locus-tag	class	description
GYM67_RS00010	COG0592	DNA-directed DNA polymerase activity
GYM67_RS00025	COG0187	DNA topoisomerase II activity
GYM67_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GYM67_RS00050	COG2271	Major facilitator Superfamily
GYM67_RS00065	COG1216	Glycosyl transferase, family 2
GYM67_RS00075	COG1472	Belongs to the glycosyl hydrolase 3 family
GYM67_RS00105	COG0583	DNA-binding transcription factor activity
GYM67_RS00110	COG1131	(ABC) transporter
GYM67_RS00115	COG0842	Transport permease protein
GYM67_RS00135	COG1653	transport
GYM67_RS00145	COG0395	ABC-type sugar transport system, permease component
GYM67_RS00150	COG1609	Transcriptional regulator
GYM67_RS00160	COG0577	efflux transmembrane transporter activity
GYM67_RS00160	COG1136	(ABC) transporter
GYM67_RS00170	COG0577	efflux transmembrane transporter activity
GYM67_RS00170	COG1136	(ABC) transporter
GYM67_RS00175	COG1129	ABC transporter
GYM67_RS00190	COG1132	(ABC) transporter
GYM67_RS00195	COG1132	(ABC) transporter
GYM67_RS00200	COG2964	Protein conserved in bacteria
GYM67_RS00205	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GYM67_RS00210	COG1757	Na H antiporter
GYM67_RS00235	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GYM67_RS00240	COG0783	Belongs to the Dps family
GYM67_RS00245	COG1253	flavin adenine dinucleotide binding
GYM67_RS00260	COG1609	Transcriptional regulator
GYM67_RS00265	COG1653	transport
GYM67_RS00270	COG1175	transmembrane transport
GYM67_RS00275	COG0395	ABC-type sugar transport system, permease component
GYM67_RS00290	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GYM67_RS00300	COG0180	Tryptophanyl-tRNA synthetase
GYM67_RS00345	COG0515	serine threonine protein kinase
GYM67_RS00405	COG2217	Heavy metal translocating P-type atpase
GYM67_RS00410	COG1937	Protein conserved in bacteria
GYM67_RS00415	COG1301	dicarboxylic acid transport
GYM67_RS00420	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
GYM67_RS00425	COG1028	Short-chain dehydrogenase reductase Sdr
GYM67_RS00440	COG0343	queuine tRNA-ribosyltransferase activity
GYM67_RS00450	COG2217	Heavy metal translocating P-type atpase
GYM67_RS00455	COG0493	'glutamate synthase
GYM67_RS00475	COG3851	Histidine kinase
GYM67_RS00485	COG1136	(ABC) transporter
GYM67_RS00500	COG1940	carbohydrate kinase activity
GYM67_RS00540	COG0025	NhaP-type Na H and K H
GYM67_RS00545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GYM67_RS00550	COG0590	tRNA wobble adenosine to inosine editing
GYM67_RS00550	COG0037	tRNA processing
GYM67_RS00555	COG0730	response to heat
GYM67_RS00560	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
GYM67_RS00580	COG1175	transmembrane transport
GYM67_RS00585	COG0395	ABC-type sugar transport system, permease component
GYM67_RS00590	COG0366	Alpha amylase catalytic
GYM67_RS00600	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GYM67_RS00605	COG1126	abc transporter atp-binding protein
GYM67_RS00680	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GYM67_RS00700	COG0702	epimerase
GYM67_RS00705	COG2365	Tyrosine phosphatase family
GYM67_RS00710	COG4989	oxidoreductase activity
GYM67_RS00720	COG0778	Nitroreductase
GYM67_RS00730	COG0406	alpha-ribazole phosphatase activity
GYM67_RS00760	COG1609	Transcriptional regulator
GYM67_RS00790	COG0366	Alpha amylase catalytic
GYM67_RS00805	COG0484	heat shock protein binding
GYM67_RS00810	COG0789	Transcriptional regulator
GYM67_RS00825	COG4166	transmembrane transport
GYM67_RS00830	COG0601	transmembrane transport
GYM67_RS00840	COG4172	Belongs to the ABC transporter superfamily
GYM67_RS00845	COG2267	carboxylic ester hydrolase activity
GYM67_RS00850	COG3459	Glycosyltransferase 36 associated
GYM67_RS00855	COG2723	6-phospho-beta-galactosidase activity
GYM67_RS00875	COG2211	Major facilitator Superfamily
GYM67_RS00880	COG3250	beta-galactosidase activity
GYM67_RS00890	COG1501	Belongs to the glycosyl hydrolase 31 family
GYM67_RS00900	COG0586	Pfam SNARE associated Golgi protein
GYM67_RS00905	COG4209	transmembrane transport
GYM67_RS00910	COG0395	ABC-type sugar transport system, permease component
GYM67_RS00930	COG4209	transmembrane transport
GYM67_RS00935	COG0395	ABC-type sugar transport system, permease component
GYM67_RS00960	COG1501	Belongs to the glycosyl hydrolase 31 family
GYM67_RS00965	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
GYM67_RS00970	COG3507	Belongs to the glycosyl hydrolase 43 family
GYM67_RS00985	COG3459	Glycosyltransferase 36 associated
GYM67_RS01030	COG1132	(ABC) transporter
GYM67_RS01035	COG1132	(ABC) transporter
GYM67_RS01050	COG3507	Belongs to the glycosyl hydrolase 43 family
GYM67_RS01060	COG1609	Transcriptional regulator
GYM67_RS01065	COG3507	Belongs to the glycosyl hydrolase 43 family
GYM67_RS01070	COG3940	Belongs to the glycosyl hydrolase 43 family
GYM67_RS01075	COG1653	transport
GYM67_RS01080	COG1175	transmembrane transport
GYM67_RS01085	COG0395	ABC-type sugar transport system, permease component
GYM67_RS01095	COG1609	Transcriptional regulator
GYM67_RS01105	COG4209	transmembrane transport
GYM67_RS01110	COG0395	ABC-type sugar transport system, permease component
GYM67_RS01130	COG0084	hydrolase, TatD family'
GYM67_RS01140	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GYM67_RS01160	COG0395	ABC-type sugar transport system, permease component
GYM67_RS01170	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
GYM67_RS01175	COG3265	gluconokinase activity
GYM67_RS01230	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
GYM67_RS01240	COG0477	Major facilitator Superfamily
GYM67_RS01245	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
GYM67_RS01250	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GYM67_RS01300	COG1175	transmembrane transport
GYM67_RS01310	COG0366	Alpha amylase catalytic
GYM67_RS01335	COG4221	oxidoreductase activity
GYM67_RS01340	COG1335	isochorismatase
GYM67_RS01435	COG2814	Major facilitator Superfamily
GYM67_RS01445	COG1914	H( )-stimulated, divalent metal cation uptake system
GYM67_RS01450	COG1321	iron dependent repressor
GYM67_RS01460	COG1216	Glycosyl transferase, family 2
GYM67_RS01485	COG1088	dTDP-glucose 4,6-dehydratase activity
GYM67_RS01540	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GYM67_RS01550	COG1609	Transcriptional regulator
GYM67_RS01555	COG1328	CTP reductase activity
GYM67_RS01555	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GYM67_RS01560	COG0602	queuosine metabolic process
GYM67_RS01580	COG1252	NADH dehydrogenase
GYM67_RS01585	COG1294	oxidase, subunit
GYM67_RS01590	COG4988	ABC transporter
GYM67_RS01595	COG4987	ABC transporter, CydDC cysteine exporter (CydDC-E) family, permease ATP-binding protein CydC
GYM67_RS01600	COG1271	oxidase subunit
GYM67_RS01615	COG1414	Transcriptional regulator
GYM67_RS01645	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GYM67_RS01665	COG1609	Transcriptional regulator
GYM67_RS01670	COG1129	ABC transporter
GYM67_RS01675	COG1172	Belongs to the binding-protein-dependent transport system permease family
GYM67_RS01685	COG1869	D-ribose catabolic process
GYM67_RS01700	COG0110	maltose O-acetyltransferase activity
GYM67_RS01740	COG2814	Major facilitator Superfamily
GYM67_RS01750	COG0247	lactate metabolic process
GYM67_RS01755	COG1139	Iron-sulfur cluster binding protein
GYM67_RS01760	COG1556	Lactate utilization protein
GYM67_RS01770	COG1837	Belongs to the UPF0109 family
GYM67_RS01795	COG1175	transmembrane transport
GYM67_RS01800	COG0395	ABC-type sugar transport system, permease component
GYM67_RS01815	COG1175	transmembrane transport
GYM67_RS01820	COG0395	ABC-type sugar transport system, permease component
GYM67_RS01840	COG0505	Belongs to the CarA family
GYM67_RS01845	COG0488	(ABC) transporter
GYM67_RS01850	COG0440	acetolactate synthase activity
GYM67_RS01890	COG0667	Aldo Keto reductase
GYM67_RS01970	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GYM67_RS01975	COG1609	Transcriptional regulator
GYM67_RS02010	COG0656	L-ascorbic acid biosynthetic process
GYM67_RS02035	COG0395	ABC-type sugar transport system, permease component
GYM67_RS02045	COG1609	Transcriptional regulator
GYM67_RS02050	COG2814	Major facilitator Superfamily
GYM67_RS02065	COG0581	inorganic phosphate transmembrane transporter activity
GYM67_RS02085	COG2252	PERMEase
GYM67_RS02095	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GYM67_RS02145	COG0095	Lipoate-protein ligase
GYM67_RS02150	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GYM67_RS02155	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GYM67_RS02160	COG1902	pentaerythritol trinitrate reductase activity
GYM67_RS02165	COG1216	Glycosyl transferase, family 2
GYM67_RS02170	COG1349	DNA-binding transcription factor activity
GYM67_RS02180	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GYM67_RS02195	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GYM67_RS02200	COG1194	a g-specific adenine glycosylase
GYM67_RS02230	COG0714	Associated with various cellular activities
GYM67_RS02295	COG3152	Membrane
GYM67_RS02320	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
GYM67_RS02355	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GYM67_RS02360	COG1063	alcohol dehydrogenase
GYM67_RS02395	COG1929	Belongs to the glycerate kinase type-1 family
GYM67_RS02400	COG2610	gluconate transmembrane transporter activity
GYM67_RS02405	COG3835	regulator
GYM67_RS02420	COG2814	Major facilitator Superfamily
GYM67_RS02460	COG0477	Major facilitator Superfamily
GYM67_RS02500	COG3863	Permuted papain-like amidase enzyme, YaeF/YiiX, C92 family
GYM67_RS02530	COG0535	radical SAM domain protein
GYM67_RS02535	COG1994	Peptidase M50
GYM67_RS02545	COG1136	(ABC) transporter
GYM67_RS02545	COG0577	efflux transmembrane transporter activity
GYM67_RS02640	COG1570	exodeoxyribonuclease VII activity
GYM67_RS02645	COG1924	4 iron, 4 sulfur cluster binding
GYM67_RS02650	COG0110	maltose O-acetyltransferase activity
GYM67_RS02660	COG2211	Major facilitator Superfamily
GYM67_RS02670	COG1874	Beta-galactosidase
GYM67_RS02690	COG0667	Aldo Keto reductase
GYM67_RS02710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GYM67_RS02720	COG0613	PHP domain protein
GYM67_RS02755	COG0477	Major facilitator Superfamily
GYM67_RS02795	COG1473	amidohydrolase
GYM67_RS02835	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GYM67_RS02865	COG0587	DNA-directed DNA polymerase activity
GYM67_RS02910	COG1643	Atp-dependent helicase
GYM67_RS02915	COG2813	Specifically methylates the guanine in position
GYM67_RS02920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GYM67_RS02970	COG0768	penicillin binding
GYM67_RS02980	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GYM67_RS02995	COG0772	Belongs to the SEDS family
GYM67_RS03020	COG2207	Transcriptional regulator
GYM67_RS03020	COG0614	abc-type fe3 -hydroxamate transport system, periplasmic component
GYM67_RS03065	COG0281	malic enzyme
GYM67_RS03070	COG0471	metal ion transport
GYM67_RS03075	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYM67_RS03100	COG1653	transport
GYM67_RS03105	COG1175	transmembrane transport
GYM67_RS03110	COG3833	ABC-type maltose transport systems, permease component
GYM67_RS03130	COG1175	transmembrane transport
GYM67_RS03135	COG0395	ABC-type sugar transport system, permease component
GYM67_RS03145	COG1609	Transcriptional regulator
GYM67_RS03155	COG1070	Carbohydrate kinase
GYM67_RS03160	COG4213	ABC transporter substrate-binding protein
GYM67_RS03170	COG4214	carbohydrate transport
GYM67_RS03185	COG0006	proline dipeptidase activity
GYM67_RS03190	COG0285	dihydrofolate synthase activity
GYM67_RS03195	COG1196	nuclear chromosome segregation
GYM67_RS03200	COG1794	racemase activity, acting on amino acids and derivatives
GYM67_RS03220	COG1595	DNA-templated transcription, initiation
GYM67_RS03230	COG2017	converts alpha-aldose to the beta-anomer
GYM67_RS03240	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GYM67_RS03255	COG1393	Belongs to the ArsC family
GYM67_RS03265	COG1687	branched-chain amino acid
GYM67_RS03270	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GYM67_RS03280	COG0367	asparagine synthase
GYM67_RS03290	COG2376	Dihydroxyacetone kinase
GYM67_RS03310	COG0698	ribose 5-phosphate isomerase
GYM67_RS03315	COG0149	triose-phosphate isomerase activity
GYM67_RS03320	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GYM67_RS03350	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GYM67_RS03355	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GYM67_RS03360	COG1217	gtp-binding protein TYPA
GYM67_RS03375	COG0287	Prephenate dehydrogenase
GYM67_RS03390	COG4166	transmembrane transport
GYM67_RS03400	COG0601	transmembrane transport
GYM67_RS03405	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GYM67_RS03435	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GYM67_RS03440	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
GYM67_RS03445	COG0670	Belongs to the BI1 family
GYM67_RS03450	COG0656	L-ascorbic acid biosynthetic process
GYM67_RS03455	COG2357	RelA SpoT domain protein
GYM67_RS03470	COG0789	Transcriptional regulator
GYM67_RS03490	COG1546	Belongs to the CinA family
GYM67_RS03490	COG1058	Belongs to the CinA family
GYM67_RS03495	COG1396	sequence-specific DNA binding
GYM67_RS03510	COG2137	regulation of response to DNA damage stimulus
GYM67_RS03520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GYM67_RS03530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GYM67_RS03550	COG0142	geranyltranstransferase activity
GYM67_RS03560	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GYM67_RS03565	COG0187	DNA topoisomerase II activity
GYM67_RS03570	COG1201	RNA secondary structure unwinding
GYM67_RS03575	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GYM67_RS03580	COG1015	Phosphotransfer between the C1 and C5 carbon atoms of pentose
GYM67_RS03600	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GYM67_RS03605	COG1196	nuclear chromosome segregation
GYM67_RS03620	COG1126	abc transporter atp-binding protein
GYM67_RS03625	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GYM67_RS03630	COG0765	amino acid transport
GYM67_RS03635	COG0765	amino acid transport
GYM67_RS03645	COG1126	abc transporter atp-binding protein
GYM67_RS03650	COG0765	amino acid transport
GYM67_RS03660	COG2814	Major facilitator Superfamily
GYM67_RS03685	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GYM67_RS03715	COG1882	Formate acetyltransferase
GYM67_RS03720	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GYM67_RS03755	COG0497	DNA recombination
GYM67_RS03765	COG1131	(ABC) transporter
GYM67_RS03795	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GYM67_RS03820	COG0799	negative regulation of ribosome biogenesis
GYM67_RS03825	COG0406	alpha-ribazole phosphatase activity
GYM67_RS03835	COG0371	Dehydrogenase
GYM67_RS04030	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
GYM67_RS04135	COG4974	Belongs to the 'phage' integrase family
GYM67_RS04170	COG0598	Magnesium transport protein CorA
GYM67_RS04200	COG0802	atpase or kinase
GYM67_RS04205	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GYM67_RS04225	COG3534	alpha-L-arabinofuranosidase
GYM67_RS04240	COG0395	ABC-type sugar transport system, permease component
GYM67_RS04255	COG1022	Amp-dependent synthetase and ligase
GYM67_RS04270	COG0516	GMP reductase activity
GYM67_RS04330	COG0133	tryptophan synthase activity
GYM67_RS04345	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GYM67_RS04360	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GYM67_RS04400	COG4581	dead DEAH box helicase
GYM67_RS04415	COG4284	Utp--glucose-1-phosphate uridylyltransferase
GYM67_RS04430	COG2814	Major facilitator Superfamily
GYM67_RS04440	COG2197	response regulator
GYM67_RS04445	COG4585	Histidine kinase
GYM67_RS04490	COG1063	alcohol dehydrogenase
GYM67_RS04545	COG1012	belongs to the aldehyde dehydrogenase family
GYM67_RS04565	COG0045	succinate-CoA ligase (ADP-forming) activity
GYM67_RS04600	COG0438	transferase activity, transferring glycosyl groups
GYM67_RS04610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GYM67_RS04645	COG2964	Protein conserved in bacteria
GYM67_RS04655	COG3001	Fructosamine kinase
GYM67_RS04675	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GYM67_RS04685	COG0477	Major facilitator Superfamily
GYM67_RS04695	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GYM67_RS04720	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GYM67_RS04745	COG0488	(ABC) transporter
GYM67_RS04750	COG1285	pathogenesis
GYM67_RS04755	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
GYM67_RS04760	COG0588	phosphoglycerate mutase activity
GYM67_RS04765	COG0583	DNA-binding transcription factor activity
GYM67_RS04780	COG0167	dihydroorotate dehydrogenase activity
GYM67_RS04785	COG0543	2 iron, 2 sulfur cluster binding
GYM67_RS04790	COG0284	orotidine-5'-phosphate decarboxylase activity
GYM67_RS04795	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GYM67_RS04830	COG4214	carbohydrate transport
GYM67_RS04850	COG1129	ABC transporter
GYM67_RS04870	COG2062	phosphohistidine phosphatase, SixA
GYM67_RS04890	COG1119	ATPase activity
GYM67_RS04905	COG0067	glutamate synthase
GYM67_RS04905	COG0070	glutamate synthase
GYM67_RS04905	COG0069	glutamate synthase activity
GYM67_RS04925	COG2860	membrane
GYM67_RS04930	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GYM67_RS04965	COG0537	adenosine 5'-monophosphoramidase activity
GYM67_RS04980	COG0789	Transcriptional regulator
GYM67_RS04980	COG4978	Transcriptional regulator
GYM67_RS04985	COG2272	Belongs to the type-B carboxylesterase lipase family
GYM67_RS04990	COG2223	nitrite transmembrane transporter activity
GYM67_RS05000	COG2233	PERMEase
GYM67_RS05020	COG0396	ATPase activity
GYM67_RS05025	COG0719	Fe-S assembly protein
GYM67_RS05045	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GYM67_RS05090	COG0588	phosphoglycerate mutase activity
GYM67_RS05105	COG2211	Major facilitator Superfamily
GYM67_RS05110	COG2249	NAD(P)H dehydrogenase (quinone) activity
GYM67_RS05125	COG1131	(ABC) transporter
GYM67_RS05130	COG4585	Histidine kinase
GYM67_RS05135	COG2197	response regulator
GYM67_RS05160	COG0436	Aminotransferase
GYM67_RS05165	COG2390	Transcriptional regulator
GYM67_RS05170	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GYM67_RS05175	COG0738	Major facilitator superfamily
GYM67_RS05185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYM67_RS05190	COG0300	oxidoreductase activity
GYM67_RS05200	COG2814	Major facilitator Superfamily
GYM67_RS05205	COG1446	asparaginase
GYM67_RS05210	COG1309	transcriptional regulator
GYM67_RS05235	COG2211	Major facilitator Superfamily
GYM67_RS05240	COG1609	Transcriptional regulator
GYM67_RS05250	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GYM67_RS05255	COG0483	inositol monophosphate 1-phosphatase activity
GYM67_RS05270	COG1131	(ABC) transporter
GYM67_RS05300	COG0494	nUDIX hydrolase
GYM67_RS05305	COG0469	pyruvate kinase activity
GYM67_RS05320	COG0237	dephospho-CoA kinase activity
GYM67_RS05325	COG0539	negative regulation of cytoplasmic translation
GYM67_RS05335	COG1121	(ABC) transporter
GYM67_RS05355	COG0745	RESPONSE REGULATOR receiver
GYM67_RS05360	COG2205	protein histidine kinase activity
GYM67_RS05365	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GYM67_RS05370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GYM67_RS05405	COG1316	TRANSCRIPTIONal
GYM67_RS05410	COG1316	TRANSCRIPTIONal
GYM67_RS05415	COG1674	ftsk spoiiie
GYM67_RS05435	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GYM67_RS05495	COG2249	NAD(P)H dehydrogenase (quinone) activity
GYM67_RS05520	COG0385	Bile acid
GYM67_RS05525	COG1376	ErfK ybiS ycfS ynhG family protein
GYM67_RS05535	COG1376	ErfK ybiS ycfS ynhG family protein
GYM67_RS05550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GYM67_RS05560	COG1609	Transcriptional regulator
GYM67_RS05565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYM67_RS05570	COG3851	Histidine kinase
GYM67_RS05575	COG2197	response regulator
GYM67_RS05585	COG0577	efflux transmembrane transporter activity
GYM67_RS05585	COG1136	(ABC) transporter
GYM67_RS05595	COG0577	efflux transmembrane transporter activity
GYM67_RS05595	COG1136	(ABC) transporter
GYM67_RS05600	COG2873	o-acetylhomoserine
GYM67_RS05645	COG1611	Belongs to the LOG family
GYM67_RS05660	COG1131	(ABC) transporter
GYM67_RS05745	COG0647	UMP catabolic process
GYM67_RS05825	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYM67_RS05835	COG4172	Belongs to the ABC transporter superfamily
GYM67_RS05840	COG4721	ABC-type cobalt transport system, permease component
GYM67_RS05875	COG2151	metal-sulfur cluster biosynthetic enzyme
GYM67_RS05875	COG0489	protein tyrosine kinase activity
GYM67_RS05910	COG1940	carbohydrate kinase activity
GYM67_RS05925	COG3601	Mediates riboflavin uptake, may also transport FMN and roseoflavin. Probably a riboflavin-binding protein that interacts with the energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates. The substrates themselves are bound by transmembrane, not extracytoplasmic soluble proteins
GYM67_RS05945	COG1278	Cold shock
GYM67_RS05955	COG0745	RESPONSE REGULATOR receiver
GYM67_RS05975	COG1278	Cold shock
GYM67_RS05990	COG0714	Associated with various cellular activities
GYM67_RS06030	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GYM67_RS06105	COG1940	carbohydrate kinase activity
GYM67_RS06115	COG1882	Formate acetyltransferase
GYM67_RS06125	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GYM67_RS06245	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GYM67_RS06265	COG1063	alcohol dehydrogenase
GYM67_RS06270	COG2205	protein histidine kinase activity
GYM67_RS06275	COG0745	RESPONSE REGULATOR receiver
GYM67_RS06300	COG1464	Belongs to the NlpA lipoprotein family
GYM67_RS06305	COG1464	Belongs to the NlpA lipoprotein family
GYM67_RS06310	COG2011	ABC-type metal ion transport system permease component
GYM67_RS06345	COG0151	Belongs to the GarS family
GYM67_RS06350	COG1368	sulfuric ester hydrolase activity
GYM67_RS06365	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GYM67_RS06370	COG0735	belongs to the Fur family
GYM67_RS06375	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GYM67_RS06380	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GYM67_RS06385	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GYM67_RS06425	COG2094	Belongs to the DNA glycosylase MPG family
GYM67_RS06435	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GYM67_RS06440	COG0477	Major facilitator Superfamily
GYM67_RS06460	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GYM67_RS06475	COG0358	DNA primase activity
GYM67_RS06485	COG1764	response to oxidative stress
GYM67_RS06490	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GYM67_RS06500	COG1609	Transcriptional regulator
GYM67_RS06505	COG4948	Mandelate Racemase Muconate Lactonizing
GYM67_RS06525	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GYM67_RS06540	COG0395	ABC-type sugar transport system, permease component
GYM67_RS06545	COG1175	transmembrane transport
GYM67_RS06550	COG1653	transport
GYM67_RS06555	COG1609	Transcriptional regulator
GYM67_RS06565	COG0514	ATP-dependent DNA helicase (RecQ)
GYM67_RS06570	COG4608	Belongs to the ABC transporter superfamily
GYM67_RS06580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GYM67_RS06590	COG0747	negative chemotaxis
GYM67_RS06605	COG0564	pseudouridine synthase activity
GYM67_RS06610	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GYM67_RS06620	COG0765	amino acid transport
GYM67_RS06635	COG3942	CHAP domain
GYM67_RS06635	COG1388	LysM domain
GYM67_RS06640	COG2177	Part of the ABC transporter FtsEX involved in
GYM67_RS06650	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GYM67_RS06655	COG2171	N-acyltransferase activity
GYM67_RS06665	COG0024	Methionine aminopeptidase
GYM67_RS06675	COG3590	peptidase
GYM67_RS06685	COG0708	Exodeoxyribonuclease III
GYM67_RS06695	COG1131	(ABC) transporter
GYM67_RS06715	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GYM67_RS06730	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GYM67_RS06735	COG0009	L-threonylcarbamoyladenylate synthase
GYM67_RS06760	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GYM67_RS06765	COG2964	Protein conserved in bacteria
GYM67_RS06785	COG1946	Acyl-CoA thioesterase
GYM67_RS06800	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GYM67_RS06805	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GYM67_RS06815	COG2027	D-alanyl-D-alanine carboxypeptidase
GYM67_RS06830	COG1215	transferase activity, transferring glycosyl groups
GYM67_RS06840	COG1216	Glycosyl transferase, family 2
GYM67_RS06850	COG1070	Carbohydrate kinase
GYM67_RS06870	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GYM67_RS06905	COG0589	response to stress
GYM67_RS06910	COG0791	NLP P60 protein
GYM67_RS06915	COG1388	LysM domain
GYM67_RS06915	COG3942	CHAP domain
GYM67_RS06930	COG5002	protein histidine kinase activity
GYM67_RS06945	COG1575	Belongs to the MenA family. Type 1 subfamily
GYM67_RS06950	COG1575	Belongs to the MenA family. Type 1 subfamily
GYM67_RS06955	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GYM67_RS07000	COG4585	Histidine kinase
GYM67_RS07005	COG2197	response regulator
GYM67_RS07015	COG3340	Belongs to the peptidase S51 family
GYM67_RS07045	COG0814	amino acid
GYM67_RS07050	COG1760	l-serine dehydratase
GYM67_RS07055	COG1760	l-serine dehydratase
GYM67_RS07060	COG1597	lipid kinase activity
GYM67_RS07060	COG1803	Methylglyoxal synthase
GYM67_RS07070	COG0328	RNA-DNA hybrid ribonuclease activity
GYM67_RS07110	COG0196	riboflavin kinase activity
GYM67_RS07140	COG1501	Belongs to the glycosyl hydrolase 31 family
GYM67_RS07145	COG0395	ABC-type sugar transport system, permease component
GYM67_RS07160	COG1609	Transcriptional regulator
GYM67_RS07205	COG0071	Belongs to the small heat shock protein (HSP20) family
GYM67_RS07210	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GYM67_RS07225	COG1132	(ABC) transporter
GYM67_RS07230	COG1132	(ABC) transporter
GYM67_RS07300	COG0255	Belongs to the universal ribosomal protein uL29 family
GYM67_RS07350	COG1454	alcohol dehydrogenase
GYM67_RS07350	COG1012	belongs to the aldehyde dehydrogenase family
GYM67_RS07370	COG1739	Uncharacterized protein family UPF0029
GYM67_RS07380	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GYM67_RS07390	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
GYM67_RS07395	COG0531	amino acid
GYM67_RS07400	COG2721	sulfolactate sulfo-lyase activity
GYM67_RS07415	COG0395	ABC-type sugar transport system, permease component
GYM67_RS07420	COG1175	transmembrane transport
GYM67_RS07430	COG1609	Transcriptional regulator
GYM67_RS07435	COG1904	glucuronate isomerase
GYM67_RS07440	COG1609	Transcriptional regulator
GYM67_RS07445	COG1609	Transcriptional regulator
GYM67_RS07450	COG0246	Mannitol dehydrogenase
GYM67_RS07455	COG1312	Catalyzes the dehydration of D-mannonate
GYM67_RS07460	COG0246	Mannitol dehydrogenase
GYM67_RS07465	COG0800	Aldolase
GYM67_RS07470	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GYM67_RS07475	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GYM67_RS07480	COG2873	o-acetylhomoserine
GYM67_RS07505	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYM67_RS07510	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYM67_RS07520	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GYM67_RS07525	COG1780	Probably involved in ribonucleotide reductase function
GYM67_RS07530	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GYM67_RS07560	COG1970	mechanosensitive ion channel activity
GYM67_RS07610	COG0395	ABC-type sugar transport system, permease component
GYM67_RS07630	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
GYM67_RS07635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GYM67_RS07640	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GYM67_RS07645	COG3579	cysteine-type endopeptidase activity
GYM67_RS07685	COG1704	LemA family
GYM67_RS07730	COG1518	maintenance of DNA repeat elements
GYM67_RS07790	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GYM67_RS07795	COG4770	biotin carboxylase activity
GYM67_RS07840	COG0436	Aminotransferase
GYM67_RS07865	COG1530	ribonuclease E activity
GYM67_RS07885	COG0083	homoserine kinase activity
GYM67_RS07890	COG0460	homoserine dehydrogenase
GYM67_RS07905	COG0251	oxidation-reduction process
GYM67_RS07910	COG0028	Belongs to the TPP enzyme family
GYM67_RS07940	COG0545	Peptidyl-prolyl cis-trans isomerase
GYM67_RS07950	COG1126	abc transporter atp-binding protein
GYM67_RS07955	COG0765	amino acid transport
GYM67_RS07960	COG0765	amino acid transport
GYM67_RS07975	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GYM67_RS08010	COG0356	it plays a direct role in the translocation of protons across the membrane
GYM67_RS08120	COG4974	Belongs to the 'phage' integrase family
GYM67_RS08145	COG1333	cytochrome c biogenesis protein
GYM67_RS08160	COG2271	Major facilitator Superfamily
GYM67_RS08170	COG0395	ABC-type sugar transport system, permease component
GYM67_RS08175	COG4209	transmembrane transport
GYM67_RS08180	COG1609	Transcriptional regulator
GYM67_RS08195	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GYM67_RS08220	COG0745	RESPONSE REGULATOR receiver
GYM67_RS08230	COG0747	negative chemotaxis
GYM67_RS08245	COG1605	Chorismate mutase
GYM67_RS08245	COG0287	Prephenate dehydrogenase
GYM67_RS08310	COG1322	Protein conserved in bacteria
GYM67_RS08315	COG2217	Heavy metal translocating P-type atpase
GYM67_RS08325	COG0179	Fumarylacetoacetate (FAA) hydrolase
GYM67_RS08345	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GYM67_RS08370	COG3037	sugar-specific permease SgaT UlaA
GYM67_RS08385	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GYM67_RS08390	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GYM67_RS08395	COG1609	Transcriptional regulator
GYM67_RS08400	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GYM67_RS08410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GYM67_RS08410	COG1754	DNA topoisomerase type I activity
GYM67_RS08445	COG1260	myo-inositol-1-phosphate synthase
GYM67_RS08450	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GYM67_RS08470	COG0527	aspartate kinase activity
GYM67_RS08525	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GYM67_RS08530	COG0494	nUDIX hydrolase
GYM67_RS08530	COG0406	alpha-ribazole phosphatase activity
GYM67_RS08555	COG0584	glycerophosphoryl diester phosphodiesterase
GYM67_RS08580	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GYM67_RS08585	COG0305	Participates in initiation and elongation during chromosome replication
GYM67_RS08590	COG0534	Mate efflux family protein
GYM67_RS08620	COG1940	carbohydrate kinase activity
GYM67_RS08630	COG0395	ABC-type sugar transport system, permease component
GYM67_RS08690	COG3152	Membrane
GYM67_RS08750	COG1653	transport
GYM67_RS08760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GYM67_RS08795	COG1131	(ABC) transporter
GYM67_RS08810	COG1122	ATPase activity
GYM67_RS08815	COG1122	ATPase activity
GYM67_RS08850	COG2514	catechol 2,3-dioxygenase activity
GYM67_RS08855	COG1024	Enoyl-CoA hydratase
GYM67_RS08855	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYM67_RS08885	COG0477	Major facilitator Superfamily
GYM67_RS08895	COG0395	ABC-type sugar transport system, permease component
GYM67_RS08900	COG1175	transmembrane transport
GYM67_RS08910	COG1609	Transcriptional regulator
GYM67_RS08920	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GYM67_RS08950	COG3470	protein probably involved in high-affinity Fe2 transport
GYM67_RS08955	COG0672	)-iron permease
GYM67_RS08960	COG1113	amino acid transport
GYM67_RS08965	COG1113	amino acid transport
GYM67_RS08970	COG1250	3-hydroxyacyl-CoA dehydrogenase
GYM67_RS08975	COG0833	amino acid
GYM67_RS08980	COG0833	amino acid
GYM67_RS08995	COG3048	D-serine ammonia-lyase activity
GYM67_RS09000	COG2610	gluconate transmembrane transporter activity
GYM67_RS09010	COG0477	Major facilitator Superfamily
GYM67_RS09025	COG0191	fructose-bisphosphate aldolase activity
GYM67_RS09060	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GYM67_RS09070	COG3842	ATPase activity
GYM67_RS09095	COG3583	domain protein
GYM67_RS09125	COG0617	tRNA 3'-terminal CCA addition
GYM67_RS09145	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GYM67_RS09150	COG1181	Belongs to the D-alanine--D-alanine ligase family
GYM67_RS09160	COG0492	ferredoxin-NADP+ reductase activity
GYM67_RS09170	COG1192	Involved in chromosome partitioning
GYM67_RS09180	COG1847	R3H domain protein
GYM67_RS09270	COG2205	protein histidine kinase activity