locus-tag	class	description
B12L_RS00010	COG0592	DNA-directed DNA polymerase activity
B12L_RS00025	COG0187	DNA topoisomerase II activity
B12L_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B12L_RS00040	COG1609	Transcriptional regulator
B12L_RS00050	COG3250	beta-galactosidase activity
B12L_RS00060	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
B12L_RS00140	COG0783	Belongs to the Dps family
B12L_RS00145	COG1253	flavin adenine dinucleotide binding
B12L_RS00210	COG5001	Diguanylate cyclase
B12L_RS00210	COG2203	Gaf domain
B12L_RS00210	COG3706	GGDEF domain
B12L_RS00210	COG4251	negative regulation of phosphorylation
B12L_RS00225	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
B12L_RS00235	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
B12L_RS00250	COG0180	Tryptophanyl-tRNA synthetase
B12L_RS00260	COG2197	response regulator
B12L_RS00280	COG0058	SHG alpha-glucan phosphorylase activity
B12L_RS00320	COG0515	serine threonine protein kinase
B12L_RS00325	COG0768	penicillin binding
B12L_RS00360	COG0071	Belongs to the small heat shock protein (HSP20) family
B12L_RS00365	COG0697	spore germination
B12L_RS00375	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
B12L_RS00380	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
B12L_RS00400	COG1216	Glycosyl transferase, family 2
B12L_RS00410	COG0494	nUDIX hydrolase
B12L_RS00430	COG0343	queuine tRNA-ribosyltransferase activity
B12L_RS00460	COG0697	spore germination
B12L_RS00465	COG0191	fructose-bisphosphate aldolase activity
B12L_RS00505	COG1609	Transcriptional regulator
B12L_RS00510	COG0477	Major facilitator Superfamily
B12L_RS00525	COG0366	Alpha amylase catalytic
B12L_RS00530	COG1609	Transcriptional regulator
B12L_RS00565	COG1175	transmembrane transport
B12L_RS00570	COG3833	ABC-type maltose transport systems, permease component
B12L_RS00585	COG1523	belongs to the glycosyl hydrolase 13 family
B12L_RS00605	COG0789	Transcriptional regulator
B12L_RS00620	COG1028	Short-chain dehydrogenase reductase Sdr
B12L_RS00625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B12L_RS00630	COG0586	Pfam SNARE associated Golgi protein
B12L_RS00675	COG1309	transcriptional regulator
B12L_RS00710	COG0527	aspartate kinase activity
B12L_RS00730	COG1940	carbohydrate kinase activity
B12L_RS00735	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
B12L_RS00745	COG0747	negative chemotaxis
B12L_RS00755	COG0444	Belongs to the ABC transporter superfamily
B12L_RS00760	COG4608	Belongs to the ABC transporter superfamily
B12L_RS00765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B12L_RS00790	COG2186	Transcriptional regulator
B12L_RS00815	COG1754	DNA topoisomerase type I activity
B12L_RS00815	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B12L_RS00825	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
B12L_RS00840	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
B12L_RS00920	COG0672	)-iron permease
B12L_RS00925	COG3470	protein probably involved in high-affinity Fe2 transport
B12L_RS00935	COG0577	efflux transmembrane transporter activity
B12L_RS00940	COG0577	efflux transmembrane transporter activity
B12L_RS00945	COG1136	(ABC) transporter
B12L_RS00975	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
B12L_RS00980	COG0363	glucosamine-6-phosphate deaminase activity
B12L_RS01010	COG1442	glycosyl transferase family 8
B12L_RS01010	COG1216	Glycosyl transferase, family 2
B12L_RS01015	COG1309	transcriptional regulator
B12L_RS01035	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
B12L_RS01045	COG0305	Participates in initiation and elongation during chromosome replication
B12L_RS01050	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B12L_RS01055	COG3442	glutamine amidotransferase
B12L_RS01070	COG1609	Transcriptional regulator
B12L_RS01080	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
B12L_RS01115	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B12L_RS01125	COG1937	Protein conserved in bacteria
B12L_RS01145	COG1131	(ABC) transporter
B12L_RS01210	COG2182	Extracellular solute-binding protein
B12L_RS01220	COG0395	ABC-type sugar transport system, permease component
B12L_RS01260	COG0745	RESPONSE REGULATOR receiver
B12L_RS01275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
B12L_RS01300	COG0356	it plays a direct role in the translocation of protons across the membrane
B12L_RS01335	COG0355	proton-transporting ATP synthase activity, rotational mechanism
B12L_RS01375	COG0251	oxidation-reduction process
B12L_RS01410	COG3842	ATPase activity
B12L_RS01425	COG1027	Aspartate ammonia-lyase
B12L_RS01440	COG0730	response to heat
B12L_RS01445	COG0641	radical SAM
B12L_RS01450	COG1609	Transcriptional regulator
B12L_RS01455	COG3119	arylsulfatase activity
B12L_RS01470	COG0395	ABC-type sugar transport system, permease component
B12L_RS01475	COG1373	ATPase (AAA superfamily
B12L_RS01480	COG3328	transposase activity
B12L_RS01495	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
B12L_RS01510	COG0475	glutathione-regulated potassium exporter activity
B12L_RS01510	COG0569	domain protein
B12L_RS01560	COG1136	(ABC) transporter
B12L_RS01570	COG1704	LemA family
B12L_RS01605	COG1837	Belongs to the UPF0109 family
B12L_RS01635	COG0519	Catalyzes the synthesis of GMP from XMP
B12L_RS01640	COG0488	(ABC) transporter
B12L_RS01645	COG1487	ribonuclease activity
B12L_RS01655	COG0440	acetolactate synthase activity
B12L_RS01695	COG0667	Aldo Keto reductase
B12L_RS01745	COG1116	anion transmembrane transporter activity
B12L_RS01765	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
B12L_RS01770	COG1609	Transcriptional regulator
B12L_RS01780	COG0477	Major facilitator Superfamily
B12L_RS01780	COG2814	Major facilitator Superfamily
B12L_RS01790	COG4988	ABC transporter
B12L_RS01805	COG1653	transport
B12L_RS01825	COG3867	Arabinogalactan endo-beta-1,4-galactanase
B12L_RS01830	COG0656	L-ascorbic acid biosynthetic process
B12L_RS01845	COG2814	Major facilitator Superfamily
B12L_RS01860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B12L_RS01870	COG2826	transposase and inactivated derivatives, IS30 family
B12L_RS01880	COG0438	transferase activity, transferring glycosyl groups
B12L_RS01895	COG0463	Glycosyl transferase, family 2
B12L_RS01900	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
B12L_RS01985	COG0489	protein tyrosine kinase activity
B12L_RS02040	COG0095	Lipoate-protein ligase
B12L_RS02045	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
B12L_RS02050	COG4499	WXG100 protein secretion system (Wss), protein YukC
B12L_RS02050	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
B12L_RS02055	COG1902	pentaerythritol trinitrate reductase activity
B12L_RS02060	COG0167	dihydroorotate dehydrogenase activity
B12L_RS02065	COG1349	DNA-binding transcription factor activity
B12L_RS02075	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
B12L_RS02095	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
B12L_RS02130	COG0714	Associated with various cellular activities
B12L_RS02145	COG0210	DNA helicase
B12L_RS02165	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
B12L_RS02190	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
B12L_RS02195	COG2884	Cell division ATP-binding protein ftsE
B12L_RS02200	COG2177	Part of the ABC transporter FtsEX involved in
B12L_RS02205	COG3942	CHAP domain
B12L_RS02205	COG1388	LysM domain
B12L_RS02230	COG1126	abc transporter atp-binding protein
B12L_RS02240	COG0564	pseudouridine synthase activity
B12L_RS02245	COG1609	Transcriptional regulator
B12L_RS02250	COG1175	transmembrane transport
B12L_RS02255	COG0395	ABC-type sugar transport system, permease component
B12L_RS02265	COG1653	transport
B12L_RS02285	COG0601	transmembrane transport
B12L_RS02290	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B12L_RS02300	COG4608	Belongs to the ABC transporter superfamily
B12L_RS02310	COG0626	cystathionine gamma-synthase activity
B12L_RS02315	COG0514	ATP-dependent DNA helicase (RecQ)
B12L_RS02330	COG0531	amino acid
B12L_RS02335	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
B12L_RS02345	COG0358	DNA primase activity
B12L_RS02360	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B12L_RS02365	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
B12L_RS02400	COG1609	Transcriptional regulator
B12L_RS02405	COG0366	Alpha amylase catalytic
B12L_RS02425	COG1136	(ABC) transporter
B12L_RS02425	COG0577	efflux transmembrane transporter activity
B12L_RS02435	COG0577	efflux transmembrane transporter activity
B12L_RS02435	COG0577	efflux transmembrane transporter activity
B12L_RS02440	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
B12L_RS02445	COG0604	alcohol dehydrogenase
B12L_RS02450	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
B12L_RS02455	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
B12L_RS02500	COG0701	Predicted permease
B12L_RS02520	COG1012	belongs to the aldehyde dehydrogenase family
B12L_RS02540	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B12L_RS02575	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
B12L_RS02590	COG0436	Aminotransferase
B12L_RS02640	COG0583	DNA-binding transcription factor activity
B12L_RS02670	COG1063	alcohol dehydrogenase
B12L_RS02685	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B12L_RS02705	COG0110	maltose O-acetyltransferase activity
B12L_RS02710	COG0110	maltose O-acetyltransferase activity
B12L_RS02740	COG2199	diguanylate cyclase activity
B12L_RS02745	COG0390	transport system, permease component
B12L_RS02750	COG0577	efflux transmembrane transporter activity
B12L_RS02750	COG1136	(ABC) transporter
B12L_RS02775	COG0284	orotidine-5'-phosphate decarboxylase activity
B12L_RS02785	COG2176	DNA-directed DNA polymerase activity
B12L_RS02805	COG0626	cystathionine gamma-synthase activity
B12L_RS02840	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
B12L_RS02920	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
B12L_RS02935	COG1122	ATPase activity
B12L_RS02975	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B12L_RS02985	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B12L_RS02990	COG4721	ABC-type cobalt transport system, permease component
B12L_RS02995	COG1122	ATPase activity
B12L_RS03005	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B12L_RS03070	COG4115	mRNA cleavage
B12L_RS03095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
B12L_RS03100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
B12L_RS03145	COG0569	domain protein
B12L_RS03160	COG0497	DNA recombination
B12L_RS03165	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
B12L_RS03215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
B12L_RS03220	COG1472	Belongs to the glycosyl hydrolase 3 family
B12L_RS03245	COG0667	Aldo Keto reductase
B12L_RS03280	COG1760	l-serine dehydratase
B12L_RS03290	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
B12L_RS03315	COG1316	TRANSCRIPTIONal
B12L_RS03355	COG2205	protein histidine kinase activity
B12L_RS03360	COG0745	RESPONSE REGULATOR receiver
B12L_RS03380	COG1108	ABC-type Mn2 Zn2 transport systems permease components
B12L_RS03385	COG1121	(ABC) transporter
B12L_RS03400	COG0539	negative regulation of cytoplasmic translation
B12L_RS03420	COG0469	pyruvate kinase activity
B12L_RS03425	COG0494	nUDIX hydrolase
B12L_RS03445	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
B12L_RS03450	COG1051	belongs to the nudix hydrolase family
B12L_RS03475	COG0519	Catalyzes the synthesis of GMP from XMP
B12L_RS03500	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
B12L_RS03505	COG0280	phosphate acetyltransferase
B12L_RS03505	COG0857	belongs to the CobB CobQ family
B12L_RS03560	COG2801	Transposase and inactivated derivatives
B12L_RS03615	COG0799	negative regulation of ribosome biogenesis
B12L_RS03620	COG0406	alpha-ribazole phosphatase activity
B12L_RS03650	COG2011	ABC-type metal ion transport system permease component
B12L_RS03655	COG1473	amidohydrolase
B12L_RS03670	COG1882	Formate acetyltransferase
B12L_RS03725	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
B12L_RS03730	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
B12L_RS03735	COG1611	Belongs to the LOG family
B12L_RS03750	COG1053	succinate dehydrogenase
B12L_RS03755	COG0758	DNA mediated transformation
B12L_RS03785	COG2873	o-acetylhomoserine
B12L_RS03790	COG1136	(ABC) transporter
B12L_RS03795	COG1136	(ABC) transporter
B12L_RS03795	COG0577	efflux transmembrane transporter activity
B12L_RS03800	COG2197	response regulator
B12L_RS03815	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
B12L_RS03820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B12L_RS03825	COG1126	abc transporter atp-binding protein
B12L_RS03830	COG0765	amino acid transport
B12L_RS03835	COG0765	amino acid transport
B12L_RS03840	COG0012	GTP binding
B12L_RS03865	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
B12L_RS03870	COG3177	Filamentation induced by cAMP protein fic
B12L_RS03915	COG1309	transcriptional regulator
B12L_RS03925	COG2814	Major facilitator Superfamily
B12L_RS03930	COG0058	SHG alpha-glucan phosphorylase activity
B12L_RS03945	COG1846	Transcriptional regulator
B12L_RS03945	COG1940	carbohydrate kinase activity
B12L_RS03960	COG0477	Major facilitator Superfamily
B12L_RS03965	COG3119	arylsulfatase activity
B12L_RS03970	COG0641	radical SAM
B12L_RS03975	COG0730	response to heat
B12L_RS04015	COG2233	PERMEase
B12L_RS04020	COG0513	Belongs to the DEAD box helicase family
B12L_RS04025	COG0366	Alpha amylase catalytic
B12L_RS04030	COG0306	phosphate transporter
B12L_RS04040	COG2197	response regulator
B12L_RS04045	COG4585	Histidine kinase
B12L_RS04055	COG1131	(ABC) transporter
B12L_RS04085	COG3340	Belongs to the peptidase S51 family
B12L_RS04090	COG1335	isochorismatase
B12L_RS04105	COG3655	Transcriptional regulator
B12L_RS04140	COG1136	(ABC) transporter
B12L_RS04150	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
B12L_RS04225	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
B12L_RS04245	COG0719	Fe-S assembly protein
B12L_RS04250	COG0396	ATPase activity
B12L_RS04255	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
B12L_RS04265	COG2151	metal-sulfur cluster biosynthetic enzyme
B12L_RS04285	COG1385	rRNA (uridine-N3-)-methyltransferase activity
B12L_RS04290	COG0537	adenosine 5'-monophosphoramidase activity
B12L_RS04315	COG1022	Amp-dependent synthetase and ligase
B12L_RS04320	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
B12L_RS04345	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
B12L_RS04355	COG2860	membrane
B12L_RS04385	COG0069	glutamate synthase activity
B12L_RS04385	COG0070	glutamate synthase
B12L_RS04385	COG0067	glutamate synthase
B12L_RS04395	COG4166	transmembrane transport
B12L_RS04410	COG0297	glycogen (starch) synthase activity
B12L_RS04415	COG1119	ATPase activity
B12L_RS04420	COG0561	phosphatase activity
B12L_RS04425	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
B12L_RS04450	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
B12L_RS04460	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
B12L_RS04480	COG0588	phosphoglycerate mutase activity
B12L_RS04490	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
B12L_RS04515	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
B12L_RS04520	COG0284	orotidine-5'-phosphate decarboxylase activity
B12L_RS04525	COG0543	2 iron, 2 sulfur cluster binding
B12L_RS04530	COG0167	dihydroorotate dehydrogenase activity
B12L_RS04550	COG0583	DNA-binding transcription factor activity
B12L_RS04565	COG0488	(ABC) transporter
B12L_RS04570	COG4221	oxidoreductase activity
B12L_RS04595	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
B12L_RS04620	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B12L_RS04640	COG0436	Aminotransferase
B12L_RS04655	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
B12L_RS04755	COG0045	succinate-CoA ligase (ADP-forming) activity
B12L_RS04775	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
B12L_RS04780	COG1187	pseudouridine synthase activity
B12L_RS04850	COG1716	ATPase activity
B12L_RS04870	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
B12L_RS04885	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B12L_RS04900	COG0133	tryptophan synthase activity
B12L_RS04915	COG0833	amino acid
B12L_RS04975	COG0833	amino acid
B12L_RS04985	COG3189	MarR family transcriptional regulator
B12L_RS05020	COG0693	protein deglycase activity
B12L_RS05030	COG0575	Belongs to the CDS family
B12L_RS05070	COG0516	GMP reductase activity
B12L_RS05150	COG4585	Histidine kinase
B12L_RS05155	COG2197	response regulator
B12L_RS05170	COG0456	acetyltransferase
B12L_RS05180	COG0802	atpase or kinase
B12L_RS05205	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B12L_RS05210	COG0598	Magnesium transport protein CorA
B12L_RS05215	COG0406	alpha-ribazole phosphatase activity
B12L_RS05275	COG0395	ABC-type sugar transport system, permease component
B12L_RS05280	COG1175	transmembrane transport
B12L_RS05285	COG1653	transport
B12L_RS05320	COG4974	Belongs to the 'phage' integrase family
B12L_RS05355	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
B12L_RS05355	COG0551	DNA topoisomerase type I activity
B12L_RS05390	COG3843	relaxase mobilization nuclease domain protein
B12L_RS05445	COG3942	CHAP domain
B12L_RS05445	COG1705	Flagellar rod assembly protein muramidase FlgJ
B12L_RS05540	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
B12L_RS05565	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
B12L_RS05580	COG2207	Transcriptional regulator
B12L_RS05590	COG1201	RNA secondary structure unwinding
B12L_RS05595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B12L_RS05605	COG0187	DNA topoisomerase II activity
B12L_RS05610	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
B12L_RS05620	COG0142	geranyltranstransferase activity
B12L_RS05640	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
B12L_RS05650	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
B12L_RS05670	COG1396	sequence-specific DNA binding
B12L_RS05675	COG1058	Belongs to the CinA family
B12L_RS05675	COG1546	Belongs to the CinA family
B12L_RS05720	COG2197	response regulator
B12L_RS05735	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B12L_RS05760	COG0708	Exodeoxyribonuclease III
B12L_RS05770	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
B12L_RS05775	COG0601	transmembrane transport
B12L_RS05780	COG4166	transmembrane transport
B12L_RS05790	COG1136	(ABC) transporter
B12L_RS05790	COG0577	efflux transmembrane transporter activity
B12L_RS05795	COG0577	efflux transmembrane transporter activity
B12L_RS05805	COG0287	Prephenate dehydrogenase
B12L_RS05820	COG1217	gtp-binding protein TYPA
B12L_RS05830	COG4591	ABC-type transport system involved in lipoprotein release permease component
B12L_RS05830	COG1136	(ABC) transporter
B12L_RS05840	COG0477	Major facilitator Superfamily
B12L_RS05855	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
B12L_RS05860	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
B12L_RS05870	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
B12L_RS05890	COG1929	Belongs to the glycerate kinase type-1 family
B12L_RS05905	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
B12L_RS05930	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
B12L_RS05940	COG2017	converts alpha-aldose to the beta-anomer
B12L_RS05945	COG2017	converts alpha-aldose to the beta-anomer
B12L_RS05955	COG1595	DNA-templated transcription, initiation
B12L_RS05975	COG1196	nuclear chromosome segregation
B12L_RS05980	COG0285	dihydrofolate synthase activity
B12L_RS05985	COG0006	proline dipeptidase activity
B12L_RS06005	COG1940	carbohydrate kinase activity
B12L_RS06010	COG1940	carbohydrate kinase activity
B12L_RS06025	COG0738	Major facilitator superfamily
B12L_RS06065	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
B12L_RS06075	COG0768	penicillin binding
B12L_RS06100	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B12L_RS06130	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
B12L_RS06140	COG1643	Atp-dependent helicase
B12L_RS06145	COG2814	Major facilitator Superfamily
B12L_RS06195	COG0656	L-ascorbic acid biosynthetic process
B12L_RS06205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B12L_RS06220	COG4948	Mandelate Racemase Muconate Lactonizing
B12L_RS06240	COG4716	Myosin-crossreactive antigen
B12L_RS06255	COG0587	DNA-directed DNA polymerase activity
B12L_RS06290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
B12L_RS06315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B12L_RS06320	COG0352	thiamine-phosphate diphosphorylase activity
B12L_RS06320	COG0351	phosphomethylpyrimidine kinase
B12L_RS06330	COG2271	Major facilitator Superfamily
B12L_RS06340	COG2197	response regulator
B12L_RS06410	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B12L_RS06415	COG2814	Major facilitator Superfamily
B12L_RS06435	COG4581	dead DEAH box helicase
B12L_RS06440	COG2326	polyphosphate kinase activity
B12L_RS06445	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
B12L_RS06450	COG1279	arginine transmembrane transporter activity
B12L_RS06460	COG0765	amino acid transport
B12L_RS06465	COG0765	amino acid transport
B12L_RS06470	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
B12L_RS06475	COG1126	abc transporter atp-binding protein
B12L_RS06495	COG1196	nuclear chromosome segregation
B12L_RS06510	COG0477	Major facilitator Superfamily
B12L_RS06525	COG0402	S-adenosylhomocysteine deaminase activity
B12L_RS06535	COG0589	response to stress
B12L_RS06545	COG1278	Cold shock
B12L_RS06550	COG2205	protein histidine kinase activity
B12L_RS06555	COG0745	RESPONSE REGULATOR receiver
B12L_RS06575	COG1278	Cold shock
B12L_RS06590	COG0714	Associated with various cellular activities
B12L_RS06635	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
B12L_RS06665	COG4122	O-methyltransferase activity
B12L_RS06670	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
B12L_RS06680	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B12L_RS06685	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B12L_RS06685	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B12L_RS06685	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
B12L_RS06700	COG1011	Hydrolase
B12L_RS06710	COG0586	Pfam SNARE associated Golgi protein
B12L_RS06715	COG0560	Phosphoserine phosphatase
B12L_RS06755	COG4974	Belongs to the 'phage' integrase family
B12L_RS06765	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
B12L_RS06770	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
B12L_RS06785	COG3842	ATPase activity
B12L_RS06795	COG1176	ABC-type spermidine putrescine transport system, permease component I
B12L_RS06800	COG1840	ABC-type Fe3 transport system, periplasmic component
B12L_RS06810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
B12L_RS06815	COG3069	C4-dicarboxylate transmembrane transporter activity
B12L_RS06835	COG1132	(ABC) transporter
B12L_RS06840	COG1132	(ABC) transporter
B12L_RS06875	COG1309	transcriptional regulator
B12L_RS06890	COG0602	queuosine metabolic process
B12L_RS06895	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
B12L_RS06895	COG1328	CTP reductase activity
B12L_RS06900	COG1570	exodeoxyribonuclease VII activity
B12L_RS06905	COG1722	exodeoxyribonuclease VII activity
B12L_RS06910	COG2249	NAD(P)H dehydrogenase (quinone) activity
B12L_RS06915	COG1022	Amp-dependent synthetase and ligase
B12L_RS06920	COG1970	mechanosensitive ion channel activity
B12L_RS06940	COG0248	Ppx GppA phosphatase
B12L_RS06945	COG0436	Aminotransferase
B12L_RS07015	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
B12L_RS07030	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
B12L_RS07035	COG0009	L-threonylcarbamoyladenylate synthase
B12L_RS07085	COG2814	Major facilitator Superfamily
B12L_RS07095	COG0242	peptide deformylase activity
B12L_RS07110	COG1940	carbohydrate kinase activity
B12L_RS07135	COG1946	Acyl-CoA thioesterase
B12L_RS07145	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
B12L_RS07160	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
B12L_RS07165	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
B12L_RS07190	COG1215	transferase activity, transferring glycosyl groups
B12L_RS07200	COG0463	Glycosyl transferase, family 2
B12L_RS07205	COG1454	alcohol dehydrogenase
B12L_RS07210	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
B12L_RS07260	COG0488	(ABC) transporter
B12L_RS07340	COG3942	CHAP domain
B12L_RS07340	COG1705	Flagellar rod assembly protein muramidase FlgJ
B12L_RS07350	COG0758	DNA mediated transformation
B12L_RS07365	COG1126	abc transporter atp-binding protein
B12L_RS07400	COG3843	relaxase mobilization nuclease domain protein
B12L_RS07420	COG1475	DNA binding
B12L_RS07450	COG3250	beta-galactosidase activity
B12L_RS07455	COG1609	Transcriptional regulator
B12L_RS07485	COG0577	efflux transmembrane transporter activity
B12L_RS07505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
B12L_RS07525	COG0589	response to stress
B12L_RS07530	COG1388	LysM domain
B12L_RS07530	COG0791	NLP P60 protein
B12L_RS07530	COG3103	Sh3 type 3 domain protein
B12L_RS07540	COG3942	CHAP domain
B12L_RS07540	COG1705	Flagellar rod assembly protein muramidase FlgJ
B12L_RS07545	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
B12L_RS07555	COG5002	protein histidine kinase activity
B12L_RS07570	COG1575	Belongs to the MenA family. Type 1 subfamily
B12L_RS07575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
B12L_RS07585	COG2814	Major facilitator Superfamily
B12L_RS07620	COG2197	response regulator
B12L_RS07640	COG0395	ABC-type sugar transport system, permease component
B12L_RS07645	COG1175	transmembrane transport
B12L_RS07665	COG1597	lipid kinase activity
B12L_RS07665	COG1803	Methylglyoxal synthase
B12L_RS07695	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
B12L_RS07700	COG0328	RNA-DNA hybrid ribonuclease activity
B12L_RS07765	COG2308	Evidence 4 Homologs of previously reported genes of
B12L_RS07865	COG0255	Belongs to the universal ribosomal protein uL29 family
B12L_RS07915	COG3527	Alpha-acetolactate decarboxylase
B12L_RS07925	COG1454	alcohol dehydrogenase
B12L_RS07925	COG1012	belongs to the aldehyde dehydrogenase family
B12L_RS07935	COG1063	alcohol dehydrogenase
B12L_RS07990	COG1739	Uncharacterized protein family UPF0029
B12L_RS07995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
B12L_RS08005	COG2723	6-phospho-beta-galactosidase activity
B12L_RS08015	COG1175	transmembrane transport
B12L_RS08025	COG1609	Transcriptional regulator
B12L_RS08055	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
B12L_RS08070	COG0531	amino acid
B12L_RS08075	COG0812	UDP-N-acetylmuramate dehydrogenase activity
B12L_RS08115	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
B12L_RS08160	COG2252	PERMEase
B12L_RS08185	COG0745	RESPONSE REGULATOR receiver
B12L_RS08190	COG5002	protein histidine kinase activity
B12L_RS08195	COG0477	Major facilitator Superfamily
B12L_RS08205	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B12L_RS08210	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
B12L_RS08225	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
B12L_RS08240	COG0826	peptidase U32
B12L_RS08250	COG0742	ribosomal rna small subunit methyltransferase
B12L_RS08265	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
B12L_RS08265	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
B12L_RS08270	COG2270	Major facilitator Superfamily
B12L_RS08275	COG0789	Transcriptional regulator
B12L_RS08345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
B12L_RS08350	COG4770	biotin carboxylase activity
B12L_RS08355	COG1268	BioY protein
B12L_RS08390	COG0250	Participates in transcription elongation, termination and antitermination
B12L_RS08395	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
B12L_RS08405	COG0436	Aminotransferase
B12L_RS08435	COG1530	ribonuclease E activity
B12L_RS08440	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
B12L_RS08450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
B12L_RS08470	COG4948	Mandelate Racemase Muconate Lactonizing
B12L_RS08475	COG1609	Transcriptional regulator
B12L_RS08505	COG0083	homoserine kinase activity
B12L_RS08510	COG0460	homoserine dehydrogenase
B12L_RS08515	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B12L_RS08515	COG2190	(PTS) system
B12L_RS08515	COG1263	PTS System
B12L_RS08520	COG2190	(PTS) system
B12L_RS08520	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B12L_RS08520	COG1263	PTS System
B12L_RS08535	COG1309	transcriptional regulator
B12L_RS08545	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
B12L_RS08550	COG0446	pyridine nucleotide-disulphide oxidoreductase
B12L_RS08560	COG0765	amino acid transport
B12L_RS08575	COG1126	abc transporter atp-binding protein
B12L_RS08580	COG0167	dihydroorotate dehydrogenase activity
B12L_RS08615	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
B12L_RS08620	COG0494	nUDIX hydrolase
B12L_RS08620	COG0406	alpha-ribazole phosphatase activity
B12L_RS08650	COG0584	glycerophosphoryl diester phosphodiesterase
B12L_RS08670	COG0179	Fumarylacetoacetate (FAA) hydrolase
B12L_RS08690	COG3311	Transcriptional regulator
B12L_RS08720	COG1172	Belongs to the binding-protein-dependent transport system permease family
B12L_RS08725	COG1172	Belongs to the binding-protein-dependent transport system permease family
B12L_RS08730	COG1129	ABC transporter
B12L_RS08740	COG1070	Carbohydrate kinase
B12L_RS08755	COG1216	Glycosyl transferase, family 2
B12L_RS08755	COG1442	glycosyl transferase family 8
B12L_RS08765	COG1368	sulfuric ester hydrolase activity
B12L_RS08770	COG1216	Glycosyl transferase, family 2
B12L_RS08770	COG0438	transferase activity, transferring glycosyl groups
B12L_RS08795	COG1088	dTDP-glucose 4,6-dehydratase activity
B12L_RS08815	COG1376	ErfK ybiS ycfS ynhG family protein
B12L_RS08825	COG1316	TRANSCRIPTIONal
B12L_RS08830	COG0577	efflux transmembrane transporter activity
B12L_RS08835	COG1129	ABC transporter
B12L_RS08855	COG0084	hydrolase, TatD family'
B12L_RS08860	COG1132	(ABC) transporter
B12L_RS08865	COG1132	(ABC) transporter
B12L_RS08890	COG4166	transmembrane transport
B12L_RS08910	COG3579	cysteine-type endopeptidase activity
B12L_RS08960	COG1846	Transcriptional regulator
B12L_RS08965	COG1113	amino acid transport
B12L_RS08975	COG1136	(ABC) transporter
B12L_RS08975	COG0577	efflux transmembrane transporter activity
B12L_RS08980	COG1113	amino acid transport
B12L_RS09000	COG1609	Transcriptional regulator
B12L_RS09005	COG2182	Extracellular solute-binding protein
B12L_RS09010	COG0588	phosphoglycerate mutase activity
B12L_RS09055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
B12L_RS09060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
B12L_RS09065	COG0366	Alpha amylase catalytic
B12L_RS09075	COG0366	Alpha amylase catalytic
B12L_RS09080	COG0395	ABC-type sugar transport system, permease component
B12L_RS09100	COG1609	Transcriptional regulator
B12L_RS09105	COG1609	Transcriptional regulator
B12L_RS09110	COG0395	ABC-type sugar transport system, permease component
B12L_RS09115	COG1175	transmembrane transport
B12L_RS09135	COG0037	tRNA processing
B12L_RS09135	COG0590	tRNA wobble adenosine to inosine editing
B12L_RS09140	COG0025	NhaP-type Na H and K H
B12L_RS09145	COG0730	response to heat
B12L_RS09170	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
B12L_RS09180	COG1263	PTS System
B12L_RS09180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B12L_RS09180	COG2190	(PTS) system
B12L_RS09185	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
B12L_RS09185	COG1263	PTS System
B12L_RS09195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
B12L_RS09235	COG1609	Transcriptional regulator
B12L_RS09240	COG1879	ABC-type sugar transport system periplasmic component
B12L_RS09250	COG1172	Belongs to the binding-protein-dependent transport system permease family
B12L_RS09260	COG2801	Transposase and inactivated derivatives
B12L_RS09260	COG3415	Transposase
B12L_RS09265	COG3842	ATPase activity
B12L_RS09270	COG2188	Transcriptional regulator
B12L_RS09285	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
B12L_RS09290	COG1215	transferase activity, transferring glycosyl groups
B12L_RS09300	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
B12L_RS09335	COG3583	domain protein
B12L_RS09355	COG0617	tRNA 3'-terminal CCA addition
B12L_RS09375	COG0492	ferredoxin-NADP+ reductase activity
B12L_RS09380	COG1475	DNA binding
B12L_RS09385	COG1192	Involved in chromosome partitioning
B12L_RS09395	COG1847	R3H domain protein