locus-tag	class	description
AL038_RS00115	COG2356	endonuclease I
AL038_RS00120	COG4974	Belongs to the 'phage' integrase family
AL038_RS00260	COG3034	peptidoglycan biosynthetic process
AL038_RS00265	COG0315	cyclic pyranopterin monophosphate synthase activity
AL038_RS00275	COG0746	molybdenum cofactor guanylyltransferase activity
AL038_RS00295	COG1196	nuclear chromosome segregation
AL038_RS00305	COG0196	riboflavin kinase activity
AL038_RS00310	COG0728	peptidoglycan biosynthetic process
AL038_RS00315	COG0316	Belongs to the HesB IscA family
AL038_RS00335	COG4251	negative regulation of phosphorylation
AL038_RS00335	COG5001	Diguanylate cyclase
AL038_RS00335	COG3706	GGDEF domain
AL038_RS00335	COG2203	Gaf domain
AL038_RS00345	COG0519	Catalyzes the synthesis of GMP from XMP
AL038_RS00345	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL038_RS00380	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
AL038_RS00390	COG0812	UDP-N-acetylmuramate dehydrogenase activity
AL038_RS00395	COG1181	Belongs to the D-alanine--D-alanine ligase family
AL038_RS00400	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
AL038_RS00415	COG0774	UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity
AL038_RS00425	COG0653	protein targeting
AL038_RS00430	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
AL038_RS00450	COG1487	ribonuclease activity
AL038_RS00470	COG0129	dihydroxy-acid dehydratase activity
AL038_RS00505	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
AL038_RS00510	COG1850	ribulose-bisphosphate carboxylase activity
AL038_RS00515	COG4451	ribulose bisphosphate carboxylase, small
AL038_RS00520	COG1388	LysM domain
AL038_RS00520	COG0741	lytic transglycosylase activity
AL038_RS00530	COG2847	Copper chaperone PCu(A)C
AL038_RS00545	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
AL038_RS00560	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
AL038_RS00580	COG1859	Removes the 2'-phosphate from RNA via an intermediate in which the phosphate is ADP-ribosylated by NAD followed by a presumed transesterification to release the RNA and generate ADP- ribose 1''-2''-cyclic phosphate (APPR P). May function as an ADP- ribosylase
AL038_RS00585	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL038_RS00620	COG1690	Belongs to the RtcB family
AL038_RS00635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
AL038_RS00640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
AL038_RS00700	COG0004	ammonium transporteR
AL038_RS00720	COG3128	pkhd-type hydroxylase
AL038_RS00725	COG4774	siderophore transport
AL038_RS00735	COG1923	regulation of RNA biosynthetic process
AL038_RS00745	COG3885	ferrous iron binding
AL038_RS00745	COG2078	PFAM AMMECR1 domain protein
AL038_RS00750	COG1355	regulation of microtubule-based process
AL038_RS00780	COG2878	Part of a membrane complex involved in electron transport
AL038_RS00785	COG4656	Part of a membrane complex involved in electron transport
AL038_RS00800	COG4658	electron transport chain
AL038_RS00820	COG2319	Wd-40 repeat
AL038_RS00820	COG4249	Peptidase C14 caspase catalytic subunit p20
AL038_RS00845	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
AL038_RS00880	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL038_RS00895	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
AL038_RS00900	COG0230	Belongs to the bacterial ribosomal protein bL34 family
AL038_RS00905	COG0594	ribonuclease P activity
AL038_RS00910	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
AL038_RS00915	COG0706	membrane insertase activity
AL038_RS00930	COG1216	Glycosyl transferase, family 2
AL038_RS00930	COG0438	transferase activity, transferring glycosyl groups
AL038_RS00935	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
AL038_RS00940	COG0798	PFAM Bile acid sodium symporter
AL038_RS00945	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL038_RS00960	COG0521	Mo-molybdopterin cofactor biosynthetic process
AL038_RS00985	COG0736	holo-[acyl-carrier-protein] synthase activity
AL038_RS00990	COG0702	epimerase
AL038_RS01000	COG3252	Catalyzes the hydrolysis of methenyl-H(4)MPT( ) to 5- formyl-H(4)MPT
AL038_RS01010	COG1368	sulfuric ester hydrolase activity
AL038_RS01020	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL038_RS01035	COG0745	RESPONSE REGULATOR receiver
AL038_RS01050	COG2989	Protein conserved in bacteria
AL038_RS01055	COG3108	Peptidase M15
AL038_RS01105	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL038_RS01110	COG4999	Histidine kinase
AL038_RS01110	COG3850	Histidine kinase
AL038_RS01110	COG3437	response regulator, receiver
AL038_RS01110	COG2205	protein histidine kinase activity
AL038_RS01135	COG0730	response to heat
AL038_RS01140	COG0802	atpase or kinase
AL038_RS01175	COG1136	(ABC) transporter
AL038_RS01180	COG1136	(ABC) transporter
AL038_RS01180	COG0577	efflux transmembrane transporter activity
AL038_RS01185	COG0210	DNA helicase
AL038_RS01240	COG0445	tRNA wobble uridine modification
AL038_RS01295	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL038_RS01300	COG4569	acetaldehyde dehydrogenase (acetylating) activity
AL038_RS01375	COG4999	Histidine kinase
AL038_RS01375	COG3850	Histidine kinase
AL038_RS01375	COG2205	protein histidine kinase activity
AL038_RS01375	COG3437	response regulator, receiver
AL038_RS01405	COG2949	membrane
AL038_RS01410	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
AL038_RS01415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL038_RS01455	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL038_RS01515	COG3264	Mechanosensitive ion channel
AL038_RS01515	COG1196	nuclear chromosome segregation
AL038_RS01530	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL038_RS01535	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
AL038_RS01550	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
AL038_RS01555	COG0546	phosphoglycolate phosphatase activity
AL038_RS01570	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
AL038_RS01575	COG0259	pyridoxamine-phosphate oxidase activity
AL038_RS01595	COG2205	protein histidine kinase activity
AL038_RS01595	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS01605	COG2226	methyltransferase
AL038_RS01625	COG0840	transmembrane signaling receptor activity
AL038_RS01640	COG0842	Transport permease protein
AL038_RS01645	COG1131	(ABC) transporter
AL038_RS01650	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL038_RS01665	COG2198	Histidine kinase
AL038_RS01665	COG2205	protein histidine kinase activity
AL038_RS01665	COG0784	Response regulator, receiver
AL038_RS01665	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS01675	COG4172	Belongs to the ABC transporter superfamily
AL038_RS01680	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL038_RS01690	COG5002	protein histidine kinase activity
AL038_RS01690	COG0784	Response regulator, receiver
AL038_RS01690	COG2198	Histidine kinase
AL038_RS01695	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
AL038_RS01705	COG0784	Response regulator, receiver
AL038_RS01705	COG2205	protein histidine kinase activity
AL038_RS01730	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
AL038_RS01735	COG0571	ribonuclease III activity
AL038_RS01750	COG0481	GTPase activity
AL038_RS01760	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL038_RS01775	COG0189	ligase activity
AL038_RS01780	COG1773	rubredoxin
AL038_RS01810	COG0741	lytic transglycosylase activity
AL038_RS01825	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
AL038_RS01830	COG1132	(ABC) transporter
AL038_RS01845	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL038_RS01850	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
AL038_RS01855	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
AL038_RS01885	COG2239	Acts as a magnesium transporter
AL038_RS01910	COG0747	negative chemotaxis
AL038_RS01925	COG2192	nodulation
AL038_RS01940	COG0488	(ABC) transporter
AL038_RS01945	COG5002	protein histidine kinase activity
AL038_RS01945	COG2205	protein histidine kinase activity
AL038_RS01945	COG0784	Response regulator, receiver
AL038_RS01950	COG3852	Histidine kinase
AL038_RS01970	COG2205	protein histidine kinase activity
AL038_RS01970	COG0784	Response regulator, receiver
AL038_RS01970	COG2198	Histidine kinase
AL038_RS01975	COG3391	amine dehydrogenase activity
AL038_RS01985	COG2884	Cell division ATP-binding protein ftsE
AL038_RS01990	COG0142	geranyltranstransferase activity
AL038_RS01995	COG0529	Catalyzes the synthesis of activated sulfate
AL038_RS02010	COG2096	Adenosyltransferase
AL038_RS02020	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL038_RS02025	COG2119	membrane
AL038_RS02030	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
AL038_RS02040	COG0123	including yeast histone deacetylase and acetoin utilization protein
AL038_RS02050	COG3850	Histidine kinase
AL038_RS02080	COG1126	abc transporter atp-binding protein
AL038_RS02100	COG0310	cobalt ion transport
AL038_RS02105	COG0310	cobalt ion transport
AL038_RS02115	COG5001	Diguanylate cyclase
AL038_RS02115	COG5002	protein histidine kinase activity
AL038_RS02130	COG0436	Aminotransferase
AL038_RS02135	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
AL038_RS02145	COG3311	Transcriptional regulator
AL038_RS02150	COG0021	Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate
AL038_RS02160	COG2205	protein histidine kinase activity
AL038_RS02160	COG0784	Response regulator, receiver
AL038_RS02185	COG0475	glutathione-regulated potassium exporter activity
AL038_RS02220	COG3267	Type II secretory pathway component ExeA
AL038_RS02220	COG3409	Peptidoglycan-binding domain 1 protein
AL038_RS02225	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
AL038_RS02235	COG0742	ribosomal rna small subunit methyltransferase
AL038_RS02255	COG2885	chlorophyll binding
AL038_RS02260	COG0159	tryptophan synthase activity
AL038_RS02265	COG0133	tryptophan synthase activity
AL038_RS02270	COG1960	acyl-CoA dehydrogenase activity
AL038_RS02275	COG1960	acyl-CoA dehydrogenase activity
AL038_RS02305	COG2204	response regulator
AL038_RS02310	COG2363	Small membrane protein
AL038_RS02315	COG0142	geranyltranstransferase activity
AL038_RS02325	COG0582	viral genome integration into host DNA
AL038_RS02360	COG1598	PFAM Uncharacterised protein family UPF0150
AL038_RS02425	COG1598	PFAM Uncharacterised protein family UPF0150
AL038_RS02465	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
AL038_RS02480	COG0500	methyltransferase
AL038_RS02485	COG2967	ApaG domain
AL038_RS02490	COG2226	methyltransferase
AL038_RS02495	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL038_RS02505	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS02515	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
AL038_RS02525	COG0604	alcohol dehydrogenase
AL038_RS02530	COG3240	lipase activity
AL038_RS02540	COG0784	Response regulator, receiver
AL038_RS02540	COG2205	protein histidine kinase activity
AL038_RS02550	COG2906	2 iron, 2 sulfur cluster binding
AL038_RS02570	COG0071	Belongs to the small heat shock protein (HSP20) family
AL038_RS02580	COG1570	exodeoxyribonuclease VII activity
AL038_RS02585	COG1051	belongs to the nudix hydrolase family
AL038_RS02600	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
AL038_RS02605	COG4942	peptidase
AL038_RS02625	COG0484	heat shock protein binding
AL038_RS02630	COG0402	S-adenosylhomocysteine deaminase activity
AL038_RS02655	COG1551	Could accelerate the degradation of some genes transcripts potentially through selective RNA binding
AL038_RS02660	COG0527	aspartate kinase activity
AL038_RS02665	COG2205	protein histidine kinase activity
AL038_RS02665	COG0784	Response regulator, receiver
AL038_RS02685	COG2030	dehydratase
AL038_RS02690	COG0165	Argininosuccinate lyase
AL038_RS02700	COG0505	Belongs to the CarA family
AL038_RS02705	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
AL038_RS02710	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
AL038_RS02725	COG2941	Oxygenase that introduces the hydroxyl group at carbon five of 2-nonaprenyl-3-methyl-6-methoxy-1,4-benzoquinol resulting in the formation of 2-nonaprenyl-3-methyl-5-hydroxy-6-methoxy-1,4- benzoquinol
AL038_RS02730	COG1586	Catalyzes the decarboxylation of S-adenosylmethionine to S-adenosylmethioninamine (dcAdoMet), the propylamine donor required for the synthesis of the polyamines spermine and spermidine from the diamine putrescine
AL038_RS02735	COG0421	Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy- AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine
AL038_RS02740	COG2373	Large extracellular alpha-helical protein
AL038_RS02745	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
AL038_RS02755	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
AL038_RS02770	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL038_RS02795	COG0815	Transfers the fatty acyl group on membrane lipoproteins
AL038_RS02800	COG0149	triose-phosphate isomerase activity
AL038_RS02805	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL038_RS02810	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
AL038_RS02815	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
AL038_RS02835	COG3597	protein domain associated with
AL038_RS02855	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL038_RS02910	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL038_RS02915	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
AL038_RS02935	COG0069	glutamate synthase activity
AL038_RS02945	COG1330	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit recognizes the wild- type Chi sequence, and when added to isolated RecB increases its ATP-dependent helicase processivity
AL038_RS02960	COG0303	'Molybdopterin
AL038_RS02975	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL038_RS03010	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL038_RS03015	COG0840	transmembrane signaling receptor activity
AL038_RS03035	COG5002	protein histidine kinase activity
AL038_RS03035	COG2198	Histidine kinase
AL038_RS03035	COG0784	Response regulator, receiver
AL038_RS03045	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
AL038_RS03060	COG0584	glycerophosphoryl diester phosphodiesterase
AL038_RS03075	COG0840	transmembrane signaling receptor activity
AL038_RS03080	COG0068	Along with HypE, it catalyzes the synthesis of the CN ligands of the active site iron of NiFe -hydrogenases using carbamoylphosphate as a substrate. It functions as a carbamoyl transferase using carbamoylphosphate as a substrate and transferring the carboxamido moiety in an ATP-dependent reaction to the thiolate of the C-terminal cysteine of HypE yielding a protein-S-carboxamide
AL038_RS03085	COG3954	Phosphoribulokinase
AL038_RS03095	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL038_RS03095	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
AL038_RS03100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
AL038_RS03120	COG0837	glucose binding
AL038_RS03140	COG0792	nuclease activity
AL038_RS03150	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
AL038_RS03155	COG4623	carbon-oxygen lyase activity, acting on polysaccharides
AL038_RS03160	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
AL038_RS03175	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
AL038_RS03180	COG1385	rRNA (uridine-N3-)-methyltransferase activity
AL038_RS03215	COG0741	lytic transglycosylase activity
AL038_RS03225	COG2205	protein histidine kinase activity
AL038_RS03225	COG0784	Response regulator, receiver
AL038_RS03225	COG5002	protein histidine kinase activity
AL038_RS03245	COG2885	chlorophyll binding
AL038_RS03265	COG1166	arginine decarboxylase activity
AL038_RS03290	COG0322	excinuclease ABC activity
AL038_RS03305	COG0508	dehydrogenase complex catalyzes the overall conversion of
AL038_RS03320	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
AL038_RS03330	COG0359	binds to the 23S rRNA
AL038_RS03335	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
AL038_RS03340	COG0360	Binds together with S18 to 16S ribosomal RNA
AL038_RS03345	COG1765	OsmC-like protein
AL038_RS03350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
AL038_RS03355	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL038_RS03365	COG0183	Belongs to the thiolase family
AL038_RS03370	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
AL038_RS03420	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL038_RS03440	COG1858	cytochrome C peroxidase
AL038_RS03475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL038_RS03480	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL038_RS03485	COG4133	protoheme IX ABC transporter activity
AL038_RS03505	COG1129	ABC transporter
AL038_RS03535	COG0321	lipoyl(octanoyl) transferase activity
AL038_RS03540	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
AL038_RS03565	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS03565	COG2205	protein histidine kinase activity
AL038_RS03570	COG0375	protein maturation
AL038_RS03575	COG0298	carbon dioxide binding
AL038_RS03585	COG0493	'glutamate synthase
AL038_RS03590	COG0070	glutamate synthase
AL038_RS03590	COG0067	glutamate synthase
AL038_RS03590	COG0069	glutamate synthase activity
AL038_RS03595	COG2918	glutathione biosynthetic process
AL038_RS03615	COG0735	belongs to the Fur family
AL038_RS03635	COG2914	Belongs to the UPF0125 (RnfH) family
AL038_RS03650	COG4658	electron transport chain
AL038_RS03655	COG4656	Part of a membrane complex involved in electron transport
AL038_RS03660	COG2878	Part of a membrane complex involved in electron transport
AL038_RS03665	COG4657	Part of a membrane complex involved in electron transport
AL038_RS03675	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
AL038_RS03680	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
AL038_RS03685	COG4660	Part of a membrane complex involved in electron transport
AL038_RS03705	COG1597	lipid kinase activity
AL038_RS03720	COG2862	Uncharacterized protein family, UPF0114
AL038_RS03730	COG1459	type II secretion system
AL038_RS03745	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AL038_RS03805	COG1758	RNA polymerase activity
AL038_RS03810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL038_RS03820	COG0006	proline dipeptidase activity
AL038_RS03835	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL038_RS03840	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
AL038_RS03860	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL038_RS03865	COG0418	dihydroorotase activity
AL038_RS03875	COG2203	Gaf domain
AL038_RS03875	COG3706	GGDEF domain
AL038_RS03875	COG4251	negative regulation of phosphorylation
AL038_RS03875	COG5001	Diguanylate cyclase
AL038_RS03885	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL038_RS03890	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL038_RS03900	COG0312	modulator of DNA gyrase
AL038_RS03925	COG1469	GTP cyclohydrolase I activity
AL038_RS03930	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
AL038_RS03955	COG0745	RESPONSE REGULATOR receiver
AL038_RS03960	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL038_RS03960	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
AL038_RS03985	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL038_RS04005	COG0330	HflC and HflK could
AL038_RS04010	COG0037	tRNA processing
AL038_RS04015	COG0560	Phosphoserine phosphatase
AL038_RS04025	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
AL038_RS04030	COG0737	Belongs to the 5'-nucleotidase family
AL038_RS04050	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS04055	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
AL038_RS04065	COG1842	Phage shock protein A
AL038_RS04095	COG1116	anion transmembrane transporter activity
AL038_RS04115	COG0784	Response regulator, receiver
AL038_RS04115	COG2205	protein histidine kinase activity
AL038_RS04115	COG5002	protein histidine kinase activity
AL038_RS04125	COG3155	Displays glyoxalase activity, catalyzing the conversion of glyoxal to glycolate
AL038_RS04135	COG0215	cysteine-tRNA ligase activity
AL038_RS04145	COG0546	phosphoglycolate phosphatase activity
AL038_RS04165	COG0784	Response regulator, receiver
AL038_RS04165	COG5002	protein histidine kinase activity
AL038_RS04165	COG2198	Histidine kinase
AL038_RS04180	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
AL038_RS04200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
AL038_RS04230	COG3218	ABC-type transport auxiliary lipoprotein component
AL038_RS04265	COG3025	triphosphatase activity
AL038_RS04275	COG0583	DNA-binding transcription factor activity
AL038_RS04280	COG2770	Histidine kinase
AL038_RS04280	COG2208	phosphoserine phosphatase activity
AL038_RS04295	COG5002	protein histidine kinase activity
AL038_RS04295	COG2176	DNA-directed DNA polymerase activity
AL038_RS04300	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
AL038_RS04300	COG0662	Cupin 2, conserved barrel domain protein
AL038_RS04305	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
AL038_RS04320	COG3001	Fructosamine kinase
AL038_RS04330	COG0784	Response regulator, receiver
AL038_RS04330	COG2205	protein histidine kinase activity
AL038_RS04340	COG2197	response regulator
AL038_RS04370	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
AL038_RS04380	COG3755	Protein conserved in bacteria
AL038_RS04385	COG0860	N-Acetylmuramoyl-L-alanine amidase
AL038_RS04440	COG0312	modulator of DNA gyrase
AL038_RS04445	COG4797	methyltransferase
AL038_RS04445	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
AL038_RS04465	COG1194	a g-specific adenine glycosylase
AL038_RS04470	COG2924	Could be a mediator in iron transactions between iron acquisition and iron-requiring processes, such as synthesis and or repair of Fe-S clusters in biosynthetic enzymes
AL038_RS04485	COG0357	Ribosomal RNA small subunit methyltransferase G
AL038_RS04490	COG2921	Belongs to the UPF0250 family
AL038_RS04495	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
AL038_RS04505	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
AL038_RS04510	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
AL038_RS04515	COG2205	protein histidine kinase activity
AL038_RS04515	COG3437	response regulator, receiver
AL038_RS04515	COG4999	Histidine kinase
AL038_RS04515	COG3850	Histidine kinase
AL038_RS04520	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL038_RS04530	COG1738	Involved in the import of queuosine (Q) precursors, required for Q precursor salvage
AL038_RS04535	COG3320	Male sterility
AL038_RS04535	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL038_RS04550	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL038_RS04555	COG3604	Transcriptional regulator
AL038_RS04560	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL038_RS04565	COG0730	response to heat
AL038_RS04575	COG3267	Type II secretory pathway component ExeA
AL038_RS04575	COG3409	Peptidoglycan-binding domain 1 protein
AL038_RS04600	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL038_RS04605	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
AL038_RS04605	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
AL038_RS04635	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL038_RS04640	COG2205	protein histidine kinase activity
AL038_RS04640	COG2202	Pas domain
AL038_RS04655	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL038_RS04670	COG2914	Belongs to the UPF0125 (RnfH) family
AL038_RS04690	COG0386	Belongs to the glutathione peroxidase family
AL038_RS04695	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
AL038_RS04705	COG5265	(ABC) transporter
AL038_RS04720	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL038_RS04765	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
AL038_RS04785	COG1773	rubredoxin
AL038_RS04790	COG2208	phosphoserine phosphatase activity
AL038_RS04790	COG2770	Histidine kinase
AL038_RS04800	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
AL038_RS04805	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
AL038_RS04810	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL038_RS04815	COG0217	transcriptional regulatory protein
AL038_RS04820	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
AL038_RS04835	COG1215	transferase activity, transferring glycosyl groups
AL038_RS04845	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL038_RS04845	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
AL038_RS04850	COG0285	dihydrofolate synthase activity
AL038_RS04855	COG0148	phosphopyruvate hydratase activity
AL038_RS04860	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL038_RS04865	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
AL038_RS04875	COG1587	Uroporphyrinogen-III synthase
AL038_RS04885	COG1017	nitric oxide dioxygenase activity
AL038_RS04885	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL038_RS04895	COG0442	prolyl-tRNA aminoacylation
AL038_RS04910	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
AL038_RS04920	COG0745	RESPONSE REGULATOR receiver
AL038_RS04925	COG0643	Histidine kinase
AL038_RS04925	COG2198	Histidine kinase
AL038_RS04930	COG0835	chemotaxis
AL038_RS04975	COG2132	Multicopper oxidase
AL038_RS04985	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
AL038_RS04990	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
AL038_RS04995	COG4181	ATPase activity
AL038_RS05015	COG0753	catalase activity
AL038_RS05020	COG4174	ABC transporter (Permease)
AL038_RS05030	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
AL038_RS05035	COG2205	protein histidine kinase activity
AL038_RS05035	COG0784	Response regulator, receiver
AL038_RS05035	COG2198	Histidine kinase
AL038_RS05040	COG1139	Iron-sulfur cluster binding protein
AL038_RS05045	COG1556	Lactate utilization protein
AL038_RS05050	COG0745	RESPONSE REGULATOR receiver
AL038_RS05055	COG2176	DNA-directed DNA polymerase activity
AL038_RS05055	COG5002	protein histidine kinase activity
AL038_RS05065	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
AL038_RS05085	COG0714	Associated with various cellular activities
AL038_RS05100	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
AL038_RS05105	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
AL038_RS05130	COG5002	protein histidine kinase activity
AL038_RS05130	COG5001	Diguanylate cyclase
AL038_RS05160	COG3437	response regulator, receiver
AL038_RS05160	COG2205	protein histidine kinase activity
AL038_RS05160	COG4999	Histidine kinase
AL038_RS05160	COG3850	Histidine kinase
AL038_RS05165	COG4999	Histidine kinase
AL038_RS05165	COG3850	Histidine kinase
AL038_RS05165	COG3437	response regulator, receiver
AL038_RS05165	COG2205	protein histidine kinase activity
AL038_RS05185	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL038_RS05200	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
AL038_RS05205	COG2050	protein possibly involved in aromatic compounds catabolism
AL038_RS05210	COG4999	Histidine kinase
AL038_RS05210	COG3850	Histidine kinase
AL038_RS05210	COG3437	response regulator, receiver
AL038_RS05210	COG2205	protein histidine kinase activity
AL038_RS05215	COG3706	GGDEF domain
AL038_RS05225	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
AL038_RS05285	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
AL038_RS05290	COG0277	FAD linked oxidase domain protein
AL038_RS05295	COG0247	lactate metabolic process
AL038_RS05320	COG3008	intermembrane lipid transfer
AL038_RS05325	COG2995	paraquat-inducible protein a
AL038_RS05355	COG0420	3'-5' exonuclease activity
AL038_RS05360	COG0784	Response regulator, receiver
AL038_RS05360	COG2205	protein histidine kinase activity
AL038_RS05360	COG2198	Histidine kinase
AL038_RS05375	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
AL038_RS05430	COG2205	protein histidine kinase activity
AL038_RS05430	COG0784	Response regulator, receiver
AL038_RS05435	COG1942	4-Oxalocrotonate Tautomerase
AL038_RS05440	COG0464	growth
AL038_RS05455	COG0697	spore germination
AL038_RS05460	COG0463	Glycosyl transferase, family 2
AL038_RS05465	COG0339	signal peptide processing
AL038_RS05475	COG1131	(ABC) transporter
AL038_RS05495	COG0187	DNA topoisomerase II activity
AL038_RS05525	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
AL038_RS05530	COG1053	succinate dehydrogenase
AL038_RS05535	COG2142	Succinate dehydrogenase hydrophobic membrane anchor
AL038_RS05540	COG2009	succinate dehydrogenase
AL038_RS05555	COG2176	DNA-directed DNA polymerase activity
AL038_RS05560	COG2943	transferase activity, transferring hexosyl groups
AL038_RS05570	COG0494	nUDIX hydrolase
AL038_RS05575	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL038_RS05580	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
AL038_RS05585	COG0519	Catalyzes the synthesis of GMP from XMP
AL038_RS05595	COG3116	cell division
AL038_RS05605	COG1643	Atp-dependent helicase
AL038_RS05615	COG0864	Transcriptional regulator
AL038_RS05620	COG0641	radical SAM
AL038_RS05625	COG0784	Response regulator, receiver
AL038_RS05625	COG5002	protein histidine kinase activity
AL038_RS05630	COG0252	asparaginase activity
AL038_RS05635	COG2217	Heavy metal translocating P-type atpase
AL038_RS05665	COG1918	ferrous iron import across plasma membrane
AL038_RS05685	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
AL038_RS05705	COG1472	Belongs to the glycosyl hydrolase 3 family
AL038_RS05735	COG2192	nodulation
AL038_RS05745	COG2192	nodulation
AL038_RS05820	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
AL038_RS05835	COG0793	Belongs to the peptidase S41A family
AL038_RS05840	COG4942	peptidase
AL038_RS05895	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
AL038_RS05895	COG0546	phosphoglycolate phosphatase activity
AL038_RS05900	COG0277	FAD linked oxidase domain protein
AL038_RS05915	COG0151	Belongs to the GarS family
AL038_RS05920	COG0138	bifunctional purine biosynthesis protein purh
AL038_RS05975	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL038_RS06000	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
AL038_RS06015	COG2206	PFAM metal-dependent phosphohydrolase, HD sub domain
AL038_RS06030	COG2010	Cytochrome c
AL038_RS06045	COG3278	Belongs to the heme-copper respiratory oxidase family
AL038_RS06055	COG2217	Heavy metal translocating P-type atpase
AL038_RS06060	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL038_RS06070	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
AL038_RS06105	COG0523	cobalamin synthesis protein
AL038_RS06145	COG2890	protein-(glutamine-N5) methyltransferase activity
AL038_RS06155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL038_RS06160	COG0582	viral genome integration into host DNA
AL038_RS06165	COG0101	tRNA pseudouridine synthase activity
AL038_RS06175	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
AL038_RS06180	COG0473	3-isopropylmalate dehydrogenase activity
AL038_RS06190	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
AL038_RS06205	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
AL038_RS06215	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL038_RS06220	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
AL038_RS06230	COG5002	protein histidine kinase activity
AL038_RS06230	COG2198	Histidine kinase
AL038_RS06230	COG0784	Response regulator, receiver
AL038_RS06240	COG0641	radical SAM
AL038_RS06250	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
AL038_RS06255	COG1132	(ABC) transporter
AL038_RS06260	COG1704	LemA family
AL038_RS06265	COG0084	hydrolase, TatD family'
AL038_RS06270	COG1179	involved in molybdopterin and THIamine biosynthesis family 1
AL038_RS06275	COG0784	Response regulator, receiver
AL038_RS06275	COG2205	protein histidine kinase activity
AL038_RS06280	COG5002	protein histidine kinase activity
AL038_RS06280	COG0784	Response regulator, receiver
AL038_RS06290	COG0270	DNA (cytosine-5-)-methyltransferase activity
AL038_RS06300	COG0156	8-amino-7-oxononanoate synthase activity
AL038_RS06305	COG2957	Belongs to the agmatine deiminase family
AL038_RS06320	COG0277	FAD linked oxidase domain protein
AL038_RS06330	COG0586	Pfam SNARE associated Golgi protein
AL038_RS06345	COG0488	(ABC) transporter
AL038_RS06355	COG3030	protein affecting phage T7 exclusion by the F plasmid
AL038_RS06365	COG1012	belongs to the aldehyde dehydrogenase family
AL038_RS06375	COG2205	protein histidine kinase activity
AL038_RS06375	COG2202	Pas domain
AL038_RS06380	COG0563	adenylate kinase activity
AL038_RS06405	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
AL038_RS06410	COG2255	four-way junction helicase activity
AL038_RS06415	COG0824	Thioesterase
AL038_RS06420	COG0811	peptide transport
AL038_RS06435	COG0823	Involved in the tonB-independent uptake of proteins
AL038_RS06440	COG2885	chlorophyll binding
AL038_RS06450	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
AL038_RS06460	COG3577	Aspartyl protease
AL038_RS06470	COG0741	lytic transglycosylase activity
AL038_RS06485	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL038_RS06545	COG0805	protein transport
AL038_RS06550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL038_RS06555	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
AL038_RS06565	COG0140	phosphoribosyl-ATP diphosphatase activity
AL038_RS06575	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
AL038_RS06585	COG0107	imidazoleglycerol-phosphate synthase activity
AL038_RS06590	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
AL038_RS06595	COG0840	transmembrane signaling receptor activity
AL038_RS06615	COG2833	Protein of unknown function (DUF455)
AL038_RS06640	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
AL038_RS06645	COG3047	cAMP biosynthetic process
AL038_RS06650	COG2202	Pas domain
AL038_RS06650	COG2205	protein histidine kinase activity
AL038_RS06670	COG0667	Aldo Keto reductase
AL038_RS06690	COG0680	Initiates the rapid degradation of small, acid-soluble proteins during spore germination
AL038_RS06695	COG2204	response regulator
AL038_RS06705	COG0668	transmembrane transport
AL038_RS06710	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL038_RS06715	COG0697	spore germination
AL038_RS06730	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL038_RS06730	COG0574	Belongs to the PEP-utilizing enzyme family
AL038_RS06760	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
AL038_RS06765	COG0009	L-threonylcarbamoyladenylate synthase
AL038_RS06770	COG0408	coproporphyrinogen oxidase activity
AL038_RS06775	COG4656	Part of a membrane complex involved in electron transport
AL038_RS06795	COG3317	Gram-negative-bacterium-type cell outer membrane assembly
AL038_RS06805	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
AL038_RS06810	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
AL038_RS06825	COG1192	Involved in chromosome partitioning
AL038_RS06830	COG2204	response regulator
AL038_RS06835	COG2199	diguanylate cyclase activity
AL038_RS06835	COG2203	Gaf domain
AL038_RS06855	COG4717	serine-type aminopeptidase activity
AL038_RS06860	COG0288	reversible hydration of carbon dioxide
AL038_RS06905	COG1752	Esterase of the alpha-beta hydrolase superfamily
AL038_RS06910	COG1160	GTP binding
AL038_RS06930	COG1960	acyl-CoA dehydrogenase activity
AL038_RS06940	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
AL038_RS06945	COG0732	type I restriction modification DNA specificity domain
AL038_RS06950	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL038_RS06965	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS06980	COG0697	spore germination
AL038_RS06990	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS07005	COG4191	Histidine kinase
AL038_RS07015	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL038_RS07045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL038_RS07050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
AL038_RS07055	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL038_RS07065	COG5000	phosphorelay sensor kinase activity
AL038_RS07070	COG2204	response regulator
AL038_RS07075	COG0569	domain protein
AL038_RS07090	COG0840	transmembrane signaling receptor activity
AL038_RS07120	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL038_RS07125	COG0247	lactate metabolic process
AL038_RS07135	COG1640	4-alpha-glucanotransferase
AL038_RS07145	COG2919	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic
AL038_RS07150	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
AL038_RS07155	COG1409	Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes
AL038_RS07160	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
AL038_RS07160	COG0644	oxidoreductase
AL038_RS07175	COG0745	RESPONSE REGULATOR receiver
AL038_RS07180	COG2205	protein histidine kinase activity
AL038_RS07185	COG0352	thiamine-phosphate diphosphorylase activity
AL038_RS07195	COG2022	thiamine diphosphate biosynthetic process
AL038_RS07210	COG0438	transferase activity, transferring glycosyl groups
AL038_RS07235	COG3206	protein involved in exopolysaccharide biosynthesis
AL038_RS07235	COG0489	protein tyrosine kinase activity
AL038_RS07245	COG2358	TRAP transporter, solute receptor (TAXI family
AL038_RS07260	COG2205	protein histidine kinase activity
AL038_RS07260	COG0784	Response regulator, receiver
AL038_RS07275	COG2208	phosphoserine phosphatase activity
AL038_RS07285	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS07310	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
AL038_RS07320	COG2226	methyltransferase
AL038_RS07330	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
AL038_RS07340	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
AL038_RS07350	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
AL038_RS07360	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
AL038_RS07365	COG0535	radical SAM domain protein
AL038_RS07375	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
AL038_RS07400	COG1131	(ABC) transporter
AL038_RS07405	COG0616	signal peptide processing
AL038_RS07415	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
AL038_RS07425	COG2264	protein methyltransferase activity
AL038_RS07430	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
AL038_RS07445	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
AL038_RS07465	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL038_RS07470	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL038_RS07475	COG1611	Belongs to the LOG family
AL038_RS07500	COG2920	part of a sulfur-relay system
AL038_RS07505	COG2168	tRNA wobble position uridine thiolation
AL038_RS07510	COG2923	Belongs to the DsrF TusC family
AL038_RS07515	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
AL038_RS07520	COG0484	heat shock protein binding
AL038_RS07525	COG1215	transferase activity, transferring glycosyl groups
AL038_RS07535	COG0756	dUTP diphosphatase activity
AL038_RS07565	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
AL038_RS07580	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
AL038_RS07600	COG1959	2 iron, 2 sulfur cluster binding
AL038_RS07605	COG1104	cysteine desulfurase activity
AL038_RS07610	COG1104	cysteine desulfurase activity
AL038_RS07625	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
AL038_RS07630	COG2877	3-deoxy-8-phosphooctulonate synthase activity
AL038_RS07640	COG0497	DNA recombination
AL038_RS07645	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL038_RS07650	COG0617	tRNA 3'-terminal CCA addition
AL038_RS07690	COG0542	response to heat
AL038_RS07695	COG1968	undecaprenyl-diphosphatase activity
AL038_RS07705	COG3852	Histidine kinase
AL038_RS07710	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL038_RS07715	COG2911	Protein conserved in bacteria
AL038_RS07730	COG4260	virion core protein, lumpy skin disease virus
AL038_RS07740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
AL038_RS07745	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
AL038_RS07750	COG0686	Belongs to the AlaDH PNT family
AL038_RS07765	COG1610	YqeY-like protein
AL038_RS07770	COG0358	DNA primase activity
AL038_RS07785	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
AL038_RS07790	COG1137	ATPase activity
AL038_RS07795	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
AL038_RS07810	COG1493	Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion
AL038_RS07820	COG2304	oxidoreductase activity
AL038_RS07825	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
AL038_RS07830	COG5002	protein histidine kinase activity
AL038_RS07830	COG0784	Response regulator, receiver
AL038_RS07830	COG2198	Histidine kinase
AL038_RS07855	COG2198	Histidine kinase
AL038_RS07855	COG0784	Response regulator, receiver
AL038_RS07855	COG2205	protein histidine kinase activity
AL038_RS07860	COG0012	GTP binding
AL038_RS07865	COG1083	cytidylyl-transferase
AL038_RS07875	COG2089	acid synthase
AL038_RS07885	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
AL038_RS07890	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
AL038_RS07895	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
AL038_RS07905	COG0297	glycogen (starch) synthase activity
AL038_RS07910	COG0343	queuine tRNA-ribosyltransferase activity
AL038_RS07915	COG2202	Pas domain
AL038_RS07915	COG2205	protein histidine kinase activity
AL038_RS07945	COG3038	cytochrome b561
AL038_RS07965	COG2885	chlorophyll binding
AL038_RS07970	COG0829	nickel cation binding
AL038_RS07990	COG1660	Displays ATPase and GTPase activities
AL038_RS07995	COG0126	phosphoglycerate kinase activity
AL038_RS08000	COG2171	N-acyltransferase activity
AL038_RS08005	COG0436	Aminotransferase
AL038_RS08010	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
AL038_RS08020	COG0745	RESPONSE REGULATOR receiver
AL038_RS08025	COG2205	protein histidine kinase activity
AL038_RS08030	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
AL038_RS08035	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
AL038_RS08040	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
AL038_RS08050	COG0180	Tryptophanyl-tRNA synthetase
AL038_RS08085	COG1199	ATP-dependent helicase activity
AL038_RS08085	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL038_RS08090	COG0347	Belongs to the P(II) protein family
AL038_RS08095	COG0004	ammonium transporteR
AL038_RS08100	COG0004	ammonium transporteR
AL038_RS08115	COG0837	glucose binding
AL038_RS08135	COG0105	UTP biosynthetic process
AL038_RS08140	COG0820	rRNA (adenine-C2-)-methyltransferase activity
AL038_RS08150	COG1426	Protein conserved in bacteria
AL038_RS08155	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
AL038_RS08160	COG0124	histidyl-tRNA synthetase
AL038_RS08165	COG2976	Protein conserved in bacteria
AL038_RS08175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS08175	COG2205	protein histidine kinase activity
AL038_RS08195	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
AL038_RS08210	COG0430	RNA-3'-phosphate cyclase activity
AL038_RS08225	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
AL038_RS08230	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
AL038_RS08240	COG0330	HflC and HflK could
AL038_RS08245	COG0330	HflC and HflK could
AL038_RS08265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
AL038_RS08270	COG1923	regulation of RNA biosynthetic process
AL038_RS08275	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
AL038_RS08280	COG1459	type II secretion system
AL038_RS08295	COG0494	nUDIX hydrolase
AL038_RS08305	COG0588	phosphoglycerate mutase activity
AL038_RS08315	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL038_RS08320	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
AL038_RS08325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
AL038_RS08335	COG0825	malonyl-CoA metabolic process
AL038_RS08350	COG0557	exoribonuclease II activity
AL038_RS08380	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
AL038_RS08395	COG2165	general secretion pathway protein
AL038_RS08400	COG0484	heat shock protein binding
AL038_RS08425	COG0504	CTP synthase activity
AL038_RS08430	COG2084	Dehydrogenase
AL038_RS08440	COG1346	cytolysis
AL038_RS08455	COG2202	Pas domain
AL038_RS08455	COG2205	protein histidine kinase activity
AL038_RS08480	COG0752	glycyl-tRNA synthetase alpha subunit
AL038_RS08485	COG0751	glycine-tRNA ligase activity
AL038_RS08490	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
AL038_RS08500	COG1705	Flagellar rod assembly protein muramidase FlgJ
AL038_RS08500	COG1388	LysM domain
AL038_RS08505	COG4942	peptidase
AL038_RS08520	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
AL038_RS08545	COG3114	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
AL038_RS08555	COG1138	Cytochrome C-type biogenesis protein
AL038_RS08565	COG2217	Heavy metal translocating P-type atpase
AL038_RS08575	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
AL038_RS08575	COG1648	precorrin-2 dehydrogenase activity
AL038_RS08580	COG0425	Belongs to the sulfur carrier protein TusA family
AL038_RS08585	COG2210	Belongs to the sulfur carrier protein TusA family
AL038_RS08590	COG0328	RNA-DNA hybrid ribonuclease activity
AL038_RS08600	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
AL038_RS08620	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
AL038_RS08625	COG0589	response to stress
AL038_RS08640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL038_RS08640	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL038_RS08645	COG0179	Fumarylacetoacetate (FAA) hydrolase
AL038_RS08650	COG3932	Exopolysaccharide synthesis, ExoD
AL038_RS08660	COG0739	heme binding
AL038_RS08660	COG0741	lytic transglycosylase activity
AL038_RS08660	COG1196	nuclear chromosome segregation
AL038_RS08665	COG0604	alcohol dehydrogenase
AL038_RS08680	COG3243	poly(R)-hydroxyalkanoic acid synthase
AL038_RS08685	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL038_RS08685	COG0515	serine threonine protein kinase
AL038_RS08695	COG2902	Dehydrogenase
AL038_RS08705	COG0573	inorganic phosphate transmembrane transporter activity
AL038_RS08710	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
AL038_RS08715	COG0704	Plays a role in the regulation of phosphate uptake
AL038_RS08735	COG1960	acyl-CoA dehydrogenase activity
AL038_RS08745	COG3707	response regulator
AL038_RS08750	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
AL038_RS08750	COG1116	anion transmembrane transporter activity
AL038_RS08755	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
AL038_RS08760	COG1116	anion transmembrane transporter activity
AL038_RS08765	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
AL038_RS08770	COG2146	nitrite reductase [NAD(P)H] activity
AL038_RS08775	COG0243	molybdopterin cofactor binding
AL038_RS08785	COG1495	Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein
AL038_RS08795	COG1562	ergosterol biosynthetic process
AL038_RS08800	COG0330	HflC and HflK could
AL038_RS08805	COG0390	transport system, permease component
AL038_RS08815	COG1795	PFAM Formaldehyde-activating enzyme (Fae)
AL038_RS08830	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
AL038_RS08835	COG0693	protein deglycase activity
AL038_RS08845	COG1216	Glycosyl transferase, family 2
AL038_RS08845	COG0438	transferase activity, transferring glycosyl groups
AL038_RS08855	COG0791	NLP P60 protein
AL038_RS08860	COG0450	alkyl hydroperoxide reductase
AL038_RS08885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
AL038_RS08890	COG1832	CoA-binding protein
AL038_RS08920	COG0166	Belongs to the GPI family
AL038_RS08945	COG4232	protein-disulfide reductase activity
AL038_RS08950	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL038_RS08970	COG4191	Histidine kinase
AL038_RS09010	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL038_RS09015	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL038_RS09030	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
AL038_RS09050	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
AL038_RS09055	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
AL038_RS09075	COG0438	transferase activity, transferring glycosyl groups
AL038_RS09080	COG0367	asparagine synthase
AL038_RS09085	COG0463	Glycosyl transferase, family 2
AL038_RS09095	COG4106	trans-aconitate 2-methyltransferase activity
AL038_RS09105	COG3300	MHYT domain
AL038_RS09105	COG5001	Diguanylate cyclase
AL038_RS09110	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
AL038_RS09115	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL038_RS09120	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL038_RS09125	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL038_RS09130	COG0649	NAD binding
AL038_RS09135	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL038_RS09145	COG1034	ATP synthesis coupled electron transport
AL038_RS09150	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
AL038_RS09155	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
AL038_RS09170	COG0713	ATP synthesis coupled electron transport
AL038_RS09185	COG1007	ATP synthesis coupled electron transport
AL038_RS09190	COG1555	photosystem II stabilization
AL038_RS09195	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
AL038_RS09200	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
AL038_RS09220	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
AL038_RS09230	COG0356	it plays a direct role in the translocation of protons across the membrane
AL038_RS09235	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL038_RS09240	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
AL038_RS09245	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
AL038_RS09250	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
AL038_RS09255	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
AL038_RS09260	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
AL038_RS09265	COG0355	proton-transporting ATP synthase activity, rotational mechanism
AL038_RS09270	COG3284	Transcriptional regulator
AL038_RS09285	COG3012	SEC-C Motif Domain Protein
AL038_RS09290	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL038_RS09295	COG1127	ABC transporter
AL038_RS09305	COG2205	protein histidine kinase activity
AL038_RS09305	COG2198	Histidine kinase
AL038_RS09305	COG0784	Response regulator, receiver
AL038_RS09315	COG0501	Belongs to the peptidase M48B family
AL038_RS09325	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL038_RS09325	COG0515	serine threonine protein kinase
AL038_RS09555	COG2842	Transposition protein
AL038_RS09560	COG2801	Transposase and inactivated derivatives
AL038_RS09625	COG3275	phosphorelay sensor kinase activity
AL038_RS09650	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
AL038_RS09655	COG0085	RNA polymerase activity
AL038_RS09660	COG0222	ribosome binding
AL038_RS09665	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
AL038_RS09670	COG0081	regulation of translation
AL038_RS09675	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
AL038_RS09685	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
AL038_RS09695	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL038_RS09725	COG1218	3'(2'),5'-bisphosphate nucleotidase
AL038_RS09745	COG1573	uracil-dna glycosylase
AL038_RS09775	COG0784	Response regulator, receiver
AL038_RS09775	COG2205	protein histidine kinase activity
AL038_RS09780	COG5001	Diguanylate cyclase
AL038_RS09780	COG2203	Gaf domain
AL038_RS09780	COG4251	negative regulation of phosphorylation
AL038_RS09780	COG3706	GGDEF domain
AL038_RS09795	COG3302	dmso reductase anchor subunit
AL038_RS09800	COG0437	4 iron, 4 sulfur cluster binding
AL038_RS09805	COG0243	molybdopterin cofactor binding
AL038_RS09810	COG0552	protein localization to endoplasmic reticulum
AL038_RS09820	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL038_RS09820	COG0515	serine threonine protein kinase
AL038_RS09855	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
AL038_RS09870	COG0019	diaminopimelate decarboxylase activity
AL038_RS09895	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
AL038_RS09935	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
AL038_RS09960	COG0523	cobalamin synthesis protein
AL038_RS09970	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
AL038_RS09980	COG0033	Phosphoglucomutase
AL038_RS09990	COG0723	plastoquinol--plastocyanin reductase activity
AL038_RS09995	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
AL038_RS10000	COG2857	Cytochrome c1
AL038_RS10005	COG2969	positive regulation of protein catabolic process
AL038_RS10020	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
AL038_RS10025	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL038_RS10030	COG2226	methyltransferase
AL038_RS10040	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
AL038_RS10045	COG4137	Cytochrome C assembly protein
AL038_RS10060	COG0768	penicillin binding
AL038_RS10065	COG0784	Response regulator, receiver
AL038_RS10065	COG3437	response regulator, receiver
AL038_RS10070	COG1519	Transferase
AL038_RS10075	COG0183	Belongs to the thiolase family
AL038_RS10085	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS10140	COG0237	dephospho-CoA kinase activity
AL038_RS10145	COG4582	Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity
AL038_RS10170	COG0840	transmembrane signaling receptor activity
AL038_RS10175	COG0784	Response regulator, receiver
AL038_RS10175	COG0643	Histidine kinase
AL038_RS10175	COG2198	Histidine kinase
AL038_RS10205	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
AL038_RS10215	COG0443	Heat shock 70 kDa protein
AL038_RS10225	COG0791	NLP P60 protein
AL038_RS10235	COG1846	Transcriptional regulator
AL038_RS10240	COG2703	oxygen carrier activity
AL038_RS10250	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
AL038_RS10255	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
AL038_RS10260	COG1538	Outer membrane efflux protein
AL038_RS10265	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
AL038_RS10285	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL038_RS10290	COG2813	Specifically methylates the guanine in position
AL038_RS10290	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
AL038_RS10300	COG0220	tRNA (guanine-N7-)-methyltransferase activity
AL038_RS10305	COG0254	rRNA binding
AL038_RS10320	COG1131	(ABC) transporter
AL038_RS10330	COG0602	queuosine metabolic process
AL038_RS10335	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
AL038_RS10340	COG0484	heat shock protein binding
AL038_RS10345	COG0443	Heat shock 70 kDa protein
AL038_RS10350	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
AL038_RS10355	COG1420	regulation of RNA biosynthetic process
AL038_RS10370	COG0708	Exodeoxyribonuclease III
AL038_RS10380	COG0753	catalase activity
AL038_RS10385	COG2010	Cytochrome c
AL038_RS10390	COG4999	Histidine kinase
AL038_RS10390	COG2205	protein histidine kinase activity
AL038_RS10390	COG3437	response regulator, receiver
AL038_RS10390	COG3850	Histidine kinase
AL038_RS10425	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
AL038_RS10480	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
AL038_RS10485	COG2814	Major facilitator Superfamily
AL038_RS10500	COG0463	Glycosyl transferase, family 2
AL038_RS10505	COG1965	Belongs to the frataxin family
AL038_RS10520	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS10550	COG4783	chaperone-mediated protein folding
AL038_RS10560	COG1131	(ABC) transporter
AL038_RS10575	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
AL038_RS10590	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
AL038_RS10605	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
AL038_RS10635	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
AL038_RS10650	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
AL038_RS10655	COG3383	formate dehydrogenase (NAD+) activity
AL038_RS10665	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
AL038_RS10680	COG3158	transport of potassium into the cell
AL038_RS10695	COG0084	hydrolase, TatD family'
AL038_RS10700	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
AL038_RS10710	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
AL038_RS10715	COG0464	growth
AL038_RS10735	COG3411	Ferredoxin
AL038_RS10750	COG2037	Catalyzes the transfer of a formyl group from 5-formyl tetrahydromethanopterin (5-formyl-H(4)MPT) to methanofuran (MFR) so as to produce formylmethanofuran (formyl-MFR) and tetrahydromethanopterin (H(4)MPT)
AL038_RS10765	COG2304	oxidoreductase activity
AL038_RS10810	COG0513	Belongs to the DEAD box helicase family
AL038_RS10820	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL038_RS10835	COG1136	(ABC) transporter
AL038_RS10840	COG4591	ABC-type transport system involved in lipoprotein release permease component
AL038_RS10845	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
AL038_RS10860	COG1131	(ABC) transporter
AL038_RS10865	COG0842	Transport permease protein
AL038_RS10870	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL038_RS10875	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
AL038_RS10880	COG1862	Preprotein translocase
AL038_RS10900	COG1024	Enoyl-CoA hydratase
AL038_RS10935	COG2177	Part of the ABC transporter FtsEX involved in
AL038_RS10945	COG2003	Belongs to the UPF0758 family
AL038_RS10970	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
AL038_RS10975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
AL038_RS10980	COG0291	Belongs to the bacterial ribosomal protein bL35 family
AL038_RS10985	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
AL038_RS10995	COG2201	protein-glutamate methylesterase activity
AL038_RS11010	COG0616	signal peptide processing
AL038_RS11010	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
AL038_RS11100	COG0167	dihydroorotate dehydrogenase activity
AL038_RS11110	COG1643	Atp-dependent helicase
AL038_RS11120	COG1858	cytochrome C peroxidase
AL038_RS11140	COG0583	DNA-binding transcription factor activity
AL038_RS11145	COG2205	protein histidine kinase activity
AL038_RS11145	COG0784	Response regulator, receiver
AL038_RS11150	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
AL038_RS11175	COG3258	Cytochrome c
AL038_RS11180	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL038_RS11185	COG0714	Associated with various cellular activities
AL038_RS11195	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
AL038_RS11215	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
AL038_RS11220	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
AL038_RS11230	COG3245	cytochrome
AL038_RS11255	COG0784	Response regulator, receiver
AL038_RS11255	COG2205	protein histidine kinase activity
AL038_RS11275	COG5464	transposase or invertase
AL038_RS11295	COG0635	Involved in the biosynthesis of porphyrin-containing compound
AL038_RS11310	COG0795	lipopolysaccharide-transporting ATPase activity
AL038_RS11325	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
AL038_RS11355	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL038_RS11370	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
AL038_RS11375	COG2894	cell division
AL038_RS11380	COG0850	regulation of cytokinetic process
AL038_RS11440	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
AL038_RS11445	COG3384	dioxygenase
AL038_RS11450	COG1741	Belongs to the pirin family
AL038_RS11460	COG0267	Belongs to the bacterial ribosomal protein bL33 family
AL038_RS11465	COG0227	Belongs to the bacterial ribosomal protein bL28 family
AL038_RS11515	COG4249	Peptidase C14 caspase catalytic subunit p20
AL038_RS11515	COG2319	Wd-40 repeat
AL038_RS11530	COG1012	belongs to the aldehyde dehydrogenase family
AL038_RS11560	COG1210	Utp--glucose-1-phosphate uridylyltransferase
AL038_RS11575	COG1605	Chorismate mutase
AL038_RS11575	COG0077	Prephenate dehydratase
AL038_RS11580	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL038_RS11600	COG0582	viral genome integration into host DNA
AL038_RS11670	COG0640	Transcriptional regulator
AL038_RS11680	COG2890	protein-(glutamine-N5) methyltransferase activity
AL038_RS11730	COG2198	Histidine kinase
AL038_RS11730	COG0643	Histidine kinase
AL038_RS11730	COG0784	Response regulator, receiver
AL038_RS11775	COG5002	protein histidine kinase activity
AL038_RS11775	COG2205	protein histidine kinase activity
AL038_RS11775	COG0784	Response regulator, receiver
AL038_RS11795	COG0047	phosphoribosylformylglycinamidine synthase activity
AL038_RS11795	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
AL038_RS11800	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
AL038_RS11810	COG1488	Catalyzes the synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP
AL038_RS11815	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
AL038_RS11830	COG2319	Wd-40 repeat
AL038_RS11830	COG4249	Peptidase C14 caspase catalytic subunit p20
AL038_RS11845	COG2308	Evidence 4 Homologs of previously reported genes of
AL038_RS11895	COG0650	Formate hydrogenlyase subunit 4
AL038_RS11940	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
AL038_RS11945	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL038_RS11950	COG4172	Belongs to the ABC transporter superfamily
AL038_RS11960	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
AL038_RS11970	COG1280	lysine exporter protein (LysE YggA)
AL038_RS11995	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
AL038_RS12005	COG3180	Ammonia monooxygenase
AL038_RS12010	COG1234	tRNA 3'-trailer cleavage
AL038_RS12015	COG0745	RESPONSE REGULATOR receiver
AL038_RS12025	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
AL038_RS12040	COG2183	response to ionizing radiation
AL038_RS12045	COG3300	MHYT domain
AL038_RS12045	COG5001	Diguanylate cyclase
AL038_RS12055	COG0720	synthase
AL038_RS12070	COG1360	Flagellar Motor Protein
AL038_RS12095	COG4555	ABC transporter
AL038_RS12135	COG1064	alcohol dehydrogenase
AL038_RS12185	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
AL038_RS12215	COG1733	regulation of RNA biosynthetic process
AL038_RS12220	COG0702	epimerase
AL038_RS12255	COG0279	D-glycero-D-manno-heptose 7-phosphate biosynthetic process
AL038_RS12260	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
AL038_RS12270	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
AL038_RS12275	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
AL038_RS12315	COG0582	viral genome integration into host DNA
AL038_RS12325	COG2337	Toxic component of a toxin-antitoxin (TA) module
AL038_RS12345	COG2208	phosphoserine phosphatase activity
AL038_RS12360	COG1993	acr, cog1993
AL038_RS12365	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
AL038_RS12375	COG0601	transmembrane transport
AL038_RS12390	COG3909	cytochrome
AL038_RS12435	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL038_RS12440	COG1309	transcriptional regulator
AL038_RS12475	COG1842	Phage shock protein A
AL038_RS12490	COG0606	chelatase, subunit chli
AL038_RS12505	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS12515	COG0863	Belongs to the N(4) N(6)-methyltransferase family
AL038_RS12535	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS12540	COG5635	Nacht domain
AL038_RS12540	COG2319	Wd-40 repeat
AL038_RS12565	COG0410	ABC transporter
AL038_RS12590	COG1022	Amp-dependent synthetase and ligase
AL038_RS12600	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
AL038_RS12610	COG3552	Protein containing von Willebrand factor type A (VWA) domain
AL038_RS12615	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
AL038_RS12665	COG3850	Histidine kinase
AL038_RS12665	COG2205	protein histidine kinase activity
AL038_RS12665	COG4999	Histidine kinase
AL038_RS12665	COG3437	response regulator, receiver
AL038_RS12670	COG2205	protein histidine kinase activity
AL038_RS12680	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
AL038_RS12695	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
AL038_RS12700	COG4208	sulfate ABC transporter
AL038_RS12705	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
AL038_RS12735	COG2354	Protein conserved in bacteria
AL038_RS12740	COG0352	thiamine-phosphate diphosphorylase activity
AL038_RS12745	COG0564	pseudouridine synthase activity
AL038_RS12775	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
AL038_RS12785	COG3550	peptidyl-serine autophosphorylation
AL038_RS12795	COG4953	penicillin-binding protein 1C
AL038_RS12805	COG1858	cytochrome C peroxidase
AL038_RS12815	COG1408	metallophosphoesterase
AL038_RS12860	COG0742	ribosomal rna small subunit methyltransferase
AL038_RS12875	COG0667	Aldo Keto reductase
AL038_RS12915	COG0459	protein refolding
AL038_RS12920	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL038_RS12930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
AL038_RS12935	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
AL038_RS12945	COG0018	arginyl-trna synthetase
AL038_RS12950	COG1686	Belongs to the peptidase S11 family
AL038_RS12955	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
AL038_RS12960	COG2951	lytic endotransglycosylase activity
AL038_RS12965	COG0772	Belongs to the SEDS family
AL038_RS12970	COG4566	intracellular signal transduction
AL038_RS12980	COG0281	malic enzyme
AL038_RS12980	COG0280	phosphate acetyltransferase
AL038_RS12995	COG2205	protein histidine kinase activity
AL038_RS13000	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
AL038_RS13000	COG0543	2 iron, 2 sulfur cluster binding
AL038_RS13020	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
AL038_RS13030	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
AL038_RS13035	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
AL038_RS13040	COG0804	urea catabolic process
AL038_RS13045	COG0832	Belongs to the urease beta subunit family
AL038_RS13050	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL038_RS13050	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
AL038_RS13065	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
AL038_RS13075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
AL038_RS13110	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
AL038_RS13115	COG1040	competence protein
AL038_RS13140	COG5002	protein histidine kinase activity
AL038_RS13165	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL038_RS13170	COG0312	modulator of DNA gyrase
AL038_RS13185	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
AL038_RS13190	COG3977	Valine--pyruvate aminotransferase
AL038_RS13210	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL038_RS13215	COG0795	lipopolysaccharide-transporting ATPase activity
AL038_RS13225	COG1185	polyribonucleotide nucleotidyltransferase activity
AL038_RS13230	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
AL038_RS13245	COG0758	DNA mediated transformation
AL038_RS13250	COG2922	Belongs to the Smg family
AL038_RS13265	COG0367	asparagine synthase
AL038_RS13270	COG0438	transferase activity, transferring glycosyl groups
AL038_RS13275	COG3842	ATPase activity
AL038_RS13280	COG0745	RESPONSE REGULATOR receiver
AL038_RS13285	COG2205	protein histidine kinase activity
AL038_RS13295	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
AL038_RS13300	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
AL038_RS13310	COG0300	oxidoreductase activity
AL038_RS13320	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL038_RS13330	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
AL038_RS13330	COG2308	Evidence 4 Homologs of previously reported genes of
AL038_RS13365	COG2304	oxidoreductase activity
AL038_RS13390	COG3540	Alkaline phosphatase
AL038_RS13395	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL038_RS13400	COG0509	glycine decarboxylation via glycine cleavage system
AL038_RS13405	COG0404	The glycine cleavage system catalyzes the degradation of glycine
AL038_RS13415	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL038_RS13415	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
AL038_RS13420	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL038_RS13425	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
AL038_RS13445	COG2831	hemolysin activation secretion protein
AL038_RS13460	COG0009	L-threonylcarbamoyladenylate synthase
AL038_RS13465	COG1994	Peptidase M50
AL038_RS13470	COG0439	Biotin carboxylase
AL038_RS13475	COG0511	ligase activity, forming carbon-carbon bonds
AL038_RS13480	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
AL038_RS13485	COG2815	serine threonine protein kinase
AL038_RS13485	COG0515	serine threonine protein kinase
AL038_RS13500	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
AL038_RS13505	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
AL038_RS13510	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
AL038_RS13520	COG2274	protein secretion by the type I secretion system
AL038_RS13535	COG4166	transmembrane transport
AL038_RS13550	COG0737	Belongs to the 5'-nucleotidase family
AL038_RS13555	COG2205	protein histidine kinase activity
AL038_RS13570	COG0518	GMP synthase (glutamine-hydrolyzing) activity
AL038_RS13570	COG0519	Catalyzes the synthesis of GMP from XMP
AL038_RS13580	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
AL038_RS13605	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL038_RS13610	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL038_RS13635	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
AL038_RS13640	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
AL038_RS13650	COG0544	peptidyl-prolyl cis-trans isomerase activity
AL038_RS13665	COG0859	PFAM glycosyl transferase family 9
AL038_RS13675	COG2201	protein-glutamate methylesterase activity
AL038_RS13680	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
AL038_RS13730	COG3038	cytochrome b561
AL038_RS13745	COG0557	exoribonuclease II activity
AL038_RS13755	COG1450	Type ii and iii secretion system protein
AL038_RS13760	COG1459	type II secretion system
AL038_RS13765	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
AL038_RS13775	COG2369	cell adhesion
AL038_RS13780	COG0525	valine-tRNA ligase activity
AL038_RS13785	COG0183	Belongs to the thiolase family
AL038_RS13795	COG0205	6-phosphofructokinase activity
AL038_RS13810	COG0193	aminoacyl-tRNA hydrolase activity
AL038_RS13815	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
AL038_RS13820	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
AL038_RS13830	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
AL038_RS13835	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
AL038_RS13845	COG2814	Major facilitator Superfamily
AL038_RS13850	COG0203	ribosomal protein L17
AL038_RS13855	COG0202	RNA polymerase activity
AL038_RS13860	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
AL038_RS13865	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
AL038_RS13870	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
AL038_RS13875	COG0257	Belongs to the bacterial ribosomal protein bL36 family
AL038_RS13880	COG0201	protein transport
AL038_RS13885	COG0200	Binds to the 23S rRNA
AL038_RS13890	COG1841	ribosomal large subunit assembly
AL038_RS13900	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
AL038_RS13905	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
AL038_RS13915	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
AL038_RS13920	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
AL038_RS13925	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
AL038_RS13930	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
AL038_RS13935	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
AL038_RS13950	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
AL038_RS13960	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
AL038_RS13965	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
AL038_RS13970	COG0089	rRNA binding
AL038_RS13975	COG0088	Forms part of the polypeptide exit tunnel
AL038_RS13980	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
AL038_RS13985	COG0051	transcription antitermination factor activity, RNA binding
AL038_RS13990	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
AL038_RS13995	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
AL038_RS14000	COG0049	tRNA binding
AL038_RS14005	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
AL038_RS14010	COG4206	TonB-dependent receptor
AL038_RS14020	COG0612	Peptidase, M16
AL038_RS14025	COG0612	Peptidase, M16
AL038_RS14045	COG3956	TIGRFAM MazG family protein
AL038_RS14060	COG3850	Histidine kinase
AL038_RS14060	COG3437	response regulator, receiver
AL038_RS14060	COG2205	protein histidine kinase activity
AL038_RS14060	COG4999	Histidine kinase
AL038_RS14080	COG1858	cytochrome C peroxidase
AL038_RS14090	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
AL038_RS14095	COG3162	membrane
AL038_RS14100	COG0629	single-stranded DNA binding
AL038_RS14105	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
AL038_RS14105	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
AL038_RS14110	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL038_RS14115	COG0830	nickel cation binding
AL038_RS14120	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
AL038_RS14140	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
AL038_RS14170	COG2814	Major facilitator Superfamily
AL038_RS14195	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
AL038_RS14195	COG0116	Belongs to the methyltransferase superfamily
AL038_RS14200	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
AL038_RS14205	COG0729	surface antigen
AL038_RS14215	COG1074	ATP-dependent DNA helicase activity
AL038_RS14220	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
AL038_RS14225	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
AL038_RS14235	COG0218	Necessary for normal cell division and for the maintenance of normal septation
AL038_RS14240	COG1160	GTP binding
AL038_RS14250	COG0604	alcohol dehydrogenase
AL038_RS14275	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
AL038_RS14280	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
AL038_RS14285	COG0271	Belongs to the BolA IbaG family
AL038_RS14310	COG1216	Glycosyl transferase, family 2
AL038_RS14310	COG0438	transferase activity, transferring glycosyl groups
AL038_RS14330	COG3221	ABC-type phosphate phosphonate transport system periplasmic component
AL038_RS14335	COG5002	protein histidine kinase activity
AL038_RS14345	COG4536	flavin adenine dinucleotide binding
AL038_RS14350	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
AL038_RS14355	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
AL038_RS14380	COG0651	ATP synthesis coupled electron transport
AL038_RS14400	COG2204	response regulator
AL038_RS14410	COG4770	biotin carboxylase activity
AL038_RS14415	COG0306	phosphate transporter
AL038_RS14455	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
AL038_RS14465	COG0776	regulation of translation
AL038_RS14470	COG0072	phenylalanine-tRNA ligase activity
AL038_RS14480	COG0284	orotidine-5'-phosphate decarboxylase activity
AL038_RS14485	COG2956	Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane
AL038_RS14490	COG0776	regulation of translation
AL038_RS14500	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
AL038_RS14505	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
AL038_RS14510	COG0287	Prephenate dehydrogenase
AL038_RS14515	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
AL038_RS14520	COG2226	methyltransferase
AL038_RS14525	COG0037	tRNA processing
AL038_RS14530	COG1534	Rna-binding protein
AL038_RS14550	COG2239	Acts as a magnesium transporter
AL038_RS14575	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
AL038_RS14575	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
AL038_RS14640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL038_RS14650	COG0297	glycogen (starch) synthase activity
AL038_RS14655	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL038_RS14660	COG2226	methyltransferase
AL038_RS14675	COG1388	LysM domain
AL038_RS14675	COG4641	Protein conserved in bacteria
AL038_RS14690	COG0438	transferase activity, transferring glycosyl groups
AL038_RS14700	COG2226	methyltransferase
AL038_RS14765	COG0251	oxidation-reduction process
AL038_RS14785	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AL038_RS14785	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
AL038_RS14785	COG1703	isobutyryl-CoA mutase activity
AL038_RS14790	COG2205	protein histidine kinase activity
AL038_RS14790	COG0784	Response regulator, receiver
AL038_RS14795	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
AL038_RS14820	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
AL038_RS14830	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
AL038_RS14830	COG3261	NADH dehydrogenase
AL038_RS14840	COG1490	D-aminoacyl-tRNA deacylase activity
AL038_RS14850	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
AL038_RS14860	COG2350	Protein conserved in bacteria
AL038_RS14870	COG3088	subunit of a heme lyase
AL038_RS14875	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL038_RS14880	COG3842	ATPase activity
AL038_RS14885	COG0725	ABC transporter, periplasmic molybdate-binding protein
AL038_RS14890	COG4149	molybdate abc transporter
AL038_RS14910	COG5001	Diguanylate cyclase
AL038_RS14935	COG0028	Belongs to the TPP enzyme family
AL038_RS14945	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
AL038_RS14950	COG1183	phosphatidylcholine synthase activity
AL038_RS14970	COG2010	Cytochrome c
AL038_RS15040	COG0489	protein tyrosine kinase activity
AL038_RS15050	COG0424	maF-like protein
AL038_RS15055	COG1399	metal-binding, possibly nucleic acid-binding protein
AL038_RS15060	COG0333	Belongs to the bacterial ribosomal protein bL32 family
AL038_RS15065	COG0416	fatty acid biosynthetic process
AL038_RS15070	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
AL038_RS15080	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS15085	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
AL038_RS15090	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
AL038_RS15100	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
AL038_RS15110	COG0247	lactate metabolic process
AL038_RS15115	COG1592	Rubrerythrin
AL038_RS15125	COG2915	High frequency lysogenization protein hflD homolog
AL038_RS15140	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
AL038_RS15145	COG0131	Imidazoleglycerol-phosphate dehydratase
AL038_RS15150	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
AL038_RS15215	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
AL038_RS15245	COG2304	oxidoreductase activity
AL038_RS15250	COG0024	Methionine aminopeptidase
AL038_RS15255	COG0052	Belongs to the universal ribosomal protein uS2 family
AL038_RS15260	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
AL038_RS15265	COG0528	UMP kinase activity
AL038_RS15270	COG0233	cytoplasmic translational termination
AL038_RS15275	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
AL038_RS15285	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
AL038_RS15290	COG0750	zinc metalloprotease
AL038_RS15295	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
AL038_RS15305	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL038_RS15310	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
AL038_RS15315	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
AL038_RS15320	COG0268	Binds directly to 16S ribosomal RNA
AL038_RS15325	COG1229	Formylmethanofuran dehydrogenase subunit A
AL038_RS15330	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL038_RS15340	COG5635	Nacht domain
AL038_RS15340	COG2319	Wd-40 repeat
AL038_RS15350	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
AL038_RS15355	COG3850	Histidine kinase
AL038_RS15355	COG2205	protein histidine kinase activity
AL038_RS15355	COG4999	Histidine kinase
AL038_RS15355	COG3437	response regulator, receiver
AL038_RS15405	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
AL038_RS15440	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
AL038_RS15455	COG2717	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain
AL038_RS15460	COG0745	RESPONSE REGULATOR receiver
AL038_RS15475	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
AL038_RS15490	COG1120	ATPase activity
AL038_RS15535	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
AL038_RS15545	COG0261	This protein binds to 23S rRNA in the presence of protein L20
AL038_RS15560	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
AL038_RS15575	COG0658	competence protein
AL038_RS15575	COG2333	competence protein COMEC
AL038_RS15605	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
AL038_RS15610	COG0351	phosphomethylpyrimidine kinase
AL038_RS15615	COG4597	amino acid ABC transporter
AL038_RS15620	COG0765	amino acid transport
AL038_RS15630	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
AL038_RS15635	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
AL038_RS15650	COG2974	May be involved in recombination
AL038_RS15655	COG0598	Magnesium transport protein CorA
AL038_RS15680	COG2850	peptidyl-arginine hydroxylation
AL038_RS15690	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
AL038_RS15695	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
AL038_RS15700	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
AL038_RS15730	COG0316	Belongs to the HesB IscA family
AL038_RS15750	COG0633	Ferredoxin
AL038_RS15755	COG3321	synthase
AL038_RS15755	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS15755	COG0604	alcohol dehydrogenase
AL038_RS15760	COG3706	GGDEF domain
AL038_RS15760	COG2203	Gaf domain
AL038_RS15760	COG4251	negative regulation of phosphorylation
AL038_RS15760	COG5001	Diguanylate cyclase
AL038_RS15765	COG0714	Associated with various cellular activities
AL038_RS15775	COG2304	oxidoreductase activity
AL038_RS15780	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
AL038_RS15785	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
AL038_RS15805	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
AL038_RS15810	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
AL038_RS15850	COG2105	PFAM AIG2 family protein
AL038_RS15925	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
AL038_RS15965	COG0194	GDP metabolic process
AL038_RS15970	COG1561	YicC-like family, N-terminal region
AL038_RS15975	COG1477	protein flavinylation
AL038_RS15995	COG2425	protein containing a von Willebrand factor type A (vWA) domain
AL038_RS16005	COG0181	hydroxymethylbilane synthase activity
AL038_RS16015	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
AL038_RS16040	COG0745	RESPONSE REGULATOR receiver
AL038_RS16045	COG0642	Histidine kinase
AL038_RS16065	COG0492	ferredoxin-NADP+ reductase activity
AL038_RS16070	COG1674	ftsk spoiiie
AL038_RS16160	COG2205	protein histidine kinase activity
AL038_RS16165	COG3300	MHYT domain
AL038_RS16165	COG5001	Diguanylate cyclase
AL038_RS16170	COG2208	phosphoserine phosphatase activity
AL038_RS16170	COG2770	Histidine kinase
AL038_RS16180	COG0493	'glutamate synthase
AL038_RS16180	COG0543	2 iron, 2 sulfur cluster binding
AL038_RS16190	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
AL038_RS16190	COG4651	solute:proton antiporter activity
AL038_RS16215	COG1830	Aldolase
AL038_RS16220	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL038_RS16230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS16230	COG4191	Histidine kinase
AL038_RS16235	COG1278	Cold shock
AL038_RS16240	COG1278	Cold shock
AL038_RS16245	COG1278	Cold shock
AL038_RS16250	COG1278	Cold shock
AL038_RS16255	COG1278	Cold shock
AL038_RS16260	COG1278	Cold shock
AL038_RS16265	COG1278	Cold shock
AL038_RS16280	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
AL038_RS16290	COG1262	PFAM Formylglycine-generating sulfatase enzyme
AL038_RS16295	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
AL038_RS16325	COG0714	Associated with various cellular activities
AL038_RS16345	COG1366	Belongs to the anti-sigma-factor antagonist family
AL038_RS16365	COG0045	succinate-CoA ligase (ADP-forming) activity
AL038_RS16370	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
AL038_RS16375	COG0347	Belongs to the P(II) protein family
AL038_RS16380	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
AL038_RS16410	COG4969	Belongs to the N-Me-Phe pilin family
AL038_RS16445	COG0426	domain, Protein
AL038_RS16450	COG0633	Ferredoxin
AL038_RS16455	COG0633	Ferredoxin
AL038_RS16485	COG0542	response to heat
AL038_RS16505	COG0651	ATP synthesis coupled electron transport
AL038_RS16510	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
AL038_RS16520	COG0779	Required for maturation of 30S ribosomal subunits
AL038_RS16525	COG0195	Participates in both transcription termination and antitermination
AL038_RS16530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
AL038_RS16535	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
AL038_RS16540	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
AL038_RS16560	COG0784	Response regulator, receiver
AL038_RS16560	COG2205	protein histidine kinase activity
AL038_RS16560	COG5002	protein histidine kinase activity
AL038_RS16590	COG2815	serine threonine protein kinase
AL038_RS16590	COG0515	serine threonine protein kinase
AL038_RS16600	COG1977	Involved in sulfur transfer in the conversion of molybdopterin precursor Z to molybdopterin
AL038_RS16610	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
AL038_RS16615	COG2267	carboxylic ester hydrolase activity
AL038_RS16640	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
AL038_RS16645	COG1666	GTP binding
AL038_RS16650	COG0335	large ribosomal subunit rRNA binding
AL038_RS16660	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
AL038_RS16710	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
AL038_RS16730	COG0175	sulfate reduction
AL038_RS16740	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
AL038_RS16740	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
AL038_RS16745	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
AL038_RS16750	COG0501	Belongs to the peptidase M48B family
AL038_RS16815	COG0811	peptide transport
AL038_RS16820	COG0848	biopolymer transport protein
AL038_RS16825	COG1663	tetraacyldisaccharide 4'-kinase activity
AL038_RS16830	COG2835	tetraacyldisaccharide 4'-kinase activity
AL038_RS16835	COG0446	pyridine nucleotide-disulphide oxidoreductase
AL038_RS16870	COG4239	(ABC) transporter, permease
AL038_RS16875	COG4174	ABC transporter (Permease)
AL038_RS16880	COG1331	Highly conserved protein containing a thioredoxin domain
AL038_RS16885	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
AL038_RS16900	COG0459	protein refolding
AL038_RS16905	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
AL038_RS16910	COG0501	Belongs to the peptidase M48B family
AL038_RS16925	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
AL038_RS16945	COG4206	TonB-dependent receptor
AL038_RS16950	COG0668	transmembrane transport
AL038_RS16975	COG0772	Belongs to the SEDS family
AL038_RS17030	COG0735	belongs to the Fur family
AL038_RS17065	COG1872	DUF167
AL038_RS17090	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
AL038_RS17095	COG1702	phosphate starvation-inducible protein PhoH
AL038_RS17105	COG4535	Mg2 and Co2 transporter CorC
AL038_RS17140	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
AL038_RS17150	COG0714	Associated with various cellular activities
AL038_RS17160	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
AL038_RS17190	COG1335	isochorismatase
AL038_RS17205	COG2917	probably involved in intracellular septation
AL038_RS17210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
AL038_RS17220	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
AL038_RS17235	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
AL038_RS17270	COG0515	serine threonine protein kinase
AL038_RS17270	COG2815	serine threonine protein kinase
AL038_RS17275	COG1530	ribonuclease E activity
AL038_RS17280	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
AL038_RS17290	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
AL038_RS17295	COG0308	aminopeptidase N
AL038_RS17315	COG0784	Response regulator, receiver
AL038_RS17315	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS17315	COG2198	Histidine kinase
AL038_RS17315	COG2205	protein histidine kinase activity
AL038_RS17330	COG0369	Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L- cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH - FAD - FMN to the hemoprotein component
AL038_RS17345	COG0495	leucyl-tRNA aminoacylation
AL038_RS17360	COG0741	lytic transglycosylase activity
AL038_RS17375	COG1678	Uncharacterized ACR, COG1678
AL038_RS17380	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
AL038_RS17385	COG0540	Belongs to the ATCase OTCase family
AL038_RS17390	COG1509	lysine 2,3-aminomutase activity
AL038_RS17395	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
AL038_RS17400	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
AL038_RS17405	COG0232	Belongs to the dGTPase family. Type 2 subfamily
AL038_RS17410	COG0784	Response regulator, receiver
AL038_RS17410	COG5002	protein histidine kinase activity
AL038_RS17410	COG2205	protein histidine kinase activity
AL038_RS17455	COG3260	NADH ubiquinone oxidoreductase 20
AL038_RS17480	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
AL038_RS17480	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
AL038_RS17515	COG0137	argininosuccinate synthase activity
AL038_RS17545	COG1595	DNA-templated transcription, initiation
AL038_RS17560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
AL038_RS17560	COG2205	protein histidine kinase activity
AL038_RS17565	COG1446	asparaginase
AL038_RS17570	COG0154	amidase activity
AL038_RS17580	COG1077	Cell shape determining protein MreB Mrl
AL038_RS17585	COG1792	Involved in formation and maintenance of cell shape
AL038_RS17590	COG2891	Involved in formation of the rod shape of the cell. May also contribute to regulation of formation of penicillin-binding proteins
AL038_RS17595	COG0754	glutathionylspermidine amidase activity
AL038_RS17620	COG1028	Short-chain dehydrogenase reductase Sdr
AL038_RS17655	COG2204	response regulator
AL038_RS17660	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
AL038_RS17665	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
AL038_RS17675	COG0631	protein serine/threonine phosphatase activity
AL038_RS17685	COG4215	(ABC) transporter
AL038_RS17695	COG0424	maF-like protein
AL038_RS17700	COG0436	Aminotransferase
AL038_RS17725	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
AL038_RS17730	COG0326	Molecular chaperone. Has ATPase activity
AL038_RS17745	COG2258	MOSC domain
AL038_RS17750	COG0134	indole-3-glycerol-phosphate synthase activity
AL038_RS17780	COG2205	protein histidine kinase activity
AL038_RS17785	COG2154	pterin-4-alpha-carbinolamine dehydratase
AL038_RS17805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
AL038_RS17820	COG1804	L-carnitine dehydratase bile acid-inducible protein F
AL038_RS17845	COG0058	SHG alpha-glucan phosphorylase activity
AL038_RS17865	COG2224	Isocitrate lyase
AL038_RS17870	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
AL038_RS17880	COG0583	DNA-binding transcription factor activity
AL038_RS17890	COG0585	pseudouridine synthase activity
AL038_RS17895	COG0628	permease
AL038_RS17905	COG4771	TonB-dependent receptor
AL038_RS17910	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
AL038_RS17915	COG2208	phosphoserine phosphatase activity
AL038_RS17915	COG2770	Histidine kinase
AL038_RS17920	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
AL038_RS17925	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
AL038_RS17945	COG0174	glutamine synthetase
AL038_RS17950	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
AL038_RS17965	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
AL038_RS17985	COG4737	Cytotoxic translational repressor of toxin-antitoxin stability system
AL038_RS18025	COG1487	ribonuclease activity
AL038_RS18050	COG2079	MmgE PrpD family protein
AL038_RS18055	COG0372	Belongs to the citrate synthase family
AL038_RS18060	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
AL038_RS18080	COG0714	Associated with various cellular activities
AL038_RS18085	COG5002	protein histidine kinase activity
AL038_RS18085	COG5001	Diguanylate cyclase
AL038_RS18090	COG3842	ATPase activity
AL038_RS18095	COG1176	ABC-type spermidine putrescine transport system, permease component I
AL038_RS18100	COG1177	transmembrane transport
AL038_RS18135	COG0516	GMP reductase activity
AL038_RS18135	COG0517	IMP dehydrogenase activity
AL038_RS18150	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
AL038_RS18160	COG4974	Belongs to the 'phage' integrase family