locus-tag	class	description
CNCMI4321_RS00015	COG0592	DNA-directed DNA polymerase activity
CNCMI4321_RS00030	COG0187	DNA topoisomerase II activity
CNCMI4321_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CNCMI4321_RS00045	COG1609	Transcriptional regulator
CNCMI4321_RS00055	COG3250	beta-galactosidase activity
CNCMI4321_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
CNCMI4321_RS00145	COG0783	Belongs to the Dps family
CNCMI4321_RS00150	COG1253	flavin adenine dinucleotide binding
CNCMI4321_RS00215	COG4251	negative regulation of phosphorylation
CNCMI4321_RS00215	COG3706	GGDEF domain
CNCMI4321_RS00215	COG2203	Gaf domain
CNCMI4321_RS00215	COG5001	Diguanylate cyclase
CNCMI4321_RS00235	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
CNCMI4321_RS00245	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
CNCMI4321_RS00260	COG0180	Tryptophanyl-tRNA synthetase
CNCMI4321_RS00275	COG0058	SHG alpha-glucan phosphorylase activity
CNCMI4321_RS00315	COG0515	serine threonine protein kinase
CNCMI4321_RS00320	COG0768	penicillin binding
CNCMI4321_RS00355	COG0071	Belongs to the small heat shock protein (HSP20) family
CNCMI4321_RS00360	COG0697	spore germination
CNCMI4321_RS00370	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
CNCMI4321_RS00375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
CNCMI4321_RS00400	COG1216	Glycosyl transferase, family 2
CNCMI4321_RS00410	COG0494	nUDIX hydrolase
CNCMI4321_RS00430	COG0343	queuine tRNA-ribosyltransferase activity
CNCMI4321_RS00460	COG0697	spore germination
CNCMI4321_RS00465	COG0191	fructose-bisphosphate aldolase activity
CNCMI4321_RS00505	COG0477	Major facilitator Superfamily
CNCMI4321_RS00525	COG0366	Alpha amylase catalytic
CNCMI4321_RS00530	COG1609	Transcriptional regulator
CNCMI4321_RS00570	COG1175	transmembrane transport
CNCMI4321_RS00575	COG3833	ABC-type maltose transport systems, permease component
CNCMI4321_RS00590	COG1523	belongs to the glycosyl hydrolase 13 family
CNCMI4321_RS00610	COG0789	Transcriptional regulator
CNCMI4321_RS00625	COG1028	Short-chain dehydrogenase reductase Sdr
CNCMI4321_RS00630	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNCMI4321_RS00635	COG0586	Pfam SNARE associated Golgi protein
CNCMI4321_RS00680	COG1309	transcriptional regulator
CNCMI4321_RS00730	COG0527	aspartate kinase activity
CNCMI4321_RS00750	COG1940	carbohydrate kinase activity
CNCMI4321_RS00755	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
CNCMI4321_RS00765	COG0747	negative chemotaxis
CNCMI4321_RS00775	COG0444	Belongs to the ABC transporter superfamily
CNCMI4321_RS00780	COG4608	Belongs to the ABC transporter superfamily
CNCMI4321_RS00785	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNCMI4321_RS00810	COG2186	Transcriptional regulator
CNCMI4321_RS00845	COG1754	DNA topoisomerase type I activity
CNCMI4321_RS00845	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNCMI4321_RS00855	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
CNCMI4321_RS00870	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
CNCMI4321_RS00955	COG0672	)-iron permease
CNCMI4321_RS00960	COG3470	protein probably involved in high-affinity Fe2 transport
CNCMI4321_RS00970	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS00975	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS00980	COG1136	(ABC) transporter
CNCMI4321_RS01015	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
CNCMI4321_RS01020	COG0363	glucosamine-6-phosphate deaminase activity
CNCMI4321_RS01050	COG1216	Glycosyl transferase, family 2
CNCMI4321_RS01050	COG1442	glycosyl transferase family 8
CNCMI4321_RS01055	COG1309	transcriptional regulator
CNCMI4321_RS01075	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
CNCMI4321_RS01085	COG0305	Participates in initiation and elongation during chromosome replication
CNCMI4321_RS01090	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CNCMI4321_RS01095	COG3442	glutamine amidotransferase
CNCMI4321_RS01130	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
CNCMI4321_RS01180	COG1131	(ABC) transporter
CNCMI4321_RS01215	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CNCMI4321_RS01225	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CNCMI4321_RS01235	COG1937	Protein conserved in bacteria
CNCMI4321_RS01255	COG1131	(ABC) transporter
CNCMI4321_RS01330	COG2182	Extracellular solute-binding protein
CNCMI4321_RS01340	COG0395	ABC-type sugar transport system, permease component
CNCMI4321_RS01380	COG0745	RESPONSE REGULATOR receiver
CNCMI4321_RS01395	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
CNCMI4321_RS01410	COG4974	Belongs to the 'phage' integrase family
CNCMI4321_RS01805	COG0741	lytic transglycosylase activity
CNCMI4321_RS01805	COG1388	LysM domain
CNCMI4321_RS01825	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
CNCMI4321_RS01840	COG0356	it plays a direct role in the translocation of protons across the membrane
CNCMI4321_RS01875	COG0355	proton-transporting ATP synthase activity, rotational mechanism
CNCMI4321_RS01915	COG0251	oxidation-reduction process
CNCMI4321_RS01950	COG3842	ATPase activity
CNCMI4321_RS01965	COG1027	Aspartate ammonia-lyase
CNCMI4321_RS01975	COG0730	response to heat
CNCMI4321_RS01985	COG1609	Transcriptional regulator
CNCMI4321_RS01990	COG3119	arylsulfatase activity
CNCMI4321_RS02010	COG0395	ABC-type sugar transport system, permease component
CNCMI4321_RS02015	COG1373	ATPase (AAA superfamily
CNCMI4321_RS02035	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
CNCMI4321_RS02055	COG0569	domain protein
CNCMI4321_RS02055	COG0475	glutathione-regulated potassium exporter activity
CNCMI4321_RS02130	COG1704	LemA family
CNCMI4321_RS02165	COG1837	Belongs to the UPF0109 family
CNCMI4321_RS02200	COG0519	Catalyzes the synthesis of GMP from XMP
CNCMI4321_RS02205	COG0488	(ABC) transporter
CNCMI4321_RS02210	COG1487	ribonuclease activity
CNCMI4321_RS02220	COG0440	acetolactate synthase activity
CNCMI4321_RS02260	COG0667	Aldo Keto reductase
CNCMI4321_RS02310	COG1116	anion transmembrane transporter activity
CNCMI4321_RS02335	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
CNCMI4321_RS02340	COG1609	Transcriptional regulator
CNCMI4321_RS02355	COG2814	Major facilitator Superfamily
CNCMI4321_RS02355	COG0477	Major facilitator Superfamily
CNCMI4321_RS02365	COG4988	ABC transporter
CNCMI4321_RS02380	COG1653	transport
CNCMI4321_RS02400	COG3867	Arabinogalactan endo-beta-1,4-galactanase
CNCMI4321_RS02410	COG0656	L-ascorbic acid biosynthetic process
CNCMI4321_RS02430	COG2814	Major facilitator Superfamily
CNCMI4321_RS02445	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CNCMI4321_RS02455	COG2826	transposase and inactivated derivatives, IS30 family
CNCMI4321_RS02460	COG0438	transferase activity, transferring glycosyl groups
CNCMI4321_RS02465	COG0438	transferase activity, transferring glycosyl groups
CNCMI4321_RS02485	COG0463	Glycosyl transferase, family 2
CNCMI4321_RS02490	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
CNCMI4321_RS02595	COG0489	protein tyrosine kinase activity
CNCMI4321_RS02655	COG0095	Lipoate-protein ligase
CNCMI4321_RS02660	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNCMI4321_RS02665	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
CNCMI4321_RS02665	COG4499	WXG100 protein secretion system (Wss), protein YukC
CNCMI4321_RS02670	COG1902	pentaerythritol trinitrate reductase activity
CNCMI4321_RS02675	COG0167	dihydroorotate dehydrogenase activity
CNCMI4321_RS02680	COG1349	DNA-binding transcription factor activity
CNCMI4321_RS02690	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
CNCMI4321_RS02715	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
CNCMI4321_RS02750	COG0714	Associated with various cellular activities
CNCMI4321_RS02765	COG0210	DNA helicase
CNCMI4321_RS02785	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
CNCMI4321_RS02815	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
CNCMI4321_RS02820	COG2884	Cell division ATP-binding protein ftsE
CNCMI4321_RS02825	COG2177	Part of the ABC transporter FtsEX involved in
CNCMI4321_RS02830	COG3942	CHAP domain
CNCMI4321_RS02830	COG1388	LysM domain
CNCMI4321_RS02855	COG1126	abc transporter atp-binding protein
CNCMI4321_RS02865	COG0564	pseudouridine synthase activity
CNCMI4321_RS02870	COG1609	Transcriptional regulator
CNCMI4321_RS02880	COG1175	transmembrane transport
CNCMI4321_RS02885	COG0395	ABC-type sugar transport system, permease component
CNCMI4321_RS02895	COG1653	transport
CNCMI4321_RS02915	COG0601	transmembrane transport
CNCMI4321_RS02920	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNCMI4321_RS02930	COG4608	Belongs to the ABC transporter superfamily
CNCMI4321_RS02940	COG0626	cystathionine gamma-synthase activity
CNCMI4321_RS02945	COG0514	ATP-dependent DNA helicase (RecQ)
CNCMI4321_RS02960	COG0531	amino acid
CNCMI4321_RS02965	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
CNCMI4321_RS02975	COG0358	DNA primase activity
CNCMI4321_RS02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNCMI4321_RS02995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
CNCMI4321_RS03030	COG1609	Transcriptional regulator
CNCMI4321_RS03035	COG0366	Alpha amylase catalytic
CNCMI4321_RS03060	COG1136	(ABC) transporter
CNCMI4321_RS03060	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS03070	COG1136	(ABC) transporter
CNCMI4321_RS03070	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS03075	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
CNCMI4321_RS03080	COG0604	alcohol dehydrogenase
CNCMI4321_RS03085	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
CNCMI4321_RS03090	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
CNCMI4321_RS03110	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
CNCMI4321_RS03135	COG0701	Predicted permease
CNCMI4321_RS03155	COG0257	Belongs to the bacterial ribosomal protein bL36 family
CNCMI4321_RS03165	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
CNCMI4321_RS03170	COG0267	Belongs to the bacterial ribosomal protein bL33 family
CNCMI4321_RS03175	COG0227	Belongs to the bacterial ribosomal protein bL28 family
CNCMI4321_RS03200	COG1012	belongs to the aldehyde dehydrogenase family
CNCMI4321_RS03220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CNCMI4321_RS03255	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
CNCMI4321_RS03270	COG0436	Aminotransferase
CNCMI4321_RS03290	COG0385	Bile acid
CNCMI4321_RS03325	COG0583	DNA-binding transcription factor activity
CNCMI4321_RS03355	COG1063	alcohol dehydrogenase
CNCMI4321_RS03385	COG1175	transmembrane transport
CNCMI4321_RS03405	COG0583	DNA-binding transcription factor activity
CNCMI4321_RS03415	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
CNCMI4321_RS03440	COG0110	maltose O-acetyltransferase activity
CNCMI4321_RS03445	COG0110	maltose O-acetyltransferase activity
CNCMI4321_RS03470	COG2199	diguanylate cyclase activity
CNCMI4321_RS03475	COG0390	transport system, permease component
CNCMI4321_RS03480	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS03480	COG1136	(ABC) transporter
CNCMI4321_RS03505	COG0284	orotidine-5'-phosphate decarboxylase activity
CNCMI4321_RS03515	COG2176	DNA-directed DNA polymerase activity
CNCMI4321_RS03535	COG0626	cystathionine gamma-synthase activity
CNCMI4321_RS03585	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
CNCMI4321_RS03665	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
CNCMI4321_RS03680	COG1122	ATPase activity
CNCMI4321_RS03720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNCMI4321_RS03730	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNCMI4321_RS03735	COG4721	ABC-type cobalt transport system, permease component
CNCMI4321_RS03740	COG1122	ATPase activity
CNCMI4321_RS03750	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNCMI4321_RS03815	COG4115	mRNA cleavage
CNCMI4321_RS03845	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
CNCMI4321_RS03850	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
CNCMI4321_RS03905	COG0497	DNA recombination
CNCMI4321_RS03910	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNCMI4321_RS03960	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
CNCMI4321_RS03965	COG1472	Belongs to the glycosyl hydrolase 3 family
CNCMI4321_RS03980	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
CNCMI4321_RS03980	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
CNCMI4321_RS03995	COG0667	Aldo Keto reductase
CNCMI4321_RS04030	COG1760	l-serine dehydratase
CNCMI4321_RS04040	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
CNCMI4321_RS04065	COG1316	TRANSCRIPTIONal
CNCMI4321_RS04105	COG2205	protein histidine kinase activity
CNCMI4321_RS04110	COG0745	RESPONSE REGULATOR receiver
CNCMI4321_RS04135	COG1121	(ABC) transporter
CNCMI4321_RS04150	COG0539	negative regulation of cytoplasmic translation
CNCMI4321_RS04170	COG0469	pyruvate kinase activity
CNCMI4321_RS04175	COG0494	nUDIX hydrolase
CNCMI4321_RS04195	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
CNCMI4321_RS04200	COG1051	belongs to the nudix hydrolase family
CNCMI4321_RS04255	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
CNCMI4321_RS04260	COG0857	belongs to the CobB CobQ family
CNCMI4321_RS04260	COG0280	phosphate acetyltransferase
CNCMI4321_RS04300	COG0799	negative regulation of ribosome biogenesis
CNCMI4321_RS04305	COG0406	alpha-ribazole phosphatase activity
CNCMI4321_RS04320	COG0561	phosphatase activity
CNCMI4321_RS04335	COG2011	ABC-type metal ion transport system permease component
CNCMI4321_RS04340	COG1473	amidohydrolase
CNCMI4321_RS04355	COG1882	Formate acetyltransferase
CNCMI4321_RS04415	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
CNCMI4321_RS04420	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
CNCMI4321_RS04425	COG1611	Belongs to the LOG family
CNCMI4321_RS04440	COG1053	succinate dehydrogenase
CNCMI4321_RS04445	COG0758	DNA mediated transformation
CNCMI4321_RS04475	COG2873	o-acetylhomoserine
CNCMI4321_RS04480	COG1136	(ABC) transporter
CNCMI4321_RS04485	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS04485	COG1136	(ABC) transporter
CNCMI4321_RS04490	COG2197	response regulator
CNCMI4321_RS04505	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
CNCMI4321_RS04510	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNCMI4321_RS04515	COG1126	abc transporter atp-binding protein
CNCMI4321_RS04520	COG0765	amino acid transport
CNCMI4321_RS04525	COG0765	amino acid transport
CNCMI4321_RS04530	COG0012	GTP binding
CNCMI4321_RS04570	COG3177	Filamentation induced by cAMP protein fic
CNCMI4321_RS04620	COG1309	transcriptional regulator
CNCMI4321_RS04640	COG2814	Major facilitator Superfamily
CNCMI4321_RS04665	COG1940	carbohydrate kinase activity
CNCMI4321_RS04665	COG1846	Transcriptional regulator
CNCMI4321_RS04680	COG0477	Major facilitator Superfamily
CNCMI4321_RS04685	COG3119	arylsulfatase activity
CNCMI4321_RS04690	COG0641	radical SAM
CNCMI4321_RS04695	COG0730	response to heat
CNCMI4321_RS04735	COG2233	PERMEase
CNCMI4321_RS04740	COG0513	Belongs to the DEAD box helicase family
CNCMI4321_RS04750	COG0306	phosphate transporter
CNCMI4321_RS04760	COG2197	response regulator
CNCMI4321_RS04765	COG4585	Histidine kinase
CNCMI4321_RS04770	COG1131	(ABC) transporter
CNCMI4321_RS04800	COG3340	Belongs to the peptidase S51 family
CNCMI4321_RS04805	COG1335	isochorismatase
CNCMI4321_RS04855	COG1136	(ABC) transporter
CNCMI4321_RS04855	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS04865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
CNCMI4321_RS04945	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
CNCMI4321_RS04970	COG0719	Fe-S assembly protein
CNCMI4321_RS04975	COG0396	ATPase activity
CNCMI4321_RS04980	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
CNCMI4321_RS04990	COG2151	metal-sulfur cluster biosynthetic enzyme
CNCMI4321_RS05010	COG1385	rRNA (uridine-N3-)-methyltransferase activity
CNCMI4321_RS05015	COG0537	adenosine 5'-monophosphoramidase activity
CNCMI4321_RS05040	COG1022	Amp-dependent synthetase and ligase
CNCMI4321_RS05045	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
CNCMI4321_RS05070	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
CNCMI4321_RS05080	COG2860	membrane
CNCMI4321_RS05120	COG0069	glutamate synthase activity
CNCMI4321_RS05120	COG0067	glutamate synthase
CNCMI4321_RS05120	COG0070	glutamate synthase
CNCMI4321_RS05130	COG4166	transmembrane transport
CNCMI4321_RS05145	COG0297	glycogen (starch) synthase activity
CNCMI4321_RS05150	COG1119	ATPase activity
CNCMI4321_RS05160	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
CNCMI4321_RS05205	COG0456	acetyltransferase
CNCMI4321_RS05250	COG2946	Replication initiation factor
CNCMI4321_RS05310	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
CNCMI4321_RS05320	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
CNCMI4321_RS05340	COG0588	phosphoglycerate mutase activity
CNCMI4321_RS05350	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
CNCMI4321_RS05375	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
CNCMI4321_RS05380	COG0284	orotidine-5'-phosphate decarboxylase activity
CNCMI4321_RS05385	COG0543	2 iron, 2 sulfur cluster binding
CNCMI4321_RS05390	COG0167	dihydroorotate dehydrogenase activity
CNCMI4321_RS05410	COG0583	DNA-binding transcription factor activity
CNCMI4321_RS05425	COG0488	(ABC) transporter
CNCMI4321_RS05430	COG4221	oxidoreductase activity
CNCMI4321_RS05465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
CNCMI4321_RS05490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CNCMI4321_RS05505	COG0436	Aminotransferase
CNCMI4321_RS05520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
CNCMI4321_RS05620	COG0045	succinate-CoA ligase (ADP-forming) activity
CNCMI4321_RS05645	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
CNCMI4321_RS05650	COG1187	pseudouridine synthase activity
CNCMI4321_RS05715	COG1716	ATPase activity
CNCMI4321_RS05735	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
CNCMI4321_RS05750	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CNCMI4321_RS05765	COG0133	tryptophan synthase activity
CNCMI4321_RS05770	COG2135	peptidase activity
CNCMI4321_RS05780	COG0833	amino acid
CNCMI4321_RS05865	COG0833	amino acid
CNCMI4321_RS05875	COG3189	MarR family transcriptional regulator
CNCMI4321_RS05910	COG0693	protein deglycase activity
CNCMI4321_RS05920	COG0575	Belongs to the CDS family
CNCMI4321_RS05960	COG0516	GMP reductase activity
CNCMI4321_RS06030	COG3942	CHAP domain
CNCMI4321_RS06050	COG0551	DNA topoisomerase type I activity
CNCMI4321_RS06050	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNCMI4321_RS06190	COG1192	Involved in chromosome partitioning
CNCMI4321_RS06250	COG0456	acetyltransferase
CNCMI4321_RS06260	COG0802	atpase or kinase
CNCMI4321_RS06285	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNCMI4321_RS06290	COG0598	Magnesium transport protein CorA
CNCMI4321_RS06295	COG0406	alpha-ribazole phosphatase activity
CNCMI4321_RS06350	COG0395	ABC-type sugar transport system, permease component
CNCMI4321_RS06355	COG1175	transmembrane transport
CNCMI4321_RS06360	COG1653	transport
CNCMI4321_RS06400	COG4974	Belongs to the 'phage' integrase family
CNCMI4321_RS06435	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
CNCMI4321_RS06435	COG0551	DNA topoisomerase type I activity
CNCMI4321_RS06525	COG3942	CHAP domain
CNCMI4321_RS06525	COG1705	Flagellar rod assembly protein muramidase FlgJ
CNCMI4321_RS06615	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
CNCMI4321_RS06640	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
CNCMI4321_RS06655	COG1201	RNA secondary structure unwinding
CNCMI4321_RS06660	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNCMI4321_RS06670	COG0187	DNA topoisomerase II activity
CNCMI4321_RS06675	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
CNCMI4321_RS06685	COG0142	geranyltranstransferase activity
CNCMI4321_RS06705	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
CNCMI4321_RS06715	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
CNCMI4321_RS06740	COG1396	sequence-specific DNA binding
CNCMI4321_RS06745	COG1058	Belongs to the CinA family
CNCMI4321_RS06745	COG1546	Belongs to the CinA family
CNCMI4321_RS06775	COG2357	RelA SpoT domain protein
CNCMI4321_RS06805	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CNCMI4321_RS06830	COG0708	Exodeoxyribonuclease III
CNCMI4321_RS06840	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
CNCMI4321_RS06845	COG0601	transmembrane transport
CNCMI4321_RS06850	COG4166	transmembrane transport
CNCMI4321_RS06860	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS06860	COG1136	(ABC) transporter
CNCMI4321_RS06865	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS06875	COG0287	Prephenate dehydrogenase
CNCMI4321_RS06890	COG1217	gtp-binding protein TYPA
CNCMI4321_RS06900	COG4591	ABC-type transport system involved in lipoprotein release permease component
CNCMI4321_RS06900	COG1136	(ABC) transporter
CNCMI4321_RS06910	COG0477	Major facilitator Superfamily
CNCMI4321_RS06925	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
CNCMI4321_RS06930	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
CNCMI4321_RS06940	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
CNCMI4321_RS06945	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
CNCMI4321_RS06960	COG1929	Belongs to the glycerate kinase type-1 family
CNCMI4321_RS06975	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
CNCMI4321_RS06995	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
CNCMI4321_RS07005	COG2017	converts alpha-aldose to the beta-anomer
CNCMI4321_RS07010	COG2017	converts alpha-aldose to the beta-anomer
CNCMI4321_RS07020	COG1595	DNA-templated transcription, initiation
CNCMI4321_RS07040	COG1196	nuclear chromosome segregation
CNCMI4321_RS07045	COG0285	dihydrofolate synthase activity
CNCMI4321_RS07050	COG0006	proline dipeptidase activity
CNCMI4321_RS07070	COG1940	carbohydrate kinase activity
CNCMI4321_RS07075	COG1940	carbohydrate kinase activity
CNCMI4321_RS07095	COG0738	Major facilitator superfamily
CNCMI4321_RS07105	COG4974	Belongs to the 'phage' integrase family
CNCMI4321_RS07330	COG3723	Recombinational DNA repair protein, rece pathway
CNCMI4321_RS07335	COG5377	YqaJ viral recombinase family
CNCMI4321_RS07450	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
CNCMI4321_RS07460	COG0768	penicillin binding
CNCMI4321_RS07485	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNCMI4321_RS07515	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
CNCMI4321_RS07525	COG1643	Atp-dependent helicase
CNCMI4321_RS07530	COG2814	Major facilitator Superfamily
CNCMI4321_RS07580	COG0656	L-ascorbic acid biosynthetic process
CNCMI4321_RS07590	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNCMI4321_RS07630	COG4716	Myosin-crossreactive antigen
CNCMI4321_RS07645	COG0587	DNA-directed DNA polymerase activity
CNCMI4321_RS07685	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
CNCMI4321_RS07710	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNCMI4321_RS07715	COG0351	phosphomethylpyrimidine kinase
CNCMI4321_RS07715	COG0352	thiamine-phosphate diphosphorylase activity
CNCMI4321_RS07730	COG2271	Major facilitator Superfamily
CNCMI4321_RS07740	COG2197	response regulator
CNCMI4321_RS07810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNCMI4321_RS07815	COG2814	Major facilitator Superfamily
CNCMI4321_RS07820	COG0745	RESPONSE REGULATOR receiver
CNCMI4321_RS07830	COG4581	dead DEAH box helicase
CNCMI4321_RS07835	COG2326	polyphosphate kinase activity
CNCMI4321_RS07840	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
CNCMI4321_RS07845	COG1279	arginine transmembrane transporter activity
CNCMI4321_RS07855	COG0765	amino acid transport
CNCMI4321_RS07860	COG0765	amino acid transport
CNCMI4321_RS07865	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
CNCMI4321_RS07870	COG1126	abc transporter atp-binding protein
CNCMI4321_RS07890	COG1196	nuclear chromosome segregation
CNCMI4321_RS07905	COG0477	Major facilitator Superfamily
CNCMI4321_RS07920	COG0589	response to stress
CNCMI4321_RS07930	COG1278	Cold shock
CNCMI4321_RS07935	COG2205	protein histidine kinase activity
CNCMI4321_RS07940	COG0745	RESPONSE REGULATOR receiver
CNCMI4321_RS07960	COG1278	Cold shock
CNCMI4321_RS07975	COG0714	Associated with various cellular activities
CNCMI4321_RS08020	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
CNCMI4321_RS08050	COG4122	O-methyltransferase activity
CNCMI4321_RS08055	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
CNCMI4321_RS08060	COG1011	Hydrolase
CNCMI4321_RS08070	COG0586	Pfam SNARE associated Golgi protein
CNCMI4321_RS08075	COG0560	Phosphoserine phosphatase
CNCMI4321_RS08080	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
CNCMI4321_RS08115	COG4974	Belongs to the 'phage' integrase family
CNCMI4321_RS08130	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
CNCMI4321_RS08135	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
CNCMI4321_RS08150	COG3842	ATPase activity
CNCMI4321_RS08160	COG1176	ABC-type spermidine putrescine transport system, permease component I
CNCMI4321_RS08165	COG1840	ABC-type Fe3 transport system, periplasmic component
CNCMI4321_RS08180	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
CNCMI4321_RS08185	COG3069	C4-dicarboxylate transmembrane transporter activity
CNCMI4321_RS08205	COG1132	(ABC) transporter
CNCMI4321_RS08210	COG1132	(ABC) transporter
CNCMI4321_RS08220	COG1472	Belongs to the glycosyl hydrolase 3 family
CNCMI4321_RS08260	COG1309	transcriptional regulator
CNCMI4321_RS08275	COG0602	queuosine metabolic process
CNCMI4321_RS08280	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
CNCMI4321_RS08280	COG1328	CTP reductase activity
CNCMI4321_RS08285	COG1570	exodeoxyribonuclease VII activity
CNCMI4321_RS08290	COG1722	exodeoxyribonuclease VII activity
CNCMI4321_RS08295	COG2249	NAD(P)H dehydrogenase (quinone) activity
CNCMI4321_RS08300	COG1022	Amp-dependent synthetase and ligase
CNCMI4321_RS08305	COG1970	mechanosensitive ion channel activity
CNCMI4321_RS08325	COG0248	Ppx GppA phosphatase
CNCMI4321_RS08330	COG0436	Aminotransferase
CNCMI4321_RS08395	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
CNCMI4321_RS08410	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
CNCMI4321_RS08415	COG0009	L-threonylcarbamoyladenylate synthase
CNCMI4321_RS08465	COG2814	Major facilitator Superfamily
CNCMI4321_RS08475	COG0242	peptide deformylase activity
CNCMI4321_RS08495	COG1940	carbohydrate kinase activity
CNCMI4321_RS08520	COG1946	Acyl-CoA thioesterase
CNCMI4321_RS08530	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
CNCMI4321_RS08545	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
CNCMI4321_RS08550	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
CNCMI4321_RS08575	COG1215	transferase activity, transferring glycosyl groups
CNCMI4321_RS08585	COG0463	Glycosyl transferase, family 2
CNCMI4321_RS08590	COG1454	alcohol dehydrogenase
CNCMI4321_RS08595	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
CNCMI4321_RS08710	COG3942	CHAP domain
CNCMI4321_RS08710	COG1705	Flagellar rod assembly protein muramidase FlgJ
CNCMI4321_RS08790	COG3843	relaxase mobilization nuclease domain protein
CNCMI4321_RS08810	COG1475	DNA binding
CNCMI4321_RS08820	COG4585	Histidine kinase
CNCMI4321_RS08825	COG2197	response regulator
CNCMI4321_RS08850	COG1132	(ABC) transporter
CNCMI4321_RS08855	COG1136	(ABC) transporter
CNCMI4321_RS08855	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS08865	COG4585	Histidine kinase
CNCMI4321_RS08890	COG4974	Belongs to the 'phage' integrase family
CNCMI4321_RS08945	COG0488	(ABC) transporter
CNCMI4321_RS09025	COG3942	CHAP domain
CNCMI4321_RS09025	COG1705	Flagellar rod assembly protein muramidase FlgJ
CNCMI4321_RS09035	COG0758	DNA mediated transformation
CNCMI4321_RS09050	COG1126	abc transporter atp-binding protein
CNCMI4321_RS09085	COG3843	relaxase mobilization nuclease domain protein
CNCMI4321_RS09105	COG1475	DNA binding
CNCMI4321_RS09140	COG3250	beta-galactosidase activity
CNCMI4321_RS09150	COG1609	Transcriptional regulator
CNCMI4321_RS09180	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS09200	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
CNCMI4321_RS09220	COG0589	response to stress
CNCMI4321_RS09225	COG1388	LysM domain
CNCMI4321_RS09225	COG3103	Sh3 type 3 domain protein
CNCMI4321_RS09225	COG0791	NLP P60 protein
CNCMI4321_RS09235	COG3942	CHAP domain
CNCMI4321_RS09235	COG1705	Flagellar rod assembly protein muramidase FlgJ
CNCMI4321_RS09250	COG5002	protein histidine kinase activity
CNCMI4321_RS09265	COG1575	Belongs to the MenA family. Type 1 subfamily
CNCMI4321_RS09270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
CNCMI4321_RS09285	COG2814	Major facilitator Superfamily
CNCMI4321_RS09320	COG2197	response regulator
CNCMI4321_RS09340	COG0395	ABC-type sugar transport system, permease component
CNCMI4321_RS09345	COG1175	transmembrane transport
CNCMI4321_RS09365	COG1803	Methylglyoxal synthase
CNCMI4321_RS09365	COG1597	lipid kinase activity
CNCMI4321_RS09395	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
CNCMI4321_RS09400	COG0328	RNA-DNA hybrid ribonuclease activity
CNCMI4321_RS09425	COG0196	riboflavin kinase activity
CNCMI4321_RS09470	COG2308	Evidence 4 Homologs of previously reported genes of
CNCMI4321_RS09575	COG0255	Belongs to the universal ribosomal protein uL29 family
CNCMI4321_RS09625	COG3527	Alpha-acetolactate decarboxylase
CNCMI4321_RS09635	COG1012	belongs to the aldehyde dehydrogenase family
CNCMI4321_RS09635	COG1454	alcohol dehydrogenase
CNCMI4321_RS09645	COG1063	alcohol dehydrogenase
CNCMI4321_RS09700	COG1739	Uncharacterized protein family UPF0029
CNCMI4321_RS09705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
CNCMI4321_RS09715	COG2723	6-phospho-beta-galactosidase activity
CNCMI4321_RS09725	COG1175	transmembrane transport
CNCMI4321_RS09735	COG1609	Transcriptional regulator
CNCMI4321_RS09750	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
CNCMI4321_RS09765	COG0531	amino acid
CNCMI4321_RS09770	COG0812	UDP-N-acetylmuramate dehydrogenase activity
CNCMI4321_RS09815	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
CNCMI4321_RS09865	COG2252	PERMEase
CNCMI4321_RS09890	COG0745	RESPONSE REGULATOR receiver
CNCMI4321_RS09895	COG5002	protein histidine kinase activity
CNCMI4321_RS09900	COG0477	Major facilitator Superfamily
CNCMI4321_RS09910	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CNCMI4321_RS09915	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
CNCMI4321_RS09925	COG3250	beta-galactosidase activity
CNCMI4321_RS09930	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
CNCMI4321_RS09945	COG0395	ABC-type sugar transport system, permease component
CNCMI4321_RS09950	COG1175	transmembrane transport
CNCMI4321_RS09955	COG1653	transport
CNCMI4321_RS09970	COG3579	cysteine-type endopeptidase activity
CNCMI4321_RS09985	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
CNCMI4321_RS10000	COG0826	peptidase U32
CNCMI4321_RS10010	COG0742	ribosomal rna small subunit methyltransferase
CNCMI4321_RS10025	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
CNCMI4321_RS10025	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
CNCMI4321_RS10030	COG2270	Major facilitator Superfamily
CNCMI4321_RS10035	COG0789	Transcriptional regulator
CNCMI4321_RS10140	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
CNCMI4321_RS10145	COG4770	biotin carboxylase activity
CNCMI4321_RS10150	COG1268	BioY protein
CNCMI4321_RS10190	COG0250	Participates in transcription elongation, termination and antitermination
CNCMI4321_RS10195	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
CNCMI4321_RS10205	COG0436	Aminotransferase
CNCMI4321_RS10235	COG1530	ribonuclease E activity
CNCMI4321_RS10240	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
CNCMI4321_RS10250	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
CNCMI4321_RS10275	COG4948	Mandelate Racemase Muconate Lactonizing
CNCMI4321_RS10280	COG1609	Transcriptional regulator
CNCMI4321_RS10310	COG0083	homoserine kinase activity
CNCMI4321_RS10315	COG0460	homoserine dehydrogenase
CNCMI4321_RS10320	COG1263	PTS System
CNCMI4321_RS10320	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNCMI4321_RS10320	COG2190	(PTS) system
CNCMI4321_RS10325	COG1263	PTS System
CNCMI4321_RS10325	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNCMI4321_RS10325	COG2190	(PTS) system
CNCMI4321_RS10340	COG1309	transcriptional regulator
CNCMI4321_RS10350	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
CNCMI4321_RS10355	COG0446	pyridine nucleotide-disulphide oxidoreductase
CNCMI4321_RS10365	COG0765	amino acid transport
CNCMI4321_RS10380	COG1126	abc transporter atp-binding protein
CNCMI4321_RS10385	COG0167	dihydroorotate dehydrogenase activity
CNCMI4321_RS10430	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
CNCMI4321_RS10435	COG0406	alpha-ribazole phosphatase activity
CNCMI4321_RS10435	COG0494	nUDIX hydrolase
CNCMI4321_RS10470	COG0584	glycerophosphoryl diester phosphodiesterase
CNCMI4321_RS10495	COG0179	Fumarylacetoacetate (FAA) hydrolase
CNCMI4321_RS10515	COG3311	Transcriptional regulator
CNCMI4321_RS10540	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNCMI4321_RS10545	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNCMI4321_RS10550	COG1129	ABC transporter
CNCMI4321_RS10560	COG1070	Carbohydrate kinase
CNCMI4321_RS10575	COG1216	Glycosyl transferase, family 2
CNCMI4321_RS10575	COG1442	glycosyl transferase family 8
CNCMI4321_RS10585	COG1368	sulfuric ester hydrolase activity
CNCMI4321_RS10590	COG1216	Glycosyl transferase, family 2
CNCMI4321_RS10590	COG0438	transferase activity, transferring glycosyl groups
CNCMI4321_RS10615	COG1088	dTDP-glucose 4,6-dehydratase activity
CNCMI4321_RS10635	COG1376	ErfK ybiS ycfS ynhG family protein
CNCMI4321_RS10645	COG1316	TRANSCRIPTIONal
CNCMI4321_RS10650	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS10655	COG1129	ABC transporter
CNCMI4321_RS10680	COG0084	hydrolase, TatD family'
CNCMI4321_RS10685	COG1132	(ABC) transporter
CNCMI4321_RS10690	COG1132	(ABC) transporter
CNCMI4321_RS10710	COG0395	ABC-type sugar transport system, permease component
CNCMI4321_RS10715	COG1175	transmembrane transport
CNCMI4321_RS10725	COG1609	Transcriptional regulator
CNCMI4321_RS10730	COG1874	Beta-galactosidase
CNCMI4321_RS10760	COG4166	transmembrane transport
CNCMI4321_RS10845	COG1846	Transcriptional regulator
CNCMI4321_RS10855	COG1113	amino acid transport
CNCMI4321_RS10865	COG0577	efflux transmembrane transporter activity
CNCMI4321_RS10865	COG1136	(ABC) transporter
CNCMI4321_RS10870	COG1113	amino acid transport
CNCMI4321_RS10890	COG1609	Transcriptional regulator
CNCMI4321_RS10900	COG0588	phosphoglycerate mutase activity
CNCMI4321_RS10950	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
CNCMI4321_RS10955	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
CNCMI4321_RS10960	COG0366	Alpha amylase catalytic
CNCMI4321_RS10965	COG0395	ABC-type sugar transport system, permease component
CNCMI4321_RS10970	COG1175	transmembrane transport
CNCMI4321_RS10995	COG0590	tRNA wobble adenosine to inosine editing
CNCMI4321_RS10995	COG0037	tRNA processing
CNCMI4321_RS11000	COG0025	NhaP-type Na H and K H
CNCMI4321_RS11005	COG0730	response to heat
CNCMI4321_RS11030	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
CNCMI4321_RS11040	COG2190	(PTS) system
CNCMI4321_RS11040	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNCMI4321_RS11040	COG1263	PTS System
CNCMI4321_RS11045	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
CNCMI4321_RS11045	COG1263	PTS System
CNCMI4321_RS11055	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
CNCMI4321_RS11090	COG1609	Transcriptional regulator
CNCMI4321_RS11095	COG1879	ABC-type sugar transport system periplasmic component
CNCMI4321_RS11105	COG1172	Belongs to the binding-protein-dependent transport system permease family
CNCMI4321_RS11115	COG3415	Transposase
CNCMI4321_RS11115	COG2801	Transposase and inactivated derivatives
CNCMI4321_RS11125	COG3842	ATPase activity
CNCMI4321_RS11130	COG2188	Transcriptional regulator
CNCMI4321_RS11145	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
CNCMI4321_RS11150	COG1215	transferase activity, transferring glycosyl groups
CNCMI4321_RS11160	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
CNCMI4321_RS11200	COG3583	domain protein
CNCMI4321_RS11220	COG0617	tRNA 3'-terminal CCA addition
CNCMI4321_RS11240	COG0492	ferredoxin-NADP+ reductase activity
CNCMI4321_RS11250	COG1192	Involved in chromosome partitioning
CNCMI4321_RS11260	COG1847	R3H domain protein