locus-tag	class	description
BCAV_RS00005	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BCAV_RS00010	COG0592	DNA-directed DNA polymerase activity
BCAV_RS00015	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BCAV_RS00020	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BCAV_RS00025	COG5512	Zn-ribbon-containing possibly RNA-binding protein and truncated derivatives
BCAV_RS00030	COG0187	DNA topoisomerase II activity
BCAV_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCAV_RS00075	COG1609	Transcriptional regulator
BCAV_RS00085	COG1175	transmembrane transport
BCAV_RS00090	COG0395	ABC-type sugar transport system, permease component
BCAV_RS00120	COG3764	Sortase (surface protein transpeptidase)
BCAV_RS00135	COG0515	serine threonine protein kinase
BCAV_RS00140	COG0515	serine threonine protein kinase
BCAV_RS00160	COG1716	ATPase activity
BCAV_RS00165	COG1716	ATPase activity
BCAV_RS00175	COG3655	Transcriptional regulator
BCAV_RS00205	COG0601	transmembrane transport
BCAV_RS00215	COG0444	Belongs to the ABC transporter superfamily
BCAV_RS00220	COG4172	Belongs to the ABC transporter superfamily
BCAV_RS00230	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCAV_RS00240	COG0778	Nitroreductase
BCAV_RS00250	COG1619	proteins homologs of microcin C7 resistance protein MccF
BCAV_RS00300	COG1653	transport
BCAV_RS00305	COG4209	transmembrane transport
BCAV_RS00310	COG0395	ABC-type sugar transport system, permease component
BCAV_RS00355	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BCAV_RS00390	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCAV_RS00390	COG0574	Belongs to the PEP-utilizing enzyme family
BCAV_RS00405	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BCAV_RS00460	COG2353	YceI-like domain
BCAV_RS00470	COG4989	oxidoreductase activity
BCAV_RS00490	COG1780	Probably involved in ribonucleotide reductase function
BCAV_RS00495	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCAV_RS00505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BCAV_RS00520	COG2197	response regulator
BCAV_RS00525	COG4585	Histidine kinase
BCAV_RS00540	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCAV_RS00575	COG0726	polysaccharide deacetylase
BCAV_RS00580	COG0402	S-adenosylhomocysteine deaminase activity
BCAV_RS00585	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCAV_RS00615	COG0673	inositol 2-dehydrogenase activity
BCAV_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS00625	COG2186	Transcriptional regulator
BCAV_RS00640	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS00650	COG1175	transmembrane transport
BCAV_RS00655	COG0395	ABC-type sugar transport system, permease component
BCAV_RS00665	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BCAV_RS00670	COG0519	Catalyzes the synthesis of GMP from XMP
BCAV_RS00680	COG3537	Alpha-1,2-mannosidase
BCAV_RS00710	COG1120	ATPase activity
BCAV_RS00715	COG4779	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCAV_RS00720	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCAV_RS00725	COG4592	Periplasmic binding protein
BCAV_RS00740	COG1175	transmembrane transport
BCAV_RS00765	COG1737	Transcriptional regulator
BCAV_RS00780	COG0596	Alpha beta hydrolase
BCAV_RS00820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS00825	COG0601	transmembrane transport
BCAV_RS00830	COG0747	negative chemotaxis
BCAV_RS00835	COG1396	sequence-specific DNA binding
BCAV_RS00850	COG0667	Aldo Keto reductase
BCAV_RS00890	COG3119	arylsulfatase activity
BCAV_RS00900	COG1175	transmembrane transport
BCAV_RS00905	COG0395	ABC-type sugar transport system, permease component
BCAV_RS00920	COG3387	PFAM Glycoside hydrolase 15-related
BCAV_RS00945	COG0673	inositol 2-dehydrogenase activity
BCAV_RS00955	COG0395	ABC-type sugar transport system, permease component
BCAV_RS00960	COG1175	transmembrane transport
BCAV_RS00970	COG1609	Transcriptional regulator
BCAV_RS00975	COG3075	Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses fumarate or nitrate as electron acceptor
BCAV_RS00985	COG0129	dihydroxy-acid dehydratase activity
BCAV_RS00990	COG1063	alcohol dehydrogenase
BCAV_RS01030	COG0596	Alpha beta hydrolase
BCAV_RS01050	COG1012	belongs to the aldehyde dehydrogenase family
BCAV_RS01055	COG1012	belongs to the aldehyde dehydrogenase family
BCAV_RS01090	COG0789	Transcriptional regulator
BCAV_RS01095	COG2813	Specifically methylates the guanine in position
BCAV_RS01100	COG3273	potassium ion transport
BCAV_RS01100	COG0471	metal ion transport
BCAV_RS01110	COG0628	permease
BCAV_RS01130	COG5002	protein histidine kinase activity
BCAV_RS01145	COG1643	Atp-dependent helicase
BCAV_RS01160	COG3386	PFAM SMP-30 Gluconolaconase
BCAV_RS01175	COG2814	Major facilitator Superfamily
BCAV_RS01180	COG4585	Histidine kinase
BCAV_RS01185	COG2197	response regulator
BCAV_RS01240	COG2318	DinB family
BCAV_RS01290	COG1309	transcriptional regulator
BCAV_RS01335	COG2409	Drug exporters of the RND superfamily
BCAV_RS01355	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BCAV_RS01365	COG1793	dna ligase
BCAV_RS01375	COG2233	PERMEase
BCAV_RS01390	COG1175	transmembrane transport
BCAV_RS01400	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCAV_RS01405	COG1609	Transcriptional regulator
BCAV_RS01435	COG2197	response regulator
BCAV_RS01440	COG4585	Histidine kinase
BCAV_RS01450	COG1131	(ABC) transporter
BCAV_RS01465	COG0166	Belongs to the GPI family
BCAV_RS01470	COG0657	acetylesterase activity
BCAV_RS01485	COG2197	response regulator
BCAV_RS01535	COG1175	transmembrane transport
BCAV_RS01540	COG0395	ABC-type sugar transport system, permease component
BCAV_RS01555	COG1175	transmembrane transport
BCAV_RS01560	COG0395	ABC-type sugar transport system, permease component
BCAV_RS01585	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCAV_RS01600	COG0395	ABC-type sugar transport system, permease component
BCAV_RS01605	COG1175	transmembrane transport
BCAV_RS01660	COG2318	DinB family
BCAV_RS01675	COG2197	response regulator
BCAV_RS01695	COG2205	protein histidine kinase activity
BCAV_RS01705	COG1215	transferase activity, transferring glycosyl groups
BCAV_RS01720	COG0640	Transcriptional regulator
BCAV_RS01730	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BCAV_RS01825	COG3265	gluconokinase activity
BCAV_RS01835	COG0028	Belongs to the TPP enzyme family
BCAV_RS01840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BCAV_RS01850	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
BCAV_RS01875	COG1215	transferase activity, transferring glycosyl groups
BCAV_RS01885	COG0077	Prephenate dehydratase
BCAV_RS01890	COG1597	lipid kinase activity
BCAV_RS01895	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BCAV_RS01900	COG0561	phosphatase activity
BCAV_RS01910	COG4941	Belongs to the sigma-70 factor family
BCAV_RS01950	COG3119	arylsulfatase activity
BCAV_RS01955	COG2746	aminoglycoside 3-N-acetyltransferase activity
BCAV_RS01980	COG1595	DNA-templated transcription, initiation
BCAV_RS02000	COG1595	DNA-templated transcription, initiation
BCAV_RS02010	COG2814	Major facilitator Superfamily
BCAV_RS02030	COG4585	Histidine kinase
BCAV_RS02090	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCAV_RS02095	COG1595	DNA-templated transcription, initiation
BCAV_RS02105	COG1464	Belongs to the NlpA lipoprotein family
BCAV_RS02110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCAV_RS02115	COG2011	ABC-type metal ion transport system permease component
BCAV_RS02125	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCAV_RS02130	COG0667	Aldo Keto reductase
BCAV_RS02140	COG0431	NADPH-dependent FMN reductase
BCAV_RS02170	COG2188	Transcriptional regulator
BCAV_RS02175	COG1653	transport
BCAV_RS02180	COG1175	transmembrane transport
BCAV_RS02185	COG0395	ABC-type sugar transport system, permease component
BCAV_RS02190	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BCAV_RS02195	COG1940	carbohydrate kinase activity
BCAV_RS02205	COG3189	MarR family transcriptional regulator
BCAV_RS02215	COG1136	(ABC) transporter
BCAV_RS02255	COG0477	Major facilitator Superfamily
BCAV_RS02265	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BCAV_RS02275	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCAV_RS02305	COG0577	efflux transmembrane transporter activity
BCAV_RS02305	COG1136	(ABC) transporter
BCAV_RS02340	COG0405	Gamma-glutamyltransferase
BCAV_RS02350	COG0477	Major facilitator Superfamily
BCAV_RS02365	COG0747	negative chemotaxis
BCAV_RS02385	COG3507	Belongs to the glycosyl hydrolase 43 family
BCAV_RS02390	COG2514	catechol 2,3-dioxygenase activity
BCAV_RS02395	COG0823	Involved in the tonB-independent uptake of proteins
BCAV_RS02405	COG2318	DinB family
BCAV_RS02420	COG1793	dna ligase
BCAV_RS02430	COG1131	(ABC) transporter
BCAV_RS02445	COG3845	ABC transporter
BCAV_RS02450	COG2188	Transcriptional regulator
BCAV_RS02460	COG3022	response to hydroperoxide
BCAV_RS02470	COG2814	Major facilitator Superfamily
BCAV_RS02500	COG1254	Belongs to the acylphosphatase family
BCAV_RS02505	COG0259	pyridoxamine-phosphate oxidase activity
BCAV_RS02515	COG0477	Major facilitator Superfamily
BCAV_RS02560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BCAV_RS02590	COG3304	Inner membrane component domain
BCAV_RS02595	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
BCAV_RS02600	COG0300	oxidoreductase activity
BCAV_RS02610	COG0590	tRNA wobble adenosine to inosine editing
BCAV_RS02645	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCAV_RS02650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BCAV_RS02680	COG0456	acetyltransferase
BCAV_RS02705	COG3559	Exporter of polyketide antibiotics
BCAV_RS02710	COG1131	(ABC) transporter
BCAV_RS02715	COG1309	transcriptional regulator
BCAV_RS02745	COG1473	amidohydrolase
BCAV_RS02765	COG1131	(ABC) transporter
BCAV_RS02775	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BCAV_RS02790	COG1131	(ABC) transporter
BCAV_RS02800	COG0395	ABC-type sugar transport system, permease component
BCAV_RS02845	COG2814	Major facilitator Superfamily
BCAV_RS02870	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BCAV_RS02875	COG3119	arylsulfatase activity
BCAV_RS02890	COG1653	transport
BCAV_RS02895	COG2390	Transcriptional regulator
BCAV_RS02910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BCAV_RS02920	COG2271	Major facilitator Superfamily
BCAV_RS02925	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCAV_RS02930	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
BCAV_RS02940	COG2271	Major facilitator Superfamily
BCAV_RS02950	COG2186	Transcriptional regulator
BCAV_RS02960	COG2267	carboxylic ester hydrolase activity
BCAV_RS02970	COG2197	response regulator
BCAV_RS02975	COG4585	Histidine kinase
BCAV_RS02980	COG2721	sulfolactate sulfo-lyase activity
BCAV_RS02985	COG0363	glucosamine-6-phosphate deaminase activity
BCAV_RS02995	COG1609	Transcriptional regulator
BCAV_RS03000	COG0673	inositol 2-dehydrogenase activity
BCAV_RS03005	COG4166	transmembrane transport
BCAV_RS03010	COG0601	transmembrane transport
BCAV_RS03015	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS03030	COG0673	inositol 2-dehydrogenase activity
BCAV_RS03035	COG0246	Mannitol dehydrogenase
BCAV_RS03050	COG1408	metallophosphoesterase
BCAV_RS03055	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BCAV_RS03065	COG0251	oxidation-reduction process
BCAV_RS03080	COG2267	carboxylic ester hydrolase activity
BCAV_RS03085	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BCAV_RS03110	COG0784	Response regulator, receiver
BCAV_RS03110	COG4191	Histidine kinase
BCAV_RS03150	COG1111	helicase
BCAV_RS03150	COG1205	dead DEAH box helicase
BCAV_RS03165	COG1366	Belongs to the anti-sigma-factor antagonist family
BCAV_RS03175	COG0018	arginyl-trna synthetase
BCAV_RS03195	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BCAV_RS03235	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS03240	COG3717	Catalyzes the isomerization of 5-dehydro-4-deoxy-D- glucuronate to 3-deoxy-D-glycero-2,5-hexodiulosonate
BCAV_RS03250	COG1414	Transcriptional regulator
BCAV_RS03255	COG0395	ABC-type sugar transport system, permease component
BCAV_RS03260	COG1175	transmembrane transport
BCAV_RS03265	COG2182	Extracellular solute-binding protein
BCAV_RS03285	COG1273	With LigD forms a non-homologous end joining (NHEJ) DNA repair enzyme, which repairs dsDNA breaks with reduced fidelity. Binds linear dsDNA with 5'- and 3'- overhangs but not closed circular dsDNA nor ssDNA. Recruits and stimulates the ligase activity of LigD
BCAV_RS03290	COG1793	dna ligase
BCAV_RS03290	COG3285	dna ligase
BCAV_RS03310	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BCAV_RS03310	COG1754	DNA topoisomerase type I activity
BCAV_RS03320	COG2318	DinB family
BCAV_RS03335	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BCAV_RS03360	COG1742	UPF0060 membrane protein
BCAV_RS03370	COG1278	Cold shock
BCAV_RS03415	COG0667	Aldo Keto reductase
BCAV_RS03455	COG0247	lactate metabolic process
BCAV_RS03455	COG0277	FAD linked oxidase domain protein
BCAV_RS03480	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCAV_RS03500	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BCAV_RS03520	COG0037	tRNA processing
BCAV_RS03530	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BCAV_RS03535	COG0302	gtp cyclohydrolase
BCAV_RS03540	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BCAV_RS03545	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BCAV_RS03605	COG2197	response regulator
BCAV_RS03620	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BCAV_RS03635	COG2188	Transcriptional regulator
BCAV_RS03650	COG3718	enzyme involved in inositol metabolism
BCAV_RS03655	COG3962	Belongs to the TPP enzyme family
BCAV_RS03670	COG0673	inositol 2-dehydrogenase activity
BCAV_RS03675	COG0588	phosphoglycerate mutase activity
BCAV_RS03720	COG2318	DinB family
BCAV_RS03735	COG2015	COG2015, Alkyl sulfatase and related hydrolases
BCAV_RS03740	COG2909	trisaccharide binding
BCAV_RS03790	COG0583	DNA-binding transcription factor activity
BCAV_RS03810	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCAV_RS03855	COG0704	Plays a role in the regulation of phosphate uptake
BCAV_RS03860	COG5002	protein histidine kinase activity
BCAV_RS03865	COG0745	RESPONSE REGULATOR receiver
BCAV_RS03880	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BCAV_RS03885	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BCAV_RS03895	COG1132	(ABC) transporter
BCAV_RS03910	COG0215	cysteine-tRNA ligase activity
BCAV_RS03930	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCAV_RS03935	COG3842	ATPase activity
BCAV_RS03945	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS03950	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS03960	COG0673	inositol 2-dehydrogenase activity
BCAV_RS03965	COG0395	ABC-type sugar transport system, permease component
BCAV_RS03970	COG1175	transmembrane transport
BCAV_RS04015	COG1609	Transcriptional regulator
BCAV_RS04015	COG2207	Transcriptional regulator
BCAV_RS04020	COG1175	transmembrane transport
BCAV_RS04025	COG0395	ABC-type sugar transport system, permease component
BCAV_RS04030	COG0673	inositol 2-dehydrogenase activity
BCAV_RS04050	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS04065	COG1506	peptidase
BCAV_RS04065	COG0823	Involved in the tonB-independent uptake of proteins
BCAV_RS04065	COG4946	Tricorn protease homolog
BCAV_RS04095	COG0579	oxidoreductase
BCAV_RS04120	COG0459	protein refolding
BCAV_RS04130	COG1285	pathogenesis
BCAV_RS04135	COG2905	signal-transduction protein containing cAMP-binding and CBS domains
BCAV_RS04140	COG1609	Transcriptional regulator
BCAV_RS04145	COG1621	beta-fructofuranosidase activity
BCAV_RS04150	COG0395	ABC-type sugar transport system, permease component
BCAV_RS04155	COG1175	transmembrane transport
BCAV_RS04175	COG3467	pyridoxamine 5'-phosphate
BCAV_RS04190	COG1063	alcohol dehydrogenase
BCAV_RS04195	COG0156	8-amino-7-oxononanoate synthase activity
BCAV_RS04210	COG2205	protein histidine kinase activity
BCAV_RS04215	COG0745	RESPONSE REGULATOR receiver
BCAV_RS04225	COG1842	Phage shock protein A
BCAV_RS04240	COG2814	Major facilitator Superfamily
BCAV_RS04245	COG1061	Type III restriction enzyme res subunit
BCAV_RS04255	COG1278	Cold shock
BCAV_RS04285	COG0745	RESPONSE REGULATOR receiver
BCAV_RS04315	COG1482	cell wall glycoprotein biosynthetic process
BCAV_RS04335	COG2252	PERMEase
BCAV_RS04350	COG1012	belongs to the aldehyde dehydrogenase family
BCAV_RS04355	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS04360	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCAV_RS04390	COG2814	Major facilitator Superfamily
BCAV_RS04415	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BCAV_RS04450	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCAV_RS04455	COG1834	amidinotransferase
BCAV_RS04470	COG1011	Hydrolase
BCAV_RS04485	COG1609	Transcriptional regulator
BCAV_RS04490	COG0584	glycerophosphoryl diester phosphodiesterase
BCAV_RS04495	COG1653	transport
BCAV_RS04500	COG0395	ABC-type sugar transport system, permease component
BCAV_RS04505	COG1175	transmembrane transport
BCAV_RS04510	COG0477	Major facilitator Superfamily
BCAV_RS04525	COG1970	mechanosensitive ion channel activity
BCAV_RS04570	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS04575	COG1653	transport
BCAV_RS04580	COG1175	transmembrane transport
BCAV_RS04585	COG0395	ABC-type sugar transport system, permease component
BCAV_RS04630	COG1175	transmembrane transport
BCAV_RS04635	COG0395	ABC-type sugar transport system, permease component
BCAV_RS04675	COG0667	Aldo Keto reductase
BCAV_RS04695	COG1104	cysteine desulfurase activity
BCAV_RS04700	COG0435	Glutathione S-transferase
BCAV_RS04715	COG2207	Transcriptional regulator
BCAV_RS04715	COG3708	Transcriptional regulator
BCAV_RS04720	COG0457	Tetratricopeptide repeat
BCAV_RS04735	COG1175	transmembrane transport
BCAV_RS04740	COG0395	ABC-type sugar transport system, permease component
BCAV_RS04790	COG0489	protein tyrosine kinase activity
BCAV_RS04820	COG1335	isochorismatase
BCAV_RS04825	COG0436	Aminotransferase
BCAV_RS04830	COG3483	tryptophan 2,3-dioxygenase activity
BCAV_RS04855	COG2133	pyrroloquinoline quinone binding
BCAV_RS04865	COG2409	Drug exporters of the RND superfamily
BCAV_RS04880	COG0142	geranyltranstransferase activity
BCAV_RS04885	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCAV_RS04890	COG0084	hydrolase, TatD family'
BCAV_RS04900	COG3583	domain protein
BCAV_RS04905	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BCAV_RS04910	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BCAV_RS04915	COG0488	(ABC) transporter
BCAV_RS04930	COG1846	Transcriptional regulator
BCAV_RS04945	COG1725	Transcriptional regulator
BCAV_RS04960	COG1215	transferase activity, transferring glycosyl groups
BCAV_RS04965	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCAV_RS04980	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BCAV_RS04985	COG0193	aminoacyl-tRNA hydrolase activity
BCAV_RS04995	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BCAV_RS04995	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BCAV_RS05050	COG0489	protein tyrosine kinase activity
BCAV_RS05065	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCAV_RS05070	COG0463	Glycosyl transferase, family 2
BCAV_RS05085	COG1132	(ABC) transporter
BCAV_RS05115	COG0588	phosphoglycerate mutase activity
BCAV_RS05125	COG0148	phosphopyruvate hydratase activity
BCAV_RS05140	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCAV_RS05155	COG0346	lactoylglutathione lyase activity
BCAV_RS05180	COG1252	NADH dehydrogenase
BCAV_RS05230	COG1090	epimerase
BCAV_RS05250	COG2217	Heavy metal translocating P-type atpase
BCAV_RS05285	COG2197	response regulator
BCAV_RS05290	COG4585	Histidine kinase
BCAV_RS05325	COG0640	Transcriptional regulator
BCAV_RS05330	COG3458	cephalosporin-C deacetylase activity
BCAV_RS05335	COG0477	Major facilitator Superfamily
BCAV_RS05345	COG2318	DinB family
BCAV_RS05360	COG0640	Transcriptional regulator
BCAV_RS05365	COG1387	Histidinol phosphatase and related hydrolases of the PHP family
BCAV_RS05365	COG1796	DNA polymerase
BCAV_RS05410	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCAV_RS05415	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BCAV_RS05420	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BCAV_RS05435	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCAV_RS05445	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BCAV_RS05450	COG2326	polyphosphate kinase activity
BCAV_RS05460	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCAV_RS05465	COG1875	ATPase related to phosphate starvation-inducible protein PhoH
BCAV_RS05475	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BCAV_RS05480	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BCAV_RS05485	COG3253	May function as heme-dependent peroxidase
BCAV_RS05490	COG1309	transcriptional regulator
BCAV_RS05510	COG0288	reversible hydration of carbon dioxide
BCAV_RS05540	COG1722	exodeoxyribonuclease VII activity
BCAV_RS05545	COG1570	exodeoxyribonuclease VII activity
BCAV_RS05555	COG1322	Protein conserved in bacteria
BCAV_RS05565	COG0012	GTP binding
BCAV_RS05610	COG2346	COG2346, Truncated hemoglobins
BCAV_RS05650	COG1217	gtp-binding protein TYPA
BCAV_RS05660	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
BCAV_RS05675	COG2720	vancomycin resistance protein
BCAV_RS05705	COG2171	N-acyltransferase activity
BCAV_RS05730	COG4770	biotin carboxylase activity
BCAV_RS05745	COG0424	maF-like protein
BCAV_RS05775	COG0673	inositol 2-dehydrogenase activity
BCAV_RS05785	COG1309	transcriptional regulator
BCAV_RS05800	COG0351	phosphomethylpyrimidine kinase
BCAV_RS05810	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCAV_RS05825	COG0745	RESPONSE REGULATOR receiver
BCAV_RS05830	COG2205	protein histidine kinase activity
BCAV_RS05845	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BCAV_RS05855	COG1215	transferase activity, transferring glycosyl groups
BCAV_RS05860	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCAV_RS05860	COG4124	Belongs to the glycosyl hydrolase 26 family
BCAV_RS05865	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BCAV_RS05870	COG1832	CoA-binding protein
BCAV_RS05875	COG1316	TRANSCRIPTIONal
BCAV_RS05885	COG1316	TRANSCRIPTIONal
BCAV_RS05890	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCAV_RS05910	COG1482	cell wall glycoprotein biosynthetic process
BCAV_RS05915	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BCAV_RS05940	COG0463	Glycosyl transferase, family 2
BCAV_RS05950	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
BCAV_RS05955	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCAV_RS05965	COG0673	inositol 2-dehydrogenase activity
BCAV_RS05975	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BCAV_RS05985	COG0579	oxidoreductase
BCAV_RS05995	COG1088	dTDP-glucose 4,6-dehydratase activity
BCAV_RS06000	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BCAV_RS06010	COG1442	glycosyl transferase family 8
BCAV_RS06010	COG1216	Glycosyl transferase, family 2
BCAV_RS06025	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
BCAV_RS06030	COG0381	UDP-N-acetylglucosamine 2-epimerase activity
BCAV_RS06035	COG1216	Glycosyl transferase, family 2
BCAV_RS06035	COG1442	glycosyl transferase family 8
BCAV_RS06040	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BCAV_RS06045	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BCAV_RS06050	COG0438	transferase activity, transferring glycosyl groups
BCAV_RS06055	COG0500	methyltransferase
BCAV_RS06125	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCAV_RS06135	COG2835	tetraacyldisaccharide 4'-kinase activity
BCAV_RS06140	COG1216	Glycosyl transferase, family 2
BCAV_RS06180	COG0517	IMP dehydrogenase activity
BCAV_RS06180	COG4175	Glycine betaine
BCAV_RS06215	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BCAV_RS06235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BCAV_RS06245	COG0745	RESPONSE REGULATOR receiver
BCAV_RS06250	COG5002	protein histidine kinase activity
BCAV_RS06250	COG5000	phosphorelay sensor kinase activity
BCAV_RS06255	COG5401	PFAM Sporulation and spore germination
BCAV_RS06265	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BCAV_RS06270	COG3214	Protein conserved in bacteria
BCAV_RS06275	COG0653	protein targeting
BCAV_RS06350	COG0483	inositol monophosphate 1-phosphatase activity
BCAV_RS06370	COG1595	DNA-templated transcription, initiation
BCAV_RS06405	COG0567	Dehydrogenase, E1 component
BCAV_RS06405	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCAV_RS06410	COG2205	protein histidine kinase activity
BCAV_RS06415	COG0745	RESPONSE REGULATOR receiver
BCAV_RS06425	COG2017	converts alpha-aldose to the beta-anomer
BCAV_RS06440	COG0019	diaminopimelate decarboxylase activity
BCAV_RS06445	COG0460	homoserine dehydrogenase
BCAV_RS06450	COG0498	Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine
BCAV_RS06465	COG0254	rRNA binding
BCAV_RS06470	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BCAV_RS06490	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCAV_RS06500	COG3525	Glycosyl hydrolase, family 20, catalytic domain
BCAV_RS06505	COG3540	Alkaline phosphatase
BCAV_RS06515	COG1653	transport
BCAV_RS06520	COG1175	transmembrane transport
BCAV_RS06530	COG1233	COG1233 Phytoene dehydrogenase and related
BCAV_RS06535	COG3119	arylsulfatase activity
BCAV_RS06540	COG0356	it plays a direct role in the translocation of protons across the membrane
BCAV_RS06550	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BCAV_RS06555	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BCAV_RS06560	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BCAV_RS06565	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BCAV_RS06570	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BCAV_RS06575	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BCAV_RS06585	COG1637	Cleaves both 3' and 5' ssDNA extremities of branched DNA structures
BCAV_RS06605	COG1820	Belongs to the metallo-dependent hydrolases superfamily. NagA family
BCAV_RS06620	COG1609	Transcriptional regulator
BCAV_RS06625	COG1472	Belongs to the glycosyl hydrolase 3 family
BCAV_RS06635	COG4209	transmembrane transport
BCAV_RS06640	COG0395	ABC-type sugar transport system, permease component
BCAV_RS06650	COG1501	Belongs to the glycosyl hydrolase 31 family
BCAV_RS06665	COG0488	(ABC) transporter
BCAV_RS06670	COG0596	Alpha beta hydrolase
BCAV_RS06710	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BCAV_RS06725	COG0366	Alpha amylase catalytic
BCAV_RS06740	COG0180	Tryptophanyl-tRNA synthetase
BCAV_RS06775	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BCAV_RS06780	COG1737	Transcriptional regulator
BCAV_RS06790	COG1940	carbohydrate kinase activity
BCAV_RS06795	COG1129	ABC transporter
BCAV_RS06800	COG1172	Belongs to the binding-protein-dependent transport system permease family
BCAV_RS06805	COG1879	ABC-type sugar transport system periplasmic component
BCAV_RS06835	COG2197	response regulator
BCAV_RS06840	COG4585	Histidine kinase
BCAV_RS06855	COG0482	sulfurtransferase activity
BCAV_RS06865	COG2329	Antibiotic biosynthesis monooxygenase
BCAV_RS06880	COG0477	Major facilitator Superfamily
BCAV_RS06910	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BCAV_RS06920	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BCAV_RS06930	COG1984	allophanate hydrolase subunit 2
BCAV_RS06940	COG1819	glycosyl
BCAV_RS06950	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCAV_RS06955	COG0154	amidase activity
BCAV_RS06960	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BCAV_RS06975	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCAV_RS06980	COG1121	(ABC) transporter
BCAV_RS06985	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCAV_RS06990	COG1321	iron dependent repressor
BCAV_RS07000	COG3876	Protein conserved in bacteria
BCAV_RS07005	COG1737	Transcriptional regulator
BCAV_RS07015	COG0456	acetyltransferase
BCAV_RS07030	COG0601	transmembrane transport
BCAV_RS07035	COG0444	Belongs to the ABC transporter superfamily
BCAV_RS07040	COG4608	Belongs to the ABC transporter superfamily
BCAV_RS07045	COG1472	Belongs to the glycosyl hydrolase 3 family
BCAV_RS07055	COG0129	dihydroxy-acid dehydratase activity
BCAV_RS07065	COG0129	dihydroxy-acid dehydratase activity
BCAV_RS07070	COG2154	pterin-4-alpha-carbinolamine dehydratase
BCAV_RS07095	COG0440	acetolactate synthase activity
BCAV_RS07100	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BCAV_RS07105	COG0657	acetylesterase activity
BCAV_RS07110	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BCAV_RS07135	COG0473	3-isopropylmalate dehydrogenase activity
BCAV_RS07140	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BCAV_RS07160	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCAV_RS07170	COG3634	alkyl hydroperoxide reductase activity
BCAV_RS07220	COG2186	Transcriptional regulator
BCAV_RS07225	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS07240	COG4209	transmembrane transport
BCAV_RS07245	COG0395	ABC-type sugar transport system, permease component
BCAV_RS07255	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BCAV_RS07290	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCAV_RS07305	COG0402	S-adenosylhomocysteine deaminase activity
BCAV_RS07315	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS07320	COG2182	Extracellular solute-binding protein
BCAV_RS07325	COG1175	transmembrane transport
BCAV_RS07330	COG0395	ABC-type sugar transport system, permease component
BCAV_RS07340	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCAV_RS07350	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS07355	COG0737	Belongs to the 5'-nucleotidase family
BCAV_RS07380	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCAV_RS07385	COG0673	inositol 2-dehydrogenase activity
BCAV_RS07395	COG1175	transmembrane transport
BCAV_RS07400	COG0395	ABC-type sugar transport system, permease component
BCAV_RS07410	COG1397	ADP-ribosylglycohydrolase
BCAV_RS07465	COG3833	ABC-type maltose transport systems, permease component
BCAV_RS07470	COG1175	transmembrane transport
BCAV_RS07480	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS07485	COG0148	phosphopyruvate hydratase activity
BCAV_RS07495	COG1063	alcohol dehydrogenase
BCAV_RS07505	COG1940	carbohydrate kinase activity
BCAV_RS07545	COG0537	adenosine 5'-monophosphoramidase activity
BCAV_RS07570	COG0647	UMP catabolic process
BCAV_RS07575	COG0698	ribose 5-phosphate isomerase
BCAV_RS07585	COG0395	ABC-type sugar transport system, permease component
BCAV_RS07595	COG0584	glycerophosphoryl diester phosphodiesterase
BCAV_RS07600	COG1069	ribulokinase activity
BCAV_RS07610	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS07625	COG3833	ABC-type maltose transport systems, permease component
BCAV_RS07630	COG1175	transmembrane transport
BCAV_RS07635	COG1802	Transcriptional regulator
BCAV_RS07650	COG1609	Transcriptional regulator
BCAV_RS07675	COG1132	(ABC) transporter
BCAV_RS07695	COG1175	transmembrane transport
BCAV_RS07705	COG0445	tRNA wobble uridine modification
BCAV_RS07710	COG0395	ABC-type sugar transport system, permease component
BCAV_RS07715	COG1175	transmembrane transport
BCAV_RS07725	COG1609	Transcriptional regulator
BCAV_RS07750	COG0656	L-ascorbic acid biosynthetic process
BCAV_RS07755	COG1175	transmembrane transport
BCAV_RS07760	COG0395	ABC-type sugar transport system, permease component
BCAV_RS07770	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS07775	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCAV_RS07785	COG2376	Dihydroxyacetone kinase
BCAV_RS07790	COG0698	ribose 5-phosphate isomerase
BCAV_RS07795	COG0149	triose-phosphate isomerase activity
BCAV_RS07820	COG4941	Belongs to the sigma-70 factor family
BCAV_RS07825	COG0577	efflux transmembrane transporter activity
BCAV_RS07825	COG1136	(ABC) transporter
BCAV_RS07830	COG1136	(ABC) transporter
BCAV_RS07830	COG0577	efflux transmembrane transporter activity
BCAV_RS07870	COG0179	Fumarylacetoacetate (FAA) hydrolase
BCAV_RS07875	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BCAV_RS07880	COG1011	Hydrolase
BCAV_RS07915	COG1074	ATP-dependent DNA helicase activity
BCAV_RS07920	COG1414	Transcriptional regulator
BCAV_RS07925	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BCAV_RS07930	COG0066	3-isopropylmalate dehydratase activity
BCAV_RS07935	COG2902	Dehydrogenase
BCAV_RS07950	COG1609	Transcriptional regulator
BCAV_RS07960	COG0395	ABC-type sugar transport system, permease component
BCAV_RS07965	COG4209	transmembrane transport
BCAV_RS07970	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCAV_RS07990	COG4585	Histidine kinase
BCAV_RS07995	COG2197	response regulator
BCAV_RS08005	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BCAV_RS08030	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCAV_RS08050	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BCAV_RS08060	COG1122	ATPase activity
BCAV_RS08075	COG0742	ribosomal rna small subunit methyltransferase
BCAV_RS08080	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BCAV_RS08095	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BCAV_RS08100	COG0571	ribonuclease III activity
BCAV_RS08105	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCAV_RS08125	COG1132	(ABC) transporter
BCAV_RS08130	COG4988	ABC transporter
BCAV_RS08135	COG1294	oxidase, subunit
BCAV_RS08140	COG1271	oxidase subunit
BCAV_RS08145	COG1530	ribonuclease E activity
BCAV_RS08155	COG3340	Belongs to the peptidase S51 family
BCAV_RS08165	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BCAV_RS08170	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BCAV_RS08175	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BCAV_RS08180	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BCAV_RS08185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCAV_RS08190	COG0800	Aldolase
BCAV_RS08220	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BCAV_RS08235	COG0799	negative regulation of ribosome biogenesis
BCAV_RS08240	COG0406	alpha-ribazole phosphatase activity
BCAV_RS08255	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
BCAV_RS08330	COG1940	carbohydrate kinase activity
BCAV_RS08335	COG1653	transport
BCAV_RS08340	COG1175	transmembrane transport
BCAV_RS08345	COG0395	ABC-type sugar transport system, permease component
BCAV_RS08350	COG0673	inositol 2-dehydrogenase activity
BCAV_RS08355	COG0673	inositol 2-dehydrogenase activity
BCAV_RS08390	COG1132	(ABC) transporter
BCAV_RS08395	COG2890	protein-(glutamine-N5) methyltransferase activity
BCAV_RS08400	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BCAV_RS08410	COG0037	tRNA processing
BCAV_RS08410	COG0590	tRNA wobble adenosine to inosine editing
BCAV_RS08425	COG1626	Provides the cells with the ability to utilize trehalose at high osmolarity by splitting it into glucose molecules that can subsequently be taken up by the phosphotransferase-mediated uptake system
BCAV_RS08430	COG1529	Aldehyde oxidase and xanthine dehydrogenase
BCAV_RS08435	COG2080	2 iron, 2 sulfur cluster binding
BCAV_RS08440	COG1319	Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM
BCAV_RS08445	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCAV_RS08465	COG1175	transmembrane transport
BCAV_RS08485	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS08495	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCAV_RS08530	COG0521	Mo-molybdopterin cofactor biosynthetic process
BCAV_RS08530	COG0315	cyclic pyranopterin monophosphate synthase activity
BCAV_RS08540	COG1609	Transcriptional regulator
BCAV_RS08555	COG1175	transmembrane transport
BCAV_RS08560	COG0395	ABC-type sugar transport system, permease component
BCAV_RS08565	COG4941	Belongs to the sigma-70 factor family
BCAV_RS08575	COG1869	D-ribose catabolic process
BCAV_RS08585	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCAV_RS08610	COG0395	ABC-type sugar transport system, permease component
BCAV_RS08670	COG1253	flavin adenine dinucleotide binding
BCAV_RS08685	COG0431	NADPH-dependent FMN reductase
BCAV_RS08710	COG0495	leucyl-tRNA aminoacylation
BCAV_RS08715	COG2197	response regulator
BCAV_RS08720	COG4585	Histidine kinase
BCAV_RS08740	COG0433	COG0433 Predicted ATPase
BCAV_RS08760	COG0268	Binds directly to 16S ribosomal RNA
BCAV_RS08780	COG0481	GTPase activity
BCAV_RS08805	COG1420	regulation of RNA biosynthetic process
BCAV_RS08810	COG0484	heat shock protein binding
BCAV_RS08820	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
BCAV_RS08825	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BCAV_RS08840	COG0631	protein serine/threonine phosphatase activity
BCAV_RS08850	COG0515	serine threonine protein kinase
BCAV_RS08865	COG0714	Associated with various cellular activities
BCAV_RS08885	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BCAV_RS08895	COG1381	Involved in DNA repair and RecF pathway recombination
BCAV_RS08900	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BCAV_RS08910	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BCAV_RS08915	COG1649	PFAM Uncharacterised BCR, COG1649
BCAV_RS08930	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BCAV_RS08935	COG1121	(ABC) transporter
BCAV_RS08940	COG3443	Belongs to the bacterial solute-binding protein 9 family
BCAV_RS08940	COG0803	Belongs to the bacterial solute-binding protein 9 family
BCAV_RS08945	COG0423	glycine-tRNA ligase activity
BCAV_RS08975	COG1175	transmembrane transport
BCAV_RS08980	COG3833	ABC-type maltose transport systems, permease component
BCAV_RS08990	COG0366	Alpha amylase catalytic
BCAV_RS09005	COG0358	DNA primase activity
BCAV_RS09045	COG4172	Belongs to the ABC transporter superfamily
BCAV_RS09050	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS09060	COG0747	negative chemotaxis
BCAV_RS09100	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BCAV_RS09105	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BCAV_RS09125	COG2609	component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2)
BCAV_RS09180	COG2197	response regulator
BCAV_RS09230	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCAV_RS09250	COG3022	response to hydroperoxide
BCAV_RS09255	COG0010	Belongs to the arginase family
BCAV_RS09265	COG2986	histidine ammonia-lyase
BCAV_RS09270	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
BCAV_RS09275	COG1228	amidohydrolase
BCAV_RS09315	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BCAV_RS09325	COG0174	glutamine synthetase
BCAV_RS09330	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BCAV_RS09335	COG2197	response regulator
BCAV_RS09350	COG0174	glutamine synthetase
BCAV_RS09365	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BCAV_RS09370	COG0321	lipoyl(octanoyl) transferase activity
BCAV_RS09375	COG0515	serine threonine protein kinase
BCAV_RS09380	COG1090	epimerase
BCAV_RS09385	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCAV_RS09390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BCAV_RS09410	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCAV_RS09410	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCAV_RS09420	COG2390	Transcriptional regulator
BCAV_RS09435	COG4209	transmembrane transport
BCAV_RS09440	COG0395	ABC-type sugar transport system, permease component
BCAV_RS09445	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCAV_RS09460	COG0167	dihydroorotate dehydrogenase activity
BCAV_RS09470	COG0667	Aldo Keto reductase
BCAV_RS09485	COG1929	Belongs to the glycerate kinase type-1 family
BCAV_RS09500	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
BCAV_RS09505	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
BCAV_RS09520	COG1290	Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis
BCAV_RS09525	COG0723	plastoquinol--plastocyanin reductase activity
BCAV_RS09530	COG2010	Cytochrome c
BCAV_RS09535	COG1845	cytochrome c oxidase, subunit III
BCAV_RS09545	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BCAV_RS09555	COG1012	belongs to the aldehyde dehydrogenase family
BCAV_RS09580	COG1022	Amp-dependent synthetase and ligase
BCAV_RS09585	COG1940	carbohydrate kinase activity
BCAV_RS09600	COG0205	6-phosphofructokinase activity
BCAV_RS09605	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BCAV_RS09615	COG2815	serine threonine protein kinase
BCAV_RS09615	COG0515	serine threonine protein kinase
BCAV_RS09630	COG0142	geranyltranstransferase activity
BCAV_RS09640	COG0589	response to stress
BCAV_RS09645	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BCAV_RS09650	COG0509	glycine decarboxylation via glycine cleavage system
BCAV_RS09655	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCAV_RS09655	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BCAV_RS09660	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BCAV_RS09685	COG0187	DNA topoisomerase II activity
BCAV_RS09695	COG0454	-acetyltransferase
BCAV_RS09695	COG0456	acetyltransferase
BCAV_RS09705	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCAV_RS09715	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BCAV_RS09720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BCAV_RS09720	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCAV_RS09735	COG1435	thymidine kinase activity
BCAV_RS09745	COG0483	inositol monophosphate 1-phosphatase activity
BCAV_RS09760	COG0756	dUTP diphosphatase activity
BCAV_RS09785	COG0569	domain protein
BCAV_RS09790	COG0531	amino acid
BCAV_RS09795	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BCAV_RS09800	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCAV_RS09805	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BCAV_RS09825	COG2860	membrane
BCAV_RS09835	COG3795	YCII-related domain
BCAV_RS09840	COG0395	ABC-type sugar transport system, permease component
BCAV_RS09855	COG1609	Transcriptional regulator
BCAV_RS09865	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BCAV_RS09875	COG1024	Enoyl-CoA hydratase
BCAV_RS09875	COG1250	3-hydroxyacyl-CoA dehydrogenase
BCAV_RS09880	COG0183	Belongs to the thiolase family
BCAV_RS09905	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BCAV_RS09905	COG2308	Evidence 4 Homologs of previously reported genes of
BCAV_RS09985	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS09995	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BCAV_RS10005	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCAV_RS10010	COG1560	Kdo2-lipid A biosynthetic process
BCAV_RS10015	COG0438	transferase activity, transferring glycosyl groups
BCAV_RS10030	COG0214	Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively
BCAV_RS10035	COG0494	nUDIX hydrolase
BCAV_RS10040	COG0311	Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS
BCAV_RS10045	COG0217	transcriptional regulatory protein
BCAV_RS10060	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BCAV_RS10065	COG0632	four-way junction helicase activity
BCAV_RS10070	COG2255	four-way junction helicase activity
BCAV_RS10080	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCAV_RS10085	COG0341	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BCAV_RS10090	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BCAV_RS10095	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BCAV_RS10105	COG1196	nuclear chromosome segregation
BCAV_RS10110	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BCAV_RS10115	COG0124	histidyl-tRNA synthetase
BCAV_RS10130	COG0436	Aminotransferase
BCAV_RS10135	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BCAV_RS10145	COG2409	Drug exporters of the RND superfamily
BCAV_RS10155	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BCAV_RS10170	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BCAV_RS10175	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BCAV_RS10185	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BCAV_RS10195	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BCAV_RS10200	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BCAV_RS10205	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
BCAV_RS10210	COG0640	Transcriptional regulator
BCAV_RS10225	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BCAV_RS10255	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BCAV_RS10260	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BCAV_RS10265	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
BCAV_RS10270	COG0540	Belongs to the ATCase OTCase family
BCAV_RS10275	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCAV_RS10290	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BCAV_RS10295	COG0284	orotidine-5'-phosphate decarboxylase activity
BCAV_RS10310	COG0194	GDP metabolic process
BCAV_RS10315	COG1758	RNA polymerase activity
BCAV_RS10325	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BCAV_RS10335	COG1011	Hydrolase
BCAV_RS10340	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BCAV_RS10350	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BCAV_RS10355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCAV_RS10360	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCAV_RS10365	COG0140	phosphoribosyl-ATP diphosphatase activity
BCAV_RS10370	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BCAV_RS10390	COG2378	regulation of single-species biofilm formation
BCAV_RS10405	COG0805	protein transport
BCAV_RS10425	COG1216	Glycosyl transferase, family 2
BCAV_RS10465	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BCAV_RS10490	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCAV_RS10510	COG2318	DinB family
BCAV_RS10540	COG4941	Belongs to the sigma-70 factor family
BCAV_RS10555	COG1262	PFAM Formylglycine-generating sulfatase enzyme
BCAV_RS10560	COG3119	arylsulfatase activity
BCAV_RS10570	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCAV_RS10575	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BCAV_RS10595	COG1716	ATPase activity
BCAV_RS10620	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCAV_RS10640	COG0328	RNA-DNA hybrid ribonuclease activity
BCAV_RS10690	COG3540	Alkaline phosphatase
BCAV_RS10705	COG0110	maltose O-acetyltransferase activity
BCAV_RS10710	COG3226	Transcriptional regulator
BCAV_RS10715	COG0667	Aldo Keto reductase
BCAV_RS10745	COG4977	sequence-specific DNA binding
BCAV_RS10800	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS10820	COG1160	GTP binding
BCAV_RS10830	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BCAV_RS10850	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BCAV_RS10865	COG1253	flavin adenine dinucleotide binding
BCAV_RS10880	COG0109	protoheme IX farnesyltransferase activity
BCAV_RS10890	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BCAV_RS10905	COG0363	glucosamine-6-phosphate deaminase activity
BCAV_RS10910	COG4122	O-methyltransferase activity
BCAV_RS10920	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BCAV_RS10925	COG0149	triose-phosphate isomerase activity
BCAV_RS10930	COG0126	phosphoglycerate kinase activity
BCAV_RS10940	COG1481	regulation of sporulation
BCAV_RS10950	COG1660	Displays ATPase and GTPase activities
BCAV_RS10955	COG0322	excinuclease ABC activity
BCAV_RS11000	COG0556	nucleotide-excision repair
BCAV_RS11015	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCAV_RS11015	COG0237	dephospho-CoA kinase activity
BCAV_RS11020	COG2197	response regulator
BCAV_RS11035	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BCAV_RS11045	COG0539	negative regulation of cytoplasmic translation
BCAV_RS11055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS11060	COG0601	transmembrane transport
BCAV_RS11065	COG0747	negative chemotaxis
BCAV_RS11075	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BCAV_RS11085	COG2050	protein possibly involved in aromatic compounds catabolism
BCAV_RS11130	COG4941	Belongs to the sigma-70 factor family
BCAV_RS11170	COG0069	glutamate synthase activity
BCAV_RS11170	COG0070	glutamate synthase
BCAV_RS11170	COG0067	glutamate synthase
BCAV_RS11175	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BCAV_RS11185	COG0133	tryptophan synthase activity
BCAV_RS11190	COG0134	indole-3-glycerol-phosphate synthase activity
BCAV_RS11235	COG1132	(ABC) transporter
BCAV_RS11255	COG0107	imidazoleglycerol-phosphate synthase activity
BCAV_RS11265	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BCAV_RS11270	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
BCAV_RS11280	COG4122	O-methyltransferase activity
BCAV_RS11290	COG1222	aaa ATPase
BCAV_RS11300	COG1994	Peptidase M50
BCAV_RS11300	COG0517	IMP dehydrogenase activity
BCAV_RS11305	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCAV_RS11315	COG0215	cysteine-tRNA ligase activity
BCAV_RS11325	COG1968	undecaprenyl-diphosphatase activity
BCAV_RS11330	COG0667	Aldo Keto reductase
BCAV_RS11345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCAV_RS11350	COG0339	signal peptide processing
BCAV_RS11360	COG3795	YCII-related domain
BCAV_RS11375	COG2211	Major facilitator Superfamily
BCAV_RS11385	COG0456	acetyltransferase
BCAV_RS11395	COG1609	Transcriptional regulator
BCAV_RS11410	COG0395	ABC-type sugar transport system, permease component
BCAV_RS11415	COG1063	alcohol dehydrogenase
BCAV_RS11420	COG0673	inositol 2-dehydrogenase activity
BCAV_RS11425	COG4942	peptidase
BCAV_RS11440	COG0395	ABC-type sugar transport system, permease component
BCAV_RS11445	COG1175	transmembrane transport
BCAV_RS11490	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BCAV_RS11515	COG0587	DNA-directed DNA polymerase activity
BCAV_RS11530	COG1881	PFAM PEBP family protein
BCAV_RS11540	COG2375	cellular response to nickel ion
BCAV_RS11555	COG1120	ATPase activity
BCAV_RS11560	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BCAV_RS11575	COG2011	ABC-type metal ion transport system permease component
BCAV_RS11580	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BCAV_RS11585	COG1464	Belongs to the NlpA lipoprotein family
BCAV_RS11650	COG1119	ATPase activity
BCAV_RS11660	COG0297	glycogen (starch) synthase activity
BCAV_RS11670	COG0560	Phosphoserine phosphatase
BCAV_RS11670	COG3830	Belongs to the UPF0237 family
BCAV_RS11685	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS11705	COG0488	(ABC) transporter
BCAV_RS11745	COG2151	metal-sulfur cluster biosynthetic enzyme
BCAV_RS11750	COG0822	iron-sulfur transferase activity
BCAV_RS11760	COG0396	ATPase activity
BCAV_RS11770	COG0719	Fe-S assembly protein
BCAV_RS11785	COG1131	(ABC) transporter
BCAV_RS11810	COG1612	heme a metabolic process
BCAV_RS11815	COG0494	nUDIX hydrolase
BCAV_RS11820	COG0504	CTP synthase activity
BCAV_RS11830	COG0728	peptidoglycan biosynthetic process
BCAV_RS11850	COG0497	DNA recombination
BCAV_RS11855	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BCAV_RS11865	COG0647	UMP catabolic process
BCAV_RS11895	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BCAV_RS11900	COG2094	Belongs to the DNA glycosylase MPG family
BCAV_RS11915	COG0165	Argininosuccinate lyase
BCAV_RS11920	COG0137	argininosuccinate synthase activity
BCAV_RS11925	COG1438	arginine binding
BCAV_RS11935	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BCAV_RS11940	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BCAV_RS11945	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BCAV_RS11950	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BCAV_RS11955	COG0604	alcohol dehydrogenase
BCAV_RS11965	COG0300	oxidoreductase activity
BCAV_RS11970	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BCAV_RS11970	COG0072	phenylalanine-tRNA ligase activity
BCAV_RS11975	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BCAV_RS11995	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BCAV_RS12000	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BCAV_RS12005	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BCAV_RS12010	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BCAV_RS12030	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BCAV_RS12035	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BCAV_RS12045	COG0131	Imidazoleglycerol-phosphate dehydratase
BCAV_RS12065	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BCAV_RS12080	COG0587	DNA-directed DNA polymerase activity
BCAV_RS12095	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BCAV_RS12100	COG3599	regulation of cell shape
BCAV_RS12110	COG1799	cell septum assembly
BCAV_RS12115	COG1496	oxidoreductase activity
BCAV_RS12120	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BCAV_RS12130	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BCAV_RS12135	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BCAV_RS12145	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BCAV_RS12150	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BCAV_RS12160	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BCAV_RS12165	COG0768	penicillin binding
BCAV_RS12175	COG0275	rRNA processing
BCAV_RS12180	COG2001	Belongs to the MraZ family
BCAV_RS12185	COG0714	Associated with various cellular activities
BCAV_RS12205	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BCAV_RS12215	COG1278	Cold shock
BCAV_RS12230	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCAV_RS12240	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BCAV_RS12250	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BCAV_RS12265	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BCAV_RS12275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BCAV_RS12280	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCAV_RS12295	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BCAV_RS12300	COG1126	abc transporter atp-binding protein
BCAV_RS12305	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BCAV_RS12310	COG0765	amino acid transport
BCAV_RS12315	COG0765	amino acid transport
BCAV_RS12320	COG2137	regulation of response to DNA damage stimulus
BCAV_RS12325	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
BCAV_RS12330	COG2197	response regulator
BCAV_RS12335	COG4585	Histidine kinase
BCAV_RS12350	COG1201	RNA secondary structure unwinding
BCAV_RS12355	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCAV_RS12360	COG1396	sequence-specific DNA binding
BCAV_RS12365	COG1546	Belongs to the CinA family
BCAV_RS12365	COG1058	Belongs to the CinA family
BCAV_RS12390	COG1674	ftsk spoiiie
BCAV_RS12410	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BCAV_RS12445	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BCAV_RS12455	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS12470	COG0612	Peptidase, M16
BCAV_RS12475	COG1185	polyribonucleotide nucleotidyltransferase activity
BCAV_RS12480	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BCAV_RS12495	COG2197	response regulator
BCAV_RS12500	COG4585	Histidine kinase
BCAV_RS12510	COG1136	(ABC) transporter
BCAV_RS12510	COG0577	efflux transmembrane transporter activity
BCAV_RS12520	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BCAV_RS12525	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BCAV_RS12530	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BCAV_RS12540	COG0195	Participates in both transcription termination and antitermination
BCAV_RS12545	COG0779	Required for maturation of 30S ribosomal subunits
BCAV_RS12555	COG0442	prolyl-tRNA aminoacylation
BCAV_RS12570	COG0456	acetyltransferase
BCAV_RS12575	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BCAV_RS12580	COG0750	zinc metalloprotease
BCAV_RS12585	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BCAV_RS12595	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BCAV_RS12600	COG0575	Belongs to the CDS family
BCAV_RS12605	COG0233	cytoplasmic translational termination
BCAV_RS12610	COG0528	UMP kinase activity
BCAV_RS12615	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BCAV_RS12620	COG0052	Belongs to the universal ribosomal protein uS2 family
BCAV_RS12675	COG1674	ftsk spoiiie
BCAV_RS12745	COG0606	chelatase, subunit chli
BCAV_RS12750	COG0792	nuclease activity
BCAV_RS12760	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BCAV_RS12765	COG0681	Belongs to the peptidase S26 family
BCAV_RS12770	COG0335	large ribosomal subunit rRNA binding
BCAV_RS12775	COG0336	Belongs to the RNA methyltransferase TrmD family
BCAV_RS12780	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BCAV_RS12785	COG1837	Belongs to the UPF0109 family
BCAV_RS12790	COG0228	four-way junction DNA binding
BCAV_RS12845	COG1175	transmembrane transport
BCAV_RS12850	COG0395	ABC-type sugar transport system, permease component
BCAV_RS12855	COG3842	ATPase activity
BCAV_RS12875	COG0105	UTP biosynthetic process
BCAV_RS12900	COG1461	Dihydroxyacetone kinase
BCAV_RS12920	COG0285	dihydrofolate synthase activity
BCAV_RS12945	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BCAV_RS12950	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BCAV_RS12955	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCAV_RS12965	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCAV_RS12975	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BCAV_RS12985	COG0531	amino acid
BCAV_RS13000	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCAV_RS13005	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BCAV_RS13015	COG1478	Catalyzes the GTP-dependent successive addition of multiple gamma-linked L-glutamates to the L-lactyl phosphodiester of 7,8-didemethyl-8-hydroxy-5-deazariboflavin (F420-0) to form polyglutamated F420 derivatives
BCAV_RS13015	COG0778	Nitroreductase
BCAV_RS13020	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCAV_RS13025	COG1486	melibiose metabolic process
BCAV_RS13030	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCAV_RS13040	COG1175	transmembrane transport
BCAV_RS13050	COG0525	valine-tRNA ligase activity
BCAV_RS13055	COG1022	Amp-dependent synthetase and ligase
BCAV_RS13060	COG0287	Prephenate dehydrogenase
BCAV_RS13060	COG1605	Chorismate mutase
BCAV_RS13065	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BCAV_RS13070	COG0740	serine-type endopeptidase activity
BCAV_RS13080	COG0544	peptidyl-prolyl cis-trans isomerase activity
BCAV_RS13085	COG3119	arylsulfatase activity
BCAV_RS13095	COG1175	transmembrane transport
BCAV_RS13100	COG2182	Extracellular solute-binding protein
BCAV_RS13105	COG1609	Transcriptional regulator
BCAV_RS13145	COG1045	serine acetyltransferase
BCAV_RS13150	COG2978	secondary active p-aminobenzoyl-glutamate transmembrane transporter activity
BCAV_RS13155	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCAV_RS13200	COG3590	peptidase
BCAV_RS13215	COG4552	Acetyltransferase involved in intracellular survival and related
BCAV_RS13225	COG1653	transport
BCAV_RS13230	COG1175	transmembrane transport
BCAV_RS13235	COG0395	ABC-type sugar transport system, permease component
BCAV_RS13240	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
BCAV_RS13250	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BCAV_RS13255	COG2190	(PTS) system
BCAV_RS13265	COG0668	transmembrane transport
BCAV_RS13270	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BCAV_RS13275	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCAV_RS13295	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCAV_RS13300	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCAV_RS13320	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BCAV_RS13365	COG0584	glycerophosphoryl diester phosphodiesterase
BCAV_RS13415	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCAV_RS13420	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BCAV_RS13430	COG0640	Transcriptional regulator
BCAV_RS13445	COG1125	glycine betaine transport
BCAV_RS13445	COG0517	IMP dehydrogenase activity
BCAV_RS13450	COG1174	glycine betaine transport
BCAV_RS13455	COG1174	glycine betaine transport
BCAV_RS13480	COG1737	Transcriptional regulator
BCAV_RS13485	COG3639	organic phosphonate transmembrane transporter activity
BCAV_RS13490	COG3639	organic phosphonate transmembrane transporter activity
BCAV_RS13495	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BCAV_RS13535	COG0702	epimerase
BCAV_RS13560	COG2197	response regulator
BCAV_RS13565	COG4585	Histidine kinase
BCAV_RS13575	COG1131	(ABC) transporter
BCAV_RS13585	COG3973	AAA domain
BCAV_RS13590	COG2267	carboxylic ester hydrolase activity
BCAV_RS13595	COG4106	trans-aconitate 2-methyltransferase activity
BCAV_RS13610	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS13615	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS13620	COG0395	ABC-type sugar transport system, permease component
BCAV_RS13625	COG0395	ABC-type sugar transport system, permease component
BCAV_RS13630	COG1653	transport
BCAV_RS13665	COG2197	response regulator
BCAV_RS13670	COG0477	Major facilitator Superfamily
BCAV_RS13685	COG0531	amino acid
BCAV_RS13700	COG0395	ABC-type sugar transport system, permease component
BCAV_RS13705	COG1175	transmembrane transport
BCAV_RS13715	COG1609	Transcriptional regulator
BCAV_RS13735	COG4608	Belongs to the ABC transporter superfamily
BCAV_RS13740	COG0444	Belongs to the ABC transporter superfamily
BCAV_RS13745	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS13750	COG0601	transmembrane transport
BCAV_RS13755	COG0747	negative chemotaxis
BCAV_RS13775	COG0488	(ABC) transporter
BCAV_RS13780	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BCAV_RS13785	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BCAV_RS13790	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BCAV_RS13795	COG1234	tRNA 3'-trailer cleavage
BCAV_RS13800	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BCAV_RS13820	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BCAV_RS13860	COG0363	glucosamine-6-phosphate deaminase activity
BCAV_RS13870	COG1131	(ABC) transporter
BCAV_RS13905	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BCAV_RS13930	COG3119	arylsulfatase activity
BCAV_RS13945	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BCAV_RS13950	COG0739	heme binding
BCAV_RS13955	COG2177	Part of the ABC transporter FtsEX involved in
BCAV_RS13960	COG2884	Cell division ATP-binding protein ftsE
BCAV_RS13965	COG0574	Belongs to the PEP-utilizing enzyme family
BCAV_RS13965	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BCAV_RS13970	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BCAV_RS13980	COG1104	cysteine desulfurase activity
BCAV_RS13990	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BCAV_RS13995	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BCAV_RS14010	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BCAV_RS14015	COG2814	Major facilitator Superfamily
BCAV_RS14030	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BCAV_RS14035	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
BCAV_RS14100	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BCAV_RS14100	COG1648	precorrin-2 dehydrogenase activity
BCAV_RS14105	COG2146	nitrite reductase [NAD(P)H] activity
BCAV_RS14105	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCAV_RS14110	COG2146	nitrite reductase [NAD(P)H] activity
BCAV_RS14110	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCAV_RS14115	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCAV_RS14120	COG0243	molybdopterin cofactor binding
BCAV_RS14125	COG2223	nitrite transmembrane transporter activity
BCAV_RS14135	COG1140	nitrate reductase beta subunit
BCAV_RS14140	COG2180	nitrate reductase molybdenum cofactor assembly chaperone
BCAV_RS14155	COG0746	molybdenum cofactor guanylyltransferase activity
BCAV_RS14190	COG1846	Transcriptional regulator
BCAV_RS14190	COG1940	carbohydrate kinase activity
BCAV_RS14200	COG1175	transmembrane transport
BCAV_RS14205	COG0395	ABC-type sugar transport system, permease component
BCAV_RS14215	COG2135	peptidase activity
BCAV_RS14220	COG4585	Histidine kinase
BCAV_RS14225	COG2197	response regulator
BCAV_RS14235	COG1136	(ABC) transporter
BCAV_RS14270	COG1823	symporter activity
BCAV_RS14275	COG0395	ABC-type sugar transport system, permease component
BCAV_RS14280	COG1175	transmembrane transport
BCAV_RS14310	COG0395	ABC-type sugar transport system, permease component
BCAV_RS14325	COG0584	glycerophosphoryl diester phosphodiesterase
BCAV_RS14335	COG1609	Transcriptional regulator
BCAV_RS14340	COG3842	ATPase activity
BCAV_RS14345	COG1653	transport
BCAV_RS14360	COG0647	UMP catabolic process
BCAV_RS14365	COG1012	belongs to the aldehyde dehydrogenase family
BCAV_RS14375	COG1247	-acetyltransferase
BCAV_RS14400	COG0656	L-ascorbic acid biosynthetic process
BCAV_RS14420	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCAV_RS14430	COG1929	Belongs to the glycerate kinase type-1 family
BCAV_RS14435	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BCAV_RS14450	COG1609	Transcriptional regulator
BCAV_RS14465	COG0714	Associated with various cellular activities
BCAV_RS14480	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BCAV_RS14485	COG0395	ABC-type sugar transport system, permease component
BCAV_RS14490	COG1175	transmembrane transport
BCAV_RS14500	COG1609	Transcriptional regulator
BCAV_RS14545	COG1615	UPF0182 protein
BCAV_RS14565	COG3480	Lon protease (S16) C-terminal proteolytic domain
BCAV_RS14595	COG1131	(ABC) transporter
BCAV_RS14600	COG3540	Alkaline phosphatase
BCAV_RS14620	COG3173	Aminoglycoside phosphotransferase
BCAV_RS14625	COG0210	DNA helicase
BCAV_RS14650	COG0513	Belongs to the DEAD box helicase family
BCAV_RS14655	COG0009	L-threonylcarbamoyladenylate synthase
BCAV_RS14660	COG2095	MarC family integral membrane protein
BCAV_RS14665	COG0613	PHP domain protein
BCAV_RS14670	COG0006	proline dipeptidase activity
BCAV_RS14685	COG2239	Acts as a magnesium transporter
BCAV_RS14715	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCAV_RS14725	COG1595	DNA-templated transcription, initiation
BCAV_RS14740	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BCAV_RS14755	COG1611	Belongs to the LOG family
BCAV_RS14760	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BCAV_RS14770	COG0488	(ABC) transporter
BCAV_RS14785	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCAV_RS14795	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BCAV_RS14825	COG1819	glycosyl
BCAV_RS14835	COG1079	Belongs to the binding-protein-dependent transport system permease family
BCAV_RS14840	COG4603	Belongs to the binding-protein-dependent transport system permease family
BCAV_RS14845	COG3845	ABC transporter
BCAV_RS14850	COG1744	ABC transporter substrate-binding protein PnrA-like
BCAV_RS14855	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BCAV_RS14855	COG1473	amidohydrolase
BCAV_RS14860	COG0662	Cupin 2, conserved barrel domain protein
BCAV_RS14860	COG0836	Belongs to the mannose-6-phosphate isomerase type 2 family
BCAV_RS14865	COG2009	succinate dehydrogenase
BCAV_RS14880	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BCAV_RS14900	COG0180	Tryptophanyl-tRNA synthetase
BCAV_RS14905	COG1349	DNA-binding transcription factor activity
BCAV_RS14915	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BCAV_RS14930	COG1136	(ABC) transporter
BCAV_RS14930	COG0577	efflux transmembrane transporter activity
BCAV_RS14935	COG1136	(ABC) transporter
BCAV_RS14935	COG0577	efflux transmembrane transporter activity
BCAV_RS14985	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS15000	COG1653	transport
BCAV_RS15005	COG1175	transmembrane transport
BCAV_RS15010	COG0395	ABC-type sugar transport system, permease component
BCAV_RS15015	COG3653	N-Acyl-D-aspartate D-glutamate deacylase
BCAV_RS15020	COG1414	Transcriptional regulator
BCAV_RS15035	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS15040	COG0708	Exodeoxyribonuclease III
BCAV_RS15055	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BCAV_RS15060	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BCAV_RS15070	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCAV_RS15090	COG1940	carbohydrate kinase activity
BCAV_RS15090	COG1846	Transcriptional regulator
BCAV_RS15095	COG4214	carbohydrate transport
BCAV_RS15105	COG4213	ABC transporter substrate-binding protein
BCAV_RS15120	COG0395	ABC-type sugar transport system, permease component
BCAV_RS15125	COG1175	transmembrane transport
BCAV_RS15135	COG1309	transcriptional regulator
BCAV_RS15145	COG0039	L-malate dehydrogenase activity
BCAV_RS15165	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BCAV_RS15200	COG0045	succinate-CoA ligase (ADP-forming) activity
BCAV_RS15250	COG3851	Histidine kinase
BCAV_RS15260	COG4152	abc transporter atp-binding protein
BCAV_RS15275	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BCAV_RS15280	COG2197	response regulator
BCAV_RS15305	COG0519	Catalyzes the synthesis of GMP from XMP
BCAV_RS15305	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BCAV_RS15320	COG1132	(ABC) transporter
BCAV_RS15325	COG1132	(ABC) transporter
BCAV_RS15360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BCAV_RS15370	COG0114	fumarate hydratase activity
BCAV_RS15375	COG0456	acetyltransferase
BCAV_RS15380	COG0516	GMP reductase activity
BCAV_RS15405	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BCAV_RS15420	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
BCAV_RS15450	COG2116	formate transmembrane transporter activity
BCAV_RS15455	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BCAV_RS15465	COG0456	acetyltransferase
BCAV_RS15475	COG0802	atpase or kinase
BCAV_RS15480	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BCAV_RS15505	COG1175	transmembrane transport
BCAV_RS15510	COG3833	ABC-type maltose transport systems, permease component
BCAV_RS15515	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BCAV_RS15535	COG0736	holo-[acyl-carrier-protein] synthase activity
BCAV_RS15545	COG0745	RESPONSE REGULATOR receiver
BCAV_RS15550	COG2205	protein histidine kinase activity
BCAV_RS15555	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BCAV_RS15595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCAV_RS15600	COG3629	intracellular signal transduction
BCAV_RS15600	COG3903	Transcriptional regulator
BCAV_RS15610	COG3629	intracellular signal transduction
BCAV_RS15610	COG3903	Transcriptional regulator
BCAV_RS15615	COG1072	(Pantothenic acid kinase))
BCAV_RS15630	COG0242	peptide deformylase activity
BCAV_RS15635	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BCAV_RS15640	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BCAV_RS15645	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BCAV_RS15660	COG0101	tRNA pseudouridine synthase activity
BCAV_RS15675	COG0203	ribosomal protein L17
BCAV_RS15680	COG0202	RNA polymerase activity
BCAV_RS15685	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BCAV_RS15690	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BCAV_RS15695	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BCAV_RS15705	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BCAV_RS15720	COG0563	adenylate kinase activity
BCAV_RS15730	COG0200	Binds to the 23S rRNA
BCAV_RS15735	COG1841	ribosomal large subunit assembly
BCAV_RS15740	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BCAV_RS15750	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BCAV_RS15755	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BCAV_RS15760	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BCAV_RS15765	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BCAV_RS15770	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BCAV_RS15775	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BCAV_RS15780	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BCAV_RS15785	COG0255	Belongs to the universal ribosomal protein uL29 family
BCAV_RS15790	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BCAV_RS15795	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BCAV_RS15800	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BCAV_RS15805	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BCAV_RS15810	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BCAV_RS15815	COG0089	rRNA binding
BCAV_RS15820	COG0088	Forms part of the polypeptide exit tunnel
BCAV_RS15825	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BCAV_RS15830	COG0051	transcription antitermination factor activity, RNA binding
BCAV_RS15835	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BCAV_RS15840	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BCAV_RS15845	COG0049	tRNA binding
BCAV_RS15850	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BCAV_RS15855	COG2211	Major facilitator Superfamily
BCAV_RS15875	COG4555	ABC transporter
BCAV_RS15880	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BCAV_RS15885	COG0085	RNA polymerase activity
BCAV_RS15890	COG0222	ribosome binding
BCAV_RS15895	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BCAV_RS15910	COG0081	regulation of translation
BCAV_RS15915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BCAV_RS15935	COG0436	Aminotransferase
BCAV_RS15945	COG5000	phosphorelay sensor kinase activity
BCAV_RS15945	COG5002	protein histidine kinase activity
BCAV_RS15970	COG1131	(ABC) transporter
BCAV_RS15980	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BCAV_RS15995	COG4591	ABC-type transport system involved in lipoprotein release permease component
BCAV_RS15995	COG1136	(ABC) transporter
BCAV_RS16005	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BCAV_RS16010	COG0738	Major facilitator superfamily
BCAV_RS16030	COG2030	dehydratase
BCAV_RS16035	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BCAV_RS16050	COG1063	alcohol dehydrogenase
BCAV_RS16055	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BCAV_RS16060	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
BCAV_RS16070	COG1666	GTP binding
BCAV_RS16095	COG0501	Belongs to the peptidase M48B family
BCAV_RS16140	COG1404	Belongs to the peptidase S8 family
BCAV_RS16175	COG1404	Belongs to the peptidase S8 family
BCAV_RS16200	COG1674	ftsk spoiiie
BCAV_RS16205	COG0142	geranyltranstransferase activity
BCAV_RS16210	COG1007	ATP synthesis coupled electron transport
BCAV_RS16220	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCAV_RS16225	COG0713	ATP synthesis coupled electron transport
BCAV_RS16230	COG0839	Belongs to the complex I subunit 6 family
BCAV_RS16235	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCAV_RS16240	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BCAV_RS16245	COG1034	ATP synthesis coupled electron transport
BCAV_RS16250	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BCAV_RS16260	COG0649	NAD binding
BCAV_RS16265	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCAV_RS16270	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BCAV_RS16290	COG2226	methyltransferase
BCAV_RS16295	COG1169	isochorismate synthase
BCAV_RS16300	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCAV_RS16305	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BCAV_RS16310	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS16315	COG1253	flavin adenine dinucleotide binding
BCAV_RS16330	COG2239	Acts as a magnesium transporter
BCAV_RS16345	COG0447	Converts o-succinylbenzoyl-CoA (OSB-CoA) to 1,4- dihydroxy-2-naphthoyl-CoA (DHNA-CoA)
BCAV_RS16380	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BCAV_RS16390	COG0785	Cytochrome C biogenesis protein
BCAV_RS16400	COG0406	alpha-ribazole phosphatase activity
BCAV_RS16425	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BCAV_RS16445	COG1819	glycosyl
BCAV_RS16460	COG0123	including yeast histone deacetylase and acetoin utilization protein
BCAV_RS16465	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BCAV_RS16470	COG0569	domain protein
BCAV_RS16475	COG1063	alcohol dehydrogenase
BCAV_RS16480	COG2160	L-arabinose isomerase activity
BCAV_RS16495	COG1609	Transcriptional regulator
BCAV_RS16500	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BCAV_RS16515	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
BCAV_RS16520	COG1623	Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c- di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation
BCAV_RS16530	COG1194	a g-specific adenine glycosylase
BCAV_RS16555	COG1246	Belongs to the acetyltransferase family. ArgA subfamily
BCAV_RS16565	COG0578	Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family
BCAV_RS16570	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCAV_RS16575	COG0554	Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate
BCAV_RS16580	COG3507	Belongs to the glycosyl hydrolase 43 family
BCAV_RS16605	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BCAV_RS16625	COG0531	amino acid
BCAV_RS16630	COG0395	ABC-type sugar transport system, permease component
BCAV_RS16635	COG1175	transmembrane transport
BCAV_RS16650	COG1070	Carbohydrate kinase
BCAV_RS16655	COG2115	Belongs to the xylose isomerase family
BCAV_RS16680	COG1904	glucuronate isomerase
BCAV_RS16685	COG1609	Transcriptional regulator
BCAV_RS16695	COG0673	inositol 2-dehydrogenase activity
BCAV_RS16705	COG0246	Mannitol dehydrogenase
BCAV_RS16710	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS16715	COG1609	Transcriptional regulator
BCAV_RS16740	COG0395	ABC-type sugar transport system, permease component
BCAV_RS16745	COG4209	transmembrane transport
BCAV_RS16780	COG0477	Major facilitator Superfamily
BCAV_RS16785	COG1309	transcriptional regulator
BCAV_RS16825	COG0601	transmembrane transport
BCAV_RS16830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS16860	COG0673	inositol 2-dehydrogenase activity
BCAV_RS16865	COG0673	inositol 2-dehydrogenase activity
BCAV_RS16875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS16885	COG0363	glucosamine-6-phosphate deaminase activity
BCAV_RS16900	COG1609	Transcriptional regulator
BCAV_RS16940	COG0673	inositol 2-dehydrogenase activity
BCAV_RS16945	COG0673	inositol 2-dehydrogenase activity
BCAV_RS16965	COG1672	PFAM Archaeal ATPase
BCAV_RS16965	COG2114	Pfam Adenylate and Guanylate cyclase catalytic domain
BCAV_RS16980	COG3618	amidohydrolase
BCAV_RS16985	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCAV_RS16995	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BCAV_RS17010	COG3275	phosphorelay sensor kinase activity
BCAV_RS17040	COG1609	Transcriptional regulator
BCAV_RS17050	COG4209	transmembrane transport
BCAV_RS17055	COG0395	ABC-type sugar transport system, permease component
BCAV_RS17065	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
BCAV_RS17080	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS17115	COG1609	Transcriptional regulator
BCAV_RS17125	COG0601	transmembrane transport
BCAV_RS17130	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS17135	COG4172	Belongs to the ABC transporter superfamily
BCAV_RS17150	COG0477	Major facilitator Superfamily
BCAV_RS17160	COG0477	Major facilitator Superfamily
BCAV_RS17165	COG1490	D-aminoacyl-tRNA deacylase activity
BCAV_RS17200	COG3485	protocatechuate 3,4-dioxygenase
BCAV_RS17210	COG0745	RESPONSE REGULATOR receiver
BCAV_RS17220	COG0306	phosphate transporter
BCAV_RS17230	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BCAV_RS17250	COG0406	alpha-ribazole phosphatase activity
BCAV_RS17250	COG0494	nUDIX hydrolase
BCAV_RS17255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BCAV_RS17260	COG0456	acetyltransferase
BCAV_RS17275	COG1595	DNA-templated transcription, initiation
BCAV_RS17295	COG1832	CoA-binding protein
BCAV_RS17305	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BCAV_RS17315	COG1116	anion transmembrane transporter activity
BCAV_RS17355	COG4608	Belongs to the ABC transporter superfamily
BCAV_RS17360	COG0444	Belongs to the ABC transporter superfamily
BCAV_RS17365	COG0747	negative chemotaxis
BCAV_RS17370	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS17380	COG1609	Transcriptional regulator
BCAV_RS17450	COG1302	Protein conserved in bacteria
BCAV_RS17455	COG1595	DNA-templated transcription, initiation
BCAV_RS17470	COG1595	DNA-templated transcription, initiation
BCAV_RS17520	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BCAV_RS17530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BCAV_RS17555	COG0702	epimerase
BCAV_RS17560	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BCAV_RS17585	COG1105	Belongs to the carbohydrate kinase PfkB family
BCAV_RS17590	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BCAV_RS17610	COG0747	negative chemotaxis
BCAV_RS17655	COG0789	Transcriptional regulator
BCAV_RS17660	COG0667	Aldo Keto reductase
BCAV_RS17690	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BCAV_RS17710	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BCAV_RS17720	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BCAV_RS17720	COG1651	Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process
BCAV_RS17745	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BCAV_RS17765	COG0446	pyridine nucleotide-disulphide oxidoreductase
BCAV_RS17770	COG1595	DNA-templated transcription, initiation
BCAV_RS17775	COG1162	GTPase activity
BCAV_RS17790	COG3173	Aminoglycoside phosphotransferase
BCAV_RS17795	COG0477	Major facilitator Superfamily
BCAV_RS17810	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCAV_RS17820	COG1105	Belongs to the carbohydrate kinase PfkB family
BCAV_RS17830	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BCAV_RS17840	COG2197	response regulator
BCAV_RS17845	COG4585	Histidine kinase
BCAV_RS17860	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCAV_RS17880	COG1695	Transcriptional regulator
BCAV_RS17905	COG0395	ABC-type sugar transport system, permease component
BCAV_RS17910	COG1175	transmembrane transport
BCAV_RS17925	COG3622	Belongs to the hyi family
BCAV_RS17935	COG2084	Dehydrogenase
BCAV_RS17950	COG1404	Belongs to the peptidase S8 family
BCAV_RS17960	COG1053	succinate dehydrogenase
BCAV_RS18005	COG0395	ABC-type sugar transport system, permease component
BCAV_RS18015	COG3459	Glycosyltransferase 36 associated
BCAV_RS18030	COG1522	sequence-specific DNA binding
BCAV_RS18035	COG1132	(ABC) transporter
BCAV_RS18040	COG1132	(ABC) transporter
BCAV_RS18055	COG0464	growth
BCAV_RS18060	COG0183	Belongs to the thiolase family
BCAV_RS18065	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS18070	COG2030	dehydratase
BCAV_RS18095	COG0047	phosphoribosylformylglycinamidine synthase activity
BCAV_RS18100	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BCAV_RS18110	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BCAV_RS18130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BCAV_RS18135	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BCAV_RS18140	COG0151	Belongs to the GarS family
BCAV_RS18145	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BCAV_RS18180	COG1609	Transcriptional regulator
BCAV_RS18215	COG1175	transmembrane transport
BCAV_RS18220	COG0395	ABC-type sugar transport system, permease component
BCAV_RS18245	COG3250	beta-galactosidase activity
BCAV_RS18250	COG0395	ABC-type sugar transport system, permease component
BCAV_RS18255	COG1175	transmembrane transport
BCAV_RS18265	COG4952	isomerase
BCAV_RS18270	COG3347	Dehydrogenase
BCAV_RS18270	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS18275	COG1070	Carbohydrate kinase
BCAV_RS18290	COG0667	Aldo Keto reductase
BCAV_RS18305	COG0842	Transport permease protein
BCAV_RS18305	COG1129	ABC transporter
BCAV_RS18325	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BCAV_RS18350	COG0191	fructose-bisphosphate aldolase activity
BCAV_RS18375	COG1704	LemA family
BCAV_RS18380	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BCAV_RS18405	COG0702	epimerase
BCAV_RS18410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BCAV_RS18445	COG0601	transmembrane transport
BCAV_RS18450	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BCAV_RS18465	COG1063	alcohol dehydrogenase
BCAV_RS18470	COG0588	phosphoglycerate mutase activity
BCAV_RS18485	COG1595	DNA-templated transcription, initiation
BCAV_RS18490	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BCAV_RS18495	COG0154	amidase activity
BCAV_RS18515	COG0445	tRNA wobble uridine modification
BCAV_RS18525	COG1175	transmembrane transport
BCAV_RS18530	COG0395	ABC-type sugar transport system, permease component
BCAV_RS18590	COG1132	(ABC) transporter
BCAV_RS18620	COG1505	serine-type exopeptidase activity
BCAV_RS18630	COG1064	alcohol dehydrogenase
BCAV_RS18640	COG0740	serine-type endopeptidase activity
BCAV_RS18645	COG0740	serine-type endopeptidase activity
BCAV_RS18665	COG0640	Transcriptional regulator
BCAV_RS18670	COG1331	Highly conserved protein containing a thioredoxin domain
BCAV_RS18675	COG0789	Transcriptional regulator
BCAV_RS18680	COG0484	heat shock protein binding
BCAV_RS18685	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BCAV_RS18690	COG0443	Heat shock 70 kDa protein
BCAV_RS18700	COG1414	Transcriptional regulator
BCAV_RS18710	COG1175	transmembrane transport
BCAV_RS18715	COG0395	ABC-type sugar transport system, permease component
BCAV_RS18725	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BCAV_RS18725	COG0473	3-isopropylmalate dehydrogenase activity
BCAV_RS18735	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS18740	COG1312	Catalyzes the dehydration of D-mannonate
BCAV_RS18755	COG2226	methyltransferase
BCAV_RS18770	COG1132	(ABC) transporter
BCAV_RS18790	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BCAV_RS18850	COG1357	PFAM Pentapeptide repeats (8 copies)
BCAV_RS18860	COG1733	regulation of RNA biosynthetic process
BCAV_RS18875	COG3570	aminoglycoside hydroxyurea antibiotic resistance kinase
BCAV_RS18880	COG0372	Belongs to the citrate synthase family
BCAV_RS18895	COG0346	lactoylglutathione lyase activity
BCAV_RS18915	COG3559	Exporter of polyketide antibiotics
BCAV_RS18920	COG1131	(ABC) transporter
BCAV_RS18925	COG1309	transcriptional regulator
BCAV_RS18930	COG0494	nUDIX hydrolase
BCAV_RS18955	COG4941	Belongs to the sigma-70 factor family
BCAV_RS18980	COG2188	Transcriptional regulator
BCAV_RS18985	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BCAV_RS18995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS19000	COG0673	inositol 2-dehydrogenase activity
BCAV_RS19010	COG1175	transmembrane transport
BCAV_RS19015	COG1653	transport
BCAV_RS19020	COG2186	Transcriptional regulator
BCAV_RS19040	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BCAV_RS19050	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BCAV_RS19090	COG0395	ABC-type sugar transport system, permease component
BCAV_RS19095	COG1175	transmembrane transport
BCAV_RS19115	COG5564	TIM-barrel signal transduction protein
BCAV_RS19125	COG1846	Transcriptional regulator
BCAV_RS19125	COG1940	carbohydrate kinase activity
BCAV_RS19145	COG1131	(ABC) transporter
BCAV_RS19150	COG4585	Histidine kinase
BCAV_RS19155	COG2197	response regulator
BCAV_RS19170	COG3842	ATPase activity
BCAV_RS19180	COG4143	(ABC) transporter
BCAV_RS19200	COG1320	monovalent cation:proton antiporter activity
BCAV_RS19205	COG2212	antiporter activity
BCAV_RS19215	COG0651	ATP synthesis coupled electron transport
BCAV_RS19220	COG1006	Multisubunit Na H antiporter MnhC subunit
BCAV_RS19225	COG2111	Na H antiporter
BCAV_RS19225	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BCAV_RS19250	COG0717	Belongs to the dCTP deaminase family
BCAV_RS19330	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS19360	COG1316	TRANSCRIPTIONal
BCAV_RS19365	COG0183	Belongs to the thiolase family
BCAV_RS19390	COG1960	acyl-CoA dehydrogenase activity
BCAV_RS19400	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BCAV_RS19405	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCAV_RS19410	COG0022	dehydrogenase e1 component
BCAV_RS19485	COG0477	Major facilitator Superfamily
BCAV_RS19500	COG5398	heme oxygenase
BCAV_RS19525	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BCAV_RS19530	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BCAV_RS19535	COG4558	Periplasmic binding protein
BCAV_RS19565	COG1404	Belongs to the peptidase S8 family
BCAV_RS19580	COG1131	(ABC) transporter
BCAV_RS19590	COG4585	Histidine kinase
BCAV_RS19595	COG2197	response regulator
BCAV_RS19630	COG0395	ABC-type sugar transport system, permease component
BCAV_RS19635	COG1175	transmembrane transport
BCAV_RS19645	COG3119	arylsulfatase activity
BCAV_RS19665	COG2378	regulation of single-species biofilm formation
BCAV_RS19675	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BCAV_RS19720	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BCAV_RS19750	COG0673	inositol 2-dehydrogenase activity
BCAV_RS19760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCAV_RS19765	COG2364	Membrane
BCAV_RS19770	COG0442	prolyl-tRNA aminoacylation
BCAV_RS19780	COG0640	Transcriptional regulator
BCAV_RS19840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS19850	COG1175	transmembrane transport
BCAV_RS19855	COG0395	ABC-type sugar transport system, permease component
BCAV_RS19860	COG3386	PFAM SMP-30 Gluconolaconase
BCAV_RS19865	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS19875	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS19885	COG4946	Tricorn protease homolog
BCAV_RS19885	COG1506	peptidase
BCAV_RS19885	COG0823	Involved in the tonB-independent uptake of proteins
BCAV_RS19895	COG1505	serine-type exopeptidase activity
BCAV_RS19915	COG3336	cytochrome c oxidase
BCAV_RS19925	COG0714	Associated with various cellular activities
BCAV_RS19965	COG0508	dehydrogenase complex catalyzes the overall conversion of
BCAV_RS19970	COG0022	dehydrogenase e1 component
BCAV_RS19985	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BCAV_RS19990	COG1950	PFAM Membrane protein of
BCAV_RS20020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BCAV_RS20040	COG3119	arylsulfatase activity
BCAV_RS20060	COG0395	ABC-type sugar transport system, permease component
BCAV_RS20070	COG3540	Alkaline phosphatase
BCAV_RS20085	COG0395	ABC-type sugar transport system, permease component
BCAV_RS20090	COG1175	transmembrane transport
BCAV_RS20110	COG0395	ABC-type sugar transport system, permease component
BCAV_RS20115	COG1175	transmembrane transport
BCAV_RS20120	COG1653	transport
BCAV_RS20125	COG4821	SIS domain
BCAV_RS20135	COG2971	BadF BadG BcrA BcrD
BCAV_RS20145	COG2197	response regulator
BCAV_RS20150	COG4585	Histidine kinase
BCAV_RS20160	COG2132	Multicopper oxidase
BCAV_RS20165	COG1309	transcriptional regulator
BCAV_RS20180	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
BCAV_RS20185	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BCAV_RS20195	COG0181	hydroxymethylbilane synthase activity
BCAV_RS20205	COG0113	porphobilinogen synthase activity
BCAV_RS20210	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
BCAV_RS20245	COG1937	Protein conserved in bacteria
BCAV_RS20265	COG1131	(ABC) transporter
BCAV_RS20315	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS20320	COG2272	Belongs to the type-B carboxylesterase lipase family
BCAV_RS20330	COG1680	COG1680 Beta-lactamase class C and other penicillin binding
BCAV_RS20335	COG2320	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A
BCAV_RS20345	COG4209	transmembrane transport
BCAV_RS20350	COG0395	ABC-type sugar transport system, permease component
BCAV_RS20375	COG0584	glycerophosphoryl diester phosphodiesterase
BCAV_RS20390	COG3142	Participates in the control of copper homeostasis
BCAV_RS20410	COG2169	Transcriptional regulator
BCAV_RS20410	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BCAV_RS20425	COG0395	ABC-type sugar transport system, permease component
BCAV_RS20430	COG1175	transmembrane transport
BCAV_RS20440	COG0673	inositol 2-dehydrogenase activity
BCAV_RS20445	COG1349	DNA-binding transcription factor activity
BCAV_RS20455	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCAV_RS20465	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
BCAV_RS20485	COG1848	Toxic component of a toxin-antitoxin (TA) module. An RNase
BCAV_RS20490	COG4948	Mandelate Racemase Muconate Lactonizing
BCAV_RS20505	COG0667	Aldo Keto reductase
BCAV_RS20515	COG4941	Belongs to the sigma-70 factor family
BCAV_RS20520	COG3795	YCII-related domain
BCAV_RS20555	COG4106	trans-aconitate 2-methyltransferase activity
BCAV_RS20565	COG4941	Belongs to the sigma-70 factor family
BCAV_RS20590	COG0495	leucyl-tRNA aminoacylation
BCAV_RS20595	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BCAV_RS20600	COG0633	Ferredoxin
BCAV_RS20600	COG0543	2 iron, 2 sulfur cluster binding
BCAV_RS20610	COG0697	spore germination
BCAV_RS20645	COG2814	Major facilitator Superfamily
BCAV_RS20695	COG4941	Belongs to the sigma-70 factor family
BCAV_RS20730	COG0667	Aldo Keto reductase
BCAV_RS20775	COG4941	Belongs to the sigma-70 factor family
BCAV_RS20820	COG2318	DinB family
BCAV_RS20830	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCAV_RS20855	COG0322	excinuclease ABC activity
BCAV_RS20880	COG1595	DNA-templated transcription, initiation
BCAV_RS20905	COG3973	AAA domain
BCAV_RS20910	COG2357	RelA SpoT domain protein
BCAV_RS20925	COG2197	response regulator
BCAV_RS20935	COG1136	(ABC) transporter
BCAV_RS20960	COG0640	Transcriptional regulator
BCAV_RS20980	COG3285	dna ligase
BCAV_RS20980	COG1793	dna ligase
BCAV_RS20990	COG0017	Asparaginyl-tRNA synthetase
BCAV_RS21005	COG4221	oxidoreductase activity
BCAV_RS21010	COG0305	Participates in initiation and elongation during chromosome replication
BCAV_RS21015	COG0534	Mate efflux family protein
BCAV_RS21025	COG0359	binds to the 23S rRNA
BCAV_RS21030	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BCAV_RS21040	COG0360	Binds together with S18 to 16S ribosomal RNA
BCAV_RS21045	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BCAV_RS21060	COG0673	inositol 2-dehydrogenase activity
BCAV_RS21070	COG1063	alcohol dehydrogenase
BCAV_RS21080	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BCAV_RS21085	COG2188	Transcriptional regulator
BCAV_RS21090	COG0673	inositol 2-dehydrogenase activity
BCAV_RS21095	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BCAV_RS21100	COG1028	Short-chain dehydrogenase reductase Sdr
BCAV_RS21115	COG0395	ABC-type sugar transport system, permease component
BCAV_RS21120	COG1175	transmembrane transport
BCAV_RS21140	COG1260	myo-inositol-1-phosphate synthase
BCAV_RS21145	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BCAV_RS21170	COG0617	tRNA 3'-terminal CCA addition
BCAV_RS21185	COG0728	peptidoglycan biosynthetic process
BCAV_RS21205	COG0492	ferredoxin-NADP+ reductase activity
BCAV_RS21210	COG3118	belongs to the thioredoxin family
BCAV_RS21215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BCAV_RS21220	COG1181	Belongs to the D-alanine--D-alanine ligase family
BCAV_RS21235	COG1192	Involved in chromosome partitioning
BCAV_RS21240	COG0357	Ribosomal RNA small subunit methyltransferase G
BCAV_RS21250	COG0706	membrane insertase activity
BCAV_RS21260	COG0594	ribonuclease P activity
BCAV_RS21265	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BCAV_RS21290	COG1403	HNH endonuclease
BCAV_RS21365	COG1404	Belongs to the peptidase S8 family
BCAV_RS21365	COG4412	M6 family metalloprotease domain protein
BCAV_RS21425	COG1309	transcriptional regulator
BCAV_RS21430	COG2207	Transcriptional regulator
BCAV_RS21430	COG1917	Cupin 2, conserved barrel domain protein
BCAV_RS21440	COG2133	pyrroloquinoline quinone binding
BCAV_RS21440	COG5183	chlorophyll binding
BCAV_RS21475	COG3708	Transcriptional regulator
BCAV_RS21475	COG2207	Transcriptional regulator
BCAV_RS21485	COG2247	cell wall binding repeat
BCAV_RS21485	COG2385	sporulation resulting in formation of a cellular spore
BCAV_RS21490	COG0438	transferase activity, transferring glycosyl groups
BCAV_RS21525	COG1196	nuclear chromosome segregation
BCAV_RS21525	COG0739	heme binding
BCAV_RS21525	COG0741	lytic transglycosylase activity
BCAV_RS21560	COG3311	Transcriptional regulator
BCAV_RS21595	COG4585	Histidine kinase
BCAV_RS21615	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BCAV_RS21620	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BCAV_RS21645	COG0598	Magnesium transport protein CorA
BCAV_RS21680	COG4585	Histidine kinase
BCAV_RS21725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BCAV_RS21730	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BCAV_RS21730	COG2755	lipolytic protein G-D-S-L family
BCAV_RS21755	COG4166	transmembrane transport
BCAV_RS21770	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BCAV_RS21810	COG1525	nuclease
BCAV_RS21825	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BCAV_RS21855	COG0259	pyridoxamine-phosphate oxidase activity
BCAV_RS21905	COG0590	tRNA wobble adenosine to inosine editing
BCAV_RS21905	COG0037	tRNA processing
BCAV_RS21940	COG0596	Alpha beta hydrolase
BCAV_RS21945	COG0759	Could be involved in insertion of integral membrane proteins into the membrane