locus-tag	class	description
D3H49_RS00015	ENOG4105XH8	RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme (By similarity)
D3H49_RS00020	ENOG4105VAS	Could be involved in insertion of integral membrane proteins into the membrane (By similarity)
D3H49_RS00025	ENOG4105DHW	Required for the insertion and or proper folding and or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins
D3H49_RS00040	ENOG4107QJE	Chromosome Partitioning Protein
D3H49_RS00050	ENOG4105C3M	thioredoxin reductase
D3H49_RS00070	ENOG4105D4J	Catalyzes the addition and repair of the essential 3'- terminal CCA sequence in tRNAs without using a nucleic acid template. Adds these three nucleotides in the order of C, C, and A to the tRNA nucleotide-73, using CTP and ATP as substrates and producing inorganic pyrophosphate
D3H49_RS00085	ENOG4105D1X	Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits (By similarity)
D3H49_RS00090	ENOG4106839	domain protein
D3H49_RS00115	ENOG4105DY9	regulatoR
D3H49_RS00130	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D3H49_RS00155	ENOG4105BZH	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides (By similarity)
D3H49_RS00170	ENOG4108XBJ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane (By similarity)
D3H49_RS00180	ENOG4105CZC	PTS system ascorbate-specific transporter subunit IIC
D3H49_RS00185	ENOG4105FDP	GntR family transcriptional regulator
D3H49_RS00225	ENOG4105CNN	ABC, transporter
D3H49_RS00235	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
D3H49_RS00240	ENOG4105FKQ	transcriptional regulator
D3H49_RS00270	ENOG4105DSB	aldose 1-epimerase
D3H49_RS00275	ENOG4105C2N	RNA methyltransferase TrmH family group 3
D3H49_RS00290	ENOG4105CI1	PTS System
D3H49_RS00300	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
D3H49_RS00325	ENOG4105HF0	Membrane
D3H49_RS00330	ENOG4107SUZ	Sodium/hydrogen exchanger family
D3H49_RS00335	ENOG4108FWV	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D3H49_RS00365	ENOG4105CG3	alpha amylase, catalytic region
D3H49_RS00370	ENOG4105C7B	Threonine dehydratase
D3H49_RS00375	ENOG4105NDF	NAD-dependent protein deacetylase which modulates the activities of several enzymes which are inactive in their acetylated form. May also have NAD-dependent lysine demalonylase and desuccinylase activity (By similarity)
D3H49_RS00435	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D3H49_RS00445	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS00465	ENOG4105C85	amino acid
D3H49_RS00470	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D3H49_RS00480	ENOG4105C85	amino acid
D3H49_RS00495	ENOG4105BZ1	(ABC) transporter
D3H49_RS00570	ENOG4105BZ1	(ABC) transporter
D3H49_RS00575	ENOG4105BZ1	(ABC) transporter
D3H49_RS00580	ENOG4105F8V	Hydrolase, tatD family
D3H49_RS00585	ENOG4105DFH	Transport of potassium into the cell (By similarity)
D3H49_RS00600	ENOG4105C2J	ABC transporter
D3H49_RS00605	ENOG4107WD8	ABC transporter, permease
D3H49_RS00610	ENOG4108KGH	TRANSCRIPTIONal
D3H49_RS00620	ENOG4105S7A	ErfK ybiS ycfS ynhG family protein
D3H49_RS00640	ENOG4105C1B	dTDP-glucose 4-6-dehydratase
D3H49_RS00650	ENOG4108I19	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis (By similarity)
D3H49_RS00660	ENOG4105EY8	ABC transporter
D3H49_RS00670	ENOG4107T7U	Sulfatase
D3H49_RS00705	ENOG4105C2J	ABC transporter
D3H49_RS00710	ENOG4105CNN	ABC, transporter
D3H49_RS00715	ENOG4105CNN	ABC, transporter
D3H49_RS00740	ENOG4105ERH	Fumarylacetoacetate hydrolase
D3H49_RS00750	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D3H49_RS00755	ENOG4106F3G	Catalyzes the tRNA-independent activation of glutamate in presence of ATP and the subsequent transfer of glutamate onto a tRNA(Asp). Glutamate is transferred on the 2-amino-5-(4,5- dihydroxy-2-cyclopenten-1-yl) moiety of the queuosine in the wobble position of the QUC anticodon (By similarity)
D3H49_RS00760	ENOG4108QXE	glycerophosphoryl diester phosphodiesterase
D3H49_RS00805	ENOG4105CUU	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP) (By similarity)
D3H49_RS00840	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D3H49_RS00855	ENOG4105E5Q	amino acid AbC transporter
D3H49_RS00870	ENOG4107QMW	pyridine nucleotide-disulfide oxidoreductase
D3H49_RS00875	ENOG4105CDF	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (By similarity)
D3H49_RS00900	ENOG4105CI1	PTS System
D3H49_RS00905	ENOG4108IIZ	The phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS), a major carbohydrate active -transport system, catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane
D3H49_RS00910	ENOG4105D6E	homoserine dehydrogenase
D3H49_RS00915	ENOG4105D5I	Catalyzes the ATP-dependent phosphorylation of L- homoserine to L-homoserine phosphate (By similarity)
D3H49_RS00920	ENOG4108JW7	Maf-like protein
D3H49_RS00945	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS00950	ENOG4105DIA	mandelate racemase muconate lactonizing
D3H49_RS00955	ENOG4107EXU	Short-chain dehydrogenase reductase Sdr
D3H49_RS00970	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D3H49_RS00980	ENOG4107R4C	succinyl-diaminopimelate desuccinylase
D3H49_RS00985	ENOG4105C03	ribonuclease
D3H49_RS01000	ENOG4105C9R	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate (By similarity). It may play a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
D3H49_RS01030	ENOG4105E5V	Participates in transcription elongation, termination and antitermination (By similarity)
D3H49_RS01060	ENOG4107ZYJ	bioY protein
D3H49_RS01065	ENOG4108JIK	carboxylase
D3H49_RS01070	ENOG4105D8K	carboxyl transferase
D3H49_RS01150	ENOG4105DEU	major facilitator superfamily
D3H49_RS01155	ENOG4105DW0	Catalyzes the ADP transfer to D-glycero-D-manno-heptose 1-phosphate, yielding ADP-D,D-heptose (By similarity)
D3H49_RS01170	ENOG4106H78	methyltransferase
D3H49_RS01180	ENOG4105CFP	Peptidase U32
D3H49_RS01185	ENOG4105DBW	Multi-copper polyphenol oxidoreductase laccase
D3H49_RS01210	ENOG4105CTZ	aminopeptidase c
D3H49_RS01215	ENOG41082NP	Multiple antibiotic resistance
D3H49_RS01220	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS01225	ENOG4108IJG	ABC transporter substrate-binding protein
D3H49_RS01230	ENOG4105DB9	Binding-protein-dependent transport systems inner membrane component
D3H49_RS01235	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
D3H49_RS01250	ENOG4107URF	beta-phospho-glucomutase
D3H49_RS01265	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D3H49_RS01270	ENOG4105E99	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP) (By similarity)
D3H49_RS01275	ENOG4105DUF	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively (By similarity)
D3H49_RS01280	ENOG4105CSH	Transporter
D3H49_RS01285	ENOG4105BZU	Histidine kinase
D3H49_RS01290	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D3H49_RS01310	ENOG4105BZY	Part of the ABC transporter complex PstSACB involved in phosphate import. Responsible for energy coupling to the transport system (By similarity)
D3H49_RS01315	ENOG4105C7N	Xanthine uracil vitamin C permease
D3H49_RS01360	ENOG41080UU	5-formyltetrahydrofolate cyclo-ligase
D3H49_RS01400	ENOG4107R4N	Cell wall formation (By similarity)
D3H49_RS01405	ENOG4105CUB	amino acid
D3H49_RS01410	ENOG4108Z4U	Ferredoxin
D3H49_RS01420	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D3H49_RS01435	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS01470	ENOG4108ZK7	protein family UPF0029, Impact, N-terminal protein
D3H49_RS01505	ENOG4105IE8	Alpha-ketoglutarate permease
D3H49_RS01520	ENOG4105IE8	Alpha-ketoglutarate permease
D3H49_RS01525	ENOG4105CPQ	Dehydrogenase
D3H49_RS01535	ENOG4108EKI	Dehydrogenase
D3H49_RS01545	ENOG4107FQX	Alpha-acetolactate decarboxylase
D3H49_RS01595	ENOG41082SA	50s ribosomal protein l29
D3H49_RS01625	ENOG4108UJY	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit (By similarity)
D3H49_RS01650	ENOG4108UZ0	Binds to the 23S rRNA (By similarity)
D3H49_RS01655	ENOG4105CGG	The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently (By similarity)
D3H49_RS01660	ENOG4105CC8	Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism (By similarity)
D3H49_RS01665	ENOG4105K9U	however, it seems to stimulate more or less all the activities of the other two initiation factors, IF-2 and IF-3 (By similarity)
D3H49_RS01670	ENOG41067V7	50S ribosomal protein L36
D3H49_RS01675	ENOG4108Z04	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
D3H49_RS01715	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS01765	ENOG4105E66	phosphoriboisomerase A
D3H49_RS01770	ENOG4108UMW	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D3H49_RS01775	ENOG4107QN2	dihydrolipoyl dehydrogenase
D3H49_RS01810	ENOG4105CGR	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity)
D3H49_RS01830	ENOG4105F66	Binding-protein-dependent transport systems inner membrane component
D3H49_RS01850	ENOG4105WH1	Two component transcriptional regulator luxr family
D3H49_RS01885	ENOG4105F27	Major Facilitator
D3H49_RS01890	ENOG4105I1K	ABC transporter
D3H49_RS01900	ENOG4105CRK	lysyL-tRNA synthetase
D3H49_RS01905	ENOG4105EIS	1,4-dihydroxy-2-naphthoate octaprenyltransferase
D3H49_RS01915	ENOG4108UTW	Plays a role in the regulation of phosphate uptake
D3H49_RS01930	ENOG4107R8H	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine (By similarity)
D3H49_RS01935	ENOG4108S4A	n-acetylmuramoyl-l-alanine amidase
D3H49_RS01950	ENOG4108YV4	Universal stress protein
D3H49_RS01960	ENOG4105C0V	Provides the sole de novo source of dTMP for DNA biosynthesis (By similarity)
D3H49_RS01970	ENOG4105KJF	protein tyrosine phosphatase
D3H49_RS01980	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D3H49_RS01990	ENOG4107WD8	ABC transporter, permease
D3H49_RS02030	ENOG4105CQ4	Transcriptional regulator
D3H49_RS02040	ENOG4105CNT	hydrolase family 2
D3H49_RS02045	ENOG4107RBJ	symporter
D3H49_RS02060	ENOG4105CZ1	Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA (By similarity)
D3H49_RS02075	ENOG4105CV9	cyclopropane-fatty-acyl-phospholipid synthase
D3H49_RS02080	ENOG4105C0A	alcohol dehydrogenase
D3H49_RS02085	ENOG4105CKK	Glycosyl transferase, family 2
D3H49_RS02115	ENOG4107RD1	Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine (By similarity)
D3H49_RS02120	ENOG4108UGV	hypoxanthine phosphoribosyltransferase
D3H49_RS02125	ENOG4105C3H	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins (By similarity)
D3H49_RS02170	ENOG4105DKQ	ROK family
D3H49_RS02190	ENOG4107YDN	peptide deformylase
D3H49_RS02215	ENOG4105C8K	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA (By similarity)
D3H49_RS02220	ENOG4105EQY	Methylates the class 1 translation termination release factors RF1 PrfA and RF2 PrfB on the glutamine residue of the universally conserved GGQ motif (By similarity)
D3H49_RS02245	ENOG4105C32	Amino acid ABC transporter (Permease)
D3H49_RS02250	ENOG4105CF8	branched-chain amino acid ABC transporter, permease
D3H49_RS02255	ENOG4105C0Z	ABC transporter
D3H49_RS02260	ENOG4108IV0	ABC, transporter
D3H49_RS02265	ENOG4107UIY	sua5 ycio yrdc ywlc family protein
D3H49_RS02270	ENOG4105ESV	Glycosyl transferase, family 4
D3H49_RS02275	ENOG4105CP4	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth (By similarity)
D3H49_RS02280	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
D3H49_RS02285	ENOG4107QUV	Domain protein
D3H49_RS02300	ENOG4105C90	Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction proline is first activated by ATP to form Pro- AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys- tRNA(Pro) is not edited by ProRS (By similarity)
D3H49_RS02310	ENOG4105C9K	Endothelin-converting enzyme 1
D3H49_RS02330	ENOG4105EJ3	Catalyzes the conversion of the cyclic tetrahydrodipicolinate (THDP) into the acyclic N-succinyl-L-2- amino-6-oxopimelate using succinyl-CoA (By similarity)
D3H49_RS02355	ENOG4105CHM	Aminotransferase
D3H49_RS02360	ENOG4107R33	ppx gppa phosphatase
D3H49_RS02380	ENOG4105M2E	Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell (By similarity)
D3H49_RS02385	ENOG4108IQE	Amp-dependent synthetase and ligase
D3H49_RS02390	ENOG4108K2R	Glutathione-regulated potassium-efflux system ancillary protein
D3H49_RS02395	ENOG4105YX8	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D3H49_RS02400	ENOG4105DVS	Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides (By similarity)
D3H49_RS02405	ENOG4105CJD	(Anaerobic) ribonucleoside-triphosphate reductase
D3H49_RS02410	ENOG4108RDD	Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine (By similarity)
D3H49_RS02425	ENOG41067SE	Tetr family transcriptional regulator
D3H49_RS02430	ENOG4107QK4	glycoside hydrolase, family 3 domain protein
D3H49_RS02460	ENOG4107FKK	extracellular solute-binding protein family 1
D3H49_RS02470	ENOG4105C3P	Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln) (By similarity)
D3H49_RS02480	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS02555	ENOG4108US0	Transcription regulator that can specifically activate or repress expression of target genes (By similarity)
D3H49_RS02560	ENOG4105BZ1	(ABC) transporter
D3H49_RS02565	ENOG4105BZ1	(ABC) transporter
D3H49_RS02590	ENOG4108JJB	ABC transporter
D3H49_RS02595	ENOG4108ZGB	N-(5'-phosphoribosyl)anthranilate isomerase
D3H49_RS02600	ENOG4105D7K	pfkb domain protein
D3H49_RS02610	ENOG4108VXP	Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stress (By similarity)
D3H49_RS02615	ENOG4107QW4	alcohol dehydrogenase
D3H49_RS02620	ENOG4108RVA	ribokinase
D3H49_RS02640	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS02645	ENOG4105C2J	ABC transporter
D3H49_RS02650	ENOG4105CNN	ABC, transporter
D3H49_RS02655	ENOG4105E9V	Periplasmic binding protein LacI transcriptional regulator
D3H49_RS02660	ENOG4105MRB	Catalyzes the interconversion of beta-pyran and beta- furan forms of D-ribose (By similarity)
D3H49_RS02665	ENOG4108RVA	ribokinase
D3H49_RS02670	ENOG4105C07	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile) (By similarity)
D3H49_RS02675	ENOG4107RUE	extracellular solute-binding protein family 1
D3H49_RS02680	ENOG4105F38	ABC transporter, permease
D3H49_RS02690	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D3H49_RS02705	ENOG4105DZR	Type I site-specific deoxyribonuclease
D3H49_RS02710	ENOG4105CVR	type I restriction-modification system
D3H49_RS02760	ENOG4105DZR	Type I site-specific deoxyribonuclease
D3H49_RS02770	ENOG4107R3N	Filamentation induced by cAMP protein fic
D3H49_RS02785	ENOG4105C01	Dihydroxy-acid dehydratase
D3H49_RS02800	ENOG4107RSZ	Primosomal protein n'
D3H49_RS02805	ENOG4105EAC	phosphoserine phosphatase
D3H49_RS02810	ENOG4107T5V	SNARE associated Golgi
D3H49_RS02815	ENOG4105DHM	ATPase which is responsible for recognizing, binding, unfolding and translocation of pupylated proteins into the bacterial 20S proteasome core particle. May be essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase may function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis (By similarity)
D3H49_RS02820	ENOG4105EJU	HAD-superfamily hydrolase subfamily IA variant 3
D3H49_RS02835	ENOG4105DM4	PTS System
D3H49_RS02840	ENOG4108YRF	PTS System
D3H49_RS02850	ENOG4105UP7	3-epimerase
D3H49_RS02855	ENOG4105E5F	proteasome
D3H49_RS02860	ENOG4105ECY	inositol monophosphatase
D3H49_RS02875	ENOG4108426	dNA-binding protein
D3H49_RS02885	ENOG4107QTF	adenylosuccinate lyase
D3H49_RS02930	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D3H49_RS02935	ENOG4105D5S	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine (By similarity)
D3H49_RS02945	ENOG4105VEQ	Cold shock protein
D3H49_RS02965	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D3H49_RS02970	ENOG4105BZU	Histidine kinase
D3H49_RS02975	ENOG4105VEQ	Cold shock protein
D3H49_RS02985	ENOG4108YV4	Universal stress protein
D3H49_RS02990	ENOG4105C2Z	ATP-dependent CLP protease ATP-binding subunit
D3H49_RS03015	ENOG4105C99	atpase involved in dna repair
D3H49_RS03035	ENOG4105CDA	abc transporter atp-binding protein
D3H49_RS03040	ENOG4107UBR	Extracellular solute-binding protein family 3
D3H49_RS03045	ENOG4108Q1T	ABC transporter
D3H49_RS03050	ENOG4105DRP	amino acid AbC transporter
D3H49_RS03060	ENOG4108ZUB	Lysine exporter protein (Lyse ygga)
D3H49_RS03065	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D3H49_RS03070	ENOG4105CSR	polyphosphate kinase 2
D3H49_RS03075	ENOG4105CQR	helicase
D3H49_RS03095	ENOG4105F9U	Dehydrogenase
D3H49_RS03115	ENOG4105BZ1	(ABC) transporter
D3H49_RS03140	ENOG4108HKT	sucrose-6-phosphate hydrolase
D3H49_RS03145	ENOG4105U0F	oligosaccharide H symporter, major facilitator superfamily (MFS)
D3H49_RS03165	ENOG4105WH1	Two component transcriptional regulator luxr family
D3H49_RS03185	ENOG4105DWF	phosphomethylpyrimidine kinase
D3H49_RS03195	ENOG4105CBF	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction (By similarity)
D3H49_RS03205	ENOG4105D9H	Catalyzes the attachment of glycine to tRNA(Gly) (By similarity)
D3H49_RS03215	ENOG4105CDK	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (By similarity)
D3H49_RS03250	ENOG4105C0B	DNA polymerase III (alpha subunit)
D3H49_RS03255	ENOG4105M0C	cytoplasmic protein
D3H49_RS03265	ENOG4105CCI	Myosin-Cross-Reactive Antigen
D3H49_RS03315	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D3H49_RS03325	ENOG4105CV8	reductase
D3H49_RS03330	ENOG4105VSY	K01512 acylphosphatase EC 3.6.1.7
D3H49_RS03335	ENOG4105CEK	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (By similarity)
D3H49_RS03340	ENOG4105CIH	Imidazole acetol-phosphate transaminase
D3H49_RS03355	ENOG4108UJE	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (By similarity)
D3H49_RS03360	ENOG4105CJV	Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase
D3H49_RS03375	ENOG4105F27	Major Facilitator
D3H49_RS03380	ENOG4105CQ7	ATP-dependent helicase
D3H49_RS03385	ENOG4105D8J	Specifically methylates the guanine in position 1207 of 16S rRNA in the 30S particle (By similarity)
D3H49_RS03390	ENOG4105C1N	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis (By similarity)
D3H49_RS03415	ENOG4108Z11	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes (By similarity)
D3H49_RS03420	ENOG4108JQ1	Dehydrogenase
D3H49_RS03430	ENOG4108V6E	Cell division protein mraZ
D3H49_RS03445	ENOG4105CJN	penicillin-binding protein
D3H49_RS03500	ENOG4105EDR	glucose galactose transporter
D3H49_RS03515	ENOG4105DKQ	ROK family
D3H49_RS03520	ENOG4105E2R	ROK family
D3H49_RS03525	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
D3H49_RS03530	ENOG4105CE4	GlcNAc 6-P deacetylase
D3H49_RS03540	ENOG4107T6F	Xaa-Pro aminopeptidase
D3H49_RS03545	ENOG4105DPM	folylpolyglutamate synthase Dihydrofolate synthase
D3H49_RS03550	ENOG4105CDB	Required for chromosome condensation and partitioning (By similarity)
D3H49_RS03565	ENOG4107EEN	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan (By similarity)
D3H49_RS03570	ENOG4105EMN	RNA polymerase sigma factor
D3H49_RS03580	ENOG4107WI4	Aldose-1-epimerase
D3H49_RS03585	ENOG4107WI4	Aldose-1-epimerase
D3H49_RS03590	ENOG4105C48	Converts 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate into isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP) (By similarity)
D3H49_RS03595	ENOG4108Z66	YbaK ebsC protein
D3H49_RS03600	ENOG4105C17	glyceraldehyde-3-phosphate dehydrogenase
D3H49_RS03620	ENOG4108UUX	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins (By similarity)
D3H49_RS03640	ENOG4107QQ0	gntp family
D3H49_RS03645	ENOG4105BZW	Glycerate kinase
D3H49_RS03650	ENOG4105C13	Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity)
D3H49_RS03660	ENOG4108KVX	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves (By similarity)
D3H49_RS03665	ENOG4105K8I	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves (By similarity)
D3H49_RS03675	ENOG4105D0I	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate (By similarity)
D3H49_RS03685	ENOG4105D18	nicotinate-nucleotide pyrophosphorylase
D3H49_RS03695	ENOG41079KZ	Major Facilitator Superfamily
D3H49_RS03705	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D3H49_RS03715	ENOG4105CI3	gtp-binding protein typa
D3H49_RS03730	ENOG4105EVN	Prephenate dehydrogenase
D3H49_RS03745	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D3H49_RS03760	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D3H49_RS03765	ENOG4105C2T	Binding-protein-dependent transport systems, inner membrane component
D3H49_RS03770	ENOG4108JQ6	ABC transporter
D3H49_RS03775	ENOG4105CGK	Exodeoxyribonuclease III
D3H49_RS03790	ENOG4105BZT	Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA (By similarity)
D3H49_RS03800	ENOG4105C52	Atpase, p-type (Transporting), had superfamily, subfamily ic
D3H49_RS03815	ENOG4107ZHV	Transcriptional regulator
D3H49_RS03820	ENOG4105HFZ	Membrane
D3H49_RS03860	ENOG4105CEV	competence damage-inducible protein
D3H49_RS03865	ENOG4105WBV	Transcriptional regulator
D3H49_RS03875	ENOG4105C68	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage (By similarity)
D3H49_RS03890	ENOG4108S7Q	sigma 54 modulation protein ribosomal protein S30ea
D3H49_RS03900	ENOG4108I0Q	anthranilate phosphoribosyltransferase
D3H49_RS03915	ENOG4105D9P	serine threonine protein kinase
D3H49_RS03920	ENOG4105EAH	synthase
D3H49_RS03930	ENOG4105DG1	Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released (By similarity)
D3H49_RS03935	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D3H49_RS03945	ENOG4108RVA	ribokinase
D3H49_RS03950	ENOG4107QRT	dEAD DEAH box helicase
D3H49_RS03960	ENOG41075H3	AraC family transcriptional regulator
D3H49_RS03975	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D3H49_RS04000	ENOG4105CWR	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance (By similarity)
D3H49_RS04020	ENOG4107R3N	Filamentation induced by cAMP protein fic
D3H49_RS04060	ENOG4105WEM	extracellular solute-binding protein
D3H49_RS04070	ENOG4105DRS	transport system, permease
D3H49_RS04090	ENOG4107QKS	N-acylglucosamine 2-epimerase
D3H49_RS04125	ENOG4105CVJ	phosphoglycerate mutase
D3H49_RS04130	ENOG4105D7N	magnesium and cobalt transport protein CorA
D3H49_RS04135	ENOG4107UBR	Extracellular solute-binding protein family 3
D3H49_RS04160	ENOG4108097	ATP-binding protein
D3H49_RS04170	ENOG41080E2	ribosomal-protein-alanine acetyltransferase
D3H49_RS04175	ENOG4105CPM	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (By similarity)
D3H49_RS04215	ENOG4105KIU	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
D3H49_RS04220	ENOG4107QJE	Chromosome Partitioning Protein
D3H49_RS04350	ENOG4108KQY	
D3H49_RS04365	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D3H49_RS04385	ENOG41068JE	domain protein
D3H49_RS04470	ENOG4107QVP	Dehydrogenase
D3H49_RS04485	ENOG4108Z02	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D3H49_RS04500	ENOG4105C41	Catalyzes the reversible phosphorylation of UMP to UDP (By similarity)
D3H49_RS04510	ENOG4105KNE	Phosphatidate cytidylyltransferase
D3H49_RS04515	ENOG4105C55	Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs
D3H49_RS04520	ENOG4107RKG	DJ-1/PfpI family
D3H49_RS04555	ENOG4105K78	MarR family Transcriptional regulator
D3H49_RS04565	ENOG4108IQI	permease
D3H49_RS04595	ENOG4105DA5	(ABC) transporter
D3H49_RS04625	ENOG4105DA5	(ABC) transporter
D3H49_RS04680	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D3H49_RS04730	ENOG4108IQI	permease
D3H49_RS04740	ENOG4108RAV	Conserved protein
D3H49_RS04745	ENOG4105CG0	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine (By similarity)
D3H49_RS04750	ENOG4105F6H	The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3- phosphate (By similarity)
D3H49_RS04760	ENOG4105DJV	ribulose-phosphate 3-epimerase
D3H49_RS04770	ENOG4105E21	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (By similarity)
D3H49_RS04795	ENOG4108UW8	fha domain-containing protein
D3H49_RS04820	ENOG4105Q70	
D3H49_RS04845	ENOG410667J	hydrolase
D3H49_RS04855	ENOG4105DKZ	GTPase that plays an essential role in the late steps of ribosome biogenesis (By similarity)
D3H49_RS04860	ENOG4105FE9	pseudouridine synthase
D3H49_RS04865	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D3H49_RS04875	ENOG4105DC1	bifunctional purine biosynthesis protein purh
D3H49_RS04890	ENOG4105CMV	Succinyl-CoA synthetase subunit beta
D3H49_RS04905	ENOG4105CKJ	The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing (By similarity)
D3H49_RS05060	ENOG4107YH6	single-stranded DNA-binding protein
D3H49_RS05070	ENOG4105FA0	parb-like partition protein
D3H49_RS05090	ENOG4108RBP	3'-to-5' exoribonuclease specific for small oligoribonucleotides (By similarity)
D3H49_RS05270	ENOG4105BZ5	ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins (By similarity)
D3H49_RS05285	ENOG4107QQX	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway (By similarity)
D3H49_RS05290	ENOG4105CWM	branched-chain amino acid transport system II carrier protein
D3H49_RS05300	ENOG4105CHM	Aminotransferase
D3H49_RS05340	ENOG4105E2X	shikimate dehydrogenase
D3H49_RS05350	ENOG4105C5U	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate (By similarity)
D3H49_RS05370	ENOG4108RZ4	Short-chain dehydrogenase reductase Sdr
D3H49_RS05375	ENOG4105C5H	ABC transporter
D3H49_RS05390	ENOG4107R11	Transcriptional regulator
D3H49_RS05410	ENOG4107RY0	Catalyzes the conversion of dihydroorotate to orotate (By similarity)
D3H49_RS05415	ENOG4105DF0	Responsible for channeling the electrons from the oxidation of dihydroorotate from the FMN redox center in the PyrD type B subunit to the ultimate electron acceptor NAD( ) (By similarity)
D3H49_RS05420	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
D3H49_RS05425	ENOG4105CD3	dihydroorotase
D3H49_RS05430	ENOG4108R9M	Involved in allosteric regulation of aspartate carbamoyltransferase (By similarity)
D3H49_RS05445	ENOG4107QHE	Choloylglycine hydrolase
D3H49_RS05450	ENOG4105SYT	Methylenetetrahydrofolate reductase
D3H49_RS05460	ENOG4105DKJ	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate (By similarity)
D3H49_RS05480	ENOG4105ETU	transcriptional activator (TenA
D3H49_RS05490	ENOG4108UVJ	appr-1-p processing domain protein
D3H49_RS05495	ENOG4107XM9	(LipO)protein
D3H49_RS05515	ENOG4107QPI	nitrilase cyanide hydratase and apolipoprotein n-acyltransferase
D3H49_RS05575	ENOG4107QPH	glycogen) synthase
D3H49_RS05590	ENOG4108EVY	peptide transport periplasmic protein
D3H49_RS05620	ENOG4105CBC	glutamate synthase
D3H49_RS05630	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS05650	ENOG4105EN6	Membrane
D3H49_RS05660	ENOG4105CM2	brancheD-chain amino acid aminotransferase
D3H49_RS05675	ENOG4105C15	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D3H49_RS05680	ENOG4105W8H	transhydrogenase (subunit alpha
D3H49_RS05685	ENOG4108IIE	The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane (By similarity)
D3H49_RS05690	ENOG4108IQE	Amp-dependent synthetase and ligase
D3H49_RS05715	ENOG4107YU2	histidine triad (hIT) protein
D3H49_RS05720	ENOG4105QF0	Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit (By similarity)
D3H49_RS05740	ENOG4105VG1	fes assembly suf system protein
D3H49_RS05750	ENOG4105C9B	Cysteine desulfurase
D3H49_RS05755	ENOG4105C3K	feS assembly ATPase SufC
D3H49_RS05760	ENOG4105JRK	feS assembly protein SufD
D3H49_RS05775	ENOG4105C8D	Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen (By similarity)
D3H49_RS05780	ENOG4108Z38	Catalyzes a trans-dehydration via an enolate intermediate (By similarity)
D3H49_RS05785	ENOG4105D49	3-dehydroquinate synthase
D3H49_RS05810	ENOG4105CIM	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (By similarity)
D3H49_RS05860	ENOG4108Z86	Glutamine amidotransferase
D3H49_RS05900	ENOG4105VMP	Transcriptional regulator
D3H49_RS05920	ENOG4108RWI	nicotinamidase
D3H49_RS05925	ENOG4107UIE	peptidase
D3H49_RS05940	ENOG4105CB5	ATP-dependent DNA helicase recG
D3H49_RS05955	ENOG4105CJ1	ABC, transporter
D3H49_RS05970	ENOG4108S01	response regulator
D3H49_RS05980	ENOG4105CJ3	phosphate transporter
D3H49_RS05985	ENOG4107R28	alpha amylase, catalytic region
D3H49_RS05990	ENOG4105C1J	atp-dependent rna helicase
D3H49_RS05995	ENOG4105C2W	permease
D3H49_RS06035	ENOG4108VCT	Sulfite exporter TauE/SafE
D3H49_RS06040	ENOG4105C4X	radical SAM domain protein
D3H49_RS06045	ENOG4105CBG	Sulfatase
D3H49_RS06065	ENOG4105E2R	ROK family
D3H49_RS06070	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
D3H49_RS06075	ENOG4105CE4	GlcNAc 6-P deacetylase
D3H49_RS06100	ENOG4105C3G	gtp-binding protein
D3H49_RS06110	ENOG4105DRP	amino acid AbC transporter
D3H49_RS06115	ENOG4105CDA	abc transporter atp-binding protein
D3H49_RS06120	ENOG4105EAB	amino acid AbC transporter
D3H49_RS06125	ENOG4105II7	pyrroline-5-carboxylate reductase
D3H49_RS06140	ENOG4105WH1	Two component transcriptional regulator luxr family
D3H49_RS06145	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D3H49_RS06150	ENOG4105CQU	Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner (By similarity)
D3H49_RS06170	ENOG41080R2	UPF0102 protein
D3H49_RS06175	ENOG4105C0P	Mg chelatase subunit ChlI
D3H49_RS06180	ENOG4105C79	DNA protecting protein DprA
D3H49_RS06185	ENOG4105C00	Succinate dehydrogenase (Flavoprotein subunit)
D3H49_RS06205	ENOG4105DRC	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons (By similarity)
D3H49_RS06210	ENOG4105C87	Aminotransferase class I and II
D3H49_RS06225	ENOG4105CHN	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP (By similarity)
D3H49_RS06230	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D3H49_RS06235	ENOG4105CCQ	Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity)
D3H49_RS06270	ENOG4105C6N	Formate acetyltransferase
D3H49_RS06280	ENOG4105C4K	Nad synthetase
D3H49_RS06285	ENOG4105CH2	amidohydrolase
D3H49_RS06290	ENOG4108UMI	ABC transporter, permease
D3H49_RS06295	ENOG4108JEI	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system (By similarity)
D3H49_RS06300	ENOG4105D01	(LipO)protein
D3H49_RS06320	ENOG4107TB6	phosphoglycerate mutase
D3H49_RS06325	ENOG4105KEM	Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation (By similarity)
D3H49_RS06330	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D3H49_RS06340	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D3H49_RS06345	ENOG4105EXC	Acyl-transferase
D3H49_RS06350	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D3H49_RS06360	ENOG4105C6K	Malic enzyme
D3H49_RS06365	ENOG4105C6H	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction (By similarity)
D3H49_RS06390	ENOG4105CM0	Catalyzes the synthesis of GMP from XMP (By similarity)
D3H49_RS06415	ENOG4105EJF	Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage (By similarity)
D3H49_RS06420	ENOG4105EGD	dinuclear metal center protein, YbgI family
D3H49_RS06440	ENOG4108YZ4	nudix hydrolase
D3H49_RS06445	ENOG4105CA9	Pyruvate kinase
D3H49_RS06455	ENOG4105CCW	damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage (By similarity)
D3H49_RS06460	ENOG4108ZQD	Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A (By similarity)
D3H49_RS06465	ENOG4105CAV	thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence (By similarity)
D3H49_RS06480	ENOG4105DIK	(ABC) transporter
D3H49_RS06500	ENOG4105C9C	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position (By similarity)
D3H49_RS06505	ENOG4105CK6	Two component transcriptional regulator (Winged helix family
D3H49_RS06510	ENOG4105EB3	Histidine kinase
D3H49_RS06515	ENOG4107VCP	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP) (By similarity)
D3H49_RS06540	ENOG4105K51	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
D3H49_RS06545	ENOG4108KGH	TRANSCRIPTIONal
D3H49_RS06550	ENOG4105EC2	ftsk spoIIIe
D3H49_RS06555	ENOG4105KRM	Acts as a transcriptional regulator. Probably redox- responsive. The apo- but not holo-form probably binds DNA (By similarity)
D3H49_RS06565	ENOG4108UT2	hemolysin iii
D3H49_RS06580	ENOG4105EJQ	L-serine dehydratase
D3H49_RS06615	ENOG4105CPC	Aldo Keto reductase
D3H49_RS06635	ENOG4105DJZ	UPF0182 protein
D3H49_RS06645	ENOG4108Z1W	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD) (By similarity)
D3H49_RS06660	ENOG4105D98	threonine synthase
D3H49_RS06710	ENOG4107UW8	HAD-superfamily hydrolase subfamily IA variant 3
D3H49_RS06715	ENOG4105C4F	May be involved in recombinational repair of damaged DNA (By similarity)
D3H49_RS06770	ENOG4105M78	Catalyzes, although with low efficiency, the sulfur transfer reaction from thiosulfate to cyanide (By similarity)
D3H49_RS06775	ENOG4105D06	uba thif-type nad fad binding protein
D3H49_RS06780	ENOG4105CA8	Catalyzes the rearrangement of 1-deoxy-D-xylulose 5- phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S (By similarity)
D3H49_RS06800	ENOG4105KRQ	Addiction module toxin, Txe YoeB family
D3H49_RS06845	ENOG4105C8Y	Acetylornithine aminotransferase
D3H49_RS06855	ENOG4105C5V	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate (By similarity)
D3H49_RS06870	ENOG4105C6A	phenylalanyl-tRNA synthetase (beta subunit)
D3H49_RS06875	ENOG4105CSS	phenylalanyl-tRNA synthetase (alpha subunit)
D3H49_RS06880	ENOG4108RWN	rrna methyltransferase
D3H49_RS06890	ENOG4108JJB	ABC transporter
D3H49_RS06895	ENOG4105NSK	ABC superfamily ATP binding cassette transporter membrane protein
D3H49_RS06900	ENOG4105C9Y	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls (By similarity)
D3H49_RS06945	ENOG4108JJB	ABC transporter
D3H49_RS06960	ENOG4105EUS	Binding-protein-dependent transport systems, inner membrane component
D3H49_RS06965	ENOG4105CR3	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids (By similarity)
D3H49_RS06980	ENOG4105C4E	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate (By similarity)
D3H49_RS07040	ENOG4105E4Z	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan (By similarity)
D3H49_RS07075	ENOG4105C28	cystathionine
D3H49_RS07095	ENOG4105DE5	Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity (By similarity)
D3H49_RS07100	ENOG4108UHA	Essential for recycling GMP and indirectly, cGMP (By similarity)
D3H49_RS07105	ENOG4105SKN	orotidine 5''-phosphate decarboxylase
D3H49_RS07115	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D3H49_RS07130	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D3H49_RS07140	ENOG4108KHX	Diguanylate cyclase
D3H49_RS07150	ENOG4107QZ7	Cellulose synthase catalytic subunit
D3H49_RS07165	ENOG4108UW5	maltose o-acetyltransferase
D3H49_RS07170	ENOG4108UW5	maltose o-acetyltransferase
D3H49_RS07210	ENOG4105CPQ	Dehydrogenase
D3H49_RS07225	ENOG4108BVP	Protein CrcB homolog
D3H49_RS07235	ENOG4107TGP	family UPF0324
D3H49_RS07265	ENOG4108UKE	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit (By similarity)
D3H49_RS07270	ENOG4105C09	Bile acid
D3H49_RS07290	ENOG4105CHM	Aminotransferase
D3H49_RS07295	ENOG4108HH9	Catalyzes two reactions the first one is the production of beta-formyl glycinamide ribonucleotide (GAR) from formate, ATP and beta GAR
D3H49_RS07365	ENOG4105CQ3	Poorly processive error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits no 3-5 exonuclease (proofreading) activity. May be involved in translesional synthesis in conjunction with the beta clamp from polIII (By similarity)
D3H49_RS07370	ENOG4105CBA	glutamine phosphoribosylpyrophosphate amidotransferase
D3H49_RS07385	ENOG4105C26	Dehydrogenase
D3H49_RS07415	ENOG4108PJD	permease
D3H49_RS07460	ENOG4105CY8	phosphoribosylaminoimidazole carboxylase atpase subunit
D3H49_RS07465	ENOG4108UM6	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (By similarity)
D3H49_RS07470	ENOG4105CB2	alcohol dehydrogenase
D3H49_RS07475	ENOG4105C2V	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP) (By similarity)
D3H49_RS07480	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D3H49_RS07490	ENOG4105D6C	Part of the ABC transporter complex MacAB involved in macrolide export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation (By similarity)
D3H49_RS07505	ENOG4105E0X	reductase
D3H49_RS07520	ENOG4105CG3	alpha amylase, catalytic region
D3H49_RS07525	ENOG4107P2S	Transcriptional regulator
D3H49_RS07560	ENOG4105F4P	)-transporter
D3H49_RS07565	ENOG4105C1I	TRANSCRIPTIONAl REGULATOR GntR family
D3H49_RS07570	ENOG4108UHX	Involved in the hydrolysis of glutamine to glutamate and ammonia. Channels an ammonia molecule to PdxS (By similarity)
D3H49_RS07575	ENOG4105CD9	Involved in the production of pyridoxal phosphate, probably by incorporating ammonia into the pyridine ring (By similarity)
D3H49_RS07590	ENOG4105C9G	DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments on both template strands at replication forks during chromosomal DNA synthesis (By similarity)
D3H49_RS07595	ENOG4105C4Q	deoxyguanosinetriphosphate triphosphohydrolase-like protein
D3H49_RS07600	ENOG4105CJ4	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids (By similarity)
D3H49_RS07605	ENOG4105CUB	amino acid
D3H49_RS07620	ENOG4105C9U	ATP-dependent DNA helicase RecQ
D3H49_RS07625	ENOG4105C28	cystathionine
D3H49_RS07635	ENOG4108JQ7	(ABC) transporter
D3H49_RS07650	ENOG4105CJM	Binding-protein-dependent transport systems, inner membrane component
D3H49_RS07680	ENOG4105DRS	transport system, permease
D3H49_RS07690	ENOG4105FKQ	transcriptional regulator
D3H49_RS07695	ENOG4105D3G	Pseudouridine synthase
D3H49_RS07705	ENOG4105CDA	abc transporter atp-binding protein
D3H49_RS07730	ENOG41068JE	domain protein
D3H49_RS07735	ENOG4105CRP	Part of the ABC transporter FtsEX involved in
D3H49_RS07740	ENOG4105CAK	Cell division ATP-binding protein ftsE
D3H49_RS07745	ENOG4105CG1	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA (By similarity)
D3H49_RS07755	ENOG4108RBJ	Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions (By similarity)
D3H49_RS07770	ENOG4105CN5	Metallo-Beta-Lactamase
D3H49_RS07780	ENOG4105DUK	Catalyzes the conversion of 4-hydroxy- tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate (By similarity)
D3H49_RS07790	ENOG4105C4R	Atp-dependent dna helicase
D3H49_RS07805	ENOG4105C7R	Atpase associated with various cellular activities aaa_3
D3H49_RS07840	ENOG4108UIQ	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide (By similarity)
D3H49_RS07845	ENOG4105CAG	UPF0210 protein
D3H49_RS07850	ENOG4105VUC	UPF0237 protein
D3H49_RS07855	ENOG4105CRD	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P) (By similarity)
D3H49_RS07865	ENOG4105MVE	transcriptional regulator
D3H49_RS07870	ENOG4107QYT	Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor (By similarity)
D3H49_RS07875	ENOG4105CCY	NADH flavin oxidoreductase, NADH oxidase
D3H49_RS07880	ENOG4105BZ4	penicillin-binding protein
D3H49_RS07885	ENOG4105IJJ	transcriptional regulator, crp fnr family
D3H49_RS07890	ENOG4105DF9	Lipoate-protein, ligase
D3H49_RS07910	ENOG4105KE9	The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein (By similarity)
D3H49_RS07950	ENOG4107YJ4	chain length determinant protein
D3H49_RS07985	ENOG4105F5W	AtP-binding protein
D3H49_RS08010	ENOG4105K64	Glycosyl transferase, family 2
D3H49_RS08020	ENOG4105CAJ	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (By similarity)
D3H49_RS08040	ENOG4108KMV	Glycosyl transferase (Group 1
D3H49_RS08050	ENOG4107ZF2	Phosphatase
D3H49_RS08055	ENOG4105D3Q	Sugar transferase
D3H49_RS08085	ENOG4105CV8	reductase
D3H49_RS08100	ENOG4105C4C	beta-galactosidase
D3H49_RS08105	ENOG4105DRS	transport system, permease
D3H49_RS08115	ENOG4108JE9	extracellular solute-binding protein family 1
D3H49_RS08125	ENOG4108JJ9	ABC, transporter
D3H49_RS08140	ENOG4107QNK	)-transporter
D3H49_RS08155	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS08160	ENOG4108UH2	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids (By similarity)
D3H49_RS08170	ENOG4108YY1	This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site (By similarity)
D3H49_RS08185	ENOG4107QP8	phosphohexose isomerase
D3H49_RS08210	ENOG4105ED0	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates (By similarity)
D3H49_RS08230	ENOG4105CPC	Aldo Keto reductase
D3H49_RS08260	ENOG4108ZBM	Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Also processes some mRNAs, and tRNAs when they are encoded in the rRNA operon (By similarity)
D3H49_RS08270	ENOG4108ZP8	Acetolactate synthase small subunit
D3H49_RS08285	ENOG4105C5H	ABC transporter
D3H49_RS08300	ENOG4105C1M	carbamoyl-phosphate synthetase glutamine chain
D3H49_RS08305	ENOG4105C8N	cysteinyl-tRNA synthetase
D3H49_RS08325	ENOG4105K5M	30s ribosomal protein S16
D3H49_RS08330	ENOG41084QK	UPF0109 protein
D3H49_RS08365	ENOG4108V0P	LemA family
D3H49_RS08435	ENOG4105R3C	Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein (By similarity)
D3H49_RS08440	ENOG4105K85	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) in DNA. Repairs alkylated guanine in DNA by stoichiometrically transferring the alkyl group at the O-6 position to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated (By similarity)
D3H49_RS08465	ENOG4105E4P	ATPase (AAA
D3H49_RS08470	ENOG4105DRS	transport system, permease
D3H49_RS08485	ENOG4105ENH	Sulfatase
D3H49_RS08490	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS08495	ENOG4105C4X	radical SAM domain protein
D3H49_RS08500	ENOG4108VCT	Sulfite exporter TauE/SafE
D3H49_RS08510	ENOG4108IJ0	Aspartate ammonia-lyase
D3H49_RS08525	ENOG4105C53	Part of the ABC transporter complex PotABCD involved in spermidine putrescine import. Responsible for energy coupling to the transport system (By similarity)
D3H49_RS08545	ENOG4105CPF	Cell wall formation (By similarity)
D3H49_RS08560	ENOG4105KME	endoribonuclease L-psp
D3H49_RS08600	ENOG410825K	Produces ATP from ADP in the presence of a proton gradient across the membrane (By similarity)
D3H49_RS08635	ENOG4107UH5	it plays a direct role in the translocation of protons across the membrane (By similarity)
D3H49_RS08640	ENOG4105CVG	Homoserine O-transsuccinylase
D3H49_RS08655	ENOG4105EP6	Maltosyltransferase that uses maltose 1-phosphate (M1P) as the sugar donor to elongate linear or branched alpha-(1- 4)- glucans. Is involved in a branched alpha-glucan biosynthetic pathway from trehalose, together with TreS, Mak and GlgB (By similarity)
D3H49_RS08660	ENOG4105F0N	pyrophosphate phospho-hydrolase
D3H49_RS08675	ENOG4107NHD	transcriptional regulator
D3H49_RS08715	ENOG4105DRS	transport system, permease
D3H49_RS08730	ENOG4108R6W	Transcriptional regulator, ARAC family
D3H49_RS08775	ENOG41081AP	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln) (By similarity)
D3H49_RS08790	ENOG4105CJ1	ABC, transporter
D3H49_RS08805	ENOG4105CGY	Dna recombination protein
D3H49_RS08810	ENOG4105VPX	protein, conserved in bacteria
D3H49_RS08820	ENOG4105D8C	Channel that permits osmotically driven movement of water in both directions. It is involved in the osmoregulation and in the maintenance of cell turgor during volume expansion in rapidly growing cells. It mediates rapid entry or exit of water in response to abrupt changes in osmolarity (By similarity)
D3H49_RS08835	ENOG4105VH8	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit (By similarity)
D3H49_RS08840	ENOG4107YH6	single-stranded DNA-binding protein
D3H49_RS08845	ENOG410829C	Binds together with S18 to 16S ribosomal RNA (By similarity)
D3H49_RS08850	ENOG4105C5T	Phosphoribosyl pyrophosphate synthase
D3H49_RS08855	ENOG4105DFA	alanine racemase domain protein
D3H49_RS08880	ENOG4105F1K	Glutamine amidotransferase
D3H49_RS08885	ENOG4105DMS	mur ligase
D3H49_RS08890	ENOG4105CDU	Replicative dna helicase
D3H49_RS08900	ENOG4105E1P	Modifies, by uridylylation or deuridylylation the PII (GlnB) regulatory protein (By similarity)
D3H49_RS08915	ENOG4105CCP	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC)
D3H49_RS08920	ENOG41067SE	Tetr family transcriptional regulator
D3H49_RS08930	ENOG4105DZW	Dipeptidase
D3H49_RS08955	ENOG4107XU2	6-phosphogluconolactonase (EC 3.1.1.31)
D3H49_RS08960	ENOG4105C7Q	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH (By similarity)
D3H49_RS08990	ENOG4105C19	ABC transporter
D3H49_RS08995	ENOG4107R34	abc transporter permease protein
D3H49_RS09010	ENOG4108SDV	Periplasmic Protein
D3H49_RS09015	ENOG4107SJW	iron permease, FTR1
D3H49_RS09085	ENOG4108RYK	Nad-dependent epimerase dehydratase
D3H49_RS09090	ENOG4105KVH	Transcriptional regulator
D3H49_RS09095	ENOG4105XPP	Protein of unknown function (DUF1275)
D3H49_RS09155	ENOG4105CKU	formyltetrahydrofolate synthetase
D3H49_RS09160	ENOG4105DZW	Dipeptidase
D3H49_RS09175	ENOG4105BZ3	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr) (By similarity)
D3H49_RS09190	ENOG4105C6E	dna polymerase iii
D3H49_RS09200	ENOG4105C73	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone (By similarity)
D3H49_RS09215	ENOG4108JQC	penicillin-binding protein 1A
D3H49_RS09230	ENOG4107YCY	Transcriptional regulator
D3H49_RS09250	ENOG4105CKA	Catalyzes the reversible isomerization-deamination of glucosamine 6-phosphate (GlcN6P) to form fructose 6-phosphate (Fru6P) and ammonium ion (By similarity)
D3H49_RS09255	ENOG4105CDP	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA) (By similarity)
D3H49_RS09260	ENOG4108JQ7	(ABC) transporter
D3H49_RS09285	ENOG4105C9S	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P) (By similarity)
D3H49_RS09290	ENOG4107TFG	D-allose kinase
D3H49_RS09305	ENOG4107QK3	aspartate-semialdehyde dehydrogenase (EC 1.2.1.11
D3H49_RS09310	ENOG4105CFH	Aspartokinase
D3H49_RS09315	ENOG4105CFH	Aspartokinase
D3H49_RS09355	ENOG4108WUH	Transcriptional regulator, TetR family
D3H49_RS09400	ENOG4105DQR	SNARE associated Golgi
D3H49_RS09405	ENOG4105MN5	HAD-superfamily hydrolase subfamily IA variant 3
D3H49_RS09410	ENOG4105CHR	reductase
D3H49_RS09425	ENOG4105KNI	merR family transcriptional Regulator
D3H49_RS09435	ENOG4108093	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
D3H49_RS09445	ENOG4108IUM	Glycogen debranching enzyme
D3H49_RS09460	ENOG4105EG2	ABC transporter, permease
D3H49_RS09500	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS09505	ENOG4105CG3	alpha amylase, catalytic region
D3H49_RS09510	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D3H49_RS09515	ENOG4105C6M	Alpha-keto-beta-hydroxylacyl reductoisomerase
D3H49_RS09520	ENOG4105CSH	Transporter
D3H49_RS09525	ENOG4105ETE	Transcriptional regulator (LacI family
D3H49_RS09535	ENOG4107RK0	Sucrose phosphorylase
D3H49_RS09555	ENOG4105CMQ	Chloride channel
D3H49_RS09565	ENOG4107RCW	fructose-bisphosphate aldolase
D3H49_RS09570	ENOG4108RNG	Permease of the drug metabolite transporter
D3H49_RS09580	ENOG4105D0M	Protease HtpX homolog
D3H49_RS09595	ENOG4105C0H	protease
D3H49_RS09600	ENOG4105C6U	Exchanges the guanine residue with 7-aminomethyl-7- deazaguanine in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). After this exchange, a cyclopentendiol moiety is attached to the 7-aminomethyl group of 7-deazaguanine, resulting in the hypermodified nucleoside queuosine (Q) (7-(((4,5-cis- dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine) (By similarity)
D3H49_RS09620	ENOG4105M6F	mutator MutT protein
D3H49_RS09650	ENOG4105E0X	reductase
D3H49_RS09655	ENOG4105FF5	Membrane
D3H49_RS09660	ENOG4108SEA	Esterase
D3H49_RS09670	ENOG4105RPH	Inner membrane protein YddG
D3H49_RS09675	ENOG4107Y70	Heat shock protein
D3H49_RS09710	ENOG4105CJN	penicillin-binding protein
D3H49_RS09715	ENOG4107TPY	serine threonine protein kinase
D3H49_RS09720	ENOG4105D9P	serine threonine protein kinase
D3H49_RS09740	ENOG4105ZJT	Cell division protein CrgA
D3H49_RS09770	ENOG4105C31	Tryptophanyl-tRNA synthetase
D3H49_RS09795	ENOG4105CCA	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle (By similarity)
D3H49_RS09860	ENOG4105D3R	alkyl hydroperoxide reductase
D3H49_RS09880	ENOG4105DPV	During stationary phase, binds the chromosome non- specifically, forming a highly ordered and stable dps-DNA co- crystal within which chromosomal DNA is condensed and protected from diverse damages. It protects DNA from oxidative damage by sequestering intracellular Fe(2 ) ion and storing it in the form of Fe(3 ) oxyhydroxide mineral, which can be released after reduction. One hydrogen peroxide oxidizes two Fe(2 ) ions, which prevents hydroxyl radical production by the Fenton reaction
D3H49_RS09915	ENOG4107R37	Glutamate dehydrogenase
D3H49_RS09925	ENOG4105CNT	hydrolase family 2
D3H49_RS09935	ENOG4105CQ4	Transcriptional regulator
D3H49_RS09945	ENOG4105C24	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D3H49_RS09950	ENOG4105C7D	DNA gyrase negatively supercoils closed circular double- stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings (By similarity)
D3H49_RS09955	ENOG4105K7N	UPF0232 protein
D3H49_RS09965	ENOG4105CZ8	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity. The beta chain is required for initiation of replication once it is clamped onto DNA, it slides freely (bidirectional and ATP- independent) along duplex DNA (By similarity)