locus-tag	class	description
FVF64_RS00005	COG0783	Belongs to the Dps family
FVF64_RS00010	COG1253	flavin adenine dinucleotide binding
FVF64_RS00015	COG0288	reversible hydration of carbon dioxide
FVF64_RS00020	COG1609	Transcriptional regulator
FVF64_RS00040	COG1609	Transcriptional regulator
FVF64_RS00045	COG3534	alpha-L-arabinofuranosidase
FVF64_RS00065	COG0656	L-ascorbic acid biosynthetic process
FVF64_RS00070	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FVF64_RS00085	COG0180	Tryptophanyl-tRNA synthetase
FVF64_RS00100	COG0058	SHG alpha-glucan phosphorylase activity
FVF64_RS00140	COG3764	Sortase (surface protein transpeptidase)
FVF64_RS00155	COG0515	serine threonine protein kinase
FVF64_RS00160	COG0768	penicillin binding
FVF64_RS00195	COG0697	spore germination
FVF64_RS00210	COG2226	methyltransferase
FVF64_RS00220	COG2261	transglycosylase associated protein
FVF64_RS00225	COG2261	transglycosylase associated protein
FVF64_RS00250	COG2217	Heavy metal translocating P-type atpase
FVF64_RS00255	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
FVF64_RS00270	COG0343	queuine tRNA-ribosyltransferase activity
FVF64_RS00295	COG2814	Major facilitator Superfamily
FVF64_RS00310	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FVF64_RS00340	COG0667	Aldo Keto reductase
FVF64_RS00380	COG1063	alcohol dehydrogenase
FVF64_RS00385	COG0583	DNA-binding transcription factor activity
FVF64_RS00395	COG0191	fructose-bisphosphate aldolase activity
FVF64_RS00405	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FVF64_RS00455	COG2211	Major facilitator Superfamily
FVF64_RS00465	COG4770	biotin carboxylase activity
FVF64_RS00495	COG0477	Major facilitator Superfamily
FVF64_RS00555	COG1132	(ABC) transporter
FVF64_RS00560	COG0390	transport system, permease component
FVF64_RS00565	COG1113	amino acid transport
FVF64_RS00570	COG1136	(ABC) transporter
FVF64_RS00570	COG0577	efflux transmembrane transporter activity
FVF64_RS00580	COG1113	amino acid transport
FVF64_RS00595	COG0577	efflux transmembrane transporter activity
FVF64_RS00600	COG1136	(ABC) transporter
FVF64_RS00600	COG0577	efflux transmembrane transporter activity
FVF64_RS00610	COG1846	Transcriptional regulator
FVF64_RS00630	COG0671	phosphoesterase, PA-phosphatase related
FVF64_RS00635	COG0110	maltose O-acetyltransferase activity
FVF64_RS00680	COG1129	ABC transporter
FVF64_RS00715	COG1309	transcriptional regulator
FVF64_RS00735	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FVF64_RS00745	COG0305	Participates in initiation and elongation during chromosome replication
FVF64_RS00750	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FVF64_RS00785	COG0406	alpha-ribazole phosphatase activity
FVF64_RS00785	COG0494	nUDIX hydrolase
FVF64_RS00880	COG1260	myo-inositol-1-phosphate synthase
FVF64_RS00895	COG1754	DNA topoisomerase type I activity
FVF64_RS00895	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FVF64_RS00960	COG0406	alpha-ribazole phosphatase activity
FVF64_RS01020	COG0446	pyridine nucleotide-disulphide oxidoreductase
FVF64_RS01030	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FVF64_RS01085	COG0436	Aminotransferase
FVF64_RS01100	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FVF64_RS01100	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FVF64_RS01110	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
FVF64_RS01125	COG0742	ribosomal rna small subunit methyltransferase
FVF64_RS01140	COG1837	Belongs to the UPF0109 family
FVF64_RS01180	COG0488	(ABC) transporter
FVF64_RS01190	COG0440	acetolactate synthase activity
FVF64_RS01230	COG0667	Aldo Keto reductase
FVF64_RS01300	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FVF64_RS01320	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FVF64_RS01325	COG1530	ribonuclease E activity
FVF64_RS01365	COG0436	Aminotransferase
FVF64_RS01400	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
FVF64_RS01400	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
FVF64_RS01405	COG1268	BioY protein
FVF64_RS01410	COG4770	biotin carboxylase activity
FVF64_RS01415	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FVF64_RS01440	COG0039	L-malate dehydrogenase activity
FVF64_RS01455	COG1704	LemA family
FVF64_RS01465	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FVF64_RS01470	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FVF64_RS01490	COG0826	peptidase U32
FVF64_RS01510	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FVF64_RS01520	COG3579	cysteine-type endopeptidase activity
FVF64_RS01525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FVF64_RS01530	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FVF64_RS01530	COG2755	lipolytic protein G-D-S-L family
FVF64_RS01535	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FVF64_RS01540	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FVF64_RS01550	COG0745	RESPONSE REGULATOR receiver
FVF64_RS01565	COG0581	inorganic phosphate transmembrane transporter activity
FVF64_RS01575	COG2252	PERMEase
FVF64_RS01660	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FVF64_RS01665	COG0531	amino acid
FVF64_RS01680	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FVF64_RS01690	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
FVF64_RS01695	COG1739	Uncharacterized protein family UPF0029
FVF64_RS01730	COG1012	belongs to the aldehyde dehydrogenase family
FVF64_RS01730	COG1454	alcohol dehydrogenase
FVF64_RS01790	COG0255	Belongs to the universal ribosomal protein uL29 family
FVF64_RS01925	COG0196	riboflavin kinase activity
FVF64_RS01950	COG0328	RNA-DNA hybrid ribonuclease activity
FVF64_RS01970	COG1803	Methylglyoxal synthase
FVF64_RS01970	COG1597	lipid kinase activity
FVF64_RS01995	COG2197	response regulator
FVF64_RS02015	COG0626	cystathionine gamma-synthase activity
FVF64_RS02025	COG2873	o-acetylhomoserine
FVF64_RS02035	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FVF64_RS02050	COG3579	cysteine-type endopeptidase activity
FVF64_RS02055	COG0531	amino acid
FVF64_RS02065	COG1113	amino acid transport
FVF64_RS02080	COG4716	Myosin-crossreactive antigen
FVF64_RS02085	COG1063	alcohol dehydrogenase
FVF64_RS02090	COG1028	Short-chain dehydrogenase reductase Sdr
FVF64_RS02090	COG3321	synthase
FVF64_RS02090	COG0604	alcohol dehydrogenase
FVF64_RS02100	COG5002	protein histidine kinase activity
FVF64_RS02105	COG0704	Plays a role in the regulation of phosphate uptake
FVF64_RS02110	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FVF64_RS02115	COG1705	Flagellar rod assembly protein muramidase FlgJ
FVF64_RS02115	COG3942	CHAP domain
FVF64_RS02120	COG0791	NLP P60 protein
FVF64_RS02120	COG1388	LysM domain
FVF64_RS02140	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
FVF64_RS02145	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FVF64_RS02150	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FVF64_RS02230	COG3189	MarR family transcriptional regulator
FVF64_RS02240	COG3250	beta-galactosidase activity
FVF64_RS02245	COG1609	Transcriptional regulator
FVF64_RS02280	COG0395	ABC-type sugar transport system, permease component
FVF64_RS02310	COG1216	Glycosyl transferase, family 2
FVF64_RS02315	COG0628	permease
FVF64_RS02350	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FVF64_RS02365	COG1946	Acyl-CoA thioesterase
FVF64_RS02375	COG0242	peptide deformylase activity
FVF64_RS02380	COG2873	o-acetylhomoserine
FVF64_RS02415	COG3507	Belongs to the glycosyl hydrolase 43 family
FVF64_RS02430	COG1175	transmembrane transport
FVF64_RS02440	COG3507	Belongs to the glycosyl hydrolase 43 family
FVF64_RS02450	COG2272	Belongs to the type-B carboxylesterase lipase family
FVF64_RS02460	COG1070	Carbohydrate kinase
FVF64_RS02465	COG1940	carbohydrate kinase activity
FVF64_RS02485	COG0009	L-threonylcarbamoyladenylate synthase
FVF64_RS02505	COG0561	phosphatase activity
FVF64_RS02510	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FVF64_RS02530	COG3590	peptidase
FVF64_RS02540	COG0024	Methionine aminopeptidase
FVF64_RS02545	COG0372	Belongs to the citrate synthase family
FVF64_RS02565	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FVF64_RS02570	COG2884	Cell division ATP-binding protein ftsE
FVF64_RS02580	COG1388	LysM domain
FVF64_RS02580	COG3942	CHAP domain
FVF64_RS02600	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVF64_RS02605	COG0765	amino acid transport
FVF64_RS02620	COG2198	Histidine kinase
FVF64_RS02620	COG2205	protein histidine kinase activity
FVF64_RS02620	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVF64_RS02620	COG0784	Response regulator, receiver
FVF64_RS02625	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FVF64_RS02645	COG0747	negative chemotaxis
FVF64_RS02650	COG0601	transmembrane transport
FVF64_RS02655	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVF64_RS02665	COG4172	Belongs to the ABC transporter superfamily
FVF64_RS02680	COG0514	ATP-dependent DNA helicase (RecQ)
FVF64_RS02760	COG0371	Dehydrogenase
FVF64_RS02775	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FVF64_RS02780	COG0358	DNA primase activity
FVF64_RS02785	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FVF64_RS02795	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FVF64_RS02800	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FVF64_RS02805	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FVF64_RS02810	COG0735	belongs to the Fur family
FVF64_RS02815	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FVF64_RS02820	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
FVF64_RS02825	COG0151	Belongs to the GarS family
FVF64_RS02840	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FVF64_RS02895	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FVF64_RS02975	COG0284	orotidine-5'-phosphate decarboxylase activity
FVF64_RS03000	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FVF64_RS03015	COG0560	Phosphoserine phosphatase
FVF64_RS03020	COG0586	Pfam SNARE associated Golgi protein
FVF64_RS03030	COG4122	O-methyltransferase activity
FVF64_RS03060	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FVF64_RS03100	COG0714	Associated with various cellular activities
FVF64_RS03115	COG1278	Cold shock
FVF64_RS03135	COG0745	RESPONSE REGULATOR receiver
FVF64_RS03140	COG2205	protein histidine kinase activity
FVF64_RS03145	COG1278	Cold shock
FVF64_RS03180	COG1196	nuclear chromosome segregation
FVF64_RS03190	COG1126	abc transporter atp-binding protein
FVF64_RS03195	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVF64_RS03200	COG0765	amino acid transport
FVF64_RS03205	COG0765	amino acid transport
FVF64_RS03210	COG2326	polyphosphate kinase activity
FVF64_RS03225	COG2814	Major facilitator Superfamily
FVF64_RS03230	COG1022	Amp-dependent synthetase and ligase
FVF64_RS03235	COG3328	transposase activity
FVF64_RS03260	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
FVF64_RS03270	COG0656	L-ascorbic acid biosynthetic process
FVF64_RS03295	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
FVF64_RS03315	COG2151	metal-sulfur cluster biosynthetic enzyme
FVF64_RS03315	COG0489	protein tyrosine kinase activity
FVF64_RS03320	COG4721	ABC-type cobalt transport system, permease component
FVF64_RS03345	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FVF64_RS03385	COG4721	ABC-type cobalt transport system, permease component
FVF64_RS03390	COG4172	Belongs to the ABC transporter superfamily
FVF64_RS03395	COG1136	(ABC) transporter
FVF64_RS03400	COG0577	efflux transmembrane transporter activity
FVF64_RS03410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FVF64_RS03500	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FVF64_RS03505	COG0569	domain protein
FVF64_RS03520	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FVF64_RS03540	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FVF64_RS03560	COG0799	negative regulation of ribosome biogenesis
FVF64_RS03590	COG0406	alpha-ribazole phosphatase activity
FVF64_RS03595	COG0598	Magnesium transport protein CorA
FVF64_RS03625	COG0802	atpase or kinase
FVF64_RS03680	COG0516	GMP reductase activity
FVF64_RS03690	COG1022	Amp-dependent synthetase and ligase
FVF64_RS03720	COG0575	Belongs to the CDS family
FVF64_RS03760	COG1573	uracil-dna glycosylase
FVF64_RS03770	COG0133	tryptophan synthase activity
FVF64_RS03785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FVF64_RS03800	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FVF64_RS03820	COG1716	ATPase activity
FVF64_RS03835	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FVF64_RS03840	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
FVF64_RS03895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FVF64_RS03920	COG0045	succinate-CoA ligase (ADP-forming) activity
FVF64_RS03955	COG0438	transferase activity, transferring glycosyl groups
FVF64_RS03960	COG1560	Kdo2-lipid A biosynthetic process
FVF64_RS03975	COG0488	(ABC) transporter
FVF64_RS03985	COG0456	acetyltransferase
FVF64_RS04055	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
FVF64_RS04065	COG0436	Aminotransferase
FVF64_RS04075	COG0436	Aminotransferase
FVF64_RS04080	COG0561	phosphatase activity
FVF64_RS04085	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FVF64_RS04110	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FVF64_RS04140	COG0488	(ABC) transporter
FVF64_RS04165	COG0450	alkyl hydroperoxide reductase
FVF64_RS04175	COG0583	DNA-binding transcription factor activity
FVF64_RS04215	COG0167	dihydroorotate dehydrogenase activity
FVF64_RS04225	COG0284	orotidine-5'-phosphate decarboxylase activity
FVF64_RS04230	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FVF64_RS04250	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
FVF64_RS04270	COG1119	ATPase activity
FVF64_RS04275	COG0297	glycogen (starch) synthase activity
FVF64_RS04295	COG0067	glutamate synthase
FVF64_RS04295	COG0069	glutamate synthase activity
FVF64_RS04295	COG0070	glutamate synthase
FVF64_RS04315	COG2860	membrane
FVF64_RS04320	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FVF64_RS04345	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FVF64_RS04370	COG1702	phosphate starvation-inducible protein PhoH
FVF64_RS04375	COG0537	adenosine 5'-monophosphoramidase activity
FVF64_RS04380	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FVF64_RS04405	COG2151	metal-sulfur cluster biosynthetic enzyme
FVF64_RS04410	COG0822	iron-sulfur transferase activity
FVF64_RS04420	COG0396	ATPase activity
FVF64_RS04425	COG0719	Fe-S assembly protein
FVF64_RS04435	COG1376	ErfK ybiS ycfS ynhG family protein
FVF64_RS04450	COG1523	belongs to the glycosyl hydrolase 13 family
FVF64_RS04495	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FVF64_RS04540	COG0588	phosphoglycerate mutase activity
FVF64_RS04545	COG1950	PFAM Membrane protein of
FVF64_RS04580	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FVF64_RS04595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FVF64_RS04610	COG1131	(ABC) transporter
FVF64_RS04615	COG1725	Transcriptional regulator
FVF64_RS04625	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
FVF64_RS04650	COG0563	adenylate kinase activity
FVF64_RS04665	COG3039	Transposase
FVF64_RS04685	COG0280	phosphate acetyltransferase
FVF64_RS04685	COG0857	belongs to the CobB CobQ family
FVF64_RS04690	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FVF64_RS04720	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FVF64_RS04735	COG0494	nUDIX hydrolase
FVF64_RS04745	COG0469	pyruvate kinase activity
FVF64_RS04760	COG0237	dephospho-CoA kinase activity
FVF64_RS04765	COG0539	negative regulation of cytoplasmic translation
FVF64_RS04775	COG0803	Belongs to the bacterial solute-binding protein 9 family
FVF64_RS04780	COG1121	(ABC) transporter
FVF64_RS04795	COG1329	Transcriptional regulator
FVF64_RS04805	COG0745	RESPONSE REGULATOR receiver
FVF64_RS04810	COG2205	protein histidine kinase activity
FVF64_RS04840	COG1316	TRANSCRIPTIONal
FVF64_RS04845	COG1316	TRANSCRIPTIONal
FVF64_RS04870	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FVF64_RS04880	COG1760	l-serine dehydratase
FVF64_RS04925	COG1116	anion transmembrane transporter activity
FVF64_RS04950	COG1472	Belongs to the glycosyl hydrolase 3 family
FVF64_RS04960	COG1966	Carbon starvation protein
FVF64_RS05000	COG1918	ferrous iron import across plasma membrane
FVF64_RS05000	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
FVF64_RS05025	COG0363	glucosamine-6-phosphate deaminase activity
FVF64_RS05030	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FVF64_RS05035	COG3340	Belongs to the peptidase S51 family
FVF64_RS05040	COG1114	Component of the transport system for branched-chain amino acids
FVF64_RS05070	COG2233	PERMEase
FVF64_RS05090	COG0012	GTP binding
FVF64_RS05095	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FVF64_RS05105	COG4585	Histidine kinase
FVF64_RS05110	COG2197	response regulator
FVF64_RS05120	COG0577	efflux transmembrane transporter activity
FVF64_RS05120	COG1136	(ABC) transporter
FVF64_RS05130	COG1122	ATPase activity
FVF64_RS05135	COG2873	o-acetylhomoserine
FVF64_RS05165	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
FVF64_RS05230	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FVF64_RS05235	COG1882	Formate acetyltransferase
FVF64_RS05250	COG1473	amidohydrolase
FVF64_RS05255	COG2011	ABC-type metal ion transport system permease component
FVF64_RS05265	COG1464	Belongs to the NlpA lipoprotein family
FVF64_RS05270	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
FVF64_RS05275	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FVF64_RS05300	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FVF64_RS05305	COG4975	Glucose uptake
FVF64_RS05310	COG1201	RNA secondary structure unwinding
FVF64_RS05335	COG0187	DNA topoisomerase II activity
FVF64_RS05340	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FVF64_RS05350	COG0142	geranyltranstransferase activity
FVF64_RS05370	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FVF64_RS05380	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FVF64_RS05405	COG1396	sequence-specific DNA binding
FVF64_RS05415	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FVF64_RS05435	COG2357	RelA SpoT domain protein
FVF64_RS05440	COG0670	Belongs to the BI1 family
FVF64_RS05445	COG3804	dihydrodipicolinate reductase
FVF64_RS05460	COG1131	(ABC) transporter
FVF64_RS05465	COG4585	Histidine kinase
FVF64_RS05470	COG2197	response regulator
FVF64_RS05485	COG0366	Alpha amylase catalytic
FVF64_RS05490	COG2182	Extracellular solute-binding protein
FVF64_RS05505	COG0110	maltose O-acetyltransferase activity
FVF64_RS05515	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
FVF64_RS05545	COG0708	Exodeoxyribonuclease III
FVF64_RS05560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVF64_RS05565	COG0601	transmembrane transport
FVF64_RS05570	COG4166	transmembrane transport
FVF64_RS05580	COG1136	(ABC) transporter
FVF64_RS05585	COG0577	efflux transmembrane transporter activity
FVF64_RS05595	COG0287	Prephenate dehydrogenase
FVF64_RS05610	COG1217	gtp-binding protein TYPA
FVF64_RS05615	COG0477	Major facilitator Superfamily
FVF64_RS05645	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FVF64_RS05660	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FVF64_RS05670	COG2017	converts alpha-aldose to the beta-anomer
FVF64_RS05695	COG0285	dihydrofolate synthase activity
FVF64_RS05715	COG0006	proline dipeptidase activity
FVF64_RS05720	COG2816	NAD+ diphosphatase activity
FVF64_RS05740	COG0582	viral genome integration into host DNA
FVF64_RS05825	COG0601	transmembrane transport
FVF64_RS05865	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FVF64_RS05875	COG0768	penicillin binding
FVF64_RS05900	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FVF64_RS05920	COG1230	cation diffusion facilitator family transporter
FVF64_RS05930	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FVF64_RS05940	COG1643	Atp-dependent helicase
FVF64_RS05985	COG0587	DNA-directed DNA polymerase activity
FVF64_RS06020	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FVF64_RS06070	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FVF64_RS06075	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
FVF64_RS06080	COG1957	nucleoside hydrolase
FVF64_RS06130	COG3480	Lon protease (S16) C-terminal proteolytic domain
FVF64_RS06155	COG0613	PHP domain protein
FVF64_RS06165	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FVF64_RS06190	COG1126	abc transporter atp-binding protein
FVF64_RS06195	COG0765	amino acid transport
FVF64_RS06200	COG0765	amino acid transport
FVF64_RS06205	COG0436	Aminotransferase
FVF64_RS06215	COG2011	ABC-type metal ion transport system permease component
FVF64_RS06225	COG1464	Belongs to the NlpA lipoprotein family
FVF64_RS06230	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
FVF64_RS06295	COG4166	transmembrane transport
FVF64_RS06300	COG2814	Major facilitator Superfamily
FVF64_RS06305	COG1842	Phage shock protein A
FVF64_RS06330	COG2365	Tyrosine phosphatase family
FVF64_RS06345	COG1132	(ABC) transporter
FVF64_RS06350	COG1132	(ABC) transporter
FVF64_RS06405	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
FVF64_RS06410	COG1518	maintenance of DNA repeat elements
FVF64_RS06410	COG1468	defense response to virus
FVF64_RS06445	COG1328	CTP reductase activity
FVF64_RS06445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FVF64_RS06450	COG1570	exodeoxyribonuclease VII activity
FVF64_RS06455	COG1722	exodeoxyribonuclease VII activity
FVF64_RS06475	COG0436	Aminotransferase
FVF64_RS06510	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FVF64_RS06535	COG0210	DNA helicase
FVF64_RS06555	COG0714	Associated with various cellular activities
FVF64_RS06595	COG1194	a g-specific adenine glycosylase
FVF64_RS06600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FVF64_RS06620	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FVF64_RS06630	COG1349	DNA-binding transcription factor activity
FVF64_RS06635	COG1216	Glycosyl transferase, family 2
FVF64_RS06640	COG0167	dihydroorotate dehydrogenase activity
FVF64_RS06645	COG1902	pentaerythritol trinitrate reductase activity
FVF64_RS06650	COG4499	WXG100 protein secretion system (Wss), protein YukC
FVF64_RS06650	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FVF64_RS06660	COG0095	Lipoate-protein ligase
FVF64_RS06705	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
FVF64_RS06740	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
FVF64_RS06750	COG1088	dTDP-glucose 4,6-dehydratase activity
FVF64_RS06770	COG1442	glycosyl transferase family 8
FVF64_RS06770	COG1216	Glycosyl transferase, family 2
FVF64_RS06820	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
FVF64_RS06830	COG2814	Major facilitator Superfamily
FVF64_RS06885	COG4988	ABC transporter
FVF64_RS06900	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FVF64_RS06910	COG0489	protein tyrosine kinase activity
FVF64_RS06930	COG0083	homoserine kinase activity
FVF64_RS06935	COG0460	homoserine dehydrogenase
FVF64_RS06940	COG0019	diaminopimelate decarboxylase activity
FVF64_RS06955	COG0251	oxidation-reduction process
FVF64_RS06960	COG0395	ABC-type sugar transport system, permease component
FVF64_RS06965	COG3459	Glycosyltransferase 36 associated
FVF64_RS06990	COG0545	Peptidyl-prolyl cis-trans isomerase
FVF64_RS07000	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FVF64_RS07035	COG0356	it plays a direct role in the translocation of protons across the membrane
FVF64_RS07045	COG0477	Major facilitator Superfamily
FVF64_RS07100	COG0582	viral genome integration into host DNA
FVF64_RS07120	COG0679	Auxin Efflux Carrier
FVF64_RS07125	COG0028	Belongs to the TPP enzyme family
FVF64_RS07150	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FVF64_RS07160	COG0745	RESPONSE REGULATOR receiver
FVF64_RS07170	COG0747	negative chemotaxis
FVF64_RS07185	COG0287	Prephenate dehydrogenase
FVF64_RS07185	COG1605	Chorismate mutase
FVF64_RS07250	COG2217	Heavy metal translocating P-type atpase
FVF64_RS07260	COG0179	Fumarylacetoacetate (FAA) hydrolase
FVF64_RS07285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FVF64_RS07300	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FVF64_RS07355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVF64_RS07370	COG1609	Transcriptional regulator
FVF64_RS07415	COG1368	sulfuric ester hydrolase activity
FVF64_RS07425	COG1368	sulfuric ester hydrolase activity
FVF64_RS07430	COG1216	Glycosyl transferase, family 2
FVF64_RS07480	COG1216	Glycosyl transferase, family 2
FVF64_RS07535	COG0084	hydrolase, TatD family'
FVF64_RS07550	COG1132	(ABC) transporter
FVF64_RS07555	COG1132	(ABC) transporter
FVF64_RS07595	COG0586	Pfam SNARE associated Golgi protein
FVF64_RS07615	COG1309	transcriptional regulator
FVF64_RS07620	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FVF64_RS07625	COG0789	Transcriptional regulator
FVF64_RS07630	COG0484	heat shock protein binding
FVF64_RS07660	COG1523	belongs to the glycosyl hydrolase 13 family
FVF64_RS07665	COG3833	ABC-type maltose transport systems, permease component
FVF64_RS07670	COG1175	transmembrane transport
FVF64_RS07680	COG0366	Alpha amylase catalytic
FVF64_RS07705	COG1609	Transcriptional regulator
FVF64_RS07715	COG0366	Alpha amylase catalytic
FVF64_RS07730	COG0778	Nitroreductase
FVF64_RS07740	COG2814	Major facilitator Superfamily
FVF64_RS07815	COG1609	Transcriptional regulator
FVF64_RS07820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FVF64_RS07825	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FVF64_RS07830	COG0366	Alpha amylase catalytic
FVF64_RS07850	COG0395	ABC-type sugar transport system, permease component
FVF64_RS07855	COG1175	transmembrane transport
FVF64_RS07875	COG0590	tRNA wobble adenosine to inosine editing
FVF64_RS07875	COG0037	tRNA processing
FVF64_RS07880	COG0025	NhaP-type Na H and K H
FVF64_RS07900	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FVF64_RS07910	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FVF64_RS07920	COG3842	ATPase activity
FVF64_RS07925	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
FVF64_RS07945	COG3583	domain protein
FVF64_RS07965	COG0617	tRNA 3'-terminal CCA addition
FVF64_RS07985	COG0492	ferredoxin-NADP+ reductase activity
FVF64_RS07990	COG1475	DNA binding
FVF64_RS07995	COG1192	Involved in chromosome partitioning
FVF64_RS08005	COG1847	R3H domain protein
FVF64_RS08035	COG0592	DNA-directed DNA polymerase activity
FVF64_RS08050	COG0187	DNA topoisomerase II activity
FVF64_RS08055	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FVF64_RS08070	COG1272	protein, Hemolysin III
FVF64_RS08075	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FVF64_RS08080	COG2814	Major facilitator Superfamily
FVF64_RS08095	COG1970	mechanosensitive ion channel activity
FVF64_RS08140	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FVF64_RS08145	COG2226	methyltransferase
FVF64_RS08250	COG0583	DNA-binding transcription factor activity
FVF64_RS08265	COG3231	kanamycin kinase activity