locus-tag	class	description
BIND_RS00010	COG0268	Binds directly to 16S ribosomal RNA
BIND_RS00020	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BIND_RS00025	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BIND_RS00030	COG0632	four-way junction helicase activity
BIND_RS00040	COG0181	hydroxymethylbilane synthase activity
BIND_RS00050	COG1116	anion transmembrane transporter activity
BIND_RS00065	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BIND_RS00075	COG3511	phospholipase C
BIND_RS00075	COG3511	phospholipase C
BIND_RS00105	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BIND_RS00110	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BIND_RS00150	COG0300	oxidoreductase activity
BIND_RS00165	COG4221	oxidoreductase activity
BIND_RS00175	COG2267	carboxylic ester hydrolase activity
BIND_RS00190	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS00205	COG0300	oxidoreductase activity
BIND_RS00260	COG1376	ErfK ybiS ycfS ynhG family protein
BIND_RS00265	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BIND_RS00275	COG0583	DNA-binding transcription factor activity
BIND_RS00280	COG0492	ferredoxin-NADP+ reductase activity
BIND_RS00300	COG0408	coproporphyrinogen oxidase activity
BIND_RS00315	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BIND_RS00325	COG4303	Ethanolamine ammonia lyase large subunit
BIND_RS00330	COG4302	ethanolamine ammonia-lyase activity
BIND_RS00355	COG0175	sulfate reduction
BIND_RS00360	COG0247	lactate metabolic process
BIND_RS00395	COG0436	Aminotransferase
BIND_RS00400	COG0840	transmembrane signaling receptor activity
BIND_RS00425	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BIND_RS00450	COG1902	pentaerythritol trinitrate reductase activity
BIND_RS00465	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BIND_RS00485	COG2917	probably involved in intracellular septation
BIND_RS00490	COG2945	thiolester hydrolase activity
BIND_RS00495	COG1104	cysteine desulfurase activity
BIND_RS00500	COG0719	Fe-S assembly protein
BIND_RS00505	COG0396	ATPase activity
BIND_RS00510	COG0719	Fe-S assembly protein
BIND_RS00515	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BIND_RS00520	COG2151	metal-sulfur cluster biosynthetic enzyme
BIND_RS00525	COG0316	Belongs to the HesB IscA family
BIND_RS00530	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BIND_RS00535	COG2814	Major facilitator Superfamily
BIND_RS00540	COG0513	Belongs to the DEAD box helicase family
BIND_RS00545	COG0672	)-iron permease
BIND_RS00565	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BIND_RS00570	COG3909	cytochrome
BIND_RS00580	COG0438	transferase activity, transferring glycosyl groups
BIND_RS00590	COG1396	sequence-specific DNA binding
BIND_RS00610	COG0022	dehydrogenase e1 component
BIND_RS00615	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BIND_RS00620	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIND_RS00635	COG0351	phosphomethylpyrimidine kinase
BIND_RS00650	COG0443	Heat shock 70 kDa protein
BIND_RS00655	COG0484	heat shock protein binding
BIND_RS00660	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BIND_RS00670	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BIND_RS00675	COG2255	four-way junction helicase activity
BIND_RS00690	COG1216	Glycosyl transferase, family 2
BIND_RS00700	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BIND_RS00715	COG2989	Protein conserved in bacteria
BIND_RS00745	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BIND_RS00750	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BIND_RS00765	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BIND_RS00770	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BIND_RS00780	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BIND_RS00785	COG0723	plastoquinol--plastocyanin reductase activity
BIND_RS00790	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BIND_RS00790	COG2857	Cytochrome c1
BIND_RS00795	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BIND_RS00795	COG2857	Cytochrome c1
BIND_RS00800	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BIND_RS00805	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BIND_RS00810	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BIND_RS00815	COG0546	phosphoglycolate phosphatase activity
BIND_RS00840	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BIND_RS00850	COG0778	Nitroreductase
BIND_RS00855	COG2030	dehydratase
BIND_RS00855	COG1012	belongs to the aldehyde dehydrogenase family
BIND_RS00860	COG0012	GTP binding
BIND_RS00865	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BIND_RS00880	COG1454	alcohol dehydrogenase
BIND_RS00895	COG1070	Carbohydrate kinase
BIND_RS00905	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BIND_RS00910	COG0803	Belongs to the bacterial solute-binding protein 9 family
BIND_RS00920	COG1301	dicarboxylic acid transport
BIND_RS00925	COG4191	Histidine kinase
BIND_RS00930	COG2204	response regulator
BIND_RS00980	COG3384	dioxygenase
BIND_RS00995	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BIND_RS01005	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BIND_RS01035	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BIND_RS01040	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BIND_RS01045	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BIND_RS01050	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BIND_RS01055	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BIND_RS01075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BIND_RS01080	COG0066	3-isopropylmalate dehydratase activity
BIND_RS01085	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BIND_RS01090	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BIND_RS01095	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BIND_RS01100	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BIND_RS01105	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BIND_RS01125	COG0495	leucyl-tRNA aminoacylation
BIND_RS01170	COG0848	biopolymer transport protein
BIND_RS01180	COG3128	pkhd-type hydroxylase
BIND_RS01190	COG4773	Receptor
BIND_RS01205	COG1072	(Pantothenic acid kinase))
BIND_RS01210	COG0140	phosphoribosyl-ATP diphosphatase activity
BIND_RS01215	COG0107	imidazoleglycerol-phosphate synthase activity
BIND_RS01230	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BIND_RS01235	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BIND_RS01245	COG0131	Imidazoleglycerol-phosphate dehydratase
BIND_RS01250	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BIND_RS01255	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BIND_RS01270	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BIND_RS01275	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BIND_RS01280	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BIND_RS01290	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BIND_RS01305	COG0254	rRNA binding
BIND_RS01310	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BIND_RS01325	COG1733	regulation of RNA biosynthetic process
BIND_RS01335	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BIND_RS01340	COG1648	precorrin-2 dehydrogenase activity
BIND_RS01340	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BIND_RS01355	COG0823	Involved in the tonB-independent uptake of proteins
BIND_RS01370	COG0811	peptide transport
BIND_RS01380	COG3293	Transposase
BIND_RS01390	COG1309	transcriptional regulator
BIND_RS01395	COG2267	carboxylic ester hydrolase activity
BIND_RS01400	COG0824	Thioesterase
BIND_RS01430	COG0412	Dienelactone hydrolase
BIND_RS01440	COG1215	transferase activity, transferring glycosyl groups
BIND_RS01445	COG0300	oxidoreductase activity
BIND_RS01460	COG3546	catalase activity
BIND_RS01480	COG0556	nucleotide-excision repair
BIND_RS01495	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BIND_RS01500	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BIND_RS01505	COG0750	zinc metalloprotease
BIND_RS01510	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BIND_RS01520	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BIND_RS01525	COG0233	cytoplasmic translational termination
BIND_RS01530	COG0528	UMP kinase activity
BIND_RS01545	COG2197	response regulator
BIND_RS01560	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BIND_RS01565	COG0287	Prephenate dehydrogenase
BIND_RS01570	COG0583	DNA-binding transcription factor activity
BIND_RS01605	COG2132	Multicopper oxidase
BIND_RS01620	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BIND_RS01630	COG1959	2 iron, 2 sulfur cluster binding
BIND_RS01650	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BIND_RS01680	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BIND_RS01690	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BIND_RS01700	COG1968	undecaprenyl-diphosphatase activity
BIND_RS01710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BIND_RS01725	COG3794	PFAM blue (type 1) copper domain protein
BIND_RS01740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BIND_RS01750	COG0217	transcriptional regulatory protein
BIND_RS01755	COG0625	glutathione transferase activity
BIND_RS01760	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BIND_RS01765	COG0564	pseudouridine synthase activity
BIND_RS01770	COG1132	(ABC) transporter
BIND_RS01795	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BIND_RS01810	COG1686	Belongs to the peptidase S11 family
BIND_RS01820	COG0523	cobalamin synthesis protein
BIND_RS01825	COG0180	Tryptophanyl-tRNA synthetase
BIND_RS01830	COG0552	protein localization to endoplasmic reticulum
BIND_RS01835	COG2884	Cell division ATP-binding protein ftsE
BIND_RS01845	COG0784	Response regulator, receiver
BIND_RS01845	COG4191	Histidine kinase
BIND_RS01890	COG1201	RNA secondary structure unwinding
BIND_RS01910	COG0776	regulation of translation
BIND_RS01920	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BIND_RS01925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BIND_RS01930	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BIND_RS01945	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BIND_RS01965	COG1492	cobalamin metabolic process
BIND_RS01970	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BIND_RS01995	COG3604	Transcriptional regulator
BIND_RS02000	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BIND_RS02015	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BIND_RS02035	COG5554	nitrogen fixation
BIND_RS02045	COG1104	cysteine desulfurase activity
BIND_RS02050	COG5554	nitrogen fixation
BIND_RS02060	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BIND_RS02080	COG2346	COG2346, Truncated hemoglobins
BIND_RS02095	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BIND_RS02100	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BIND_RS02105	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BIND_RS02115	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BIND_RS02120	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BIND_RS02125	COG0739	heme binding
BIND_RS02145	COG0142	geranyltranstransferase activity
BIND_RS02155	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BIND_RS02170	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BIND_RS02180	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BIND_RS02185	COG2226	methyltransferase
BIND_RS02200	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BIND_RS02205	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BIND_RS02210	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BIND_RS02220	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BIND_RS02230	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BIND_RS02265	COG0400	carboxylic ester hydrolase activity
BIND_RS02300	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BIND_RS02305	COG1376	ErfK ybiS ycfS ynhG family protein
BIND_RS02310	COG1217	gtp-binding protein TYPA
BIND_RS02315	COG1283	sodium-dependent phosphate transmembrane transporter activity
BIND_RS02320	COG0363	glucosamine-6-phosphate deaminase activity
BIND_RS02325	COG0561	phosphatase activity
BIND_RS02330	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BIND_RS02335	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BIND_RS02350	COG0625	glutathione transferase activity
BIND_RS02385	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BIND_RS02405	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BIND_RS02415	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BIND_RS02420	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BIND_RS02425	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BIND_RS02440	COG5420	small protein containing a coiled-coil domain
BIND_RS02445	COG3383	formate dehydrogenase (NAD+) activity
BIND_RS02460	COG0316	Belongs to the HesB IscA family
BIND_RS02480	COG2086	electron transfer activity
BIND_RS02485	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BIND_RS02490	COG0644	oxidoreductase
BIND_RS02515	COG0588	phosphoglycerate mutase activity
BIND_RS02520	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BIND_RS02525	COG0242	peptide deformylase activity
BIND_RS02530	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BIND_RS02535	COG0101	tRNA pseudouridine synthase activity
BIND_RS02570	COG0543	2 iron, 2 sulfur cluster binding
BIND_RS02590	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BIND_RS02605	COG0071	Belongs to the small heat shock protein (HSP20) family
BIND_RS02615	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BIND_RS02635	COG0463	Glycosyl transferase, family 2
BIND_RS02635	COG1216	Glycosyl transferase, family 2
BIND_RS02655	COG0242	peptide deformylase activity
BIND_RS02660	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BIND_RS02665	COG1960	acyl-CoA dehydrogenase activity
BIND_RS02670	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BIND_RS02675	COG0583	DNA-binding transcription factor activity
BIND_RS02725	COG0502	Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical- based mechanism
BIND_RS02735	COG1253	flavin adenine dinucleotide binding
BIND_RS02750	COG1994	Peptidase M50
BIND_RS02755	COG2317	Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues
BIND_RS02760	COG3034	peptidoglycan biosynthetic process
BIND_RS02765	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BIND_RS02775	COG1278	Cold shock
BIND_RS02780	COG0583	DNA-binding transcription factor activity
BIND_RS02790	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BIND_RS02800	COG1116	anion transmembrane transporter activity
BIND_RS02800	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BIND_RS02805	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BIND_RS02810	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BIND_RS02825	COG3119	arylsulfatase activity
BIND_RS02835	COG2264	protein methyltransferase activity
BIND_RS02845	COG1139	Iron-sulfur cluster binding protein
BIND_RS02850	COG0247	lactate metabolic process
BIND_RS02855	COG1620	l-lactate permease
BIND_RS02870	COG2610	gluconate transmembrane transporter activity
BIND_RS02885	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BIND_RS02890	COG1137	ATPase activity
BIND_RS02910	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BIND_RS02915	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIND_RS02920	COG2813	Specifically methylates the guanine in position
BIND_RS02920	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIND_RS02930	COG0488	(ABC) transporter
BIND_RS02950	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS02955	COG4221	oxidoreductase activity
BIND_RS02960	COG0025	NhaP-type Na H and K H
BIND_RS02965	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BIND_RS02985	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BIND_RS02990	COG3178	'Phosphotransferase
BIND_RS03000	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BIND_RS03010	COG1215	transferase activity, transferring glycosyl groups
BIND_RS03045	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BIND_RS03090	COG2373	Large extracellular alpha-helical protein
BIND_RS03095	COG4953	penicillin-binding protein 1C
BIND_RS03135	COG2801	Transposase and inactivated derivatives
BIND_RS03165	COG1024	Enoyl-CoA hydratase
BIND_RS03175	COG1024	Enoyl-CoA hydratase
BIND_RS03180	COG1960	acyl-CoA dehydrogenase activity
BIND_RS03190	COG0583	DNA-binding transcription factor activity
BIND_RS03195	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS03205	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BIND_RS03215	COG1609	Transcriptional regulator
BIND_RS03220	COG3265	gluconokinase activity
BIND_RS03230	COG0477	Major facilitator Superfamily
BIND_RS03240	COG0800	Aldolase
BIND_RS03245	COG0469	pyruvate kinase activity
BIND_RS03345	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BIND_RS03355	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BIND_RS03365	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BIND_RS03370	COG1902	pentaerythritol trinitrate reductase activity
BIND_RS03380	COG1285	pathogenesis
BIND_RS03385	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BIND_RS03400	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BIND_RS03405	COG1278	Cold shock
BIND_RS03425	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BIND_RS03430	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BIND_RS03435	COG5328	Belongs to the UPF0262 family
BIND_RS03440	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BIND_RS03460	COG0488	(ABC) transporter
BIND_RS03480	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BIND_RS03510	COG2001	Belongs to the MraZ family
BIND_RS03515	COG0275	rRNA processing
BIND_RS03530	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BIND_RS03540	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BIND_RS03545	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BIND_RS03555	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BIND_RS03560	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BIND_RS03565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BIND_RS03570	COG1181	Belongs to the D-alanine--D-alanine ligase family
BIND_RS03580	COG0849	cell division
BIND_RS03585	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BIND_RS03590	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BIND_RS03605	COG0596	Alpha beta hydrolase
BIND_RS03625	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BIND_RS03640	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BIND_RS03645	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BIND_RS03655	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BIND_RS03670	COG1051	belongs to the nudix hydrolase family
BIND_RS03680	COG1678	Uncharacterized ACR, COG1678
BIND_RS03695	COG0612	Peptidase, M16
BIND_RS03705	COG3346	SURF1 family
BIND_RS03720	COG3175	Exerts its effect at some terminal stage of cytochrome c oxidase synthesis, probably by being involved in the insertion of the copper B into subunit I
BIND_RS03725	COG0109	protoheme IX farnesyltransferase activity
BIND_RS03730	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BIND_RS03750	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BIND_RS03755	COG0509	glycine decarboxylation via glycine cleavage system
BIND_RS03760	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BIND_RS03765	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BIND_RS03780	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BIND_RS03785	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BIND_RS03790	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BIND_RS03795	COG0356	it plays a direct role in the translocation of protons across the membrane
BIND_RS03805	COG1196	nuclear chromosome segregation
BIND_RS03820	COG1194	a g-specific adenine glycosylase
BIND_RS03835	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BIND_RS03860	COG3161	chorismate lyase activity
BIND_RS03865	COG1238	metal cluster binding
BIND_RS03875	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BIND_RS03910	COG0427	acetyl-CoA hydrolase
BIND_RS03920	COG1351	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor, and NAD(P)H and FADH(2) as the reductant
BIND_RS03950	COG1012	belongs to the aldehyde dehydrogenase family
BIND_RS03955	COG2264	protein methyltransferase activity
BIND_RS03960	COG3047	cAMP biosynthetic process
BIND_RS03965	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BIND_RS03970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BIND_RS04010	COG0210	DNA helicase
BIND_RS04015	COG0667	Aldo Keto reductase
BIND_RS04025	COG0583	DNA-binding transcription factor activity
BIND_RS04045	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BIND_RS04055	COG0750	zinc metalloprotease
BIND_RS04095	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BIND_RS04110	COG1612	heme a metabolic process
BIND_RS04115	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIND_RS04120	COG1129	ABC transporter
BIND_RS04120	COG0842	Transport permease protein
BIND_RS04125	COG0842	Transport permease protein
BIND_RS04135	COG0132	Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8-diaminopelargonic acid (DAPA) to form an ureido ring
BIND_RS04140	COG0156	8-amino-7-oxononanoate synthase activity
BIND_RS04145	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BIND_RS04180	COG0542	response to heat
BIND_RS04190	COG2890	protein-(glutamine-N5) methyltransferase activity
BIND_RS04195	COG0326	Molecular chaperone. Has ATPase activity
BIND_RS04205	COG0670	Belongs to the BI1 family
BIND_RS04215	COG4181	ATPase activity
BIND_RS04225	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BIND_RS04230	COG2124	cytochrome p450
BIND_RS04255	COG0438	transferase activity, transferring glycosyl groups
BIND_RS04260	COG3206	protein involved in exopolysaccharide biosynthesis
BIND_RS04260	COG0489	protein tyrosine kinase activity
BIND_RS04270	COG0438	transferase activity, transferring glycosyl groups
BIND_RS04275	COG0297	glycogen (starch) synthase activity
BIND_RS04325	COG0308	aminopeptidase N
BIND_RS04345	COG0346	lactoylglutathione lyase activity
BIND_RS04350	COG0142	geranyltranstransferase activity
BIND_RS04365	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BIND_RS04385	COG0494	nUDIX hydrolase
BIND_RS04390	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BIND_RS04400	COG1472	Belongs to the glycosyl hydrolase 3 family
BIND_RS04415	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BIND_RS04420	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BIND_RS04445	COG0667	Aldo Keto reductase
BIND_RS04455	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
BIND_RS04465	COG0546	phosphoglycolate phosphatase activity
BIND_RS04475	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BIND_RS04500	COG2989	Protein conserved in bacteria
BIND_RS04520	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BIND_RS04525	COG3605	phosphoenolpyruvate-protein phosphotransferase activity
BIND_RS04530	COG0527	aspartate kinase activity
BIND_RS04545	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BIND_RS04550	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BIND_RS04580	COG1309	transcriptional regulator
BIND_RS04590	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIND_RS04600	COG1902	pentaerythritol trinitrate reductase activity
BIND_RS04615	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BIND_RS04635	COG2814	Major facilitator Superfamily
BIND_RS04640	COG0667	Aldo Keto reductase
BIND_RS04650	COG0483	inositol monophosphate 1-phosphatase activity
BIND_RS04690	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BIND_RS04710	COG2267	carboxylic ester hydrolase activity
BIND_RS04725	COG1982	Orn Lys Arg decarboxylase major
BIND_RS04740	COG1530	ribonuclease E activity
BIND_RS04740	COG1530	ribonuclease E activity
BIND_RS04745	COG0860	N-Acetylmuramoyl-L-alanine amidase
BIND_RS04750	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BIND_RS04755	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BIND_RS04765	COG0246	Mannitol dehydrogenase
BIND_RS04770	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BIND_RS04785	COG1132	(ABC) transporter
BIND_RS04790	COG3698	Phosphodiester glycosidase
BIND_RS04795	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BIND_RS04795	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BIND_RS04805	COG0123	including yeast histone deacetylase and acetoin utilization protein
BIND_RS04810	COG1408	metallophosphoesterase
BIND_RS04825	COG0604	alcohol dehydrogenase
BIND_RS04835	COG1733	regulation of RNA biosynthetic process
BIND_RS04840	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BIND_RS04880	COG1902	pentaerythritol trinitrate reductase activity
BIND_RS04885	COG1309	transcriptional regulator
BIND_RS04925	COG2814	Major facilitator Superfamily
BIND_RS04940	COG0376	Bifunctional enzyme with both catalase and broad- spectrum peroxidase activity
BIND_RS04945	COG0745	RESPONSE REGULATOR receiver
BIND_RS04950	COG0784	Response regulator, receiver
BIND_RS04950	COG2198	Histidine kinase
BIND_RS04950	COG5002	protein histidine kinase activity
BIND_RS05000	COG2140	Oxalate decarboxylase
BIND_RS05005	COG2223	nitrite transmembrane transporter activity
BIND_RS05015	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BIND_RS05025	COG3383	formate dehydrogenase (NAD+) activity
BIND_RS05035	COG0303	'Molybdopterin
BIND_RS05040	COG0746	molybdenum cofactor guanylyltransferase activity
BIND_RS05045	COG1526	Required for formate dehydrogenase (FDH) activity. Acts as a sulfur carrier protein that transfers sulfur from IscS to the molybdenum cofactor prior to its insertion into FDH
BIND_RS05055	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
BIND_RS05070	COG1862	Preprotein translocase
BIND_RS05075	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BIND_RS05100	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BIND_RS05105	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BIND_RS05115	COG0612	Peptidase, M16
BIND_RS05120	COG0612	Peptidase, M16
BIND_RS05125	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BIND_RS05135	COG0151	Belongs to the GarS family
BIND_RS05150	COG1733	regulation of RNA biosynthetic process
BIND_RS05155	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BIND_RS05160	COG1393	Belongs to the ArsC family
BIND_RS05165	COG0071	Belongs to the small heat shock protein (HSP20) family
BIND_RS05210	COG0277	FAD linked oxidase domain protein
BIND_RS05225	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BIND_RS05230	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BIND_RS05230	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BIND_RS05235	COG2942	2-epimerase
BIND_RS05245	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BIND_RS05255	COG0235	Class ii aldolase
BIND_RS05260	COG0717	Belongs to the dCTP deaminase family
BIND_RS05270	COG2967	ApaG domain
BIND_RS05280	COG0804	urea catabolic process
BIND_RS05290	COG2337	Toxic component of a toxin-antitoxin (TA) module
BIND_RS05310	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BIND_RS05315	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BIND_RS05320	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BIND_RS05335	COG0779	Required for maturation of 30S ribosomal subunits
BIND_RS05340	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BIND_RS05360	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BIND_RS05365	COG1702	phosphate starvation-inducible protein PhoH
BIND_RS05370	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BIND_RS05375	COG4535	Mg2 and Co2 transporter CorC
BIND_RS05380	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BIND_RS05385	COG1396	sequence-specific DNA binding
BIND_RS05390	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BIND_RS05395	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BIND_RS05420	COG0167	dihydroorotate dehydrogenase activity
BIND_RS05435	COG1793	dna ligase
BIND_RS05455	COG2226	methyltransferase
BIND_RS05460	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BIND_RS05470	COG5310	Homospermidine synthase
BIND_RS05485	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BIND_RS05490	COG1214	PFAM Peptidase M22, glycoprotease
BIND_RS05490	COG0456	acetyltransferase
BIND_RS05530	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BIND_RS05540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BIND_RS05545	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BIND_RS05555	COG0789	Transcriptional regulator
BIND_RS05565	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BIND_RS05570	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BIND_RS05575	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BIND_RS05580	COG2205	protein histidine kinase activity
BIND_RS05585	COG0745	RESPONSE REGULATOR receiver
BIND_RS05600	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BIND_RS05640	COG0156	8-amino-7-oxononanoate synthase activity
BIND_RS05650	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS05650	COG0604	alcohol dehydrogenase
BIND_RS05650	COG3321	synthase
BIND_RS05685	COG0640	Transcriptional regulator
BIND_RS05690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BIND_RS05700	COG0432	Pfam Uncharacterised protein family UPF0047
BIND_RS05710	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS05735	COG1546	Belongs to the CinA family
BIND_RS05735	COG1058	Belongs to the CinA family
BIND_RS05740	COG2236	Acts on guanine, xanthine and to a lesser extent hypoxanthine
BIND_RS05750	COG0538	isocitrate dehydrogenase activity
BIND_RS05760	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BIND_RS05765	COG0489	protein tyrosine kinase activity
BIND_RS05765	COG3206	protein involved in exopolysaccharide biosynthesis
BIND_RS05770	COG2226	methyltransferase
BIND_RS05780	COG0512	Glutamine amidotransferase of anthranilate synthase
BIND_RS05785	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BIND_RS05790	COG1040	competence protein
BIND_RS05800	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BIND_RS05810	COG1064	alcohol dehydrogenase
BIND_RS05840	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BIND_RS05850	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BIND_RS05885	COG0375	protein maturation
BIND_RS05895	COG2204	response regulator
BIND_RS05930	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIND_RS05935	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIND_RS05945	COG1722	exodeoxyribonuclease VII activity
BIND_RS05950	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS05960	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BIND_RS05970	COG0519	Catalyzes the synthesis of GMP from XMP
BIND_RS05985	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BIND_RS05990	COG4133	protoheme IX ABC transporter activity
BIND_RS05995	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BIND_RS06000	COG0473	3-isopropylmalate dehydrogenase activity
BIND_RS06020	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BIND_RS06025	COG0288	reversible hydration of carbon dioxide
BIND_RS06030	COG2301	Belongs to the HpcH HpaI aldolase family
BIND_RS06055	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BIND_RS06055	COG0662	Cupin 2, conserved barrel domain protein
BIND_RS06060	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BIND_RS06075	COG2885	chlorophyll binding
BIND_RS06075	COG3047	cAMP biosynthetic process
BIND_RS06080	COG0052	Belongs to the universal ribosomal protein uS2 family
BIND_RS06085	COG0667	Aldo Keto reductase
BIND_RS06115	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BIND_RS06135	COG0113	porphobilinogen synthase activity
BIND_RS06140	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BIND_RS06145	COG0435	Glutathione S-transferase
BIND_RS06155	COG0784	Response regulator, receiver
BIND_RS06170	COG0187	DNA topoisomerase II activity
BIND_RS06175	COG0174	glutamine synthetase
BIND_RS06180	COG0347	Belongs to the P(II) protein family
BIND_RS06190	COG2897	thiosulfate sulfurtransferase activity
BIND_RS06210	COG4221	oxidoreductase activity
BIND_RS06220	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS06225	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BIND_RS06230	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BIND_RS06230	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BIND_RS06240	COG0025	NhaP-type Na H and K H
BIND_RS06255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BIND_RS06260	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BIND_RS06265	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BIND_RS06290	COG1570	exodeoxyribonuclease VII activity
BIND_RS06310	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BIND_RS06330	COG4977	sequence-specific DNA binding
BIND_RS06335	COG1335	isochorismatase
BIND_RS06355	COG0596	Alpha beta hydrolase
BIND_RS06365	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BIND_RS06390	COG1643	Atp-dependent helicase
BIND_RS06400	COG3158	transport of potassium into the cell
BIND_RS06405	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BIND_RS06410	COG0659	secondary active sulfate transmembrane transporter activity
BIND_RS06425	COG0745	RESPONSE REGULATOR receiver
BIND_RS06435	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BIND_RS06440	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BIND_RS06450	COG0753	catalase activity
BIND_RS06460	COG0137	argininosuccinate synthase activity
BIND_RS06470	COG0667	Aldo Keto reductase
BIND_RS06475	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS06505	COG1607	acyl-coa hydrolase
BIND_RS06510	COG1331	Highly conserved protein containing a thioredoxin domain
BIND_RS06515	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BIND_RS06520	COG0445	tRNA wobble uridine modification
BIND_RS06525	COG0357	Ribosomal RNA small subunit methyltransferase G
BIND_RS06530	COG0138	bifunctional purine biosynthesis protein purh
BIND_RS06540	COG0194	GDP metabolic process
BIND_RS06545	COG1561	YicC-like family, N-terminal region
BIND_RS06550	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BIND_RS06555	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BIND_RS06575	COG0628	permease
BIND_RS06590	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIND_RS06600	COG0154	amidase activity
BIND_RS06620	COG3038	cytochrome b561
BIND_RS06650	COG0546	phosphoglycolate phosphatase activity
BIND_RS06655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BIND_RS06665	COG0546	phosphoglycolate phosphatase activity
BIND_RS06675	COG0386	Belongs to the glutathione peroxidase family
BIND_RS06680	COG1247	-acetyltransferase
BIND_RS06685	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BIND_RS06690	COG4770	biotin carboxylase activity
BIND_RS06695	COG1621	beta-fructofuranosidase activity
BIND_RS06700	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BIND_RS06705	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BIND_RS06710	COG1254	Belongs to the acylphosphatase family
BIND_RS06730	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BIND_RS06735	COG0196	riboflavin kinase activity
BIND_RS06750	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BIND_RS06765	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BIND_RS06780	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BIND_RS06805	COG0511	ligase activity, forming carbon-carbon bonds
BIND_RS06810	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BIND_RS06820	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BIND_RS06825	COG0081	regulation of translation
BIND_RS06830	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BIND_RS06835	COG0222	ribosome binding
BIND_RS06840	COG0085	RNA polymerase activity
BIND_RS06845	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BIND_RS06850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BIND_RS06855	COG0049	tRNA binding
BIND_RS06860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BIND_RS06865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BIND_RS06870	COG0051	transcription antitermination factor activity, RNA binding
BIND_RS06875	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BIND_RS06880	COG0088	Forms part of the polypeptide exit tunnel
BIND_RS06885	COG0089	rRNA binding
BIND_RS06890	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BIND_RS06895	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BIND_RS06900	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BIND_RS06905	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BIND_RS06910	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BIND_RS06915	COG0255	Belongs to the universal ribosomal protein uL29 family
BIND_RS06920	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BIND_RS06925	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BIND_RS06930	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BIND_RS06935	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BIND_RS06940	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BIND_RS06945	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BIND_RS06950	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BIND_RS06955	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BIND_RS06960	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BIND_RS06965	COG1841	ribosomal large subunit assembly
BIND_RS06970	COG0200	Binds to the 23S rRNA
BIND_RS06980	COG0563	adenylate kinase activity
BIND_RS06985	COG1959	2 iron, 2 sulfur cluster binding
BIND_RS06995	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BIND_RS07000	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BIND_RS07005	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BIND_RS07020	COG0151	Belongs to the GarS family
BIND_RS07035	COG1335	isochorismatase
BIND_RS07045	COG1494	fructose-1,6-bisphosphatase
BIND_RS07050	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BIND_RS07070	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIND_RS07080	COG2610	gluconate transmembrane transporter activity
BIND_RS07085	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BIND_RS07120	COG0708	Exodeoxyribonuclease III
BIND_RS07135	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BIND_RS07150	COG0583	DNA-binding transcription factor activity
BIND_RS07155	COG0372	Belongs to the citrate synthase family
BIND_RS07160	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BIND_RS07180	COG0505	Belongs to the CarA family
BIND_RS07200	COG0134	indole-3-glycerol-phosphate synthase activity
BIND_RS07205	COG0315	cyclic pyranopterin monophosphate synthase activity
BIND_RS07210	COG0303	'Molybdopterin
BIND_RS07215	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BIND_RS07230	COG1192	Involved in chromosome partitioning
BIND_RS07265	COG3220	belongs to the UPF0276 family
BIND_RS07290	COG2367	Beta-lactamase
BIND_RS07300	COG0583	DNA-binding transcription factor activity
BIND_RS07330	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BIND_RS07345	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
BIND_RS07350	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BIND_RS07360	COG0149	triose-phosphate isomerase activity
BIND_RS07370	COG0504	CTP synthase activity
BIND_RS07380	COG0583	DNA-binding transcription factor activity
BIND_RS07390	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS07400	COG0583	DNA-binding transcription factor activity
BIND_RS07415	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BIND_RS07430	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BIND_RS07445	COG0148	phosphopyruvate hydratase activity
BIND_RS07455	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS07465	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS07475	COG1917	Cupin 2, conserved barrel domain protein
BIND_RS07475	COG4977	sequence-specific DNA binding
BIND_RS07495	COG0596	Alpha beta hydrolase
BIND_RS07500	COG1063	alcohol dehydrogenase
BIND_RS07505	COG1309	transcriptional regulator
BIND_RS07515	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS07520	COG0583	DNA-binding transcription factor activity
BIND_RS07525	COG4453	Protein conserved in bacteria
BIND_RS07545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BIND_RS07555	COG1182	Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity
BIND_RS07565	COG1733	regulation of RNA biosynthetic process
BIND_RS07635	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BIND_RS07640	COG0508	dehydrogenase complex catalyzes the overall conversion of
BIND_RS07640	COG0022	dehydrogenase e1 component
BIND_RS07645	COG0508	dehydrogenase complex catalyzes the overall conversion of
BIND_RS07650	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BIND_RS07655	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BIND_RS07670	COG2867	negative regulation of translational initiation
BIND_RS07680	COG1546	Belongs to the CinA family
BIND_RS07680	COG1058	Belongs to the CinA family
BIND_RS07690	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BIND_RS07690	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BIND_RS07695	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BIND_RS07705	COG2204	response regulator
BIND_RS07710	COG5000	phosphorelay sensor kinase activity
BIND_RS07715	COG2204	response regulator
BIND_RS07730	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BIND_RS07735	COG1923	regulation of RNA biosynthetic process
BIND_RS07740	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BIND_RS07745	COG3956	TIGRFAM MazG family protein
BIND_RS07750	COG1278	Cold shock
BIND_RS07760	COG1522	sequence-specific DNA binding
BIND_RS07775	COG0084	hydrolase, TatD family'
BIND_RS07785	COG0470	DNA polymerase III
BIND_RS07790	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BIND_RS07795	COG1686	Belongs to the peptidase S11 family
BIND_RS07885	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BIND_RS07890	COG0028	Belongs to the TPP enzyme family
BIND_RS07905	COG2192	nodulation
BIND_RS07915	COG0134	indole-3-glycerol-phosphate synthase activity
BIND_RS07920	COG2032	superoxide dismutase activity
BIND_RS07935	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BIND_RS07940	COG1376	ErfK ybiS ycfS ynhG family protein
BIND_RS07955	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BIND_RS07965	COG0686	Belongs to the AlaDH PNT family
BIND_RS07970	COG0778	Nitroreductase
BIND_RS07975	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BIND_RS07980	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BIND_RS07995	COG0302	gtp cyclohydrolase
BIND_RS08005	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BIND_RS08010	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
BIND_RS08010	COG0617	tRNA 3'-terminal CCA addition
BIND_RS08010	COG0517	IMP dehydrogenase activity
BIND_RS08035	COG1459	type II secretion system
BIND_RS08040	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BIND_RS08045	COG1450	Type ii and iii secretion system protein
BIND_RS08050	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
BIND_RS08105	COG1126	abc transporter atp-binding protein
BIND_RS08110	COG0765	amino acid transport
BIND_RS08115	COG4597	amino acid ABC transporter
BIND_RS08120	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BIND_RS08130	COG0626	cystathionine gamma-synthase activity
BIND_RS08145	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BIND_RS08165	COG3511	phospholipase C
BIND_RS08170	COG1858	cytochrome C peroxidase
BIND_RS08185	COG4176	ABC-type proline glycine betaine transport system permease component
BIND_RS08200	COG2239	Acts as a magnesium transporter
BIND_RS08215	COG0321	lipoyl(octanoyl) transferase activity
BIND_RS08240	COG2983	Belongs to the UPF0260 family
BIND_RS08245	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BIND_RS08250	COG3811	Belongs to the UPF0386 family
BIND_RS08260	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BIND_RS08295	COG0433	COG0433 Predicted ATPase
BIND_RS08300	COG0306	phosphate transporter
BIND_RS08310	COG2205	protein histidine kinase activity
BIND_RS08320	COG2166	iron-sulfur cluster assembly
BIND_RS08325	COG4957	zinc ion binding
BIND_RS08330	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BIND_RS08345	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BIND_RS08360	COG1309	transcriptional regulator
BIND_RS08365	COG0463	Glycosyl transferase, family 2
BIND_RS08370	COG0728	peptidoglycan biosynthetic process
BIND_RS08385	COG2759	Belongs to the formate--tetrahydrofolate ligase family
BIND_RS08390	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BIND_RS08415	COG0436	Aminotransferase
BIND_RS08430	COG0531	amino acid
BIND_RS08445	COG0537	adenosine 5'-monophosphoramidase activity
BIND_RS08455	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BIND_RS08465	COG1686	Belongs to the peptidase S11 family
BIND_RS08470	COG0484	heat shock protein binding
BIND_RS08475	COG0625	glutathione transferase activity
BIND_RS08485	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BIND_RS08490	COG0424	maF-like protein
BIND_RS08495	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BIND_RS08500	COG4122	O-methyltransferase activity
BIND_RS08505	COG1183	phosphatidylcholine synthase activity
BIND_RS08510	COG0688	phosphatidylethanolamine metabolic process
BIND_RS08545	COG0484	heat shock protein binding
BIND_RS08580	COG0528	UMP kinase activity
BIND_RS08585	COG0528	UMP kinase activity
BIND_RS08590	COG2217	Heavy metal translocating P-type atpase
BIND_RS08625	COG0851	Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell
BIND_RS08630	COG2894	cell division
BIND_RS08635	COG0850	regulation of cytokinetic process
BIND_RS08640	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BIND_RS08645	COG2814	Major facilitator Superfamily
BIND_RS08660	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BIND_RS08675	COG0322	excinuclease ABC activity
BIND_RS08680	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BIND_RS08690	COG0314	molybdopterin synthase activity
BIND_RS08700	COG0729	surface antigen
BIND_RS08715	COG2186	Transcriptional regulator
BIND_RS08720	COG2390	Transcriptional regulator
BIND_RS08740	COG0525	valine-tRNA ligase activity
BIND_RS08760	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BIND_RS08780	COG0330	HflC and HflK could
BIND_RS08785	COG0330	HflC and HflK could
BIND_RS08815	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BIND_RS08820	COG0459	protein refolding
BIND_RS08825	COG0776	regulation of translation
BIND_RS08830	COG4178	(ABC) transporter
BIND_RS08840	COG0842	Transport permease protein
BIND_RS08845	COG1129	ABC transporter
BIND_RS08845	COG0842	Transport permease protein
BIND_RS08850	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIND_RS08865	COG1024	Enoyl-CoA hydratase
BIND_RS08885	COG2086	electron transfer activity
BIND_RS08895	COG1960	acyl-CoA dehydrogenase activity
BIND_RS08900	COG1250	3-hydroxyacyl-CoA dehydrogenase
BIND_RS08900	COG1024	Enoyl-CoA hydratase
BIND_RS08905	COG0183	Belongs to the thiolase family
BIND_RS08910	COG0318	PFAM AMP-dependent synthetase and ligase
BIND_RS08950	COG0667	Aldo Keto reductase
BIND_RS08955	COG3755	Protein conserved in bacteria
BIND_RS08965	COG1064	alcohol dehydrogenase
BIND_RS08985	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BIND_RS08990	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BIND_RS08995	COG0124	histidyl-tRNA synthetase
BIND_RS09005	COG0513	Belongs to the DEAD box helicase family
BIND_RS09035	COG1376	ErfK ybiS ycfS ynhG family protein
BIND_RS09035	COG1388	LysM domain
BIND_RS09045	COG2896	Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate
BIND_RS09050	COG0489	protein tyrosine kinase activity
BIND_RS09060	COG2084	Dehydrogenase
BIND_RS09070	COG1024	Enoyl-CoA hydratase
BIND_RS09090	COG3961	Belongs to the TPP enzyme family
BIND_RS09095	COG1136	(ABC) transporter
BIND_RS09105	COG0442	prolyl-tRNA aminoacylation
BIND_RS09110	COG0840	transmembrane signaling receptor activity
BIND_RS09120	COG1819	glycosyl
BIND_RS09125	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BIND_RS09130	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BIND_RS09135	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BIND_RS09150	COG2124	cytochrome p450
BIND_RS09160	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BIND_RS09160	COG0574	Belongs to the PEP-utilizing enzyme family
BIND_RS09170	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BIND_RS09185	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BIND_RS09220	COG1012	belongs to the aldehyde dehydrogenase family
BIND_RS09240	COG4221	oxidoreductase activity
BIND_RS09245	COG2226	methyltransferase
BIND_RS09245	COG0596	Alpha beta hydrolase
BIND_RS09245	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIND_RS09265	COG0300	oxidoreductase activity
BIND_RS09280	COG0583	DNA-binding transcription factor activity
BIND_RS09285	COG1902	pentaerythritol trinitrate reductase activity
BIND_RS09305	COG3511	phospholipase C
BIND_RS09350	COG2072	flavoprotein involved in K transport
BIND_RS09355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS09365	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS09370	COG0778	Nitroreductase
BIND_RS09375	COG1960	acyl-CoA dehydrogenase activity
BIND_RS09380	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS09400	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BIND_RS09400	COG4651	solute:proton antiporter activity
BIND_RS09430	COG0469	pyruvate kinase activity
BIND_RS09450	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BIND_RS09455	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BIND_RS09460	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BIND_RS09465	COG0741	lytic transglycosylase activity
BIND_RS09500	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BIND_RS09505	COG0154	amidase activity
BIND_RS09510	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BIND_RS09515	COG2095	MarC family integral membrane protein
BIND_RS09530	COG2197	response regulator
BIND_RS09535	COG2205	protein histidine kinase activity
BIND_RS09540	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BIND_RS09560	COG2814	Major facilitator Superfamily
BIND_RS09565	COG1981	membrane
BIND_RS09580	COG0702	epimerase
BIND_RS09585	COG0318	PFAM AMP-dependent synthetase and ligase
BIND_RS09595	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BIND_RS09605	COG2267	carboxylic ester hydrolase activity
BIND_RS09610	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BIND_RS09615	COG0277	FAD linked oxidase domain protein
BIND_RS09620	COG0277	FAD linked oxidase domain protein
BIND_RS09625	COG0247	lactate metabolic process
BIND_RS09645	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BIND_RS09650	COG0633	Ferredoxin
BIND_RS09665	COG0590	tRNA wobble adenosine to inosine editing
BIND_RS09670	COG5265	(ABC) transporter
BIND_RS09690	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BIND_RS09695	COG0454	-acetyltransferase
BIND_RS09700	COG0215	cysteine-tRNA ligase activity
BIND_RS09710	COG3613	nucleoside 2-deoxyribosyltransferase
BIND_RS09725	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BIND_RS09725	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BIND_RS09740	COG0477	Major facilitator Superfamily
BIND_RS09745	COG0589	response to stress
BIND_RS09750	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BIND_RS09760	COG1573	uracil-dna glycosylase
BIND_RS09765	COG2205	protein histidine kinase activity
BIND_RS09780	COG0655	NAD(P)H dehydrogenase (quinone) activity
BIND_RS09790	COG3038	cytochrome b561
BIND_RS09805	COG1741	Belongs to the pirin family
BIND_RS09810	COG4689	acetoacetate decarboxylase
BIND_RS09820	COG0450	alkyl hydroperoxide reductase
BIND_RS09825	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BIND_RS09825	COG3453	Protein conserved in bacteria
BIND_RS09830	COG0640	Transcriptional regulator
BIND_RS09835	COG0730	response to heat
BIND_RS09840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BIND_RS09850	COG3119	arylsulfatase activity
BIND_RS09860	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BIND_RS09870	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BIND_RS09890	COG1346	cytolysis
BIND_RS09895	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BIND_RS09925	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BIND_RS09950	COG1763	Mo-molybdopterin cofactor biosynthetic process
BIND_RS09965	COG0243	molybdopterin cofactor binding
BIND_RS09970	COG2146	nitrite reductase [NAD(P)H] activity
BIND_RS09970	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BIND_RS09975	COG2223	nitrite transmembrane transporter activity
BIND_RS09980	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BIND_RS09980	COG1017	nitric oxide dioxygenase activity
BIND_RS09985	COG1959	2 iron, 2 sulfur cluster binding
BIND_RS09990	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BIND_RS09990	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
BIND_RS10000	COG1877	trehalose-phosphatase activity
BIND_RS10015	COG0752	glycyl-tRNA synthetase alpha subunit
BIND_RS10050	COG0285	dihydrofolate synthase activity
BIND_RS10055	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BIND_RS10060	COG0159	tryptophan synthase activity
BIND_RS10070	COG0133	tryptophan synthase activity
BIND_RS10090	COG1764	response to oxidative stress
BIND_RS10140	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BIND_RS10145	COG1120	ATPase activity
BIND_RS10150	COG2223	nitrite transmembrane transporter activity
BIND_RS10160	COG2814	Major facilitator Superfamily
BIND_RS10165	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BIND_RS10180	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BIND_RS10190	COG0277	FAD linked oxidase domain protein
BIND_RS10195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BIND_RS10200	COG1942	4-Oxalocrotonate Tautomerase
BIND_RS10210	COG1621	beta-fructofuranosidase activity
BIND_RS10225	COG0009	L-threonylcarbamoyladenylate synthase
BIND_RS10230	COG1538	Outer membrane efflux protein
BIND_RS10235	COG2814	Major facilitator Superfamily
BIND_RS10240	COG1566	PFAM secretion protein HlyD family protein
BIND_RS10250	COG1573	uracil-dna glycosylase
BIND_RS10255	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BIND_RS10275	COG2205	protein histidine kinase activity
BIND_RS10275	COG2202	Pas domain
BIND_RS10285	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BIND_RS10290	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BIND_RS10295	COG0202	RNA polymerase activity
BIND_RS10300	COG0203	ribosomal protein L17
BIND_RS10305	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BIND_RS10310	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BIND_RS10325	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BIND_RS10355	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS10375	COG1522	sequence-specific DNA binding
BIND_RS10385	COG1116	anion transmembrane transporter activity
BIND_RS10415	COG0280	phosphate acetyltransferase
BIND_RS10415	COG0281	malic enzyme
BIND_RS10435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BIND_RS10455	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BIND_RS10455	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BIND_RS10470	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BIND_RS10500	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BIND_RS10505	COG2271	Major facilitator Superfamily
BIND_RS10510	COG0235	Class ii aldolase
BIND_RS10515	COG1609	Transcriptional regulator
BIND_RS10525	COG2271	Major facilitator Superfamily
BIND_RS10530	COG2084	Dehydrogenase
BIND_RS10535	COG3622	Belongs to the hyi family
BIND_RS10540	COG3395	kinase activity
BIND_RS10545	COG0596	Alpha beta hydrolase
BIND_RS10555	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS10570	COG4206	TonB-dependent receptor
BIND_RS10630	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BIND_RS10650	COG0335	large ribosomal subunit rRNA binding
BIND_RS10660	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BIND_RS10680	COG1136	(ABC) transporter
BIND_RS10680	COG0577	efflux transmembrane transporter activity
BIND_RS10690	COG1309	transcriptional regulator
BIND_RS10695	COG1741	Belongs to the pirin family
BIND_RS10705	COG2169	Transcriptional regulator
BIND_RS10705	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BIND_RS10710	COG2814	Major facilitator Superfamily
BIND_RS10740	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BIND_RS10740	COG2755	lipolytic protein G-D-S-L family
BIND_RS10750	COG0751	glycine-tRNA ligase activity
BIND_RS10755	COG0477	Major facilitator Superfamily
BIND_RS10815	COG0798	PFAM Bile acid sodium symporter
BIND_RS10835	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BIND_RS10910	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BIND_RS10915	COG1324	tolerance protein
BIND_RS10920	COG0006	proline dipeptidase activity
BIND_RS10940	COG2022	thiamine diphosphate biosynthetic process
BIND_RS10990	COG2887	Belongs to the helicase family. UvrD subfamily
BIND_RS10995	COG1074	ATP-dependent DNA helicase activity
BIND_RS11005	COG0602	queuosine metabolic process
BIND_RS11010	COG0720	synthase
BIND_RS11015	COG1309	transcriptional regulator
BIND_RS11020	COG1335	isochorismatase
BIND_RS11025	COG3180	Ammonia monooxygenase
BIND_RS11035	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BIND_RS11040	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BIND_RS11045	COG0740	serine-type endopeptidase activity
BIND_RS11055	COG0544	peptidyl-prolyl cis-trans isomerase activity
BIND_RS11065	COG2132	Multicopper oxidase
BIND_RS11090	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BIND_RS11090	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BIND_RS11105	COG4166	transmembrane transport
BIND_RS11120	COG0346	lactoylglutathione lyase activity
BIND_RS11135	COG3243	poly(R)-hydroxyalkanoic acid synthase
BIND_RS11145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BIND_RS11150	COG3957	D-xylulose 5-phosphate D-fructose 6-phosphate phosphoketolase
BIND_RS11155	COG2183	response to ionizing radiation
BIND_RS11175	COG1802	Transcriptional regulator
BIND_RS11185	COG2271	Major facilitator Superfamily
BIND_RS11190	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BIND_RS11195	COG1024	Enoyl-CoA hydratase
BIND_RS11215	COG1063	alcohol dehydrogenase
BIND_RS11220	COG3284	Transcriptional regulator
BIND_RS11240	COG0785	Cytochrome C biogenesis protein
BIND_RS11245	COG0052	Belongs to the universal ribosomal protein uS2 family
BIND_RS11250	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BIND_RS11275	COG4235	cytochrome complex assembly
BIND_RS11280	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BIND_RS11285	COG1138	Cytochrome C-type biogenesis protein
BIND_RS11290	COG3088	subunit of a heme lyase
BIND_RS11295	COG1253	flavin adenine dinucleotide binding
BIND_RS11300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BIND_RS11305	COG0745	RESPONSE REGULATOR receiver
BIND_RS11310	COG2205	protein histidine kinase activity
BIND_RS11315	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BIND_RS11330	COG1301	dicarboxylic acid transport
BIND_RS11335	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BIND_RS11340	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BIND_RS11360	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BIND_RS11390	COG0534	Mate efflux family protein
BIND_RS11395	COG0586	Pfam SNARE associated Golgi protein
BIND_RS11405	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BIND_RS11410	COG4208	sulfate ABC transporter
BIND_RS11415	COG0555	PFAM binding-protein-dependent transport systems inner membrane component
BIND_RS11425	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BIND_RS11430	COG0175	sulfate reduction
BIND_RS11440	COG2321	neutral zinc metallopeptidase
BIND_RS11525	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BIND_RS11530	COG4149	molybdate abc transporter
BIND_RS11535	COG0725	ABC transporter, periplasmic molybdate-binding protein
BIND_RS11550	COG3685	Protein conserved in bacteria
BIND_RS11555	COG3237	CsbD-like
BIND_RS11560	COG1472	Belongs to the glycosyl hydrolase 3 family
BIND_RS11595	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BIND_RS11600	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BIND_RS11610	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BIND_RS11620	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BIND_RS11630	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BIND_RS11640	COG2814	Major facilitator Superfamily
BIND_RS11645	COG0360	Binds together with S18 to 16S ribosomal RNA
BIND_RS11650	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BIND_RS11660	COG0359	binds to the 23S rRNA
BIND_RS11665	COG0305	Participates in initiation and elongation during chromosome replication
BIND_RS11670	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BIND_RS11685	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BIND_RS11690	COG4221	oxidoreductase activity
BIND_RS11715	COG1160	GTP binding
BIND_RS11755	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BIND_RS11770	COG1120	ATPase activity
BIND_RS11775	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BIND_RS11780	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
BIND_RS11795	COG0328	RNA-DNA hybrid ribonuclease activity
BIND_RS11800	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BIND_RS11805	COG0343	queuine tRNA-ribosyltransferase activity
BIND_RS11810	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BIND_RS11820	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS11830	COG1879	ABC-type sugar transport system periplasmic component
BIND_RS11835	COG1063	alcohol dehydrogenase
BIND_RS11850	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BIND_RS11855	COG0492	ferredoxin-NADP+ reductase activity
BIND_RS11860	COG0633	Ferredoxin
BIND_RS11905	COG0625	glutathione transferase activity
BIND_RS11940	COG1247	-acetyltransferase
BIND_RS11960	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BIND_RS11990	COG2814	Major facilitator Superfamily
BIND_RS11995	COG1187	pseudouridine synthase activity
BIND_RS12005	COG0742	ribosomal rna small subunit methyltransferase
BIND_RS12015	COG4771	TonB-dependent receptor
BIND_RS12025	COG1999	signal sequence binding
BIND_RS12035	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BIND_RS12035	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BIND_RS12040	COG1007	ATP synthesis coupled electron transport
BIND_RS12055	COG0713	ATP synthesis coupled electron transport
BIND_RS12065	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BIND_RS12070	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BIND_RS12085	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BIND_RS12095	COG0649	NAD binding
BIND_RS12100	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BIND_RS12105	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BIND_RS12155	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BIND_RS12160	COG5487	UPF0391 membrane protein
BIND_RS12180	COG3106	COG3106 Predicted ATPase
BIND_RS12185	COG3768	UPF0283 membrane protein
BIND_RS12210	COG0598	Magnesium transport protein CorA
BIND_RS12225	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BIND_RS12230	COG0440	acetolactate synthase activity
BIND_RS12235	COG0028	Belongs to the TPP enzyme family
BIND_RS12260	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BIND_RS12265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BIND_RS12270	COG1321	iron dependent repressor
BIND_RS12275	COG1914	H( )-stimulated, divalent metal cation uptake system
BIND_RS12280	COG0488	(ABC) transporter
BIND_RS12290	COG0450	alkyl hydroperoxide reductase
BIND_RS12295	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BIND_RS12305	COG0105	UTP biosynthetic process
BIND_RS12310	COG0483	inositol monophosphate 1-phosphatase activity
BIND_RS12315	COG2271	Major facilitator Superfamily
BIND_RS12320	COG1116	anion transmembrane transporter activity
BIND_RS12325	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BIND_RS12330	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BIND_RS12340	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BIND_RS12345	COG0571	ribonuclease III activity
BIND_RS12355	COG0736	holo-[acyl-carrier-protein] synthase activity
BIND_RS12360	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BIND_RS12370	COG1758	RNA polymerase activity
BIND_RS12380	COG1573	uracil-dna glycosylase
BIND_RS12410	COG0501	Belongs to the peptidase M48B family
BIND_RS12415	COG1464	Belongs to the NlpA lipoprotein family
BIND_RS12420	COG2011	ABC-type metal ion transport system permease component
BIND_RS12425	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BIND_RS12450	COG1175	transmembrane transport
BIND_RS12460	COG1070	Carbohydrate kinase
BIND_RS12490	COG0583	DNA-binding transcription factor activity
BIND_RS12505	COG0651	ATP synthesis coupled electron transport
BIND_RS12510	COG0650	Formate hydrogenlyase subunit 4
BIND_RS12520	COG0651	ATP synthesis coupled electron transport
BIND_RS12525	COG0649	NAD binding
BIND_RS12530	COG3260	NADH ubiquinone oxidoreductase 20
BIND_RS12545	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BIND_RS12550	COG4573	that is required for full activity and stability of the Y subunit. Could have a chaperone-like function for the proper and stable folding of
BIND_RS12555	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BIND_RS12565	COG2814	Major facilitator Superfamily
BIND_RS12610	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BIND_RS12615	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BIND_RS12620	COG3750	Belongs to the UPF0335 family
BIND_RS12630	COG0583	DNA-binding transcription factor activity
BIND_RS12715	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BIND_RS12725	COG3842	ATPase activity
BIND_RS12735	COG1840	ABC-type Fe3 transport system, periplasmic component
BIND_RS12745	COG2059	Chromate
BIND_RS12780	COG0531	amino acid
BIND_RS12795	COG2030	dehydratase
BIND_RS12800	COG2301	Belongs to the HpcH HpaI aldolase family
BIND_RS12805	COG0477	Major facilitator Superfamily
BIND_RS12830	COG0583	DNA-binding transcription factor activity
BIND_RS12835	COG2055	Belongs to the LDH2 MDH2 oxidoreductase family
BIND_RS12855	COG0538	isocitrate dehydrogenase activity
BIND_RS12860	COG4166	transmembrane transport
BIND_RS12875	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BIND_RS12895	COG4608	Belongs to the ABC transporter superfamily
BIND_RS12910	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS12930	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BIND_RS12965	COG0167	dihydroorotate dehydrogenase activity
BIND_RS12970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS12975	COG0667	Aldo Keto reductase
BIND_RS13010	COG2814	Major facilitator Superfamily
BIND_RS13010	COG0477	Major facilitator Superfamily
BIND_RS13060	COG0318	PFAM AMP-dependent synthetase and ligase
BIND_RS13095	COG2801	Transposase and inactivated derivatives
BIND_RS13120	COG2226	methyltransferase
BIND_RS13140	COG5322	oxidoreductase activity
BIND_RS13140	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BIND_RS13150	COG0644	oxidoreductase
BIND_RS13185	COG2207	Transcriptional regulator
BIND_RS13190	COG0667	Aldo Keto reductase
BIND_RS13205	COG2936	dipeptidyl-peptidase activity
BIND_RS13255	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS13260	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BIND_RS13270	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BIND_RS13295	COG1064	alcohol dehydrogenase
BIND_RS13325	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BIND_RS13330	COG2005	Transcriptional regulator
BIND_RS13330	COG3585	molybdate ion transport
BIND_RS13340	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BIND_RS13340	COG0662	Cupin 2, conserved barrel domain protein
BIND_RS13355	COG3206	protein involved in exopolysaccharide biosynthesis
BIND_RS13355	COG0489	protein tyrosine kinase activity
BIND_RS13440	COG0582	viral genome integration into host DNA
BIND_RS13475	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BIND_RS13490	COG0464	growth
BIND_RS13525	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BIND_RS13530	COG3191	aminopeptidase activity
BIND_RS13550	COG1360	Flagellar Motor Protein
BIND_RS13565	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BIND_RS13590	COG4689	acetoacetate decarboxylase
BIND_RS13595	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS13600	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BIND_RS13610	COG1388	LysM domain
BIND_RS13610	COG4942	peptidase
BIND_RS13615	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BIND_RS13620	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BIND_RS13625	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BIND_RS13630	COG0805	protein transport
BIND_RS13640	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BIND_RS13650	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BIND_RS13655	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BIND_RS13665	COG0018	arginyl-trna synthetase
BIND_RS13675	COG0316	Belongs to the HesB IscA family
BIND_RS13700	COG0129	dihydroxy-acid dehydratase activity
BIND_RS13715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BIND_RS13775	COG2835	tetraacyldisaccharide 4'-kinase activity
BIND_RS13780	COG1946	Acyl-CoA thioesterase
BIND_RS13790	COG0347	Belongs to the P(II) protein family
BIND_RS13795	COG0004	ammonium transporteR
BIND_RS13800	COG0166	Belongs to the GPI family
BIND_RS13810	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BIND_RS13815	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BIND_RS13815	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BIND_RS13825	COG0642	Histidine kinase
BIND_RS13830	COG0745	RESPONSE REGULATOR receiver
BIND_RS13845	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BIND_RS13845	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BIND_RS13870	COG1053	succinate dehydrogenase
BIND_RS13935	COG3206	protein involved in exopolysaccharide biosynthesis
BIND_RS13935	COG0489	protein tyrosine kinase activity
BIND_RS13950	COG0673	inositol 2-dehydrogenase activity
BIND_RS13970	COG0667	Aldo Keto reductase
BIND_RS13985	COG1082	Xylose isomerase domain protein TIM barrel
BIND_RS13990	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BIND_RS13995	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BIND_RS14005	COG0356	it plays a direct role in the translocation of protons across the membrane
BIND_RS14015	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BIND_RS14015	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BIND_RS14025	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BIND_RS14040	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS14045	COG0583	DNA-binding transcription factor activity
BIND_RS14055	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BIND_RS14060	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BIND_RS14085	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BIND_RS14130	COG0587	DNA-directed DNA polymerase activity
BIND_RS14140	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BIND_RS14150	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BIND_RS14155	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BIND_RS14160	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BIND_RS14170	COG4786	Flagellar basal body rod
BIND_RS14175	COG1157	protein secretion by the type III secretion system
BIND_RS14190	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BIND_RS14195	COG1522	sequence-specific DNA binding
BIND_RS14205	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS14210	COG0583	DNA-binding transcription factor activity
BIND_RS14230	COG1172	Belongs to the binding-protein-dependent transport system permease family
BIND_RS14235	COG1129	ABC transporter
BIND_RS14245	COG0673	inositol 2-dehydrogenase activity
BIND_RS14260	COG0673	inositol 2-dehydrogenase activity
BIND_RS14290	COG3962	Belongs to the TPP enzyme family
BIND_RS14300	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS14305	COG1879	ABC-type sugar transport system periplasmic component
BIND_RS14340	COG0714	Associated with various cellular activities
BIND_RS14350	COG0617	tRNA 3'-terminal CCA addition
BIND_RS14370	COG2755	lipolytic protein G-D-S-L family
BIND_RS14370	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BIND_RS14385	COG1012	belongs to the aldehyde dehydrogenase family
BIND_RS14390	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BIND_RS14405	COG1404	Belongs to the peptidase S8 family
BIND_RS14415	COG0469	pyruvate kinase activity
BIND_RS14420	COG1012	belongs to the aldehyde dehydrogenase family
BIND_RS14430	COG1879	ABC-type sugar transport system periplasmic component
BIND_RS14435	COG1172	Belongs to the binding-protein-dependent transport system permease family
BIND_RS14460	COG0364	Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone
BIND_RS14465	COG0129	dihydroxy-acid dehydratase activity
BIND_RS14470	COG0800	Aldolase
BIND_RS14480	COG0800	Aldolase
BIND_RS14485	COG3734	2-keto-3-deoxy-galactonokinase
BIND_RS14490	COG1414	Transcriptional regulator
BIND_RS14500	COG0129	dihydroxy-acid dehydratase activity
BIND_RS14505	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BIND_RS14590	COG1309	transcriptional regulator
BIND_RS14600	COG0519	Catalyzes the synthesis of GMP from XMP
BIND_RS14600	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BIND_RS14610	COG0024	Methionine aminopeptidase
BIND_RS14615	COG2003	Belongs to the UPF0758 family
BIND_RS14620	COG5001	Diguanylate cyclase
BIND_RS14625	COG5425	PFAM Usg family protein
BIND_RS14630	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BIND_RS14635	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BIND_RS14635	COG3608	succinylglutamate desuccinylase aspartoacylase
BIND_RS14645	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BIND_RS14655	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS14660	COG2226	methyltransferase
BIND_RS14665	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BIND_RS14675	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BIND_RS14680	COG0756	dUTP diphosphatase activity
BIND_RS14685	COG1959	2 iron, 2 sulfur cluster binding
BIND_RS14700	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BIND_RS14705	COG0837	glucose binding
BIND_RS14710	COG1838	Catalyzes the reversible hydration of fumarate to (S)- malate
BIND_RS14710	COG1951	Catalyzes the reversible hydration of fumarate to (S)- malate
BIND_RS14720	COG0825	malonyl-CoA metabolic process
BIND_RS14735	COG1538	Outer membrane efflux protein
BIND_RS14740	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BIND_RS14745	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BIND_RS14760	COG0135	phosphoribosylanthranilate isomerase activity
BIND_RS14770	COG0776	regulation of translation
BIND_RS14775	COG0616	signal peptide processing
BIND_RS14780	COG0494	nUDIX hydrolase
BIND_RS14785	COG0793	Belongs to the peptidase S41A family
BIND_RS14795	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BIND_RS14800	COG0799	negative regulation of ribosome biogenesis
BIND_RS14805	COG0443	Heat shock 70 kDa protein
BIND_RS14810	COG0539	negative regulation of cytoplasmic translation
BIND_RS14825	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BIND_RS14860	COG2378	regulation of single-species biofilm formation
BIND_RS14870	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BIND_RS14890	COG1335	isochorismatase
BIND_RS14915	COG4977	sequence-specific DNA binding
BIND_RS14920	COG3967	Belongs to the short-chain dehydrogenases reductases (SDR) family
BIND_RS14925	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BIND_RS14945	COG0667	Aldo Keto reductase
BIND_RS14950	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BIND_RS14965	COG0583	DNA-binding transcription factor activity
BIND_RS15035	COG0583	DNA-binding transcription factor activity
BIND_RS15065	COG3685	Protein conserved in bacteria
BIND_RS15080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BIND_RS15095	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS15105	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS15125	COG0628	permease
BIND_RS15140	COG2204	response regulator
BIND_RS15230	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS15235	COG0735	belongs to the Fur family
BIND_RS15240	COG0456	acetyltransferase
BIND_RS15245	COG0156	8-amino-7-oxononanoate synthase activity
BIND_RS15255	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BIND_RS15260	COG0366	Alpha amylase catalytic
BIND_RS15275	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BIND_RS15315	COG0477	Major facilitator Superfamily
BIND_RS15320	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BIND_RS15325	COG1381	Involved in DNA repair and RecF pathway recombination
BIND_RS15350	COG0070	glutamate synthase
BIND_RS15350	COG0067	glutamate synthase
BIND_RS15350	COG0069	glutamate synthase activity
BIND_RS15360	COG1216	Glycosyl transferase, family 2
BIND_RS15370	COG1278	Cold shock
BIND_RS15380	COG0482	sulfurtransferase activity
BIND_RS15395	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BIND_RS15405	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BIND_RS15410	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BIND_RS15425	COG3265	gluconokinase activity
BIND_RS15430	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BIND_RS15440	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BIND_RS15460	COG2308	Evidence 4 Homologs of previously reported genes of
BIND_RS15470	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
BIND_RS15480	COG1376	ErfK ybiS ycfS ynhG family protein
BIND_RS15490	COG0183	Belongs to the thiolase family
BIND_RS15505	COG0811	peptide transport
BIND_RS15510	COG0848	biopolymer transport protein
BIND_RS15535	COG1450	Type ii and iii secretion system protein
BIND_RS15555	COG1879	ABC-type sugar transport system periplasmic component
BIND_RS15560	COG4214	carbohydrate transport
BIND_RS15565	COG1129	ABC transporter
BIND_RS15570	COG4213	ABC transporter substrate-binding protein
BIND_RS15575	COG3386	PFAM SMP-30 Gluconolaconase
BIND_RS15580	COG2017	converts alpha-aldose to the beta-anomer
BIND_RS15625	COG1053	succinate dehydrogenase
BIND_RS15635	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BIND_RS15640	COG4771	TonB-dependent receptor
BIND_RS15670	COG2951	lytic endotransglycosylase activity
BIND_RS15675	COG0574	Belongs to the PEP-utilizing enzyme family
BIND_RS15675	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BIND_RS15685	COG3284	Transcriptional regulator
BIND_RS15690	COG1278	Cold shock
BIND_RS15710	COG1250	3-hydroxyacyl-CoA dehydrogenase
BIND_RS15725	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BIND_RS15740	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BIND_RS15745	COG3030	protein affecting phage T7 exclusion by the F plasmid
BIND_RS15755	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BIND_RS15780	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BIND_RS15785	COG0271	Belongs to the BolA IbaG family
BIND_RS15790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BIND_RS15795	COG0047	phosphoribosylformylglycinamidine synthase activity
BIND_RS15805	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BIND_RS15815	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BIND_RS15820	COG0481	GTPase activity
BIND_RS15825	COG0189	ligase activity
BIND_RS15830	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BIND_RS15845	COG3220	belongs to the UPF0276 family
BIND_RS15875	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BIND_RS15885	COG3830	Belongs to the UPF0237 family
BIND_RS15885	COG0560	Phosphoserine phosphatase
BIND_RS15900	COG1984	allophanate hydrolase subunit 2
BIND_RS15920	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BIND_RS15945	COG1132	(ABC) transporter
BIND_RS15955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BIND_RS15960	COG1562	ergosterol biosynthetic process
BIND_RS15965	COG1562	ergosterol biosynthetic process
BIND_RS15970	COG1232	Catalyzes the 6-electron oxidation of protoporphyrinogen-IX to form protoporphyrin-IX
BIND_RS15975	COG1657	PFAM Prenyltransferase squalene oxidase
BIND_RS15995	COG4783	chaperone-mediated protein folding
BIND_RS16175	COG1185	polyribonucleotide nucleotidyltransferase activity
BIND_RS16180	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BIND_RS16190	COG2326	polyphosphate kinase activity
BIND_RS16195	COG5002	protein histidine kinase activity
BIND_RS16200	COG0237	dephospho-CoA kinase activity
BIND_RS16215	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BIND_RS16260	COG1970	mechanosensitive ion channel activity
BIND_RS16265	COG0436	Aminotransferase
BIND_RS16270	COG0156	8-amino-7-oxononanoate synthase activity
BIND_RS16310	COG0483	inositol monophosphate 1-phosphatase activity
BIND_RS16315	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BIND_RS16325	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BIND_RS16340	COG3264	Mechanosensitive ion channel
BIND_RS16340	COG1196	nuclear chromosome segregation
BIND_RS16350	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BIND_RS16355	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BIND_RS16365	COG3750	Belongs to the UPF0335 family
BIND_RS16375	COG5507	3-demethylubiquinone-9 3-methyltransferase
BIND_RS16400	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BIND_RS16405	COG2205	protein histidine kinase activity
BIND_RS16405	COG0784	Response regulator, receiver
BIND_RS16405	COG5002	protein histidine kinase activity
BIND_RS16445	COG0114	fumarate hydratase activity
BIND_RS16450	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BIND_RS16460	COG4221	oxidoreductase activity
BIND_RS16475	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BIND_RS16475	COG0072	phenylalanine-tRNA ligase activity
BIND_RS16490	COG1295	ribonuclease BN
BIND_RS16515	COG0653	protein targeting
BIND_RS16530	COG3189	MarR family transcriptional regulator
BIND_RS16535	COG0339	signal peptide processing
BIND_RS16540	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BIND_RS16545	COG0830	nickel cation binding
BIND_RS16550	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BIND_RS16570	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BIND_RS16580	COG0583	DNA-binding transcription factor activity
BIND_RS16590	COG1250	3-hydroxyacyl-CoA dehydrogenase
BIND_RS16590	COG1024	Enoyl-CoA hydratase
BIND_RS16595	COG1960	acyl-CoA dehydrogenase activity
BIND_RS16600	COG2086	electron transfer activity
BIND_RS16610	COG1788	Acyl CoA acetate 3-ketoacid CoA transferase, alpha subunit
BIND_RS16615	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BIND_RS16620	COG1024	Enoyl-CoA hydratase
BIND_RS16650	COG2307	Protein conserved in bacteria
BIND_RS16650	COG2308	Evidence 4 Homologs of previously reported genes of
BIND_RS16655	COG0521	Mo-molybdopterin cofactor biosynthetic process
BIND_RS16685	COG1294	oxidase, subunit
BIND_RS16690	COG1271	oxidase subunit
BIND_RS16705	COG0837	glucose binding
BIND_RS16710	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BIND_RS16720	COG1610	YqeY-like protein
BIND_RS16725	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BIND_RS16735	COG0358	DNA primase activity
BIND_RS16740	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BIND_RS16755	COG5002	protein histidine kinase activity
BIND_RS16760	COG0745	RESPONSE REGULATOR receiver
BIND_RS16785	COG0832	Belongs to the urease beta subunit family
BIND_RS16785	COG0831	urea catabolic process
BIND_RS16790	COG0829	nickel cation binding
BIND_RS16820	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BIND_RS16840	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BIND_RS16845	COG0535	radical SAM domain protein
BIND_RS16855	COG5424	Ring cyclization and eight-electron oxidation of 3a-(2- amino-2-carboxyethyl)-4,5-dioxo-4,5,6,7,8,9-hexahydroquinoline- 7,9-dicarboxylic-acid to PQQ
BIND_RS16860	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BIND_RS16875	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BIND_RS16880	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BIND_RS16885	COG0594	ribonuclease P activity
BIND_RS16890	COG0706	membrane insertase activity
BIND_RS16900	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BIND_RS16910	COG2171	N-acyltransferase activity
BIND_RS16925	COG1573	uracil-dna glycosylase
BIND_RS16930	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BIND_RS16945	COG0450	alkyl hydroperoxide reductase
BIND_RS16950	COG0667	Aldo Keto reductase
BIND_RS16990	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BIND_RS17005	COG0228	four-way junction DNA binding
BIND_RS17010	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BIND_RS17015	COG0336	Belongs to the RNA methyltransferase TrmD family
BIND_RS17030	COG3474	cytochrome
BIND_RS17035	COG4166	transmembrane transport
BIND_RS17040	COG4174	ABC transporter (Permease)
BIND_RS17045	COG4239	(ABC) transporter, permease
BIND_RS17050	COG4172	Belongs to the ABC transporter superfamily
BIND_RS17085	COG2010	Cytochrome c
BIND_RS17085	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BIND_RS17140	COG0776	regulation of translation
BIND_RS17145	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BIND_RS17150	COG0416	fatty acid biosynthetic process
BIND_RS17180	COG3387	PFAM Glycoside hydrolase 15-related
BIND_RS17200	COG3961	Belongs to the TPP enzyme family
BIND_RS17205	COG0477	Major facilitator Superfamily
BIND_RS17220	COG0459	protein refolding
BIND_RS17235	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
BIND_RS17245	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BIND_RS17255	COG2885	chlorophyll binding
BIND_RS17265	COG3781	membrane
BIND_RS17275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BIND_RS17280	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BIND_RS17290	COG4974	Belongs to the 'phage' integrase family
BIND_RS17295	COG0226	Part of the ABC transporter complex PstSACB involved in phosphate import
BIND_RS17300	COG0573	inorganic phosphate transmembrane transporter activity
BIND_RS17305	COG0581	inorganic phosphate transmembrane transporter activity
BIND_RS17310	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BIND_RS17315	COG0704	Plays a role in the regulation of phosphate uptake
BIND_RS17320	COG0745	RESPONSE REGULATOR receiver
BIND_RS17330	COG4948	Mandelate Racemase Muconate Lactonizing
BIND_RS17335	COG0557	exoribonuclease II activity
BIND_RS17340	COG1754	DNA topoisomerase type I activity
BIND_RS17340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BIND_RS17345	COG0540	Belongs to the ATCase OTCase family
BIND_RS17350	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BIND_RS17355	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BIND_RS17360	COG0758	DNA mediated transformation
BIND_RS17380	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BIND_RS17440	COG0318	PFAM AMP-dependent synthetase and ligase
BIND_RS17450	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BIND_RS17460	COG1414	Transcriptional regulator
BIND_RS17480	COG0494	nUDIX hydrolase
BIND_RS17490	COG5002	protein histidine kinase activity
BIND_RS17495	COG0745	RESPONSE REGULATOR receiver
BIND_RS17515	COG0277	FAD linked oxidase domain protein
BIND_RS17535	COG0583	DNA-binding transcription factor activity
BIND_RS17540	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BIND_RS17545	COG0066	3-isopropylmalate dehydratase activity
BIND_RS17550	COG0596	Alpha beta hydrolase
BIND_RS17555	COG1301	dicarboxylic acid transport
BIND_RS17595	COG4166	transmembrane transport
BIND_RS17605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BIND_RS17610	COG4172	Belongs to the ABC transporter superfamily
BIND_RS17615	COG3588	fructose-bisphosphate aldolase
BIND_RS17620	COG0126	phosphoglycerate kinase activity
BIND_RS17640	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BIND_RS17645	COG1692	metallophosphoesterase
BIND_RS17665	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BIND_RS17675	COG0737	Belongs to the 5'-nucleotidase family
BIND_RS17710	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BIND_RS17725	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BIND_RS17730	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BIND_RS17735	COG2814	Major facilitator Superfamily
BIND_RS17740	COG0514	ATP-dependent DNA helicase (RecQ)
BIND_RS17755	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BIND_RS17770	COG0792	nuclease activity
BIND_RS17775	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BIND_RS17780	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BIND_RS17780	COG3218	ABC-type transport auxiliary lipoprotein component
BIND_RS17785	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BIND_RS17790	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BIND_RS17795	COG1091	dTDP-4-dehydrorhamnose reductase activity
BIND_RS17800	COG1088	dTDP-glucose 4,6-dehydratase activity
BIND_RS17805	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BIND_RS17815	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BIND_RS17850	COG2099	Precorrin-6x reductase
BIND_RS17875	COG1903	Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A
BIND_RS17880	COG1797	cobyrinic acid a,c-diamide synthase activity
BIND_RS17885	COG0564	pseudouridine synthase activity
BIND_RS17900	COG0352	thiamine-phosphate diphosphorylase activity
BIND_RS17905	COG1802	Transcriptional regulator
BIND_RS17910	COG0075	2-aminoethylphosphonate-pyruvate transaminase activity
BIND_RS17915	COG2271	Major facilitator Superfamily
BIND_RS17945	COG5000	phosphorelay sensor kinase activity
BIND_RS17955	COG0505	Belongs to the CarA family
BIND_RS17975	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BIND_RS18020	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BIND_RS18030	COG0745	RESPONSE REGULATOR receiver
BIND_RS18035	COG2205	protein histidine kinase activity
BIND_RS18060	COG1843	Required for flagellar hook formation. May act as a scaffolding protein
BIND_RS18065	COG5443	negative regulation of bacterial-type flagellum assembly
BIND_RS18080	COG1256	bacterial-type flagellum assembly
BIND_RS18080	COG4786	Flagellar basal body rod
BIND_RS18135	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BIND_RS18140	COG1981	membrane
BIND_RS18145	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BIND_RS18150	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BIND_RS18155	COG0424	maF-like protein
BIND_RS18160	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BIND_RS18170	COG3411	Ferredoxin
BIND_RS18180	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BIND_RS18190	COG2154	pterin-4-alpha-carbinolamine dehydratase
BIND_RS18195	COG1872	DUF167
BIND_RS18200	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BIND_RS18205	COG0193	aminoacyl-tRNA hydrolase activity
BIND_RS18210	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BIND_RS18215	COG2084	Dehydrogenase
BIND_RS18240	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BIND_RS18245	COG1684	flagellar biosynthetic protein fliR
BIND_RS18255	COG1028	Short-chain dehydrogenase reductase Sdr
BIND_RS18275	COG0730	response to heat
BIND_RS18280	COG0488	(ABC) transporter
BIND_RS18290	COG3800	Transcriptional regulator
BIND_RS18290	COG1396	sequence-specific DNA binding
BIND_RS18315	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BIND_RS18330	COG0039	L-malate dehydrogenase activity
BIND_RS18335	COG0045	succinate-CoA ligase (ADP-forming) activity
BIND_RS18340	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BIND_RS18350	COG0508	dehydrogenase complex catalyzes the overall conversion of
BIND_RS18355	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BIND_RS18380	COG2137	regulation of response to DNA damage stimulus
BIND_RS18390	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BIND_RS18405	COG0628	permease
BIND_RS18410	COG0840	transmembrane signaling receptor activity
BIND_RS18420	COG0745	RESPONSE REGULATOR receiver
BIND_RS18425	COG2198	Histidine kinase
BIND_RS18425	COG0643	Histidine kinase
BIND_RS18430	COG0835	chemotaxis
BIND_RS18435	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BIND_RS18440	COG2201	protein-glutamate methylesterase activity
BIND_RS18445	COG0745	RESPONSE REGULATOR receiver
BIND_RS18450	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BIND_RS18470	COG0405	Gamma-glutamyltransferase
BIND_RS18480	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BIND_RS18490	COG0037	tRNA processing
BIND_RS18495	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BIND_RS18520	COG0483	inositol monophosphate 1-phosphatase activity
BIND_RS18535	COG2951	lytic endotransglycosylase activity
BIND_RS18540	COG2031	fatty acid transporter
BIND_RS18545	COG1338	Plays a role in the flagellum-specific transport system
BIND_RS18555	COG2063	Assembles around the rod to form the L-ring and probably protects the motor basal body from shearing forces during rotation
BIND_RS18565	COG1706	bacterial-type flagellum-dependent cell motility
BIND_RS18570	COG1261	Involved in the assembly process of the P-ring formation. It may associate with FlgF on the rod constituting a structure essential for the P-ring assembly or may act as a modulator protein for the P-ring assembly
BIND_RS18575	COG4786	Flagellar basal body rod
BIND_RS18580	COG1677	Flagellar hook-basal body complex protein FliE
BIND_RS18585	COG1558	bacterial-type flagellum-dependent cell motility
BIND_RS18595	COG1063	alcohol dehydrogenase
BIND_RS18600	COG0494	nUDIX hydrolase
BIND_RS18605	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BIND_RS18620	COG1999	signal sequence binding
BIND_RS18625	COG0523	cobalamin synthesis protein
BIND_RS18630	COG0667	Aldo Keto reductase
BIND_RS18650	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BIND_RS18655	COG1127	ABC transporter
BIND_RS18660	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BIND_RS18660	COG3218	ABC-type transport auxiliary lipoprotein component
BIND_RS18670	COG1230	cation diffusion facilitator family transporter
BIND_RS18685	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BIND_RS18695	COG3045	CreA protein
BIND_RS18720	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BIND_RS19070	COG4302	ethanolamine ammonia-lyase activity
BIND_RS19490	COG0443	Heat shock 70 kDa protein
BIND_RS19635	COG2096	Adenosyltransferase
BIND_RS19655	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BIND_RS19835	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BIND_RS19875	COG1215	transferase activity, transferring glycosyl groups
BIND_RS19920	COG1216	Glycosyl transferase, family 2
BIND_RS19935	COG2184	nucleotidyltransferase activity
BIND_RS19960	COG2205	protein histidine kinase activity
BIND_RS20065	COG3920	Histidine kinase
BIND_RS20140	COG4191	Histidine kinase
BIND_RS20145	COG1216	Glycosyl transferase, family 2
BIND_RS20145	COG1442	glycosyl transferase family 8
BIND_RS20150	COG0666	response to abiotic stimulus
BIND_RS20210	COG0732	type I restriction modification DNA specificity domain
BIND_RS20215	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BIND_RS20240	COG3034	peptidoglycan biosynthetic process
BIND_RS20300	COG3108	Peptidase M15
BIND_RS20320	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain