locus-tag	class	description
CJD48_RS00005	COG4584	PFAM Integrase catalytic
CJD48_RS00075	COG0577	efflux transmembrane transporter activity
CJD48_RS00075	COG1136	(ABC) transporter
CJD48_RS00090	COG1113	amino acid transport
CJD48_RS00095	COG3250	beta-galactosidase activity
CJD48_RS00115	COG0477	Major facilitator Superfamily
CJD48_RS00155	COG0191	fructose-bisphosphate aldolase activity
CJD48_RS00170	COG3843	relaxase mobilization nuclease domain protein
CJD48_RS00250	COG2217	Heavy metal translocating P-type atpase
CJD48_RS00260	COG0343	queuine tRNA-ribosyltransferase activity
CJD48_RS00300	COG0494	nUDIX hydrolase
CJD48_RS00320	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJD48_RS00320	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
CJD48_RS00385	COG0768	penicillin binding
CJD48_RS00440	COG2801	Transposase and inactivated derivatives
CJD48_RS00455	COG0058	SHG alpha-glucan phosphorylase activity
CJD48_RS00465	COG1132	(ABC) transporter
CJD48_RS00495	COG2814	Major facilitator Superfamily
CJD48_RS00520	COG2826	transposase and inactivated derivatives, IS30 family
CJD48_RS00525	COG1215	transferase activity, transferring glycosyl groups
CJD48_RS00580	COG1088	dTDP-glucose 4,6-dehydratase activity
CJD48_RS00605	COG1088	dTDP-glucose 4,6-dehydratase activity
CJD48_RS00625	COG0180	Tryptophanyl-tRNA synthetase
CJD48_RS00645	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CJD48_RS00665	COG0288	reversible hydration of carbon dioxide
CJD48_RS00670	COG1609	Transcriptional regulator
CJD48_RS00675	COG1253	flavin adenine dinucleotide binding
CJD48_RS00685	COG0783	Belongs to the Dps family
CJD48_RS00705	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJD48_RS00710	COG1609	Transcriptional regulator
CJD48_RS00735	COG3534	alpha-L-arabinofuranosidase
CJD48_RS00740	COG1970	mechanosensitive ion channel activity
CJD48_RS00750	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CJD48_RS00780	COG2801	Transposase and inactivated derivatives
CJD48_RS00800	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJD48_RS00805	COG0187	DNA topoisomerase II activity
CJD48_RS00820	COG0592	DNA-directed DNA polymerase activity
CJD48_RS00850	COG1847	R3H domain protein
CJD48_RS00860	COG1192	Involved in chromosome partitioning
CJD48_RS00870	COG0492	ferredoxin-NADP+ reductase activity
CJD48_RS00890	COG0617	tRNA 3'-terminal CCA addition
CJD48_RS00910	COG3583	domain protein
CJD48_RS00935	COG3842	ATPase activity
CJD48_RS00940	COG2826	transposase and inactivated derivatives, IS30 family
CJD48_RS00970	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CJD48_RS00975	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CJD48_RS00990	COG0025	NhaP-type Na H and K H
CJD48_RS01000	COG0590	tRNA wobble adenosine to inosine editing
CJD48_RS01000	COG0037	tRNA processing
CJD48_RS01005	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CJD48_RS01010	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CJD48_RS01035	COG3231	kanamycin kinase activity
CJD48_RS01065	COG0778	Nitroreductase
CJD48_RS01075	COG0588	phosphoglycerate mutase activity
CJD48_RS01085	COG1609	Transcriptional regulator
CJD48_RS01110	COG0789	Transcriptional regulator
CJD48_RS01135	COG0586	Pfam SNARE associated Golgi protein
CJD48_RS01180	COG0084	hydrolase, TatD family'
CJD48_RS01205	COG1136	(ABC) transporter
CJD48_RS01250	COG1216	Glycosyl transferase, family 2
CJD48_RS01270	COG0494	nUDIX hydrolase
CJD48_RS01270	COG0406	alpha-ribazole phosphatase activity
CJD48_RS01275	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CJD48_RS01320	COG1597	lipid kinase activity
CJD48_RS01380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJD48_RS01395	COG1404	Belongs to the peptidase S8 family
CJD48_RS01410	COG1754	DNA topoisomerase type I activity
CJD48_RS01410	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJD48_RS01420	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CJD48_RS01430	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJD48_RS01430	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
CJD48_RS01435	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CJD48_RS01465	COG0672	)-iron permease
CJD48_RS01470	COG3470	protein probably involved in high-affinity Fe2 transport
CJD48_RS01485	COG0577	efflux transmembrane transporter activity
CJD48_RS01500	COG1609	Transcriptional regulator
CJD48_RS01515	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
CJD48_RS01530	COG2723	6-phospho-beta-galactosidase activity
CJD48_RS01535	COG0561	phosphatase activity
CJD48_RS01550	COG0561	phosphatase activity
CJD48_RS01595	COG1132	(ABC) transporter
CJD48_RS01625	COG1216	Glycosyl transferase, family 2
CJD48_RS01630	COG1309	transcriptional regulator
CJD48_RS01655	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CJD48_RS01665	COG0305	Participates in initiation and elongation during chromosome replication
CJD48_RS01670	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJD48_RS01695	COG1937	Protein conserved in bacteria
CJD48_RS01700	COG1322	Protein conserved in bacteria
CJD48_RS01760	COG0436	Aminotransferase
CJD48_RS01765	COG1522	sequence-specific DNA binding
CJD48_RS01770	COG1605	Chorismate mutase
CJD48_RS01770	COG0287	Prephenate dehydrogenase
CJD48_RS01785	COG0747	negative chemotaxis
CJD48_RS01795	COG0745	RESPONSE REGULATOR receiver
CJD48_RS01810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CJD48_RS01845	COG4974	Belongs to the 'phage' integrase family
CJD48_RS01970	COG0356	it plays a direct role in the translocation of protons across the membrane
CJD48_RS02005	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CJD48_RS02025	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
CJD48_RS02025	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
CJD48_RS02030	COG1268	BioY protein
CJD48_RS02035	COG4770	biotin carboxylase activity
CJD48_RS02040	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CJD48_RS02095	COG1704	LemA family
CJD48_RS02110	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJD48_RS02115	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CJD48_RS02130	COG0656	L-ascorbic acid biosynthetic process
CJD48_RS02140	COG0826	peptidase U32
CJD48_RS02155	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJD48_RS02175	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CJD48_RS02190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CJD48_RS02200	COG5002	protein histidine kinase activity
CJD48_RS02205	COG0745	RESPONSE REGULATOR receiver
CJD48_RS02220	COG0581	inorganic phosphate transmembrane transporter activity
CJD48_RS02235	COG2252	PERMEase
CJD48_RS02245	COG4409	exo-alpha-(2->6)-sialidase activity
CJD48_RS02250	COG0657	acetylesterase activity
CJD48_RS02250	COG2755	lipolytic protein G-D-S-L family
CJD48_RS02295	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CJD48_RS02355	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CJD48_RS02360	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
CJD48_RS02370	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJD48_RS02385	COG1739	Uncharacterized protein family UPF0029
CJD48_RS02420	COG1012	belongs to the aldehyde dehydrogenase family
CJD48_RS02420	COG1454	alcohol dehydrogenase
CJD48_RS02425	COG3527	Alpha-acetolactate decarboxylase
CJD48_RS02485	COG0255	Belongs to the universal ribosomal protein uL29 family
CJD48_RS02585	COG2801	Transposase and inactivated derivatives
CJD48_RS02605	COG2308	Evidence 4 Homologs of previously reported genes of
CJD48_RS02650	COG0196	riboflavin kinase activity
CJD48_RS02675	COG0328	RNA-DNA hybrid ribonuclease activity
CJD48_RS02685	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJD48_RS02715	COG3711	transcriptional antiterminator
CJD48_RS02720	COG1597	lipid kinase activity
CJD48_RS02720	COG1803	Methylglyoxal synthase
CJD48_RS02725	COG1525	nuclease
CJD48_RS02725	COG0737	Belongs to the 5'-nucleotidase family
CJD48_RS02725	COG4085	toxin activity
CJD48_RS02765	COG0363	glucosamine-6-phosphate deaminase activity
CJD48_RS02770	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CJD48_RS02775	COG2197	response regulator
CJD48_RS02805	COG2814	Major facilitator Superfamily
CJD48_RS02815	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CJD48_RS02835	COG0704	Plays a role in the regulation of phosphate uptake
CJD48_RS02840	COG5002	protein histidine kinase activity
CJD48_RS02850	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
CJD48_RS02855	COG1388	LysM domain
CJD48_RS02855	COG3942	CHAP domain
CJD48_RS02865	COG0589	response to stress
CJD48_RS02880	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
CJD48_RS02895	COG1687	branched-chain amino acid
CJD48_RS02905	COG1136	(ABC) transporter
CJD48_RS02915	COG0577	efflux transmembrane transporter activity
CJD48_RS02935	COG1136	(ABC) transporter
CJD48_RS02950	COG0745	RESPONSE REGULATOR receiver
CJD48_RS02955	COG2205	protein histidine kinase activity
CJD48_RS02960	COG1609	Transcriptional regulator
CJD48_RS02970	COG3250	beta-galactosidase activity
CJD48_RS03000	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
CJD48_RS03025	COG1454	alcohol dehydrogenase
CJD48_RS03030	COG1216	Glycosyl transferase, family 2
CJD48_RS03040	COG1215	transferase activity, transferring glycosyl groups
CJD48_RS03065	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CJD48_RS03070	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJD48_RS03080	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
CJD48_RS03085	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
CJD48_RS03095	COG1946	Acyl-CoA thioesterase
CJD48_RS03135	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CJD48_RS03170	COG0477	Major facilitator Superfamily
CJD48_RS03175	COG0488	(ABC) transporter
CJD48_RS03180	COG1940	carbohydrate kinase activity
CJD48_RS03195	COG2873	o-acetylhomoserine
CJD48_RS03210	COG0577	efflux transmembrane transporter activity
CJD48_RS03225	COG0513	Belongs to the DEAD box helicase family
CJD48_RS03250	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CJD48_RS03255	COG0673	inositol 2-dehydrogenase activity
CJD48_RS03260	COG4975	Glucose uptake
CJD48_RS03295	COG0009	L-threonylcarbamoyladenylate synthase
CJD48_RS03300	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CJD48_RS03310	COG0366	Alpha amylase catalytic
CJD48_RS03320	COG2205	protein histidine kinase activity
CJD48_RS03335	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJD48_RS03360	COG3590	peptidase
CJD48_RS03370	COG0024	Methionine aminopeptidase
CJD48_RS03380	COG2176	DNA-directed DNA polymerase activity
CJD48_RS03385	COG0667	Aldo Keto reductase
CJD48_RS03400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CJD48_RS03405	COG0577	efflux transmembrane transporter activity
CJD48_RS03405	COG1136	(ABC) transporter
CJD48_RS03410	COG1929	Belongs to the glycerate kinase type-1 family
CJD48_RS03415	COG0446	pyridine nucleotide-disulphide oxidoreductase
CJD48_RS03435	COG1012	belongs to the aldehyde dehydrogenase family
CJD48_RS03440	COG1950	PFAM Membrane protein of
CJD48_RS03465	COG0395	ABC-type sugar transport system, permease component
CJD48_RS03500	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJD48_RS03560	COG0514	ATP-dependent DNA helicase (RecQ)
CJD48_RS03580	COG0531	amino acid
CJD48_RS03585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CJD48_RS03600	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
CJD48_RS03625	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CJD48_RS03635	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CJD48_RS03640	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CJD48_RS03660	COG0701	Predicted permease
CJD48_RS03670	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CJD48_RS03680	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CJD48_RS03685	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CJD48_RS03700	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CJD48_RS03705	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CJD48_RS03710	COG1368	sulfuric ester hydrolase activity
CJD48_RS03730	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CJD48_RS03770	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CJD48_RS03795	COG2873	o-acetylhomoserine
CJD48_RS03870	COG2197	response regulator
CJD48_RS03885	COG0670	Belongs to the BI1 family
CJD48_RS03895	COG2357	RelA SpoT domain protein
CJD48_RS03920	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CJD48_RS03925	COG1546	Belongs to the CinA family
CJD48_RS03925	COG1058	Belongs to the CinA family
CJD48_RS03930	COG1396	sequence-specific DNA binding
CJD48_RS03960	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CJD48_RS03970	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CJD48_RS03990	COG0142	geranyltranstransferase activity
CJD48_RS04000	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CJD48_RS04005	COG0187	DNA topoisomerase II activity
CJD48_RS04025	COG3655	Transcriptional regulator
CJD48_RS04030	COG1201	RNA secondary structure unwinding
CJD48_RS04035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CJD48_RS04060	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CJD48_RS04130	COG2217	Heavy metal translocating P-type atpase
CJD48_RS04170	COG3942	CHAP domain
CJD48_RS04170	COG1705	Flagellar rod assembly protein muramidase FlgJ
CJD48_RS04235	COG3843	relaxase mobilization nuclease domain protein
CJD48_RS04270	COG0551	DNA topoisomerase type I activity
CJD48_RS04270	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CJD48_RS04305	COG0489	protein tyrosine kinase activity
CJD48_RS04345	COG0561	phosphatase activity
CJD48_RS04355	COG1473	amidohydrolase
CJD48_RS04370	COG1882	Formate acetyltransferase
CJD48_RS04425	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CJD48_RS04430	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CJD48_RS04435	COG1611	Belongs to the LOG family
CJD48_RS04470	COG1053	succinate dehydrogenase
CJD48_RS04485	COG2873	o-acetylhomoserine
CJD48_RS04515	COG1136	(ABC) transporter
CJD48_RS04520	COG1136	(ABC) transporter
CJD48_RS04520	COG0577	efflux transmembrane transporter activity
CJD48_RS04525	COG0671	phosphoesterase, PA-phosphatase related
CJD48_RS04530	COG2197	response regulator
CJD48_RS04570	COG0022	dehydrogenase e1 component
CJD48_RS04570	COG0508	dehydrogenase complex catalyzes the overall conversion of
CJD48_RS04575	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CJD48_RS04585	COG0436	Aminotransferase
CJD48_RS04590	COG0012	GTP binding
CJD48_RS04835	COG3177	Filamentation induced by cAMP protein fic
CJD48_RS04900	COG0242	peptide deformylase activity
CJD48_RS04925	COG1442	glycosyl transferase family 8
CJD48_RS04925	COG1216	Glycosyl transferase, family 2
CJD48_RS04935	COG0583	DNA-binding transcription factor activity
CJD48_RS04955	COG2233	PERMEase
CJD48_RS04970	COG0390	transport system, permease component
CJD48_RS05075	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CJD48_RS05105	COG0647	UMP catabolic process
CJD48_RS05120	COG0569	domain protein
CJD48_RS05125	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
CJD48_RS05135	COG0497	DNA recombination
CJD48_RS05140	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJD48_RS05180	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CJD48_RS05255	COG2249	NAD(P)H dehydrogenase (quinone) activity
CJD48_RS05300	COG2135	peptidase activity
CJD48_RS05330	COG1051	belongs to the nudix hydrolase family
CJD48_RS05350	COG3189	MarR family transcriptional regulator
CJD48_RS05380	COG0406	alpha-ribazole phosphatase activity
CJD48_RS05385	COG0598	Magnesium transport protein CorA
CJD48_RS05390	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJD48_RS05415	COG0802	atpase or kinase
CJD48_RS05425	COG0456	acetyltransferase
CJD48_RS05445	COG1022	Amp-dependent synthetase and ligase
CJD48_RS05460	COG0516	GMP reductase activity
CJD48_RS05470	COG1022	Amp-dependent synthetase and ligase
CJD48_RS05540	COG1175	transmembrane transport
CJD48_RS05545	COG0395	ABC-type sugar transport system, permease component
CJD48_RS05555	COG1940	carbohydrate kinase activity
CJD48_RS05560	COG1940	carbohydrate kinase activity
CJD48_RS05585	COG1876	peptidase activity
CJD48_RS05590	COG2205	protein histidine kinase activity
CJD48_RS05595	COG0745	RESPONSE REGULATOR receiver
CJD48_RS05600	COG1136	(ABC) transporter
CJD48_RS05600	COG0577	efflux transmembrane transporter activity
CJD48_RS05620	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CJD48_RS05645	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CJD48_RS05655	COG0561	phosphatase activity
CJD48_RS05675	COG3619	membrane
CJD48_RS05680	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CJD48_RS05745	COG1301	dicarboxylic acid transport
CJD48_RS05780	COG1862	Preprotein translocase
CJD48_RS05790	COG0045	succinate-CoA ligase (ADP-forming) activity
CJD48_RS05815	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJD48_RS05830	COG0133	tryptophan synthase activity
CJD48_RS05845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CJD48_RS05980	COG0583	DNA-binding transcription factor activity
CJD48_RS05990	COG3226	Transcriptional regulator
CJD48_RS06000	COG4106	trans-aconitate 2-methyltransferase activity
CJD48_RS06035	COG4221	oxidoreductase activity
CJD48_RS06045	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CJD48_RS06065	COG1063	alcohol dehydrogenase
CJD48_RS06080	COG0167	dihydroorotate dehydrogenase activity
CJD48_RS06085	COG0543	2 iron, 2 sulfur cluster binding
CJD48_RS06090	COG0284	orotidine-5'-phosphate decarboxylase activity
CJD48_RS06095	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CJD48_RS06120	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CJD48_RS06130	COG2062	phosphohistidine phosphatase, SixA
CJD48_RS06140	COG1073	alpha beta
CJD48_RS06150	COG1484	DNA-dependent DNA replication
CJD48_RS06160	COG2962	Rard protein
CJD48_RS06235	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CJD48_RS06240	COG1119	ATPase activity
CJD48_RS06245	COG0297	glycogen (starch) synthase activity
CJD48_RS06260	COG0069	glutamate synthase activity
CJD48_RS06260	COG0070	glutamate synthase
CJD48_RS06260	COG0067	glutamate synthase
CJD48_RS06270	COG0436	Aminotransferase
CJD48_RS06290	COG2860	membrane
CJD48_RS06305	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJD48_RS06330	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CJD48_RS06360	COG0537	adenosine 5'-monophosphoramidase activity
CJD48_RS06365	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CJD48_RS06385	COG2151	metal-sulfur cluster biosynthetic enzyme
CJD48_RS06400	COG0396	ATPase activity
CJD48_RS06405	COG0719	Fe-S assembly protein
CJD48_RS06435	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CJD48_RS06485	COG2755	lipolytic protein G-D-S-L family
CJD48_RS06485	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CJD48_RS06515	COG2755	lipolytic protein G-D-S-L family
CJD48_RS06515	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
CJD48_RS06550	COG1335	isochorismatase
CJD48_RS06600	COG2826	transposase and inactivated derivatives, IS30 family
CJD48_RS06620	COG1131	(ABC) transporter
CJD48_RS06630	COG4585	Histidine kinase
CJD48_RS06635	COG2197	response regulator
CJD48_RS06690	COG4868	Belongs to the UPF0371 family
CJD48_RS06695	COG0280	phosphate acetyltransferase
CJD48_RS06695	COG0857	belongs to the CobB CobQ family
CJD48_RS06700	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CJD48_RS06710	COG3340	Belongs to the peptidase S51 family
CJD48_RS06715	COG4974	Belongs to the 'phage' integrase family
CJD48_RS06735	COG0494	nUDIX hydrolase
CJD48_RS06740	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CJD48_RS06760	COG3942	CHAP domain
CJD48_RS06850	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CJD48_RS06870	COG3093	addiction module antidote protein HigA
CJD48_RS06875	COG3549	Plasmid maintenance system killer
CJD48_RS06945	COG0494	nUDIX hydrolase
CJD48_RS06950	COG0469	pyruvate kinase activity
CJD48_RS06970	COG0539	negative regulation of cytoplasmic translation
CJD48_RS06985	COG1121	(ABC) transporter
CJD48_RS07010	COG0745	RESPONSE REGULATOR receiver
CJD48_RS07015	COG2205	protein histidine kinase activity
CJD48_RS07025	COG1040	competence protein
CJD48_RS07055	COG1316	TRANSCRIPTIONal
CJD48_RS07060	COG1674	ftsk spoiiie
CJD48_RS07085	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CJD48_RS07095	COG1760	l-serine dehydratase
CJD48_RS07130	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CJD48_RS07155	COG1134	teichoic acid transport
CJD48_RS07160	COG1682	transport, permease protein
CJD48_RS07190	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
CJD48_RS07215	COG1136	(ABC) transporter
CJD48_RS07235	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CJD48_RS07290	COG0582	viral genome integration into host DNA
CJD48_RS07325	COG1122	ATPase activity
CJD48_RS07350	COG2814	Major facilitator Superfamily
CJD48_RS07365	COG2326	polyphosphate kinase activity
CJD48_RS07370	COG0765	amino acid transport
CJD48_RS07375	COG0765	amino acid transport
CJD48_RS07380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CJD48_RS07385	COG1126	abc transporter atp-binding protein
CJD48_RS07400	COG2801	Transposase and inactivated derivatives
CJD48_RS07420	COG1196	nuclear chromosome segregation
CJD48_RS07445	COG1278	Cold shock
CJD48_RS07450	COG2205	protein histidine kinase activity
CJD48_RS07455	COG0745	RESPONSE REGULATOR receiver
CJD48_RS07475	COG1278	Cold shock
CJD48_RS07490	COG0714	Associated with various cellular activities
CJD48_RS07530	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CJD48_RS07560	COG4122	O-methyltransferase activity
CJD48_RS07565	COG1222	aaa ATPase
CJD48_RS07570	COG0560	Phosphoserine phosphatase
CJD48_RS07580	COG1011	Hydrolase
CJD48_RS07640	COG0708	Exodeoxyribonuclease III
CJD48_RS07680	COG0287	Prephenate dehydrogenase
CJD48_RS07695	COG1217	gtp-binding protein TYPA
CJD48_RS07700	COG1104	cysteine desulfurase activity
CJD48_RS07710	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CJD48_RS07715	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CJD48_RS07725	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CJD48_RS07755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CJD48_RS07780	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CJD48_RS07795	COG2017	converts alpha-aldose to the beta-anomer
CJD48_RS07805	COG1595	DNA-templated transcription, initiation
CJD48_RS07830	COG1794	racemase activity, acting on amino acids and derivatives
CJD48_RS07835	COG1196	nuclear chromosome segregation
CJD48_RS07840	COG0285	dihydrofolate synthase activity
CJD48_RS07850	COG0006	proline dipeptidase activity
CJD48_RS07860	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CJD48_RS07865	COG0601	transmembrane transport
CJD48_RS07955	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CJD48_RS07965	COG0768	penicillin binding
CJD48_RS07990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CJD48_RS08020	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CJD48_RS08035	COG1643	Atp-dependent helicase
CJD48_RS08120	COG0656	L-ascorbic acid biosynthetic process
CJD48_RS08130	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
CJD48_RS08135	COG4716	Myosin-crossreactive antigen
CJD48_RS08150	COG0587	DNA-directed DNA polymerase activity
CJD48_RS08155	COG1621	beta-fructofuranosidase activity
CJD48_RS08165	COG3878	Protein conserved in bacteria
CJD48_RS08220	COG0564	pseudouridine synthase activity
CJD48_RS08230	COG3942	CHAP domain
CJD48_RS08230	COG1705	Flagellar rod assembly protein muramidase FlgJ
CJD48_RS08235	COG2177	Part of the ABC transporter FtsEX involved in
CJD48_RS08240	COG2884	Cell division ATP-binding protein ftsE
CJD48_RS08245	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CJD48_RS08290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CJD48_RS08305	COG3250	beta-galactosidase activity
CJD48_RS08325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CJD48_RS08330	COG0351	phosphomethylpyrimidine kinase
CJD48_RS08350	COG3480	Lon protease (S16) C-terminal proteolytic domain
CJD48_RS08375	COG0613	PHP domain protein
CJD48_RS08385	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CJD48_RS08400	COG1132	(ABC) transporter
CJD48_RS08405	COG1132	(ABC) transporter
CJD48_RS08440	COG0602	queuosine metabolic process
CJD48_RS08445	COG1328	CTP reductase activity
CJD48_RS08445	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CJD48_RS08450	COG1570	exodeoxyribonuclease VII activity
CJD48_RS08455	COG1722	exodeoxyribonuclease VII activity
CJD48_RS08480	COG2210	Belongs to the sulfur carrier protein TusA family
CJD48_RS08495	COG0248	Ppx GppA phosphatase
CJD48_RS08500	COG0248	Ppx GppA phosphatase
CJD48_RS08530	COG1404	Belongs to the peptidase S8 family
CJD48_RS08540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CJD48_RS08605	COG0714	Associated with various cellular activities
CJD48_RS08665	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CJD48_RS08695	COG0477	Major facilitator Superfamily
CJD48_RS08700	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CJD48_RS08710	COG1349	DNA-binding transcription factor activity
CJD48_RS08715	COG0167	dihydroorotate dehydrogenase activity
CJD48_RS08720	COG1902	pentaerythritol trinitrate reductase activity
CJD48_RS08730	COG2801	Transposase and inactivated derivatives
CJD48_RS08735	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CJD48_RS08740	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CJD48_RS08745	COG0095	Lipoate-protein ligase
CJD48_RS08790	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
CJD48_RS08805	COG2814	Major facilitator Superfamily
CJD48_RS08820	COG0656	L-ascorbic acid biosynthetic process
CJD48_RS08825	COG1609	Transcriptional regulator
CJD48_RS08860	COG1609	Transcriptional regulator
CJD48_RS08865	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CJD48_RS08895	COG3775	system Galactitol-specific IIC component
CJD48_RS08910	COG1116	anion transmembrane transporter activity
CJD48_RS08965	COG0440	acetolactate synthase activity
CJD48_RS09005	COG0488	(ABC) transporter
CJD48_RS09010	COG0519	Catalyzes the synthesis of GMP from XMP
CJD48_RS09040	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CJD48_RS09055	COG1837	Belongs to the UPF0109 family
CJD48_RS09070	COG0071	Belongs to the small heat shock protein (HSP20) family
CJD48_RS09080	COG0742	ribosomal rna small subunit methyltransferase
CJD48_RS09085	COG1301	dicarboxylic acid transport
CJD48_RS09125	COG2270	Major facilitator Superfamily
CJD48_RS09130	COG0789	Transcriptional regulator
CJD48_RS09205	COG1022	Amp-dependent synthetase and ligase
CJD48_RS09230	COG0436	Aminotransferase
CJD48_RS09260	COG0179	Fumarylacetoacetate (FAA) hydrolase
CJD48_RS09310	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CJD48_RS09375	COG0366	Alpha amylase catalytic
CJD48_RS09380	COG0584	glycerophosphoryl diester phosphodiesterase
CJD48_RS09410	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CJD48_RS09420	COG0436	Aminotransferase
CJD48_RS09450	COG1530	ribonuclease E activity
CJD48_RS09455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CJD48_RS09470	COG1136	(ABC) transporter
CJD48_RS09490	COG0083	homoserine kinase activity
CJD48_RS09495	COG0460	homoserine dehydrogenase
CJD48_RS09500	COG2190	(PTS) system
CJD48_RS09500	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJD48_RS09500	COG1263	PTS System
CJD48_RS09505	COG1263	PTS System
CJD48_RS09505	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CJD48_RS09505	COG2190	(PTS) system
CJD48_RS09520	COG0584	glycerophosphoryl diester phosphodiesterase
CJD48_RS09530	COG0251	oxidation-reduction process
CJD48_RS09605	COG1309	transcriptional regulator
CJD48_RS09615	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CJD48_RS09620	COG0167	dihydroorotate dehydrogenase activity
CJD48_RS09640	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJD48_RS09695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CJD48_RS09705	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CJD48_RS09715	COG2801	Transposase and inactivated derivatives
CJD48_RS09735	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
CJD48_RS09740	COG2189	Belongs to the N(4) N(6)-methyltransferase family
CJD48_RS09825	COG1132	(ABC) transporter
CJD48_RS09835	COG1846	Transcriptional regulator
CJD48_RS09850	COG0667	Aldo Keto reductase
CJD48_RS09870	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
CJD48_RS09890	COG1484	DNA-dependent DNA replication