 + CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase gene gene237 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01180 BCI_RS01185 BCI_0241 BCI_RS01185 258467 258541 + tRNA-Gly tRNA gene238 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01185 BCI_RS01190 BCI_0242 BCI_RS01190 258685 258755 + tRNA-Cys tRNA gene239 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01190 BCI_RS01195 BCI_0243 BCI_RS01195 258769 258854 + tRNA-Leu tRNA gene240 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01195 BCI_RS01200 BCI_0244 BCI_RS01200 258950 259951 + 6-phosphogluconolactonase catalyzes the hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate gene gene241 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01200 BCI_RS01205 BCI_0245 BCI_RS01205 259963 261264 - adenosylmethionine--8-amino-7-oxononanoate aminotransferase BioA catalyzes the formation of S-adenosyl-4-methylthionine-2-oxobutanoate and 7%2C8-diaminononanoate from S-adenosyl-L-methionine and 8-amino-7-oxononanoate gene gene242 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01205 BCI_RS01210 BCI_0246 BCI_RS01210 261372 262400 + biotin synthase catalyzes the formation of biotin from dethiobiotin gene gene243 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01210 BCI_RS01215 BCI_0247 BCI_RS01215 262397 263575 + 8-amino-7-oxononanoate synthase catalyzes the formation of 8-amino-7-oxononanoate from 6-carboxyhexanoyl-CoA and L-alanine gene gene244 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01215 BCI_RS01220 BCI_0248 BCI_RS01220 263562 264323 + malonyl-[acyl-carrier protein] O-methyltransferase BioC gene gene245 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01220 BCI_RS01225 BCI_0249 bioD bioD 264316 264993 + ATP-dependent dethiobiotin synthetase BioD DTB synthetase%3B dethiobiotin synthase%3B involved in production of dethiobiotin from ATP and 7%2C8-diaminononanoate and carbon dioxide%3B contains magnesium gene gene246 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01225 BCI_RS01230 BCI_0250 BCI_RS01230 265457 266218 + amino acid ABC transporter ATP-binding protein gene gene247 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01230 BCI_RS01235 BCI_0251 gpmA gpmA 266278 266991 + 2%2C3-bisphosphoglycerate-dependent phosphoglycerate mutase 2%2C3-bisphosphoglycerate-dependent%3B catalyzes the interconversion of 2-phosphoglycerate to 3-phosphoglycerate gene gene248 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01235 BCI_RS01240 BCI_0252 BCI_RS01240 266998 268089 + phosphoserine aminotransferase catalyzes the formation of 3-phosphonooxypyruvate and glutamate from O-phospho-L-serine and 2-oxoglutarate%3B catalyzes 4 phosphohydroxy L-threonine from 2-oxo 3 hydroxy 4- phosphobutanoate%3B required both in major phosphorylated pathway of serine biosynthesis and in the biosynthesis of pyridoxine gene gene249 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01240 BCI_RS01245 BCI_0253 BCI_RS01245 268184 269470 + 3-phosphoshikimate 1-carboxyvinyltransferase gene gene250 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01245 BCI_RS01250 BCI_0254 BCI_RS01250 269532 270209 + cytidylate kinase gene gene251 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01250 BCI_RS01255 BCI_0255 rpsA rpsA 270342 272018 + 30S ribosomal protein S1 in Escherichia coli this protein is involved in binding to the leader sequence of mRNAs and is itself bound to the 30S subunit%3B autoregulates expression via a C-terminal domain%3B in most gram negative organisms this protein is composed of 6 repeats of the S1 domain while in gram positive there are 4 repeats%3B the S1 nucleic acid-binding domain is found associated with other proteins gene gene252 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01255 BCI_RS01260 BCI_0257 BCI_RS01260 272440 273084 - protein disulfide isomerase gene gene253 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01260 BCI_RS01265 BCI_0258 BCI_RS01265 273549 274484 + aspartate carbamoyltransferase gene gene254 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01265 BCI_RS01270 BCI_0259 BCI_RS01270 274498 274968 + aspartate carbamoyltransferase regulatory chain involved in the allosteric regulation of aspartate carbamoyltransferase gene gene255 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01270 BCI_RS01275 BCI_0260 BCI_RS01275 275014 275409 + reactive intermediate/imine deaminase has endoribonuclease activity on mRNA gene gene256 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01275 BCI_RS01280 BCI_0261 BCI_RS01280 275505 275714 - cold-shock protein CspE gene gene257 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01280 BCI_RS01285 BCI_0262 BCI_RS01285 276020 276718 + 7-cyano-7-deazaguanine synthase YbaX%3B catalyzes the transformation of GTP to 7-cyano-7-deazaguanine (preQ0)%2C as one of the early reactions of quenosine biosynthesis%3B quenosine is a modified nucleoside that occurs at the wobble position of GUN anticodons in tRNAs for Asn%2C Asp%2C Tyr%2C and His gene gene258 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01285 BCI_RS01290 BCI_0263 BCI_RS01290 276746 279100 - peptidase gene gene259 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01290 BCI_RS01295 BCI_0264 clpX clpX 279309 280574 - ATP-dependent Clp protease ATP-binding subunit ClpX binds and unfolds substrates as part of the ClpXP protease gene gene260 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01295 BCI_RS01300 BCI_0265 BCI_RS01300 280711 281328 - ATP-dependent Clp protease proteolytic subunit gene gene261 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01300 BCI_RS01305 BCI_0266 BCI_RS01305 281550 282812 - hypothetical protein gene gene262 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01305 BCI_RS01310 BCI_0267 BCI_RS01310 283346 284260 + cytochrome O ubiquinol oxidase gene gene263 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01310 BCI_RS01315 BCI_0268 BCI_RS01315 284291 286288 + cytochrome O ubiquinol oxidase gene gene264 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01315 BCI_RS01320 BCI_0269 BCI_RS01320 286275 286886 + cytochrome O ubiquinol oxidase gene gene265 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01320 BCI_RS01325 BCI_RS01325 BCI_RS01325 286891 287238 + hypothetical protein gene gene266 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01325 BCI_RS01330 BCI_0270 BCI_RS01330 287238 288104 + protoheme IX farnesyltransferase converts protoheme IX and farnesyl diphosphate to heme O gene gene267 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01330 BCI_RS01335 BCI_0271 BCI_RS01335 288133 289542 + membrane protein gene gene268 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01335 BCI_RS01340 BCI_0272 BCI_RS01340 289559 290440 + 2-dehydropantoate 2-reductase ketopantoate reductase%3B catalyzes the NADPH reduction of ketopantoate to pantoate%3B functions in pantothenate (vitamin B5) biosynthesis gene gene269 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01340 BCI_RS01345 BCI_0273 BCI_RS01345 290454 290750 - thiamine biosynthesis protein ThiI gene gene270 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01345 BCI_RS01350 BCI_0274 BCI_RS01350 291155 292048 + geranyl transferase gene gene271 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01350 BCI_RS01355 BCI_0275 BCI_RS01355 292087 293958 + 1-deoxy-D-xylulose-5-phosphate synthase catalyzes the formation of 1-deoxy-D-xylulose 5-phosphate from pyruvate and D-glyceraldehyde 3-phosphate gene gene272 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01355 BCI_RS01360 BCI_0276 BCI_RS01360 294028 295764 + arginine--tRNA ligase gene gene273 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01360 BCI_RS01365 BCI_0277 BCI_RS01365 295815 297341 - membrane protein gene gene274 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01365 BCI_RS01370 BCI_0278 BCI_RS01370 297338 297778 - holo-ACP synthase gene gene275 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01370 BCI_RS01375 BCI_0279 BCI_RS01375 297778 298509 - pyridoxine 5'-phosphate synthase involved in the de novo synthesis of pyridoxine (Vitamin B6) gene gene276 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01375 BCI_RS01380 BCI_0280 BCI_RS01380 298643 299548 - GTPase Era gene gene277 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01380 BCI_RS01385 BCI_0281 rnc rnc 299551 300228 - ribonuclease III cytoplasmic enzyme involved in processing rRNA and some mRNAs%3B substrates typically have dsRNA regions%3B forms a homodimer%3B have N-terminal nuclease and C-terminal RNA-binding domains%3B requires magnesium as preferred ion for activity gene gene278 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01385 BCI_RS01390 BCI_0282 BCI_RS01390 300268 301203 - signal peptidase catalyzes the cleavage of the amino-terminal leader peptide from secretory proteins gene gene279 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01390 BCI_RS01395 BCI_0283 BCI_RS01395 301212 303020 - elongation factor 4 gene gene280 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01395 BCI_RS01400 BCI_0284 BCI_RS01400 303208 303283 + tRNA-Thr tRNA gene281 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01400 BCI_RS01405 BCI_0285 BCI_RS01405 303301 306174 - valine--tRNA ligase gene gene282 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01405 BCI_RS01410 BCI_0286 BCI_RS01410 306184 306648 - DNA polymerase III subunit chi binds to single-strand binding (SSB) protein and acts as a bridge between the DnaX clamp loader complex and the SSB gene gene283 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01410 BCI_RS01415 BCI_0287 BCI_RS01415 306672 308174 - cytosol aminopeptidase catalyzes the removal of N-terminal amino acids preferably from various peptides%3B a cyteinylglycinase%2C transcription regulator and site-specific recombination factor gene gene284 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01415 BCI_RS01420 BCI_0288 nadE nadE 308547 309401 + NAD synthetase catalyzes the formation of nicotinamide adenine dinucleotide (NAD) from nicotinic acid adenine dinucleotide (NAAD) using either ammonia or glutamine as the amide donor and ATP%3B ammonia-utilizing enzymes include the ones from Bacillus and Escherichia coli while glutamine-utilizing enzymes include the Mycobacterial one%3B forms homodimers gene gene285 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01420 BCI_RS01425 BCI_0289 BCI_RS01425 309469 310311 - SAM-dependent methyltransferase HemK%3B PrmC%3B transfers a methyl group from S-adenosylmethionine to amide nitrogen of specific glutamine residues in protein chain release factors PrfA and PrfB gene gene286 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01425 BCI_RS01430 BCI_0290 prfA prfA 310311 311411 - peptide chain release factor 1 recognizes the termination signals UAG and UAA during protein translation a specificity which is dependent on amino acid residues residing in loops of the L-shaped tRNA-like molecule of RF1%3B this protein is similar to release factor 2 gene gene287 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01430 BCI_RS01435 BCI_0291 BCI_RS01435 311719 312366 + hypothetical protein gene gene288 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01435 BCI_RS01440 BCI_0292 BCI_RS01440 312363 313238 + 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase gene gene289 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01440 BCI_RS01445 BCI_0293 BCI_RS01445 313291 314229 + ribose-phosphate pyrophosphokinase catalyzes the formation of 5-phospho-alpha-D-ribose 1-phosphate from D-ribose 5-phosphate and ATP gene gene290 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01445 BCI_RS01450 BCI_0294 BCI_RS01450 314339 314920 + peptidyl-tRNA hydrolase Enables the recycling of peptidyl-tRNAs produced at termination of translation gene gene291 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01450 BCI_RS01455 BCI_0295 ychF ychF 314970 316040 + GTP-binding protein EngD%3B translation-associated GTPase%3B the crystal structure of the Haemophilus influenzae YchF protein showed similarity to the yeast structure (PDB: 1NI3)%3B fluorescence spectroscopy revealed nucleic acid binding%3B the yeast protein YBR025c interacts with the translation elongation factor eEF1 gene gene292 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01455 BCI_RS01460 BCI_0296 BCI_RS01460 316118 316906 + enoyl-ACP reductase Catalyzes a key regulatory step in fatty acid biosynthesis gene gene293 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01460 BCI_RS01465 BCI_0297 BCI_RS01465 317059 318996 + exoribonuclease 2 Involved in mRNA degradation. Hydrolyzes single-stranded polyribonucleotides processively in the 3' to 5' direction gene gene294 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01465 BCI_RS01470 BCI_0298 BCI_RS01470 319003 319752 - orotidine 5'-phosphate decarboxylase gene gene295 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01470 BCI_RS01475 BCI_0299 BCI_RS01475 319787 320083 - hypothetical protein gene gene296 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01475 BCI_RS01480 BCI_0300 ribA ribA 320418 321017 + GTP cyclohydrolase-2 catalyzes the conversion of GTP to formate and 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and diphosphate gene gene297 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01480 BCI_RS01485 BCI_0301 cysB cysB 321060 322034 - CysB family transcriptional regulator LysR-type transcriptional regulator%3B contains helix-turn-helix (HTH) motif%3B in Escherichia coli this protein regulates cysteine biosynthesis by controlling expression of the cys regulon%3B autoregulates expression%3B crystal structure of Klebsiella aerogenes showed tetramer formation gene gene298 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01485 BCI_RS01490 BCI_0302 BCI_RS01490 322283 324856 - DNA topoisomerase I catalyzes the ATP-dependent breakage of single-stranded DNA followed by passage and rejoining%2C maintains net negative superhelicity gene gene299 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01490 BCI_RS01495 BCI_0303 BCI_RS01495 325306 326070 + membrane protein gene gene300 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01495 BCI_RS01500 BCI_0304 BCI_RS01500 326265 326567 + hypothetical protein unknown function%3B YciI from Haemophilus influenzae presents crystal structure similarity to a muconolactone isomerase%2C but does not seem to catalyze any of the predicted reactions based on sequence and structure similarity gene gene301 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01500 BCI_RS01505 BCI_0305 cls cls 326732 328180 + cardiolipin synthase catalyzes the transfer of a phosphatidyl group to phosphodidylglycerol to form cardiolipin (diphosphatidylglycerol) gene gene302 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01505 BCI_RS01510 BCI_0306 BCI_RS01510 328635 329045 + DNA-binding protein gene gene303 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01510 BCI_RS01515 BCI_0307 BCI_RS01515 329091 329966 - protease HtpX metalloprotease gene gene304 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01515 BCI_RS01520 BCI_0308 BCI_RS01520 330171 330659 - ferritin cytoplasmic iron storage protein gene gene305 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01520 BCI_RS01525 BCI_0309 BCI_RS01525 330747 332225 - glucose-6-phosphate 1-dehydrogenase catalyzes the formation of D-glucono-1%2C5-lactone 6-phosphate from D-glucose 6-phosphate gene gene306 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01525 BCI_RS01530 BCI_0310 BCI_RS01530 332646 334097 + pyruvate kinase catalyzes the formation of phosphoenolpyruvate from pyruvate gene gene307 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01530 BCI_RS01535 BCI_0311 BCI_RS01535 334517 335866 + manganese transporter gene gene308 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01535 BCI_RS01540 BCI_0312 ruvB ruvB 336040 337047 - Holliday junction DNA helicase RuvB promotes strand exchange during homologous recombination%3B RuvAB complex promotes branch migration%3B RuvABC complex scans the DNA during branch migration and resolves Holliday junctions at consensus sequences%3B forms hexameric rings around opposite DNA arms%3B requires ATP for branch migration and orientation of RuvAB complex determines direction of migration gene gene309 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01540 BCI_RS01545 BCI_0313 BCI_RS01545 337056 337646 - Holliday junction DNA helicase RuvA gene gene310 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01545 BCI_RS01550 BCI_0314 ruvC ruvC 337688 338209 - crossover junction endodeoxyribonuclease RuvC endonuclease%3B resolves Holliday structures%3B forms a complex of RuvABC%3B the junction binding protein RuvA forms a hexameric ring along with the RuvB helicase and catalyzes branch migration%3B RuvC then interacts with RuvAB to resolve the Holliday junction by nicking DNA strands of like polarity gene gene311 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01550 BCI_RS01555 BCI_0315 BCI_RS01555 338703 340472 - aspartate--tRNA ligase gene gene312 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01555 BCI_RS01560 BCI_0316 BCI_RS01560 340697 341431 - phosphatase gene gene313 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01560 BCI_RS01565 BCI_0317 BCI_RS01565 341666 341755 + tRNA-Ser tRNA gene314 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01565 BCI_RS01570 BCI_0318 BCI_RS01570 341775 343067 - serine--tRNA ligase gene gene315 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01570 BCI_RS01575 BCI_0319 BCI_RS01575 343217 343843 - outer membrane lipoprotein carrier protein LolA gene gene316 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01575 BCI_RS01580 BCI_0320 BCI_RS01580 343945 345879 - hypothetical protein gene gene317 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01580 BCI_RS01585 BCI_0321 BCI_RS01585 346139 347098 + thioredoxin reductase catalyzes the transfer of electrons from NADPH to thioredoxin%3B FAD/NAD(P) binding gene gene318 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01585 BCI_RS01590 BCI_0322 BCI_RS01590 347213 347431 + translation initiation factor IF-1 gene gene319 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01590 BCI_RS01595 BCI_0323 BCI_RS01595 347607 348335 + arginine ABC transporter ATP-binding protein gene gene320 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01595 BCI_RS01600 BCI_0324 BCI_RS01600 348356 349084 + arginine ABC transporter substrate-binding protein gene gene321 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01600 BCI_RS01605 BCI_0325 BCI_RS01605 349081 349776 + arginine ABC transporter permease with ArtPMJI transports arginine across the inner membrane gene gene322 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01605 BCI_RS01610 BCI_0326 artM artM 349798 350469 + arginine transporter permease subunit ArtM with ArtPQJI acts to transport arginine across the inner membrane gene gene323 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01610 BCI_RS01615 BCI_0327 rpsJ rpsJ 350805 351116 + 30S ribosomal protein S10 NusE%3B involved in assembly of the 30S subunit%3B in the ribosome%2C this protein is involved in the binding of tRNA%3B in Escherichia coli this protein was also found to be involved in transcription antitermination%3B NusB/S10 heterodimers bind boxA sequences in the leader RNA of rrn operons which is required for antitermination%3B binding of NusB/S10 to boxA nucleates assembly of the antitermination complex gene gene324 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01615 BCI_RS01620 BCI_0328 BCI_RS01620 351142 351780 + 50S ribosomal protein L3 gene gene325 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01620 BCI_RS01625 BCI_0329 rplD rplD 351792 352397 + 50S ribosomal protein L4 L4 is important during the early stages of 50S assembly%3B it initially binds near the 5' end of the 23S rRNA gene gene326 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01625 BCI_RS01630 BCI_0330 BCI_RS01630 352394 352696 + 50S ribosomal protein L23 gene gene327 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01630 BCI_RS01635 BCI_0331 BCI_RS01635 352716 353534 + 50S ribosomal protein L2 gene gene328 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01635 BCI_RS01640 BCI_0332 BCI_RS01640 353556 353834 + 30S ribosomal protein S19 gene gene329 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01640 BCI_RS01645 BCI_0333 BCI_RS01645 353865 354197 + 50S ribosomal protein L22 gene gene330 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01645 BCI_RS01650 BCI_0334 BCI_RS01650 354214 354915 + 30S ribosomal protein S3 gene gene331 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01650 BCI_RS01655 BCI_0335 BCI_RS01655 354927 355340 + 50S ribosomal protein L16 gene gene332 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01655 BCI_RS01660 BCI_0336 BCI_RS01660 355337 355528 + 50S ribosomal protein L29 one of the stabilizing components for the large ribosomal subunit gene gene333 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01660 BCI_RS01665 BCI_0337 BCI_RS01665 355584 355790 + 30S ribosomal protein S17 gene gene334 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01665 BCI_RS01670 BCI_RS01670 BCI_RS01670 355945 356313 + 50S ribosomal protein L14 gene gene335 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01670 BCI_RS01675 BCI_0339 BCI_RS01675 356325 356639 + 50S ribosomal protein L24 gene gene336 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01675 BCI_RS01680 BCI_0340 BCI_RS01680 356663 357208 + 50S ribosomal protein L5 gene gene337 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01680 BCI_RS01685 BCI_0341 rpsN rpsN 357231 357536 + 30S ribosomal protein S14 located in the peptidyl transferase center and involved in assembly of 30S ribosome subunit%3B similar to what is observed with proteins L31 and L33%2C some proteins in this family contain CXXC motifs that are involved in zinc binding%3B if two copies are present in a genome%2C then the duplicated copy appears to have lost the zinc-binding motif and is instead regulated by zinc%3B the proteins in this group do not appear to have the zinc-binding motif gene gene338 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01685 BCI_RS01690 BCI_0342 BCI_RS01690 357569 357967 + 30S ribosomal protein S8 gene gene339 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01690 BCI_RS01695 BCI_0343 BCI_RS01695 357982 358515 + 50S ribosomal protein L6 gene gene340 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01695 BCI_RS01700 BCI_0344 BCI_RS01700 358529 358876 + 50S ribosomal protein L18 gene gene341 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01700 BCI_RS01705 BCI_0345 BCI_RS01705 358888 359391 + 30S ribosomal protein S5 gene gene342 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01705 BCI_RS01710 BCI_0346 rpmD rpmD 359395 359577 + 50S ribosomal protein L30 L30 binds domain II of the 23S rRNA and the 5S rRNA%3B similar to eukaryotic protein L7 gene gene343 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01710 BCI_RS01715 BCI_0347 BCI_RS01715 359578 360009 + 50S ribosomal protein L15 gene gene344 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01715 BCI_RS01720 BCI_0348 secY secY 360025 361359 + preprotein translocase subunit SecY forms heterotrimeric complex in the membrane%3B in bacteria the complex consists of SecY which forms the channel pore and SecE and SecG%3B the SecG subunit is not essential%3B in bacteria translocation is driven via the SecA ATPase gene gene345 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01720 BCI_RS01725 BCI_0349 BCI_RS01725 361397 361513 + 50S ribosomal protein L36 gene gene346 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01725 BCI_RS01730 BCI_0350 BCI_RS01730 361539 361895 + 30S ribosomal protein S13 gene gene347 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01730 BCI_RS01735 BCI_0351 BCI_RS01735 361920 362309 + 30S ribosomal protein S11 gene gene348 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01735 BCI_RS01740 BCI_0352 BCI_RS01740 362356 362976 + 30S ribosomal protein S4 gene gene349 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01740 BCI_RS01745 BCI_0353 BCI_RS01745 362997 363980 + DNA-directed RNA polymerase subunit alpha catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Dimerization of the alpha subunit is the first step in the sequential assembly of subunits to form the holoenzyme gene gene350 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01745 BCI_RS01750 BCI_0354 BCI_RS01750 364044 364430 + 50S ribosomal protein L17 gene gene351 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01750 BCI_RS01755 BCI_0355 BCI_RS01755 364453 364530 - tRNA-Thr tRNA gene352 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01755 BCI_RS01760 BCI_0356 BCI_RS01760 364558 364629 - tRNA-Gly tRNA gene353 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01760 BCI_RS01765 BCI_0357 BCI_RS01765 364646 364727 - tRNA-Tyr tRNA gene354 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01765 BCI_RS01770 BCI_0358 BCI_RS01770 364746 364818 - tRNA-Thr tRNA gene355 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01770 BCI_RS01775 BCI_0359 BCI_RS01775 365089 366036 + type I pantothenate kinase gene gene356 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01775 BCI_RS01780 BCI_0360 BCI_RS01780 366098 367033 + 50S ribosomal protein L30 involved in methylation of ribosomal protein L3 gene gene357 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01780 BCI_RS01785 BCI_0361 BCI_RS01785 367048 368115 + chorismate synthase catalyzes the formation of chorismate from 5-O-(1-carboxyvinyl)-3-phosphoshikimate in aromatic amino acid biosynthesis gene gene358 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01785 BCI_RS01790 BCI_0362 BCI_RS01790 368366 369586 + 3-oxoacyl-ACP synthase FabB%2C beta-Ketoacyl-ACP synthase I%2C KASI%3B catalyzes a condensation reaction in fatty acid biosynthesis: addition of an acyl acceptor of two carbons from malonyl-ACP%3B required for the elongation of short-chain unsaturated acyl-ACP gene gene359 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01790 BCI_RS01795 BCI_0363 BCI_RS01795 369660 370790 + erythronate-4-phosphate dehydrogenase catalyzes the formation of 3-hydroxy-2-oxo-4-phosphonooxybutanoate from erythronate-4-phosphate gene gene360 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01795 BCI_RS01800 BCI_0364 truA truA 370798 371601 + tRNA pseudouridine synthase A mediates pseudouridylation (positions 38%2C 39%2C 40) at the tRNA anticodon region which contributes to the structural stability gene gene361 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01800 BCI_RS01805 BCI_0365 BCI_RS01805 371713 372600 + acetyl-CoA carboxylase carboxyltransferase subunit beta catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer of AccA2D2 subunits gene gene362 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01805 BCI_RS01810 BCI_0366 BCI_RS01810 372643 373923 + bifunctional folylpolyglutamate synthase/ dihydrofolate synthase gene gene363 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01810 BCI_RS01815 BCI_0367 BCI_RS01815 374317 374802 + colicin V production protein membrane protein required for colicin V production gene gene364 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01815 BCI_RS01820 BCI_0368 BCI_RS01820 374842 376260 + amidophosphoribosyltransferase Catalyzes first step of the de novo purine nucleotide biosynthetic pathway gene gene365 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01820 BCI_RS01825 BCI_0369 BCI_RS01825 376380 377834 - NADH-quinone oxidoreductase subunit N Catalyzes the transfer of electrons from NADH to quinone gene gene366 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01825 BCI_RS01830 BCI_0370 BCI_RS01830 377859 379382 - NADH:ubiquinone oxidoreductase subunit M gene gene367 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01830 BCI_RS01835 BCI_0371 BCI_RS01835 379432 381297 - NADH:ubiquinone oxidoreductase subunit L Catalyzes the transfer of electrons from NADH to ubiquinone gene gene368 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01835 BCI_RS01840 BCI_0372 BCI_RS01840 381294 381596 - NADH-quinone oxidoreductase subunit K gene gene369 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01840 BCI_RS01845 BCI_0373 BCI_RS01845 381644 382141 - NADH:ubiquinone oxidoreductase subunit J Catalyzes the transfer of electrons from NADH to quinone gene gene370 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01845 BCI_RS01850 BCI_0374 BCI_RS01850 382165 382707 - NADH-quinone oxidoreductase subunit I gene gene371 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01850 BCI_RS01855 BCI_0375 BCI_RS01855 382731 383708 - NADH:ubiquinone oxidoreductase gene gene372 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01855 BCI_RS01860 BCI_0376 BCI_RS01860 383705 386434 - NADH dehydrogenase subunit G Catalyzes the transfer of electrons from NADH to quinone gene gene373 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01860 BCI_RS01865 BCI_0377 BCI_RS01865 386516 387850 - NADH dehydrogenase subunit F part of NADH-ubiquinone oxidoreductase complex I%3B shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B NuoF is part of the soluble NADH dehydrogenase fragment%2C which represents the electron input part of NADH dehydrogenase gene gene374 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01865 BCI_RS01870 BCI_0378 BCI_RS01870 387847 388350 - NADH dehydrogenase subunit E Catalyzes the transfer of electrons from NADH to quinone gene gene375 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01870 BCI_RS01875 BCI_0379 BCI_RS01875 388353 390140 - bifunctional NADH:ubiquinone oxidoreductase subunit C/D NuoCD%3B NDH-1 shuttles electrons from NADH%2C via FMN and iron-sulfur (Fe-S) centers%2C to quinones in the respiratory chain%3B subunits NuoCD%2C E%2C F%2C and G constitute the peripheral sector of the complex%3B in Escherichia coli this gene encodes a fusion protein of NuoC and NuoD that are found separate in other organisms gene gene376 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01875 BCI_RS01880 BCI_0380 BCI_RS01880 390249 390923 - NADH-quinone oxidoreductase subunit B gene gene377 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01880 BCI_RS01885 BCI_0381 BCI_RS01885 390987 391373 - NADH-quinone oxidoreductase subunit A gene gene378 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01885 BCI_RS01890 BCI_0382 BCI_RS01890 391621 392823 + acetate kinase AckA utilizes acetate and can acetylate CheY which increases signal strength during flagellar rotation%3B utilizes magnesium and ATP%3B also involved in conversion of acetate to aceyl-CoA%3B also known to act on propionate gene gene379 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01890 BCI_RS01895 BCI_0383 BCI_RS01895 392877 395012 + phosphate acetyltransferase catalyzes the synthesis of acetylphosphate or propionylphosphate from acetyl-CoA or propionyl-CoA and inorganic phosphate%3B when using propionyl-CoA the enzyme is functioning in the anaerobic pathway catabolizing threonine to propionate gene gene380 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01895 BCI_RS01900 BCI_0384 BCI_RS01900 395031 395297 - 2Fe-2S ferredoxin gene gene381 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01900 BCI_RS01905 BCI_0385 BCI_RS01905 395299 396429 - ribonucleotide-diphosphate reductase subunit beta B2 or R2 protein%3B type 1a enzyme%3B catalyzes the rate-limiting step in dNTP synthesis%3B converts nucleotides to deoxynucleotides%3B forms a homodimer and then a multimeric complex with NrdA gene gene382 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01905 BCI_RS01910 BCI_0386 BCI_RS01910 396480 398762 - ribonucleotide-diphosphate reductase subunit alpha Catalyzes the rate-limiting step in dNTP synthesis gene gene383 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01910 BCI_RS01915 BCI_0387 BCI_RS01915 399298 401832 + DNA gyrase subunit A gene gene384 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01915 BCI_RS01920 BCI_RS01920 BCI_RS01920 402460 402663 - hypothetical protein gene gene385 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01920 BCI_RS01925 BCI_RS01925 BCI_RS01925 402928 403143 - hypothetical protein gene gene386 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01925 BCI_RS01930 BCI_0389 BCI_RS01930 403289 403362 - tRNA-Pro tRNA gene387 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01930 BCI_RS01935 BCI_0390 BCI_RS01935 403459 403743 - 50S ribosomal protein L25 the Ctc family of proteins consists of two types%2C one that contains the N-terminal ribosomal protein L25 domain only which in Escherichia coli binds the 5S rRNA while a subset of proteins contain a C-terminal extension that is involved in the stress response gene gene388 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01935 BCI_RS01940 BCI_RS01940 BCI_RS01940 403876 404295 - hypothetical protein gene gene389 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01940 BCI_RS01945 BCI_0392 BCI_RS01945 404495 405373 - endonuclease V Assists in DNA repair by cleaving phosphodiester bonds at apurinic or apyrimidinic sties to produce new 5' ends that are base-free deoxyribose 5-phosphate residues gene gene390 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01945 BCI_RS01950 BCI_0393 BCI_RS01950 405526 407004 + lysine transporter gene gene391 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01950 BCI_RS01955 BCI_0394 folE folE 407148 407810 + GTP cyclohydrolase 1 involved in the first step of tetrahydrofolate biosynthesis%3B catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1%2C2%2C3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water%3B forms a homopolymer gene gene392 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01955 BCI_RS01960 BCI_0395 BCI_RS01960 407840 408421 - deoxycytidine triphosphate deaminase gene gene393 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01960 BCI_RS01965 BCI_0396 BCI_RS01965 408614 410257 + methionine--tRNA ligase gene gene394 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01965 BCI_RS01970 BCI_0397 BCI_RS01970 410283 411689 - 6-phosphogluconate dehydrogenase catalyzes the formation of D-ribulose 5-phosphate from 6-phospho-D-gluconate gene gene395 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01970 BCI_RS01975 BCI_0398 BCI_RS01975 411892 412515 - phosphoribosyl-AMP cyclohydrolase catalyzes the formation of 1-(5-phosphoribosyl)-AMP from 1-(5-phosphoribosyl)-ATP and the subsequent formation of 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide from 1-(5-phosphoribosyl)-AMP in histidine biosynthesis gene gene396 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01975 BCI_RS01980 BCI_0399 BCI_RS01980 412509 413285 - imidazole glycerol phosphate synthase subunit HisF gene gene397 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01980 BCI_RS01985 BCI_0400 BCI_RS01985 413267 414013 - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase gene gene398 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01985 BCI_RS01990 BCI_0401 hisH hisH 414016 414609 - imidazole glycerol phosphate synthase subunit HisH with HisF IGPS catalyzes the conversion of phosphoribulosyl-formimino-5-aminoimidazole-4-carboxamide ribonucleotide phosphate and glutamine to imidazole-glycerol phosphate%2C 5-aminoimidazol-4-carboxamide ribonucleotide%2C and glutamate in histidine biosynthesis%3B the HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of imidazole-glycerol phosphate and 5-aminoimidazol-4-carboxamide ribonucleotide gene gene399 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01990 BCI_RS01995 BCI_0402 BCI_RS01995 414606 415676 - histidine biosynthesis bifunctional protein HisB catalyzes the formation of 3-(imidazol-4-yl)-2-oxopropyl phosphate from D-ethythro-1-(imidazol-4-yl)glycerol 3-phosphate and histidinol from histidinol phosphate gene gene400 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS01995 BCI_RS02000 BCI_0403 BCI_RS02000 415682 416764 - histidinol-phosphate aminotransferase catalyzes the formation of L-histidinol phosphate from imidazole-acetol phosphate and glutamate in histidine biosynthesis gene gene401 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02000 BCI_RS02005 BCI_0404 hisD hisD 416761 418074 - bifunctional histidinal dehydrogenase/ histidinol dehydrogenase catalyzes the oxidation of L-histidinol to L-histidinaldehyde and then to L-histidine in histidine biosynthesis%3B functions as a dimer gene gene402 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02005 BCI_RS02010 BCI_0405 hisG hisG 418078 418977 - ATP phosphoribosyltransferase long form of enzyme%3B catalyzes the formation of N'-5'-phosphoribosyl-ATP from phosphoribosyl pyrophosphate%3B crucial role in histidine biosynthesis%3B forms active dimers and inactive hexamers which is dependent on concentration of substrates and inhibitors gene gene403 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02010 BCI_RS02015 BCI_0406 BCI_RS02015 419623 420252 + hypothetical protein gene gene404 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02015 BCI_RS02020 BCI_0407 BCI_RS02020 420279 421469 - aromatic amino acid aminotransferase gene gene405 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02020 BCI_RS02025 BCI_0408 BCI_RS02025 421550 422953 - asparagine--tRNA ligase gene gene406 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02025 BCI_RS02030 BCI_0409 BCI_RS02030 423379 424389 + dihydroorotate dehydrogenase catalyzes the conversion of dihydroorotate to orotate in the pyrimidine biosynthesis pathway%3B uses a flavin nucleotide as an essential cofactor%3B class 2 enzymes are monomeric and compared to the class 1 class 2 possess an extended N terminus%2C which plays a role in the membrane association of the enzyme and provides the binding site for the respiratory quinones that serve as physiological electron acceptors gene gene407 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02030 BCI_RS02035 BCI_0410 BCI_RS02035 424522 425043 - 3-hydroxydecanoyl-ACP dehydratase catalyzes the dehydration of (3R)-3-hydroxydecanoyl-ACP to 2%2C3-decenoyl-ACP or 3%2C4-decenoyl-ACP gene gene408 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02035 BCI_RS02040 BCI_0411 BCI_RS02040 425090 426844 - ATP-dependent protease gene gene409 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02040 BCI_RS02045 BCI_0412 BCI_RS02045 427111 427428 - heat-shock protein HspQ gene gene410 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02045 BCI_RS02050 BCI_RS02050 BCI_RS02050 427534 427860 - sulfur transfer protein TusE transfers sulfur from TusBCD complex to MnmA%3B involved in thiouridation of U34 position of some tRNAs gene gene411 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02050 BCI_RS02055 BCI_0414 BCI_RS02055 428047 428131 + tRNA-Ser tRNA gene412 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02055 BCI_RS02060 BCI_0415 fmt fmt 428219 429154 - methionyl-tRNA formyltransferase modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet) which is important in translation initiation%3B inactivation of this gene in Escherichia coli severely impairs growth gene gene413 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02060 BCI_RS02065 BCI_0416 BCI_RS02065 429204 429707 - peptide deformylase gene gene414 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02065 BCI_RS02070 BCI_0417 BCI_RS02070 429939 430535 + tRNA(ANN) t(6)A37 threonylcarbamoyladenosine modification protein involved in the biosynthesis of the threonylcarbamoyladenosine (t6A) residue at position 37 of ANN-decoding tRNAs gene gene415 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02070 BCI_RS02075 BCI_0418 BCI_RS02075 430556 431383 + shikimate dehydrogenase gene gene416 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02075 BCI_RS02080 BCI_0419 BCI_RS02080 431428 434919 - pyruvate-flavodoxin oxidoreductase gene gene417 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02080 BCI_RS02085 BCI_0420 fumC fumC 434949 436340 - fumarate hydratase class II family (does not require metal)%3B tetrameric enzyme%3B fumarase C%3B reversibly converts (S)-malate to fumarate and water%3B functions in the TCA cycle gene gene418 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02085 BCI_RS02090 BCI_0421 BCI_RS02090 436947 437022 + tRNA-Asn tRNA gene419 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02090 BCI_RS02095 BCI_0422 mnmA mnmA 437170 438279 + tRNA 2-thiouridylase catalyzes a sulfuration reaction to synthesize 2-thiouridine at the U34 position of tRNAs gene gene420 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02095 BCI_RS02100 BCI_0423 BCI_RS02100 438606 439997 + adenylosuccinate lyase Catalyzes two discrete reactions in the de novo synthesis of purines: the cleavage of adenylosuccinate and succinylaminoimidazole carboxamide ribotide gene gene421 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02100 BCI_RS02105 BCI_0424 BCI_RS02105 440033 441280 - transporter part of the ATP-dependent transport system LolCDE%3B responsible for the localization of lipoproteins to the periplasmic surface of the outer membrane gene gene422 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02105 BCI_RS02110 BCI_0425 lolD lolD 441277 441987 - peptide ABC transporter ATP-binding protein outer membrane specific%3B part of transporter complex lolCDE involved in the translocation of mature outer membrane-directed lipoproteins%2C from the inner membrane to the periplasmic chaperone gene gene423 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02110 BCI_RS02115 BCI_0426 BCI_RS02115 441980 443173 - transporter gene gene424 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02115 BCI_RS02120 BCI_0427 BCI_RS02120 443281 443814 - hypothetical protein gene gene425 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02120 BCI_RS02125 BCI_0428 BCI_RS02125 443829 444194 - purine nucleoside phosphoramidase gene gene426 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02125 BCI_RS02130 BCI_0429 BCI_RS02130 444191 444991 - DNAse gene gene427 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02130 BCI_RS02135 BCI_0430 BCI_RS02135 445036 446034 - DNA polymerase III%2C delta' subunit gene gene428 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02135 BCI_RS02140 BCI_0431 BCI_RS02140 446037 446675 - thymidylate kinase gene gene429 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02140 BCI_RS02145 BCI_0432 BCI_RS02145 446730 447533 - 4-amino-4-deoxychorismate lyase catalyzes the formation of 4-aminobenzoate and pyruvate from 4-amino-4-deoxychorismate gene gene430 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02145 BCI_RS02150 BCI_0433 BCI_RS02150 447634 447867 - acyl carrier protein carries the fatty acid chain in fatty acid biosynthesis gene gene431 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02150 BCI_RS02155 BCI_0434 fabG fabG 448023 448757 - 3-ketoacyl-ACP reductase catalyzes the first of the two reduction steps in the elongation cycle of fatty acid synthesis gene gene432 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02155 BCI_RS02160 BCI_0435 BCI_RS02160 448741 449703 - malonyl CoA-ACP transacylase gene gene433 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02160 BCI_RS02165 BCI_0436 BCI_RS02165 449723 450676 - 3-oxoacyl-ACP synthase III FabH%3B beta-ketoacyl-acyl carrier protein synthase III%3B catalyzes the condensation of acetyl-CoA with malonyl-ACP to initiate cycles of fatty acid elongation%3B differs from 3-oxoacyl-(acyl carrier protein) synthase I and II in that it utilizes CoA thioesters as primers rather than acyl-ACPs gene gene434 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02165 BCI_RS02170 BCI_0438 rpmF rpmF 451081 451251 - 50S ribosomal protein L32 some L32 proteins have zinc finger motifs consisting of CXXC while others do not gene gene435 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02170 BCI_RS02175 BCI_0439 BCI_RS02175 451394 452362 - 23S rRNA pseudouridylate synthase C catalyzes the transformation of uracil to pseudouracil at nucleotides U955%2C U2504%2C and U2580 in 23S rRNA gene gene436 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02175 BCI_RS02180 BCI_0440 BCI_RS02180 452883 454394 + ribonuclease E gene gene437 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02180 BCI_RS02185 BCI_0441 BCI_RS02185 455035 456099 + dihydroorotase gene gene438 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02185 BCI_RS02190 BCI_0442 BCI_RS02190 456227 458071 + signal peptide peptidase SppA SppA%3B catalyzes the degradation of cleaved signal peptides%3B essential to maintain secretion of mature proteins across the membrane gene gene439 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02190 BCI_RS02195 BCI_0443 BCI_RS02195 458189 459187 + glyceraldehyde-3-phosphate dehydrogenase gene gene440 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02195 BCI_RS02200 BCI_0444 minC minC 459430 460125 + septum site-determining protein MinC blocks the formation of polar Z-ring septums gene gene441 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02200 BCI_RS02205 BCI_0445 BCI_RS02205 460142 460954 + cell division inhibitor MinD ATPase%3B with MinC inhibits cell division by blocking formation of the polar Z ring septums gene gene442 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02205 BCI_RS02210 BCI_0446 minE minE 460958 461239 + cell division topological specificity factor works in conjunction with MinC and MinD to enable cell division at the midpoint of the long axis of the cell gene gene443 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02210 BCI_RS02215 BCI_0447 BCI_RS02215 461260 461958 - tRNA threonylcarbamoyladenosine biosynthesis protein TsaB gene gene444 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02215 BCI_RS02220 BCI_0448 BCI_RS02220 462025 462957 - L%2CD-transpeptidase catalyzes th removal of D-alanine and attachment of the murein lipoprotein to the peptidoglycan tetrapeptide chain gene gene445 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02220 BCI_RS02225 BCI_0449 BCI_RS02225 463060 463899 - PTS mannose transporter subunit IID hosphoenolpyruvate-dependent sugar phosphotransferase system catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B IID with IIC forms the translocation channel gene gene446 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02225 BCI_RS02230 BCI_0450 BCI_RS02230 463921 464721 - PTS mannose transporter subunit IIC catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B the IIC domain forms the PTS system translocation channel and contains the specific substrate-binding site gene gene447 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02230 BCI_RS02235 BCI_0451 BCI_RS02235 464758 465726 - PTS mannose transporter subunit IIAB catalyzes the phosphorylation of incoming sugar substrates concomitant with their translocation across the cell membrane%3B subunit IIA transfers a phosphoryl group to subunit IIB%3B subunit IIB transfers the phosphoryl group to the substrate gene gene448 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02235 BCI_RS02240 BCI_0452 BCI_RS02240 466225 467559 + tellurium resistance protein TerC gene gene449 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02240 BCI_RS02245 BCI_0453 BCI_RS02245 467724 469082 - aminodeoxychorismate synthase component I gene gene450 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02245 BCI_RS02250 BCI_0454 BCI_RS02250 469204 470178 + sulfurtransferase gene gene451 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02250 BCI_RS02255 BCI_0455 BCI_RS02255 470183 470258 - tRNA-Ala tRNA gene452 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02255 BCI_RS02260 BCI_0456 gltX gltX 470279 471679 - glutamate--tRNA ligase catalyzes a two-step reaction%2C first charging an glutamate molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B contains discriminating and non-discriminating subtypes gene gene453 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02260 BCI_RS02265 BCI_0457 BCI_RS02265 471790 471862 + tRNA-Val tRNA gene454 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02265 BCI_RS02270 BCI_0458 BCI_RS02270 471901 471976 + tRNA-Lys tRNA gene455 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02270 BCI_RS02275 BCI_0459 emrB emrB 472023 473543 - multidrug resistance protein B multidrug MFS transporte%3B with EmrA is involved in resistance to hydrophobic antibiotics such as nalidixic acid gene gene456 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02275 BCI_RS02280 BCI_0460 BCI_RS02280 473575 474729 - hypothetical protein gene gene457 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02280 BCI_RS02285 BCI_0461 BCI_RS02285 475083 475499 - cysteine desufuration protein SufE Acts with SufS to catalyze the formation of L-alanine from L-cysteine gene gene458 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02285 BCI_RS02290 BCI_0462 BCI_RS02290 475533 476756 - bifunctional cysteine desulfurase/selenocysteine lyase gene gene459 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02290 BCI_RS02295 BCI_0463 BCI_RS02295 476753 478051 - Fe-S cluster assembly protein SufD gene gene460 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02295 BCI_RS02300 BCI_0464 sufC sufC 478032 478772 - Fe-S cluster assembly ATPase SufC part of SUF system involved in inserting iron-sulfur clusters into proteins%3B in Escherichia coli this protein forms a complex with SufBD%3B the SufBCD complex stimulates the cysteine desulfurase SufS in conjunction with SufE gene gene461 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02300 BCI_RS02305 BCI_0465 BCI_RS02305 478847 480304 - cysteine desulfurase with SufCD activates cysteine desulfurase SufS gene gene462 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02305 BCI_RS02310 BCI_0466 sufA sufA 480337 480696 - (Fe-S)-cluster assembly protein functions as a scaffold on which iron-sulfur clusters ([2Fe-2S]%3B [4Fe-4S]) are assembled%3B forms a homodimer%3B similar to IscA protein gene gene463 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02310 BCI_RS02315 BCI_0467 BCI_RS02315 480843 483227 - phenylalanine--tRNA ligase subunit beta gene gene464 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02315 BCI_RS02320 BCI_0468 BCI_RS02320 483244 484227 - phenylalanyl-tRNA synthetase subunit alpha gene gene465 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02320 BCI_RS02325 BCI_0469 rplT rplT 484295 484657 - 50S ribosomal protein L20 binds directly to 23S ribosomal RNA prior to in vitro assembly of the 50S ribosomal subunit gene gene466 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02325 BCI_RS02330 BCI_0470 BCI_RS02330 484685 484882 - 50S ribosomal protein L35 gene gene467 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02330 BCI_RS02335 BCI_0471 BCI_RS02335 484928 485443 - translation initiation factor IF-3 gene gene468 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02335 BCI_RS02340 BCI_0472 thrS thrS 485475 487403 - threonine--tRNA ligase catalyzes a two-step reaction%2C first charging a threonine molecule by linking its carboxyl group to the alpha-phosphate of ATP%2C followed by transfer of the aminoacyl-adenylate to its tRNA%3B catalyzes the formation of threonyl-tRNA(Thr) from threonine and tRNA(Thr) gene gene469 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02340 BCI_RS02345 BCI_0473 BCI_RS02345 487653 488375 - DNA polymerase III subunit epsilon 3'-5' exonuclease of DNA polymerase III gene gene470 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02345 BCI_RS02350 BCI_0474 BCI_RS02350 488425 488886 + ribonuclease H gene gene471 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02350 BCI_RS02355 BCI_0475 BCI_RS02355 488971 489744 + hydroxyacylglutathione hydrolase catalyzes the hydrolysis of S-D-lactoylglutathione to D-lactic acid and reduced glutathione%3B plays an important role in cellular detoxification using glutathione gene gene472 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02355 BCI_RS02360 BCI_0476 BCI_RS02360 489766 490602 - hypothetical protein gene gene473 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02360 BCI_RS02365 BCI_0477 mltC mltC 490684 491739 - murein transglycosylase Murein hydrolase C%3B membrane-bound%3B lytic%3B catalyzes the cleavage of the beta-1%2C4-glycosidic bond between N-acetylmuramic acid and N-acetylglucosamine residues gene gene474 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02365 BCI_RS02370 BCI_0478 BCI_RS02370 491812 492045 - Fe(2+)-trafficking protein gene gene475 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02370 BCI_RS02375 BCI_0479 BCI_RS02375 492130 493218 - coproporphyrinogen III oxidase gene gene476 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02375 BCI_RS02380 BCI_RS02380 BCI_RS02380 493244 493691 - Holliday junction resolvase similar to RuvC resolvase with substantial differences%3B NMR structural information suggests this protein is monomeric%3B unknown cellular function gene gene477 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02380 BCI_RS02385 BCI_0481 BCI_RS02385 493691 494254 - hypothetical protein gene gene478 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02385 BCI_RS02390 BCI_0482 BCI_RS02390 494302 495255 - glutathione synthetase catalyzes the second step in the glutathione biosynthesis pathway%2C where it synthesizes ATP + gamma-L-glutamyl-L-cysteine + glycine %3D ADP + phosphate + glutathione gene gene479 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02390 BCI_RS02395 BCI_0483 BCI_RS02395 495314 495937 - superoxide dismutase SodA%3B manganese binding%3B only present under aerobic conditions%3B destroys free radicals gene gene480 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02395 BCI_RS02400 BCI_0484 BCI_RS02400 495970 496542 - fe/S biogenesis protein nfuA cytoplasmic protein that may be involved in the utilization of double-stranded DNA as a carbon source gene gene481 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02400 BCI_RS02405 BCI_0485 BCI_RS02405 496690 497451 + pimeloyl-[acyl-carrier protein] methyl ester esterase gene gene482 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02405 BCI_RS02410 BCI_0486 BCI_RS02410 497561 497634 + tRNA-Ile tRNA gene483 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02410 BCI_RS02415 BCI_0487 BCI_RS02415 497662 497734 + tRNA-Ala tRNA gene484 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02415 BCI_RS02420 BCI_0488 BCI_RS02420 497784 498227 + transcriptional regulator Acts as a negative controlling element%2C employing Zn(2+) as a cofactor to bind the operator of the repressed genes znuACB gene gene485 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02420 BCI_RS02425 BCI_0489 BCI_RS02425 498343 498714 + sulfur transfer complex subunit TusD in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene486 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02425 BCI_RS02430 BCI_0490 BCI_RS02430 498726 499085 + sulfur relay protein TusC gene gene487 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02430 BCI_RS02435 BCI_0491 BCI_RS02435 499095 499382 + sulfur transfer complex subunit TusB in Escherichai coli the heterohexameric TusBCD complex is involved in sulfur related that results in thiouridation to U34 position in some tRNAs gene gene488 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02435 BCI_RS02440 BCI_0492 BCI_RS02440 499440 499814 + 30S ribosomal protein S12 gene gene489 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02440 BCI_RS02445 BCI_0493 BCI_RS02445 499873 500343 + 30S ribosomal protein S7 gene gene490 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02445 BCI_RS02450 BCI_0494 fusA fusA 500448 502565 + elongation factor G EF-G%3B promotes GTP-dependent translocation of the ribosome during translation%3B many organisms have multiple copies of this gene gene gene491 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02450 BCI_RS02455 BCI_0495 tuf tuf 502681 503865 + elongation factor Tu EF-Tu%3B promotes GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis%3B when the tRNA anticodon matches the mRNA codon%2C GTP hydrolysis results%3B the inactive EF-Tu-GDP leaves the ribosome and release of GDP is promoted by elongation factor Ts%3B many prokaryotes have two copies of the gene encoding EF-Tu gene gene492 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02455 BCI_RS02460 BCI_0496 BCI_RS02460 503931 504314 + preprotein translocase subunit SecE gene gene493 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02460 BCI_RS02465 BCI_0497 nusG nusG 504315 504860 + transcription termination/antitermination factor NusG Modulates Rho-dependent transcription termination gene gene494 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02465 BCI_RS02470 BCI_0498 BCI_RS02470 504916 505344 + 50S ribosomal protein L11 gene gene495 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02470 BCI_RS02475 BCI_0499 BCI_RS02475 505348 506052 + 50S ribosomal protein L1 gene gene496 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02475 BCI_RS02480 BCI_0500 BCI_RS02480 506232 506732 + 50S ribosomal protein L10 gene gene497 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02480 BCI_RS02485 BCI_0501 BCI_RS02485 506768 507133 + 50S ribosomal protein L7/L12 gene gene498 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02485 BCI_RS02490 BCI_0502 rpoB rpoB 507307 511329 + DNA-directed RNA polymerase subunit beta DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates%3B beta subunit is part of the catalytic core which binds with a sigma factor to produce the holoenzyme gene gene499 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02490 BCI_RS02495 BCI_0503 BCI_RS02495 511418 515644 + DNA-directed RNA polymerase subunit beta' DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Subunit beta' binds to sigma factor allowing it to bind to the -10 region of the promoter gene gene500 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02495 BCI_RS02500 BCI_0504 murB murB 515662 516690 + UDP-N-acetylenolpyruvoylglucosamine reductase catalyzes the reduction of UDP-N-acetylglucosamine enolpyruvate to form UDP-N-acetylmuramate in peptidoglycan biosynthesis gene gene501 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02500 BCI_RS02505 BCI_0505 BCI_RS02505 516668 517540 + hypothetical protein gene gene502 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02505 BCI_RS02510 BCI_0157 BCI_RS02510 517581 517695 - 5S ribosomal RNA rRNA gene503 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02510 BCI_RS02515 BCI_0156 BCI_RS02515 517718 520641 - 23S ribosomal RNA rRNA gene504 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02515 BCI_RS02520 BCI_0155 BCI_RS02520 520716 520788 - tRNA-Glu tRNA gene505 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02520 BCI_RS02525 BCI_0154 BCI_RS02525 520892 522457 - 16S ribosomal RNA rRNA gene506 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02525 BCI_RS02530 BCI_0510 BCI_RS02530 522858 524270 - dihydrolipoamide dehydrogenase E3 component of pyruvate and 2-oxoglutarate dehydrogenase complex%3B catalyzes the oxidation of dihydrolipoamide to lipoamide gene gene507 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02530 BCI_RS02535 BCI_0511 BCI_RS02535 524329 525618 - branched-chain alpha-keto acid dehydrogenase subunit E2 gene gene508 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02535 BCI_RS02540 BCI_0512 aceE aceE 525629 528298 - pyruvate dehydrogenase E1 component%3B part of pyruvate dehydrogenase%3B forms a complex with DlaT and LpdC gene gene509 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02540 BCI_RS02545 BCI_0513 BCI_RS02545 528653 529540 + nicotinate-nucleotide pyrophosphorylase catalyzes the formation of pyridine-2%2C3-dicarboxylate and 5-phospho-alpha-D-ribose 1-diphosphate from nictinate D-ribonucleotide gene gene510 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02545 BCI_RS02550 BCI_0514 coaE coaE 529591 530202 + dephospho-CoA kinase catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A%3B involved in coenzyme A biosynthesis gene gene511 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02550 BCI_RS02555 BCI_RS02555 secA secA 530233 532893 - preprotein translocase subunit SecA functions in protein export%3B can interact with acidic membrane phospholipids and the SecYEG protein complex%3B binds to preproteins%3B binds to ATP and undergoes a conformational change to promote membrane insertion of SecA/bound preprotein%3B ATP hydrolysis appears to drive release of the preprotein from SecA and deinsertion of SecA from the membrane%3B additional proteins SecD/F/YajC aid SecA recycling%3B exists in an equilibrium between monomers and dimers%3B may possibly form higher order oligomers%3B proteins in this cluster correspond SecA1%3B SecA2 is not essential and seems to play a role in secretion of a subset of proteins gene gene512 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02555 BCI_RS02560 BCI_0516 BCI_RS02560 533136 533657 + hypothetical protein gene gene513 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02560 BCI_RS02565 BCI_0517 BCI_RS02565 533781 534953 - peptidase M23 GTPase%3B similar structure to tubulin%3B forms ring-shaped polymers at the site of cell division%3B other proteins such as FtsA%2C ZipA%2C and ZapA%2C interact with and regulate FtsZ function gene gene514 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02565 BCI_RS02570 BCI_0518 BCI_RS02570 535265 536737 - UDP-N-acetylmuramate--L-alanine ligase gene gene515 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02570 BCI_RS02575 BCI_0519 murG murG 536809 537885 - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase N-acetylglucosaminyl transferase%3B UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase%3B involved in cell wall formation%3B inner membrane-associated%3B last step of peptidoglycan synthesis gene gene516 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02575 BCI_RS02580 BCI_0520 murD murD 538203 539543 - UDP-N-acetylmuramoylalanine--D-glutamate ligase UDP-N-acetylmuramoylalanine--D-glutamate ligase%3B involved in peptidoglycan biosynthesis%3B cytoplasmic%3B catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation gene gene517 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02580 BCI_RS02585 BCI_0521 mraY mraY 539545 540627 - phospho-N-acetylmuramoyl-pentapeptide transferase First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan gene gene518 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02585 BCI_RS02590 BCI_0522 murF murF 540621 541982 - UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase gene gene519 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02590 BCI_RS02595 BCI_0523 murE murE 541985 543472 - UDP-N-acetylmuramoylalanyl-D-glutamate--2%2C 6-diaminopimelate ligase involved in cell wall formation%3B peptidoglycan synthesis%3B cytoplasmic enzyme%3B catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-aceylmuramoyl-l-alanyl-d-glutamate gene gene520 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02595 BCI_RS02600 BCI_0524 BCI_RS02600 543659 544612 - ribosomal RNA small subunit methyltransferase H gene gene521 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02600 BCI_RS02605 BCI_0525 BCI_RS02605 544713 545567 - NADPH-dependent 7-cyano-7-deazaguanine reductase gene gene522 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02605 BCI_RS02610 BCI_0526 BCI_RS02610 545764 546558 - methionine aminopeptidase catalyzes the removal of N-terminal amino acids from peptides and arylamides%3B generally Co(II) however activity has been shown for some methionine aminopeptidases with Zn%2C Fe%2C or Mn gene gene523 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02610 BCI_RS02615 BCI_0527 BCI_RS02615 546863 547561 + gene gene524 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02615 BCI_RS02620 BCI_0528 tsf tsf 547604 548446 + elongation factor Ts EF-Ts%3B functions during elongation stage of protein translation%3B forms a dimer%3B associates with EF-Tu-GDP complex and promotes exchange of GDP to GTP resulting in regeneration of the active form of EF-Tu gene gene525 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02620 BCI_RS02625 BCI_0529 BCI_RS02625 548506 549255 + uridylate kinase gene gene526 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02625 BCI_RS02630 BCI_0530 frr frr 549304 549861 + ribosome-recycling factor Rrf%3B Frr%3B ribosome-recycling factor%3B release factor 4%3B RF4%3B recycles ribosomes upon translation termination along with release factor RF-3 and elongation factor EF-G%3B A GTPase-dependent process results in release of 50S from 70S%3B inhibited by release factor RF-1%3B essential for viability%3B structurally similar to tRNAs gene gene527 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02630 BCI_RS02635 BCI_0531 BCI_RS02635 550015 551211 + 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzes the formation of 2-C-methyl-D-erythritol 4-phosphate from 1-deoxy-D-xylulose-5-phosphate gene gene528 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02635 BCI_RS02640 BCI_0532 BCI_RS02640 551341 552102 + UDP pyrophosphate synthase catalyzes the formation of undecaprenyl pyrophosphate from isopentenyl pyrophosphate gene gene529 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02640 BCI_RS02645 BCI_0533 BCI_RS02645 552112 552966 + CDP-diglyceride synthase gene gene530 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02645 BCI_RS02650 BCI_0534 BCI_RS02650 552986 554365 + zinc metallopeptidase RseP catalyzes the cleavage of RseA which activates the sigmaE-mediated stress response gene gene531 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02650 BCI_RS02655 BCI_0535 BCI_RS02655 554346 556751 + hypothetical protein gene gene532 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02655 BCI_RS02660 BCI_0536 BCI_RS02660 556830 557327 + molecular chaperone gene gene533 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02660 BCI_RS02665 BCI_0537 BCI_RS02665 557583 558032 + 3-hydroxyacyl-ACP dehydratase gene gene534 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02665 BCI_RS02670 BCI_0538 dnaE dnaE 558257 561748 + DNA polymerase III subunit alpha catalyzes DNA-template-directed extension of the 3'- end of a DNA strand by one nucleotide at a time%3B main replicative polymerase gene gene535 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02670 BCI_RS02675 BCI_0539 BCI_RS02675 561765 562724 + acetyl-CoA carboxylase carboxyltransferase subunit alpha catalyzes the carboxylation of acetyl-CoA to malonyl-CoA%3B forms a tetramer composed of two alpha (AccA) and two beta (AccD) subunits%3B one of the two catalytic subunits that can form the acetyl CoA carboxylase enzyme together with a carrier protein gene gene536 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02675 BCI_RS02680 BCI_0540 BCI_RS02680 562746 563936 - cystathionine beta-lyase catalyzes the formation of L-homocysteine from cystathionine gene gene537 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02680 BCI_RS02685 BCI_0541 BCI_RS02685 564244 564918 + DNA mismatch repair protein gene gene538 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02685 BCI_RS02690 BCI_0542 BCI_RS02690 565076 565555 + RNA pyrophosphohydrolase hydrolyzes diadenosine polyphosphate gene gene539 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02690 BCI_RS02695 BCI_0543 BCI_RS02695 565763 566620 + prolipoprotein diacylglyceryl transferase transfers the N-acyl diglyceride moiety to the prospective N-terminal cysteine in prolipoprotein gene gene540 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02695 BCI_RS02700 BCI_0544 BCI_RS02700 566651 567445 + thymidylate synthase gene gene541 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02700 BCI_RS02705 BCI_0545 recC recC 567517 570813 + exonuclease V subunit gamma catalyzes ATP-dependent exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield 5'-phosphooligonucleotides%3B component of the RecBCD (Exo V) helicase/nuclease complex that is essential for recombination gene gene542 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02705 BCI_RS02710 BCI_0546 BCI_RS02710 570857 574408 + exodeoxyribonuclease V%2C subunit beta gene gene543 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02710 BCI_RS02715 BCI_0547 BCI_RS02715 574456 576315 + exodeoxyribonuclease V%2C subunit alpha gene gene544 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02715 BCI_RS02720 BCI_0548 BCI_RS02720 576514 577146 + transcriptional regulator cAMP receptor protein%3B complexes with cyclic AMP and binds to specific DNA sites near the promoter to regulate the transcription of several catabolite-sensitive operons gene gene545 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02720 BCI_RS02725 BCI_0549 BCI_RS02725 577230 577820 - anthranilate synthase subunit II TrpG%3B with TrpE catalyzes the formation of anthranilate and glutamate from chorismate and glutamine%3B TrpG provides the glutamine amidotransferase activity gene gene546 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02725 BCI_RS02730 BCI_0550 BCI_RS02730 577980 579392 + DNA helicase unwinds double stranded DNA gene gene547 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02730 BCI_RS02735 BCI_0551 BCI_RS02735 579471 579543 + tRNA-Arg tRNA gene548 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02735 BCI_RS02740 BCI_0552 dnaK dnaK 579809 581704 + molecular chaperone DnaK heat shock protein 70%3B assists in folding of nascent polypeptide chains%3B refolding of misfolded proteins%3B utilizes ATPase activity to help fold%3B co-chaperones are DnaJ and GrpE%3B multiple copies in some bacteria gene gene549 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02740 BCI_RS02745 BCI_0553 BCI_RS02745 581803 582921 + molecular chaperone DnaJ chaperone Hsp40%3B co-chaperone with DnaK%3B Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins%2C also in an autonomous%2C dnaK-independent fashion gene gene550 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02745 BCI_RS02750 BCI_0554 rpsT rpsT 582954 583217 - 30S ribosomal protein S20 binds directly to the 16S rRNA and is involved in post-translational inhibition of arginine and ornithine decarboxylase gene gene551 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02750 BCI_RS02755 BCI_0555 BCI_RS02755 583427 584410 + bifunctional riboflavin kinase/FMN adenylyltransferase gene gene552 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02755 BCI_RS02760 BCI_0556 ileS ileS 584422 587238 + isoleucine--tRNA ligase IleRS%3B catalyzes the formation of isoleucyl-tRNA(Ile) from isoleucine and tRNA(Ile)%3B since isoleucine and other amino acids such as valine are similar%2C there are additional editing function in this enzyme%3B one is involved in hydrolysis of activated valine-AMP and the other is involved in deacylation of mischarged Val-tRNA(Ile)%3B there are two active sites%2C one for aminoacylation and one for editing%3B class-I aminoacyl-tRNA synthetase family type 1 subfamily%3B some organisms carry two different copies of this enzyme gene gene553 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02760 BCI_RS02765 BCI_0557 lspA lspA 587238 587741 + lipoprotein signal peptidase lipoprotein signal peptidase%3B integral membrane protein that removes signal peptides from prolipoproteins during lipoprotein biosynthesis gene gene554 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02765 BCI_RS02770 BCI_0558 ispH ispH 587770 588711 + 4-hydroxy-3-methylbut-2-enyl diphosphate reductase catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP)%3B functions in the nonmevalonate isoprenoid biosynthesis pathway gene gene555 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02770 BCI_RS02775 BCI_0559 BCI_RS02775 588861 590006 + carbamoyl phosphate synthase small subunit catalyzes production of carbamoyl phosphate from bicarbonate and glutamine in pyrimidine and arginine biosynthesis pathways%3B forms an octamer composed of four CarAB dimers gene gene556 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02775 BCI_RS02780 BCI_0560 carB carB 590025 593264 + carbamoyl phosphate synthase large subunit four CarB-CarA dimers form the carbamoyl phosphate synthetase holoenzyme that catalyzes the production of carbamoyl phosphate%3B CarB is responsible for the amidotransferase activity gene gene557 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02780 BCI_RS02785 BCI_0561 folA folA 593307 593804 + dihydrofolate reductase catalyzes the reduction of dihydrofolate to tetrahydrofolate gene gene558 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02785 BCI_RS02790 BCI_0562 BCI_RS02790 593806 594672 - bis(5'-nucleosyl)-tetraphosphatase symmetrical gene gene559 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02790 BCI_RS02795 BCI_0563 ksgA ksgA 594902 595717 - ribosomal RNA small subunit methyltransferase A in Escherichia coli this enzyme catalyzes the transfer of a total of four methyl groups from S-adenosyl-l-methionine (S-AdoMet) to two adjacent adenosine bases A1518 and A1519 in 16S rRNA%3B mutations in ksgA causes resistance to the translation initiation inhibitor kasugamycin%3B members of this protein family have secondary functions gene gene560 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02795 BCI_RS02800 BCI_0564 pdxA pdxA 595710 596714 - 4-hydroxythreonine-4-phosphate dehydrogenase catalyzes oxidation of 4-(phosphohydroxy)-L-threonine into 2-amino-3-oxo-4-(phosphohydroxy)butyric acid which decarboxylates to form 1-amino-3-(phosphohydroxy)propan-2-one (3-amino-2-oxopropyl phosphate) gene gene561 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02800 BCI_RS02805 BCI_0565 BCI_RS02805 596701 598068 - hypothetical protein gene gene562 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02805 BCI_RS02810 BCI_0566 BCI_RS02810 598051 598383 + small protein A gene gene563 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02810 BCI_RS02815 BCI_0567 BCI_RS02815 598411 598686 - hypothetical protein gene gene564 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02815 BCI_RS02820 BCI_0568 smpB smpB 598916 599401 + SsrA-binding protein binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes%3B also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site%3B SmpB protects the tmRNA from RNase R degradation in Caulobacter crescentus%3B both the tmRNA and SmpB are regulated in cell cycle-dependent manner%3B functions in release of stalled ribosomes from damaged mRNAs and targeting proteins for degradation gene gene565 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02820 BCI_RS02825 BCI_0570 BCI_RS02825 599882 600625 - 3'-5'-bisphosphate nucleotidase catalyzes the formation of AMP from adenosine-3'%2C5'-bisphosphate gene gene567 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02825 BCI_RS02830 BCI_0571 rplI rplI 600646 601098 - 50S ribosomal protein L9 in Escherichia coli this protein is wrapped around the base of the L1 stalk gene gene568 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02830 BCI_RS02835 BCI_0572 rpsR rpsR 601184 601411 - 30S ribosomal protein S18 binds as a heterodimer with protein S6 to the central domain of the 16S rRNA%3B helps stabilize the platform of the 30S subunit gene gene569 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02835 BCI_RS02840 BCI_0573 BCI_RS02840 601415 601729 - primosomal replication protein N binds single-stranded DNA at the primosome assembly site gene gene570 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02840 BCI_RS02845 BCI_0574 rpsF rpsF 601772 602149 - 30S ribosomal protein S6 binds cooperatively with S18 to the S15-16S complex%2C allowing platform assembly to continue with S11 and S21 gene gene571 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02845 BCI_RS02850 BCI_0575 BCI_RS02850 602303 603049 - 23S rRNA (guanosine-2'-O-)-methyltransferase Specifically methylates the ribose of guanosine 2251 in 23S rRNA gene gene572 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02850 BCI_RS02855 BCI_0576 BCI_RS02855 603138 605387 - exoribonuclease R 3'-5'exoribonuclease that acts nonspecifically on poly(A)%2C poly(U) and ribosomal RNAs gene gene573 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02855 BCI_RS02860 BCI_0577 BCI_RS02860 605490 606788 - adenylosuccinate synthetase catalyzes the formation of N6-(1%2C2%2C-dicarboxyethyl)-AMP from L-aspartate%2C inosine monophosphate and GTP in AMP biosynthesis gene gene574 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02860 BCI_RS02865 BCI_0578 BCI_RS02865 606892 607893 - cell division protein FtsH with HflK inhibits proteolysis of lambda cII protein by FtsH gene gene575 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02865 BCI_RS02870 BCI_0579 BCI_RS02870 607900 609060 - cell division protein FtsH with HflC inhibits proteolysis of lambda cII protein by FtsH gene gene576 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02870 BCI_RS02875 BCI_0580 BCI_RS02875 609103 610386 - GTP-binding protein involved in modulation of proteins HflK and HflC%3B part of the hflA locus (high frequency of lysogenization) which governs the lysis-lysogeny decision of bacteriophage lambda by controlling stability of the phage cII protein gene gene577 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02875 BCI_RS02880 BCI_0581 BCI_RS02880 610494 610754 - RNA chaperone Hfq gene gene578 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02880 BCI_RS02885 BCI_0583 miaA miaA 611067 612002 - tRNA dimethylallyltransferase IPP transferase%3B isopentenyltransferase%3B involved in tRNA modification%3B in Escherichia coli this enzyme catalyzes the addition of a delta2-isopentenyl group from dimethylallyl diphosphate to the N6-nitrogen of adenosine adjacent to the anticodon of tRNA species that read codons starting with uracil%3B further tRNA modifications may occur%3B mutations in miaA result in defects in translation efficiency and fidelity gene gene579 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02885 BCI_RS02890 BCI_0584 BCI_RS02890 612006 613814 - DNA mismatch repair protein MutL gene gene580 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02890 BCI_RS02895 BCI_0585 BCI_RS02895 613891 615039 - N-acetylmuramoyl-L-alanine amidase gene gene581 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02895 BCI_RS02900 BCI_0586 BCI_RS02900 615477 616031 - oligoribonuclease 3'-5' exoribonuclease specific for small oligoribonuclotides gene gene582 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02900 BCI_RS02905 BCI_0587 BCI_RS02905 616407 617285 + phosphatidylserine decarboxylase proenzyme gene gene583 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02905 BCI_RS02910 BCI_0588 BCI_RS02910 617561 618544 - elongation factor P--(R)-beta-lysine ligase poxA%3B regulates pyruvate oxidase poxB gene gene584 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02910 BCI_RS02915 BCI_0589 BCI_RS02915 618632 619201 - elongation factor P gene gene585 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02915 BCI_RS02920 BCI_0590 BCI_RS02920 619235 620254 + EF-P beta-lysylation protein EpmB gene gene586 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02920 BCI_RS02925 BCI_0591 groEL groEL 620344 621984 - molecular chaperone GroEL 60 kDa chaperone family%3B promotes refolding of misfolded polypeptides especially under stressful conditions%3B forms two stacked rings of heptamers to form a barrel-shaped 14mer%3B ends can be capped by GroES%3B misfolded proteins enter the barrel where they are refolded when GroES binds%3B many bacteria have multiple copies of the groEL gene which are active under different environmental conditions%3B the B.japonicum protein in this cluster is expressed constitutively%3B in Rhodobacter%2C Corynebacterium and Rhizobium this protein is essential for growth gene gene587 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02925 BCI_RS02930 BCI_0592 groES groES 622026 622319 - molecular chaperone GroES 10 kDa chaperonin%3B Cpn10%3B GroES%3B forms homoheptameric ring%3B binds to one or both ends of the GroEL double barrel in the presence of adenine nucleotides capping it%3B folding of unfolded substrates initiates in a GroEL-substrate bound and capped by GroES%3B release of the folded substrate is dependent on ATP binding and hydrolysis in the trans ring gene gene588 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02930 BCI_RS02935 BCI_0593 aspA aspA 622572 623990 + aspartate ammonia-lyase catalyzes the formation of fumarate from aspartate gene gene589 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02935 BCI_RS02940 BCI_0594 BCI_RS02940 624068 624140 + tRNA-Phe tRNA gene590 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02940 BCI_RS02945 BCI_0595 BCI_RS02945 624393 624995 - peroxiredoxin gene gene591 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02945 BCI_RS02950 BCI_0596 queA queA 625182 626243 + S-adenosylmethionine:tRNA ribosyltransferase-isomerase Synthesizes oQ from preQ1 in a single S-adenosylmethionine-requiring step gene gene592 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02950 BCI_RS02955 BCI_0597 tgt tgt 626305 627417 + queuine tRNA-ribosyltransferase Exchanges the guanine residue with 7-aminomethyl-7-deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp%2C -Asn%2C -His and -Tyr) gene gene593 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02955 BCI_RS02960 BCI_0598 yajC yajC 627439 627771 + preprotein translocase subunit YajC member of preprotein translocase%3B forms a heterotrimer with SecD and SecF%3B links the SecD/SecF/YajC/YidC complex with the SecY/SecE/SecG complex gene gene594 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02960 BCI_RS02965 BCI_0599 secD secD 627805 629643 + preprotein translocase subunit SecD part of the preprotein secretory system%3B when complexed with proteins SecF and YajC%2C SecDFyajC stimulates the proton motive force-driven protein translocation%2C and appears to be required for the release of mature proteins from the extracytoplasmic side of the membrane gene gene595 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02965 BCI_RS02970 BCI_0600 BCI_RS02970 629654 630574 + preprotein translocase subunit SecF gene gene596 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02970 BCI_RS02975 BCI_0601 ribD ribD 630850 631986 + diaminohydroxyphosphoribosylaminopyrimidine deaminase riboflavin biosynthesis protein which catalyzes the deamination and reduction steps in the riboflavin biosynthesis pathway%3B catalyzes the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 2%2C5-diamino-6-hydroxy-4-(5-phosphoribosylamino)pyrimidine and the formation of 5-amino-6-(5-phosphoribosylamino)uracil from 5-amino-6-(5-phosphoribitylamino)uracil gene gene597 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02975 BCI_RS02980 BCI_0602 ribH ribH 632101 632574 + 6%2C7-dimethyl-8-ribityllumazine synthase RibE%3B 6%2C7-diimethyl-8-ribityllumazine synthase%3B DMRL synthase%3B lumazine synthase%3B beta subunit of riboflavin synthase%3B condenses 5-amino-6-(1'-D)-ribityl-amino-2%2C4(1H%2C3H)-pyrimidinedione with L-3%2C4-dihydrohy-2-butanone-4-phosphate to generate 6%2C6-dimethyl-8-lumazine (DMRL)%3B riboflavin synthase then uses 2 molecules of DMRL to produce riboflavin (vitamin B12)%3B involved in the last steps of riboflavin biosynthesis%3B forms a 60mer (icosahedral shell) in both Bacillus subtilis and Escherichia coli%3B in Bacillus subtilis this 60mer is associated with the riboflavin synthase subunit (alpha) while in Escherichia coli it is not gene gene598 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02980 BCI_RS02985 BCI_0603 nusB nusB 632601 633020 + N utilization substance protein B homolog Regulates rRNA biosynthesis by transcriptional antitermination gene gene599 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02985 BCI_RS02990 BCI_0604 BCI_RS02990 633102 634079 + thiamine monophosphate kinase catalyzes the formation of thiamine diphosphate from thiamine phosphate ant ATP gene gene600 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02990 BCI_RS02995 BCI_0605 BCI_RS02995 634087 634593 + phosphatidylglycerophosphatase A hydrolyzes phosphatidylglycerophosphate to produce phosphatidylglycerol and phosphate gene gene601 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS02995 BCI_RS03000 BCI_0606 BCI_RS03000 634648 636423 + membrane protein gene gene602 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03000 BCI_RS03005 BCI_0607 BCI_RS03005 636537 639368 + hypothetical protein gene gene603 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03005 BCI_RS03010 BCI_0608 BCI_RS03010 639384 639917 - inorganic pyrophosphatase catalyzes the hydrolysis of pyrophosphate to phosphate gene gene604 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03010 BCI_RS03015 BCI_0609 BCI_RS03015 640077 641750 - proline--tRNA ligase catalyzes the formation of prolyl-tRNA(Pro) from proline and tRNA(Pro) gene gene605 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03015 BCI_RS03020 BCI_0610 BCI_RS03020 641839 641924 - tRNA-Leu tRNA gene606 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03020 BCI_RS03025 BCI_0611 ppnK ppnK 642053 642958 - inorganic polyphosphate/ATP-NAD kinase catalyzes the phosphorylation of NAD to NADP gene gene607 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03025 BCI_RS03030 BCI_0612 BCI_RS03030 643042 643638 + protein GrpE with DnaK and DnaJ acts in response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins%3B may act as a thermosensor gene gene608 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03030 BCI_RS03035 BCI_0613 BCI_RS03035 643689 644357 - uracil-DNA glycosylase Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine gene gene609 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03035 BCI_RS03040 BCI_0614 BCI_RS03040 644411 646060 - L-aspartate oxidase catalyzes the formation of oxaloacetate from L-aspartate gene gene610 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03040 BCI_RS03045 BCI_0615 BCI_RS03045 646228 646303 - tRNA-Met tRNA gene611 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03045 BCI_RS03050 BCI_0616 BCI_RS03050 646370 648208 - RNA polymerase sigma factor RpoD sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released%3B this is the primary sigma factor of bacteria gene gene612 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03050 BCI_RS03055 BCI_0617 dnaG dnaG 648290 650077 - DNA primase synthesizes RNA primers at the replication forks gene gene613 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03055 BCI_RS03060 BCI_0618 rpsU rpsU 650171 650386 - 30S ribosomal protein S21 a small basic protein that is one of the last in the subunit assembly%3B omission does not prevent assembly but the subunit is inactive%3B binds central domain of 16S rRNA gene gene614 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03060 BCI_RS03065 BCI_0619 BCI_RS03065 650587 651612 + tRNA N6-adenosine threonylcarbamoyltransferase universal genome maintenance protein%3B Kae1/Qri7/OSGEP/YgjD family protein%3B in Archaea%2C some Kae1 are found as fusion proteins similar to two distinct proteins in yeast that are involved in the KEOPS complex%3B kinase associated endopeptidase 1 (Kae1) and a serine/threonine protein kinase (Bud32)%3B in Pyrococcus Kae1 has atypical AP endonuclease activity and inhibits the kinase activity of Bud32%3B the protein is essential in Escherichia coli and Bacillus subtilis gene gene615 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03065 BCI_RS03070 BCI_0620 folB folB 651654 652019 + dihydroneopterin triphosphate 2'-epimerase catalyzes the conversion of 7%2C8-dihydroneopterin to 6-hydroxymethyl-7%2C8-dihydropterin and can also catalyze the epimerization of carbon 2' of dihydroneopterin and dihydromonapterin gene gene616 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03070 BCI_RS03075 BCI_0621 BCI_RS03075 652158 652985 + undecaprenyl-diphosphatase BacA%3B phosphatase activity in Escherichia coli not kinase%3B involved in bacitracin resistance as bacitracin supposedly sequesters undecaprenyl disphosphate which reduces the pool of lipid carrier available to the cell gene gene617 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03075 BCI_RS03080 BCI_0622 BCI_RS03080 653051 654289 - multifunctional CCA protein gene gene618 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03080 BCI_RS03085 BCI_0623 ribB ribB 655168 655803 + 3%2C4-dihydroxy-2-butanone 4-phosphate synthase DHBP synthase%3B functions during riboflavin biosynthesis gene gene619 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03085 BCI_RS03090 BCI_0624 BCI_RS03090 655968 656717 - 1-acyl-sn-glycerol-3-phosphate acyltransferase gene gene620 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03090 BCI_RS03095 BCI_0625 BCI_RS03095 656963 657370 - DNA polymerase III%2C psi subunit gene gene621 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03095 BCI_RS03100 BCI_0626 BCI_RS03100 657363 659138 - RNA helicase participates in the assembly of the large subunit of the ribosome%3B plays a key role in optimal cell growth at low temperature and is required for normal cell division gene gene622 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03100 BCI_RS03105 BCI_0627 BCI_RS03105 659552 661645 - polyribonucleotide nucleotidyltransferase gene gene623 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03105 BCI_RS03110 BCI_0628 BCI_RS03110 661756 662025 - 30S ribosomal protein S15 gene gene624 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03110 BCI_RS03115 BCI_0629 truB truB 662146 663099 - tRNA pseudouridine synthase B catalyzes isomerization of specific uridines in RNA to pseudouridine%3B responsible for residues in T loops of many tRNAs gene gene625 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03115 BCI_RS03120 BCI_0630 BCI_RS03120 663102 663506 - ribosome-binding factor A gene gene626 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03120 BCI_RS03125 BCI_0631 infB infB 663575 666217 - translation initiation factor IF-2 Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits during initiation of protein synthesis. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex gene gene627 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03125 BCI_RS03130 BCI_0632 nusA nusA 666244 667731 - transcription termination factor NusA modifies transcription through interactions with RNA polymerase affecting elongation%2C readthrough%2C termination%2C and antitermination gene gene628 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03130 BCI_RS03135 BCI_0633 BCI_RS03135 667937 668013 - tRNA-Met tRNA gene629 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03135 BCI_RS03140 BCI_0634 BCI_RS03140 668074 668164 - tRNA-Leu tRNA gene630 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03140 BCI_RS03145 BCI_0635 BCI_RS03145 668231 668509 - preprotein translocase subunit SecG gene gene631 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03145 BCI_RS03150 BCI_0636 glmM glmM 668611 669948 - phosphoglucosamine mutase catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate gene gene632 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03150 BCI_RS03155 BCI_0637 folP folP 669945 670811 - dihydropteroate synthase catalyzes the formation of dihydropteroate from 2-amino-4-hydroxy-6-hydroxymethyl-7%2C8-dihydropteridine diphosphate and 4-aminobenzoate gene gene633 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03155 BCI_RS03160 BCI_0638 hflB hflB 670920 672803 - ATP-dependent metalloprotease inner membrane metalloprotease%3B may be involved in degradation of aberrant cytoplasmic and membrane proteins gene gene634 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03160 BCI_RS03165 BCI_0639 rrmJ rrmJ 672862 673491 - ribosomal RNA large subunit methyltransferase E Specifically methylates the uridine in position 2552 of 23S rRNA in the fully assembled 50S ribosomal subunit gene gene635 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03165 BCI_RS03170 BCI_0640 greA greA 673768 674244 - transcription elongation factor GreA necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites%3B arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through%2C resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus gene gene636 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03170 BCI_RS03175 BCI_0641 BCI_RS03175 674447 675874 + D-alanyl-D-alanine carboxypeptidase penicillin binding protein 4%3B penicillin sensitive%3B catalyzes the formation of D-alanine from D-alanyl-D-alanine%3B one of four%2C DD-carboxypeptidase low-molecular weight penicillin-binding proteins that remove terminal D-alanine from pentapeptide side chains gene gene637 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03175 BCI_RS03180 BCI_0642 obgE obgE 675884 676894 - GTPase Obg ObgE%3B essential GTPase%3B exhibits high exchange rate for GTP/GDP%3B associates with 50S ribosomal subunit%3B involved in regulation of chromosomal replication gene gene638 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03180 BCI_RS03185 BCI_0643 rpmA rpmA 676946 677200 - 50S ribosomal protein L27 involved in the peptidyltransferase reaction during translation gene gene639 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03185 BCI_RS03190 BCI_0644 rplU rplU 677215 677526 - 50S ribosomal protein L21 gene gene640 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03190 BCI_RS03195 BCI_0645 BCI_RS03195 677988 679151 + phosphoglycerate kinase gene gene641 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03195 BCI_RS03200 BCI_0646 BCI_RS03200 679230 680306 + fructose-bisphosphate aldolase catalyzes the formation of glycerone phosphate and glyceraldehyde 3-phosphate from fructose 1%2C6%2C bisphosphate gene gene642 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03200 BCI_RS03205 BCI_0647 BCI_RS03205 680448 681119 + ribose-5-phosphate isomerase A gene gene643 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03205 BCI_RS03210 BCI_0648 BCI_RS03210 681172 681780 - 5-formyltetrahydrofolate cyclo-ligase gene gene644 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03210 BCI_RS03215 BCI_0649 BCI_RS03215 681939 682742 - bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase catalyzes the formation hydroxymethylpyrimidine phosphate from hydroxymethylpyrimidine and the formation of of 4-amino-2-methyl-5-diphosphomethylpyrimidine from hydroxymethylpyrimidine phosphate gene gene645 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03215 BCI_RS03220 BCI_0650 guaA guaA 682912 684492 - GMP synthase [glutamine-hydrolyzing] contains glutamine-hydrolyzing domain and glutamine amidotransferase%3B GMP-binding domain%3B functions to produce GMP from XMP in the IMP pathway gene gene646 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03220 BCI_RS03225 BCI_0651 BCI_RS03225 684542 685999 - inosine-5-monophosphate dehydrogenase gene gene647 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03225 BCI_RS03240 BCI_RS03240 BCI_RS03240 599480 599854 + gene gene566 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03240 BCI_RS03245 BCI_RS03245 BCI_RS03245 79623 80054 - cell division protein ZipA gene gene67 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03245 BCI_RS03250 BCI_0089 BCI_RS03250 101593 101937 + major outer membrane lipoprotein gene gene88 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03250 BCI_RS03255 BCI_RS03255 BCI_RS03255 137224 137427 + hypothetical protein gene gene123 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03255 BCI_RS03260 BCI_RS03260 BCI_RS03260 137672 137887 + hypothetical protein gene gene124 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03260 BCI_RS03265 BCI_RS03265 BCI_RS03265 37463 37827 - bacterial RNase P ncRNA gene26 http://www.ncbi.nlm.nih.gov/gene/?term=BCI_RS03265