locus-tag	class	description
GFJ40_RS00010	COG0592	DNA-directed DNA polymerase activity
GFJ40_RS00025	COG0187	DNA topoisomerase II activity
GFJ40_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFJ40_RS00040	COG1609	Transcriptional regulator
GFJ40_RS00050	COG3250	beta-galactosidase activity
GFJ40_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GFJ40_RS00100	COG0783	Belongs to the Dps family
GFJ40_RS00120	COG1609	Transcriptional regulator
GFJ40_RS00140	COG1609	Transcriptional regulator
GFJ40_RS00185	COG1609	Transcriptional regulator
GFJ40_RS00195	COG0783	Belongs to the Dps family
GFJ40_RS00200	COG1253	flavin adenine dinucleotide binding
GFJ40_RS00265	COG3706	GGDEF domain
GFJ40_RS00265	COG2203	Gaf domain
GFJ40_RS00265	COG4251	negative regulation of phosphorylation
GFJ40_RS00265	COG5001	Diguanylate cyclase
GFJ40_RS00285	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GFJ40_RS00295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GFJ40_RS00310	COG0180	Tryptophanyl-tRNA synthetase
GFJ40_RS00320	COG2197	response regulator
GFJ40_RS00340	COG0058	SHG alpha-glucan phosphorylase activity
GFJ40_RS00380	COG0515	serine threonine protein kinase
GFJ40_RS00385	COG0768	penicillin binding
GFJ40_RS00420	COG0071	Belongs to the small heat shock protein (HSP20) family
GFJ40_RS00425	COG0697	spore germination
GFJ40_RS00435	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
GFJ40_RS00440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GFJ40_RS00470	COG0494	nUDIX hydrolase
GFJ40_RS00490	COG0343	queuine tRNA-ribosyltransferase activity
GFJ40_RS00520	COG0697	spore germination
GFJ40_RS00525	COG0191	fructose-bisphosphate aldolase activity
GFJ40_RS00565	COG1609	Transcriptional regulator
GFJ40_RS00570	COG0477	Major facilitator Superfamily
GFJ40_RS00595	COG0366	Alpha amylase catalytic
GFJ40_RS00600	COG1609	Transcriptional regulator
GFJ40_RS00635	COG1175	transmembrane transport
GFJ40_RS00640	COG3833	ABC-type maltose transport systems, permease component
GFJ40_RS00655	COG1523	belongs to the glycosyl hydrolase 13 family
GFJ40_RS00675	COG0789	Transcriptional regulator
GFJ40_RS00690	COG1028	Short-chain dehydrogenase reductase Sdr
GFJ40_RS00695	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFJ40_RS00700	COG0586	Pfam SNARE associated Golgi protein
GFJ40_RS00745	COG1309	transcriptional regulator
GFJ40_RS00785	COG0527	aspartate kinase activity
GFJ40_RS00805	COG1940	carbohydrate kinase activity
GFJ40_RS00810	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
GFJ40_RS00820	COG0747	negative chemotaxis
GFJ40_RS00830	COG0444	Belongs to the ABC transporter superfamily
GFJ40_RS00835	COG4608	Belongs to the ABC transporter superfamily
GFJ40_RS00840	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFJ40_RS00865	COG2186	Transcriptional regulator
GFJ40_RS00900	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GFJ40_RS00900	COG1754	DNA topoisomerase type I activity
GFJ40_RS00910	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GFJ40_RS00925	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GFJ40_RS01005	COG3619	membrane
GFJ40_RS01010	COG1733	regulation of RNA biosynthetic process
GFJ40_RS01015	COG2910	NAD(P)H-binding
GFJ40_RS01030	COG0477	Major facilitator Superfamily
GFJ40_RS01035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GFJ40_RS01040	COG0604	alcohol dehydrogenase
GFJ40_RS01040	COG3321	synthase
GFJ40_RS01040	COG1028	Short-chain dehydrogenase reductase Sdr
GFJ40_RS01050	COG2977	Belongs to the P-Pant transferase superfamily
GFJ40_RS01125	COG0672	)-iron permease
GFJ40_RS01130	COG3470	protein probably involved in high-affinity Fe2 transport
GFJ40_RS01145	COG0577	efflux transmembrane transporter activity
GFJ40_RS01150	COG1136	(ABC) transporter
GFJ40_RS01180	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GFJ40_RS01185	COG0363	glucosamine-6-phosphate deaminase activity
GFJ40_RS01215	COG1442	glycosyl transferase family 8
GFJ40_RS01215	COG1216	Glycosyl transferase, family 2
GFJ40_RS01220	COG1309	transcriptional regulator
GFJ40_RS01240	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GFJ40_RS01250	COG0305	Participates in initiation and elongation during chromosome replication
GFJ40_RS01255	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFJ40_RS01260	COG3442	glutamine amidotransferase
GFJ40_RS01295	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GFJ40_RS01345	COG1131	(ABC) transporter
GFJ40_RS01380	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
GFJ40_RS01390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GFJ40_RS01400	COG1937	Protein conserved in bacteria
GFJ40_RS01420	COG1131	(ABC) transporter
GFJ40_RS01485	COG2182	Extracellular solute-binding protein
GFJ40_RS01495	COG0395	ABC-type sugar transport system, permease component
GFJ40_RS01535	COG0745	RESPONSE REGULATOR receiver
GFJ40_RS01550	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GFJ40_RS01575	COG0356	it plays a direct role in the translocation of protons across the membrane
GFJ40_RS01610	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GFJ40_RS01650	COG0251	oxidation-reduction process
GFJ40_RS01685	COG3842	ATPase activity
GFJ40_RS01700	COG1027	Aspartate ammonia-lyase
GFJ40_RS01710	COG0730	response to heat
GFJ40_RS01715	COG0641	radical SAM
GFJ40_RS01720	COG1609	Transcriptional regulator
GFJ40_RS01725	COG3119	arylsulfatase activity
GFJ40_RS01740	COG0395	ABC-type sugar transport system, permease component
GFJ40_RS01745	COG1373	ATPase (AAA superfamily
GFJ40_RS01765	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GFJ40_RS01780	COG0569	domain protein
GFJ40_RS01780	COG0475	glutathione-regulated potassium exporter activity
GFJ40_RS01830	COG1136	(ABC) transporter
GFJ40_RS01840	COG1704	LemA family
GFJ40_RS01875	COG1837	Belongs to the UPF0109 family
GFJ40_RS01905	COG0505	Belongs to the CarA family
GFJ40_RS01920	COG0488	(ABC) transporter
GFJ40_RS01925	COG1487	ribonuclease activity
GFJ40_RS01935	COG0440	acetolactate synthase activity
GFJ40_RS01975	COG0667	Aldo Keto reductase
GFJ40_RS02025	COG1116	anion transmembrane transporter activity
GFJ40_RS02045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GFJ40_RS02050	COG1609	Transcriptional regulator
GFJ40_RS02065	COG0477	Major facilitator Superfamily
GFJ40_RS02065	COG2814	Major facilitator Superfamily
GFJ40_RS02075	COG4988	ABC transporter
GFJ40_RS02085	COG1653	transport
GFJ40_RS02105	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GFJ40_RS02115	COG0656	L-ascorbic acid biosynthetic process
GFJ40_RS02135	COG2814	Major facilitator Superfamily
GFJ40_RS02150	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFJ40_RS02180	COG1216	Glycosyl transferase, family 2
GFJ40_RS02190	COG1215	transferase activity, transferring glycosyl groups
GFJ40_RS02200	COG0438	transferase activity, transferring glycosyl groups
GFJ40_RS02205	COG0438	transferase activity, transferring glycosyl groups
GFJ40_RS02220	COG1442	glycosyl transferase family 8
GFJ40_RS02220	COG1216	Glycosyl transferase, family 2
GFJ40_RS02225	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GFJ40_RS02235	COG1216	Glycosyl transferase, family 2
GFJ40_RS02260	COG1484	DNA-dependent DNA replication
GFJ40_RS02345	COG0489	protein tyrosine kinase activity
GFJ40_RS02400	COG0095	Lipoate-protein ligase
GFJ40_RS02405	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GFJ40_RS02410	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GFJ40_RS02410	COG4499	WXG100 protein secretion system (Wss), protein YukC
GFJ40_RS02415	COG1902	pentaerythritol trinitrate reductase activity
GFJ40_RS02420	COG0167	dihydroorotate dehydrogenase activity
GFJ40_RS02425	COG1349	DNA-binding transcription factor activity
GFJ40_RS02435	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GFJ40_RS02450	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GFJ40_RS02485	COG0714	Associated with various cellular activities
GFJ40_RS02500	COG0210	DNA helicase
GFJ40_RS02520	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GFJ40_RS02545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GFJ40_RS02550	COG2884	Cell division ATP-binding protein ftsE
GFJ40_RS02555	COG2177	Part of the ABC transporter FtsEX involved in
GFJ40_RS02560	COG1388	LysM domain
GFJ40_RS02560	COG3942	CHAP domain
GFJ40_RS02585	COG1126	abc transporter atp-binding protein
GFJ40_RS02595	COG0564	pseudouridine synthase activity
GFJ40_RS02605	COG1175	transmembrane transport
GFJ40_RS02620	COG1653	transport
GFJ40_RS02640	COG0601	transmembrane transport
GFJ40_RS02645	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFJ40_RS02655	COG4608	Belongs to the ABC transporter superfamily
GFJ40_RS02665	COG0626	cystathionine gamma-synthase activity
GFJ40_RS02670	COG0514	ATP-dependent DNA helicase (RecQ)
GFJ40_RS02685	COG0531	amino acid
GFJ40_RS02690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GFJ40_RS02700	COG0358	DNA primase activity
GFJ40_RS02715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFJ40_RS02720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GFJ40_RS02755	COG1609	Transcriptional regulator
GFJ40_RS02760	COG0366	Alpha amylase catalytic
GFJ40_RS02790	COG0577	efflux transmembrane transporter activity
GFJ40_RS02790	COG1136	(ABC) transporter
GFJ40_RS02800	COG0577	efflux transmembrane transporter activity
GFJ40_RS02800	COG0577	efflux transmembrane transporter activity
GFJ40_RS02805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GFJ40_RS02810	COG0604	alcohol dehydrogenase
GFJ40_RS02815	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GFJ40_RS02820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GFJ40_RS02840	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GFJ40_RS02865	COG0701	Predicted permease
GFJ40_RS02880	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GFJ40_RS02890	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GFJ40_RS02895	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GFJ40_RS02900	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GFJ40_RS02920	COG1012	belongs to the aldehyde dehydrogenase family
GFJ40_RS02940	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFJ40_RS02970	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GFJ40_RS02985	COG0436	Aminotransferase
GFJ40_RS03005	COG0385	Bile acid
GFJ40_RS03035	COG0583	DNA-binding transcription factor activity
GFJ40_RS03065	COG1063	alcohol dehydrogenase
GFJ40_RS03120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFJ40_RS03145	COG0110	maltose O-acetyltransferase activity
GFJ40_RS03180	COG0390	transport system, permease component
GFJ40_RS03185	COG1132	(ABC) transporter
GFJ40_RS03210	COG0284	orotidine-5'-phosphate decarboxylase activity
GFJ40_RS03220	COG2176	DNA-directed DNA polymerase activity
GFJ40_RS03240	COG0626	cystathionine gamma-synthase activity
GFJ40_RS03275	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GFJ40_RS03355	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GFJ40_RS03370	COG1122	ATPase activity
GFJ40_RS03410	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFJ40_RS03420	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFJ40_RS03425	COG4721	ABC-type cobalt transport system, permease component
GFJ40_RS03430	COG1122	ATPase activity
GFJ40_RS03440	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFJ40_RS03505	COG4115	mRNA cleavage
GFJ40_RS03530	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GFJ40_RS03535	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GFJ40_RS03595	COG0497	DNA recombination
GFJ40_RS03650	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GFJ40_RS03680	COG0667	Aldo Keto reductase
GFJ40_RS03715	COG1760	l-serine dehydratase
GFJ40_RS03725	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GFJ40_RS03750	COG1316	TRANSCRIPTIONal
GFJ40_RS03790	COG2205	protein histidine kinase activity
GFJ40_RS03795	COG0745	RESPONSE REGULATOR receiver
GFJ40_RS03815	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GFJ40_RS03820	COG1121	(ABC) transporter
GFJ40_RS03835	COG0539	negative regulation of cytoplasmic translation
GFJ40_RS03855	COG0469	pyruvate kinase activity
GFJ40_RS03860	COG0494	nUDIX hydrolase
GFJ40_RS03880	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GFJ40_RS03885	COG1051	belongs to the nudix hydrolase family
GFJ40_RS03935	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GFJ40_RS03940	COG0857	belongs to the CobB CobQ family
GFJ40_RS03940	COG0280	phosphate acetyltransferase
GFJ40_RS03975	COG0799	negative regulation of ribosome biogenesis
GFJ40_RS03980	COG0406	alpha-ribazole phosphatase activity
GFJ40_RS04010	COG2011	ABC-type metal ion transport system permease component
GFJ40_RS04015	COG1473	amidohydrolase
GFJ40_RS04030	COG1882	Formate acetyltransferase
GFJ40_RS04090	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GFJ40_RS04095	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GFJ40_RS04100	COG1611	Belongs to the LOG family
GFJ40_RS04115	COG1053	succinate dehydrogenase
GFJ40_RS04120	COG0758	DNA mediated transformation
GFJ40_RS04145	COG2873	o-acetylhomoserine
GFJ40_RS04150	COG1136	(ABC) transporter
GFJ40_RS04155	COG0577	efflux transmembrane transporter activity
GFJ40_RS04155	COG1136	(ABC) transporter
GFJ40_RS04160	COG2197	response regulator
GFJ40_RS04175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GFJ40_RS04180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFJ40_RS04185	COG1126	abc transporter atp-binding protein
GFJ40_RS04190	COG0765	amino acid transport
GFJ40_RS04195	COG0765	amino acid transport
GFJ40_RS04200	COG0012	GTP binding
GFJ40_RS04220	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GFJ40_RS04230	COG3177	Filamentation induced by cAMP protein fic
GFJ40_RS04275	COG1309	transcriptional regulator
GFJ40_RS04285	COG2814	Major facilitator Superfamily
GFJ40_RS04310	COG1846	Transcriptional regulator
GFJ40_RS04310	COG1940	carbohydrate kinase activity
GFJ40_RS04325	COG0477	Major facilitator Superfamily
GFJ40_RS04330	COG3119	arylsulfatase activity
GFJ40_RS04335	COG0641	radical SAM
GFJ40_RS04340	COG0730	response to heat
GFJ40_RS04380	COG2233	PERMEase
GFJ40_RS04385	COG0513	Belongs to the DEAD box helicase family
GFJ40_RS04390	COG0366	Alpha amylase catalytic
GFJ40_RS04395	COG0306	phosphate transporter
GFJ40_RS04405	COG2197	response regulator
GFJ40_RS04410	COG4585	Histidine kinase
GFJ40_RS04415	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFJ40_RS04420	COG1131	(ABC) transporter
GFJ40_RS04450	COG3340	Belongs to the peptidase S51 family
GFJ40_RS04455	COG1335	isochorismatase
GFJ40_RS04475	COG3655	Transcriptional regulator
GFJ40_RS04515	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GFJ40_RS04595	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GFJ40_RS04615	COG0719	Fe-S assembly protein
GFJ40_RS04620	COG0396	ATPase activity
GFJ40_RS04625	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GFJ40_RS04635	COG2151	metal-sulfur cluster biosynthetic enzyme
GFJ40_RS04655	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GFJ40_RS04660	COG0537	adenosine 5'-monophosphoramidase activity
GFJ40_RS04685	COG1022	Amp-dependent synthetase and ligase
GFJ40_RS04690	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GFJ40_RS04715	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GFJ40_RS04725	COG2860	membrane
GFJ40_RS04755	COG0069	glutamate synthase activity
GFJ40_RS04755	COG0067	glutamate synthase
GFJ40_RS04755	COG0070	glutamate synthase
GFJ40_RS04765	COG4166	transmembrane transport
GFJ40_RS04780	COG0297	glycogen (starch) synthase activity
GFJ40_RS04785	COG1119	ATPase activity
GFJ40_RS04825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GFJ40_RS04890	COG1073	alpha beta
GFJ40_RS04895	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
GFJ40_RS04905	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
GFJ40_RS04925	COG0588	phosphoglycerate mutase activity
GFJ40_RS04935	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GFJ40_RS04960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GFJ40_RS04965	COG0284	orotidine-5'-phosphate decarboxylase activity
GFJ40_RS04970	COG0543	2 iron, 2 sulfur cluster binding
GFJ40_RS04975	COG0167	dihydroorotate dehydrogenase activity
GFJ40_RS04995	COG0583	DNA-binding transcription factor activity
GFJ40_RS05010	COG0488	(ABC) transporter
GFJ40_RS05015	COG4221	oxidoreductase activity
GFJ40_RS05045	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GFJ40_RS05070	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFJ40_RS05085	COG0436	Aminotransferase
GFJ40_RS05100	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GFJ40_RS05200	COG0045	succinate-CoA ligase (ADP-forming) activity
GFJ40_RS05220	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GFJ40_RS05225	COG1187	pseudouridine synthase activity
GFJ40_RS05290	COG1716	ATPase activity
GFJ40_RS05310	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GFJ40_RS05325	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GFJ40_RS05340	COG0133	tryptophan synthase activity
GFJ40_RS05345	COG2135	peptidase activity
GFJ40_RS05355	COG0833	amino acid
GFJ40_RS05410	COG0745	RESPONSE REGULATOR receiver
GFJ40_RS05425	COG4181	ATPase activity
GFJ40_RS05450	COG0833	amino acid
GFJ40_RS05460	COG3189	MarR family transcriptional regulator
GFJ40_RS05495	COG0693	protein deglycase activity
GFJ40_RS05505	COG0575	Belongs to the CDS family
GFJ40_RS05545	COG0516	GMP reductase activity
GFJ40_RS05575	COG3550	peptidyl-serine autophosphorylation
GFJ40_RS05615	COG4585	Histidine kinase
GFJ40_RS05620	COG2197	response regulator
GFJ40_RS05640	COG0456	acetyltransferase
GFJ40_RS05650	COG0802	atpase or kinase
GFJ40_RS05675	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFJ40_RS05680	COG0598	Magnesium transport protein CorA
GFJ40_RS05685	COG0406	alpha-ribazole phosphatase activity
GFJ40_RS05745	COG0395	ABC-type sugar transport system, permease component
GFJ40_RS05750	COG1175	transmembrane transport
GFJ40_RS05810	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GFJ40_RS05835	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GFJ40_RS05850	COG1201	RNA secondary structure unwinding
GFJ40_RS05855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFJ40_RS05865	COG0187	DNA topoisomerase II activity
GFJ40_RS05870	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GFJ40_RS05880	COG0142	geranyltranstransferase activity
GFJ40_RS05900	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GFJ40_RS05910	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GFJ40_RS05935	COG1396	sequence-specific DNA binding
GFJ40_RS05940	COG1058	Belongs to the CinA family
GFJ40_RS05940	COG1546	Belongs to the CinA family
GFJ40_RS05970	COG2357	RelA SpoT domain protein
GFJ40_RS05995	COG2197	response regulator
GFJ40_RS06010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFJ40_RS06035	COG0708	Exodeoxyribonuclease III
GFJ40_RS06045	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GFJ40_RS06050	COG0601	transmembrane transport
GFJ40_RS06055	COG4166	transmembrane transport
GFJ40_RS06065	COG1136	(ABC) transporter
GFJ40_RS06065	COG0577	efflux transmembrane transporter activity
GFJ40_RS06070	COG0577	efflux transmembrane transporter activity
GFJ40_RS06080	COG0287	Prephenate dehydrogenase
GFJ40_RS06095	COG1217	gtp-binding protein TYPA
GFJ40_RS06105	COG4591	ABC-type transport system involved in lipoprotein release permease component
GFJ40_RS06105	COG1136	(ABC) transporter
GFJ40_RS06115	COG0477	Major facilitator Superfamily
GFJ40_RS06120	COG1104	cysteine desulfurase activity
GFJ40_RS06130	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GFJ40_RS06135	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GFJ40_RS06145	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GFJ40_RS06165	COG1929	Belongs to the glycerate kinase type-1 family
GFJ40_RS06180	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GFJ40_RS06200	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GFJ40_RS06210	COG2017	converts alpha-aldose to the beta-anomer
GFJ40_RS06215	COG2017	converts alpha-aldose to the beta-anomer
GFJ40_RS06225	COG1595	DNA-templated transcription, initiation
GFJ40_RS06245	COG1196	nuclear chromosome segregation
GFJ40_RS06250	COG0285	dihydrofolate synthase activity
GFJ40_RS06255	COG0006	proline dipeptidase activity
GFJ40_RS06275	COG1940	carbohydrate kinase activity
GFJ40_RS06280	COG1940	carbohydrate kinase activity
GFJ40_RS06295	COG0738	Major facilitator superfamily
GFJ40_RS06340	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GFJ40_RS06350	COG0768	penicillin binding
GFJ40_RS06375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFJ40_RS06405	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GFJ40_RS06415	COG1643	Atp-dependent helicase
GFJ40_RS06420	COG2814	Major facilitator Superfamily
GFJ40_RS06470	COG0656	L-ascorbic acid biosynthetic process
GFJ40_RS06480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFJ40_RS06515	COG4716	Myosin-crossreactive antigen
GFJ40_RS06530	COG0587	DNA-directed DNA polymerase activity
GFJ40_RS06565	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GFJ40_RS06590	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFJ40_RS06595	COG0351	phosphomethylpyrimidine kinase
GFJ40_RS06595	COG0352	thiamine-phosphate diphosphorylase activity
GFJ40_RS06605	COG2271	Major facilitator Superfamily
GFJ40_RS06615	COG2197	response regulator
GFJ40_RS06685	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFJ40_RS06690	COG2814	Major facilitator Superfamily
GFJ40_RS06695	COG0745	RESPONSE REGULATOR receiver
GFJ40_RS06705	COG4581	dead DEAH box helicase
GFJ40_RS06710	COG2326	polyphosphate kinase activity
GFJ40_RS06715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GFJ40_RS06720	COG1279	arginine transmembrane transporter activity
GFJ40_RS06730	COG0765	amino acid transport
GFJ40_RS06735	COG0765	amino acid transport
GFJ40_RS06740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GFJ40_RS06745	COG1126	abc transporter atp-binding protein
GFJ40_RS06765	COG1196	nuclear chromosome segregation
GFJ40_RS06780	COG0477	Major facilitator Superfamily
GFJ40_RS06795	COG0402	S-adenosylhomocysteine deaminase activity
GFJ40_RS06805	COG0589	response to stress
GFJ40_RS06815	COG1278	Cold shock
GFJ40_RS06820	COG2205	protein histidine kinase activity
GFJ40_RS06825	COG0745	RESPONSE REGULATOR receiver
GFJ40_RS06845	COG1278	Cold shock
GFJ40_RS06860	COG0714	Associated with various cellular activities
GFJ40_RS06900	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GFJ40_RS06930	COG4122	O-methyltransferase activity
GFJ40_RS06935	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GFJ40_RS06945	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFJ40_RS06950	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFJ40_RS06950	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFJ40_RS06950	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
GFJ40_RS06965	COG1011	Hydrolase
GFJ40_RS06975	COG0586	Pfam SNARE associated Golgi protein
GFJ40_RS06980	COG0560	Phosphoserine phosphatase
GFJ40_RS06985	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GFJ40_RS07040	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
GFJ40_RS07045	COG1518	maintenance of DNA repeat elements
GFJ40_RS07085	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFJ40_RS07090	COG1869	D-ribose catabolic process
GFJ40_RS07100	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFJ40_RS07105	COG1129	ABC transporter
GFJ40_RS07135	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFJ40_RS07140	COG1979	alcohol dehydrogenase
GFJ40_RS07145	COG0546	phosphoglycolate phosphatase activity
GFJ40_RS07155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GFJ40_RS07160	COG0135	phosphoribosylanthranilate isomerase activity
GFJ40_RS07165	COG1122	ATPase activity
GFJ40_RS07190	COG1132	(ABC) transporter
GFJ40_RS07195	COG1132	(ABC) transporter
GFJ40_RS07270	COG1309	transcriptional regulator
GFJ40_RS07285	COG0602	queuosine metabolic process
GFJ40_RS07290	COG1328	CTP reductase activity
GFJ40_RS07290	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GFJ40_RS07295	COG1570	exodeoxyribonuclease VII activity
GFJ40_RS07300	COG1722	exodeoxyribonuclease VII activity
GFJ40_RS07305	COG2249	NAD(P)H dehydrogenase (quinone) activity
GFJ40_RS07310	COG1022	Amp-dependent synthetase and ligase
GFJ40_RS07315	COG1970	mechanosensitive ion channel activity
GFJ40_RS07335	COG0248	Ppx GppA phosphatase
GFJ40_RS07340	COG0436	Aminotransferase
GFJ40_RS07410	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GFJ40_RS07425	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GFJ40_RS07430	COG0009	L-threonylcarbamoyladenylate synthase
GFJ40_RS07480	COG2814	Major facilitator Superfamily
GFJ40_RS07490	COG0242	peptide deformylase activity
GFJ40_RS07510	COG1940	carbohydrate kinase activity
GFJ40_RS07530	COG1946	Acyl-CoA thioesterase
GFJ40_RS07540	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GFJ40_RS07555	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GFJ40_RS07560	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GFJ40_RS07585	COG1215	transferase activity, transferring glycosyl groups
GFJ40_RS07595	COG0463	Glycosyl transferase, family 2
GFJ40_RS07600	COG1454	alcohol dehydrogenase
GFJ40_RS07605	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GFJ40_RS07645	COG3250	beta-galactosidase activity
GFJ40_RS07655	COG1609	Transcriptional regulator
GFJ40_RS07690	COG0577	efflux transmembrane transporter activity
GFJ40_RS07710	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GFJ40_RS07730	COG0589	response to stress
GFJ40_RS07735	COG0791	NLP P60 protein
GFJ40_RS07735	COG3103	Sh3 type 3 domain protein
GFJ40_RS07735	COG1388	LysM domain
GFJ40_RS07745	COG3942	CHAP domain
GFJ40_RS07745	COG1705	Flagellar rod assembly protein muramidase FlgJ
GFJ40_RS07760	COG5002	protein histidine kinase activity
GFJ40_RS07775	COG1575	Belongs to the MenA family. Type 1 subfamily
GFJ40_RS07780	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GFJ40_RS07790	COG0395	ABC-type sugar transport system, permease component
GFJ40_RS07795	COG2814	Major facilitator Superfamily
GFJ40_RS07830	COG2197	response regulator
GFJ40_RS07850	COG0395	ABC-type sugar transport system, permease component
GFJ40_RS07855	COG1175	transmembrane transport
GFJ40_RS07875	COG1597	lipid kinase activity
GFJ40_RS07875	COG1803	Methylglyoxal synthase
GFJ40_RS07905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GFJ40_RS07910	COG0328	RNA-DNA hybrid ribonuclease activity
GFJ40_RS07935	COG0196	riboflavin kinase activity
GFJ40_RS07980	COG2308	Evidence 4 Homologs of previously reported genes of
GFJ40_RS08085	COG0255	Belongs to the universal ribosomal protein uL29 family
GFJ40_RS08135	COG3527	Alpha-acetolactate decarboxylase
GFJ40_RS08145	COG1012	belongs to the aldehyde dehydrogenase family
GFJ40_RS08145	COG1454	alcohol dehydrogenase
GFJ40_RS08155	COG1063	alcohol dehydrogenase
GFJ40_RS08210	COG1739	Uncharacterized protein family UPF0029
GFJ40_RS08215	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GFJ40_RS08225	COG2723	6-phospho-beta-galactosidase activity
GFJ40_RS08235	COG1175	transmembrane transport
GFJ40_RS08245	COG1609	Transcriptional regulator
GFJ40_RS08260	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GFJ40_RS08275	COG0531	amino acid
GFJ40_RS08280	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GFJ40_RS08320	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GFJ40_RS08365	COG2252	PERMEase
GFJ40_RS08390	COG0745	RESPONSE REGULATOR receiver
GFJ40_RS08395	COG5002	protein histidine kinase activity
GFJ40_RS08400	COG0477	Major facilitator Superfamily
GFJ40_RS08410	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFJ40_RS08415	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GFJ40_RS08425	COG3250	beta-galactosidase activity
GFJ40_RS08430	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GFJ40_RS08445	COG0395	ABC-type sugar transport system, permease component
GFJ40_RS08450	COG1175	transmembrane transport
GFJ40_RS08455	COG1653	transport
GFJ40_RS08470	COG3579	cysteine-type endopeptidase activity
GFJ40_RS08485	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GFJ40_RS08500	COG0826	peptidase U32
GFJ40_RS08510	COG0742	ribosomal rna small subunit methyltransferase
GFJ40_RS08525	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GFJ40_RS08525	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GFJ40_RS08530	COG2270	Major facilitator Superfamily
GFJ40_RS08610	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GFJ40_RS08615	COG4770	biotin carboxylase activity
GFJ40_RS08620	COG1268	BioY protein
GFJ40_RS08660	COG0250	Participates in transcription elongation, termination and antitermination
GFJ40_RS08665	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GFJ40_RS08675	COG0436	Aminotransferase
GFJ40_RS08705	COG1530	ribonuclease E activity
GFJ40_RS08710	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GFJ40_RS08720	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GFJ40_RS08740	COG4948	Mandelate Racemase Muconate Lactonizing
GFJ40_RS08745	COG1609	Transcriptional regulator
GFJ40_RS08775	COG0083	homoserine kinase activity
GFJ40_RS08780	COG0460	homoserine dehydrogenase
GFJ40_RS08785	COG1263	PTS System
GFJ40_RS08785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFJ40_RS08785	COG2190	(PTS) system
GFJ40_RS08790	COG1263	PTS System
GFJ40_RS08790	COG2190	(PTS) system
GFJ40_RS08790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFJ40_RS08795	COG0019	diaminopimelate decarboxylase activity
GFJ40_RS08805	COG1309	transcriptional regulator
GFJ40_RS08815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GFJ40_RS08820	COG0446	pyridine nucleotide-disulphide oxidoreductase
GFJ40_RS08830	COG0765	amino acid transport
GFJ40_RS08845	COG1126	abc transporter atp-binding protein
GFJ40_RS08850	COG0167	dihydroorotate dehydrogenase activity
GFJ40_RS08890	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GFJ40_RS08895	COG0406	alpha-ribazole phosphatase activity
GFJ40_RS08895	COG0494	nUDIX hydrolase
GFJ40_RS08925	COG0584	glycerophosphoryl diester phosphodiesterase
GFJ40_RS08945	COG0179	Fumarylacetoacetate (FAA) hydrolase
GFJ40_RS08970	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFJ40_RS08975	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFJ40_RS08980	COG1129	ABC transporter
GFJ40_RS08990	COG1070	Carbohydrate kinase
GFJ40_RS09010	COG1442	glycosyl transferase family 8
GFJ40_RS09010	COG1216	Glycosyl transferase, family 2
GFJ40_RS09020	COG1368	sulfuric ester hydrolase activity
GFJ40_RS09025	COG0438	transferase activity, transferring glycosyl groups
GFJ40_RS09025	COG1216	Glycosyl transferase, family 2
GFJ40_RS09050	COG1088	dTDP-glucose 4,6-dehydratase activity
GFJ40_RS09070	COG1316	TRANSCRIPTIONal
GFJ40_RS09075	COG0577	efflux transmembrane transporter activity
GFJ40_RS09080	COG1129	ABC transporter
GFJ40_RS09100	COG0084	hydrolase, TatD family'
GFJ40_RS09105	COG1132	(ABC) transporter
GFJ40_RS09110	COG1132	(ABC) transporter
GFJ40_RS09135	COG4166	transmembrane transport
GFJ40_RS09220	COG1113	amino acid transport
GFJ40_RS09230	COG1136	(ABC) transporter
GFJ40_RS09230	COG0577	efflux transmembrane transporter activity
GFJ40_RS09235	COG1113	amino acid transport
GFJ40_RS09255	COG1609	Transcriptional regulator
GFJ40_RS09265	COG0588	phosphoglycerate mutase activity
GFJ40_RS09325	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GFJ40_RS09330	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GFJ40_RS09335	COG0366	Alpha amylase catalytic
GFJ40_RS09340	COG0395	ABC-type sugar transport system, permease component
GFJ40_RS09345	COG1175	transmembrane transport
GFJ40_RS09365	COG0590	tRNA wobble adenosine to inosine editing
GFJ40_RS09365	COG0037	tRNA processing
GFJ40_RS09370	COG0025	NhaP-type Na H and K H
GFJ40_RS09375	COG0730	response to heat
GFJ40_RS09400	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GFJ40_RS09410	COG2190	(PTS) system
GFJ40_RS09410	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFJ40_RS09410	COG1263	PTS System
GFJ40_RS09415	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
GFJ40_RS09415	COG1263	PTS System
GFJ40_RS09425	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GFJ40_RS09460	COG1609	Transcriptional regulator
GFJ40_RS09465	COG1879	ABC-type sugar transport system periplasmic component
GFJ40_RS09475	COG1172	Belongs to the binding-protein-dependent transport system permease family
GFJ40_RS09485	COG3415	Transposase
GFJ40_RS09485	COG2801	Transposase and inactivated derivatives
GFJ40_RS09495	COG3842	ATPase activity
GFJ40_RS09500	COG2188	Transcriptional regulator
GFJ40_RS09515	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
GFJ40_RS09520	COG1215	transferase activity, transferring glycosyl groups
GFJ40_RS09540	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GFJ40_RS09565	COG1472	Belongs to the glycosyl hydrolase 3 family
GFJ40_RS09580	COG3279	Response regulator of the LytR AlgR family
GFJ40_RS09605	COG3583	domain protein
GFJ40_RS09625	COG0617	tRNA 3'-terminal CCA addition
GFJ40_RS09645	COG0492	ferredoxin-NADP+ reductase activity
GFJ40_RS09655	COG1192	Involved in chromosome partitioning
GFJ40_RS09665	COG1847	R3H domain protein
