locus-tag	class	description
BAD_RS00010	COG0592	DNA-directed DNA polymerase activity
BAD_RS00025	COG0187	DNA topoisomerase II activity
BAD_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BAD_RS00040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BAD_RS00045	COG1970	mechanosensitive ion channel activity
BAD_RS00070	COG1253	flavin adenine dinucleotide binding
BAD_RS00110	COG3409	Peptidoglycan-binding domain 1 protein
BAD_RS00130	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BAD_RS00140	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BAD_RS00145	COG0180	Tryptophanyl-tRNA synthetase
BAD_RS00160	COG0058	SHG alpha-glucan phosphorylase activity
BAD_RS00190	COG3764	Sortase (surface protein transpeptidase)
BAD_RS00205	COG0515	serine threonine protein kinase
BAD_RS00210	COG0768	penicillin binding
BAD_RS00245	COG2197	response regulator
BAD_RS00260	COG0071	Belongs to the small heat shock protein (HSP20) family
BAD_RS00285	COG2197	response regulator
BAD_RS00290	COG0343	queuine tRNA-ribosyltransferase activity
BAD_RS00305	COG0252	asparaginase activity
BAD_RS00345	COG0191	fructose-bisphosphate aldolase activity
BAD_RS00410	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BAD_RS00425	COG0477	Major facilitator Superfamily
BAD_RS00445	COG1113	amino acid transport
BAD_RS00455	COG0475	glutathione-regulated potassium exporter activity
BAD_RS00455	COG0569	domain protein
BAD_RS00465	COG1113	amino acid transport
BAD_RS00490	COG1846	Transcriptional regulator
BAD_RS00500	COG1132	(ABC) transporter
BAD_RS00505	COG4989	oxidoreductase activity
BAD_RS00515	COG0672	)-iron permease
BAD_RS00520	COG3470	protein probably involved in high-affinity Fe2 transport
BAD_RS00585	COG1215	transferase activity, transferring glycosyl groups
BAD_RS00590	COG1309	transcriptional regulator
BAD_RS00620	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BAD_RS00625	COG0305	Participates in initiation and elongation during chromosome replication
BAD_RS00630	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BAD_RS00635	COG3442	glutamine amidotransferase
BAD_RS00660	COG0584	glycerophosphoryl diester phosphodiesterase
BAD_RS00675	COG0494	nUDIX hydrolase
BAD_RS00675	COG0406	alpha-ribazole phosphatase activity
BAD_RS00680	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BAD_RS00795	COG1609	Transcriptional regulator
BAD_RS00800	COG3940	Belongs to the glycosyl hydrolase 43 family
BAD_RS00810	COG1175	transmembrane transport
BAD_RS00815	COG0395	ABC-type sugar transport system, permease component
BAD_RS00830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BAD_RS00835	COG1260	myo-inositol-1-phosphate synthase
BAD_RS00850	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BAD_RS00850	COG1754	DNA topoisomerase type I activity
BAD_RS00860	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BAD_RS00865	COG1609	Transcriptional regulator
BAD_RS00875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BAD_RS00965	COG0167	dihydroorotate dehydrogenase activity
BAD_RS00970	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BAD_RS01005	COG3842	ATPase activity
BAD_RS01030	COG1309	transcriptional regulator
BAD_RS01035	COG0436	Aminotransferase
BAD_RS01040	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BAD_RS01050	COG3265	gluconokinase activity
BAD_RS01065	COG2270	Major facilitator Superfamily
BAD_RS01080	COG0742	ribosomal rna small subunit methyltransferase
BAD_RS01095	COG1837	Belongs to the UPF0109 family
BAD_RS01120	COG0505	Belongs to the CarA family
BAD_RS01125	COG0488	(ABC) transporter
BAD_RS01250	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BAD_RS01255	COG1136	(ABC) transporter
BAD_RS01270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BAD_RS01275	COG1530	ribonuclease E activity
BAD_RS01300	COG0436	Aminotransferase
BAD_RS01310	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BAD_RS01315	COG0250	Participates in transcription elongation, termination and antitermination
BAD_RS01345	COG1268	BioY protein
BAD_RS01350	COG4770	biotin carboxylase activity
BAD_RS01355	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BAD_RS01390	COG1704	LemA family
BAD_RS01415	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BAD_RS01420	COG0826	peptidase U32
BAD_RS01435	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BAD_RS01445	COG3579	cysteine-type endopeptidase activity
BAD_RS01450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BAD_RS01455	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BAD_RS01460	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BAD_RS01465	COG5002	protein histidine kinase activity
BAD_RS01470	COG0745	RESPONSE REGULATOR receiver
BAD_RS01500	COG2252	PERMEase
BAD_RS01540	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BAD_RS01580	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BAD_RS01585	COG0531	amino acid
BAD_RS01615	COG3507	Belongs to the glycosyl hydrolase 43 family
BAD_RS01630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BAD_RS01640	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BAD_RS01645	COG1739	Uncharacterized protein family UPF0029
BAD_RS01695	COG1063	alcohol dehydrogenase
BAD_RS01705	COG1012	belongs to the aldehyde dehydrogenase family
BAD_RS01705	COG1454	alcohol dehydrogenase
BAD_RS01755	COG0255	Belongs to the universal ribosomal protein uL29 family
BAD_RS01860	COG2308	Evidence 4 Homologs of previously reported genes of
BAD_RS01900	COG0196	riboflavin kinase activity
BAD_RS01920	COG0328	RNA-DNA hybrid ribonuclease activity
BAD_RS01925	COG3290	protein histidine kinase activity
BAD_RS01945	COG3711	transcriptional antiterminator
BAD_RS01950	COG1803	Methylglyoxal synthase
BAD_RS01950	COG1597	lipid kinase activity
BAD_RS01990	COG2814	Major facilitator Superfamily
BAD_RS02000	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BAD_RS02005	COG1575	Belongs to the MenA family. Type 1 subfamily
BAD_RS02015	COG4716	Myosin-crossreactive antigen
BAD_RS02020	COG0704	Plays a role in the regulation of phosphate uptake
BAD_RS02025	COG5002	protein histidine kinase activity
BAD_RS02035	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BAD_RS02040	COG3942	CHAP domain
BAD_RS02040	COG1705	Flagellar rod assembly protein muramidase FlgJ
BAD_RS02045	COG0791	NLP P60 protein
BAD_RS02050	COG0589	response to stress
BAD_RS02080	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BAD_RS02145	COG5001	Diguanylate cyclase
BAD_RS02145	COG1716	ATPase activity
BAD_RS02150	COG1454	alcohol dehydrogenase
BAD_RS02155	COG1216	Glycosyl transferase, family 2
BAD_RS02175	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BAD_RS02180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BAD_RS02195	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BAD_RS02205	COG1946	Acyl-CoA thioesterase
BAD_RS02215	COG0242	peptide deformylase activity
BAD_RS02235	COG2873	o-acetylhomoserine
BAD_RS02245	COG3507	Belongs to the glycosyl hydrolase 43 family
BAD_RS02250	COG1609	Transcriptional regulator
BAD_RS02260	COG1175	transmembrane transport
BAD_RS02265	COG0395	ABC-type sugar transport system, permease component
BAD_RS02270	COG3507	Belongs to the glycosyl hydrolase 43 family
BAD_RS02290	COG1070	Carbohydrate kinase
BAD_RS02295	COG1940	carbohydrate kinase activity
BAD_RS02325	COG3459	Glycosyltransferase 36 associated
BAD_RS02330	COG3459	Glycosyltransferase 36 associated
BAD_RS02380	COG0009	L-threonylcarbamoyladenylate synthase
BAD_RS02385	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BAD_RS02395	COG1609	Transcriptional regulator
BAD_RS02400	COG0366	Alpha amylase catalytic
BAD_RS02415	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BAD_RS02435	COG3590	peptidase
BAD_RS02440	COG0024	Methionine aminopeptidase
BAD_RS02460	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BAD_RS02465	COG2884	Cell division ATP-binding protein ftsE
BAD_RS02470	COG2177	Part of the ABC transporter FtsEX involved in
BAD_RS02475	COG3942	CHAP domain
BAD_RS02475	COG1388	LysM domain
BAD_RS02510	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BAD_RS02535	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BAD_RS02540	COG0747	negative chemotaxis
BAD_RS02550	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAD_RS02560	COG4608	Belongs to the ABC transporter superfamily
BAD_RS02575	COG1136	(ABC) transporter
BAD_RS02585	COG2186	Transcriptional regulator
BAD_RS02590	COG1131	(ABC) transporter
BAD_RS02610	COG0514	ATP-dependent DNA helicase (RecQ)
BAD_RS02625	COG0531	amino acid
BAD_RS02630	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BAD_RS02640	COG0358	DNA primase activity
BAD_RS02685	COG0765	amino acid transport
BAD_RS02690	COG0765	amino acid transport
BAD_RS02695	COG1126	abc transporter atp-binding protein
BAD_RS02700	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAD_RS02720	COG4181	ATPase activity
BAD_RS02730	COG0577	efflux transmembrane transporter activity
BAD_RS02735	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BAD_RS02740	COG0604	alcohol dehydrogenase
BAD_RS02745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BAD_RS02750	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BAD_RS02760	COG1368	sulfuric ester hydrolase activity
BAD_RS02780	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BAD_RS02790	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BAD_RS02820	COG0385	Bile acid
BAD_RS02865	COG0284	orotidine-5'-phosphate decarboxylase activity
BAD_RS02890	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BAD_RS02895	COG1011	Hydrolase
BAD_RS02905	COG0560	Phosphoserine phosphatase
BAD_RS02915	COG4122	O-methyltransferase activity
BAD_RS02955	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BAD_RS02995	COG0714	Associated with various cellular activities
BAD_RS03025	COG0745	RESPONSE REGULATOR receiver
BAD_RS03030	COG2205	protein histidine kinase activity
BAD_RS03035	COG1278	Cold shock
BAD_RS03045	COG0589	response to stress
BAD_RS03055	COG1196	nuclear chromosome segregation
BAD_RS03070	COG0765	amino acid transport
BAD_RS03080	COG1126	abc transporter atp-binding protein
BAD_RS03085	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAD_RS03090	COG0765	amino acid transport
BAD_RS03095	COG0765	amino acid transport
BAD_RS03100	COG2326	polyphosphate kinase activity
BAD_RS03115	COG2814	Major facilitator Superfamily
BAD_RS03155	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BAD_RS03160	COG1053	succinate dehydrogenase
BAD_RS03165	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BAD_RS03165	COG0758	DNA mediated transformation
BAD_RS03185	COG2873	o-acetylhomoserine
BAD_RS03195	COG1122	ATPase activity
BAD_RS03200	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BAD_RS03210	COG1136	(ABC) transporter
BAD_RS03215	COG1136	(ABC) transporter
BAD_RS03215	COG0577	efflux transmembrane transporter activity
BAD_RS03220	COG2197	response regulator
BAD_RS03225	COG4585	Histidine kinase
BAD_RS03235	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BAD_RS03240	COG0012	GTP binding
BAD_RS03250	COG1918	ferrous iron import across plasma membrane
BAD_RS03250	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BAD_RS03295	COG2207	Transcriptional regulator
BAD_RS03295	COG1917	Cupin 2, conserved barrel domain protein
BAD_RS03305	COG2233	PERMEase
BAD_RS03310	COG4221	oxidoreductase activity
BAD_RS03320	COG0390	transport system, permease component
BAD_RS03325	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BAD_RS03335	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BAD_RS03340	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BAD_RS03345	COG0363	glucosamine-6-phosphate deaminase activity
BAD_RS03365	COG0300	oxidoreductase activity
BAD_RS03380	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BAD_RS03390	COG2249	NAD(P)H dehydrogenase (quinone) activity
BAD_RS03395	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BAD_RS03400	COG1687	branched-chain amino acid
BAD_RS03460	COG1760	l-serine dehydratase
BAD_RS03470	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BAD_RS03495	COG1316	TRANSCRIPTIONal
BAD_RS03505	COG1316	TRANSCRIPTIONal
BAD_RS03540	COG2205	protein histidine kinase activity
BAD_RS03545	COG0745	RESPONSE REGULATOR receiver
BAD_RS03570	COG1121	(ABC) transporter
BAD_RS03575	COG0803	Belongs to the bacterial solute-binding protein 9 family
BAD_RS03585	COG0539	negative regulation of cytoplasmic translation
BAD_RS03605	COG0469	pyruvate kinase activity
BAD_RS03625	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BAD_RS03630	COG1051	belongs to the nudix hydrolase family
BAD_RS03670	COG0857	belongs to the CobB CobQ family
BAD_RS03670	COG0280	phosphate acetyltransferase
BAD_RS03675	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BAD_RS03765	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BAD_RS03775	COG1523	belongs to the glycosyl hydrolase 13 family
BAD_RS03790	COG0719	Fe-S assembly protein
BAD_RS03795	COG0396	ATPase activity
BAD_RS03805	COG0822	iron-sulfur transferase activity
BAD_RS03810	COG2151	metal-sulfur cluster biosynthetic enzyme
BAD_RS03830	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BAD_RS03835	COG0537	adenosine 5'-monophosphoramidase activity
BAD_RS03865	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BAD_RS03885	COG0534	Mate efflux family protein
BAD_RS03895	COG0667	Aldo Keto reductase
BAD_RS03910	COG2814	Major facilitator Superfamily
BAD_RS03935	COG1129	ABC transporter
BAD_RS03945	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BAD_RS03965	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BAD_RS03970	COG2860	membrane
BAD_RS03990	COG0070	glutamate synthase
BAD_RS03990	COG0067	glutamate synthase
BAD_RS03990	COG0069	glutamate synthase activity
BAD_RS04005	COG0297	glycogen (starch) synthase activity
BAD_RS04010	COG1119	ATPase activity
BAD_RS04035	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BAD_RS04055	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BAD_RS04060	COG0284	orotidine-5'-phosphate decarboxylase activity
BAD_RS04065	COG0543	2 iron, 2 sulfur cluster binding
BAD_RS04070	COG0167	dihydroorotate dehydrogenase activity
BAD_RS04090	COG1136	(ABC) transporter
BAD_RS04090	COG4591	ABC-type transport system involved in lipoprotein release permease component
BAD_RS04100	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BAD_RS04100	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BAD_RS04105	COG0577	efflux transmembrane transporter activity
BAD_RS04105	COG1136	(ABC) transporter
BAD_RS04130	COG1022	Amp-dependent synthetase and ligase
BAD_RS04145	COG0516	GMP reductase activity
BAD_RS04210	COG0133	tryptophan synthase activity
BAD_RS04225	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BAD_RS04265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BAD_RS04300	COG0045	succinate-CoA ligase (ADP-forming) activity
BAD_RS04385	COG1716	ATPase activity
BAD_RS04445	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BAD_RS04450	COG0436	Aminotransferase
BAD_RS04455	COG0561	phosphatase activity
BAD_RS04460	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BAD_RS04485	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BAD_RS04555	COG0488	(ABC) transporter
BAD_RS04565	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BAD_RS04605	COG0802	atpase or kinase
BAD_RS04615	COG2333	competence protein COMEC
BAD_RS04615	COG0658	competence protein
BAD_RS04620	COG1555	photosystem II stabilization
BAD_RS04620	COG1596	polysaccharide export
BAD_RS04630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAD_RS04635	COG0598	Magnesium transport protein CorA
BAD_RS04640	COG0406	alpha-ribazole phosphatase activity
BAD_RS04655	COG0406	alpha-ribazole phosphatase activity
BAD_RS04660	COG0799	negative regulation of ribosome biogenesis
BAD_RS04675	COG0667	Aldo Keto reductase
BAD_RS04775	COG0577	efflux transmembrane transporter activity
BAD_RS04805	COG0640	Transcriptional regulator
BAD_RS04820	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BAD_RS04855	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BAD_RS04860	COG0497	DNA recombination
BAD_RS04870	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BAD_RS04875	COG0569	domain protein
BAD_RS04970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BAD_RS04980	COG1136	(ABC) transporter
BAD_RS05020	COG0582	viral genome integration into host DNA
BAD_RS05025	COG1396	sequence-specific DNA binding
BAD_RS05030	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BAD_RS05060	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BAD_RS05070	COG1122	ATPase activity
BAD_RS05075	COG4721	ABC-type cobalt transport system, permease component
BAD_RS05105	COG1122	ATPase activity
BAD_RS05125	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BAD_RS05160	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BAD_RS05165	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BAD_RS05180	COG1609	Transcriptional regulator
BAD_RS05185	COG0366	Alpha amylase catalytic
BAD_RS05205	COG3041	Addiction module toxin RelE StbE family
BAD_RS05295	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BAD_RS05300	COG1882	Formate acetyltransferase
BAD_RS05315	COG1473	amidohydrolase
BAD_RS05325	COG1464	Belongs to the NlpA lipoprotein family
BAD_RS05335	COG2011	ABC-type metal ion transport system permease component
BAD_RS05350	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BAD_RS05375	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BAD_RS05380	COG1201	RNA secondary structure unwinding
BAD_RS05390	COG0187	DNA topoisomerase II activity
BAD_RS05395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BAD_RS05405	COG0142	geranyltranstransferase activity
BAD_RS05425	COG2801	Transposase and inactivated derivatives
BAD_RS05435	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BAD_RS05445	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BAD_RS05450	COG2137	regulation of response to DNA damage stimulus
BAD_RS05460	COG1396	sequence-specific DNA binding
BAD_RS05465	COG1546	Belongs to the CinA family
BAD_RS05465	COG1058	Belongs to the CinA family
BAD_RS05470	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BAD_RS05495	COG2357	RelA SpoT domain protein
BAD_RS05505	COG0670	Belongs to the BI1 family
BAD_RS05520	COG2197	response regulator
BAD_RS05530	COG2197	response regulator
BAD_RS05535	COG4585	Histidine kinase
BAD_RS05540	COG1131	(ABC) transporter
BAD_RS05565	COG0110	maltose O-acetyltransferase activity
BAD_RS05570	COG0745	RESPONSE REGULATOR receiver
BAD_RS05570	COG2205	protein histidine kinase activity
BAD_RS05570	COG3292	Two component regulator propeller
BAD_RS05625	COG0708	Exodeoxyribonuclease III
BAD_RS05635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BAD_RS05640	COG0601	transmembrane transport
BAD_RS05645	COG4166	transmembrane transport
BAD_RS05655	COG1136	(ABC) transporter
BAD_RS05655	COG0577	efflux transmembrane transporter activity
BAD_RS05660	COG0577	efflux transmembrane transporter activity
BAD_RS05670	COG0287	Prephenate dehydrogenase
BAD_RS05685	COG1217	gtp-binding protein TYPA
BAD_RS05690	COG0477	Major facilitator Superfamily
BAD_RS05720	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BAD_RS05725	COG0367	asparagine synthase
BAD_RS05740	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BAD_RS05750	COG2017	converts alpha-aldose to the beta-anomer
BAD_RS05760	COG1595	DNA-templated transcription, initiation
BAD_RS05775	COG1794	racemase activity, acting on amino acids and derivatives
BAD_RS05780	COG0285	dihydrofolate synthase activity
BAD_RS05785	COG0006	proline dipeptidase activity
BAD_RS05805	COG0601	transmembrane transport
BAD_RS05815	COG1940	carbohydrate kinase activity
BAD_RS05860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BAD_RS05870	COG0768	penicillin binding
BAD_RS05895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BAD_RS05925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BAD_RS05930	COG2813	Specifically methylates the guanine in position
BAD_RS05935	COG1643	Atp-dependent helicase
BAD_RS05940	COG2814	Major facilitator Superfamily
BAD_RS05950	COG0174	glutamine synthetase
BAD_RS05985	COG0587	DNA-directed DNA polymerase activity
BAD_RS06015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BAD_RS06070	COG0351	phosphomethylpyrimidine kinase
BAD_RS06070	COG0352	thiamine-phosphate diphosphorylase activity
BAD_RS06095	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BAD_RS06150	COG3480	Lon protease (S16) C-terminal proteolytic domain
BAD_RS06175	COG0613	PHP domain protein
BAD_RS06185	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BAD_RS06210	COG0747	negative chemotaxis
BAD_RS06230	COG2801	Transposase and inactivated derivatives
BAD_RS06240	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BAD_RS06245	COG1518	maintenance of DNA repeat elements
BAD_RS06285	COG1609	Transcriptional regulator
BAD_RS06295	COG1132	(ABC) transporter
BAD_RS06300	COG1132	(ABC) transporter
BAD_RS06320	COG1929	Belongs to the glycerate kinase type-1 family
BAD_RS06350	COG1309	transcriptional regulator
BAD_RS06360	COG3507	Belongs to the glycosyl hydrolase 43 family
BAD_RS06405	COG1309	transcriptional regulator
BAD_RS06425	COG1328	CTP reductase activity
BAD_RS06425	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BAD_RS06430	COG1570	exodeoxyribonuclease VII activity
BAD_RS06435	COG1722	exodeoxyribonuclease VII activity
BAD_RS06460	COG1192	Involved in chromosome partitioning
BAD_RS06475	COG0248	Ppx GppA phosphatase
BAD_RS06480	COG0436	Aminotransferase
BAD_RS06495	COG0210	DNA helicase
BAD_RS06680	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BAD_RS06685	COG0765	amino acid transport
BAD_RS06700	COG1126	abc transporter atp-binding protein
BAD_RS06760	COG1192	Involved in chromosome partitioning
BAD_RS06790	COG1401	restriction endodeoxyribonuclease activity
BAD_RS06810	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BAD_RS06820	COG2723	6-phospho-beta-galactosidase activity
BAD_RS06830	COG1175	transmembrane transport
BAD_RS06880	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BAD_RS06890	COG2807	transmembrane transport
BAD_RS06900	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BAD_RS06910	COG1937	Protein conserved in bacteria
BAD_RS06945	COG2815	serine threonine protein kinase
BAD_RS06945	COG0515	serine threonine protein kinase
BAD_RS06955	COG0714	Associated with various cellular activities
BAD_RS06970	COG0631	protein serine/threonine phosphatase activity
BAD_RS07005	COG1194	a g-specific adenine glycosylase
BAD_RS07010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BAD_RS07025	COG1621	beta-fructofuranosidase activity
BAD_RS07040	COG0395	ABC-type sugar transport system, permease component
BAD_RS07045	COG4209	transmembrane transport
BAD_RS07055	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BAD_RS07065	COG1349	DNA-binding transcription factor activity
BAD_RS07070	COG0167	dihydroorotate dehydrogenase activity
BAD_RS07075	COG1902	pentaerythritol trinitrate reductase activity
BAD_RS07080	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BAD_RS07080	COG4499	WXG100 protein secretion system (Wss), protein YukC
BAD_RS07090	COG0095	Lipoate-protein ligase
BAD_RS07125	COG1376	ErfK ybiS ycfS ynhG family protein
BAD_RS07145	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BAD_RS07185	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BAD_RS07190	COG0489	protein tyrosine kinase activity
BAD_RS07260	COG2801	Transposase and inactivated derivatives
BAD_RS07305	COG1216	Glycosyl transferase, family 2
BAD_RS07315	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BAD_RS07320	COG1442	glycosyl transferase family 8
BAD_RS07320	COG1216	Glycosyl transferase, family 2
BAD_RS07335	COG0438	transferase activity, transferring glycosyl groups
BAD_RS07340	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BAD_RS07355	COG3177	Filamentation induced by cAMP protein fic
BAD_RS07360	COG2814	Major facilitator Superfamily
BAD_RS07365	COG5001	Diguanylate cyclase
BAD_RS07375	COG0656	L-ascorbic acid biosynthetic process
BAD_RS07390	COG1609	Transcriptional regulator
BAD_RS07405	COG0395	ABC-type sugar transport system, permease component
BAD_RS07410	COG1175	transmembrane transport
BAD_RS07415	COG1653	transport
BAD_RS07430	COG4988	ABC transporter
BAD_RS07455	COG1609	Transcriptional regulator
BAD_RS07465	COG0083	homoserine kinase activity
BAD_RS07470	COG0460	homoserine dehydrogenase
BAD_RS07475	COG0019	diaminopimelate decarboxylase activity
BAD_RS07485	COG0833	amino acid
BAD_RS07490	COG0251	oxidation-reduction process
BAD_RS07515	COG0545	Peptidyl-prolyl cis-trans isomerase
BAD_RS07525	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BAD_RS07560	COG0356	it plays a direct role in the translocation of protons across the membrane
BAD_RS07580	COG1131	(ABC) transporter
BAD_RS07600	COG2197	response regulator
BAD_RS07610	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BAD_RS07625	COG0745	RESPONSE REGULATOR receiver
BAD_RS07650	COG1605	Chorismate mutase
BAD_RS07650	COG0287	Prephenate dehydrogenase
BAD_RS07655	COG1522	sequence-specific DNA binding
BAD_RS07720	COG0179	Fumarylacetoacetate (FAA) hydrolase
BAD_RS07750	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BAD_RS07770	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BAD_RS07810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BAD_RS07830	COG2814	Major facilitator Superfamily
BAD_RS07845	COG1088	dTDP-glucose 4,6-dehydratase activity
BAD_RS07855	COG1368	sulfuric ester hydrolase activity
BAD_RS07860	COG1442	glycosyl transferase family 8
BAD_RS07860	COG1216	Glycosyl transferase, family 2
BAD_RS07865	COG1215	transferase activity, transferring glycosyl groups
BAD_RS07900	COG1088	dTDP-glucose 4,6-dehydratase activity
BAD_RS07980	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BAD_RS08000	COG0084	hydrolase, TatD family'
BAD_RS08035	COG1132	(ABC) transporter
BAD_RS08040	COG1132	(ABC) transporter
BAD_RS08090	COG0586	Pfam SNARE associated Golgi protein
BAD_RS08100	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BAD_RS08110	COG0789	Transcriptional regulator
BAD_RS08115	COG0484	heat shock protein binding
BAD_RS08135	COG0730	response to heat
BAD_RS08170	COG1609	Transcriptional regulator
BAD_RS08185	COG1523	belongs to the glycosyl hydrolase 13 family
BAD_RS08195	COG0366	Alpha amylase catalytic
BAD_RS08215	COG1609	Transcriptional regulator
BAD_RS08225	COG0588	phosphoglycerate mutase activity
BAD_RS08260	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BAD_RS08265	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BAD_RS08270	COG0366	Alpha amylase catalytic
BAD_RS08275	COG0395	ABC-type sugar transport system, permease component
BAD_RS08280	COG1175	transmembrane transport
BAD_RS08300	COG0037	tRNA processing
BAD_RS08300	COG0590	tRNA wobble adenosine to inosine editing
BAD_RS08305	COG0025	NhaP-type Na H and K H
BAD_RS08320	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BAD_RS08325	COG3250	beta-galactosidase activity
BAD_RS08335	COG1609	Transcriptional regulator
BAD_RS08345	COG1175	transmembrane transport
BAD_RS08350	COG0395	ABC-type sugar transport system, permease component
BAD_RS08375	COG3842	ATPase activity
BAD_RS08405	COG1472	Belongs to the glycosyl hydrolase 3 family
BAD_RS08455	COG3250	beta-galactosidase activity
BAD_RS08460	COG1609	Transcriptional regulator
BAD_RS08480	COG1472	Belongs to the glycosyl hydrolase 3 family
BAD_RS08540	COG0617	tRNA 3'-terminal CCA addition
BAD_RS08565	COG0492	ferredoxin-NADP+ reductase activity
BAD_RS08575	COG1192	Involved in chromosome partitioning
BAD_RS08585	COG1847	R3H domain protein
BAD_RS08625	COG0488	(ABC) transporter