locus-tag	class	description
CJD49_RS00010	COG1957	nucleoside hydrolase
CJD49_RS00065	COG3480	Lon protease (S16) C-terminal proteolytic domain
CJD49_RS00090	COG0613	PHP domain protein
CJD49_RS00100	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJD49_RS00125	COG1126	abc transporter atp-binding protein
CJD49_RS00130	COG0765	amino acid transport
CJD49_RS00135	COG0765	amino acid transport
CJD49_RS00140	COG0436	Aminotransferase
CJD49_RS00150	COG2011	ABC-type metal ion transport system permease component
CJD49_RS00160	COG1464	Belongs to the NlpA lipoprotein family
CJD49_RS00165	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
CJD49_RS00230	COG4166	transmembrane transport
CJD49_RS00235	COG2814	Major facilitator Superfamily
CJD49_RS00240	COG1842	Phage shock protein A
CJD49_RS00260	COG2365	Tyrosine phosphatase family
CJD49_RS00275	COG1132	(ABC) transporter
CJD49_RS00280	COG1132	(ABC) transporter
CJD49_RS00335	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
CJD49_RS00340	COG1518	maintenance of DNA repeat elements
CJD49_RS00340	COG1468	defense response to virus
CJD49_RS00375	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJD49_RS00375	COG1328	CTP reductase activity
CJD49_RS00380	COG1570	exodeoxyribonuclease VII activity
CJD49_RS00385	COG1722	exodeoxyribonuclease VII activity
CJD49_RS00405	COG0436	Aminotransferase
CJD49_RS00440	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CJD49_RS00465	COG0210	DNA helicase
CJD49_RS00485	COG0714	Associated with various cellular activities
CJD49_RS00525	COG1194	a g-specific adenine glycosylase
CJD49_RS00530	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CJD49_RS00550	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CJD49_RS00560	COG1349	DNA-binding transcription factor activity
CJD49_RS00565	COG1216	Glycosyl transferase, family 2
CJD49_RS00570	COG0167	dihydroorotate dehydrogenase activity
CJD49_RS00575	COG1902	pentaerythritol trinitrate reductase activity
CJD49_RS00580	COG4499	WXG100 protein secretion system (Wss), protein YukC
CJD49_RS00580	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJD49_RS00590	COG0095	Lipoate-protein ligase
CJD49_RS00635	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJD49_RS00670	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
CJD49_RS00680	COG1088	dTDP-glucose 4,6-dehydratase activity
CJD49_RS00700	COG1216	Glycosyl transferase, family 2
CJD49_RS00700	COG1442	glycosyl transferase family 8
CJD49_RS00750	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
CJD49_RS00760	COG2814	Major facilitator Superfamily
CJD49_RS00815	COG4988	ABC transporter
CJD49_RS00830	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJD49_RS00840	COG0489	protein tyrosine kinase activity
CJD49_RS00860	COG0083	homoserine kinase activity
CJD49_RS00865	COG0460	homoserine dehydrogenase
CJD49_RS00870	COG0019	diaminopimelate decarboxylase activity
CJD49_RS00885	COG0251	oxidation-reduction process
CJD49_RS00890	COG0395	ABC-type sugar transport system, permease component
CJD49_RS00895	COG3459	Glycosyltransferase 36 associated
CJD49_RS00920	COG0545	Peptidyl-prolyl cis-trans isomerase
CJD49_RS00930	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJD49_RS00965	COG0356	it plays a direct role in the translocation of protons across the membrane
CJD49_RS00975	COG0477	Major facilitator Superfamily
CJD49_RS01050	COG0679	Auxin Efflux Carrier
CJD49_RS01055	COG0028	Belongs to the TPP enzyme family
CJD49_RS01080	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJD49_RS01090	COG0745	RESPONSE REGULATOR receiver
CJD49_RS01100	COG0747	negative chemotaxis
CJD49_RS01115	COG1605	Chorismate mutase
CJD49_RS01115	COG0287	Prephenate dehydrogenase
CJD49_RS01180	COG2217	Heavy metal translocating P-type atpase
CJD49_RS01190	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJD49_RS01215	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CJD49_RS01230	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJD49_RS01285	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CJD49_RS01300	COG1609	Transcriptional regulator
CJD49_RS01345	COG1368	sulfuric ester hydrolase activity
CJD49_RS01355	COG1368	sulfuric ester hydrolase activity
CJD49_RS01360	COG1216	Glycosyl transferase, family 2
CJD49_RS01410	COG1216	Glycosyl transferase, family 2
CJD49_RS01465	COG0084	hydrolase, TatD family'
CJD49_RS01480	COG1132	(ABC) transporter
CJD49_RS01485	COG1132	(ABC) transporter
CJD49_RS01545	COG1309	transcriptional regulator
CJD49_RS01550	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJD49_RS01555	COG0789	Transcriptional regulator
CJD49_RS01560	COG0484	heat shock protein binding
CJD49_RS01590	COG1523	belongs to the glycosyl hydrolase 13 family
CJD49_RS01595	COG3833	ABC-type maltose transport systems, permease component
CJD49_RS01600	COG1175	transmembrane transport
CJD49_RS01610	COG0366	Alpha amylase catalytic
CJD49_RS01635	COG1609	Transcriptional regulator
CJD49_RS01645	COG0366	Alpha amylase catalytic
CJD49_RS01660	COG0778	Nitroreductase
CJD49_RS01670	COG2814	Major facilitator Superfamily
CJD49_RS01745	COG1609	Transcriptional regulator
CJD49_RS01750	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CJD49_RS01755	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJD49_RS01760	COG0366	Alpha amylase catalytic
CJD49_RS01780	COG0395	ABC-type sugar transport system, permease component
CJD49_RS01785	COG1175	transmembrane transport
CJD49_RS01805	COG0590	tRNA wobble adenosine to inosine editing
CJD49_RS01805	COG0037	tRNA processing
CJD49_RS01810	COG0025	NhaP-type Na H and K H
CJD49_RS01830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CJD49_RS01840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJD49_RS01850	COG3842	ATPase activity
CJD49_RS01855	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
CJD49_RS01875	COG3583	domain protein
CJD49_RS01895	COG0617	tRNA 3'-terminal CCA addition
CJD49_RS01915	COG0492	ferredoxin-NADP+ reductase activity
CJD49_RS01920	COG1475	DNA binding
CJD49_RS01925	COG1192	Involved in chromosome partitioning
CJD49_RS01935	COG1847	R3H domain protein
CJD49_RS01965	COG0592	DNA-directed DNA polymerase activity
CJD49_RS01980	COG0187	DNA topoisomerase II activity
CJD49_RS01985	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJD49_RS02000	COG1272	protein, Hemolysin III
CJD49_RS02005	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CJD49_RS02010	COG2814	Major facilitator Superfamily
CJD49_RS02025	COG1970	mechanosensitive ion channel activity
CJD49_RS02070	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJD49_RS02075	COG2226	methyltransferase
CJD49_RS02180	COG0583	DNA-binding transcription factor activity
CJD49_RS02195	COG3231	kanamycin kinase activity
CJD49_RS02235	COG0783	Belongs to the Dps family
CJD49_RS02240	COG1253	flavin adenine dinucleotide binding
CJD49_RS02245	COG0288	reversible hydration of carbon dioxide
CJD49_RS02250	COG1609	Transcriptional regulator
CJD49_RS02270	COG1609	Transcriptional regulator
CJD49_RS02295	COG0656	L-ascorbic acid biosynthetic process
CJD49_RS02300	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CJD49_RS02315	COG0180	Tryptophanyl-tRNA synthetase
CJD49_RS02330	COG0058	SHG alpha-glucan phosphorylase activity
CJD49_RS02370	COG3764	Sortase (surface protein transpeptidase)
CJD49_RS02385	COG0515	serine threonine protein kinase
CJD49_RS02390	COG0768	penicillin binding
CJD49_RS02425	COG0697	spore germination
CJD49_RS02440	COG2226	methyltransferase
CJD49_RS02450	COG2261	transglycosylase associated protein
CJD49_RS02455	COG2261	transglycosylase associated protein
CJD49_RS02480	COG2217	Heavy metal translocating P-type atpase
CJD49_RS02485	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
CJD49_RS02500	COG0343	queuine tRNA-ribosyltransferase activity
CJD49_RS02525	COG2814	Major facilitator Superfamily
CJD49_RS02540	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CJD49_RS02570	COG0667	Aldo Keto reductase
CJD49_RS02610	COG1063	alcohol dehydrogenase
CJD49_RS02615	COG0583	DNA-binding transcription factor activity
CJD49_RS02625	COG0191	fructose-bisphosphate aldolase activity
CJD49_RS02635	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJD49_RS02685	COG2211	Major facilitator Superfamily
CJD49_RS02725	COG0477	Major facilitator Superfamily
CJD49_RS02785	COG1132	(ABC) transporter
CJD49_RS02790	COG0390	transport system, permease component
CJD49_RS02795	COG1113	amino acid transport
CJD49_RS02800	COG1136	(ABC) transporter
CJD49_RS02800	COG0577	efflux transmembrane transporter activity
CJD49_RS02810	COG1113	amino acid transport
CJD49_RS02825	COG0577	efflux transmembrane transporter activity
CJD49_RS02830	COG1136	(ABC) transporter
CJD49_RS02830	COG0577	efflux transmembrane transporter activity
CJD49_RS02840	COG1846	Transcriptional regulator
CJD49_RS02860	COG0671	phosphoesterase, PA-phosphatase related
CJD49_RS02865	COG0110	maltose O-acetyltransferase activity
CJD49_RS02910	COG1129	ABC transporter
CJD49_RS02945	COG1309	transcriptional regulator
CJD49_RS02965	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CJD49_RS02975	COG0305	Participates in initiation and elongation during chromosome replication
CJD49_RS02980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJD49_RS03015	COG0494	nUDIX hydrolase
CJD49_RS03015	COG0406	alpha-ribazole phosphatase activity
CJD49_RS03110	COG1260	myo-inositol-1-phosphate synthase
CJD49_RS03125	COG1754	DNA topoisomerase type I activity
CJD49_RS03125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJD49_RS03190	COG0406	alpha-ribazole phosphatase activity
CJD49_RS03250	COG0446	pyridine nucleotide-disulphide oxidoreductase
CJD49_RS03260	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJD49_RS03315	COG0436	Aminotransferase
CJD49_RS03330	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CJD49_RS03330	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CJD49_RS03340	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
CJD49_RS03355	COG0742	ribosomal rna small subunit methyltransferase
CJD49_RS03370	COG1837	Belongs to the UPF0109 family
CJD49_RS03410	COG0488	(ABC) transporter
CJD49_RS03420	COG0440	acetolactate synthase activity
CJD49_RS03460	COG0667	Aldo Keto reductase
CJD49_RS03530	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJD49_RS03550	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJD49_RS03555	COG1530	ribonuclease E activity
CJD49_RS03595	COG0436	Aminotransferase
CJD49_RS03630	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CJD49_RS03630	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CJD49_RS03635	COG1268	BioY protein
CJD49_RS03640	COG4770	biotin carboxylase activity
CJD49_RS03645	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJD49_RS03670	COG0039	L-malate dehydrogenase activity
CJD49_RS03685	COG1704	LemA family
CJD49_RS03695	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJD49_RS03720	COG0826	peptidase U32
CJD49_RS03740	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJD49_RS03750	COG3579	cysteine-type endopeptidase activity
CJD49_RS03755	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CJD49_RS03760	COG2755	lipolytic protein G-D-S-L family
CJD49_RS03760	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CJD49_RS03765	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CJD49_RS03795	COG0581	inorganic phosphate transmembrane transporter activity
CJD49_RS03805	COG2252	PERMEase
CJD49_RS03890	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJD49_RS03895	COG0531	amino acid
CJD49_RS03910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJD49_RS03920	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
CJD49_RS03925	COG1739	Uncharacterized protein family UPF0029
CJD49_RS04020	COG0255	Belongs to the universal ribosomal protein uL29 family
CJD49_RS04155	COG0196	riboflavin kinase activity
CJD49_RS04180	COG0328	RNA-DNA hybrid ribonuclease activity
CJD49_RS04200	COG1597	lipid kinase activity
CJD49_RS04200	COG1803	Methylglyoxal synthase
CJD49_RS04225	COG2197	response regulator
CJD49_RS04245	COG0626	cystathionine gamma-synthase activity
CJD49_RS04255	COG2873	o-acetylhomoserine
CJD49_RS04265	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJD49_RS04280	COG3579	cysteine-type endopeptidase activity
CJD49_RS04285	COG0531	amino acid
CJD49_RS04295	COG1113	amino acid transport
CJD49_RS04310	COG4716	Myosin-crossreactive antigen
CJD49_RS04315	COG1063	alcohol dehydrogenase
CJD49_RS04320	COG3321	synthase
CJD49_RS04320	COG0604	alcohol dehydrogenase
CJD49_RS04320	COG1028	Short-chain dehydrogenase reductase Sdr
CJD49_RS04330	COG5002	protein histidine kinase activity
CJD49_RS04335	COG0704	Plays a role in the regulation of phosphate uptake
CJD49_RS04340	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJD49_RS04345	COG3942	CHAP domain
CJD49_RS04345	COG1705	Flagellar rod assembly protein muramidase FlgJ
CJD49_RS04350	COG0791	NLP P60 protein
CJD49_RS04350	COG1388	LysM domain
CJD49_RS04370	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJD49_RS04375	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CJD49_RS04380	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJD49_RS04460	COG3189	MarR family transcriptional regulator
CJD49_RS04470	COG3250	beta-galactosidase activity
CJD49_RS04475	COG1609	Transcriptional regulator
CJD49_RS04510	COG0395	ABC-type sugar transport system, permease component
CJD49_RS04540	COG1216	Glycosyl transferase, family 2
CJD49_RS04545	COG0628	permease
CJD49_RS04580	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJD49_RS04595	COG1946	Acyl-CoA thioesterase
CJD49_RS04605	COG0242	peptide deformylase activity
CJD49_RS04610	COG2873	o-acetylhomoserine
CJD49_RS04645	COG3507	Belongs to the glycosyl hydrolase 43 family
CJD49_RS04660	COG1175	transmembrane transport
CJD49_RS04670	COG3507	Belongs to the glycosyl hydrolase 43 family
CJD49_RS04680	COG2272	Belongs to the type-B carboxylesterase lipase family
CJD49_RS04690	COG1070	Carbohydrate kinase
CJD49_RS04695	COG1940	carbohydrate kinase activity
CJD49_RS04715	COG0009	L-threonylcarbamoyladenylate synthase
CJD49_RS04735	COG0561	phosphatase activity
CJD49_RS04740	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJD49_RS04760	COG3590	peptidase
CJD49_RS04770	COG0024	Methionine aminopeptidase
CJD49_RS04775	COG0372	Belongs to the citrate synthase family
CJD49_RS04795	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CJD49_RS04800	COG2884	Cell division ATP-binding protein ftsE
CJD49_RS04810	COG1388	LysM domain
CJD49_RS04810	COG3942	CHAP domain
CJD49_RS04830	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJD49_RS04835	COG0765	amino acid transport
CJD49_RS04850	COG2198	Histidine kinase
CJD49_RS04850	COG2205	protein histidine kinase activity
CJD49_RS04850	COG0784	Response regulator, receiver
CJD49_RS04850	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJD49_RS04855	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJD49_RS04875	COG0747	negative chemotaxis
CJD49_RS04880	COG0601	transmembrane transport
CJD49_RS04885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJD49_RS04895	COG4172	Belongs to the ABC transporter superfamily
CJD49_RS04910	COG0514	ATP-dependent DNA helicase (RecQ)
CJD49_RS04990	COG0371	Dehydrogenase
CJD49_RS05005	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJD49_RS05010	COG0358	DNA primase activity
CJD49_RS05015	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CJD49_RS05025	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJD49_RS05030	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJD49_RS05035	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJD49_RS05040	COG0735	belongs to the Fur family
CJD49_RS05045	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CJD49_RS05050	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CJD49_RS05055	COG0151	Belongs to the GarS family
CJD49_RS05070	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJD49_RS05125	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJD49_RS05205	COG0284	orotidine-5'-phosphate decarboxylase activity
CJD49_RS05230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJD49_RS05245	COG0560	Phosphoserine phosphatase
CJD49_RS05250	COG0586	Pfam SNARE associated Golgi protein
CJD49_RS05260	COG4122	O-methyltransferase activity
CJD49_RS05290	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CJD49_RS05330	COG0714	Associated with various cellular activities
CJD49_RS05345	COG1278	Cold shock
CJD49_RS05365	COG0745	RESPONSE REGULATOR receiver
CJD49_RS05370	COG2205	protein histidine kinase activity
CJD49_RS05375	COG1278	Cold shock
CJD49_RS05410	COG1196	nuclear chromosome segregation
CJD49_RS05420	COG1126	abc transporter atp-binding protein
CJD49_RS05425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJD49_RS05430	COG0765	amino acid transport
CJD49_RS05435	COG0765	amino acid transport
CJD49_RS05440	COG2326	polyphosphate kinase activity
CJD49_RS05455	COG2814	Major facilitator Superfamily
CJD49_RS05460	COG1022	Amp-dependent synthetase and ligase
CJD49_RS05465	COG3328	transposase activity
CJD49_RS05490	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CJD49_RS05500	COG0656	L-ascorbic acid biosynthetic process
CJD49_RS05525	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
CJD49_RS05545	COG2151	metal-sulfur cluster biosynthetic enzyme
CJD49_RS05545	COG0489	protein tyrosine kinase activity
CJD49_RS05550	COG4721	ABC-type cobalt transport system, permease component
CJD49_RS05615	COG4721	ABC-type cobalt transport system, permease component
CJD49_RS05620	COG4172	Belongs to the ABC transporter superfamily
CJD49_RS05625	COG1136	(ABC) transporter
CJD49_RS05630	COG0577	efflux transmembrane transporter activity
CJD49_RS05640	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJD49_RS05730	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJD49_RS05735	COG0569	domain protein
CJD49_RS05750	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJD49_RS05770	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CJD49_RS05790	COG0799	negative regulation of ribosome biogenesis
CJD49_RS05820	COG0406	alpha-ribazole phosphatase activity
CJD49_RS05825	COG0598	Magnesium transport protein CorA
CJD49_RS05855	COG0802	atpase or kinase
CJD49_RS05910	COG0516	GMP reductase activity
CJD49_RS05920	COG1022	Amp-dependent synthetase and ligase
CJD49_RS05950	COG0575	Belongs to the CDS family
CJD49_RS05990	COG1573	uracil-dna glycosylase
CJD49_RS06000	COG0133	tryptophan synthase activity
CJD49_RS06015	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJD49_RS06030	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CJD49_RS06050	COG1716	ATPase activity
CJD49_RS06065	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJD49_RS06070	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
CJD49_RS06125	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJD49_RS06150	COG0045	succinate-CoA ligase (ADP-forming) activity
CJD49_RS06185	COG0438	transferase activity, transferring glycosyl groups
CJD49_RS06190	COG1560	Kdo2-lipid A biosynthetic process
CJD49_RS06205	COG0488	(ABC) transporter
CJD49_RS06215	COG0456	acetyltransferase
CJD49_RS06285	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJD49_RS06295	COG0436	Aminotransferase
CJD49_RS06310	COG0561	phosphatase activity
CJD49_RS06315	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CJD49_RS06340	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJD49_RS06375	COG0488	(ABC) transporter
CJD49_RS06400	COG0450	alkyl hydroperoxide reductase
CJD49_RS06410	COG0583	DNA-binding transcription factor activity
CJD49_RS06450	COG0167	dihydroorotate dehydrogenase activity
CJD49_RS06460	COG0284	orotidine-5'-phosphate decarboxylase activity
CJD49_RS06465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJD49_RS06485	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJD49_RS06505	COG1119	ATPase activity
CJD49_RS06510	COG0297	glycogen (starch) synthase activity
CJD49_RS06530	COG0067	glutamate synthase
CJD49_RS06530	COG0069	glutamate synthase activity
CJD49_RS06530	COG0070	glutamate synthase
CJD49_RS06550	COG2860	membrane
CJD49_RS06555	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJD49_RS06580	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CJD49_RS06605	COG1702	phosphate starvation-inducible protein PhoH
CJD49_RS06610	COG0537	adenosine 5'-monophosphoramidase activity
CJD49_RS06615	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJD49_RS06640	COG2151	metal-sulfur cluster biosynthetic enzyme
CJD49_RS06645	COG0822	iron-sulfur transferase activity
CJD49_RS06655	COG0396	ATPase activity
CJD49_RS06660	COG0719	Fe-S assembly protein
CJD49_RS06670	COG1376	ErfK ybiS ycfS ynhG family protein
CJD49_RS06685	COG1523	belongs to the glycosyl hydrolase 13 family
CJD49_RS06730	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJD49_RS06775	COG0588	phosphoglycerate mutase activity
CJD49_RS06780	COG1950	PFAM Membrane protein of
CJD49_RS06815	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CJD49_RS06830	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CJD49_RS06845	COG1131	(ABC) transporter
CJD49_RS06850	COG1725	Transcriptional regulator
CJD49_RS06860	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
CJD49_RS06885	COG0563	adenylate kinase activity
CJD49_RS06905	COG3039	Transposase
CJD49_RS06925	COG0280	phosphate acetyltransferase
CJD49_RS06925	COG0857	belongs to the CobB CobQ family
CJD49_RS06930	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CJD49_RS06960	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJD49_RS06975	COG0494	nUDIX hydrolase
CJD49_RS06985	COG0469	pyruvate kinase activity
CJD49_RS07000	COG0237	dephospho-CoA kinase activity
CJD49_RS07005	COG0539	negative regulation of cytoplasmic translation
CJD49_RS07020	COG1121	(ABC) transporter
CJD49_RS07035	COG1329	Transcriptional regulator
CJD49_RS07045	COG0745	RESPONSE REGULATOR receiver
CJD49_RS07050	COG2205	protein histidine kinase activity
CJD49_RS07080	COG1316	TRANSCRIPTIONal
CJD49_RS07085	COG1316	TRANSCRIPTIONal
CJD49_RS07110	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJD49_RS07120	COG1760	l-serine dehydratase
CJD49_RS07165	COG1116	anion transmembrane transporter activity
CJD49_RS07190	COG1472	Belongs to the glycosyl hydrolase 3 family
CJD49_RS07200	COG1966	Carbon starvation protein
CJD49_RS07240	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
CJD49_RS07240	COG1918	ferrous iron import across plasma membrane
CJD49_RS07265	COG0363	glucosamine-6-phosphate deaminase activity
CJD49_RS07270	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CJD49_RS07275	COG3340	Belongs to the peptidase S51 family
CJD49_RS07310	COG2233	PERMEase
CJD49_RS07330	COG0012	GTP binding
CJD49_RS07335	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CJD49_RS07345	COG4585	Histidine kinase
CJD49_RS07350	COG2197	response regulator
CJD49_RS07360	COG1136	(ABC) transporter
CJD49_RS07360	COG0577	efflux transmembrane transporter activity
CJD49_RS07370	COG1122	ATPase activity
CJD49_RS07375	COG2873	o-acetylhomoserine
CJD49_RS07405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
CJD49_RS07475	COG1882	Formate acetyltransferase
CJD49_RS07495	COG2011	ABC-type metal ion transport system permease component
CJD49_RS07505	COG1464	Belongs to the NlpA lipoprotein family
CJD49_RS07510	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
CJD49_RS07515	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJD49_RS07540	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJD49_RS07545	COG4975	Glucose uptake
CJD49_RS07550	COG1201	RNA secondary structure unwinding
CJD49_RS07575	COG0187	DNA topoisomerase II activity
CJD49_RS07580	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJD49_RS07590	COG0142	geranyltranstransferase activity
CJD49_RS07610	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJD49_RS07620	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CJD49_RS07645	COG1396	sequence-specific DNA binding
CJD49_RS07655	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CJD49_RS07675	COG2357	RelA SpoT domain protein
CJD49_RS07680	COG0670	Belongs to the BI1 family
CJD49_RS07685	COG3804	dihydrodipicolinate reductase
CJD49_RS07700	COG1131	(ABC) transporter
CJD49_RS07705	COG4585	Histidine kinase
CJD49_RS07710	COG2197	response regulator
CJD49_RS07725	COG0366	Alpha amylase catalytic
CJD49_RS07730	COG2182	Extracellular solute-binding protein
CJD49_RS07745	COG0110	maltose O-acetyltransferase activity
CJD49_RS07755	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
CJD49_RS07785	COG0708	Exodeoxyribonuclease III
CJD49_RS07800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJD49_RS07805	COG0601	transmembrane transport
CJD49_RS07810	COG4166	transmembrane transport
CJD49_RS07820	COG1136	(ABC) transporter
CJD49_RS07825	COG0577	efflux transmembrane transporter activity
CJD49_RS07835	COG0287	Prephenate dehydrogenase
CJD49_RS07850	COG1217	gtp-binding protein TYPA
CJD49_RS07855	COG0477	Major facilitator Superfamily
CJD49_RS07885	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJD49_RS07900	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CJD49_RS07910	COG2017	converts alpha-aldose to the beta-anomer
CJD49_RS07935	COG0285	dihydrofolate synthase activity
CJD49_RS07955	COG0006	proline dipeptidase activity
CJD49_RS07960	COG2816	NAD+ diphosphatase activity
CJD49_RS07980	COG0582	viral genome integration into host DNA
CJD49_RS08065	COG0601	transmembrane transport
CJD49_RS08105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJD49_RS08115	COG0768	penicillin binding
CJD49_RS08140	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJD49_RS08160	COG1230	cation diffusion facilitator family transporter
CJD49_RS08170	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJD49_RS08180	COG1643	Atp-dependent helicase
CJD49_RS08225	COG0587	DNA-directed DNA polymerase activity
CJD49_RS08260	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CJD49_RS08310	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component