locus-tag	class	description
BDT_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BDT_RS00020	COG0187	DNA topoisomerase II activity
BDT_RS00025	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BDT_RS00045	COG0356	it plays a direct role in the translocation of protons across the membrane
BDT_RS00050	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BDT_RS00065	COG0789	Transcriptional regulator
BDT_RS00075	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BDT_RS00080	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BDT_RS00090	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BDT_RS00100	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BDT_RS00105	COG2086	electron transfer activity
BDT_RS00115	COG1053	succinate dehydrogenase
BDT_RS00145	COG0360	Binds together with S18 to 16S ribosomal RNA
BDT_RS00155	COG0359	binds to the 23S rRNA
BDT_RS00175	COG0305	Participates in initiation and elongation during chromosome replication
BDT_RS00185	COG0602	queuosine metabolic process
BDT_RS00210	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BDT_RS00215	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BDT_RS00220	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BDT_RS00230	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BDT_RS00245	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BDT_RS00265	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BDT_RS00270	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BDT_RS00275	COG0154	amidase activity
BDT_RS00280	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BDT_RS00285	COG0248	Ppx GppA phosphatase
BDT_RS00315	COG0254	rRNA binding
BDT_RS00320	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BDT_RS00325	COG2890	protein-(glutamine-N5) methyltransferase activity
BDT_RS00330	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BDT_RS00360	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BDT_RS00375	COG0586	Pfam SNARE associated Golgi protein
BDT_RS00420	COG3550	peptidyl-serine autophosphorylation
BDT_RS00425	COG0590	tRNA wobble adenosine to inosine editing
BDT_RS00435	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BDT_RS00475	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BDT_RS00480	COG0459	protein refolding
BDT_RS00495	COG2201	protein-glutamate methylesterase activity
BDT_RS00570	COG0840	transmembrane signaling receptor activity
BDT_RS00575	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BDT_RS00575	COG0037	tRNA processing
BDT_RS00585	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BDT_RS00595	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BDT_RS00600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BDT_RS00615	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BDT_RS00625	COG0527	aspartate kinase activity
BDT_RS00635	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BDT_RS00640	COG1217	gtp-binding protein TYPA
BDT_RS00660	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BDT_RS00670	COG0671	phosphoesterase, PA-phosphatase related
BDT_RS00675	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BDT_RS00685	COG1472	Belongs to the glycosyl hydrolase 3 family
BDT_RS00710	COG3876	Protein conserved in bacteria
BDT_RS00715	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BDT_RS00735	COG0668	transmembrane transport
BDT_RS00740	COG1132	(ABC) transporter
BDT_RS00760	COG1970	mechanosensitive ion channel activity
BDT_RS00775	COG2884	Cell division ATP-binding protein ftsE
BDT_RS00780	COG2177	Part of the ABC transporter FtsEX involved in
BDT_RS00790	COG0793	Belongs to the peptidase S41A family
BDT_RS00810	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BDT_RS00820	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BDT_RS00825	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BDT_RS00830	COG0823	Involved in the tonB-independent uptake of proteins
BDT_RS00860	COG0719	Fe-S assembly protein
BDT_RS00865	COG0396	ATPase activity
BDT_RS00870	COG0719	Fe-S assembly protein
BDT_RS00875	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BDT_RS00900	COG1570	exodeoxyribonuclease VII activity
BDT_RS00905	COG1722	exodeoxyribonuclease VII activity
BDT_RS00910	COG0142	geranyltranstransferase activity
BDT_RS00915	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BDT_RS00925	COG0006	proline dipeptidase activity
BDT_RS00950	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BDT_RS00965	COG1077	Cell shape determining protein MreB Mrl
BDT_RS01015	COG2003	Belongs to the UPF0758 family
BDT_RS01030	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BDT_RS01055	COG2766	serine protein kinase
BDT_RS01060	COG2718	Belongs to the UPF0229 family
BDT_RS01065	COG2719	SpoVR family
BDT_RS01080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BDT_RS01085	COG0513	Belongs to the DEAD box helicase family
BDT_RS01095	COG0861	Integral membrane protein TerC family
BDT_RS01105	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BDT_RS01115	COG0358	DNA primase activity
BDT_RS01150	COG1401	restriction endodeoxyribonuclease activity
BDT_RS01205	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BDT_RS01240	COG0582	viral genome integration into host DNA
BDT_RS01285	COG3237	CsbD-like
BDT_RS01290	COG0322	excinuclease ABC activity
BDT_RS01340	COG0509	glycine decarboxylation via glycine cleavage system
BDT_RS01360	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BDT_RS01365	COG0653	protein targeting
BDT_RS01400	COG0318	PFAM AMP-dependent synthetase and ligase
BDT_RS01405	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BDT_RS01410	COG1028	Short-chain dehydrogenase reductase Sdr
BDT_RS01440	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BDT_RS01445	COG1845	cytochrome c oxidase, subunit III
BDT_RS01455	COG0109	protoheme IX farnesyltransferase activity
BDT_RS01480	COG2032	superoxide dismutase activity
BDT_RS01485	COG2373	Large extracellular alpha-helical protein
BDT_RS01490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BDT_RS01505	COG0784	Response regulator, receiver
BDT_RS01505	COG2205	protein histidine kinase activity
BDT_RS01505	COG5002	protein histidine kinase activity
BDT_RS01520	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BDT_RS01530	COG0604	alcohol dehydrogenase
BDT_RS01560	COG3135	benzoate transporter
BDT_RS01565	COG0357	Ribosomal RNA small subunit methyltransferase G
BDT_RS01575	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
BDT_RS01585	COG0724	RNA recognition motif
BDT_RS01590	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BDT_RS01595	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BDT_RS01600	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BDT_RS01605	COG0513	Belongs to the DEAD box helicase family
BDT_RS01610	COG5002	protein histidine kinase activity
BDT_RS01625	COG0386	Belongs to the glutathione peroxidase family
BDT_RS01630	COG3315	Exhibits S-adenosyl-L-methionine-dependent methyltransferase activity
BDT_RS01635	COG1028	Short-chain dehydrogenase reductase Sdr
BDT_RS01670	COG2807	transmembrane transport
BDT_RS01695	COG1666	GTP binding
BDT_RS01700	COG0724	RNA recognition motif
BDT_RS01710	COG1136	(ABC) transporter
BDT_RS01715	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BDT_RS01720	COG0009	L-threonylcarbamoyladenylate synthase
BDT_RS01745	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BDT_RS01755	COG0010	Belongs to the arginase family
BDT_RS01760	COG4166	transmembrane transport
BDT_RS01765	COG4174	ABC transporter (Permease)
BDT_RS01770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BDT_RS01785	COG1166	arginine decarboxylase activity
BDT_RS01790	COG0495	leucyl-tRNA aminoacylation
BDT_RS01800	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BDT_RS01805	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BDT_RS01830	COG0745	RESPONSE REGULATOR receiver
BDT_RS01880	COG0587	DNA-directed DNA polymerase activity
BDT_RS01905	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BDT_RS01930	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BDT_RS01935	COG2814	Major facilitator Superfamily
BDT_RS01950	COG0739	heme binding
BDT_RS01970	COG0183	Belongs to the thiolase family
BDT_RS01990	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BDT_RS01995	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BDT_RS02045	COG0848	biopolymer transport protein
BDT_RS02050	COG0811	peptide transport
BDT_RS02055	COG0583	DNA-binding transcription factor activity
BDT_RS02060	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BDT_RS02065	COG0557	exoribonuclease II activity
BDT_RS02095	COG0745	RESPONSE REGULATOR receiver
BDT_RS02110	COG5006	permease, DMT superfamily
BDT_RS02120	COG0745	RESPONSE REGULATOR receiver
BDT_RS02145	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BDT_RS02170	COG1079	Belongs to the binding-protein-dependent transport system permease family
BDT_RS02175	COG4603	Belongs to the binding-protein-dependent transport system permease family
BDT_RS02180	COG3845	ABC transporter
BDT_RS02185	COG1744	ABC transporter substrate-binding protein PnrA-like
BDT_RS02190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BDT_RS02195	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BDT_RS02205	COG4232	protein-disulfide reductase activity
BDT_RS02250	COG0525	valine-tRNA ligase activity
BDT_RS02275	COG1872	DUF167
BDT_RS02285	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BDT_RS02290	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BDT_RS02300	COG0726	polysaccharide deacetylase
BDT_RS02305	COG0424	maF-like protein
BDT_RS02330	COG1716	ATPase activity
BDT_RS02370	COG1183	phosphatidylcholine synthase activity
BDT_RS02375	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BDT_RS02405	COG0101	tRNA pseudouridine synthase activity
BDT_RS02410	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BDT_RS02415	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BDT_RS02450	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BDT_RS02460	COG1408	metallophosphoesterase
BDT_RS02490	COG1267	Lipid phosphatase which dephosphorylates phosphatidylglycerophosphate (PGP) to phosphatidylglycerol (PG)
BDT_RS02495	COG1546	Belongs to the CinA family
BDT_RS02495	COG1058	Belongs to the CinA family
BDT_RS02500	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BDT_RS02505	COG3189	MarR family transcriptional regulator
BDT_RS02535	COG0386	Belongs to the glutathione peroxidase family
BDT_RS02560	COG0741	lytic transglycosylase activity
BDT_RS02560	COG1388	LysM domain
BDT_RS02565	COG4786	Flagellar basal body rod
BDT_RS02570	COG4786	Flagellar basal body rod
BDT_RS02575	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BDT_RS02585	COG1706	bacterial-type flagellum-dependent cell motility
BDT_RS02610	COG1256	bacterial-type flagellum assembly
BDT_RS02625	COG1699	Binds to the C-terminal region of flagellin, which is implicated in polymerization, and participates in the assembly of the flagellum
BDT_RS02640	COG1575	Belongs to the MenA family. Type 1 subfamily
BDT_RS02650	COG0318	PFAM AMP-dependent synthetase and ligase
BDT_RS02680	COG0824	Thioesterase
BDT_RS02685	COG0142	geranyltranstransferase activity
BDT_RS02695	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BDT_RS02710	COG0372	Belongs to the citrate synthase family
BDT_RS02740	COG0537	adenosine 5'-monophosphoramidase activity
BDT_RS02755	COG2070	2-Nitropropane dioxygenase
BDT_RS02775	COG0643	Histidine kinase
BDT_RS02775	COG2198	Histidine kinase
BDT_RS02780	COG0835	chemotaxis
BDT_RS02785	COG2201	protein-glutamate methylesterase activity
BDT_RS02805	COG2205	protein histidine kinase activity
BDT_RS02805	COG0784	Response regulator, receiver
BDT_RS02805	COG5002	protein histidine kinase activity
BDT_RS02810	COG1181	Belongs to the D-alanine--D-alanine ligase family
BDT_RS02815	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
BDT_RS02835	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BDT_RS02855	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BDT_RS02860	COG0784	Response regulator, receiver
BDT_RS02860	COG2205	protein histidine kinase activity
BDT_RS02885	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BDT_RS02895	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BDT_RS02905	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BDT_RS02920	COG1516	flagellar protein fliS
BDT_RS02945	COG0859	PFAM glycosyl transferase family 9
BDT_RS02965	COG0742	ribosomal rna small subunit methyltransferase
BDT_RS02970	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BDT_RS02975	COG0436	Aminotransferase
BDT_RS02995	COG5640	endopeptidase activity
BDT_RS03010	COG2885	chlorophyll binding
BDT_RS03025	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BDT_RS03030	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BDT_RS03035	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BDT_RS03060	COG2933	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA methyltransferase RlmE family. RlmM subfamily
BDT_RS03075	COG1846	Transcriptional regulator
BDT_RS03090	COG0024	Methionine aminopeptidase
BDT_RS03095	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BDT_RS03095	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BDT_RS03105	COG0494	nUDIX hydrolase
BDT_RS03115	COG1272	protein, Hemolysin III
BDT_RS03235	COG0484	heat shock protein binding
BDT_RS03270	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BDT_RS03305	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BDT_RS03305	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BDT_RS03310	COG2814	Major facilitator Superfamily
BDT_RS03340	COG0312	modulator of DNA gyrase
BDT_RS03345	COG0312	modulator of DNA gyrase
BDT_RS03355	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BDT_RS03380	COG0577	efflux transmembrane transporter activity
BDT_RS03380	COG1136	(ABC) transporter
BDT_RS03390	COG0776	regulation of translation
BDT_RS03405	COG0494	nUDIX hydrolase
BDT_RS03410	COG0167	dihydroorotate dehydrogenase activity
BDT_RS03415	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BDT_RS03430	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BDT_RS03430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BDT_RS03440	COG1047	Peptidyl-prolyl cis-trans
BDT_RS03470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BDT_RS03490	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BDT_RS03525	COG0166	Belongs to the GPI family
BDT_RS03600	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BDT_RS03620	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BDT_RS03640	COG0321	lipoyl(octanoyl) transferase activity
BDT_RS03660	COG2365	Tyrosine phosphatase family
BDT_RS03690	COG0508	dehydrogenase complex catalyzes the overall conversion of
BDT_RS03695	COG1489	DNA binding
BDT_RS03700	COG1064	alcohol dehydrogenase
BDT_RS03725	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BDT_RS03725	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BDT_RS03755	COG0148	phosphopyruvate hydratase activity
BDT_RS03780	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BDT_RS03780	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BDT_RS03795	COG2204	response regulator
BDT_RS03800	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BDT_RS03805	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BDT_RS03810	COG0504	CTP synthase activity
BDT_RS03815	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BDT_RS03815	COG0517	IMP dehydrogenase activity
BDT_RS03825	COG3708	Transcriptional regulator
BDT_RS03830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BDT_RS03895	COG1126	abc transporter atp-binding protein
BDT_RS03900	COG0765	amino acid transport
BDT_RS03915	COG1778	Involved in the biosynthesis of lipopolysaccharides (LPSs). Catalyzes the hydrolysis of 3-deoxy-D-manno-octulosonate 8-phosphate (KDO 8-P) to 3-deoxy-D-manno-octulosonate (KDO) and inorganic phosphate
BDT_RS03955	COG0811	peptide transport
BDT_RS03980	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BDT_RS03990	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BDT_RS04015	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BDT_RS04020	COG0481	GTPase activity
BDT_RS04025	COG0681	Belongs to the peptidase S26 family
BDT_RS04035	COG0681	Belongs to the peptidase S26 family
BDT_RS04040	COG0540	Belongs to the ATCase OTCase family
BDT_RS04045	COG0505	Belongs to the CarA family
BDT_RS04055	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BDT_RS04065	COG1131	(ABC) transporter
BDT_RS04075	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BDT_RS04120	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BDT_RS04160	COG2267	carboxylic ester hydrolase activity
BDT_RS04185	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BDT_RS04205	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BDT_RS04205	COG2885	chlorophyll binding
BDT_RS04235	COG2154	pterin-4-alpha-carbinolamine dehydratase
BDT_RS04260	COG1028	Short-chain dehydrogenase reductase Sdr
BDT_RS04280	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BDT_RS04285	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BDT_RS04300	COG0583	DNA-binding transcription factor activity
BDT_RS04325	COG0583	DNA-binding transcription factor activity
BDT_RS04335	COG0596	Alpha beta hydrolase
BDT_RS04350	COG0826	peptidase U32
BDT_RS04360	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BDT_RS04370	COG0039	L-malate dehydrogenase activity
BDT_RS04385	COG2356	endonuclease I
BDT_RS04420	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BDT_RS04425	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BDT_RS04430	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BDT_RS04440	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BDT_RS04450	COG0644	oxidoreductase
BDT_RS04450	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BDT_RS04455	COG0116	Belongs to the methyltransferase superfamily
BDT_RS04475	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BDT_RS04485	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BDT_RS04490	COG2183	response to ionizing radiation
BDT_RS04505	COG0312	modulator of DNA gyrase
BDT_RS04510	COG0312	modulator of DNA gyrase
BDT_RS04530	COG0561	phosphatase activity
BDT_RS04535	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BDT_RS04545	COG0793	Belongs to the peptidase S41A family
BDT_RS04565	COG0022	dehydrogenase e1 component
BDT_RS04595	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BDT_RS04600	COG1324	tolerance protein
BDT_RS04605	COG1253	flavin adenine dinucleotide binding
BDT_RS04630	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BDT_RS04635	COG0514	ATP-dependent DNA helicase (RecQ)
BDT_RS04645	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BDT_RS04665	COG3591	Belongs to the peptidase S1B family
BDT_RS04670	COG0488	(ABC) transporter
BDT_RS04715	COG3384	dioxygenase
BDT_RS04725	COG0583	DNA-binding transcription factor activity
BDT_RS04735	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BDT_RS04740	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BDT_RS04745	COG2062	phosphohistidine phosphatase, SixA
BDT_RS04760	COG0248	Ppx GppA phosphatase
BDT_RS04770	COG0704	Plays a role in the regulation of phosphate uptake
BDT_RS04775	COG0745	RESPONSE REGULATOR receiver
BDT_RS04780	COG5002	protein histidine kinase activity
BDT_RS04830	COG4106	trans-aconitate 2-methyltransferase activity
BDT_RS04835	COG0598	Magnesium transport protein CorA
BDT_RS04840	COG1073	alpha beta
BDT_RS04875	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BDT_RS04880	COG0470	DNA polymerase III
BDT_RS04885	COG0084	hydrolase, TatD family'
BDT_RS04920	COG0126	phosphoglycerate kinase activity
BDT_RS04925	COG0149	triose-phosphate isomerase activity
BDT_RS04940	COG0017	Asparaginyl-tRNA synthetase
BDT_RS04945	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BDT_RS04955	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BDT_RS04970	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BDT_RS04975	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BDT_RS05000	COG0616	signal peptide processing
BDT_RS05030	COG1840	ABC-type Fe3 transport system, periplasmic component
BDT_RS05035	COG2031	fatty acid transporter
BDT_RS05045	COG1580	Controls the rotational direction of flagella during chemotaxis
BDT_RS05050	COG0612	Peptidase, M16
BDT_RS05065	COG0583	DNA-binding transcription factor activity
BDT_RS05070	COG0840	transmembrane signaling receptor activity
BDT_RS05090	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BDT_RS05105	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BDT_RS05110	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BDT_RS05120	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BDT_RS05120	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BDT_RS05140	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BDT_RS05160	COG0124	histidyl-tRNA synthetase
BDT_RS05175	COG4181	ATPase activity
BDT_RS05245	COG0741	lytic transglycosylase activity
BDT_RS05245	COG1388	LysM domain
BDT_RS05255	COG0583	DNA-binding transcription factor activity
BDT_RS05280	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BDT_RS05360	COG1028	Short-chain dehydrogenase reductase Sdr
BDT_RS05380	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BDT_RS05380	COG0515	serine threonine protein kinase
BDT_RS05405	COG1028	Short-chain dehydrogenase reductase Sdr
BDT_RS05630	COG4191	Histidine kinase
BDT_RS05630	COG0784	Response regulator, receiver
BDT_RS05655	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BDT_RS05695	COG0489	protein tyrosine kinase activity
BDT_RS05725	COG2832	Protein of unknown function (DUF454)
BDT_RS05740	COG0423	glycine-tRNA ligase activity
BDT_RS05755	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BDT_RS05755	COG0574	Belongs to the PEP-utilizing enzyme family
BDT_RS05760	COG3008	intermembrane lipid transfer
BDT_RS05765	COG2995	paraquat-inducible protein a
BDT_RS05770	COG0753	catalase activity
BDT_RS05785	COG1196	nuclear chromosome segregation
BDT_RS05805	COG0778	Nitroreductase
BDT_RS05810	COG1959	2 iron, 2 sulfur cluster binding
BDT_RS05845	COG0702	epimerase
BDT_RS05870	COG2989	Protein conserved in bacteria
BDT_RS05885	COG3027	Activator of cell division through the inhibition of FtsZ GTPase activity, therefore promoting FtsZ assembly into bundles of protofilaments necessary for the formation of the division Z ring. It is recruited early at mid-cell but it is not essential for cell division
BDT_RS05890	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BDT_RS05895	COG1418	mRNA catabolic process
BDT_RS05900	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BDT_RS05910	COG0596	Alpha beta hydrolase
BDT_RS05920	COG0316	Belongs to the HesB IscA family
BDT_RS05925	COG1104	cysteine desulfurase activity
BDT_RS05935	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BDT_RS05940	COG0539	negative regulation of cytoplasmic translation
BDT_RS05950	COG1058	Belongs to the CinA family
BDT_RS05950	COG1546	Belongs to the CinA family
BDT_RS05955	COG1960	acyl-CoA dehydrogenase activity
BDT_RS05965	COG5599	Phosphatase
BDT_RS05975	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BDT_RS05975	COG0116	Belongs to the methyltransferase superfamily
BDT_RS05980	COG1704	LemA family
BDT_RS05985	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BDT_RS06090	COG0583	DNA-binding transcription factor activity
BDT_RS06095	COG2814	Major facilitator Superfamily
BDT_RS06155	COG1940	carbohydrate kinase activity
BDT_RS06165	COG3842	ATPase activity
BDT_RS06170	COG3833	ABC-type maltose transport systems, permease component
BDT_RS06175	COG1175	transmembrane transport
BDT_RS06185	COG4580	involved in the transport of maltose and maltodextrins
BDT_RS06195	COG1741	Belongs to the pirin family
BDT_RS06200	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BDT_RS06215	COG0783	Belongs to the Dps family
BDT_RS06250	COG2356	endonuclease I
BDT_RS06270	COG1012	belongs to the aldehyde dehydrogenase family
BDT_RS06275	COG0179	Fumarylacetoacetate (FAA) hydrolase
BDT_RS06285	COG1281	Redox regulated molecular chaperone. Protects both thermally unfolding and oxidatively damaged proteins from irreversible aggregation. Plays an important role in the bacterial defense system toward oxidative stress
BDT_RS06290	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BDT_RS06295	COG2205	protein histidine kinase activity
BDT_RS06320	COG0473	3-isopropylmalate dehydrogenase activity
BDT_RS06380	COG1193	negative regulation of DNA recombination
BDT_RS06385	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BDT_RS06405	COG1404	Belongs to the peptidase S8 family
BDT_RS06435	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BDT_RS06440	COG4968	Prepilin-type N-terminal cleavage methylation domain
BDT_RS06485	COG0484	heat shock protein binding
BDT_RS06490	COG0443	Heat shock 70 kDa protein
BDT_RS06510	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BDT_RS06550	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BDT_RS06560	COG3012	SEC-C Motif Domain Protein
BDT_RS06565	COG4221	oxidoreductase activity
BDT_RS06595	COG0564	pseudouridine synthase activity
BDT_RS06620	COG0271	Belongs to the BolA IbaG family
BDT_RS06630	COG0488	(ABC) transporter
BDT_RS06660	COG0024	Methionine aminopeptidase
BDT_RS06665	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BDT_RS06670	COG0840	transmembrane signaling receptor activity
BDT_RS06680	COG4335	DNA alkylation repair
BDT_RS06690	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BDT_RS06695	COG0745	RESPONSE REGULATOR receiver
BDT_RS06725	COG0427	acetyl-CoA hydrolase
BDT_RS06770	COG1404	Belongs to the peptidase S8 family
BDT_RS06780	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BDT_RS06780	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BDT_RS06805	COG3191	aminopeptidase activity
BDT_RS06815	COG0513	Belongs to the DEAD box helicase family
BDT_RS06825	COG0006	proline dipeptidase activity
BDT_RS06870	COG3850	Histidine kinase
BDT_RS06870	COG2205	protein histidine kinase activity
BDT_RS06870	COG4999	Histidine kinase
BDT_RS06870	COG3437	response regulator, receiver
BDT_RS06880	COG0564	pseudouridine synthase activity
BDT_RS06945	COG0513	Belongs to the DEAD box helicase family
BDT_RS06950	COG2996	Protein conserved in bacteria
BDT_RS06955	COG0724	RNA recognition motif
BDT_RS06975	COG2032	superoxide dismutase activity
BDT_RS07030	COG0513	Belongs to the DEAD box helicase family
BDT_RS07040	COG0488	(ABC) transporter
BDT_RS07055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BDT_RS07060	COG3842	ATPase activity
BDT_RS07070	COG1177	transmembrane transport
BDT_RS07075	COG2270	Major facilitator Superfamily
BDT_RS07080	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BDT_RS07085	COG0564	pseudouridine synthase activity
BDT_RS07090	COG1846	Transcriptional regulator
BDT_RS07095	COG1418	mRNA catabolic process
BDT_RS07120	COG1404	Belongs to the peptidase S8 family
BDT_RS07135	COG1764	response to oxidative stress
BDT_RS07140	COG2855	membrane
BDT_RS07180	COG1404	Belongs to the peptidase S8 family
BDT_RS07210	COG3119	arylsulfatase activity
BDT_RS07215	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BDT_RS07235	COG0583	DNA-binding transcription factor activity
BDT_RS07250	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BDT_RS07355	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BDT_RS07360	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BDT_RS07365	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BDT_RS07385	COG0268	Binds directly to 16S ribosomal RNA
BDT_RS07390	COG0728	peptidoglycan biosynthetic process
BDT_RS07395	COG0840	transmembrane signaling receptor activity
BDT_RS07400	COG0840	transmembrane signaling receptor activity
BDT_RS07445	COG0811	peptide transport
BDT_RS07460	COG3956	TIGRFAM MazG family protein
BDT_RS07470	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BDT_RS07475	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BDT_RS07480	COG1136	(ABC) transporter
BDT_RS07480	COG0577	efflux transmembrane transporter activity
BDT_RS07485	COG1136	(ABC) transporter
BDT_RS07490	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BDT_RS07500	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BDT_RS07510	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BDT_RS07515	COG1663	tetraacyldisaccharide 4'-kinase activity
BDT_RS07520	COG1560	Kdo2-lipid A biosynthetic process
BDT_RS07545	COG2204	response regulator
BDT_RS07550	COG2205	protein histidine kinase activity
BDT_RS07565	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BDT_RS07575	COG1459	type II secretion system
BDT_RS07580	COG3852	Histidine kinase
BDT_RS07585	COG2204	response regulator
BDT_RS07600	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BDT_RS07620	COG0564	pseudouridine synthase activity
BDT_RS07635	COG2204	response regulator
BDT_RS07665	COG1132	(ABC) transporter
BDT_RS07670	COG0572	uridine kinase
BDT_RS07675	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BDT_RS07690	COG1012	belongs to the aldehyde dehydrogenase family
BDT_RS07695	COG0784	Response regulator, receiver
BDT_RS07695	COG2205	protein histidine kinase activity
BDT_RS07765	COG0779	Required for maturation of 30S ribosomal subunits
BDT_RS07770	COG0195	Participates in both transcription termination and antitermination
BDT_RS07775	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BDT_RS07780	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BDT_RS07785	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BDT_RS07790	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BDT_RS07795	COG1185	polyribonucleotide nucleotidyltransferase activity
BDT_RS07800	COG0612	Peptidase, M16
BDT_RS07805	COG0756	dUTP diphosphatase activity
BDT_RS07840	COG1216	Glycosyl transferase, family 2
BDT_RS07855	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BDT_RS07860	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BDT_RS07865	COG1561	YicC-like family, N-terminal region
BDT_RS07870	COG0194	GDP metabolic process
BDT_RS07875	COG1758	RNA polymerase activity
BDT_RS07885	COG0784	Response regulator, receiver
BDT_RS07885	COG4191	Histidine kinase
BDT_RS07910	COG4264	IucA IucC family
BDT_RS08010	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BDT_RS08030	COG0840	transmembrane signaling receptor activity
BDT_RS08045	COG2096	Adenosyltransferase
BDT_RS08060	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BDT_RS08060	COG1333	cytochrome c biogenesis protein
BDT_RS08115	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BDT_RS08120	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BDT_RS08125	COG1490	D-aminoacyl-tRNA deacylase activity
BDT_RS08140	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BDT_RS08145	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BDT_RS08150	COG1304	FMN binding
BDT_RS08180	COG0357	Ribosomal RNA small subunit methyltransferase G
BDT_RS08180	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BDT_RS08195	COG0357	Ribosomal RNA small subunit methyltransferase G
BDT_RS08200	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BDT_RS08205	COG0072	phenylalanine-tRNA ligase activity
BDT_RS08205	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BDT_RS08210	COG0776	regulation of translation
BDT_RS08255	COG0628	permease
BDT_RS08285	COG0735	belongs to the Fur family
BDT_RS08295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BDT_RS08300	COG0573	inorganic phosphate transmembrane transporter activity
BDT_RS08305	COG0581	inorganic phosphate transmembrane transporter activity
BDT_RS08310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BDT_RS08380	COG1368	sulfuric ester hydrolase activity
BDT_RS08390	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BDT_RS08390	COG2755	lipolytic protein G-D-S-L family
BDT_RS08405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BDT_RS08410	COG0463	Glycosyl transferase, family 2
BDT_RS08465	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BDT_RS08465	COG0519	Catalyzes the synthesis of GMP from XMP
BDT_RS08470	COG0482	sulfurtransferase activity
BDT_RS08485	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BDT_RS08490	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BDT_RS08530	COG3550	peptidyl-serine autophosphorylation
BDT_RS08550	COG2070	2-Nitropropane dioxygenase
BDT_RS08565	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BDT_RS08575	COG3021	interspecies interaction between organisms
BDT_RS08585	COG3744	PilT protein domain protein
BDT_RS08605	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BDT_RS08620	COG3932	Exopolysaccharide synthesis, ExoD
BDT_RS08635	COG1720	tRNA m6t6A37 methyltransferase activity
BDT_RS08645	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BDT_RS08645	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BDT_RS08660	COG1077	Cell shape determining protein MreB Mrl
BDT_RS08710	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BDT_RS08715	COG2323	membrane
BDT_RS08750	COG2076	Multidrug Resistance protein
BDT_RS08760	COG0431	NADPH-dependent FMN reductase
BDT_RS08795	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BDT_RS08800	COG2884	Cell division ATP-binding protein ftsE
BDT_RS08825	COG2171	N-acyltransferase activity
BDT_RS08835	COG0019	diaminopimelate decarboxylase activity
BDT_RS08840	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BDT_RS08845	COG0516	GMP reductase activity
BDT_RS08845	COG0517	IMP dehydrogenase activity
BDT_RS08950	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BDT_RS08965	COG0318	PFAM AMP-dependent synthetase and ligase
BDT_RS08975	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BDT_RS08980	COG0326	Molecular chaperone. Has ATPase activity
BDT_RS08985	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BDT_RS08995	COG3483	tryptophan 2,3-dioxygenase activity
BDT_RS09025	COG0038	chloride channel
BDT_RS09040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BDT_RS09045	COG0617	tRNA 3'-terminal CCA addition
BDT_RS09070	COG2197	response regulator
BDT_RS09080	COG0784	Response regulator, receiver
BDT_RS09080	COG2205	protein histidine kinase activity
BDT_RS09095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BDT_RS09105	COG0281	malic enzyme
BDT_RS09105	COG0280	phosphate acetyltransferase
BDT_RS09115	COG1250	3-hydroxyacyl-CoA dehydrogenase
BDT_RS09115	COG1024	Enoyl-CoA hydratase
BDT_RS09120	COG2072	flavoprotein involved in K transport
BDT_RS09135	COG3104	oligopeptide transport
BDT_RS09175	COG1250	3-hydroxyacyl-CoA dehydrogenase
BDT_RS09180	COG1024	Enoyl-CoA hydratase
BDT_RS09185	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BDT_RS09185	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BDT_RS09185	COG1703	isobutyryl-CoA mutase activity
BDT_RS09190	COG2205	protein histidine kinase activity
BDT_RS09200	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
BDT_RS09205	COG0688	phosphatidylethanolamine metabolic process
BDT_RS09220	COG0720	synthase
BDT_RS09250	COG1088	dTDP-glucose 4,6-dehydratase activity
BDT_RS09255	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BDT_RS09260	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BDT_RS09265	COG0840	transmembrane signaling receptor activity
BDT_RS09275	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BDT_RS09280	COG1131	(ABC) transporter
BDT_RS09285	COG1131	(ABC) transporter
BDT_RS09290	COG0842	Transport permease protein
BDT_RS09295	COG0842	Transport permease protein
BDT_RS09330	COG0471	metal ion transport
BDT_RS09405	COG1073	alpha beta
BDT_RS09470	COG0531	amino acid
BDT_RS09485	COG0590	tRNA wobble adenosine to inosine editing
BDT_RS09505	COG2814	Major facilitator Superfamily
BDT_RS09510	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BDT_RS09515	COG0824	Thioesterase
BDT_RS09555	COG1012	belongs to the aldehyde dehydrogenase family
BDT_RS09560	COG0037	tRNA processing
BDT_RS09565	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BDT_RS09570	COG1624	Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria
BDT_RS09580	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BDT_RS09585	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BDT_RS09590	COG0802	atpase or kinase
BDT_RS09620	COG0482	sulfurtransferase activity
BDT_RS09625	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BDT_RS09630	COG0571	ribonuclease III activity
BDT_RS09635	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BDT_RS09640	COG1160	GTP binding
BDT_RS09645	COG0733	neurotransmitter:sodium symporter activity
BDT_RS09655	COG0386	Belongs to the glutathione peroxidase family
BDT_RS09665	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BDT_RS09675	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BDT_RS09680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BDT_RS09685	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BDT_RS09720	COG2166	iron-sulfur cluster assembly
BDT_RS09735	COG0217	transcriptional regulatory protein
BDT_RS09750	COG1187	pseudouridine synthase activity
BDT_RS09760	COG1028	Short-chain dehydrogenase reductase Sdr
BDT_RS09775	COG1716	ATPase activity
BDT_RS09775	COG5001	Diguanylate cyclase
BDT_RS09780	COG4166	transmembrane transport
BDT_RS09785	COG1960	acyl-CoA dehydrogenase activity
BDT_RS09790	COG1994	Peptidase M50
BDT_RS09795	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BDT_RS09800	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BDT_RS09830	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BDT_RS09835	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BDT_RS09835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BDT_RS09840	COG1242	4 iron, 4 sulfur cluster binding
BDT_RS09900	COG3158	transport of potassium into the cell
BDT_RS09915	COG3781	membrane
BDT_RS09935	COG4942	peptidase
BDT_RS09940	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BDT_RS09945	COG0698	ribose 5-phosphate isomerase
BDT_RS09950	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BDT_RS09955	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BDT_RS09960	COG1028	Short-chain dehydrogenase reductase Sdr
BDT_RS09970	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BDT_RS09975	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BDT_RS10005	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BDT_RS10010	COG1116	anion transmembrane transporter activity
BDT_RS10025	COG4974	Belongs to the 'phage' integrase family
BDT_RS10035	COG0018	arginyl-trna synthetase
BDT_RS10065	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BDT_RS10075	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BDT_RS10095	COG1011	Hydrolase
BDT_RS10105	COG1686	Belongs to the peptidase S11 family
BDT_RS10115	COG1837	Belongs to the UPF0109 family
BDT_RS10150	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BDT_RS10190	COG0037	tRNA processing
BDT_RS10200	COG0625	glutathione transferase activity
BDT_RS10240	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BDT_RS10270	COG0519	Catalyzes the synthesis of GMP from XMP
BDT_RS10270	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BDT_RS10275	COG0516	GMP reductase activity
BDT_RS10275	COG0517	IMP dehydrogenase activity
BDT_RS10280	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
BDT_RS10290	COG4651	solute:proton antiporter activity
BDT_RS10290	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BDT_RS10300	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BDT_RS10335	COG0183	Belongs to the thiolase family
BDT_RS10340	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BDT_RS10380	COG0776	regulation of translation
BDT_RS10395	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BDT_RS10415	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BDT_RS10430	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BDT_RS10435	COG0335	large ribosomal subunit rRNA binding
BDT_RS10440	COG4752	Belongs to the RNA methyltransferase TrmD family
BDT_RS10440	COG0336	Belongs to the RNA methyltransferase TrmD family
BDT_RS10445	COG0336	Belongs to the RNA methyltransferase TrmD family
BDT_RS10450	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BDT_RS10460	COG0228	four-way junction DNA binding
BDT_RS10465	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BDT_RS10485	COG0842	Transport permease protein
BDT_RS10490	COG1131	(ABC) transporter
BDT_RS10495	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BDT_RS10500	COG1054	Belongs to the UPF0176 family
BDT_RS10515	COG0387	Pfam Sodium calcium exchanger
BDT_RS10530	COG0328	RNA-DNA hybrid ribonuclease activity
BDT_RS10535	COG2197	response regulator
BDT_RS10540	COG2176	DNA-directed DNA polymerase activity
BDT_RS10555	COG0745	RESPONSE REGULATOR receiver
BDT_RS10560	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BDT_RS10565	COG3273	potassium ion transport
BDT_RS10565	COG0471	metal ion transport
BDT_RS10585	COG3237	CsbD-like
BDT_RS10620	COG0778	Nitroreductase
BDT_RS10645	COG2197	response regulator
BDT_RS10675	COG0730	response to heat
BDT_RS10685	COG2814	Major facilitator Superfamily
BDT_RS10700	COG1418	mRNA catabolic process
BDT_RS10705	COG0784	Response regulator, receiver
BDT_RS10705	COG2205	protein histidine kinase activity
BDT_RS10715	COG1253	flavin adenine dinucleotide binding
BDT_RS10720	COG2205	protein histidine kinase activity
BDT_RS10725	COG0745	RESPONSE REGULATOR receiver
BDT_RS10735	COG0038	chloride channel
BDT_RS10750	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BDT_RS10760	COG2205	protein histidine kinase activity
BDT_RS10775	COG0616	signal peptide processing
BDT_RS10780	COG0444	Belongs to the ABC transporter superfamily
BDT_RS10785	COG4608	Belongs to the ABC transporter superfamily
BDT_RS10790	COG4166	transmembrane transport
BDT_RS10795	COG0601	transmembrane transport
BDT_RS10800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BDT_RS10815	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BDT_RS10820	COG3239	Fatty acid desaturase
BDT_RS10835	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BDT_RS10850	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BDT_RS10855	COG1090	epimerase
BDT_RS10860	COG0415	Belongs to the DNA photolyase family
BDT_RS10865	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BDT_RS10870	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BDT_RS10900	COG1612	heme a metabolic process
BDT_RS10915	COG0494	nUDIX hydrolase
BDT_RS10935	COG2217	Heavy metal translocating P-type atpase
BDT_RS10940	COG1937	Protein conserved in bacteria
BDT_RS10970	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BDT_RS10980	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BDT_RS10985	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BDT_RS10990	COG1862	Preprotein translocase
BDT_RS10995	COG0343	queuine tRNA-ribosyltransferase activity
BDT_RS11000	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BDT_RS11015	COG0069	glutamate synthase activity
BDT_RS11035	COG1295	ribonuclease BN
BDT_RS11040	COG0723	plastoquinol--plastocyanin reductase activity
BDT_RS11040	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BDT_RS11070	COG0693	protein deglycase activity
BDT_RS11090	COG3665	Urea carboxylase-associated protein
BDT_RS11100	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BDT_RS11105	COG1720	tRNA m6t6A37 methyltransferase activity
BDT_RS11110	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BDT_RS11120	COG0288	reversible hydration of carbon dioxide
BDT_RS11135	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BDT_RS11160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BDT_RS11160	COG4651	solute:proton antiporter activity
BDT_RS11165	COG1404	Belongs to the peptidase S8 family
BDT_RS11170	COG0463	Glycosyl transferase, family 2
BDT_RS11210	COG0366	Alpha amylase catalytic
BDT_RS11225	COG1863	multisubunit Na H antiporter MnhE subunit
BDT_RS11230	COG0651	ATP synthesis coupled electron transport
BDT_RS11240	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BDT_RS11240	COG2111	Na H antiporter
BDT_RS11250	COG1011	Hydrolase
BDT_RS11260	COG1335	isochorismatase
BDT_RS11305	COG4974	Belongs to the 'phage' integrase family
BDT_RS11320	COG2385	sporulation resulting in formation of a cellular spore
BDT_RS11355	COG0728	peptidoglycan biosynthetic process
BDT_RS11360	COG0322	excinuclease ABC activity
BDT_RS11365	COG0556	nucleotide-excision repair
BDT_RS11385	COG0215	cysteine-tRNA ligase activity
BDT_RS11390	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BDT_RS11400	COG1404	Belongs to the peptidase S8 family
BDT_RS11415	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BDT_RS11450	COG1192	Involved in chromosome partitioning
BDT_RS11465	COG3591	Belongs to the peptidase S1B family
BDT_RS11470	COG2205	protein histidine kinase activity
BDT_RS11470	COG0784	Response regulator, receiver
BDT_RS11485	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BDT_RS11490	COG1830	Aldolase
BDT_RS11500	COG0534	Mate efflux family protein
BDT_RS11510	COG0477	Major facilitator Superfamily
BDT_RS11520	COG1671	Belongs to the UPF0178 family
BDT_RS11525	COG3217	Mosc domain protein beta barrel domain protein
BDT_RS11525	COG0633	Ferredoxin
BDT_RS11540	COG2226	methyltransferase
BDT_RS11555	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
BDT_RS11560	COG0084	hydrolase, TatD family'
BDT_RS11570	COG0586	Pfam SNARE associated Golgi protein
BDT_RS11610	COG0116	Belongs to the methyltransferase superfamily
BDT_RS11610	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
BDT_RS11630	COG0859	PFAM glycosyl transferase family 9
BDT_RS11690	COG0038	chloride channel
BDT_RS11750	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
BDT_RS11830	COG0745	RESPONSE REGULATOR receiver
BDT_RS11840	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BDT_RS11845	COG0717	Belongs to the dCTP deaminase family
BDT_RS11950	COG2871	sodium ion transport
BDT_RS11955	COG0697	spore germination
BDT_RS11965	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BDT_RS11985	COG1469	GTP cyclohydrolase I activity
BDT_RS11990	COG0424	maF-like protein
BDT_RS11995	COG0295	cytidine deaminase activity
BDT_RS12040	COG0768	penicillin binding
BDT_RS12045	COG0772	Belongs to the SEDS family
BDT_RS12080	COG3118	belongs to the thioredoxin family
BDT_RS12095	COG0758	DNA mediated transformation
BDT_RS12095	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BDT_RS12135	COG0686	Belongs to the AlaDH PNT family
BDT_RS12160	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
BDT_RS12175	COG2255	four-way junction helicase activity
BDT_RS12180	COG0632	four-way junction helicase activity
BDT_RS12185	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BDT_RS12195	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BDT_RS12210	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BDT_RS12240	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BDT_RS12245	COG0840	transmembrane signaling receptor activity
BDT_RS12250	COG0840	transmembrane signaling receptor activity
BDT_RS12260	COG0095	Lipoate-protein ligase
BDT_RS12320	COG3634	alkyl hydroperoxide reductase activity
BDT_RS12335	COG0308	aminopeptidase N
BDT_RS12340	COG0302	gtp cyclohydrolase
BDT_RS12400	COG3591	Belongs to the peptidase S1B family
BDT_RS12430	COG1132	(ABC) transporter
BDT_RS12435	COG1132	(ABC) transporter
BDT_RS12440	COG2239	Acts as a magnesium transporter
BDT_RS12480	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BDT_RS12490	COG2967	ApaG domain
BDT_RS12510	COG0259	pyridoxamine-phosphate oxidase activity
BDT_RS12515	COG0545	Peptidyl-prolyl cis-trans isomerase
BDT_RS12520	COG2603	Catalyzes the transfer of selenium from selenophosphate for conversion of 2-thiouridine to 2-selenouridine at the wobble position in tRNA
BDT_RS12525	COG0709	Synthesizes selenophosphate from selenide and ATP
BDT_RS12530	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BDT_RS12545	COG0745	RESPONSE REGULATOR receiver
BDT_RS12550	COG2205	protein histidine kinase activity
BDT_RS12575	COG0673	inositol 2-dehydrogenase activity
BDT_RS12580	COG1132	(ABC) transporter
BDT_RS12585	COG4999	Histidine kinase
BDT_RS12585	COG3850	Histidine kinase
BDT_RS12585	COG3437	response regulator, receiver
BDT_RS12585	COG2205	protein histidine kinase activity
BDT_RS12615	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BDT_RS12660	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BDT_RS12680	COG3278	Belongs to the heme-copper respiratory oxidase family
BDT_RS12685	COG2010	Cytochrome c
BDT_RS12690	COG0348	domain, Protein
BDT_RS12710	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BDT_RS12720	COG0783	Belongs to the Dps family
BDT_RS12730	COG0786	glutamate:sodium symporter activity
BDT_RS12750	COG3591	Belongs to the peptidase S1B family
BDT_RS12770	COG2272	Belongs to the type-B carboxylesterase lipase family
BDT_RS12795	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BDT_RS12800	COG3608	succinylglutamate desuccinylase aspartoacylase
BDT_RS12800	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BDT_RS12805	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
BDT_RS12815	COG2346	COG2346, Truncated hemoglobins
BDT_RS12875	COG2824	Alkylphosphonate utilization operon protein PhnA
BDT_RS12880	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BDT_RS12885	COG1215	transferase activity, transferring glycosyl groups
BDT_RS12895	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BDT_RS12960	COG0784	Response regulator, receiver
BDT_RS12960	COG2205	protein histidine kinase activity
BDT_RS12960	COG5002	protein histidine kinase activity
BDT_RS12980	COG0625	glutathione transferase activity
BDT_RS13015	COG3214	Protein conserved in bacteria
BDT_RS13090	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BDT_RS13105	COG1024	Enoyl-CoA hydratase
BDT_RS13115	COG1968	undecaprenyl-diphosphatase activity
BDT_RS13120	COG0668	transmembrane transport
BDT_RS13145	COG0860	N-Acetylmuramoyl-L-alanine amidase
BDT_RS13150	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BDT_RS13155	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BDT_RS13165	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BDT_RS13170	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BDT_RS13175	COG0193	aminoacyl-tRNA hydrolase activity
BDT_RS13180	COG0012	GTP binding
BDT_RS13185	COG0154	amidase activity
BDT_RS13190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BDT_RS13195	COG0601	transmembrane transport
BDT_RS13205	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BDT_RS13210	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BDT_RS13230	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BDT_RS13250	COG1228	amidohydrolase
BDT_RS13255	COG0071	Belongs to the small heat shock protein (HSP20) family
BDT_RS13280	COG0588	phosphoglycerate mutase activity
BDT_RS13285	COG0567	Dehydrogenase, E1 component
BDT_RS13290	COG0508	dehydrogenase complex catalyzes the overall conversion of
BDT_RS13370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BDT_RS13380	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BDT_RS13395	COG0494	nUDIX hydrolase
BDT_RS13400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BDT_RS13405	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BDT_RS13410	COG0242	peptide deformylase activity
BDT_RS13465	COG0588	phosphoglycerate mutase activity
BDT_RS13470	COG1132	(ABC) transporter
BDT_RS13505	COG1136	(ABC) transporter
BDT_RS13505	COG0577	efflux transmembrane transporter activity
BDT_RS13535	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BDT_RS13550	COG2072	flavoprotein involved in K transport
BDT_RS13575	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BDT_RS13580	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BDT_RS13635	COG2304	oxidoreductase activity
BDT_RS13655	COG0714	Associated with various cellular activities
BDT_RS13660	COG0501	Belongs to the peptidase M48B family
BDT_RS13670	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BDT_RS13675	COG2088	sporulation resulting in formation of a cellular spore
BDT_RS13705	COG1309	transcriptional regulator
BDT_RS13740	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BDT_RS13745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BDT_RS13785	COG0745	RESPONSE REGULATOR receiver
BDT_RS13795	COG3096	Plays a central role in chromosome condensation, segregation and cell cycle progression. Functions as a homodimer, which is essential for chromosome partition. Involved in negative DNA supercoiling in vivo, and by this means organize and compact chromosomes. May achieve or facilitate chromosome segregation by condensation DNA from both sides of a centrally located replisome during cell division
BDT_RS13795	COG3264	Mechanosensitive ion channel
BDT_RS13820	COG0564	pseudouridine synthase activity
BDT_RS13845	COG3005	denitrification pathway
BDT_RS13850	COG3303	Catalyzes the reduction of nitrite to ammonia, consuming six electrons in the process
BDT_RS13875	COG0835	chemotaxis
BDT_RS13880	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BDT_RS13885	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BDT_RS13905	COG0784	Response regulator, receiver
BDT_RS13905	COG2205	protein histidine kinase activity
BDT_RS13910	COG0281	malic enzyme
BDT_RS13925	COG2353	YceI-like domain
BDT_RS13930	COG2197	response regulator
BDT_RS13935	COG2205	protein histidine kinase activity
BDT_RS13955	COG0477	Major facilitator Superfamily
BDT_RS13960	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BDT_RS13960	COG2205	protein histidine kinase activity
BDT_RS13965	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BDT_RS13985	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BDT_RS13995	COG5002	protein histidine kinase activity
BDT_RS13995	COG0784	Response regulator, receiver
BDT_RS14015	COG1690	Belongs to the RtcB family
BDT_RS14035	COG1027	Aspartate ammonia-lyase
BDT_RS14055	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BDT_RS14155	COG1368	sulfuric ester hydrolase activity
BDT_RS14165	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BDT_RS14175	COG0277	FAD linked oxidase domain protein
BDT_RS14185	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BDT_RS14205	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BDT_RS14210	COG1295	ribonuclease BN
BDT_RS14230	COG0583	DNA-binding transcription factor activity
BDT_RS14235	COG1073	alpha beta
BDT_RS14240	COG4221	oxidoreductase activity
BDT_RS14250	COG2195	Cleaves the N-terminal amino acid of tripeptides
BDT_RS14310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BDT_RS14345	COG2942	2-epimerase
BDT_RS14355	COG0519	Catalyzes the synthesis of GMP from XMP
BDT_RS14355	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BDT_RS14370	COG1960	acyl-CoA dehydrogenase activity
BDT_RS14450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BDT_RS14470	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BDT_RS14475	COG0203	ribosomal protein L17
BDT_RS14480	COG0202	RNA polymerase activity
BDT_RS14485	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BDT_RS14490	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BDT_RS14495	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BDT_RS14500	COG0563	adenylate kinase activity
BDT_RS14505	COG0201	protein transport
BDT_RS14510	COG0200	Binds to the 23S rRNA
BDT_RS14515	COG1841	ribosomal large subunit assembly
BDT_RS14520	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BDT_RS14525	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BDT_RS14530	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BDT_RS14535	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BDT_RS14540	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BDT_RS14545	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BDT_RS14550	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BDT_RS14555	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BDT_RS14560	COG0255	Belongs to the universal ribosomal protein uL29 family
BDT_RS14565	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BDT_RS14570	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BDT_RS14575	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BDT_RS14580	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BDT_RS14585	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BDT_RS14590	COG0089	rRNA binding
BDT_RS14595	COG0088	Forms part of the polypeptide exit tunnel
BDT_RS14600	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BDT_RS14605	COG0051	transcription antitermination factor activity, RNA binding
BDT_RS14610	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BDT_RS14615	COG0049	tRNA binding
BDT_RS14620	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BDT_RS14625	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BDT_RS14630	COG0085	RNA polymerase activity
BDT_RS14640	COG0222	ribosome binding
BDT_RS14645	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BDT_RS14650	COG0081	regulation of translation
BDT_RS14655	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BDT_RS14660	COG0250	Participates in transcription elongation, termination and antitermination
BDT_RS14675	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BDT_RS14705	COG0284	orotidine-5'-phosphate decarboxylase activity
BDT_RS14715	COG0427	acetyl-CoA hydrolase
BDT_RS14735	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BDT_RS14740	COG0138	bifunctional purine biosynthesis protein purh
BDT_RS14745	COG0047	phosphoribosylformylglycinamidine synthase activity
BDT_RS14750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BDT_RS14755	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BDT_RS14760	COG0151	Belongs to the GarS family
BDT_RS14770	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BDT_RS14890	COG0442	prolyl-tRNA aminoacylation
BDT_RS14895	COG2204	response regulator
BDT_RS14900	COG5000	phosphorelay sensor kinase activity
BDT_RS14905	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BDT_RS14910	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BDT_RS14910	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BDT_RS14915	COG0307	riboflavin synthase, alpha
BDT_RS14940	COG1803	Methylglyoxal synthase
BDT_RS14945	COG0542	response to heat
BDT_RS14955	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BDT_RS14980	COG1846	Transcriptional regulator
BDT_RS15020	COG1381	Involved in DNA repair and RecF pathway recombination
BDT_RS15085	COG0583	DNA-binding transcription factor activity
BDT_RS15095	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BDT_RS15105	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BDT_RS15110	COG1034	ATP synthesis coupled electron transport
BDT_RS15120	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BDT_RS15125	COG0649	NAD binding
BDT_RS15125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BDT_RS15130	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BDT_RS15155	COG0840	transmembrane signaling receptor activity
BDT_RS15190	COG1132	(ABC) transporter
BDT_RS15195	COG1132	(ABC) transporter
BDT_RS15220	COG3639	organic phosphonate transmembrane transporter activity
BDT_RS15225	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BDT_RS15230	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
BDT_RS15245	COG1643	Atp-dependent helicase
BDT_RS15260	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BDT_RS15270	COG1045	serine acetyltransferase
BDT_RS15275	COG3481	metal-dependent phosphohydrolase, HD sub domain
BDT_RS15290	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BDT_RS15295	COG1127	ABC transporter
BDT_RS15300	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BDT_RS15305	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BDT_RS15315	COG3852	Histidine kinase
BDT_RS15335	COG0300	oxidoreductase activity
BDT_RS15340	COG0328	RNA-DNA hybrid ribonuclease activity
BDT_RS15395	COG1074	ATP-dependent DNA helicase activity
BDT_RS15435	COG0237	dephospho-CoA kinase activity
BDT_RS15440	COG0515	serine threonine protein kinase
BDT_RS15445	COG1022	Amp-dependent synthetase and ligase
BDT_RS15450	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BDT_RS15465	COG3848	Pyruvate phosphate dikinase
BDT_RS15465	COG0574	Belongs to the PEP-utilizing enzyme family
BDT_RS15515	COG4591	ABC-type transport system involved in lipoprotein release permease component
BDT_RS15520	COG0577	efflux transmembrane transporter activity
BDT_RS15520	COG1136	(ABC) transporter
BDT_RS15540	COG0339	signal peptide processing
BDT_RS15545	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BDT_RS15550	COG0497	DNA recombination
BDT_RS15570	COG0840	transmembrane signaling receptor activity
BDT_RS15615	COG2910	NAD(P)H-binding
BDT_RS15620	COG1959	2 iron, 2 sulfur cluster binding
BDT_RS15625	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
BDT_RS15640	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BDT_RS15645	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BDT_RS15655	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BDT_RS15660	COG0840	transmembrane signaling receptor activity
BDT_RS15680	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BDT_RS15685	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BDT_RS15690	COG0772	Belongs to the SEDS family
BDT_RS15700	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BDT_RS15705	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BDT_RS15710	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BDT_RS15715	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BDT_RS15720	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BDT_RS15750	COG0514	ATP-dependent DNA helicase (RecQ)
BDT_RS15760	COG0768	penicillin binding
BDT_RS15770	COG0275	rRNA processing
BDT_RS15780	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BDT_RS15795	COG2119	membrane
BDT_RS15815	COG1741	Belongs to the pirin family
BDT_RS15820	COG0583	DNA-binding transcription factor activity
BDT_RS15825	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BDT_RS15840	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BDT_RS15865	COG1404	Belongs to the peptidase S8 family
BDT_RS15880	COG0739	heme binding
BDT_RS15880	COG0741	lytic transglycosylase activity
BDT_RS15880	COG1196	nuclear chromosome segregation
BDT_RS15885	COG2027	D-alanyl-D-alanine carboxypeptidase
BDT_RS15890	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BDT_RS15905	COG3842	ATPase activity
BDT_RS15915	COG1840	ABC-type Fe3 transport system, periplasmic component
BDT_RS15920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BDT_RS15925	COG2176	DNA-directed DNA polymerase activity
BDT_RS15935	COG1360	Flagellar Motor Protein
BDT_RS15940	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BDT_RS15950	COG0840	transmembrane signaling receptor activity
BDT_RS15975	COG1187	pseudouridine synthase activity
BDT_RS16005	COG2264	protein methyltransferase activity
BDT_RS16010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BDT_RS16020	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BDT_RS16020	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BDT_RS16040	COG0726	polysaccharide deacetylase
BDT_RS16075	COG0443	Heat shock 70 kDa protein
BDT_RS16085	COG3384	dioxygenase
BDT_RS16090	COG0400	carboxylic ester hydrolase activity
BDT_RS16095	COG2814	Major facilitator Superfamily
BDT_RS16155	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BDT_RS16200	COG2204	response regulator
BDT_RS16205	COG4964	Belongs to the GSP D family
BDT_RS16230	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BDT_RS16240	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BDT_RS16250	COG1191	sigma factor activity
BDT_RS16270	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BDT_RS16275	COG1684	flagellar biosynthetic protein fliR
BDT_RS16280	COG1987	bacterial-type flagellum assembly
BDT_RS16285	COG1338	Plays a role in the flagellum-specific transport system
BDT_RS16310	COG3237	CsbD-like
BDT_RS16335	COG0483	inositol monophosphate 1-phosphatase activity
BDT_RS16355	COG0210	DNA helicase
BDT_RS16365	COG0840	transmembrane signaling receptor activity
BDT_RS16370	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BDT_RS16380	COG1509	lysine 2,3-aminomutase activity
BDT_RS16420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BDT_RS16460	COG5002	protein histidine kinase activity
BDT_RS16480	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BDT_RS16495	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BDT_RS16500	COG4191	Histidine kinase
BDT_RS16520	COG0803	Belongs to the bacterial solute-binding protein 9 family
BDT_RS16525	COG1121	(ABC) transporter
BDT_RS16560	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BDT_RS16570	COG0205	6-phosphofructokinase activity
BDT_RS16580	COG0559	Belongs to the binding-protein-dependent transport system permease family
BDT_RS16620	COG0745	RESPONSE REGULATOR receiver
BDT_RS16635	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BDT_RS16655	COG1157	protein secretion by the type III secretion system
BDT_RS16665	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BDT_RS16670	COG1766	The M ring may be actively involved in energy transduction
BDT_RS16675	COG1677	Flagellar hook-basal body complex protein FliE
BDT_RS16685	COG1815	bacterial-type flagellum-dependent cell motility
BDT_RS16690	COG2204	response regulator
BDT_RS16705	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BDT_RS16710	COG1127	ABC transporter
BDT_RS16745	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BDT_RS16750	COG1435	thymidine kinase activity
BDT_RS16755	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
BDT_RS16765	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BDT_RS16770	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BDT_RS16785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BDT_RS16785	COG4191	Histidine kinase
BDT_RS16795	COG0745	RESPONSE REGULATOR receiver
BDT_RS16800	COG2204	response regulator
BDT_RS16850	COG0113	porphobilinogen synthase activity
BDT_RS16860	COG0181	hydroxymethylbilane synthase activity
BDT_RS16865	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BDT_RS16875	COG0745	RESPONSE REGULATOR receiver
BDT_RS16880	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BDT_RS16885	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BDT_RS16895	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BDT_RS16900	COG1346	cytolysis
BDT_RS16905	COG1380	Effector of murein hydrolase LrgA
BDT_RS16920	COG0513	Belongs to the DEAD box helicase family
BDT_RS16925	COG0596	Alpha beta hydrolase
BDT_RS16925	COG2945	thiolester hydrolase activity
BDT_RS16930	COG0617	tRNA 3'-terminal CCA addition
BDT_RS16940	COG1505	serine-type exopeptidase activity
BDT_RS16950	COG2201	protein-glutamate methylesterase activity
BDT_RS16955	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BDT_RS16960	COG2198	Histidine kinase
BDT_RS16960	COG0643	Histidine kinase
BDT_RS16965	COG0835	chemotaxis
BDT_RS16980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BDT_RS16990	COG0405	Gamma-glutamyltransferase
BDT_RS17015	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BDT_RS17020	COG1169	isochorismate synthase
BDT_RS17025	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
BDT_RS17025	COG1605	Chorismate mutase
BDT_RS17030	COG2226	methyltransferase
BDT_RS17035	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BDT_RS17050	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BDT_RS17055	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BDT_RS17060	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BDT_RS17080	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
BDT_RS17090	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BDT_RS17095	COG0667	Aldo Keto reductase
BDT_RS17155	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BDT_RS17165	COG1741	Belongs to the pirin family
BDT_RS17175	COG1956	GAF domain-containing protein
BDT_RS17195	COG1309	transcriptional regulator
BDT_RS17210	COG0708	Exodeoxyribonuclease III
BDT_RS17215	COG0450	alkyl hydroperoxide reductase
BDT_RS17225	COG0745	RESPONSE REGULATOR receiver
BDT_RS17230	COG0784	Response regulator, receiver
BDT_RS17230	COG2198	Histidine kinase
BDT_RS17230	COG2205	protein histidine kinase activity
BDT_RS17255	COG0793	Belongs to the peptidase S41A family
BDT_RS17260	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BDT_RS17265	COG3186	Phenylalanine-4-hydroxylase
BDT_RS17310	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BDT_RS17345	COG1028	Short-chain dehydrogenase reductase Sdr
BDT_RS17365	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BDT_RS17370	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BDT_RS17380	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
BDT_RS17385	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BDT_RS17390	COG0488	(ABC) transporter
BDT_RS17405	COG0488	(ABC) transporter
BDT_RS17445	COG0439	Biotin carboxylase
BDT_RS17450	COG1024	Enoyl-CoA hydratase
BDT_RS17455	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BDT_RS17490	COG4555	ABC transporter
BDT_RS17600	COG0784	Response regulator, receiver
BDT_RS17600	COG5002	protein histidine kinase activity
BDT_RS17615	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
BDT_RS17655	COG0583	DNA-binding transcription factor activity
BDT_RS17660	COG2234	aminopeptidase activity
BDT_RS17675	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BDT_RS17730	COG0488	(ABC) transporter
BDT_RS17770	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BDT_RS17780	COG5002	protein histidine kinase activity
BDT_RS17785	COG0784	Response regulator, receiver
BDT_RS17790	COG0784	Response regulator, receiver
BDT_RS17790	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BDT_RS17790	COG2198	Histidine kinase
BDT_RS17790	COG2205	protein histidine kinase activity
BDT_RS17805	COG5507	3-demethylubiquinone-9 3-methyltransferase
BDT_RS17820	COG0656	L-ascorbic acid biosynthetic process
BDT_RS17825	COG2814	Major facilitator Superfamily
BDT_RS17880	COG0708	Exodeoxyribonuclease III
BDT_RS17910	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BDT_RS17915	COG1595	DNA-templated transcription, initiation
BDT_RS17920	COG0693	protein deglycase activity
BDT_RS17925	COG2205	protein histidine kinase activity
BDT_RS17925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BDT_RS17935	COG1061	Type III restriction enzyme res subunit
BDT_RS17940	COG2850	peptidyl-arginine hydroxylation
BDT_RS17945	COG1733	regulation of RNA biosynthetic process
BDT_RS17950	COG1741	Belongs to the pirin family
BDT_RS17955	COG1942	4-Oxalocrotonate Tautomerase
BDT_RS18005	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BDT_RS18040	COG2249	NAD(P)H dehydrogenase (quinone) activity
BDT_RS18055	COG0538	isocitrate dehydrogenase activity
BDT_RS18095	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BDT_RS18100	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BDT_RS18105	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BDT_RS18110	COG1100	Small GTP-binding protein
BDT_RS18115	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BDT_RS18165	COG3089	Belongs to the UPF0270 family
BDT_RS18190	COG3852	Histidine kinase
BDT_RS18200	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BDT_RS18205	COG0740	serine-type endopeptidase activity
BDT_RS18210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BDT_RS18240	COG0003	Pfam Anion-transporting ATPase
BDT_RS18250	COG0544	peptidyl-prolyl cis-trans isomerase activity
BDT_RS18275	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BDT_RS18285	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BDT_RS18305	COG0052	Belongs to the universal ribosomal protein uS2 family
BDT_RS18310	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BDT_RS18315	COG0528	UMP kinase activity
BDT_RS18320	COG0233	cytoplasmic translational termination
BDT_RS18325	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BDT_RS18330	COG4589	Belongs to the CDS family
BDT_RS18335	COG0750	zinc metalloprotease
BDT_RS18340	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BDT_RS18345	COG2894	cell division
BDT_RS18355	COG0564	pseudouridine synthase activity
BDT_RS18360	COG1496	oxidoreductase activity
BDT_RS18365	COG2094	Belongs to the DNA glycosylase MPG family
BDT_RS18370	COG1272	protein, Hemolysin III
BDT_RS18380	COG0626	cystathionine gamma-synthase activity
BDT_RS18420	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BDT_RS18425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BDT_RS18435	COG1127	ABC transporter
BDT_RS18450	COG1127	ABC transporter
BDT_RS18455	COG0045	succinate-CoA ligase (ADP-forming) activity
BDT_RS18460	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BDT_RS18500	COG0105	UTP biosynthetic process
BDT_RS18505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BDT_RS18515	COG1426	Protein conserved in bacteria
BDT_RS18530	COG0633	Ferredoxin
BDT_RS18535	COG2176	DNA-directed DNA polymerase activity
BDT_RS18540	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BDT_RS18540	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BDT_RS18560	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BDT_RS18565	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BDT_RS18580	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BDT_RS18590	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BDT_RS18595	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BDT_RS18600	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BDT_RS18625	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
BDT_RS18640	COG1404	Belongs to the peptidase S8 family
BDT_RS18645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BDT_RS18650	COG0439	Biotin carboxylase
BDT_RS18665	COG0805	protein transport
BDT_RS18685	COG0612	Peptidase, M16
BDT_RS18690	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BDT_RS18695	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BDT_RS18700	COG0484	heat shock protein binding
BDT_RS18720	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BDT_RS18760	COG0714	Associated with various cellular activities
BDT_RS18765	COG1007	ATP synthesis coupled electron transport
BDT_RS18780	COG0713	ATP synthesis coupled electron transport
BDT_RS18785	COG0839	Belongs to the complex I subunit 6 family
BDT_RS18790	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BDT_RS18795	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BDT_RS18815	COG1472	Belongs to the glycosyl hydrolase 3 family
BDT_RS18820	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BDT_RS18825	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BDT_RS18830	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BDT_RS18835	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BDT_RS18840	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BDT_RS18845	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BDT_RS18865	COG1192	Involved in chromosome partitioning
BDT_RS18875	COG0357	Ribosomal RNA small subunit methyltransferase G
BDT_RS18880	COG0445	tRNA wobble uridine modification
BDT_RS18885	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BDT_RS18895	COG0706	membrane insertase activity
BDT_RS18930	COG0583	DNA-binding transcription factor activity
BDT_RS18940	COG0840	transmembrane signaling receptor activity
BDT_RS18950	COG0840	transmembrane signaling receptor activity
BDT_RS18955	COG2204	response regulator
BDT_RS18975	COG2205	protein histidine kinase activity
BDT_RS18975	COG0784	Response regulator, receiver
BDT_RS18975	COG2198	Histidine kinase
BDT_RS18995	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter