locus-tag	class	description
BLAC_RS00010	COG0592	DNA-directed DNA polymerase activity
BLAC_RS00025	COG0187	DNA topoisomerase II activity
BLAC_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLAC_RS00045	COG1272	protein, Hemolysin III
BLAC_RS00050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLAC_RS00070	COG1970	mechanosensitive ion channel activity
BLAC_RS00110	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BLAC_RS00115	COG2226	methyltransferase
BLAC_RS00235	COG0783	Belongs to the Dps family
BLAC_RS00240	COG1253	flavin adenine dinucleotide binding
BLAC_RS00245	COG0288	reversible hydration of carbon dioxide
BLAC_RS00250	COG1609	Transcriptional regulator
BLAC_RS00275	COG1609	Transcriptional regulator
BLAC_RS00280	COG3534	alpha-L-arabinofuranosidase
BLAC_RS00300	COG0656	L-ascorbic acid biosynthetic process
BLAC_RS00305	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BLAC_RS00315	COG0180	Tryptophanyl-tRNA synthetase
BLAC_RS00330	COG0058	SHG alpha-glucan phosphorylase activity
BLAC_RS00360	COG3764	Sortase (surface protein transpeptidase)
BLAC_RS00375	COG0515	serine threonine protein kinase
BLAC_RS00380	COG0768	penicillin binding
BLAC_RS00410	COG0697	spore germination
BLAC_RS00425	COG2226	methyltransferase
BLAC_RS00430	COG2261	transglycosylase associated protein
BLAC_RS00435	COG2261	transglycosylase associated protein
BLAC_RS00450	COG2217	Heavy metal translocating P-type atpase
BLAC_RS00470	COG0343	queuine tRNA-ribosyltransferase activity
BLAC_RS00475	COG4974	Belongs to the 'phage' integrase family
BLAC_RS00545	COG2814	Major facilitator Superfamily
BLAC_RS00560	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLAC_RS00590	COG0667	Aldo Keto reductase
BLAC_RS00625	COG1063	alcohol dehydrogenase
BLAC_RS00630	COG0583	DNA-binding transcription factor activity
BLAC_RS00640	COG0191	fructose-bisphosphate aldolase activity
BLAC_RS00650	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLAC_RS00700	COG2211	Major facilitator Superfamily
BLAC_RS00755	COG0477	Major facilitator Superfamily
BLAC_RS00780	COG2182	Extracellular solute-binding protein
BLAC_RS00785	COG2182	Extracellular solute-binding protein
BLAC_RS00790	COG1175	transmembrane transport
BLAC_RS00795	COG0395	ABC-type sugar transport system, permease component
BLAC_RS00805	COG1609	Transcriptional regulator
BLAC_RS00825	COG1132	(ABC) transporter
BLAC_RS00830	COG0390	transport system, permease component
BLAC_RS00835	COG1113	amino acid transport
BLAC_RS00840	COG1136	(ABC) transporter
BLAC_RS00840	COG0577	efflux transmembrane transporter activity
BLAC_RS00850	COG1113	amino acid transport
BLAC_RS00865	COG0577	efflux transmembrane transporter activity
BLAC_RS00870	COG1136	(ABC) transporter
BLAC_RS00870	COG0577	efflux transmembrane transporter activity
BLAC_RS00875	COG1846	Transcriptional regulator
BLAC_RS00895	COG0671	phosphoesterase, PA-phosphatase related
BLAC_RS00900	COG0110	maltose O-acetyltransferase activity
BLAC_RS00940	COG1129	ABC transporter
BLAC_RS00975	COG1309	transcriptional regulator
BLAC_RS00995	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BLAC_RS01005	COG0305	Participates in initiation and elongation during chromosome replication
BLAC_RS01010	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLAC_RS01045	COG0406	alpha-ribazole phosphatase activity
BLAC_RS01045	COG0494	nUDIX hydrolase
BLAC_RS01130	COG1260	myo-inositol-1-phosphate synthase
BLAC_RS01140	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLAC_RS01140	COG1754	DNA topoisomerase type I activity
BLAC_RS01200	COG0406	alpha-ribazole phosphatase activity
BLAC_RS01250	COG0446	pyridine nucleotide-disulphide oxidoreductase
BLAC_RS01255	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLAC_RS01305	COG0436	Aminotransferase
BLAC_RS01320	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BLAC_RS01320	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BLAC_RS01330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLAC_RS01335	COG0742	ribosomal rna small subunit methyltransferase
BLAC_RS01350	COG1837	Belongs to the UPF0109 family
BLAC_RS01390	COG0488	(ABC) transporter
BLAC_RS01400	COG0440	acetolactate synthase activity
BLAC_RS01440	COG0667	Aldo Keto reductase
BLAC_RS01505	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLAC_RS01525	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLAC_RS01530	COG1530	ribonuclease E activity
BLAC_RS01555	COG0436	Aminotransferase
BLAC_RS01590	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BLAC_RS01590	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BLAC_RS01595	COG1268	BioY protein
BLAC_RS01600	COG4770	biotin carboxylase activity
BLAC_RS01605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLAC_RS01610	COG0159	tryptophan synthase activity
BLAC_RS01630	COG0039	L-malate dehydrogenase activity
BLAC_RS01645	COG1704	LemA family
BLAC_RS01655	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLAC_RS01660	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLAC_RS01680	COG0826	peptidase U32
BLAC_RS01695	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BLAC_RS01705	COG3579	cysteine-type endopeptidase activity
BLAC_RS01715	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BLAC_RS01715	COG2755	lipolytic protein G-D-S-L family
BLAC_RS01720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BLAC_RS01725	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLAC_RS01735	COG0745	RESPONSE REGULATOR receiver
BLAC_RS01750	COG0581	inorganic phosphate transmembrane transporter activity
BLAC_RS01770	COG0581	inorganic phosphate transmembrane transporter activity
BLAC_RS01780	COG2252	PERMEase
BLAC_RS01865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BLAC_RS01870	COG0531	amino acid
BLAC_RS01885	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLAC_RS01895	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLAC_RS01900	COG1739	Uncharacterized protein family UPF0029
BLAC_RS01935	COG1012	belongs to the aldehyde dehydrogenase family
BLAC_RS01935	COG1454	alcohol dehydrogenase
BLAC_RS01995	COG0255	Belongs to the universal ribosomal protein uL29 family
BLAC_RS02125	COG0196	riboflavin kinase activity
BLAC_RS02145	COG0328	RNA-DNA hybrid ribonuclease activity
BLAC_RS02160	COG1597	lipid kinase activity
BLAC_RS02160	COG1803	Methylglyoxal synthase
BLAC_RS02185	COG2197	response regulator
BLAC_RS02205	COG0626	cystathionine gamma-synthase activity
BLAC_RS02225	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BLAC_RS02240	COG3579	cysteine-type endopeptidase activity
BLAC_RS02245	COG0531	amino acid
BLAC_RS02255	COG1113	amino acid transport
BLAC_RS02275	COG1063	alcohol dehydrogenase
BLAC_RS02280	COG3321	synthase
BLAC_RS02280	COG0604	alcohol dehydrogenase
BLAC_RS02280	COG1028	Short-chain dehydrogenase reductase Sdr
BLAC_RS02290	COG5002	protein histidine kinase activity
BLAC_RS02295	COG0704	Plays a role in the regulation of phosphate uptake
BLAC_RS02300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BLAC_RS02305	COG1705	Flagellar rod assembly protein muramidase FlgJ
BLAC_RS02305	COG3942	CHAP domain
BLAC_RS02310	COG0791	NLP P60 protein
BLAC_RS02310	COG1388	LysM domain
BLAC_RS02330	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BLAC_RS02335	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLAC_RS02415	COG3189	MarR family transcriptional regulator
BLAC_RS02430	COG1609	Transcriptional regulator
BLAC_RS02465	COG0395	ABC-type sugar transport system, permease component
BLAC_RS02495	COG1216	Glycosyl transferase, family 2
BLAC_RS02500	COG0628	permease
BLAC_RS02535	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLAC_RS02550	COG1946	Acyl-CoA thioesterase
BLAC_RS02560	COG0242	peptide deformylase activity
BLAC_RS02565	COG2873	o-acetylhomoserine
BLAC_RS02600	COG3507	Belongs to the glycosyl hydrolase 43 family
BLAC_RS02605	COG1609	Transcriptional regulator
BLAC_RS02615	COG1175	transmembrane transport
BLAC_RS02625	COG3507	Belongs to the glycosyl hydrolase 43 family
BLAC_RS02635	COG2272	Belongs to the type-B carboxylesterase lipase family
BLAC_RS02645	COG1070	Carbohydrate kinase
BLAC_RS02650	COG1940	carbohydrate kinase activity
BLAC_RS02670	COG0009	L-threonylcarbamoyladenylate synthase
BLAC_RS02690	COG0561	phosphatase activity
BLAC_RS02695	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLAC_RS02715	COG3590	peptidase
BLAC_RS02730	COG0372	Belongs to the citrate synthase family
BLAC_RS02745	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLAC_RS02750	COG2884	Cell division ATP-binding protein ftsE
BLAC_RS02760	COG1388	LysM domain
BLAC_RS02760	COG3942	CHAP domain
BLAC_RS02775	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLAC_RS02780	COG0765	amino acid transport
BLAC_RS02795	COG0784	Response regulator, receiver
BLAC_RS02795	COG2205	protein histidine kinase activity
BLAC_RS02795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLAC_RS02795	COG2198	Histidine kinase
BLAC_RS02825	COG0601	transmembrane transport
BLAC_RS02830	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLAC_RS02840	COG4172	Belongs to the ABC transporter superfamily
BLAC_RS02890	COG0454	-acetyltransferase
BLAC_RS02935	COG0371	Dehydrogenase
BLAC_RS02950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLAC_RS02955	COG0358	DNA primase activity
BLAC_RS02960	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BLAC_RS02970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BLAC_RS02975	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BLAC_RS02980	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BLAC_RS02985	COG0735	belongs to the Fur family
BLAC_RS02990	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BLAC_RS02995	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BLAC_RS03000	COG0151	Belongs to the GarS family
BLAC_RS03015	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLAC_RS03070	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLAC_RS03150	COG0284	orotidine-5'-phosphate decarboxylase activity
BLAC_RS03175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BLAC_RS03190	COG0560	Phosphoserine phosphatase
BLAC_RS03195	COG0586	Pfam SNARE associated Golgi protein
BLAC_RS03205	COG4122	O-methyltransferase activity
BLAC_RS03235	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLAC_RS03275	COG0714	Associated with various cellular activities
BLAC_RS03290	COG1278	Cold shock
BLAC_RS03310	COG0745	RESPONSE REGULATOR receiver
BLAC_RS03315	COG2205	protein histidine kinase activity
BLAC_RS03320	COG1278	Cold shock
BLAC_RS03355	COG1196	nuclear chromosome segregation
BLAC_RS03365	COG1126	abc transporter atp-binding protein
BLAC_RS03370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLAC_RS03375	COG0765	amino acid transport
BLAC_RS03380	COG0765	amino acid transport
BLAC_RS03385	COG2326	polyphosphate kinase activity
BLAC_RS03400	COG2814	Major facilitator Superfamily
BLAC_RS03405	COG1022	Amp-dependent synthetase and ligase
BLAC_RS03410	COG3328	transposase activity
BLAC_RS03435	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BLAC_RS03445	COG0656	L-ascorbic acid biosynthetic process
BLAC_RS03470	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BLAC_RS03490	COG2151	metal-sulfur cluster biosynthetic enzyme
BLAC_RS03490	COG0489	protein tyrosine kinase activity
BLAC_RS03495	COG4721	ABC-type cobalt transport system, permease component
BLAC_RS03575	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLAC_RS03600	COG1136	(ABC) transporter
BLAC_RS03605	COG4721	ABC-type cobalt transport system, permease component
BLAC_RS03610	COG4172	Belongs to the ABC transporter superfamily
BLAC_RS03615	COG1136	(ABC) transporter
BLAC_RS03630	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLAC_RS03720	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLAC_RS03725	COG0569	domain protein
BLAC_RS03740	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLAC_RS03760	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLAC_RS03780	COG0799	negative regulation of ribosome biogenesis
BLAC_RS03810	COG0406	alpha-ribazole phosphatase activity
BLAC_RS03815	COG0598	Magnesium transport protein CorA
BLAC_RS03845	COG0802	atpase or kinase
BLAC_RS03900	COG0516	GMP reductase activity
BLAC_RS03910	COG1022	Amp-dependent synthetase and ligase
BLAC_RS03940	COG0575	Belongs to the CDS family
BLAC_RS03980	COG1573	uracil-dna glycosylase
BLAC_RS04005	COG0133	tryptophan synthase activity
BLAC_RS04020	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BLAC_RS04035	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLAC_RS04055	COG1716	ATPase activity
BLAC_RS04070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLAC_RS04075	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLAC_RS04150	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLAC_RS04170	COG0045	succinate-CoA ligase (ADP-forming) activity
BLAC_RS04205	COG0438	transferase activity, transferring glycosyl groups
BLAC_RS04210	COG1560	Kdo2-lipid A biosynthetic process
BLAC_RS04225	COG0488	(ABC) transporter
BLAC_RS04235	COG0456	acetyltransferase
BLAC_RS04305	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BLAC_RS04315	COG0436	Aminotransferase
BLAC_RS04325	COG0436	Aminotransferase
BLAC_RS04330	COG0561	phosphatase activity
BLAC_RS04335	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLAC_RS04360	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BLAC_RS04390	COG0488	(ABC) transporter
BLAC_RS04415	COG0450	alkyl hydroperoxide reductase
BLAC_RS04425	COG0583	DNA-binding transcription factor activity
BLAC_RS04465	COG0167	dihydroorotate dehydrogenase activity
BLAC_RS04475	COG0284	orotidine-5'-phosphate decarboxylase activity
BLAC_RS04480	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLAC_RS04505	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BLAC_RS04525	COG1119	ATPase activity
BLAC_RS04530	COG0297	glycogen (starch) synthase activity
BLAC_RS04550	COG0067	glutamate synthase
BLAC_RS04550	COG0069	glutamate synthase activity
BLAC_RS04550	COG0070	glutamate synthase
BLAC_RS04570	COG2860	membrane
BLAC_RS04575	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLAC_RS04600	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BLAC_RS04625	COG1702	phosphate starvation-inducible protein PhoH
BLAC_RS04630	COG0537	adenosine 5'-monophosphoramidase activity
BLAC_RS04635	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BLAC_RS04660	COG2151	metal-sulfur cluster biosynthetic enzyme
BLAC_RS04665	COG0822	iron-sulfur transferase activity
BLAC_RS04675	COG0396	ATPase activity
BLAC_RS04680	COG0719	Fe-S assembly protein
BLAC_RS04690	COG1376	ErfK ybiS ycfS ynhG family protein
BLAC_RS04765	COG0588	phosphoglycerate mutase activity
BLAC_RS04770	COG1950	PFAM Membrane protein of
BLAC_RS04805	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BLAC_RS04820	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BLAC_RS04840	COG1725	Transcriptional regulator
BLAC_RS04850	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BLAC_RS04875	COG0563	adenylate kinase activity
BLAC_RS04910	COG0280	phosphate acetyltransferase
BLAC_RS04910	COG0857	belongs to the CobB CobQ family
BLAC_RS04915	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLAC_RS04945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLAC_RS04960	COG0494	nUDIX hydrolase
BLAC_RS04970	COG0469	pyruvate kinase activity
BLAC_RS04990	COG0539	negative regulation of cytoplasmic translation
BLAC_RS05000	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLAC_RS05005	COG1121	(ABC) transporter
BLAC_RS05020	COG1329	Transcriptional regulator
BLAC_RS05030	COG0745	RESPONSE REGULATOR receiver
BLAC_RS05035	COG2205	protein histidine kinase activity
BLAC_RS05065	COG1316	TRANSCRIPTIONal
BLAC_RS05070	COG1316	TRANSCRIPTIONal
BLAC_RS05095	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLAC_RS05105	COG1760	l-serine dehydratase
BLAC_RS05150	COG1116	anion transmembrane transporter activity
BLAC_RS05175	COG1472	Belongs to the glycosyl hydrolase 3 family
BLAC_RS05185	COG1966	Carbon starvation protein
BLAC_RS05190	COG1132	(ABC) transporter
BLAC_RS05195	COG1132	(ABC) transporter
BLAC_RS05230	COG1918	ferrous iron import across plasma membrane
BLAC_RS05230	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BLAC_RS05255	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BLAC_RS05260	COG3340	Belongs to the peptidase S51 family
BLAC_RS05265	COG1114	Component of the transport system for branched-chain amino acids
BLAC_RS05295	COG2233	PERMEase
BLAC_RS05315	COG0012	GTP binding
BLAC_RS05320	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLAC_RS05330	COG4585	Histidine kinase
BLAC_RS05335	COG2197	response regulator
BLAC_RS05345	COG0577	efflux transmembrane transporter activity
BLAC_RS05345	COG1136	(ABC) transporter
BLAC_RS05355	COG1122	ATPase activity
BLAC_RS05360	COG2873	o-acetylhomoserine
BLAC_RS05390	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BLAC_RS05455	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BLAC_RS05460	COG1882	Formate acetyltransferase
BLAC_RS05475	COG1473	amidohydrolase
BLAC_RS05480	COG2011	ABC-type metal ion transport system permease component
BLAC_RS05490	COG1464	Belongs to the NlpA lipoprotein family
BLAC_RS05500	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BLAC_RS05525	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLAC_RS05530	COG4975	Glucose uptake
BLAC_RS05535	COG1201	RNA secondary structure unwinding
BLAC_RS05560	COG0187	DNA topoisomerase II activity
BLAC_RS05565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLAC_RS05575	COG0142	geranyltranstransferase activity
BLAC_RS05595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLAC_RS05605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLAC_RS05625	COG1396	sequence-specific DNA binding
BLAC_RS05635	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLAC_RS05655	COG2357	RelA SpoT domain protein
BLAC_RS05660	COG0670	Belongs to the BI1 family
BLAC_RS05665	COG3804	dihydrodipicolinate reductase
BLAC_RS05680	COG1131	(ABC) transporter
BLAC_RS05690	COG2197	response regulator
BLAC_RS05710	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BLAC_RS05800	COG0708	Exodeoxyribonuclease III
BLAC_RS05820	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLAC_RS05825	COG0601	transmembrane transport
BLAC_RS05830	COG4166	transmembrane transport
BLAC_RS05840	COG1136	(ABC) transporter
BLAC_RS05845	COG0577	efflux transmembrane transporter activity
BLAC_RS05855	COG0287	Prephenate dehydrogenase
BLAC_RS05870	COG1217	gtp-binding protein TYPA
BLAC_RS05875	COG0477	Major facilitator Superfamily
BLAC_RS05905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLAC_RS05920	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BLAC_RS05930	COG2017	converts alpha-aldose to the beta-anomer
BLAC_RS05955	COG0285	dihydrofolate synthase activity
BLAC_RS05975	COG0006	proline dipeptidase activity
BLAC_RS05980	COG2816	NAD+ diphosphatase activity
BLAC_RS06010	COG0601	transmembrane transport
BLAC_RS06050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLAC_RS06085	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLAC_RS06105	COG1230	cation diffusion facilitator family transporter
BLAC_RS06115	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BLAC_RS06125	COG1643	Atp-dependent helicase
BLAC_RS06170	COG0587	DNA-directed DNA polymerase activity
BLAC_RS06205	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLAC_RS06210	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BLAC_RS06250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLAC_RS06255	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BLAC_RS06260	COG1957	nucleoside hydrolase
BLAC_RS06315	COG3480	Lon protease (S16) C-terminal proteolytic domain
BLAC_RS06340	COG0613	PHP domain protein
BLAC_RS06350	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BLAC_RS06375	COG1126	abc transporter atp-binding protein
BLAC_RS06385	COG0765	amino acid transport
BLAC_RS06390	COG0436	Aminotransferase
BLAC_RS06395	COG2011	ABC-type metal ion transport system permease component
BLAC_RS06405	COG1464	Belongs to the NlpA lipoprotein family
BLAC_RS06410	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BLAC_RS06465	COG4166	transmembrane transport
BLAC_RS06470	COG2814	Major facilitator Superfamily
BLAC_RS06475	COG1842	Phage shock protein A
BLAC_RS06520	COG1132	(ABC) transporter
BLAC_RS06525	COG1132	(ABC) transporter
BLAC_RS06580	COG1328	CTP reductase activity
BLAC_RS06580	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLAC_RS06585	COG1570	exodeoxyribonuclease VII activity
BLAC_RS06590	COG1722	exodeoxyribonuclease VII activity
BLAC_RS06610	COG0436	Aminotransferase
BLAC_RS06645	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLAC_RS06670	COG0210	DNA helicase
BLAC_RS06690	COG0714	Associated with various cellular activities
BLAC_RS06730	COG1194	a g-specific adenine glycosylase
BLAC_RS06735	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BLAC_RS06755	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BLAC_RS06765	COG1349	DNA-binding transcription factor activity
BLAC_RS06770	COG1216	Glycosyl transferase, family 2
BLAC_RS06775	COG0167	dihydroorotate dehydrogenase activity
BLAC_RS06780	COG1902	pentaerythritol trinitrate reductase activity
BLAC_RS06785	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLAC_RS06785	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLAC_RS06795	COG0095	Lipoate-protein ligase
BLAC_RS06840	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLAC_RS06870	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
BLAC_RS06880	COG1088	dTDP-glucose 4,6-dehydratase activity
BLAC_RS06900	COG1216	Glycosyl transferase, family 2
BLAC_RS06900	COG1442	glycosyl transferase family 8
BLAC_RS06935	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BLAC_RS06945	COG2814	Major facilitator Superfamily
BLAC_RS06985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLAC_RS06995	COG0489	protein tyrosine kinase activity
BLAC_RS07005	COG2801	Transposase and inactivated derivatives
BLAC_RS07015	COG1192	Involved in chromosome partitioning
BLAC_RS07045	COG2826	transposase and inactivated derivatives, IS30 family
BLAC_RS07060	COG0438	transferase activity, transferring glycosyl groups
BLAC_RS07080	COG2801	Transposase and inactivated derivatives
BLAC_RS07105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BLAC_RS07125	COG1857	crispr-associated protein
BLAC_RS07150	COG0083	homoserine kinase activity
BLAC_RS07155	COG0460	homoserine dehydrogenase
BLAC_RS07160	COG0019	diaminopimelate decarboxylase activity
BLAC_RS07175	COG0251	oxidation-reduction process
BLAC_RS07180	COG0395	ABC-type sugar transport system, permease component
BLAC_RS07185	COG3459	Glycosyltransferase 36 associated
BLAC_RS07210	COG0545	Peptidyl-prolyl cis-trans isomerase
BLAC_RS07220	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BLAC_RS07255	COG0356	it plays a direct role in the translocation of protons across the membrane
BLAC_RS07265	COG0477	Major facilitator Superfamily
BLAC_RS07290	COG0679	Auxin Efflux Carrier
BLAC_RS07295	COG0028	Belongs to the TPP enzyme family
BLAC_RS07320	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BLAC_RS07330	COG0745	RESPONSE REGULATOR receiver
BLAC_RS07340	COG0747	negative chemotaxis
BLAC_RS07355	COG1605	Chorismate mutase
BLAC_RS07355	COG0287	Prephenate dehydrogenase
BLAC_RS07420	COG2217	Heavy metal translocating P-type atpase
BLAC_RS07430	COG0179	Fumarylacetoacetate (FAA) hydrolase
BLAC_RS07455	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BLAC_RS07470	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLAC_RS07520	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLAC_RS07570	COG1368	sulfuric ester hydrolase activity
BLAC_RS07575	COG1368	sulfuric ester hydrolase activity
BLAC_RS07580	COG1216	Glycosyl transferase, family 2
BLAC_RS07605	COG1216	Glycosyl transferase, family 2
BLAC_RS07655	COG0084	hydrolase, TatD family'
BLAC_RS07670	COG1132	(ABC) transporter
BLAC_RS07675	COG1132	(ABC) transporter
BLAC_RS07710	COG0586	Pfam SNARE associated Golgi protein
BLAC_RS07730	COG1309	transcriptional regulator
BLAC_RS07735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLAC_RS07740	COG0789	Transcriptional regulator
BLAC_RS07745	COG0484	heat shock protein binding
BLAC_RS07775	COG1523	belongs to the glycosyl hydrolase 13 family
BLAC_RS07780	COG3833	ABC-type maltose transport systems, permease component
BLAC_RS07785	COG1175	transmembrane transport
BLAC_RS07795	COG0366	Alpha amylase catalytic
BLAC_RS07820	COG1609	Transcriptional regulator
BLAC_RS07825	COG2182	Extracellular solute-binding protein
BLAC_RS07830	COG0366	Alpha amylase catalytic
BLAC_RS07845	COG0778	Nitroreductase
BLAC_RS07915	COG1609	Transcriptional regulator
BLAC_RS07920	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BLAC_RS07925	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BLAC_RS07930	COG0366	Alpha amylase catalytic
BLAC_RS07945	COG0395	ABC-type sugar transport system, permease component
BLAC_RS07950	COG1175	transmembrane transport
BLAC_RS07970	COG0590	tRNA wobble adenosine to inosine editing
BLAC_RS07970	COG0037	tRNA processing
BLAC_RS07975	COG0025	NhaP-type Na H and K H
BLAC_RS08000	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLAC_RS08005	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLAC_RS08015	COG3842	ATPase activity
BLAC_RS08020	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BLAC_RS08040	COG3583	domain protein
BLAC_RS08060	COG0617	tRNA 3'-terminal CCA addition
BLAC_RS08080	COG0492	ferredoxin-NADP+ reductase activity
BLAC_RS08085	COG1475	DNA binding
BLAC_RS08090	COG1192	Involved in chromosome partitioning
BLAC_RS08100	COG1847	R3H domain protein