locus-tag	class	description
BB180W83_RS00015	COG0592	DNA-directed DNA polymerase activity
BB180W83_RS00030	COG0187	DNA topoisomerase II activity
BB180W83_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BB180W83_RS00045	COG1609	Transcriptional regulator
BB180W83_RS00055	COG3250	beta-galactosidase activity
BB180W83_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BB180W83_RS00100	COG0783	Belongs to the Dps family
BB180W83_RS00120	COG1609	Transcriptional regulator
BB180W83_RS00140	COG1609	Transcriptional regulator
BB180W83_RS00185	COG1609	Transcriptional regulator
BB180W83_RS00195	COG0783	Belongs to the Dps family
BB180W83_RS00200	COG1253	flavin adenine dinucleotide binding
BB180W83_RS00265	COG3706	GGDEF domain
BB180W83_RS00265	COG5001	Diguanylate cyclase
BB180W83_RS00265	COG4251	negative regulation of phosphorylation
BB180W83_RS00265	COG2203	Gaf domain
BB180W83_RS00285	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BB180W83_RS00295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BB180W83_RS00310	COG0180	Tryptophanyl-tRNA synthetase
BB180W83_RS00325	COG0058	SHG alpha-glucan phosphorylase activity
BB180W83_RS00365	COG0515	serine threonine protein kinase
BB180W83_RS00370	COG0768	penicillin binding
BB180W83_RS00405	COG0071	Belongs to the small heat shock protein (HSP20) family
BB180W83_RS00410	COG0697	spore germination
BB180W83_RS00420	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BB180W83_RS00425	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BB180W83_RS00450	COG1216	Glycosyl transferase, family 2
BB180W83_RS00460	COG0494	nUDIX hydrolase
BB180W83_RS00480	COG0343	queuine tRNA-ribosyltransferase activity
BB180W83_RS00510	COG0697	spore germination
BB180W83_RS00515	COG0191	fructose-bisphosphate aldolase activity
BB180W83_RS00550	COG1609	Transcriptional regulator
BB180W83_RS00555	COG0477	Major facilitator Superfamily
BB180W83_RS00575	COG0366	Alpha amylase catalytic
BB180W83_RS00580	COG1609	Transcriptional regulator
BB180W83_RS00620	COG1175	transmembrane transport
BB180W83_RS00625	COG3833	ABC-type maltose transport systems, permease component
BB180W83_RS00640	COG1523	belongs to the glycosyl hydrolase 13 family
BB180W83_RS00660	COG0789	Transcriptional regulator
BB180W83_RS00675	COG1028	Short-chain dehydrogenase reductase Sdr
BB180W83_RS00680	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB180W83_RS00685	COG0586	Pfam SNARE associated Golgi protein
BB180W83_RS00730	COG1309	transcriptional regulator
BB180W83_RS00790	COG0527	aspartate kinase activity
BB180W83_RS00810	COG1940	carbohydrate kinase activity
BB180W83_RS00815	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BB180W83_RS00825	COG0747	negative chemotaxis
BB180W83_RS00835	COG0444	Belongs to the ABC transporter superfamily
BB180W83_RS00840	COG4608	Belongs to the ABC transporter superfamily
BB180W83_RS00845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB180W83_RS00870	COG2186	Transcriptional regulator
BB180W83_RS00905	COG1754	DNA topoisomerase type I activity
BB180W83_RS00905	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BB180W83_RS00915	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BB180W83_RS00930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BB180W83_RS01010	COG3619	membrane
BB180W83_RS01015	COG1733	regulation of RNA biosynthetic process
BB180W83_RS01020	COG2910	NAD(P)H-binding
BB180W83_RS01035	COG0477	Major facilitator Superfamily
BB180W83_RS01055	COG2977	Belongs to the P-Pant transferase superfamily
BB180W83_RS01120	COG0672	)-iron permease
BB180W83_RS01125	COG3470	protein probably involved in high-affinity Fe2 transport
BB180W83_RS01140	COG0577	efflux transmembrane transporter activity
BB180W83_RS01145	COG1136	(ABC) transporter
BB180W83_RS01180	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BB180W83_RS01185	COG0363	glucosamine-6-phosphate deaminase activity
BB180W83_RS01215	COG1442	glycosyl transferase family 8
BB180W83_RS01215	COG1216	Glycosyl transferase, family 2
BB180W83_RS01220	COG1309	transcriptional regulator
BB180W83_RS01240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BB180W83_RS01250	COG0305	Participates in initiation and elongation during chromosome replication
BB180W83_RS01255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BB180W83_RS01260	COG3442	glutamine amidotransferase
BB180W83_RS01285	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BB180W83_RS01335	COG1131	(ABC) transporter
BB180W83_RS01370	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BB180W83_RS01380	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB180W83_RS01390	COG1937	Protein conserved in bacteria
BB180W83_RS01410	COG1131	(ABC) transporter
BB180W83_RS01490	COG2182	Extracellular solute-binding protein
BB180W83_RS01500	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS01540	COG0745	RESPONSE REGULATOR receiver
BB180W83_RS01555	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BB180W83_RS01580	COG0356	it plays a direct role in the translocation of protons across the membrane
BB180W83_RS01615	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BB180W83_RS01655	COG0251	oxidation-reduction process
BB180W83_RS01690	COG3842	ATPase activity
BB180W83_RS01705	COG1027	Aspartate ammonia-lyase
BB180W83_RS01720	COG0641	radical SAM
BB180W83_RS01725	COG1609	Transcriptional regulator
BB180W83_RS01730	COG3119	arylsulfatase activity
BB180W83_RS01750	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS01755	COG1373	ATPase (AAA superfamily
BB180W83_RS01775	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BB180W83_RS01850	COG2801	Transposase and inactivated derivatives
BB180W83_RS01855	COG1136	(ABC) transporter
BB180W83_RS01865	COG1704	LemA family
BB180W83_RS01890	COG1957	nucleoside hydrolase
BB180W83_RS01900	COG1653	transport
BB180W83_RS01905	COG1175	transmembrane transport
BB180W83_RS01910	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS01935	COG1837	Belongs to the UPF0109 family
BB180W83_RS01970	COG0505	Belongs to the CarA family
BB180W83_RS01975	COG0488	(ABC) transporter
BB180W83_RS01980	COG1487	ribonuclease activity
BB180W83_RS01990	COG0440	acetolactate synthase activity
BB180W83_RS02030	COG0667	Aldo Keto reductase
BB180W83_RS02080	COG1116	anion transmembrane transporter activity
BB180W83_RS02105	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BB180W83_RS02110	COG1609	Transcriptional regulator
BB180W83_RS02125	COG2814	Major facilitator Superfamily
BB180W83_RS02125	COG0477	Major facilitator Superfamily
BB180W83_RS02135	COG4988	ABC transporter
BB180W83_RS02150	COG1653	transport
BB180W83_RS02155	COG1175	transmembrane transport
BB180W83_RS02160	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS02175	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BB180W83_RS02185	COG0656	L-ascorbic acid biosynthetic process
BB180W83_RS02205	COG2814	Major facilitator Superfamily
BB180W83_RS02220	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BB180W83_RS02240	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BB180W83_RS02245	COG1216	Glycosyl transferase, family 2
BB180W83_RS02310	COG2801	Transposase and inactivated derivatives
BB180W83_RS02330	COG0758	DNA mediated transformation
BB180W83_RS02350	COG0489	protein tyrosine kinase activity
BB180W83_RS02410	COG0095	Lipoate-protein ligase
BB180W83_RS02415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB180W83_RS02420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BB180W83_RS02420	COG4499	WXG100 protein secretion system (Wss), protein YukC
BB180W83_RS02425	COG1902	pentaerythritol trinitrate reductase activity
BB180W83_RS02430	COG0167	dihydroorotate dehydrogenase activity
BB180W83_RS02435	COG1349	DNA-binding transcription factor activity
BB180W83_RS02445	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BB180W83_RS02470	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BB180W83_RS02505	COG0714	Associated with various cellular activities
BB180W83_RS02520	COG0210	DNA helicase
BB180W83_RS02540	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BB180W83_RS02570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BB180W83_RS02575	COG2884	Cell division ATP-binding protein ftsE
BB180W83_RS02580	COG2177	Part of the ABC transporter FtsEX involved in
BB180W83_RS02585	COG1388	LysM domain
BB180W83_RS02585	COG3942	CHAP domain
BB180W83_RS02610	COG1126	abc transporter atp-binding protein
BB180W83_RS02620	COG0564	pseudouridine synthase activity
BB180W83_RS02625	COG1609	Transcriptional regulator
BB180W83_RS02635	COG1175	transmembrane transport
BB180W83_RS02640	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS02650	COG1653	transport
BB180W83_RS02670	COG0601	transmembrane transport
BB180W83_RS02675	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB180W83_RS02685	COG4608	Belongs to the ABC transporter superfamily
BB180W83_RS02695	COG0626	cystathionine gamma-synthase activity
BB180W83_RS02700	COG0514	ATP-dependent DNA helicase (RecQ)
BB180W83_RS02715	COG0531	amino acid
BB180W83_RS02720	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BB180W83_RS02730	COG0358	DNA primase activity
BB180W83_RS02745	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB180W83_RS02750	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BB180W83_RS02785	COG1609	Transcriptional regulator
BB180W83_RS02790	COG0366	Alpha amylase catalytic
BB180W83_RS02815	COG0577	efflux transmembrane transporter activity
BB180W83_RS02815	COG1136	(ABC) transporter
BB180W83_RS02825	COG0577	efflux transmembrane transporter activity
BB180W83_RS02825	COG0577	efflux transmembrane transporter activity
BB180W83_RS02830	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BB180W83_RS02835	COG0604	alcohol dehydrogenase
BB180W83_RS02840	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BB180W83_RS02845	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BB180W83_RS02890	COG0701	Predicted permease
BB180W83_RS02920	COG1012	belongs to the aldehyde dehydrogenase family
BB180W83_RS02940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BB180W83_RS02975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BB180W83_RS02990	COG0436	Aminotransferase
BB180W83_RS03010	COG0385	Bile acid
BB180W83_RS03045	COG0583	DNA-binding transcription factor activity
BB180W83_RS03075	COG1063	alcohol dehydrogenase
BB180W83_RS03095	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BB180W83_RS03115	COG0110	maltose O-acetyltransferase activity
BB180W83_RS03155	COG1376	ErfK ybiS ycfS ynhG family protein
BB180W83_RS03160	COG0390	transport system, permease component
BB180W83_RS03165	COG1136	(ABC) transporter
BB180W83_RS03165	COG0577	efflux transmembrane transporter activity
BB180W83_RS03190	COG0284	orotidine-5'-phosphate decarboxylase activity
BB180W83_RS03200	COG2176	DNA-directed DNA polymerase activity
BB180W83_RS03220	COG0626	cystathionine gamma-synthase activity
BB180W83_RS03290	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BB180W83_RS03370	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BB180W83_RS03385	COG1122	ATPase activity
BB180W83_RS03435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB180W83_RS03440	COG4721	ABC-type cobalt transport system, permease component
BB180W83_RS03445	COG1122	ATPase activity
BB180W83_RS03455	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB180W83_RS03510	COG1116	anion transmembrane transporter activity
BB180W83_RS03540	COG4115	mRNA cleavage
BB180W83_RS03570	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BB180W83_RS03575	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BB180W83_RS03630	COG0497	DNA recombination
BB180W83_RS03635	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BB180W83_RS03685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BB180W83_RS03690	COG1472	Belongs to the glycosyl hydrolase 3 family
BB180W83_RS03695	COG2801	Transposase and inactivated derivatives
BB180W83_RS03715	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BB180W83_RS03715	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BB180W83_RS03730	COG0667	Aldo Keto reductase
BB180W83_RS03765	COG1760	l-serine dehydratase
BB180W83_RS03775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BB180W83_RS03800	COG1316	TRANSCRIPTIONal
BB180W83_RS03840	COG2205	protein histidine kinase activity
BB180W83_RS03845	COG0745	RESPONSE REGULATOR receiver
BB180W83_RS03865	COG2801	Transposase and inactivated derivatives
BB180W83_RS03875	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BB180W83_RS03880	COG1121	(ABC) transporter
BB180W83_RS03895	COG0539	negative regulation of cytoplasmic translation
BB180W83_RS03915	COG0469	pyruvate kinase activity
BB180W83_RS03920	COG0494	nUDIX hydrolase
BB180W83_RS03940	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BB180W83_RS03945	COG1051	belongs to the nudix hydrolase family
BB180W83_RS04000	COG2801	Transposase and inactivated derivatives
BB180W83_RS04005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BB180W83_RS04010	COG0280	phosphate acetyltransferase
BB180W83_RS04010	COG0857	belongs to the CobB CobQ family
BB180W83_RS04050	COG0799	negative regulation of ribosome biogenesis
BB180W83_RS04055	COG0406	alpha-ribazole phosphatase activity
BB180W83_RS04085	COG2011	ABC-type metal ion transport system permease component
BB180W83_RS04090	COG1473	amidohydrolase
BB180W83_RS04105	COG1882	Formate acetyltransferase
BB180W83_RS04165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BB180W83_RS04170	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BB180W83_RS04175	COG1611	Belongs to the LOG family
BB180W83_RS04190	COG1053	succinate dehydrogenase
BB180W83_RS04195	COG0758	DNA mediated transformation
BB180W83_RS04225	COG2873	o-acetylhomoserine
BB180W83_RS04230	COG1136	(ABC) transporter
BB180W83_RS04235	COG0577	efflux transmembrane transporter activity
BB180W83_RS04235	COG1136	(ABC) transporter
BB180W83_RS04240	COG2197	response regulator
BB180W83_RS04255	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BB180W83_RS04260	COG0012	GTP binding
BB180W83_RS04275	COG2814	Major facilitator Superfamily
BB180W83_RS04300	COG1846	Transcriptional regulator
BB180W83_RS04300	COG1940	carbohydrate kinase activity
BB180W83_RS04315	COG0477	Major facilitator Superfamily
BB180W83_RS04320	COG3119	arylsulfatase activity
BB180W83_RS04325	COG0641	radical SAM
BB180W83_RS04330	COG0730	response to heat
BB180W83_RS04370	COG2233	PERMEase
BB180W83_RS04375	COG0513	Belongs to the DEAD box helicase family
BB180W83_RS04385	COG0306	phosphate transporter
BB180W83_RS04395	COG2197	response regulator
BB180W83_RS04400	COG4585	Histidine kinase
BB180W83_RS04405	COG1131	(ABC) transporter
BB180W83_RS04435	COG3340	Belongs to the peptidase S51 family
BB180W83_RS04440	COG1335	isochorismatase
BB180W83_RS04460	COG3655	Transcriptional regulator
BB180W83_RS04500	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BB180W83_RS04580	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BB180W83_RS04605	COG0719	Fe-S assembly protein
BB180W83_RS04610	COG0396	ATPase activity
BB180W83_RS04615	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BB180W83_RS04625	COG2151	metal-sulfur cluster biosynthetic enzyme
BB180W83_RS04645	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BB180W83_RS04650	COG0537	adenosine 5'-monophosphoramidase activity
BB180W83_RS04675	COG1022	Amp-dependent synthetase and ligase
BB180W83_RS04680	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BB180W83_RS04705	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BB180W83_RS04710	COG2860	membrane
BB180W83_RS04750	COG0070	glutamate synthase
BB180W83_RS04750	COG0069	glutamate synthase activity
BB180W83_RS04750	COG0067	glutamate synthase
BB180W83_RS04760	COG4166	transmembrane transport
BB180W83_RS04775	COG0297	glycogen (starch) synthase activity
BB180W83_RS04780	COG1119	ATPase activity
BB180W83_RS04785	COG0561	phosphatase activity
BB180W83_RS04785	COG0561	phosphatase activity
BB180W83_RS04840	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BB180W83_RS04850	COG3266	domain, Protein
BB180W83_RS04850	COG0515	serine threonine protein kinase
BB180W83_RS04880	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BB180W83_RS04890	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BB180W83_RS04910	COG0588	phosphoglycerate mutase activity
BB180W83_RS04920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BB180W83_RS04945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BB180W83_RS04950	COG0284	orotidine-5'-phosphate decarboxylase activity
BB180W83_RS04955	COG0543	2 iron, 2 sulfur cluster binding
BB180W83_RS04960	COG0167	dihydroorotate dehydrogenase activity
BB180W83_RS05000	COG2801	Transposase and inactivated derivatives
BB180W83_RS05005	COG0583	DNA-binding transcription factor activity
BB180W83_RS05020	COG0488	(ABC) transporter
BB180W83_RS05025	COG4221	oxidoreductase activity
BB180W83_RS05060	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BB180W83_RS05085	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB180W83_RS05100	COG0436	Aminotransferase
BB180W83_RS05115	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BB180W83_RS05320	COG1475	DNA binding
BB180W83_RS05405	COG4974	Belongs to the 'phage' integrase family
BB180W83_RS05490	COG0045	succinate-CoA ligase (ADP-forming) activity
BB180W83_RS05515	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BB180W83_RS05520	COG1187	pseudouridine synthase activity
BB180W83_RS05585	COG1716	ATPase activity
BB180W83_RS05605	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BB180W83_RS05620	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BB180W83_RS05635	COG0133	tryptophan synthase activity
BB180W83_RS05640	COG2135	peptidase activity
BB180W83_RS05650	COG0833	amino acid
BB180W83_RS05725	COG0745	RESPONSE REGULATOR receiver
BB180W83_RS05740	COG4181	ATPase activity
BB180W83_RS05785	COG1131	(ABC) transporter
BB180W83_RS05815	COG1131	(ABC) transporter
BB180W83_RS05855	COG0833	amino acid
BB180W83_RS05865	COG3189	MarR family transcriptional regulator
BB180W83_RS05900	COG0693	protein deglycase activity
BB180W83_RS05910	COG0575	Belongs to the CDS family
BB180W83_RS05950	COG0516	GMP reductase activity
BB180W83_RS06020	COG3942	CHAP domain
BB180W83_RS06040	COG0551	DNA topoisomerase type I activity
BB180W83_RS06040	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BB180W83_RS06115	COG4585	Histidine kinase
BB180W83_RS06120	COG2197	response regulator
BB180W83_RS06140	COG0456	acetyltransferase
BB180W83_RS06150	COG0802	atpase or kinase
BB180W83_RS06175	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB180W83_RS06180	COG0598	Magnesium transport protein CorA
BB180W83_RS06185	COG0406	alpha-ribazole phosphatase activity
BB180W83_RS06245	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS06250	COG1175	transmembrane transport
BB180W83_RS06255	COG1653	transport
BB180W83_RS06325	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BB180W83_RS06350	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BB180W83_RS06365	COG2207	Transcriptional regulator
BB180W83_RS06375	COG1201	RNA secondary structure unwinding
BB180W83_RS06380	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB180W83_RS06390	COG0187	DNA topoisomerase II activity
BB180W83_RS06395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BB180W83_RS06405	COG0142	geranyltranstransferase activity
BB180W83_RS06425	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BB180W83_RS06435	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BB180W83_RS06460	COG1396	sequence-specific DNA binding
BB180W83_RS06465	COG1058	Belongs to the CinA family
BB180W83_RS06465	COG1546	Belongs to the CinA family
BB180W83_RS06495	COG2357	RelA SpoT domain protein
BB180W83_RS06525	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB180W83_RS06550	COG0708	Exodeoxyribonuclease III
BB180W83_RS06560	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BB180W83_RS06565	COG0601	transmembrane transport
BB180W83_RS06570	COG4166	transmembrane transport
BB180W83_RS06580	COG1136	(ABC) transporter
BB180W83_RS06580	COG0577	efflux transmembrane transporter activity
BB180W83_RS06585	COG0577	efflux transmembrane transporter activity
BB180W83_RS06595	COG0287	Prephenate dehydrogenase
BB180W83_RS06610	COG1217	gtp-binding protein TYPA
BB180W83_RS06620	COG1136	(ABC) transporter
BB180W83_RS06620	COG4591	ABC-type transport system involved in lipoprotein release permease component
BB180W83_RS06630	COG0477	Major facilitator Superfamily
BB180W83_RS06645	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BB180W83_RS06650	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BB180W83_RS06660	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BB180W83_RS06665	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BB180W83_RS06680	COG1929	Belongs to the glycerate kinase type-1 family
BB180W83_RS06695	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BB180W83_RS06715	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BB180W83_RS06725	COG2017	converts alpha-aldose to the beta-anomer
BB180W83_RS06730	COG2017	converts alpha-aldose to the beta-anomer
BB180W83_RS06740	COG1595	DNA-templated transcription, initiation
BB180W83_RS06760	COG1196	nuclear chromosome segregation
BB180W83_RS06765	COG0285	dihydrofolate synthase activity
BB180W83_RS06770	COG0006	proline dipeptidase activity
BB180W83_RS06790	COG1940	carbohydrate kinase activity
BB180W83_RS06795	COG1940	carbohydrate kinase activity
BB180W83_RS06810	COG0738	Major facilitator superfamily
BB180W83_RS06855	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BB180W83_RS06865	COG0768	penicillin binding
BB180W83_RS06890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB180W83_RS06920	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BB180W83_RS06930	COG1643	Atp-dependent helicase
BB180W83_RS06935	COG2814	Major facilitator Superfamily
BB180W83_RS06985	COG0656	L-ascorbic acid biosynthetic process
BB180W83_RS06995	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB180W83_RS07030	COG4716	Myosin-crossreactive antigen
BB180W83_RS07045	COG0587	DNA-directed DNA polymerase activity
BB180W83_RS07085	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BB180W83_RS07110	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB180W83_RS07115	COG0351	phosphomethylpyrimidine kinase
BB180W83_RS07115	COG0352	thiamine-phosphate diphosphorylase activity
BB180W83_RS07130	COG2271	Major facilitator Superfamily
BB180W83_RS07140	COG2197	response regulator
BB180W83_RS07210	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB180W83_RS07215	COG2814	Major facilitator Superfamily
BB180W83_RS07220	COG0745	RESPONSE REGULATOR receiver
BB180W83_RS07230	COG4581	dead DEAH box helicase
BB180W83_RS07235	COG2326	polyphosphate kinase activity
BB180W83_RS07240	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BB180W83_RS07245	COG1279	arginine transmembrane transporter activity
BB180W83_RS07255	COG0765	amino acid transport
BB180W83_RS07260	COG0765	amino acid transport
BB180W83_RS07265	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BB180W83_RS07270	COG1126	abc transporter atp-binding protein
BB180W83_RS07290	COG1196	nuclear chromosome segregation
BB180W83_RS07305	COG0477	Major facilitator Superfamily
BB180W83_RS07320	COG0589	response to stress
BB180W83_RS07330	COG1278	Cold shock
BB180W83_RS07335	COG2205	protein histidine kinase activity
BB180W83_RS07340	COG0745	RESPONSE REGULATOR receiver
BB180W83_RS07360	COG1278	Cold shock
BB180W83_RS07375	COG0714	Associated with various cellular activities
BB180W83_RS07420	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BB180W83_RS07450	COG4122	O-methyltransferase activity
BB180W83_RS07455	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BB180W83_RS07460	COG1011	Hydrolase
BB180W83_RS07470	COG0586	Pfam SNARE associated Golgi protein
BB180W83_RS07475	COG0560	Phosphoserine phosphatase
BB180W83_RS07480	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BB180W83_RS07525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB180W83_RS07530	COG1869	D-ribose catabolic process
BB180W83_RS07540	COG1172	Belongs to the binding-protein-dependent transport system permease family
BB180W83_RS07545	COG1129	ABC transporter
BB180W83_RS07575	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB180W83_RS07580	COG1979	alcohol dehydrogenase
BB180W83_RS07585	COG0546	phosphoglycolate phosphatase activity
BB180W83_RS07595	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BB180W83_RS07600	COG0135	phosphoribosylanthranilate isomerase activity
BB180W83_RS07605	COG1122	ATPase activity
BB180W83_RS07630	COG1132	(ABC) transporter
BB180W83_RS07635	COG1132	(ABC) transporter
BB180W83_RS07670	COG2211	Major facilitator Superfamily
BB180W83_RS07685	COG2211	Major facilitator Superfamily
BB180W83_RS07690	COG0745	RESPONSE REGULATOR receiver
BB180W83_RS07695	COG3850	Histidine kinase
BB180W83_RS07695	COG5002	protein histidine kinase activity
BB180W83_RS07700	COG1285	pathogenesis
BB180W83_RS07725	COG0601	transmembrane transport
BB180W83_RS07730	COG4172	Belongs to the ABC transporter superfamily
BB180W83_RS07735	COG0444	Belongs to the ABC transporter superfamily
BB180W83_RS07765	COG3940	Belongs to the glycosyl hydrolase 43 family
BB180W83_RS07780	COG0602	queuosine metabolic process
BB180W83_RS07785	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BB180W83_RS07785	COG1328	CTP reductase activity
BB180W83_RS07790	COG1570	exodeoxyribonuclease VII activity
BB180W83_RS07795	COG1722	exodeoxyribonuclease VII activity
BB180W83_RS07800	COG2249	NAD(P)H dehydrogenase (quinone) activity
BB180W83_RS07805	COG1022	Amp-dependent synthetase and ligase
BB180W83_RS07810	COG1970	mechanosensitive ion channel activity
BB180W83_RS07830	COG0248	Ppx GppA phosphatase
BB180W83_RS07835	COG0436	Aminotransferase
BB180W83_RS07905	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BB180W83_RS07920	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BB180W83_RS07925	COG0009	L-threonylcarbamoyladenylate synthase
BB180W83_RS07985	COG0242	peptide deformylase activity
BB180W83_RS08005	COG1940	carbohydrate kinase activity
BB180W83_RS08030	COG1946	Acyl-CoA thioesterase
BB180W83_RS08040	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BB180W83_RS08055	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BB180W83_RS08060	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BB180W83_RS08085	COG1215	transferase activity, transferring glycosyl groups
BB180W83_RS08095	COG0463	Glycosyl transferase, family 2
BB180W83_RS08100	COG1454	alcohol dehydrogenase
BB180W83_RS08105	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BB180W83_RS08145	COG3250	beta-galactosidase activity
BB180W83_RS08155	COG1609	Transcriptional regulator
BB180W83_RS08190	COG0577	efflux transmembrane transporter activity
BB180W83_RS08210	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BB180W83_RS08230	COG0589	response to stress
BB180W83_RS08235	COG3103	Sh3 type 3 domain protein
BB180W83_RS08235	COG0791	NLP P60 protein
BB180W83_RS08235	COG1388	LysM domain
BB180W83_RS08245	COG3942	CHAP domain
BB180W83_RS08245	COG1705	Flagellar rod assembly protein muramidase FlgJ
BB180W83_RS08260	COG5002	protein histidine kinase activity
BB180W83_RS08275	COG1575	Belongs to the MenA family. Type 1 subfamily
BB180W83_RS08280	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BB180W83_RS08295	COG2814	Major facilitator Superfamily
BB180W83_RS08330	COG2197	response regulator
BB180W83_RS08350	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS08355	COG1175	transmembrane transport
BB180W83_RS08375	COG1597	lipid kinase activity
BB180W83_RS08375	COG1803	Methylglyoxal synthase
BB180W83_RS08405	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BB180W83_RS08410	COG0328	RNA-DNA hybrid ribonuclease activity
BB180W83_RS08435	COG0196	riboflavin kinase activity
BB180W83_RS08480	COG2308	Evidence 4 Homologs of previously reported genes of
BB180W83_RS08585	COG0255	Belongs to the universal ribosomal protein uL29 family
BB180W83_RS08635	COG3527	Alpha-acetolactate decarboxylase
BB180W83_RS08645	COG1454	alcohol dehydrogenase
BB180W83_RS08645	COG1012	belongs to the aldehyde dehydrogenase family
BB180W83_RS08655	COG1063	alcohol dehydrogenase
BB180W83_RS08710	COG1739	Uncharacterized protein family UPF0029
BB180W83_RS08715	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BB180W83_RS08725	COG2723	6-phospho-beta-galactosidase activity
BB180W83_RS08735	COG1175	transmembrane transport
BB180W83_RS08745	COG1609	Transcriptional regulator
BB180W83_RS08755	COG2801	Transposase and inactivated derivatives
BB180W83_RS08770	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BB180W83_RS08785	COG0531	amino acid
BB180W83_RS08790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BB180W83_RS08835	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BB180W83_RS08885	COG2252	PERMEase
BB180W83_RS08910	COG0745	RESPONSE REGULATOR receiver
BB180W83_RS08915	COG5002	protein histidine kinase activity
BB180W83_RS08920	COG0477	Major facilitator Superfamily
BB180W83_RS08930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB180W83_RS08935	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BB180W83_RS08950	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BB180W83_RS08965	COG0826	peptidase U32
BB180W83_RS08975	COG0742	ribosomal rna small subunit methyltransferase
BB180W83_RS08990	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BB180W83_RS08990	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BB180W83_RS08995	COG2270	Major facilitator Superfamily
BB180W83_RS09095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BB180W83_RS09100	COG4770	biotin carboxylase activity
BB180W83_RS09105	COG1268	BioY protein
BB180W83_RS09145	COG0250	Participates in transcription elongation, termination and antitermination
BB180W83_RS09150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BB180W83_RS09160	COG0436	Aminotransferase
BB180W83_RS09190	COG1530	ribonuclease E activity
BB180W83_RS09195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BB180W83_RS09205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BB180W83_RS09230	COG4948	Mandelate Racemase Muconate Lactonizing
BB180W83_RS09235	COG1609	Transcriptional regulator
BB180W83_RS09265	COG0083	homoserine kinase activity
BB180W83_RS09270	COG0460	homoserine dehydrogenase
BB180W83_RS09275	COG1263	PTS System
BB180W83_RS09275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB180W83_RS09275	COG2190	(PTS) system
BB180W83_RS09280	COG2190	(PTS) system
BB180W83_RS09280	COG1263	PTS System
BB180W83_RS09280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB180W83_RS09285	COG0019	diaminopimelate decarboxylase activity
BB180W83_RS09295	COG1309	transcriptional regulator
BB180W83_RS09305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BB180W83_RS09310	COG0446	pyridine nucleotide-disulphide oxidoreductase
BB180W83_RS09320	COG0765	amino acid transport
BB180W83_RS09335	COG1126	abc transporter atp-binding protein
BB180W83_RS09340	COG0167	dihydroorotate dehydrogenase activity
BB180W83_RS09385	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BB180W83_RS09390	COG0494	nUDIX hydrolase
BB180W83_RS09390	COG0406	alpha-ribazole phosphatase activity
BB180W83_RS09425	COG0584	glycerophosphoryl diester phosphodiesterase
BB180W83_RS09450	COG0179	Fumarylacetoacetate (FAA) hydrolase
BB180W83_RS09475	COG1216	Glycosyl transferase, family 2
BB180W83_RS09475	COG1442	glycosyl transferase family 8
BB180W83_RS09485	COG1368	sulfuric ester hydrolase activity
BB180W83_RS09490	COG1368	sulfuric ester hydrolase activity
BB180W83_RS09515	COG1216	Glycosyl transferase, family 2
BB180W83_RS09530	COG1088	dTDP-glucose 4,6-dehydratase activity
BB180W83_RS09550	COG1316	TRANSCRIPTIONal
BB180W83_RS09555	COG0577	efflux transmembrane transporter activity
BB180W83_RS09560	COG1129	ABC transporter
BB180W83_RS09585	COG0084	hydrolase, TatD family'
BB180W83_RS09590	COG1132	(ABC) transporter
BB180W83_RS09595	COG1132	(ABC) transporter
BB180W83_RS09615	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS09620	COG1175	transmembrane transport
BB180W83_RS09630	COG1609	Transcriptional regulator
BB180W83_RS09635	COG1874	Beta-galactosidase
BB180W83_RS09725	COG1846	Transcriptional regulator
BB180W83_RS09740	COG1113	amino acid transport
BB180W83_RS09750	COG1136	(ABC) transporter
BB180W83_RS09750	COG0577	efflux transmembrane transporter activity
BB180W83_RS09755	COG1113	amino acid transport
BB180W83_RS09775	COG1609	Transcriptional regulator
BB180W83_RS09785	COG0588	phosphoglycerate mutase activity
BB180W83_RS09860	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BB180W83_RS09865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BB180W83_RS09870	COG0366	Alpha amylase catalytic
BB180W83_RS09875	COG0395	ABC-type sugar transport system, permease component
BB180W83_RS09880	COG1175	transmembrane transport
BB180W83_RS09905	COG0590	tRNA wobble adenosine to inosine editing
BB180W83_RS09905	COG0037	tRNA processing
BB180W83_RS09910	COG0025	NhaP-type Na H and K H
BB180W83_RS09915	COG0730	response to heat
BB180W83_RS09940	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BB180W83_RS09950	COG1263	PTS System
BB180W83_RS09950	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB180W83_RS09950	COG2190	(PTS) system
BB180W83_RS09955	COG1263	PTS System
BB180W83_RS09955	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BB180W83_RS09965	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BB180W83_RS09995	COG3842	ATPase activity
BB180W83_RS10000	COG2188	Transcriptional regulator
BB180W83_RS10015	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BB180W83_RS10020	COG1215	transferase activity, transferring glycosyl groups
BB180W83_RS10030	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BB180W83_RS10055	COG1472	Belongs to the glycosyl hydrolase 3 family
BB180W83_RS10065	COG3279	Response regulator of the LytR AlgR family
BB180W83_RS10090	COG3583	domain protein
BB180W83_RS10110	COG0617	tRNA 3'-terminal CCA addition
BB180W83_RS10130	COG0492	ferredoxin-NADP+ reductase activity
BB180W83_RS10140	COG1192	Involved in chromosome partitioning
BB180W83_RS10150	COG1847	R3H domain protein