locus-tag	class	description
BB139W423_RS00015	COG0592	DNA-directed DNA polymerase activity
BB139W423_RS00030	COG0187	DNA topoisomerase II activity
BB139W423_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BB139W423_RS00045	COG1609	Transcriptional regulator
BB139W423_RS00055	COG3250	beta-galactosidase activity
BB139W423_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BB139W423_RS00100	COG0783	Belongs to the Dps family
BB139W423_RS00120	COG1609	Transcriptional regulator
BB139W423_RS00140	COG1609	Transcriptional regulator
BB139W423_RS00185	COG1609	Transcriptional regulator
BB139W423_RS00195	COG0783	Belongs to the Dps family
BB139W423_RS00200	COG1253	flavin adenine dinucleotide binding
BB139W423_RS00265	COG2203	Gaf domain
BB139W423_RS00265	COG3706	GGDEF domain
BB139W423_RS00265	COG4251	negative regulation of phosphorylation
BB139W423_RS00265	COG5001	Diguanylate cyclase
BB139W423_RS00285	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BB139W423_RS00295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BB139W423_RS00310	COG0180	Tryptophanyl-tRNA synthetase
BB139W423_RS00320	COG2197	response regulator
BB139W423_RS00340	COG0058	SHG alpha-glucan phosphorylase activity
BB139W423_RS00380	COG0515	serine threonine protein kinase
BB139W423_RS00385	COG0768	penicillin binding
BB139W423_RS00420	COG0071	Belongs to the small heat shock protein (HSP20) family
BB139W423_RS00425	COG0697	spore germination
BB139W423_RS00435	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BB139W423_RS00440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BB139W423_RS00475	COG0494	nUDIX hydrolase
BB139W423_RS00495	COG0343	queuine tRNA-ribosyltransferase activity
BB139W423_RS00525	COG0697	spore germination
BB139W423_RS00530	COG0191	fructose-bisphosphate aldolase activity
BB139W423_RS00565	COG1609	Transcriptional regulator
BB139W423_RS00570	COG0477	Major facilitator Superfamily
BB139W423_RS00590	COG0366	Alpha amylase catalytic
BB139W423_RS00595	COG1609	Transcriptional regulator
BB139W423_RS00635	COG1175	transmembrane transport
BB139W423_RS00640	COG3833	ABC-type maltose transport systems, permease component
BB139W423_RS00655	COG1523	belongs to the glycosyl hydrolase 13 family
BB139W423_RS00675	COG0789	Transcriptional regulator
BB139W423_RS00690	COG1028	Short-chain dehydrogenase reductase Sdr
BB139W423_RS00695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB139W423_RS00700	COG0586	Pfam SNARE associated Golgi protein
BB139W423_RS00745	COG1309	transcriptional regulator
BB139W423_RS00795	COG0527	aspartate kinase activity
BB139W423_RS00830	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BB139W423_RS00835	COG1176	ABC-type spermidine putrescine transport system, permease component I
BB139W423_RS00845	COG3842	ATPase activity
BB139W423_RS00885	COG1940	carbohydrate kinase activity
BB139W423_RS00890	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BB139W423_RS00900	COG0747	negative chemotaxis
BB139W423_RS00910	COG0444	Belongs to the ABC transporter superfamily
BB139W423_RS00915	COG4608	Belongs to the ABC transporter superfamily
BB139W423_RS00920	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB139W423_RS00945	COG2186	Transcriptional regulator
BB139W423_RS00980	COG1754	DNA topoisomerase type I activity
BB139W423_RS00980	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BB139W423_RS00990	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BB139W423_RS01005	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB139W423_RS01090	COG3619	membrane
BB139W423_RS01095	COG1733	regulation of RNA biosynthetic process
BB139W423_RS01100	COG2910	NAD(P)H-binding
BB139W423_RS01115	COG0477	Major facilitator Superfamily
BB139W423_RS01120	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BB139W423_RS01125	COG0604	alcohol dehydrogenase
BB139W423_RS01125	COG1028	Short-chain dehydrogenase reductase Sdr
BB139W423_RS01125	COG3321	synthase
BB139W423_RS01135	COG2977	Belongs to the P-Pant transferase superfamily
BB139W423_RS01250	COG0672	)-iron permease
BB139W423_RS01255	COG3470	protein probably involved in high-affinity Fe2 transport
BB139W423_RS01265	COG0577	efflux transmembrane transporter activity
BB139W423_RS01270	COG0577	efflux transmembrane transporter activity
BB139W423_RS01275	COG1136	(ABC) transporter
BB139W423_RS01310	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BB139W423_RS01315	COG0363	glucosamine-6-phosphate deaminase activity
BB139W423_RS01345	COG1216	Glycosyl transferase, family 2
BB139W423_RS01345	COG1442	glycosyl transferase family 8
BB139W423_RS01350	COG1309	transcriptional regulator
BB139W423_RS01370	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BB139W423_RS01380	COG0305	Participates in initiation and elongation during chromosome replication
BB139W423_RS01385	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BB139W423_RS01390	COG3442	glutamine amidotransferase
BB139W423_RS01405	COG1609	Transcriptional regulator
BB139W423_RS01425	COG2801	Transposase and inactivated derivatives
BB139W423_RS01435	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BB139W423_RS01485	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB139W423_RS01490	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB139W423_RS01495	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB139W423_RS01505	COG1937	Protein conserved in bacteria
BB139W423_RS01525	COG1131	(ABC) transporter
BB139W423_RS01600	COG2182	Extracellular solute-binding protein
BB139W423_RS01610	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS01655	COG0745	RESPONSE REGULATOR receiver
BB139W423_RS01670	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BB139W423_RS01685	COG4974	Belongs to the 'phage' integrase family
BB139W423_RS01835	COG0356	it plays a direct role in the translocation of protons across the membrane
BB139W423_RS01870	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BB139W423_RS01910	COG0251	oxidation-reduction process
BB139W423_RS01945	COG3842	ATPase activity
BB139W423_RS01960	COG1027	Aspartate ammonia-lyase
BB139W423_RS01975	COG0730	response to heat
BB139W423_RS01980	COG0641	radical SAM
BB139W423_RS01985	COG1609	Transcriptional regulator
BB139W423_RS01990	COG3119	arylsulfatase activity
BB139W423_RS02010	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS02015	COG1373	ATPase (AAA superfamily
BB139W423_RS02065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB139W423_RS02080	COG0475	glutathione-regulated potassium exporter activity
BB139W423_RS02080	COG0569	domain protein
BB139W423_RS02140	COG1136	(ABC) transporter
BB139W423_RS02150	COG1704	LemA family
BB139W423_RS02185	COG1837	Belongs to the UPF0109 family
BB139W423_RS02220	COG0505	Belongs to the CarA family
BB139W423_RS02225	COG0488	(ABC) transporter
BB139W423_RS02230	COG1487	ribonuclease activity
BB139W423_RS02240	COG0440	acetolactate synthase activity
BB139W423_RS02280	COG0667	Aldo Keto reductase
BB139W423_RS02330	COG1116	anion transmembrane transporter activity
BB139W423_RS02355	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BB139W423_RS02360	COG1609	Transcriptional regulator
BB139W423_RS02375	COG2814	Major facilitator Superfamily
BB139W423_RS02375	COG0477	Major facilitator Superfamily
BB139W423_RS02385	COG4988	ABC transporter
BB139W423_RS02400	COG1653	transport
BB139W423_RS02405	COG1175	transmembrane transport
BB139W423_RS02410	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS02425	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BB139W423_RS02435	COG0656	L-ascorbic acid biosynthetic process
BB139W423_RS02470	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BB139W423_RS02480	COG0438	transferase activity, transferring glycosyl groups
BB139W423_RS02495	COG1216	Glycosyl transferase, family 2
BB139W423_RS02495	COG1442	glycosyl transferase family 8
BB139W423_RS02500	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BB139W423_RS02510	COG1216	Glycosyl transferase, family 2
BB139W423_RS02540	COG1484	DNA-dependent DNA replication
BB139W423_RS02680	COG0489	protein tyrosine kinase activity
BB139W423_RS02740	COG0095	Lipoate-protein ligase
BB139W423_RS02745	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB139W423_RS02750	COG4499	WXG100 protein secretion system (Wss), protein YukC
BB139W423_RS02750	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB139W423_RS02755	COG1902	pentaerythritol trinitrate reductase activity
BB139W423_RS02760	COG0167	dihydroorotate dehydrogenase activity
BB139W423_RS02765	COG1349	DNA-binding transcription factor activity
BB139W423_RS02775	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BB139W423_RS02800	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BB139W423_RS02835	COG0714	Associated with various cellular activities
BB139W423_RS02850	COG0210	DNA helicase
BB139W423_RS02870	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BB139W423_RS02900	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BB139W423_RS02905	COG2884	Cell division ATP-binding protein ftsE
BB139W423_RS02910	COG2177	Part of the ABC transporter FtsEX involved in
BB139W423_RS02915	COG1388	LysM domain
BB139W423_RS02915	COG3942	CHAP domain
BB139W423_RS02940	COG1126	abc transporter atp-binding protein
BB139W423_RS02950	COG0564	pseudouridine synthase activity
BB139W423_RS02955	COG1609	Transcriptional regulator
BB139W423_RS02965	COG1175	transmembrane transport
BB139W423_RS02970	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS02980	COG1653	transport
BB139W423_RS03000	COG0601	transmembrane transport
BB139W423_RS03005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB139W423_RS03015	COG4608	Belongs to the ABC transporter superfamily
BB139W423_RS03025	COG0626	cystathionine gamma-synthase activity
BB139W423_RS03030	COG0514	ATP-dependent DNA helicase (RecQ)
BB139W423_RS03045	COG1609	Transcriptional regulator
BB139W423_RS03070	COG1175	transmembrane transport
BB139W423_RS03075	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS03095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BB139W423_RS03100	COG3265	gluconokinase activity
BB139W423_RS03105	COG4948	Mandelate Racemase Muconate Lactonizing
BB139W423_RS03110	COG0246	Mannitol dehydrogenase
BB139W423_RS03115	COG1904	glucuronate isomerase
BB139W423_RS03130	COG1609	Transcriptional regulator
BB139W423_RS03135	COG0531	amino acid
BB139W423_RS03140	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB139W423_RS03150	COG0358	DNA primase activity
BB139W423_RS03175	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB139W423_RS03180	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BB139W423_RS03215	COG1609	Transcriptional regulator
BB139W423_RS03220	COG0366	Alpha amylase catalytic
BB139W423_RS03245	COG0577	efflux transmembrane transporter activity
BB139W423_RS03245	COG1136	(ABC) transporter
BB139W423_RS03255	COG0577	efflux transmembrane transporter activity
BB139W423_RS03255	COG0577	efflux transmembrane transporter activity
BB139W423_RS03260	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BB139W423_RS03265	COG0604	alcohol dehydrogenase
BB139W423_RS03270	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BB139W423_RS03275	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BB139W423_RS03320	COG0701	Predicted permease
BB139W423_RS03340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BB139W423_RS03350	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BB139W423_RS03355	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BB139W423_RS03360	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BB139W423_RS03385	COG1012	belongs to the aldehyde dehydrogenase family
BB139W423_RS03405	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BB139W423_RS03470	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BB139W423_RS03485	COG0436	Aminotransferase
BB139W423_RS03505	COG0385	Bile acid
BB139W423_RS03540	COG0583	DNA-binding transcription factor activity
BB139W423_RS03570	COG1063	alcohol dehydrogenase
BB139W423_RS03590	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BB139W423_RS03615	COG0110	maltose O-acetyltransferase activity
BB139W423_RS03620	COG0110	maltose O-acetyltransferase activity
BB139W423_RS03650	COG0390	transport system, permease component
BB139W423_RS03655	COG0577	efflux transmembrane transporter activity
BB139W423_RS03655	COG1136	(ABC) transporter
BB139W423_RS03680	COG0284	orotidine-5'-phosphate decarboxylase activity
BB139W423_RS03690	COG2176	DNA-directed DNA polymerase activity
BB139W423_RS03710	COG0626	cystathionine gamma-synthase activity
BB139W423_RS03755	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BB139W423_RS03835	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB139W423_RS03845	COG0436	Aminotransferase
BB139W423_RS03850	COG1122	ATPase activity
BB139W423_RS03890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB139W423_RS03900	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB139W423_RS03905	COG4721	ABC-type cobalt transport system, permease component
BB139W423_RS03910	COG1122	ATPase activity
BB139W423_RS03920	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB139W423_RS03975	COG1116	anion transmembrane transporter activity
BB139W423_RS04015	COG4115	mRNA cleavage
BB139W423_RS04045	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BB139W423_RS04050	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BB139W423_RS04105	COG0497	DNA recombination
BB139W423_RS04110	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB139W423_RS04160	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BB139W423_RS04165	COG1472	Belongs to the glycosyl hydrolase 3 family
BB139W423_RS04195	COG0667	Aldo Keto reductase
BB139W423_RS04230	COG4974	Belongs to the 'phage' integrase family
BB139W423_RS04280	COG1653	transport
BB139W423_RS04285	COG1175	transmembrane transport
BB139W423_RS04290	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS04305	COG1609	Transcriptional regulator
BB139W423_RS04325	COG3177	Filamentation induced by cAMP protein fic
BB139W423_RS04360	COG1760	l-serine dehydratase
BB139W423_RS04370	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB139W423_RS04395	COG1316	TRANSCRIPTIONal
BB139W423_RS04435	COG2205	protein histidine kinase activity
BB139W423_RS04440	COG0745	RESPONSE REGULATOR receiver
BB139W423_RS04460	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BB139W423_RS04465	COG1121	(ABC) transporter
BB139W423_RS04480	COG0539	negative regulation of cytoplasmic translation
BB139W423_RS04500	COG0469	pyruvate kinase activity
BB139W423_RS04505	COG0494	nUDIX hydrolase
BB139W423_RS04525	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BB139W423_RS04530	COG1051	belongs to the nudix hydrolase family
BB139W423_RS04610	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BB139W423_RS04615	COG0857	belongs to the CobB CobQ family
BB139W423_RS04615	COG0280	phosphate acetyltransferase
BB139W423_RS04655	COG0799	negative regulation of ribosome biogenesis
BB139W423_RS04660	COG0406	alpha-ribazole phosphatase activity
BB139W423_RS04690	COG2011	ABC-type metal ion transport system permease component
BB139W423_RS04695	COG1473	amidohydrolase
BB139W423_RS04710	COG1882	Formate acetyltransferase
BB139W423_RS04770	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BB139W423_RS04775	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BB139W423_RS04780	COG1611	Belongs to the LOG family
BB139W423_RS04795	COG1053	succinate dehydrogenase
BB139W423_RS04800	COG0758	DNA mediated transformation
BB139W423_RS04830	COG2873	o-acetylhomoserine
BB139W423_RS04835	COG1136	(ABC) transporter
BB139W423_RS04840	COG0577	efflux transmembrane transporter activity
BB139W423_RS04840	COG1136	(ABC) transporter
BB139W423_RS04845	COG2197	response regulator
BB139W423_RS04860	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BB139W423_RS04865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB139W423_RS04870	COG1126	abc transporter atp-binding protein
BB139W423_RS04875	COG0765	amino acid transport
BB139W423_RS04880	COG0765	amino acid transport
BB139W423_RS04885	COG0012	GTP binding
BB139W423_RS04895	COG2814	Major facilitator Superfamily
BB139W423_RS04920	COG1846	Transcriptional regulator
BB139W423_RS04920	COG1940	carbohydrate kinase activity
BB139W423_RS04935	COG0477	Major facilitator Superfamily
BB139W423_RS04940	COG3119	arylsulfatase activity
BB139W423_RS04945	COG0641	radical SAM
BB139W423_RS04950	COG0730	response to heat
BB139W423_RS05000	COG2233	PERMEase
BB139W423_RS05005	COG0513	Belongs to the DEAD box helicase family
BB139W423_RS05010	COG0366	Alpha amylase catalytic
BB139W423_RS05015	COG0306	phosphate transporter
BB139W423_RS05025	COG2197	response regulator
BB139W423_RS05030	COG4585	Histidine kinase
BB139W423_RS05035	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB139W423_RS05040	COG1131	(ABC) transporter
BB139W423_RS05070	COG3340	Belongs to the peptidase S51 family
BB139W423_RS05075	COG1335	isochorismatase
BB139W423_RS05095	COG3655	Transcriptional regulator
BB139W423_RS05135	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BB139W423_RS05210	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BB139W423_RS05235	COG0719	Fe-S assembly protein
BB139W423_RS05240	COG0396	ATPase activity
BB139W423_RS05245	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB139W423_RS05255	COG2151	metal-sulfur cluster biosynthetic enzyme
BB139W423_RS05275	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BB139W423_RS05280	COG0537	adenosine 5'-monophosphoramidase activity
BB139W423_RS05285	COG1702	phosphate starvation-inducible protein PhoH
BB139W423_RS05305	COG1022	Amp-dependent synthetase and ligase
BB139W423_RS05310	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BB139W423_RS05335	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB139W423_RS05345	COG2860	membrane
BB139W423_RS05385	COG0070	glutamate synthase
BB139W423_RS05385	COG0069	glutamate synthase activity
BB139W423_RS05385	COG0067	glutamate synthase
BB139W423_RS05395	COG2771	luxR family
BB139W423_RS05405	COG4166	transmembrane transport
BB139W423_RS05420	COG0297	glycogen (starch) synthase activity
BB139W423_RS05425	COG1119	ATPase activity
BB139W423_RS05480	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BB139W423_RS05505	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BB139W423_RS05515	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BB139W423_RS05535	COG0588	phosphoglycerate mutase activity
BB139W423_RS05545	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BB139W423_RS05570	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BB139W423_RS05575	COG0284	orotidine-5'-phosphate decarboxylase activity
BB139W423_RS05580	COG0543	2 iron, 2 sulfur cluster binding
BB139W423_RS05585	COG0167	dihydroorotate dehydrogenase activity
BB139W423_RS05605	COG0583	DNA-binding transcription factor activity
BB139W423_RS05620	COG0488	(ABC) transporter
BB139W423_RS05625	COG4221	oxidoreductase activity
BB139W423_RS05660	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BB139W423_RS05685	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB139W423_RS05700	COG0436	Aminotransferase
BB139W423_RS05715	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BB139W423_RS05985	COG3617	BRO family, N-terminal domain
BB139W423_RS06025	COG4974	Belongs to the 'phage' integrase family
BB139W423_RS06110	COG0045	succinate-CoA ligase (ADP-forming) activity
BB139W423_RS06135	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB139W423_RS06140	COG1187	pseudouridine synthase activity
BB139W423_RS06205	COG1716	ATPase activity
BB139W423_RS06225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BB139W423_RS06240	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BB139W423_RS06255	COG0133	tryptophan synthase activity
BB139W423_RS06260	COG2135	peptidase activity
BB139W423_RS06270	COG0833	amino acid
BB139W423_RS06345	COG0745	RESPONSE REGULATOR receiver
BB139W423_RS06405	COG1131	(ABC) transporter
BB139W423_RS06435	COG1131	(ABC) transporter
BB139W423_RS06475	COG0833	amino acid
BB139W423_RS06485	COG3189	MarR family transcriptional regulator
BB139W423_RS06520	COG0693	protein deglycase activity
BB139W423_RS06530	COG0575	Belongs to the CDS family
BB139W423_RS06570	COG0516	GMP reductase activity
BB139W423_RS06605	COG3550	peptidyl-serine autophosphorylation
BB139W423_RS06650	COG4585	Histidine kinase
BB139W423_RS06655	COG2197	response regulator
BB139W423_RS06675	COG0456	acetyltransferase
BB139W423_RS06685	COG0802	atpase or kinase
BB139W423_RS06710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB139W423_RS06715	COG0598	Magnesium transport protein CorA
BB139W423_RS06720	COG0406	alpha-ribazole phosphatase activity
BB139W423_RS06780	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS06785	COG1175	transmembrane transport
BB139W423_RS06840	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB139W423_RS06865	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BB139W423_RS06880	COG1201	RNA secondary structure unwinding
BB139W423_RS06885	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB139W423_RS06895	COG0187	DNA topoisomerase II activity
BB139W423_RS06900	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB139W423_RS06910	COG0142	geranyltranstransferase activity
BB139W423_RS06930	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BB139W423_RS06940	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BB139W423_RS06965	COG1396	sequence-specific DNA binding
BB139W423_RS06970	COG1058	Belongs to the CinA family
BB139W423_RS06970	COG1546	Belongs to the CinA family
BB139W423_RS07000	COG2357	RelA SpoT domain protein
BB139W423_RS07060	COG0708	Exodeoxyribonuclease III
BB139W423_RS07070	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB139W423_RS07075	COG0601	transmembrane transport
BB139W423_RS07080	COG4166	transmembrane transport
BB139W423_RS07090	COG1136	(ABC) transporter
BB139W423_RS07090	COG0577	efflux transmembrane transporter activity
BB139W423_RS07095	COG0577	efflux transmembrane transporter activity
BB139W423_RS07105	COG0287	Prephenate dehydrogenase
BB139W423_RS07120	COG1217	gtp-binding protein TYPA
BB139W423_RS07130	COG1136	(ABC) transporter
BB139W423_RS07130	COG4591	ABC-type transport system involved in lipoprotein release permease component
BB139W423_RS07140	COG0477	Major facilitator Superfamily
BB139W423_RS07155	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BB139W423_RS07160	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BB139W423_RS07170	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BB139W423_RS07175	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BB139W423_RS07190	COG1929	Belongs to the glycerate kinase type-1 family
BB139W423_RS07195	COG2610	gluconate transmembrane transporter activity
BB139W423_RS07200	COG3835	regulator
BB139W423_RS07215	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BB139W423_RS07235	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BB139W423_RS07245	COG2017	converts alpha-aldose to the beta-anomer
BB139W423_RS07250	COG2017	converts alpha-aldose to the beta-anomer
BB139W423_RS07260	COG1595	DNA-templated transcription, initiation
BB139W423_RS07280	COG1196	nuclear chromosome segregation
BB139W423_RS07285	COG0285	dihydrofolate synthase activity
BB139W423_RS07290	COG0006	proline dipeptidase activity
BB139W423_RS07310	COG1940	carbohydrate kinase activity
BB139W423_RS07315	COG1940	carbohydrate kinase activity
BB139W423_RS07335	COG0738	Major facilitator superfamily
BB139W423_RS07380	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BB139W423_RS07390	COG0768	penicillin binding
BB139W423_RS07415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB139W423_RS07445	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BB139W423_RS07455	COG1643	Atp-dependent helicase
BB139W423_RS07460	COG2814	Major facilitator Superfamily
BB139W423_RS07510	COG0656	L-ascorbic acid biosynthetic process
BB139W423_RS07520	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB139W423_RS07560	COG4716	Myosin-crossreactive antigen
BB139W423_RS07575	COG0587	DNA-directed DNA polymerase activity
BB139W423_RS07615	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BB139W423_RS07640	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB139W423_RS07645	COG0352	thiamine-phosphate diphosphorylase activity
BB139W423_RS07645	COG0351	phosphomethylpyrimidine kinase
BB139W423_RS07660	COG2271	Major facilitator Superfamily
BB139W423_RS07670	COG2197	response regulator
BB139W423_RS07740	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BB139W423_RS07745	COG2814	Major facilitator Superfamily
BB139W423_RS07760	COG4581	dead DEAH box helicase
BB139W423_RS07765	COG2326	polyphosphate kinase activity
BB139W423_RS07770	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB139W423_RS07775	COG1279	arginine transmembrane transporter activity
BB139W423_RS07785	COG0765	amino acid transport
BB139W423_RS07790	COG0765	amino acid transport
BB139W423_RS07795	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB139W423_RS07800	COG1126	abc transporter atp-binding protein
BB139W423_RS07820	COG1196	nuclear chromosome segregation
BB139W423_RS07835	COG0477	Major facilitator Superfamily
BB139W423_RS07850	COG0589	response to stress
BB139W423_RS07860	COG1278	Cold shock
BB139W423_RS07865	COG2205	protein histidine kinase activity
BB139W423_RS07870	COG0745	RESPONSE REGULATOR receiver
BB139W423_RS07890	COG1278	Cold shock
BB139W423_RS07905	COG0714	Associated with various cellular activities
BB139W423_RS07950	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BB139W423_RS07980	COG4122	O-methyltransferase activity
BB139W423_RS07985	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BB139W423_RS07990	COG1011	Hydrolase
BB139W423_RS08000	COG0586	Pfam SNARE associated Golgi protein
BB139W423_RS08005	COG0560	Phosphoserine phosphatase
BB139W423_RS08010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BB139W423_RS08055	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB139W423_RS08060	COG1869	D-ribose catabolic process
BB139W423_RS08070	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB139W423_RS08075	COG1129	ABC transporter
BB139W423_RS08105	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB139W423_RS08110	COG1979	alcohol dehydrogenase
BB139W423_RS08115	COG0546	phosphoglycolate phosphatase activity
BB139W423_RS08125	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB139W423_RS08130	COG0135	phosphoribosylanthranilate isomerase activity
BB139W423_RS08135	COG1122	ATPase activity
BB139W423_RS08160	COG1132	(ABC) transporter
BB139W423_RS08165	COG1132	(ABC) transporter
BB139W423_RS08200	COG2211	Major facilitator Superfamily
BB139W423_RS08215	COG2211	Major facilitator Superfamily
BB139W423_RS08220	COG0745	RESPONSE REGULATOR receiver
BB139W423_RS08225	COG3850	Histidine kinase
BB139W423_RS08225	COG5002	protein histidine kinase activity
BB139W423_RS08230	COG1285	pathogenesis
BB139W423_RS08255	COG0601	transmembrane transport
BB139W423_RS08260	COG4172	Belongs to the ABC transporter superfamily
BB139W423_RS08265	COG0444	Belongs to the ABC transporter superfamily
BB139W423_RS08295	COG3940	Belongs to the glycosyl hydrolase 43 family
BB139W423_RS08310	COG0602	queuosine metabolic process
BB139W423_RS08315	COG1328	CTP reductase activity
BB139W423_RS08315	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BB139W423_RS08320	COG1570	exodeoxyribonuclease VII activity
BB139W423_RS08325	COG1722	exodeoxyribonuclease VII activity
BB139W423_RS08330	COG2249	NAD(P)H dehydrogenase (quinone) activity
BB139W423_RS08335	COG1022	Amp-dependent synthetase and ligase
BB139W423_RS08340	COG1970	mechanosensitive ion channel activity
BB139W423_RS08360	COG0248	Ppx GppA phosphatase
BB139W423_RS08365	COG0436	Aminotransferase
BB139W423_RS08435	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BB139W423_RS08450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB139W423_RS08455	COG0009	L-threonylcarbamoyladenylate synthase
BB139W423_RS08505	COG2814	Major facilitator Superfamily
BB139W423_RS08515	COG0242	peptide deformylase activity
BB139W423_RS08535	COG1940	carbohydrate kinase activity
BB139W423_RS08560	COG1946	Acyl-CoA thioesterase
BB139W423_RS08570	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BB139W423_RS08585	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB139W423_RS08590	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BB139W423_RS08615	COG1215	transferase activity, transferring glycosyl groups
BB139W423_RS08625	COG0463	Glycosyl transferase, family 2
BB139W423_RS08630	COG1454	alcohol dehydrogenase
BB139W423_RS08635	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BB139W423_RS08675	COG3250	beta-galactosidase activity
BB139W423_RS08685	COG1609	Transcriptional regulator
BB139W423_RS08720	COG0577	efflux transmembrane transporter activity
BB139W423_RS08740	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BB139W423_RS08760	COG0589	response to stress
BB139W423_RS08765	COG3103	Sh3 type 3 domain protein
BB139W423_RS08765	COG1388	LysM domain
BB139W423_RS08765	COG0791	NLP P60 protein
BB139W423_RS08775	COG1705	Flagellar rod assembly protein muramidase FlgJ
BB139W423_RS08775	COG3942	CHAP domain
BB139W423_RS08780	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BB139W423_RS08790	COG5002	protein histidine kinase activity
BB139W423_RS08805	COG1575	Belongs to the MenA family. Type 1 subfamily
BB139W423_RS08810	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BB139W423_RS08820	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS08825	COG2814	Major facilitator Superfamily
BB139W423_RS08860	COG2197	response regulator
BB139W423_RS08880	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS08885	COG1175	transmembrane transport
BB139W423_RS08905	COG1803	Methylglyoxal synthase
BB139W423_RS08905	COG1597	lipid kinase activity
BB139W423_RS08935	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB139W423_RS08940	COG0328	RNA-DNA hybrid ribonuclease activity
BB139W423_RS08965	COG0196	riboflavin kinase activity
BB139W423_RS08995	COG1609	Transcriptional regulator
BB139W423_RS09005	COG1305	Transglutaminase-like
BB139W423_RS09010	COG2308	Evidence 4 Homologs of previously reported genes of
BB139W423_RS09115	COG0255	Belongs to the universal ribosomal protein uL29 family
BB139W423_RS09165	COG3527	Alpha-acetolactate decarboxylase
BB139W423_RS09175	COG1454	alcohol dehydrogenase
BB139W423_RS09175	COG1012	belongs to the aldehyde dehydrogenase family
BB139W423_RS09215	COG1739	Uncharacterized protein family UPF0029
BB139W423_RS09220	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB139W423_RS09230	COG2723	6-phospho-beta-galactosidase activity
BB139W423_RS09240	COG1175	transmembrane transport
BB139W423_RS09250	COG1609	Transcriptional regulator
BB139W423_RS09265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BB139W423_RS09280	COG0531	amino acid
BB139W423_RS09285	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BB139W423_RS09330	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BB139W423_RS09380	COG2252	PERMEase
BB139W423_RS09405	COG0745	RESPONSE REGULATOR receiver
BB139W423_RS09410	COG5002	protein histidine kinase activity
BB139W423_RS09415	COG0477	Major facilitator Superfamily
BB139W423_RS09425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB139W423_RS09430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB139W423_RS09445	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BB139W423_RS09460	COG0826	peptidase U32
BB139W423_RS09470	COG0742	ribosomal rna small subunit methyltransferase
BB139W423_RS09485	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BB139W423_RS09485	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BB139W423_RS09490	COG2270	Major facilitator Superfamily
BB139W423_RS09600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BB139W423_RS09605	COG4770	biotin carboxylase activity
BB139W423_RS09610	COG1268	BioY protein
BB139W423_RS09645	COG0250	Participates in transcription elongation, termination and antitermination
BB139W423_RS09650	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB139W423_RS09660	COG0436	Aminotransferase
BB139W423_RS09690	COG1530	ribonuclease E activity
BB139W423_RS09695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB139W423_RS09705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB139W423_RS09730	COG4948	Mandelate Racemase Muconate Lactonizing
BB139W423_RS09735	COG1609	Transcriptional regulator
BB139W423_RS09765	COG0083	homoserine kinase activity
BB139W423_RS09770	COG0460	homoserine dehydrogenase
BB139W423_RS09775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB139W423_RS09775	COG1263	PTS System
BB139W423_RS09775	COG2190	(PTS) system
BB139W423_RS09780	COG1263	PTS System
BB139W423_RS09780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB139W423_RS09780	COG2190	(PTS) system
BB139W423_RS09795	COG1309	transcriptional regulator
BB139W423_RS09805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB139W423_RS09810	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB139W423_RS09820	COG0765	amino acid transport
BB139W423_RS09835	COG1126	abc transporter atp-binding protein
BB139W423_RS09840	COG0167	dihydroorotate dehydrogenase activity
BB139W423_RS09885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BB139W423_RS09890	COG0494	nUDIX hydrolase
BB139W423_RS09890	COG0406	alpha-ribazole phosphatase activity
BB139W423_RS09925	COG0584	glycerophosphoryl diester phosphodiesterase
BB139W423_RS09950	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB139W423_RS09975	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB139W423_RS09980	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB139W423_RS09985	COG1129	ABC transporter
BB139W423_RS09995	COG1070	Carbohydrate kinase
BB139W423_RS10010	COG1442	glycosyl transferase family 8
BB139W423_RS10010	COG1216	Glycosyl transferase, family 2
BB139W423_RS10075	COG0463	Glycosyl transferase, family 2
BB139W423_RS10090	COG1088	dTDP-glucose 4,6-dehydratase activity
BB139W423_RS10105	COG3409	Peptidoglycan-binding domain 1 protein
BB139W423_RS10105	COG3757	hydrolase, family 25
BB139W423_RS10110	COG1316	TRANSCRIPTIONal
BB139W423_RS10115	COG0577	efflux transmembrane transporter activity
BB139W423_RS10120	COG1129	ABC transporter
BB139W423_RS10145	COG0084	hydrolase, TatD family'
BB139W423_RS10150	COG1132	(ABC) transporter
BB139W423_RS10155	COG1132	(ABC) transporter
BB139W423_RS10180	COG4166	transmembrane transport
BB139W423_RS10260	COG1846	Transcriptional regulator
BB139W423_RS10295	COG1609	Transcriptional regulator
BB139W423_RS10310	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB139W423_RS10315	COG1129	ABC transporter
BB139W423_RS10355	COG3293	Transposase
BB139W423_RS10360	COG1113	amino acid transport
BB139W423_RS10370	COG0577	efflux transmembrane transporter activity
BB139W423_RS10370	COG1136	(ABC) transporter
BB139W423_RS10375	COG1113	amino acid transport
BB139W423_RS10395	COG1609	Transcriptional regulator
BB139W423_RS10405	COG0588	phosphoglycerate mutase activity
BB139W423_RS10415	COG0778	Nitroreductase
BB139W423_RS10485	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BB139W423_RS10490	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB139W423_RS10495	COG0366	Alpha amylase catalytic
BB139W423_RS10500	COG0395	ABC-type sugar transport system, permease component
BB139W423_RS10505	COG1175	transmembrane transport
BB139W423_RS10530	COG0590	tRNA wobble adenosine to inosine editing
BB139W423_RS10530	COG0037	tRNA processing
BB139W423_RS10535	COG0025	NhaP-type Na H and K H
BB139W423_RS10540	COG0730	response to heat
BB139W423_RS10565	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB139W423_RS10575	COG1263	PTS System
BB139W423_RS10575	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB139W423_RS10575	COG2190	(PTS) system
BB139W423_RS10590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB139W423_RS10625	COG1609	Transcriptional regulator
BB139W423_RS10630	COG1879	ABC-type sugar transport system periplasmic component
BB139W423_RS10640	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB139W423_RS10675	COG3842	ATPase activity
BB139W423_RS10680	COG2188	Transcriptional regulator
BB139W423_RS10695	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB139W423_RS10700	COG1215	transferase activity, transferring glycosyl groups
BB139W423_RS10710	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BB139W423_RS10735	COG1472	Belongs to the glycosyl hydrolase 3 family
BB139W423_RS10750	COG3279	Response regulator of the LytR AlgR family
BB139W423_RS10775	COG3583	domain protein
BB139W423_RS10795	COG0617	tRNA 3'-terminal CCA addition
BB139W423_RS10815	COG0492	ferredoxin-NADP+ reductase activity
BB139W423_RS10825	COG1192	Involved in chromosome partitioning
BB139W423_RS10835	COG1847	R3H domain protein