locus-tag	class	description
DRBB28_RS00015	COG0592	DNA-directed DNA polymerase activity
DRBB28_RS00030	COG0187	DNA topoisomerase II activity
DRBB28_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DRBB28_RS00045	COG1609	Transcriptional regulator
DRBB28_RS00055	COG3250	beta-galactosidase activity
DRBB28_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
DRBB28_RS00145	COG0783	Belongs to the Dps family
DRBB28_RS00165	COG1609	Transcriptional regulator
DRBB28_RS00185	COG1609	Transcriptional regulator
DRBB28_RS00230	COG1609	Transcriptional regulator
DRBB28_RS00240	COG0783	Belongs to the Dps family
DRBB28_RS00245	COG1253	flavin adenine dinucleotide binding
DRBB28_RS00310	COG2203	Gaf domain
DRBB28_RS00310	COG3706	GGDEF domain
DRBB28_RS00310	COG4251	negative regulation of phosphorylation
DRBB28_RS00310	COG5001	Diguanylate cyclase
DRBB28_RS00330	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
DRBB28_RS00340	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
DRBB28_RS00355	COG0180	Tryptophanyl-tRNA synthetase
DRBB28_RS00370	COG0058	SHG alpha-glucan phosphorylase activity
DRBB28_RS00410	COG0515	serine threonine protein kinase
DRBB28_RS00415	COG0768	penicillin binding
DRBB28_RS00450	COG0071	Belongs to the small heat shock protein (HSP20) family
DRBB28_RS00455	COG0697	spore germination
DRBB28_RS00465	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
DRBB28_RS00470	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
DRBB28_RS00505	COG0494	nUDIX hydrolase
DRBB28_RS00525	COG0343	queuine tRNA-ribosyltransferase activity
DRBB28_RS00555	COG0697	spore germination
DRBB28_RS00560	COG0191	fructose-bisphosphate aldolase activity
DRBB28_RS00595	COG1609	Transcriptional regulator
DRBB28_RS00600	COG0477	Major facilitator Superfamily
DRBB28_RS00630	COG0366	Alpha amylase catalytic
DRBB28_RS00635	COG1609	Transcriptional regulator
DRBB28_RS00675	COG1175	transmembrane transport
DRBB28_RS00680	COG3833	ABC-type maltose transport systems, permease component
DRBB28_RS00690	COG1609	Transcriptional regulator
DRBB28_RS00695	COG1523	belongs to the glycosyl hydrolase 13 family
DRBB28_RS00715	COG0789	Transcriptional regulator
DRBB28_RS00735	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
DRBB28_RS00740	COG0586	Pfam SNARE associated Golgi protein
DRBB28_RS00785	COG1309	transcriptional regulator
DRBB28_RS00830	COG0527	aspartate kinase activity
DRBB28_RS00850	COG1940	carbohydrate kinase activity
DRBB28_RS00855	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
DRBB28_RS00865	COG0747	negative chemotaxis
DRBB28_RS00875	COG0444	Belongs to the ABC transporter superfamily
DRBB28_RS00880	COG4608	Belongs to the ABC transporter superfamily
DRBB28_RS00885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DRBB28_RS00910	COG2186	Transcriptional regulator
DRBB28_RS00945	COG1754	DNA topoisomerase type I activity
DRBB28_RS00945	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DRBB28_RS00955	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
DRBB28_RS00970	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
DRBB28_RS01055	COG3619	membrane
DRBB28_RS01060	COG1733	regulation of RNA biosynthetic process
DRBB28_RS01065	COG2910	NAD(P)H-binding
DRBB28_RS01080	COG0477	Major facilitator Superfamily
DRBB28_RS01085	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
DRBB28_RS01090	COG3321	synthase
DRBB28_RS01090	COG1028	Short-chain dehydrogenase reductase Sdr
DRBB28_RS01090	COG0604	alcohol dehydrogenase
DRBB28_RS01100	COG2977	Belongs to the P-Pant transferase superfamily
DRBB28_RS01165	COG0672	)-iron permease
DRBB28_RS01170	COG3470	protein probably involved in high-affinity Fe2 transport
DRBB28_RS01180	COG0577	efflux transmembrane transporter activity
DRBB28_RS01185	COG0577	efflux transmembrane transporter activity
DRBB28_RS01190	COG1136	(ABC) transporter
DRBB28_RS01225	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
DRBB28_RS01230	COG0363	glucosamine-6-phosphate deaminase activity
DRBB28_RS01260	COG1216	Glycosyl transferase, family 2
DRBB28_RS01260	COG1442	glycosyl transferase family 8
DRBB28_RS01265	COG1309	transcriptional regulator
DRBB28_RS01285	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
DRBB28_RS01295	COG0305	Participates in initiation and elongation during chromosome replication
DRBB28_RS01300	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DRBB28_RS01305	COG3442	glutamine amidotransferase
DRBB28_RS01330	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
DRBB28_RS01365	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DRBB28_RS01375	COG1937	Protein conserved in bacteria
DRBB28_RS01395	COG1131	(ABC) transporter
DRBB28_RS01470	COG2182	Extracellular solute-binding protein
DRBB28_RS01480	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS01520	COG0745	RESPONSE REGULATOR receiver
DRBB28_RS01535	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
DRBB28_RS01550	COG4974	Belongs to the 'phage' integrase family
DRBB28_RS01945	COG1388	LysM domain
DRBB28_RS01945	COG0741	lytic transglycosylase activity
DRBB28_RS01965	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
DRBB28_RS01980	COG0356	it plays a direct role in the translocation of protons across the membrane
DRBB28_RS02015	COG0355	proton-transporting ATP synthase activity, rotational mechanism
DRBB28_RS02055	COG0251	oxidation-reduction process
DRBB28_RS02090	COG3842	ATPase activity
DRBB28_RS02105	COG1027	Aspartate ammonia-lyase
DRBB28_RS02115	COG0730	response to heat
DRBB28_RS02120	COG0641	radical SAM
DRBB28_RS02125	COG1609	Transcriptional regulator
DRBB28_RS02130	COG3119	arylsulfatase activity
DRBB28_RS02150	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS02155	COG1373	ATPase (AAA superfamily
DRBB28_RS02175	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
DRBB28_RS02195	COG0475	glutathione-regulated potassium exporter activity
DRBB28_RS02195	COG0569	domain protein
DRBB28_RS02295	COG1475	DNA binding
DRBB28_RS02360	COG4695	Portal protein
DRBB28_RS02465	COG0741	lytic transglycosylase activity
DRBB28_RS02465	COG1388	LysM domain
DRBB28_RS02530	COG1136	(ABC) transporter
DRBB28_RS02540	COG1704	LemA family
DRBB28_RS02565	COG1957	nucleoside hydrolase
DRBB28_RS02575	COG1653	transport
DRBB28_RS02580	COG1175	transmembrane transport
DRBB28_RS02585	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS02610	COG1837	Belongs to the UPF0109 family
DRBB28_RS02645	COG0505	Belongs to the CarA family
DRBB28_RS02650	COG0488	(ABC) transporter
DRBB28_RS02655	COG1487	ribonuclease activity
DRBB28_RS02665	COG0440	acetolactate synthase activity
DRBB28_RS02705	COG0667	Aldo Keto reductase
DRBB28_RS02755	COG1116	anion transmembrane transporter activity
DRBB28_RS02780	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
DRBB28_RS02785	COG1609	Transcriptional regulator
DRBB28_RS02800	COG2814	Major facilitator Superfamily
DRBB28_RS02800	COG0477	Major facilitator Superfamily
DRBB28_RS02810	COG4988	ABC transporter
DRBB28_RS02825	COG1653	transport
DRBB28_RS02830	COG1175	transmembrane transport
DRBB28_RS02835	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS02850	COG3867	Arabinogalactan endo-beta-1,4-galactanase
DRBB28_RS02860	COG0656	L-ascorbic acid biosynthetic process
DRBB28_RS02880	COG2814	Major facilitator Superfamily
DRBB28_RS02895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DRBB28_RS02905	COG0438	transferase activity, transferring glycosyl groups
DRBB28_RS02920	COG1216	Glycosyl transferase, family 2
DRBB28_RS02920	COG1442	glycosyl transferase family 8
DRBB28_RS02925	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
DRBB28_RS02935	COG1216	Glycosyl transferase, family 2
DRBB28_RS02965	COG1484	DNA-dependent DNA replication
DRBB28_RS03055	COG0489	protein tyrosine kinase activity
DRBB28_RS03120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DRBB28_RS03125	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
DRBB28_RS03125	COG4499	WXG100 protein secretion system (Wss), protein YukC
DRBB28_RS03130	COG1902	pentaerythritol trinitrate reductase activity
DRBB28_RS03135	COG0167	dihydroorotate dehydrogenase activity
DRBB28_RS03140	COG1349	DNA-binding transcription factor activity
DRBB28_RS03150	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
DRBB28_RS03175	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
DRBB28_RS03210	COG0714	Associated with various cellular activities
DRBB28_RS03225	COG0210	DNA helicase
DRBB28_RS03245	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
DRBB28_RS03275	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
DRBB28_RS03280	COG2884	Cell division ATP-binding protein ftsE
DRBB28_RS03285	COG2177	Part of the ABC transporter FtsEX involved in
DRBB28_RS03290	COG1388	LysM domain
DRBB28_RS03290	COG3942	CHAP domain
DRBB28_RS03315	COG1126	abc transporter atp-binding protein
DRBB28_RS03325	COG0564	pseudouridine synthase activity
DRBB28_RS03330	COG1609	Transcriptional regulator
DRBB28_RS03340	COG1175	transmembrane transport
DRBB28_RS03345	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS03355	COG1653	transport
DRBB28_RS03370	COG4166	transmembrane transport
DRBB28_RS03375	COG0601	transmembrane transport
DRBB28_RS03380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
DRBB28_RS03390	COG4608	Belongs to the ABC transporter superfamily
DRBB28_RS03400	COG0626	cystathionine gamma-synthase activity
DRBB28_RS03405	COG0514	ATP-dependent DNA helicase (RecQ)
DRBB28_RS03420	COG0531	amino acid
DRBB28_RS03425	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
DRBB28_RS03435	COG0358	DNA primase activity
DRBB28_RS03450	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
DRBB28_RS03455	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
DRBB28_RS03490	COG1609	Transcriptional regulator
DRBB28_RS03495	COG0366	Alpha amylase catalytic
DRBB28_RS03520	COG0577	efflux transmembrane transporter activity
DRBB28_RS03520	COG1136	(ABC) transporter
DRBB28_RS03530	COG1136	(ABC) transporter
DRBB28_RS03530	COG0577	efflux transmembrane transporter activity
DRBB28_RS03540	COG0604	alcohol dehydrogenase
DRBB28_RS03545	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
DRBB28_RS03550	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
DRBB28_RS03570	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
DRBB28_RS03595	COG0701	Predicted permease
DRBB28_RS03625	COG1012	belongs to the aldehyde dehydrogenase family
DRBB28_RS03645	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DRBB28_RS03680	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
DRBB28_RS03695	COG0436	Aminotransferase
DRBB28_RS03715	COG0385	Bile acid
DRBB28_RS03750	COG0583	DNA-binding transcription factor activity
DRBB28_RS03780	COG1063	alcohol dehydrogenase
DRBB28_RS03810	COG1175	transmembrane transport
DRBB28_RS03830	COG0583	DNA-binding transcription factor activity
DRBB28_RS03840	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DRBB28_RS03865	COG0110	maltose O-acetyltransferase activity
DRBB28_RS03870	COG0110	maltose O-acetyltransferase activity
DRBB28_RS03900	COG0390	transport system, permease component
DRBB28_RS03905	COG0577	efflux transmembrane transporter activity
DRBB28_RS03905	COG1136	(ABC) transporter
DRBB28_RS03930	COG0284	orotidine-5'-phosphate decarboxylase activity
DRBB28_RS03940	COG2176	DNA-directed DNA polymerase activity
DRBB28_RS03960	COG0626	cystathionine gamma-synthase activity
DRBB28_RS04010	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
DRBB28_RS04090	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
DRBB28_RS04105	COG1122	ATPase activity
DRBB28_RS04140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DRBB28_RS04150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DRBB28_RS04155	COG4721	ABC-type cobalt transport system, permease component
DRBB28_RS04160	COG1122	ATPase activity
DRBB28_RS04170	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DRBB28_RS04230	COG4115	mRNA cleavage
DRBB28_RS04260	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
DRBB28_RS04265	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
DRBB28_RS04380	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
DRBB28_RS04410	COG0667	Aldo Keto reductase
DRBB28_RS04445	COG1760	l-serine dehydratase
DRBB28_RS04455	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
DRBB28_RS04480	COG1316	TRANSCRIPTIONal
DRBB28_RS04520	COG2205	protein histidine kinase activity
DRBB28_RS04525	COG0745	RESPONSE REGULATOR receiver
DRBB28_RS04545	COG1108	ABC-type Mn2 Zn2 transport systems permease components
DRBB28_RS04550	COG1121	(ABC) transporter
DRBB28_RS04565	COG0539	negative regulation of cytoplasmic translation
DRBB28_RS04585	COG0469	pyruvate kinase activity
DRBB28_RS04590	COG0494	nUDIX hydrolase
DRBB28_RS04610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
DRBB28_RS04615	COG1051	belongs to the nudix hydrolase family
DRBB28_RS04670	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
DRBB28_RS04675	COG0280	phosphate acetyltransferase
DRBB28_RS04675	COG0857	belongs to the CobB CobQ family
DRBB28_RS04715	COG0799	negative regulation of ribosome biogenesis
DRBB28_RS04720	COG0406	alpha-ribazole phosphatase activity
DRBB28_RS04750	COG2011	ABC-type metal ion transport system permease component
DRBB28_RS04755	COG1473	amidohydrolase
DRBB28_RS04770	COG1882	Formate acetyltransferase
DRBB28_RS04830	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
DRBB28_RS04835	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
DRBB28_RS04840	COG1611	Belongs to the LOG family
DRBB28_RS04855	COG1053	succinate dehydrogenase
DRBB28_RS04860	COG0758	DNA mediated transformation
DRBB28_RS04890	COG2873	o-acetylhomoserine
DRBB28_RS04895	COG1136	(ABC) transporter
DRBB28_RS04900	COG0577	efflux transmembrane transporter activity
DRBB28_RS04900	COG1136	(ABC) transporter
DRBB28_RS04905	COG2197	response regulator
DRBB28_RS04920	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
DRBB28_RS04925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DRBB28_RS04930	COG1126	abc transporter atp-binding protein
DRBB28_RS04935	COG0765	amino acid transport
DRBB28_RS04940	COG0765	amino acid transport
DRBB28_RS04945	COG0012	GTP binding
DRBB28_RS04970	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
DRBB28_RS04985	COG3177	Filamentation induced by cAMP protein fic
DRBB28_RS05035	COG1309	transcriptional regulator
DRBB28_RS05050	COG2814	Major facilitator Superfamily
DRBB28_RS05075	COG1940	carbohydrate kinase activity
DRBB28_RS05075	COG1846	Transcriptional regulator
DRBB28_RS05090	COG0477	Major facilitator Superfamily
DRBB28_RS05095	COG3119	arylsulfatase activity
DRBB28_RS05100	COG0641	radical SAM
DRBB28_RS05105	COG0730	response to heat
DRBB28_RS05145	COG2233	PERMEase
DRBB28_RS05150	COG0513	Belongs to the DEAD box helicase family
DRBB28_RS05160	COG0306	phosphate transporter
DRBB28_RS05170	COG2197	response regulator
DRBB28_RS05175	COG4585	Histidine kinase
DRBB28_RS05180	COG1131	(ABC) transporter
DRBB28_RS05210	COG3340	Belongs to the peptidase S51 family
DRBB28_RS05215	COG1335	isochorismatase
DRBB28_RS05230	COG3655	Transcriptional regulator
DRBB28_RS05265	COG1136	(ABC) transporter
DRBB28_RS05265	COG0577	efflux transmembrane transporter activity
DRBB28_RS05275	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
DRBB28_RS05355	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
DRBB28_RS05380	COG0719	Fe-S assembly protein
DRBB28_RS05385	COG0396	ATPase activity
DRBB28_RS05390	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
DRBB28_RS05400	COG2151	metal-sulfur cluster biosynthetic enzyme
DRBB28_RS05420	COG1385	rRNA (uridine-N3-)-methyltransferase activity
DRBB28_RS05425	COG0537	adenosine 5'-monophosphoramidase activity
DRBB28_RS05450	COG1022	Amp-dependent synthetase and ligase
DRBB28_RS05455	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
DRBB28_RS05480	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
DRBB28_RS05490	COG2860	membrane
DRBB28_RS05530	COG0070	glutamate synthase
DRBB28_RS05530	COG0067	glutamate synthase
DRBB28_RS05530	COG0069	glutamate synthase activity
DRBB28_RS05540	COG4166	transmembrane transport
DRBB28_RS05555	COG0297	glycogen (starch) synthase activity
DRBB28_RS05560	COG1119	ATPase activity
DRBB28_RS05565	COG0561	phosphatase activity
DRBB28_RS05565	COG0561	phosphatase activity
DRBB28_RS05570	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
DRBB28_RS05645	COG1073	alpha beta
DRBB28_RS05650	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
DRBB28_RS05660	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
DRBB28_RS05680	COG0588	phosphoglycerate mutase activity
DRBB28_RS05690	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
DRBB28_RS05715	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
DRBB28_RS05720	COG0284	orotidine-5'-phosphate decarboxylase activity
DRBB28_RS05730	COG0167	dihydroorotate dehydrogenase activity
DRBB28_RS05750	COG0583	DNA-binding transcription factor activity
DRBB28_RS05765	COG0488	(ABC) transporter
DRBB28_RS05770	COG4221	oxidoreductase activity
DRBB28_RS05805	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
DRBB28_RS05830	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DRBB28_RS05845	COG0436	Aminotransferase
DRBB28_RS05860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
DRBB28_RS06055	COG1475	DNA binding
DRBB28_RS06135	COG4974	Belongs to the 'phage' integrase family
DRBB28_RS06220	COG0045	succinate-CoA ligase (ADP-forming) activity
DRBB28_RS06245	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
DRBB28_RS06250	COG1187	pseudouridine synthase activity
DRBB28_RS06315	COG1716	ATPase activity
DRBB28_RS06335	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
DRBB28_RS06350	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DRBB28_RS06365	COG0133	tryptophan synthase activity
DRBB28_RS06370	COG2135	peptidase activity
DRBB28_RS06380	COG0833	amino acid
DRBB28_RS06460	COG0745	RESPONSE REGULATOR receiver
DRBB28_RS06475	COG4181	ATPase activity
DRBB28_RS06500	COG0833	amino acid
DRBB28_RS06510	COG3189	MarR family transcriptional regulator
DRBB28_RS06545	COG0693	protein deglycase activity
DRBB28_RS06555	COG0575	Belongs to the CDS family
DRBB28_RS06595	COG0516	GMP reductase activity
DRBB28_RS06665	COG3942	CHAP domain
DRBB28_RS06685	COG0551	DNA topoisomerase type I activity
DRBB28_RS06685	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
DRBB28_RS06830	COG1192	Involved in chromosome partitioning
DRBB28_RS06890	COG0456	acetyltransferase
DRBB28_RS06900	COG0802	atpase or kinase
DRBB28_RS06925	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DRBB28_RS06930	COG0598	Magnesium transport protein CorA
DRBB28_RS06935	COG0406	alpha-ribazole phosphatase activity
DRBB28_RS06985	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS06990	COG1175	transmembrane transport
DRBB28_RS06995	COG1653	transport
DRBB28_RS07035	COG0477	Major facilitator Superfamily
DRBB28_RS07050	COG2977	Belongs to the P-Pant transferase superfamily
DRBB28_RS07120	COG0456	acetyltransferase
DRBB28_RS07155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
DRBB28_RS07180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
DRBB28_RS07195	COG2207	Transcriptional regulator
DRBB28_RS07205	COG1201	RNA secondary structure unwinding
DRBB28_RS07210	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DRBB28_RS07220	COG0187	DNA topoisomerase II activity
DRBB28_RS07225	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
DRBB28_RS07235	COG0142	geranyltranstransferase activity
DRBB28_RS07255	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
DRBB28_RS07265	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
DRBB28_RS07290	COG1396	sequence-specific DNA binding
DRBB28_RS07295	COG1058	Belongs to the CinA family
DRBB28_RS07295	COG1546	Belongs to the CinA family
DRBB28_RS07325	COG2357	RelA SpoT domain protein
DRBB28_RS07350	COG2197	response regulator
DRBB28_RS07365	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DRBB28_RS07390	COG0708	Exodeoxyribonuclease III
DRBB28_RS07405	COG0601	transmembrane transport
DRBB28_RS07410	COG4166	transmembrane transport
DRBB28_RS07420	COG1136	(ABC) transporter
DRBB28_RS07420	COG0577	efflux transmembrane transporter activity
DRBB28_RS07425	COG0577	efflux transmembrane transporter activity
DRBB28_RS07435	COG0287	Prephenate dehydrogenase
DRBB28_RS07450	COG1217	gtp-binding protein TYPA
DRBB28_RS07460	COG4591	ABC-type transport system involved in lipoprotein release permease component
DRBB28_RS07460	COG1136	(ABC) transporter
DRBB28_RS07470	COG0477	Major facilitator Superfamily
DRBB28_RS07485	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
DRBB28_RS07490	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
DRBB28_RS07500	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
DRBB28_RS07505	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
DRBB28_RS07520	COG1929	Belongs to the glycerate kinase type-1 family
DRBB28_RS07535	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
DRBB28_RS07555	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
DRBB28_RS07565	COG2017	converts alpha-aldose to the beta-anomer
DRBB28_RS07570	COG2017	converts alpha-aldose to the beta-anomer
DRBB28_RS07580	COG1595	DNA-templated transcription, initiation
DRBB28_RS07600	COG1196	nuclear chromosome segregation
DRBB28_RS07605	COG0285	dihydrofolate synthase activity
DRBB28_RS07610	COG0006	proline dipeptidase activity
DRBB28_RS07630	COG1940	carbohydrate kinase activity
DRBB28_RS07635	COG1940	carbohydrate kinase activity
DRBB28_RS07655	COG0738	Major facilitator superfamily
DRBB28_RS07700	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
DRBB28_RS07710	COG0768	penicillin binding
DRBB28_RS07735	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DRBB28_RS07765	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
DRBB28_RS07775	COG1643	Atp-dependent helicase
DRBB28_RS07780	COG2814	Major facilitator Superfamily
DRBB28_RS07830	COG0656	L-ascorbic acid biosynthetic process
DRBB28_RS07840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DRBB28_RS07880	COG4716	Myosin-crossreactive antigen
DRBB28_RS07895	COG0587	DNA-directed DNA polymerase activity
DRBB28_RS07935	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
DRBB28_RS07960	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DRBB28_RS07965	COG0351	phosphomethylpyrimidine kinase
DRBB28_RS07965	COG0352	thiamine-phosphate diphosphorylase activity
DRBB28_RS07980	COG2271	Major facilitator Superfamily
DRBB28_RS07990	COG2197	response regulator
DRBB28_RS08060	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DRBB28_RS08065	COG2814	Major facilitator Superfamily
DRBB28_RS08070	COG0745	RESPONSE REGULATOR receiver
DRBB28_RS08085	COG2326	polyphosphate kinase activity
DRBB28_RS08095	COG1279	arginine transmembrane transporter activity
DRBB28_RS08105	COG0765	amino acid transport
DRBB28_RS08110	COG0765	amino acid transport
DRBB28_RS08115	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
DRBB28_RS08120	COG1126	abc transporter atp-binding protein
DRBB28_RS08140	COG1196	nuclear chromosome segregation
DRBB28_RS08155	COG0477	Major facilitator Superfamily
DRBB28_RS08170	COG0589	response to stress
DRBB28_RS08180	COG1278	Cold shock
DRBB28_RS08185	COG2205	protein histidine kinase activity
DRBB28_RS08190	COG0745	RESPONSE REGULATOR receiver
DRBB28_RS08210	COG1278	Cold shock
DRBB28_RS08225	COG0714	Associated with various cellular activities
DRBB28_RS08270	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
DRBB28_RS08300	COG4122	O-methyltransferase activity
DRBB28_RS08305	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
DRBB28_RS08315	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DRBB28_RS08320	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DRBB28_RS08320	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
DRBB28_RS08320	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DRBB28_RS08335	COG1011	Hydrolase
DRBB28_RS08345	COG0586	Pfam SNARE associated Golgi protein
DRBB28_RS08350	COG0560	Phosphoserine phosphatase
DRBB28_RS08390	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
DRBB28_RS08455	COG1116	anion transmembrane transporter activity
DRBB28_RS08455	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
DRBB28_RS08470	COG1228	amidohydrolase
DRBB28_RS08475	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
DRBB28_RS08480	COG1122	ATPase activity
DRBB28_RS08490	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
DRBB28_RS08525	COG1132	(ABC) transporter
DRBB28_RS08530	COG1132	(ABC) transporter
DRBB28_RS08605	COG1309	transcriptional regulator
DRBB28_RS08620	COG0602	queuosine metabolic process
DRBB28_RS08625	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
DRBB28_RS08625	COG1328	CTP reductase activity
DRBB28_RS08630	COG1570	exodeoxyribonuclease VII activity
DRBB28_RS08635	COG1722	exodeoxyribonuclease VII activity
DRBB28_RS08640	COG2249	NAD(P)H dehydrogenase (quinone) activity
DRBB28_RS08645	COG1022	Amp-dependent synthetase and ligase
DRBB28_RS08650	COG1970	mechanosensitive ion channel activity
DRBB28_RS08670	COG0248	Ppx GppA phosphatase
DRBB28_RS08675	COG0436	Aminotransferase
DRBB28_RS08745	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
DRBB28_RS08760	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
DRBB28_RS08765	COG0009	L-threonylcarbamoyladenylate synthase
DRBB28_RS08820	COG2814	Major facilitator Superfamily
DRBB28_RS08830	COG0242	peptide deformylase activity
DRBB28_RS08850	COG1940	carbohydrate kinase activity
DRBB28_RS08875	COG1946	Acyl-CoA thioesterase
DRBB28_RS08885	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
DRBB28_RS08900	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
DRBB28_RS08905	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
DRBB28_RS08930	COG1215	transferase activity, transferring glycosyl groups
DRBB28_RS08940	COG0463	Glycosyl transferase, family 2
DRBB28_RS08945	COG1454	alcohol dehydrogenase
DRBB28_RS08950	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
DRBB28_RS08995	COG0488	(ABC) transporter
DRBB28_RS09020	COG1569	PIN domain
DRBB28_RS09045	COG1705	Flagellar rod assembly protein muramidase FlgJ
DRBB28_RS09045	COG3942	CHAP domain
DRBB28_RS09115	COG1475	DNA binding
DRBB28_RS09150	COG3250	beta-galactosidase activity
DRBB28_RS09160	COG1609	Transcriptional regulator
DRBB28_RS09195	COG0577	efflux transmembrane transporter activity
DRBB28_RS09215	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
DRBB28_RS09235	COG0589	response to stress
DRBB28_RS09240	COG0791	NLP P60 protein
DRBB28_RS09240	COG1388	LysM domain
DRBB28_RS09240	COG3103	Sh3 type 3 domain protein
DRBB28_RS09250	COG3942	CHAP domain
DRBB28_RS09250	COG1705	Flagellar rod assembly protein muramidase FlgJ
DRBB28_RS09255	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
DRBB28_RS09265	COG5002	protein histidine kinase activity
DRBB28_RS09280	COG1575	Belongs to the MenA family. Type 1 subfamily
DRBB28_RS09285	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
DRBB28_RS09295	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS09300	COG2814	Major facilitator Superfamily
DRBB28_RS09335	COG2197	response regulator
DRBB28_RS09355	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS09360	COG1175	transmembrane transport
DRBB28_RS09380	COG1597	lipid kinase activity
DRBB28_RS09380	COG1803	Methylglyoxal synthase
DRBB28_RS09410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
DRBB28_RS09415	COG0328	RNA-DNA hybrid ribonuclease activity
DRBB28_RS09440	COG0196	riboflavin kinase activity
DRBB28_RS09485	COG2308	Evidence 4 Homologs of previously reported genes of
DRBB28_RS09590	COG0255	Belongs to the universal ribosomal protein uL29 family
DRBB28_RS09640	COG3527	Alpha-acetolactate decarboxylase
DRBB28_RS09650	COG1012	belongs to the aldehyde dehydrogenase family
DRBB28_RS09650	COG1454	alcohol dehydrogenase
DRBB28_RS09660	COG1063	alcohol dehydrogenase
DRBB28_RS09715	COG1739	Uncharacterized protein family UPF0029
DRBB28_RS09720	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
DRBB28_RS09730	COG2723	6-phospho-beta-galactosidase activity
DRBB28_RS09740	COG1175	transmembrane transport
DRBB28_RS09750	COG1609	Transcriptional regulator
DRBB28_RS09765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
DRBB28_RS09780	COG0531	amino acid
DRBB28_RS09785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
DRBB28_RS09830	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
DRBB28_RS09880	COG2252	PERMEase
DRBB28_RS09905	COG0745	RESPONSE REGULATOR receiver
DRBB28_RS09910	COG5002	protein histidine kinase activity
DRBB28_RS09915	COG0477	Major facilitator Superfamily
DRBB28_RS09925	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DRBB28_RS09930	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
DRBB28_RS09945	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
DRBB28_RS09960	COG0826	peptidase U32
DRBB28_RS09970	COG0742	ribosomal rna small subunit methyltransferase
DRBB28_RS09985	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
DRBB28_RS09985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
DRBB28_RS09990	COG2270	Major facilitator Superfamily
DRBB28_RS09995	COG0789	Transcriptional regulator
DRBB28_RS10095	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
DRBB28_RS10100	COG4770	biotin carboxylase activity
DRBB28_RS10105	COG1268	BioY protein
DRBB28_RS10145	COG0250	Participates in transcription elongation, termination and antitermination
DRBB28_RS10150	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
DRBB28_RS10160	COG0436	Aminotransferase
DRBB28_RS10190	COG1530	ribonuclease E activity
DRBB28_RS10195	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
DRBB28_RS10205	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
DRBB28_RS10230	COG4948	Mandelate Racemase Muconate Lactonizing
DRBB28_RS10235	COG1609	Transcriptional regulator
DRBB28_RS10265	COG0083	homoserine kinase activity
DRBB28_RS10270	COG0460	homoserine dehydrogenase
DRBB28_RS10275	COG1263	PTS System
DRBB28_RS10275	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRBB28_RS10275	COG2190	(PTS) system
DRBB28_RS10280	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRBB28_RS10280	COG1263	PTS System
DRBB28_RS10280	COG2190	(PTS) system
DRBB28_RS10295	COG1309	transcriptional regulator
DRBB28_RS10305	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
DRBB28_RS10310	COG0446	pyridine nucleotide-disulphide oxidoreductase
DRBB28_RS10320	COG0765	amino acid transport
DRBB28_RS10335	COG1126	abc transporter atp-binding protein
DRBB28_RS10385	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
DRBB28_RS10390	COG0494	nUDIX hydrolase
DRBB28_RS10390	COG0406	alpha-ribazole phosphatase activity
DRBB28_RS10425	COG0584	glycerophosphoryl diester phosphodiesterase
DRBB28_RS10450	COG0179	Fumarylacetoacetate (FAA) hydrolase
DRBB28_RS10475	COG1172	Belongs to the binding-protein-dependent transport system permease family
DRBB28_RS10480	COG1172	Belongs to the binding-protein-dependent transport system permease family
DRBB28_RS10485	COG1129	ABC transporter
DRBB28_RS10495	COG1070	Carbohydrate kinase
DRBB28_RS10510	COG1216	Glycosyl transferase, family 2
DRBB28_RS10510	COG1442	glycosyl transferase family 8
DRBB28_RS10520	COG1368	sulfuric ester hydrolase activity
DRBB28_RS10525	COG1368	sulfuric ester hydrolase activity
DRBB28_RS10550	COG1216	Glycosyl transferase, family 2
DRBB28_RS10565	COG1088	dTDP-glucose 4,6-dehydratase activity
DRBB28_RS10590	COG1316	TRANSCRIPTIONal
DRBB28_RS10595	COG0577	efflux transmembrane transporter activity
DRBB28_RS10600	COG1129	ABC transporter
DRBB28_RS10625	COG0084	hydrolase, TatD family'
DRBB28_RS10630	COG1132	(ABC) transporter
DRBB28_RS10635	COG1132	(ABC) transporter
DRBB28_RS10660	COG4166	transmembrane transport
DRBB28_RS10680	COG3579	cysteine-type endopeptidase activity
DRBB28_RS10740	COG1846	Transcriptional regulator
DRBB28_RS10750	COG1113	amino acid transport
DRBB28_RS10760	COG1136	(ABC) transporter
DRBB28_RS10760	COG0577	efflux transmembrane transporter activity
DRBB28_RS10765	COG1113	amino acid transport
DRBB28_RS10785	COG1609	Transcriptional regulator
DRBB28_RS10790	COG2182	Extracellular solute-binding protein
DRBB28_RS10795	COG0588	phosphoglycerate mutase activity
DRBB28_RS10870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
DRBB28_RS10875	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
DRBB28_RS10880	COG0366	Alpha amylase catalytic
DRBB28_RS10885	COG0395	ABC-type sugar transport system, permease component
DRBB28_RS10890	COG1175	transmembrane transport
DRBB28_RS10915	COG0037	tRNA processing
DRBB28_RS10915	COG0590	tRNA wobble adenosine to inosine editing
DRBB28_RS10920	COG0025	NhaP-type Na H and K H
DRBB28_RS10925	COG0730	response to heat
DRBB28_RS10950	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
DRBB28_RS10960	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRBB28_RS10960	COG1263	PTS System
DRBB28_RS10960	COG2190	(PTS) system
DRBB28_RS10965	COG1263	PTS System
DRBB28_RS10965	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
DRBB28_RS10975	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
DRBB28_RS11010	COG1609	Transcriptional regulator
DRBB28_RS11015	COG1879	ABC-type sugar transport system periplasmic component
DRBB28_RS11025	COG1172	Belongs to the binding-protein-dependent transport system permease family
DRBB28_RS11035	COG3415	Transposase
DRBB28_RS11035	COG2801	Transposase and inactivated derivatives
DRBB28_RS11045	COG3842	ATPase activity
DRBB28_RS11065	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
DRBB28_RS11070	COG1215	transferase activity, transferring glycosyl groups
DRBB28_RS11080	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
DRBB28_RS11115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
DRBB28_RS11120	COG1472	Belongs to the glycosyl hydrolase 3 family
DRBB28_RS11140	COG3583	domain protein
DRBB28_RS11160	COG0617	tRNA 3'-terminal CCA addition
DRBB28_RS11180	COG0492	ferredoxin-NADP+ reductase activity
DRBB28_RS11185	COG1475	DNA binding
DRBB28_RS11190	COG1192	Involved in chromosome partitioning
DRBB28_RS11200	COG1847	R3H domain protein