locus-tag	class	description
BBPR_0002	COG0592	DNA-directed DNA polymerase activity
BBPR_0005	COG0187	DNA topoisomerase II activity
BBPR_0006	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBPR_0019	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BBPR_0021	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBPR_0024	COG1970	mechanosensitive ion channel activity
BBPR_0025	COG3534	alpha-L-arabinofuranosidase
BBPR_0029	COG1609	Transcriptional regulator
BBPR_0030	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBPR_0034	COG0783	Belongs to the Dps family
BBPR_0036	COG1253	flavin adenine dinucleotide binding
BBPR_0038	COG0288	reversible hydration of carbon dioxide
BBPR_0042	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BBPR_0046	COG0180	Tryptophanyl-tRNA synthetase
BBPR_0050	COG1088	dTDP-glucose 4,6-dehydratase activity
BBPR_0053	COG0463	Glycosyl transferase, family 2
BBPR_0054	COG2801	Transposase and inactivated derivatives
BBPR_0072	COG1216	Glycosyl transferase, family 2
BBPR_0072	COG1442	glycosyl transferase family 8
BBPR_0080	COG1088	dTDP-glucose 4,6-dehydratase activity
BBPR_0083	COG2826	transposase and inactivated derivatives, IS30 family
BBPR_0087	COG2814	Major facilitator Superfamily
BBPR_0088	COG2801	Transposase and inactivated derivatives
BBPR_0092	COG0058	SHG alpha-glucan phosphorylase activity
BBPR_0103	COG0515	serine threonine protein kinase
BBPR_0104	COG0768	penicillin binding
BBPR_0117	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBPR_0117	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BBPR_0120	COG0494	nUDIX hydrolase
BBPR_0125	COG0343	queuine tRNA-ribosyltransferase activity
BBPR_0127	COG2217	Heavy metal translocating P-type atpase
BBPR_0139	COG0191	fructose-bisphosphate aldolase activity
BBPR_0146	COG0477	Major facilitator Superfamily
BBPR_0150	COG3250	beta-galactosidase activity
BBPR_0151	COG1113	amino acid transport
BBPR_0153	COG1136	(ABC) transporter
BBPR_0153	COG0577	efflux transmembrane transporter activity
BBPR_0168	COG0477	Major facilitator Superfamily
BBPR_0170	COG2801	Transposase and inactivated derivatives
BBPR_0173	COG2977	Belongs to the P-Pant transferase superfamily
BBPR_0181	COG3843	relaxase mobilization nuclease domain protein
BBPR_0188	COG0667	Aldo Keto reductase
BBPR_0190	COG1846	Transcriptional regulator
BBPR_0192	COG1132	(ABC) transporter
BBPR_0202	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBPR_0204	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBPR_0212	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBPR_0215	COG0167	dihydroorotate dehydrogenase activity
BBPR_0217	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBPR_0219	COG1309	transcriptional regulator
BBPR_0230	COG4948	Mandelate Racemase Muconate Lactonizing
BBPR_0231	COG1028	Short-chain dehydrogenase reductase Sdr
BBPR_0234	COG0251	oxidation-reduction process
BBPR_0235	COG0584	glycerophosphoryl diester phosphodiesterase
BBPR_0239	COG1263	PTS System
BBPR_0239	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBPR_0239	COG2190	(PTS) system
BBPR_0240	COG1263	PTS System
BBPR_0240	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBPR_0240	COG2190	(PTS) system
BBPR_0241	COG0460	homoserine dehydrogenase
BBPR_0242	COG0083	homoserine kinase activity
BBPR_0246	COG1136	(ABC) transporter
BBPR_0249	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBPR_0251	COG1530	ribonuclease E activity
BBPR_0257	COG0436	Aminotransferase
BBPR_0258	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBPR_0259	COG0250	Participates in transcription elongation, termination and antitermination
BBPR_0263	COG0584	glycerophosphoryl diester phosphodiesterase
BBPR_0264	COG0366	Alpha amylase catalytic
BBPR_0277	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBPR_0286	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBPR_0291	COG0436	Aminotransferase
BBPR_0297	COG1022	Amp-dependent synthetase and ligase
BBPR_0310	COG4106	trans-aconitate 2-methyltransferase activity
BBPR_0316	COG0789	Transcriptional regulator
BBPR_0317	COG2270	Major facilitator Superfamily
BBPR_0324	COG1301	dicarboxylic acid transport
BBPR_0325	COG0742	ribosomal rna small subunit methyltransferase
BBPR_0327	COG0071	Belongs to the small heat shock protein (HSP20) family
BBPR_0330	COG1837	Belongs to the UPF0109 family
BBPR_0332	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBPR_0339	COG0519	Catalyzes the synthesis of GMP from XMP
BBPR_0340	COG0488	(ABC) transporter
BBPR_0348	COG0440	acetolactate synthase activity
BBPR_0359	COG1285	pathogenesis
BBPR_0360	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBPR_0362	COG1116	anion transmembrane transporter activity
BBPR_0366	COG3775	system Galactitol-specific IIC component
BBPR_0372	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBPR_0373	COG1609	Transcriptional regulator
BBPR_0381	COG1609	Transcriptional regulator
BBPR_0382	COG0656	L-ascorbic acid biosynthetic process
BBPR_0385	COG2814	Major facilitator Superfamily
BBPR_0388	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BBPR_0399	COG0095	Lipoate-protein ligase
BBPR_0400	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBPR_0401	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBPR_0404	COG0167	dihydroorotate dehydrogenase activity
BBPR_0405	COG1349	DNA-binding transcription factor activity
BBPR_0407	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BBPR_0408	COG0477	Major facilitator Superfamily
BBPR_0413	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BBPR_0425	COG0714	Associated with various cellular activities
BBPR_0437	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBPR_0445	COG0436	Aminotransferase
BBPR_0446	COG0248	Ppx GppA phosphatase
BBPR_0449	COG2210	Belongs to the sulfur carrier protein TusA family
BBPR_0453	COG1722	exodeoxyribonuclease VII activity
BBPR_0454	COG1570	exodeoxyribonuclease VII activity
BBPR_0455	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBPR_0455	COG1328	CTP reductase activity
BBPR_0456	COG0602	queuosine metabolic process
BBPR_0462	COG1132	(ABC) transporter
BBPR_0463	COG1132	(ABC) transporter
BBPR_0466	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBPR_0468	COG0613	PHP domain protein
BBPR_0473	COG3480	Lon protease (S16) C-terminal proteolytic domain
BBPR_0477	COG0351	phosphomethylpyrimidine kinase
BBPR_0478	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBPR_0482	COG3250	beta-galactosidase activity
BBPR_0485	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBPR_0495	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBPR_0496	COG2884	Cell division ATP-binding protein ftsE
BBPR_0497	COG2177	Part of the ABC transporter FtsEX involved in
BBPR_0498	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBPR_0498	COG3942	CHAP domain
BBPR_0500	COG0564	pseudouridine synthase activity
BBPR_0511	COG3878	Protein conserved in bacteria
BBPR_0513	COG1621	beta-fructofuranosidase activity
BBPR_0514	COG0587	DNA-directed DNA polymerase activity
BBPR_0517	COG4716	Myosin-crossreactive antigen
BBPR_0519	COG0656	L-ascorbic acid biosynthetic process
BBPR_0535	COG1643	Atp-dependent helicase
BBPR_0536	COG2813	Specifically methylates the guanine in position
BBPR_0538	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBPR_0545	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBPR_0550	COG0768	penicillin binding
BBPR_0552	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBPR_0569	COG0601	transmembrane transport
BBPR_0570	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBPR_0572	COG0006	proline dipeptidase activity
BBPR_0575	COG0285	dihydrofolate synthase activity
BBPR_0576	COG1196	nuclear chromosome segregation
BBPR_0577	COG1794	racemase activity, acting on amino acids and derivatives
BBPR_0582	COG1595	DNA-templated transcription, initiation
BBPR_0584	COG2017	converts alpha-aldose to the beta-anomer
BBPR_0586	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBPR_0591	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBPR_0597	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBPR_0599	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BBPR_0600	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BBPR_0602	COG1104	cysteine desulfurase activity
BBPR_0603	COG1217	gtp-binding protein TYPA
BBPR_0606	COG0287	Prephenate dehydrogenase
BBPR_0614	COG0708	Exodeoxyribonuclease III
BBPR_0627	COG1011	Hydrolase
BBPR_0629	COG0560	Phosphoserine phosphatase
BBPR_0630	COG1222	aaa ATPase
BBPR_0631	COG4122	O-methyltransferase activity
BBPR_0637	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBPR_0646	COG0714	Associated with various cellular activities
BBPR_0649	COG1278	Cold shock
BBPR_0653	COG0745	RESPONSE REGULATOR receiver
BBPR_0654	COG2205	protein histidine kinase activity
BBPR_0655	COG1278	Cold shock
BBPR_0663	COG1196	nuclear chromosome segregation
BBPR_0668	COG1126	abc transporter atp-binding protein
BBPR_0669	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBPR_0670	COG0765	amino acid transport
BBPR_0671	COG0765	amino acid transport
BBPR_0672	COG2326	polyphosphate kinase activity
BBPR_0675	COG2814	Major facilitator Superfamily
BBPR_0681	COG1122	ATPase activity
BBPR_0694	COG1136	(ABC) transporter
BBPR_0699	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
BBPR_0704	COG1682	transport, permease protein
BBPR_0705	COG1134	teichoic acid transport
BBPR_0709	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BBPR_0710	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBPR_0716	COG1760	l-serine dehydratase
BBPR_0718	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBPR_0724	COG1674	ftsk spoiiie
BBPR_0725	COG1316	TRANSCRIPTIONal
BBPR_0731	COG1040	competence protein
BBPR_0733	COG2205	protein histidine kinase activity
BBPR_0734	COG0745	RESPONSE REGULATOR receiver
BBPR_0739	COG1121	(ABC) transporter
BBPR_0742	COG0539	negative regulation of cytoplasmic translation
BBPR_0747	COG0469	pyruvate kinase activity
BBPR_0748	COG0494	nUDIX hydrolase
BBPR_0751	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBPR_0752	COG0494	nUDIX hydrolase
BBPR_0755	COG4974	Belongs to the 'phage' integrase family
BBPR_0756	COG3340	Belongs to the peptidase S51 family
BBPR_0758	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBPR_0759	COG0857	belongs to the CobB CobQ family
BBPR_0759	COG0280	phosphate acetyltransferase
BBPR_0760	COG4868	Belongs to the UPF0371 family
BBPR_0769	COG0306	phosphate transporter
BBPR_0771	COG2197	response regulator
BBPR_0772	COG4585	Histidine kinase
BBPR_0774	COG1131	(ABC) transporter
BBPR_0778	COG2826	transposase and inactivated derivatives, IS30 family
BBPR_0782	COG2801	Transposase and inactivated derivatives
BBPR_0785	COG1335	isochorismatase
BBPR_0787	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBPR_0791	COG2755	lipolytic protein G-D-S-L family
BBPR_0791	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BBPR_0797	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BBPR_0797	COG2755	lipolytic protein G-D-S-L family
BBPR_0807	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBPR_0813	COG0719	Fe-S assembly protein
BBPR_0814	COG0396	ATPase activity
BBPR_0817	COG2151	metal-sulfur cluster biosynthetic enzyme
BBPR_0820	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBPR_0821	COG0537	adenosine 5'-monophosphoramidase activity
BBPR_0827	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BBPR_0832	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBPR_0836	COG2860	membrane
BBPR_0840	COG0436	Aminotransferase
BBPR_0842	COG0069	glutamate synthase activity
BBPR_0842	COG0067	glutamate synthase
BBPR_0842	COG0070	glutamate synthase
BBPR_0846	COG0297	glycogen (starch) synthase activity
BBPR_0847	COG1119	ATPase activity
BBPR_0848	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBPR_0868	COG1073	alpha beta
BBPR_0870	COG2062	phosphohistidine phosphatase, SixA
BBPR_0871	COG4974	Belongs to the 'phage' integrase family
BBPR_0883	COG3617	BRO family, N-terminal domain
BBPR_0891	COG1475	DNA binding
BBPR_0934	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBPR_0939	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBPR_0940	COG0284	orotidine-5'-phosphate decarboxylase activity
BBPR_0941	COG0543	2 iron, 2 sulfur cluster binding
BBPR_0942	COG0167	dihydroorotate dehydrogenase activity
BBPR_0945	COG1063	alcohol dehydrogenase
BBPR_0947	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBPR_0949	COG4221	oxidoreductase activity
BBPR_0953	COG1791	Catalyzes 2 different reactions between oxygene and the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene) depending upon the metal bound in the active site. Fe-containing acireductone dioxygenase (Fe-ARD) produces formate and 2-keto-4- methylthiobutyrate (KMTB), the alpha-ketoacid precursor of methionine in the methionine recycle pathway. Ni-containing acireductone dioxygenase (Ni-ARD) produces methylthiopropionate, carbon monoxide and formate, and does not lie on the methionine recycle pathway
BBPR_0956	COG4106	trans-aconitate 2-methyltransferase activity
BBPR_0958	COG3226	Transcriptional regulator
BBPR_0960	COG0583	DNA-binding transcription factor activity
BBPR_0970	COG1388	LysM domain
BBPR_0970	COG3942	CHAP domain
BBPR_0983	COG1803	Methylglyoxal synthase
BBPR_0998	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBPR_1001	COG0133	tryptophan synthase activity
BBPR_1004	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBPR_1009	COG0045	succinate-CoA ligase (ADP-forming) activity
BBPR_1011	COG1862	Preprotein translocase
BBPR_1021	COG1301	dicarboxylic acid transport
BBPR_1029	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBPR_1030	COG3619	membrane
BBPR_1036	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBPR_1041	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBPR_1045	COG1136	(ABC) transporter
BBPR_1045	COG0577	efflux transmembrane transporter activity
BBPR_1046	COG0745	RESPONSE REGULATOR receiver
BBPR_1047	COG2205	protein histidine kinase activity
BBPR_1048	COG1876	peptidase activity
BBPR_1049	COG0488	(ABC) transporter
BBPR_1053	COG1940	carbohydrate kinase activity
BBPR_1054	COG1940	carbohydrate kinase activity
BBPR_1056	COG0395	ABC-type sugar transport system, permease component
BBPR_1057	COG1175	transmembrane transport
BBPR_1070	COG1022	Amp-dependent synthetase and ligase
BBPR_1072	COG0516	GMP reductase activity
BBPR_1075	COG1022	Amp-dependent synthetase and ligase
BBPR_1079	COG0456	acetyltransferase
BBPR_1081	COG0802	atpase or kinase
BBPR_1086	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBPR_1087	COG0598	Magnesium transport protein CorA
BBPR_1088	COG0406	alpha-ribazole phosphatase activity
BBPR_1094	COG3189	MarR family transcriptional regulator
BBPR_1098	COG1051	belongs to the nudix hydrolase family
BBPR_1104	COG2135	peptidase activity
BBPR_1114	COG2249	NAD(P)H dehydrogenase (quinone) activity
BBPR_1127	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBPR_1133	COG1131	(ABC) transporter
BBPR_1135	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBPR_1136	COG0497	DNA recombination
BBPR_1138	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BBPR_1139	COG0569	domain protein
BBPR_1143	COG0647	UMP catabolic process
BBPR_1149	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBPR_1165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBPR_1166	COG1136	(ABC) transporter
BBPR_1167	COG0390	transport system, permease component
BBPR_1171	COG2233	PERMEase
BBPR_1175	COG0583	DNA-binding transcription factor activity
BBPR_1177	COG1442	glycosyl transferase family 8
BBPR_1177	COG1216	Glycosyl transferase, family 2
BBPR_1182	COG0242	peptide deformylase activity
BBPR_1195	COG3177	Filamentation induced by cAMP protein fic
BBPR_1196	COG0012	GTP binding
BBPR_1197	COG0436	Aminotransferase
BBPR_1199	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBPR_1200	COG0022	dehydrogenase e1 component
BBPR_1200	COG0508	dehydrogenase complex catalyzes the overall conversion of
BBPR_1201	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BBPR_1205	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBPR_1209	COG2197	response regulator
BBPR_1210	COG0671	phosphoesterase, PA-phosphatase related
BBPR_1211	COG1136	(ABC) transporter
BBPR_1211	COG0577	efflux transmembrane transporter activity
BBPR_1212	COG1136	(ABC) transporter
BBPR_1213	COG2873	o-acetylhomoserine
BBPR_1217	COG1053	succinate dehydrogenase
BBPR_1224	COG1611	Belongs to the LOG family
BBPR_1225	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BBPR_1226	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBPR_1235	COG1882	Formate acetyltransferase
BBPR_1238	COG1473	amidohydrolase
BBPR_1240	COG0561	phosphatase activity
BBPR_1247	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBPR_1252	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBPR_1253	COG1201	RNA secondary structure unwinding
BBPR_1254	COG3655	Transcriptional regulator
BBPR_1257	COG1027	Aspartate ammonia-lyase
BBPR_1258	COG0187	DNA topoisomerase II activity
BBPR_1259	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBPR_1261	COG0142	geranyltranstransferase activity
BBPR_1265	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBPR_1267	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBPR_1272	COG1396	sequence-specific DNA binding
BBPR_1273	COG1546	Belongs to the CinA family
BBPR_1273	COG1058	Belongs to the CinA family
BBPR_1274	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BBPR_1279	COG2357	RelA SpoT domain protein
BBPR_1281	COG0670	Belongs to the BI1 family
BBPR_1284	COG2197	response regulator
BBPR_1310	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBPR_1314	COG1368	sulfuric ester hydrolase activity
BBPR_1315	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BBPR_1316	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BBPR_1320	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BBPR_1321	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BBPR_1323	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BBPR_1325	COG0701	Predicted permease
BBPR_1329	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBPR_1330	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBPR_1332	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBPR_1333	COG1355	regulation of microtubule-based process
BBPR_1335	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BBPR_1338	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBPR_1339	COG0531	amino acid
BBPR_1342	COG0514	ATP-dependent DNA helicase (RecQ)
BBPR_1349	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBPR_1356	COG0395	ABC-type sugar transport system, permease component
BBPR_1363	COG1950	PFAM Membrane protein of
BBPR_1364	COG1012	belongs to the aldehyde dehydrogenase family
BBPR_1368	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBPR_1369	COG1929	Belongs to the glycerate kinase type-1 family
BBPR_1370	COG1136	(ABC) transporter
BBPR_1370	COG0577	efflux transmembrane transporter activity
BBPR_1371	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBPR_1373	COG2814	Major facilitator Superfamily
BBPR_1374	COG0667	Aldo Keto reductase
BBPR_1375	COG2176	DNA-directed DNA polymerase activity
BBPR_1377	COG0024	Methionine aminopeptidase
BBPR_1379	COG3590	peptidase
BBPR_1386	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBPR_1390	COG0366	Alpha amylase catalytic
BBPR_1392	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBPR_1393	COG0009	L-threonylcarbamoyladenylate synthase
BBPR_1399	COG4975	Glucose uptake
BBPR_1400	COG0673	inositol 2-dehydrogenase activity
BBPR_1401	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBPR_1405	COG0513	Belongs to the DEAD box helicase family
BBPR_1411	COG2873	o-acetylhomoserine
BBPR_1416	COG1940	carbohydrate kinase activity
BBPR_1417	COG0488	(ABC) transporter
BBPR_1418	COG0477	Major facilitator Superfamily
BBPR_1424	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BBPR_1431	COG2184	nucleotidyltransferase activity
BBPR_1435	COG2205	protein histidine kinase activity
BBPR_1435	COG0784	Response regulator, receiver
BBPR_1435	COG2198	Histidine kinase
BBPR_1436	COG2197	response regulator
BBPR_1439	COG1946	Acyl-CoA thioesterase
BBPR_1442	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BBPR_1443	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BBPR_1445	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBPR_1446	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BBPR_1451	COG1215	transferase activity, transferring glycosyl groups
BBPR_1453	COG1216	Glycosyl transferase, family 2
BBPR_1454	COG1454	alcohol dehydrogenase
BBPR_1456	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BBPR_1460	COG3250	beta-galactosidase activity
BBPR_1462	COG1609	Transcriptional regulator
BBPR_1463	COG2205	protein histidine kinase activity
BBPR_1466	COG1136	(ABC) transporter
BBPR_1469	COG0577	efflux transmembrane transporter activity
BBPR_1471	COG1136	(ABC) transporter
BBPR_1472	COG1687	branched-chain amino acid
BBPR_1476	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BBPR_1479	COG0589	response to stress
BBPR_1481	COG3942	CHAP domain
BBPR_1481	COG1388	LysM domain
BBPR_1484	COG5002	protein histidine kinase activity
BBPR_1485	COG0704	Plays a role in the regulation of phosphate uptake
BBPR_1489	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBPR_1490	COG2814	Major facilitator Superfamily
BBPR_1496	COG2197	response regulator
BBPR_1497	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BBPR_1498	COG0363	glucosamine-6-phosphate deaminase activity
BBPR_1505	COG1525	nuclease
BBPR_1505	COG0737	Belongs to the 5'-nucleotidase family
BBPR_1505	COG4085	toxin activity
BBPR_1506	COG1803	Methylglyoxal synthase
BBPR_1506	COG1597	lipid kinase activity
BBPR_1507	COG3711	transcriptional antiterminator
BBPR_1508	COG2190	(PTS) system
BBPR_1508	COG1263	PTS System
BBPR_1508	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBPR_1513	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBPR_1515	COG0328	RNA-DNA hybrid ribonuclease activity
BBPR_1519	COG0196	riboflavin kinase activity
BBPR_1527	COG2308	Evidence 4 Homologs of previously reported genes of
BBPR_1537	COG0201	protein transport
BBPR_1549	COG0255	Belongs to the universal ribosomal protein uL29 family
BBPR_1562	COG3527	Alpha-acetolactate decarboxylase
BBPR_1563	COG1454	alcohol dehydrogenase
BBPR_1563	COG1012	belongs to the aldehyde dehydrogenase family
BBPR_1573	COG1739	Uncharacterized protein family UPF0029
BBPR_1575	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBPR_1577	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BBPR_1578	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBPR_1581	COG0714	Associated with various cellular activities
BBPR_1587	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBPR_1595	COG2755	lipolytic protein G-D-S-L family
BBPR_1595	COG0657	acetylesterase activity
BBPR_1596	COG4409	exo-alpha-(2->6)-sialidase activity
BBPR_1598	COG2252	PERMEase
BBPR_1601	COG0581	inorganic phosphate transmembrane transporter activity
BBPR_1604	COG0745	RESPONSE REGULATOR receiver
BBPR_1605	COG5002	protein histidine kinase activity
BBPR_1607	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBPR_1610	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBPR_1615	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BBPR_1618	COG0826	peptidase U32
BBPR_1620	COG2826	transposase and inactivated derivatives, IS30 family
BBPR_1621	COG0656	L-ascorbic acid biosynthetic process
BBPR_1624	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBPR_1625	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBPR_1628	COG1704	LemA family
BBPR_1629	COG1609	Transcriptional regulator
BBPR_1639	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBPR_1640	COG4770	biotin carboxylase activity
BBPR_1641	COG1268	BioY protein
BBPR_1642	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
BBPR_1642	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
BBPR_1646	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BBPR_1653	COG0356	it plays a direct role in the translocation of protons across the membrane
BBPR_1659	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BBPR_1662	COG0745	RESPONSE REGULATOR receiver
BBPR_1664	COG0747	negative chemotaxis
BBPR_1667	COG0287	Prephenate dehydrogenase
BBPR_1667	COG1605	Chorismate mutase
BBPR_1668	COG1522	sequence-specific DNA binding
BBPR_1669	COG0436	Aminotransferase
BBPR_1679	COG1131	(ABC) transporter
BBPR_1682	COG1322	Protein conserved in bacteria
BBPR_1683	COG1937	Protein conserved in bacteria
BBPR_1688	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BBPR_1689	COG0305	Participates in initiation and elongation during chromosome replication
BBPR_1691	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BBPR_1696	COG1309	transcriptional regulator
BBPR_1697	COG1216	Glycosyl transferase, family 2
BBPR_1703	COG1132	(ABC) transporter
BBPR_1710	COG0561	phosphatase activity
BBPR_1713	COG0561	phosphatase activity
BBPR_1714	COG2723	6-phospho-beta-galactosidase activity
BBPR_1717	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
BBPR_1720	COG1609	Transcriptional regulator
BBPR_1723	COG0577	efflux transmembrane transporter activity
BBPR_1726	COG3470	protein probably involved in high-affinity Fe2 transport
BBPR_1727	COG0672	)-iron permease
BBPR_1732	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBPR_1733	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBPR_1733	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBPR_1735	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBPR_1738	COG1754	DNA topoisomerase type I activity
BBPR_1738	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBPR_1740	COG1404	Belongs to the peptidase S8 family
BBPR_1743	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBPR_1755	COG1597	lipid kinase activity
BBPR_1763	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BBPR_1764	COG0406	alpha-ribazole phosphatase activity
BBPR_1764	COG0494	nUDIX hydrolase
BBPR_1768	COG1216	Glycosyl transferase, family 2
BBPR_1773	COG0463	Glycosyl transferase, family 2
BBPR_1776	COG1136	(ABC) transporter
BBPR_1781	COG0084	hydrolase, TatD family'
BBPR_1783	COG1609	Transcriptional regulator
BBPR_1791	COG0586	Pfam SNARE associated Golgi protein
BBPR_1795	COG0789	Transcriptional regulator
BBPR_1801	COG1609	Transcriptional regulator
BBPR_1804	COG0588	phosphoglycerate mutase activity
BBPR_1806	COG0778	Nitroreductase
BBPR_1808	COG3231	kanamycin kinase activity
BBPR_1809	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BBPR_1810	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBPR_1811	COG0590	tRNA wobble adenosine to inosine editing
BBPR_1811	COG0037	tRNA processing
BBPR_1813	COG0025	NhaP-type Na H and K H
BBPR_1816	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBPR_1817	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBPR_1823	COG2826	transposase and inactivated derivatives, IS30 family
BBPR_1824	COG3842	ATPase activity
BBPR_1828	COG3583	domain protein
BBPR_1832	COG0617	tRNA 3'-terminal CCA addition
BBPR_1836	COG0492	ferredoxin-NADP+ reductase activity
BBPR_1838	COG1192	Involved in chromosome partitioning
BBPR_1840	COG1847	R3H domain protein