locus-tag	class	description
F3K97_RS00010	COG0592	DNA-directed DNA polymerase activity
F3K97_RS00025	COG0187	DNA topoisomerase II activity
F3K97_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3K97_RS00040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
F3K97_RS00045	COG1970	mechanosensitive ion channel activity
F3K97_RS00070	COG1253	flavin adenine dinucleotide binding
F3K97_RS00075	COG0288	reversible hydration of carbon dioxide
F3K97_RS00085	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
F3K97_RS00095	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
F3K97_RS00100	COG0180	Tryptophanyl-tRNA synthetase
F3K97_RS00115	COG0058	SHG alpha-glucan phosphorylase activity
F3K97_RS00145	COG3764	Sortase (surface protein transpeptidase)
F3K97_RS00160	COG0515	serine threonine protein kinase
F3K97_RS00165	COG0768	penicillin binding
F3K97_RS00200	COG2197	response regulator
F3K97_RS00220	COG0071	Belongs to the small heat shock protein (HSP20) family
F3K97_RS00235	COG0343	queuine tRNA-ribosyltransferase activity
F3K97_RS00245	COG2217	Heavy metal translocating P-type atpase
F3K97_RS00250	COG0252	asparaginase activity
F3K97_RS00295	COG0191	fructose-bisphosphate aldolase activity
F3K97_RS00370	COG0477	Major facilitator Superfamily
F3K97_RS00390	COG1113	amino acid transport
F3K97_RS00400	COG0569	domain protein
F3K97_RS00400	COG0475	glutathione-regulated potassium exporter activity
F3K97_RS00450	COG1113	amino acid transport
F3K97_RS00470	COG0667	Aldo Keto reductase
F3K97_RS00475	COG1846	Transcriptional regulator
F3K97_RS00485	COG1132	(ABC) transporter
F3K97_RS00490	COG4989	oxidoreductase activity
F3K97_RS00500	COG0672	)-iron permease
F3K97_RS00505	COG3470	protein probably involved in high-affinity Fe2 transport
F3K97_RS00570	COG1215	transferase activity, transferring glycosyl groups
F3K97_RS00575	COG1309	transcriptional regulator
F3K97_RS00600	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
F3K97_RS00605	COG0305	Participates in initiation and elongation during chromosome replication
F3K97_RS00610	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F3K97_RS00615	COG3442	glutamine amidotransferase
F3K97_RS00640	COG1175	transmembrane transport
F3K97_RS00645	COG0395	ABC-type sugar transport system, permease component
F3K97_RS00660	COG3507	Belongs to the glycosyl hydrolase 43 family
F3K97_RS00665	COG0584	glycerophosphoryl diester phosphodiesterase
F3K97_RS00690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
F3K97_RS00795	COG1609	Transcriptional regulator
F3K97_RS00800	COG3940	Belongs to the glycosyl hydrolase 43 family
F3K97_RS00815	COG0395	ABC-type sugar transport system, permease component
F3K97_RS00830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3K97_RS00835	COG1260	myo-inositol-1-phosphate synthase
F3K97_RS00855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
F3K97_RS00855	COG1754	DNA topoisomerase type I activity
F3K97_RS00865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
F3K97_RS00870	COG1609	Transcriptional regulator
F3K97_RS00880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
F3K97_RS00970	COG0167	dihydroorotate dehydrogenase activity
F3K97_RS00975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
F3K97_RS01010	COG3842	ATPase activity
F3K97_RS01035	COG1309	transcriptional regulator
F3K97_RS01040	COG0436	Aminotransferase
F3K97_RS01045	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
F3K97_RS01055	COG3265	gluconokinase activity
F3K97_RS01070	COG2270	Major facilitator Superfamily
F3K97_RS01085	COG0742	ribosomal rna small subunit methyltransferase
F3K97_RS01100	COG1837	Belongs to the UPF0109 family
F3K97_RS01125	COG0505	Belongs to the CarA family
F3K97_RS01130	COG0488	(ABC) transporter
F3K97_RS01165	COG2197	response regulator
F3K97_RS01180	COG0440	acetolactate synthase activity
F3K97_RS01270	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
F3K97_RS01290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3K97_RS01295	COG1530	ribonuclease E activity
F3K97_RS01320	COG0436	Aminotransferase
F3K97_RS01330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3K97_RS01335	COG0250	Participates in transcription elongation, termination and antitermination
F3K97_RS01365	COG1268	BioY protein
F3K97_RS01370	COG4770	biotin carboxylase activity
F3K97_RS01375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
F3K97_RS01410	COG1704	LemA family
F3K97_RS01435	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
F3K97_RS01455	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
F3K97_RS01465	COG3579	cysteine-type endopeptidase activity
F3K97_RS01470	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3K97_RS01475	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
F3K97_RS01480	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
F3K97_RS01485	COG5002	protein histidine kinase activity
F3K97_RS01490	COG0745	RESPONSE REGULATOR receiver
F3K97_RS01520	COG2252	PERMEase
F3K97_RS01560	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
F3K97_RS01600	COG0812	UDP-N-acetylmuramate dehydrogenase activity
F3K97_RS01605	COG0531	amino acid
F3K97_RS01620	COG4166	transmembrane transport
F3K97_RS01625	COG0601	transmembrane transport
F3K97_RS01630	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3K97_RS01635	COG0444	Belongs to the ABC transporter superfamily
F3K97_RS01640	COG4608	Belongs to the ABC transporter superfamily
F3K97_RS01645	COG3507	Belongs to the glycosyl hydrolase 43 family
F3K97_RS01660	COG3507	Belongs to the glycosyl hydrolase 43 family
F3K97_RS01665	COG2272	Belongs to the type-B carboxylesterase lipase family
F3K97_RS01675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3K97_RS01685	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
F3K97_RS01690	COG1739	Uncharacterized protein family UPF0029
F3K97_RS01735	COG1063	alcohol dehydrogenase
F3K97_RS01745	COG1454	alcohol dehydrogenase
F3K97_RS01745	COG1012	belongs to the aldehyde dehydrogenase family
F3K97_RS01795	COG0255	Belongs to the universal ribosomal protein uL29 family
F3K97_RS01900	COG2308	Evidence 4 Homologs of previously reported genes of
F3K97_RS01940	COG0196	riboflavin kinase activity
F3K97_RS01965	COG0328	RNA-DNA hybrid ribonuclease activity
F3K97_RS01970	COG3290	protein histidine kinase activity
F3K97_RS01990	COG3711	transcriptional antiterminator
F3K97_RS01995	COG1803	Methylglyoxal synthase
F3K97_RS01995	COG1597	lipid kinase activity
F3K97_RS02035	COG2814	Major facilitator Superfamily
F3K97_RS02045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
F3K97_RS02050	COG1575	Belongs to the MenA family. Type 1 subfamily
F3K97_RS02060	COG4716	Myosin-crossreactive antigen
F3K97_RS02065	COG0704	Plays a role in the regulation of phosphate uptake
F3K97_RS02070	COG5002	protein histidine kinase activity
F3K97_RS02080	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
F3K97_RS02085	COG1705	Flagellar rod assembly protein muramidase FlgJ
F3K97_RS02085	COG3942	CHAP domain
F3K97_RS02090	COG0791	NLP P60 protein
F3K97_RS02095	COG0589	response to stress
F3K97_RS02130	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
F3K97_RS02195	COG1716	ATPase activity
F3K97_RS02195	COG5001	Diguanylate cyclase
F3K97_RS02200	COG1454	alcohol dehydrogenase
F3K97_RS02205	COG1216	Glycosyl transferase, family 2
F3K97_RS02230	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
F3K97_RS02245	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
F3K97_RS02255	COG1946	Acyl-CoA thioesterase
F3K97_RS02270	COG0242	peptide deformylase activity
F3K97_RS02300	COG3507	Belongs to the glycosyl hydrolase 43 family
F3K97_RS02305	COG1609	Transcriptional regulator
F3K97_RS02320	COG0395	ABC-type sugar transport system, permease component
F3K97_RS02325	COG3507	Belongs to the glycosyl hydrolase 43 family
F3K97_RS02335	COG2272	Belongs to the type-B carboxylesterase lipase family
F3K97_RS02345	COG1070	Carbohydrate kinase
F3K97_RS02350	COG1940	carbohydrate kinase activity
F3K97_RS02375	COG1874	Beta-galactosidase
F3K97_RS02405	COG3459	Glycosyltransferase 36 associated
F3K97_RS02455	COG0009	L-threonylcarbamoyladenylate synthase
F3K97_RS02460	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
F3K97_RS02470	COG1609	Transcriptional regulator
F3K97_RS02475	COG0366	Alpha amylase catalytic
F3K97_RS02490	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3K97_RS02510	COG3590	peptidase
F3K97_RS02515	COG0024	Methionine aminopeptidase
F3K97_RS02535	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
F3K97_RS02540	COG2884	Cell division ATP-binding protein ftsE
F3K97_RS02545	COG2177	Part of the ABC transporter FtsEX involved in
F3K97_RS02550	COG3942	CHAP domain
F3K97_RS02550	COG1388	LysM domain
F3K97_RS02570	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3K97_RS02585	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
F3K97_RS02610	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
F3K97_RS02615	COG0747	negative chemotaxis
F3K97_RS02625	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3K97_RS02635	COG4608	Belongs to the ABC transporter superfamily
F3K97_RS02655	COG0514	ATP-dependent DNA helicase (RecQ)
F3K97_RS02670	COG0531	amino acid
F3K97_RS02675	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
F3K97_RS02685	COG0358	DNA primase activity
F3K97_RS02730	COG0765	amino acid transport
F3K97_RS02735	COG0765	amino acid transport
F3K97_RS02740	COG1126	abc transporter atp-binding protein
F3K97_RS02765	COG0577	efflux transmembrane transporter activity
F3K97_RS02765	COG1136	(ABC) transporter
F3K97_RS02775	COG0577	efflux transmembrane transporter activity
F3K97_RS02780	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
F3K97_RS02785	COG0604	alcohol dehydrogenase
F3K97_RS02790	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
F3K97_RS02795	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
F3K97_RS02805	COG1368	sulfuric ester hydrolase activity
F3K97_RS02825	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
F3K97_RS02835	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
F3K97_RS02865	COG0385	Bile acid
F3K97_RS02910	COG0284	orotidine-5'-phosphate decarboxylase activity
F3K97_RS02935	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
F3K97_RS02940	COG1011	Hydrolase
F3K97_RS02950	COG0560	Phosphoserine phosphatase
F3K97_RS02960	COG4122	O-methyltransferase activity
F3K97_RS03000	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
F3K97_RS03040	COG0714	Associated with various cellular activities
F3K97_RS03070	COG0745	RESPONSE REGULATOR receiver
F3K97_RS03075	COG2205	protein histidine kinase activity
F3K97_RS03080	COG1278	Cold shock
F3K97_RS03090	COG0589	response to stress
F3K97_RS03095	COG0542	response to heat
F3K97_RS03100	COG1196	nuclear chromosome segregation
F3K97_RS03115	COG0765	amino acid transport
F3K97_RS03125	COG1126	abc transporter atp-binding protein
F3K97_RS03130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3K97_RS03135	COG0765	amino acid transport
F3K97_RS03140	COG0765	amino acid transport
F3K97_RS03145	COG2326	polyphosphate kinase activity
F3K97_RS03150	COG4581	dead DEAH box helicase
F3K97_RS03160	COG2814	Major facilitator Superfamily
F3K97_RS03200	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
F3K97_RS03205	COG1053	succinate dehydrogenase
F3K97_RS03210	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
F3K97_RS03210	COG0758	DNA mediated transformation
F3K97_RS03215	COG0606	chelatase, subunit chli
F3K97_RS03240	COG1122	ATPase activity
F3K97_RS03245	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
F3K97_RS03255	COG1136	(ABC) transporter
F3K97_RS03260	COG0577	efflux transmembrane transporter activity
F3K97_RS03260	COG1136	(ABC) transporter
F3K97_RS03265	COG2197	response regulator
F3K97_RS03270	COG4585	Histidine kinase
F3K97_RS03280	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
F3K97_RS03285	COG0012	GTP binding
F3K97_RS03290	COG4974	Belongs to the 'phage' integrase family
F3K97_RS03380	COG2814	Major facilitator Superfamily
F3K97_RS03405	COG1918	ferrous iron import across plasma membrane
F3K97_RS03405	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
F3K97_RS03480	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
F3K97_RS03480	COG3236	hydrolase activity, hydrolyzing N-glycosyl compounds
F3K97_RS03490	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
F3K97_RS03495	COG2207	Transcriptional regulator
F3K97_RS03495	COG1917	Cupin 2, conserved barrel domain protein
F3K97_RS03505	COG2233	PERMEase
F3K97_RS03510	COG4221	oxidoreductase activity
F3K97_RS03520	COG0390	transport system, permease component
F3K97_RS03525	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
F3K97_RS03535	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
F3K97_RS03540	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
F3K97_RS03545	COG0363	glucosamine-6-phosphate deaminase activity
F3K97_RS03565	COG0300	oxidoreductase activity
F3K97_RS03580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
F3K97_RS03590	COG2249	NAD(P)H dehydrogenase (quinone) activity
F3K97_RS03595	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
F3K97_RS03600	COG1687	branched-chain amino acid
F3K97_RS03660	COG1760	l-serine dehydratase
F3K97_RS03670	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
F3K97_RS03695	COG1316	TRANSCRIPTIONal
F3K97_RS03700	COG1316	TRANSCRIPTIONal
F3K97_RS03735	COG2205	protein histidine kinase activity
F3K97_RS03740	COG0745	RESPONSE REGULATOR receiver
F3K97_RS03765	COG1121	(ABC) transporter
F3K97_RS03770	COG0803	Belongs to the bacterial solute-binding protein 9 family
F3K97_RS03780	COG0539	negative regulation of cytoplasmic translation
F3K97_RS03800	COG0469	pyruvate kinase activity
F3K97_RS03820	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
F3K97_RS03825	COG1051	belongs to the nudix hydrolase family
F3K97_RS03865	COG0857	belongs to the CobB CobQ family
F3K97_RS03865	COG0280	phosphate acetyltransferase
F3K97_RS03870	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
F3K97_RS03960	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
F3K97_RS03970	COG1523	belongs to the glycosyl hydrolase 13 family
F3K97_RS03990	COG0396	ATPase activity
F3K97_RS04000	COG0822	iron-sulfur transferase activity
F3K97_RS04005	COG2151	metal-sulfur cluster biosynthetic enzyme
F3K97_RS04025	COG1385	rRNA (uridine-N3-)-methyltransferase activity
F3K97_RS04030	COG0537	adenosine 5'-monophosphoramidase activity
F3K97_RS04060	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F3K97_RS04065	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
F3K97_RS04070	COG1282	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane
F3K97_RS04080	COG0534	Mate efflux family protein
F3K97_RS04090	COG0667	Aldo Keto reductase
F3K97_RS04105	COG2814	Major facilitator Superfamily
F3K97_RS04130	COG1129	ABC transporter
F3K97_RS04140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
F3K97_RS04160	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
F3K97_RS04165	COG2860	membrane
F3K97_RS04185	COG0069	glutamate synthase activity
F3K97_RS04185	COG0067	glutamate synthase
F3K97_RS04185	COG0070	glutamate synthase
F3K97_RS04200	COG0297	glycogen (starch) synthase activity
F3K97_RS04205	COG1119	ATPase activity
F3K97_RS04230	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
F3K97_RS04250	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F3K97_RS04255	COG0284	orotidine-5'-phosphate decarboxylase activity
F3K97_RS04260	COG0543	2 iron, 2 sulfur cluster binding
F3K97_RS04265	COG0167	dihydroorotate dehydrogenase activity
F3K97_RS04275	COG0583	DNA-binding transcription factor activity
F3K97_RS04290	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
F3K97_RS04290	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
F3K97_RS04295	COG0577	efflux transmembrane transporter activity
F3K97_RS04295	COG1136	(ABC) transporter
F3K97_RS04320	COG1022	Amp-dependent synthetase and ligase
F3K97_RS04335	COG0516	GMP reductase activity
F3K97_RS04400	COG0133	tryptophan synthase activity
F3K97_RS04415	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
F3K97_RS04455	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3K97_RS04490	COG0045	succinate-CoA ligase (ADP-forming) activity
F3K97_RS04530	COG4974	Belongs to the 'phage' integrase family
F3K97_RS04580	COG2801	Transposase and inactivated derivatives
F3K97_RS04800	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
F3K97_RS04820	COG1674	ftsk spoiiie
F3K97_RS04900	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
F3K97_RS05060	COG1388	LysM domain
F3K97_RS05060	COG3942	CHAP domain
F3K97_RS05280	COG0675	Transposase, IS605 OrfB family
F3K97_RS05355	COG2801	Transposase and inactivated derivatives
F3K97_RS05370	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3K97_RS05545	COG0675	Transposase, IS605 OrfB family
F3K97_RS05820	COG1716	ATPase activity
F3K97_RS05880	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
F3K97_RS05885	COG0436	Aminotransferase
F3K97_RS05890	COG0561	phosphatase activity
F3K97_RS05895	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
F3K97_RS05995	COG1335	isochorismatase
F3K97_RS06000	COG1122	ATPase activity
F3K97_RS06005	COG0488	(ABC) transporter
F3K97_RS06015	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
F3K97_RS06055	COG0802	atpase or kinase
F3K97_RS06065	COG2333	competence protein COMEC
F3K97_RS06065	COG0658	competence protein
F3K97_RS06070	COG1596	polysaccharide export
F3K97_RS06070	COG1555	photosystem II stabilization
F3K97_RS06080	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
F3K97_RS06085	COG0598	Magnesium transport protein CorA
F3K97_RS06090	COG0406	alpha-ribazole phosphatase activity
F3K97_RS06105	COG0406	alpha-ribazole phosphatase activity
F3K97_RS06125	COG0667	Aldo Keto reductase
F3K97_RS06150	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
F3K97_RS06150	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
F3K97_RS06155	COG1397	ADP-ribosylglycohydrolase
F3K97_RS06160	COG2188	Transcriptional regulator
F3K97_RS06165	COG1028	Short-chain dehydrogenase reductase Sdr
F3K97_RS06170	COG1335	isochorismatase
F3K97_RS06200	COG3328	transposase activity
F3K97_RS06330	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
F3K97_RS06355	COG1028	Short-chain dehydrogenase reductase Sdr
F3K97_RS06365	COG0577	efflux transmembrane transporter activity
F3K97_RS06390	COG0640	Transcriptional regulator
F3K97_RS06395	COG0456	acetyltransferase
F3K97_RS06405	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
F3K97_RS06450	COG1028	Short-chain dehydrogenase reductase Sdr
F3K97_RS06460	COG1484	DNA-dependent DNA replication
F3K97_RS06505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3K97_RS06510	COG0497	DNA recombination
F3K97_RS06520	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
F3K97_RS06525	COG0569	domain protein
F3K97_RS06620	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
F3K97_RS06630	COG1136	(ABC) transporter
F3K97_RS06650	COG1028	Short-chain dehydrogenase reductase Sdr
F3K97_RS06665	COG1611	Belongs to the LOG family
F3K97_RS06695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
F3K97_RS06705	COG1122	ATPase activity
F3K97_RS06710	COG4721	ABC-type cobalt transport system, permease component
F3K97_RS06740	COG1122	ATPase activity
F3K97_RS06760	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
F3K97_RS06785	COG3579	cysteine-type endopeptidase activity
F3K97_RS06795	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
F3K97_RS06800	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3K97_RS06820	COG3189	MarR family transcriptional regulator
F3K97_RS06825	COG4096	Type I site-specific restriction-modification system, R (Restriction) subunit and related
F3K97_RS06845	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
F3K97_RS06855	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
F3K97_RS06875	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
F3K97_RS06875	COG1199	ATP-dependent helicase activity
F3K97_RS06880	COG2040	homocysteine
F3K97_RS06905	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
F3K97_RS06910	COG1882	Formate acetyltransferase
F3K97_RS06925	COG1473	amidohydrolase
F3K97_RS06935	COG1464	Belongs to the NlpA lipoprotein family
F3K97_RS06945	COG2011	ABC-type metal ion transport system permease component
F3K97_RS06960	COG4974	Belongs to the 'phage' integrase family
F3K97_RS06980	COG3328	transposase activity
F3K97_RS07055	COG3177	Filamentation induced by cAMP protein fic
F3K97_RS07260	COG1192	Involved in chromosome partitioning
F3K97_RS07305	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
F3K97_RS07330	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
F3K97_RS07335	COG1201	RNA secondary structure unwinding
F3K97_RS07345	COG0187	DNA topoisomerase II activity
F3K97_RS07350	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
F3K97_RS07360	COG0142	geranyltranstransferase activity
F3K97_RS07385	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
F3K97_RS07395	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
F3K97_RS07405	COG2137	regulation of response to DNA damage stimulus
F3K97_RS07420	COG1396	sequence-specific DNA binding
F3K97_RS07425	COG1058	Belongs to the CinA family
F3K97_RS07425	COG1546	Belongs to the CinA family
F3K97_RS07430	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
F3K97_RS07450	COG2357	RelA SpoT domain protein
F3K97_RS07460	COG0670	Belongs to the BI1 family
F3K97_RS07485	COG2197	response regulator
F3K97_RS07490	COG4585	Histidine kinase
F3K97_RS07495	COG1131	(ABC) transporter
F3K97_RS07520	COG0110	maltose O-acetyltransferase activity
F3K97_RS07525	COG2207	Transcriptional regulator
F3K97_RS07545	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
F3K97_RS07575	COG0708	Exodeoxyribonuclease III
F3K97_RS07585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
F3K97_RS07590	COG0601	transmembrane transport
F3K97_RS07595	COG4166	transmembrane transport
F3K97_RS07605	COG0577	efflux transmembrane transporter activity
F3K97_RS07605	COG1136	(ABC) transporter
F3K97_RS07610	COG0577	efflux transmembrane transporter activity
F3K97_RS07620	COG0287	Prephenate dehydrogenase
F3K97_RS07640	COG0477	Major facilitator Superfamily
F3K97_RS07670	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
F3K97_RS07675	COG0367	asparagine synthase
F3K97_RS07690	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
F3K97_RS07700	COG2017	converts alpha-aldose to the beta-anomer
F3K97_RS07710	COG1595	DNA-templated transcription, initiation
F3K97_RS07725	COG1794	racemase activity, acting on amino acids and derivatives
F3K97_RS07730	COG0285	dihydrofolate synthase activity
F3K97_RS07735	COG0006	proline dipeptidase activity
F3K97_RS07755	COG0601	transmembrane transport
F3K97_RS07815	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
F3K97_RS07825	COG0768	penicillin binding
F3K97_RS07850	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
F3K97_RS07880	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
F3K97_RS07885	COG2813	Specifically methylates the guanine in position
F3K97_RS07890	COG1643	Atp-dependent helicase
F3K97_RS07905	COG1136	(ABC) transporter
F3K97_RS07925	COG0745	RESPONSE REGULATOR receiver
F3K97_RS07935	COG2814	Major facilitator Superfamily
F3K97_RS07950	COG0174	glutamine synthetase
F3K97_RS07985	COG0587	DNA-directed DNA polymerase activity
F3K97_RS08015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
F3K97_RS08045	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
F3K97_RS08075	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
F3K97_RS08130	COG0352	thiamine-phosphate diphosphorylase activity
F3K97_RS08130	COG0351	phosphomethylpyrimidine kinase
F3K97_RS08155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
F3K97_RS08210	COG3480	Lon protease (S16) C-terminal proteolytic domain
F3K97_RS08235	COG0613	PHP domain protein
F3K97_RS08245	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
F3K97_RS08270	COG0747	negative chemotaxis
F3K97_RS08295	COG1518	maintenance of DNA repeat elements
F3K97_RS08300	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
F3K97_RS08315	COG1609	Transcriptional regulator
F3K97_RS08330	COG1132	(ABC) transporter
F3K97_RS08335	COG1132	(ABC) transporter
F3K97_RS08355	COG1929	Belongs to the glycerate kinase type-1 family
F3K97_RS08360	COG0477	Major facilitator Superfamily
F3K97_RS08365	COG0671	phosphoesterase, PA-phosphatase related
F3K97_RS08380	COG1309	transcriptional regulator
F3K97_RS08390	COG3507	Belongs to the glycosyl hydrolase 43 family
F3K97_RS08450	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
F3K97_RS08450	COG1328	CTP reductase activity
F3K97_RS08455	COG1570	exodeoxyribonuclease VII activity
F3K97_RS08460	COG1722	exodeoxyribonuclease VII activity
F3K97_RS08485	COG1192	Involved in chromosome partitioning
F3K97_RS08500	COG0248	Ppx GppA phosphatase
F3K97_RS08520	COG0210	DNA helicase
F3K97_RS08525	COG0494	nUDIX hydrolase
F3K97_RS08575	COG0076	glutamate decarboxylase activity
F3K97_RS08580	COG0531	amino acid
F3K97_RS08600	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
F3K97_RS08610	COG2807	transmembrane transport
F3K97_RS08620	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
F3K97_RS08630	COG1937	Protein conserved in bacteria
F3K97_RS08660	COG2815	serine threonine protein kinase
F3K97_RS08660	COG0515	serine threonine protein kinase
F3K97_RS08670	COG0714	Associated with various cellular activities
F3K97_RS08685	COG0631	protein serine/threonine phosphatase activity
F3K97_RS08720	COG1194	a g-specific adenine glycosylase
F3K97_RS08725	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
F3K97_RS08740	COG1621	beta-fructofuranosidase activity
F3K97_RS08755	COG0395	ABC-type sugar transport system, permease component
F3K97_RS08760	COG4209	transmembrane transport
F3K97_RS08770	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
F3K97_RS08780	COG1349	DNA-binding transcription factor activity
F3K97_RS08785	COG0167	dihydroorotate dehydrogenase activity
F3K97_RS08790	COG1902	pentaerythritol trinitrate reductase activity
F3K97_RS08795	COG4499	WXG100 protein secretion system (Wss), protein YukC
F3K97_RS08795	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
F3K97_RS08805	COG0095	Lipoate-protein ligase
F3K97_RS08845	COG1376	ErfK ybiS ycfS ynhG family protein
F3K97_RS08865	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
F3K97_RS08885	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
F3K97_RS08895	COG0489	protein tyrosine kinase activity
F3K97_RS08995	COG1088	dTDP-glucose 4,6-dehydratase activity
F3K97_RS09000	COG0366	Alpha amylase catalytic
F3K97_RS09030	COG3328	transposase activity
F3K97_RS09055	COG1216	Glycosyl transferase, family 2
F3K97_RS09070	COG0297	glycogen (starch) synthase activity
F3K97_RS09080	COG0366	Alpha amylase catalytic
F3K97_RS09085	COG0366	Alpha amylase catalytic
F3K97_RS09090	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
F3K97_RS09095	COG3177	Filamentation induced by cAMP protein fic
F3K97_RS09105	COG2814	Major facilitator Superfamily
F3K97_RS09110	COG5001	Diguanylate cyclase
F3K97_RS09120	COG0656	L-ascorbic acid biosynthetic process
F3K97_RS09130	COG1609	Transcriptional regulator
F3K97_RS09155	COG4988	ABC transporter
F3K97_RS09180	COG1609	Transcriptional regulator
F3K97_RS09190	COG0083	homoserine kinase activity
F3K97_RS09195	COG0460	homoserine dehydrogenase
F3K97_RS09200	COG0019	diaminopimelate decarboxylase activity
F3K97_RS09210	COG0833	amino acid
F3K97_RS09215	COG0251	oxidation-reduction process
F3K97_RS09240	COG0545	Peptidyl-prolyl cis-trans isomerase
F3K97_RS09250	COG0355	proton-transporting ATP synthase activity, rotational mechanism
F3K97_RS09285	COG0356	it plays a direct role in the translocation of protons across the membrane
F3K97_RS09340	COG4974	Belongs to the 'phage' integrase family
F3K97_RS09350	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
F3K97_RS09365	COG0745	RESPONSE REGULATOR receiver
F3K97_RS09390	COG0287	Prephenate dehydrogenase
F3K97_RS09390	COG1605	Chorismate mutase
F3K97_RS09395	COG1522	sequence-specific DNA binding
F3K97_RS09445	COG1322	Protein conserved in bacteria
F3K97_RS09460	COG0179	Fumarylacetoacetate (FAA) hydrolase
F3K97_RS09480	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
F3K97_RS09500	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
F3K97_RS09540	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
F3K97_RS09560	COG1088	dTDP-glucose 4,6-dehydratase activity
F3K97_RS09570	COG1368	sulfuric ester hydrolase activity
F3K97_RS09580	COG1442	glycosyl transferase family 8
F3K97_RS09595	COG1216	Glycosyl transferase, family 2
F3K97_RS09605	COG1442	glycosyl transferase family 8
F3K97_RS09680	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
F3K97_RS09700	COG0084	hydrolase, TatD family'
F3K97_RS09730	COG1132	(ABC) transporter
F3K97_RS09735	COG1132	(ABC) transporter
F3K97_RS09785	COG0586	Pfam SNARE associated Golgi protein
F3K97_RS09795	COG1373	ATPase (AAA superfamily
F3K97_RS09800	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
F3K97_RS09810	COG0789	Transcriptional regulator
F3K97_RS09815	COG0484	heat shock protein binding
F3K97_RS09835	COG0730	response to heat
F3K97_RS09860	COG1609	Transcriptional regulator
F3K97_RS09870	COG0546	phosphoglycolate phosphatase activity
F3K97_RS09875	COG1523	belongs to the glycosyl hydrolase 13 family
F3K97_RS09880	COG3833	ABC-type maltose transport systems, permease component
F3K97_RS09885	COG1175	transmembrane transport
F3K97_RS09925	COG1609	Transcriptional regulator
F3K97_RS09935	COG0588	phosphoglycerate mutase activity
F3K97_RS09970	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
F3K97_RS09975	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
F3K97_RS09990	COG1175	transmembrane transport
F3K97_RS10010	COG0590	tRNA wobble adenosine to inosine editing
F3K97_RS10010	COG0037	tRNA processing
F3K97_RS10015	COG0025	NhaP-type Na H and K H
F3K97_RS10035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
F3K97_RS10040	COG3250	beta-galactosidase activity
F3K97_RS10050	COG1609	Transcriptional regulator
F3K97_RS10080	COG3842	ATPase activity
F3K97_RS10085	COG2204	response regulator
F3K97_RS10150	COG0577	efflux transmembrane transporter activity
F3K97_RS10175	COG0450	alkyl hydroperoxide reductase
F3K97_RS10200	COG1472	Belongs to the glycosyl hydrolase 3 family
F3K97_RS10240	COG0617	tRNA 3'-terminal CCA addition
F3K97_RS10265	COG0492	ferredoxin-NADP+ reductase activity
F3K97_RS10275	COG1192	Involved in chromosome partitioning
F3K97_RS10285	COG1847	R3H domain protein