locus-tag	class	description
HQQ90_RS00035	COG1484	DNA-dependent DNA replication
HQQ90_RS00055	COG1216	Glycosyl transferase, family 2
HQQ90_RS00065	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HQQ90_RS00070	COG1442	glycosyl transferase family 8
HQQ90_RS00070	COG1216	Glycosyl transferase, family 2
HQQ90_RS00085	COG0438	transferase activity, transferring glycosyl groups
HQQ90_RS00090	COG0438	transferase activity, transferring glycosyl groups
HQQ90_RS00100	COG1215	transferase activity, transferring glycosyl groups
HQQ90_RS00110	COG1216	Glycosyl transferase, family 2
HQQ90_RS00135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HQQ90_RS00150	COG2814	Major facilitator Superfamily
HQQ90_RS00170	COG0656	L-ascorbic acid biosynthetic process
HQQ90_RS00175	COG3867	Arabinogalactan endo-beta-1,4-galactanase
HQQ90_RS00195	COG1653	transport
HQQ90_RS00205	COG4988	ABC transporter
HQQ90_RS00215	COG2814	Major facilitator Superfamily
HQQ90_RS00215	COG0477	Major facilitator Superfamily
HQQ90_RS00230	COG1609	Transcriptional regulator
HQQ90_RS00235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HQQ90_RS00255	COG1116	anion transmembrane transporter activity
HQQ90_RS00305	COG0667	Aldo Keto reductase
HQQ90_RS00345	COG0440	acetolactate synthase activity
HQQ90_RS00355	COG1487	ribonuclease activity
HQQ90_RS00360	COG0488	(ABC) transporter
HQQ90_RS00375	COG0505	Belongs to the CarA family
HQQ90_RS00405	COG1837	Belongs to the UPF0109 family
HQQ90_RS00445	COG1704	LemA family
HQQ90_RS00455	COG1136	(ABC) transporter
HQQ90_RS00505	COG0475	glutathione-regulated potassium exporter activity
HQQ90_RS00505	COG0569	domain protein
HQQ90_RS00520	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HQQ90_RS00540	COG1373	ATPase (AAA superfamily
HQQ90_RS00545	COG0395	ABC-type sugar transport system, permease component
HQQ90_RS00560	COG3119	arylsulfatase activity
HQQ90_RS00565	COG1609	Transcriptional regulator
HQQ90_RS00570	COG0641	radical SAM
HQQ90_RS00575	COG0730	response to heat
HQQ90_RS00585	COG1027	Aspartate ammonia-lyase
HQQ90_RS00600	COG3842	ATPase activity
HQQ90_RS00635	COG0251	oxidation-reduction process
HQQ90_RS00680	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HQQ90_RS00715	COG0356	it plays a direct role in the translocation of protons across the membrane
HQQ90_RS00740	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HQQ90_RS00755	COG0745	RESPONSE REGULATOR receiver
HQQ90_RS00790	COG0395	ABC-type sugar transport system, permease component
HQQ90_RS00800	COG2182	Extracellular solute-binding protein
HQQ90_RS00865	COG1131	(ABC) transporter
HQQ90_RS00885	COG1937	Protein conserved in bacteria
HQQ90_RS00895	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQQ90_RS00905	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
HQQ90_RS00940	COG1131	(ABC) transporter
HQQ90_RS00990	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HQQ90_RS01015	COG3442	glutamine amidotransferase
HQQ90_RS01020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQQ90_RS01025	COG0305	Participates in initiation and elongation during chromosome replication
HQQ90_RS01035	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HQQ90_RS01055	COG1309	transcriptional regulator
HQQ90_RS01060	COG1442	glycosyl transferase family 8
HQQ90_RS01060	COG1216	Glycosyl transferase, family 2
HQQ90_RS01090	COG0363	glucosamine-6-phosphate deaminase activity
HQQ90_RS01095	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HQQ90_RS01125	COG1136	(ABC) transporter
HQQ90_RS01130	COG0577	efflux transmembrane transporter activity
HQQ90_RS01145	COG3470	protein probably involved in high-affinity Fe2 transport
HQQ90_RS01150	COG0672	)-iron permease
HQQ90_RS01230	COG0604	alcohol dehydrogenase
HQQ90_RS01230	COG1028	Short-chain dehydrogenase reductase Sdr
HQQ90_RS01230	COG3321	synthase
HQQ90_RS01235	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
HQQ90_RS01240	COG0477	Major facilitator Superfamily
HQQ90_RS01255	COG2910	NAD(P)H-binding
HQQ90_RS01260	COG1733	regulation of RNA biosynthetic process
HQQ90_RS01265	COG3619	membrane
HQQ90_RS01345	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HQQ90_RS01365	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
HQQ90_RS01375	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HQQ90_RS01375	COG1754	DNA topoisomerase type I activity
HQQ90_RS01405	COG2186	Transcriptional regulator
HQQ90_RS01430	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQQ90_RS01435	COG4608	Belongs to the ABC transporter superfamily
HQQ90_RS01440	COG0444	Belongs to the ABC transporter superfamily
HQQ90_RS01450	COG0747	negative chemotaxis
HQQ90_RS01460	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HQQ90_RS01465	COG1940	carbohydrate kinase activity
HQQ90_RS01485	COG0527	aspartate kinase activity
HQQ90_RS01525	COG1309	transcriptional regulator
HQQ90_RS01570	COG0586	Pfam SNARE associated Golgi protein
HQQ90_RS01575	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQQ90_RS01580	COG1028	Short-chain dehydrogenase reductase Sdr
HQQ90_RS01595	COG0789	Transcriptional regulator
HQQ90_RS01615	COG1523	belongs to the glycosyl hydrolase 13 family
HQQ90_RS01630	COG3833	ABC-type maltose transport systems, permease component
HQQ90_RS01635	COG1175	transmembrane transport
HQQ90_RS01670	COG1609	Transcriptional regulator
HQQ90_RS01675	COG0366	Alpha amylase catalytic
HQQ90_RS01700	COG0477	Major facilitator Superfamily
HQQ90_RS01705	COG1609	Transcriptional regulator
HQQ90_RS01750	COG0191	fructose-bisphosphate aldolase activity
HQQ90_RS01755	COG0697	spore germination
HQQ90_RS01785	COG0343	queuine tRNA-ribosyltransferase activity
HQQ90_RS01805	COG0494	nUDIX hydrolase
HQQ90_RS01835	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HQQ90_RS01840	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
HQQ90_RS01850	COG0697	spore germination
HQQ90_RS01855	COG0071	Belongs to the small heat shock protein (HSP20) family
HQQ90_RS01890	COG0768	penicillin binding
HQQ90_RS01895	COG0515	serine threonine protein kinase
HQQ90_RS01935	COG0058	SHG alpha-glucan phosphorylase activity
HQQ90_RS01955	COG2197	response regulator
HQQ90_RS01965	COG0180	Tryptophanyl-tRNA synthetase
HQQ90_RS01980	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HQQ90_RS01990	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HQQ90_RS02005	COG4251	negative regulation of phosphorylation
HQQ90_RS02005	COG2203	Gaf domain
HQQ90_RS02005	COG5001	Diguanylate cyclase
HQQ90_RS02005	COG3706	GGDEF domain
HQQ90_RS02070	COG1253	flavin adenine dinucleotide binding
HQQ90_RS02075	COG0783	Belongs to the Dps family
HQQ90_RS02085	COG1609	Transcriptional regulator
HQQ90_RS02130	COG1609	Transcriptional regulator
HQQ90_RS02150	COG1609	Transcriptional regulator
HQQ90_RS02170	COG0783	Belongs to the Dps family
HQQ90_RS02200	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HQQ90_RS02210	COG3250	beta-galactosidase activity
HQQ90_RS02220	COG1609	Transcriptional regulator
HQQ90_RS02230	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HQQ90_RS02235	COG0187	DNA topoisomerase II activity
HQQ90_RS02250	COG0592	DNA-directed DNA polymerase activity
HQQ90_RS02280	COG1847	R3H domain protein
HQQ90_RS02290	COG1192	Involved in chromosome partitioning
HQQ90_RS02320	COG0617	tRNA 3'-terminal CCA addition
HQQ90_RS02340	COG3583	domain protein
HQQ90_RS02365	COG3279	Response regulator of the LytR AlgR family
HQQ90_RS02380	COG1472	Belongs to the glycosyl hydrolase 3 family
HQQ90_RS02405	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HQQ90_RS02425	COG1215	transferase activity, transferring glycosyl groups
HQQ90_RS02430	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQQ90_RS02445	COG2188	Transcriptional regulator
HQQ90_RS02450	COG3842	ATPase activity
HQQ90_RS02460	COG3415	Transposase
HQQ90_RS02460	COG2801	Transposase and inactivated derivatives
HQQ90_RS02470	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQQ90_RS02480	COG1879	ABC-type sugar transport system periplasmic component
HQQ90_RS02485	COG1609	Transcriptional regulator
HQQ90_RS02525	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQQ90_RS02535	COG1263	PTS System
HQQ90_RS02535	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQQ90_RS02540	COG2190	(PTS) system
HQQ90_RS02540	COG1263	PTS System
HQQ90_RS02540	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQQ90_RS02550	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HQQ90_RS02575	COG0730	response to heat
HQQ90_RS02580	COG0025	NhaP-type Na H and K H
HQQ90_RS02585	COG0037	tRNA processing
HQQ90_RS02585	COG0590	tRNA wobble adenosine to inosine editing
HQQ90_RS02605	COG1175	transmembrane transport
HQQ90_RS02610	COG0395	ABC-type sugar transport system, permease component
HQQ90_RS02615	COG0366	Alpha amylase catalytic
HQQ90_RS02620	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HQQ90_RS02625	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HQQ90_RS02685	COG0588	phosphoglycerate mutase activity
HQQ90_RS02695	COG1609	Transcriptional regulator
HQQ90_RS02715	COG1113	amino acid transport
HQQ90_RS02720	COG0577	efflux transmembrane transporter activity
HQQ90_RS02720	COG1136	(ABC) transporter
HQQ90_RS02730	COG1113	amino acid transport
HQQ90_RS02740	COG1846	Transcriptional regulator
HQQ90_RS02815	COG4166	transmembrane transport
HQQ90_RS02835	COG1132	(ABC) transporter
HQQ90_RS02840	COG1132	(ABC) transporter
HQQ90_RS02845	COG0084	hydrolase, TatD family'
HQQ90_RS02865	COG1129	ABC transporter
HQQ90_RS02870	COG0577	efflux transmembrane transporter activity
HQQ90_RS02875	COG1316	TRANSCRIPTIONal
HQQ90_RS02895	COG1088	dTDP-glucose 4,6-dehydratase activity
HQQ90_RS02920	COG1216	Glycosyl transferase, family 2
HQQ90_RS02920	COG0438	transferase activity, transferring glycosyl groups
HQQ90_RS02925	COG1368	sulfuric ester hydrolase activity
HQQ90_RS02935	COG1442	glycosyl transferase family 8
HQQ90_RS02935	COG1216	Glycosyl transferase, family 2
HQQ90_RS02950	COG1070	Carbohydrate kinase
HQQ90_RS02960	COG1129	ABC transporter
HQQ90_RS02965	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQQ90_RS02970	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQQ90_RS02995	COG0179	Fumarylacetoacetate (FAA) hydrolase
HQQ90_RS03015	COG0584	glycerophosphoryl diester phosphodiesterase
HQQ90_RS03050	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HQQ90_RS03085	COG0167	dihydroorotate dehydrogenase activity
HQQ90_RS03090	COG1126	abc transporter atp-binding protein
HQQ90_RS03105	COG0765	amino acid transport
HQQ90_RS03115	COG0446	pyridine nucleotide-disulphide oxidoreductase
HQQ90_RS03120	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HQQ90_RS03130	COG1309	transcriptional regulator
HQQ90_RS03140	COG0019	diaminopimelate decarboxylase activity
HQQ90_RS03145	COG1263	PTS System
HQQ90_RS03145	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQQ90_RS03145	COG2190	(PTS) system
HQQ90_RS03150	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HQQ90_RS03150	COG1263	PTS System
HQQ90_RS03150	COG2190	(PTS) system
HQQ90_RS03155	COG0460	homoserine dehydrogenase
HQQ90_RS03160	COG0083	homoserine kinase activity
HQQ90_RS03195	COG1609	Transcriptional regulator
HQQ90_RS03200	COG4948	Mandelate Racemase Muconate Lactonizing
HQQ90_RS03220	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQQ90_RS03230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQQ90_RS03235	COG1530	ribonuclease E activity
HQQ90_RS03265	COG0436	Aminotransferase
HQQ90_RS03275	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HQQ90_RS03280	COG0250	Participates in transcription elongation, termination and antitermination
HQQ90_RS03315	COG1268	BioY protein
HQQ90_RS03320	COG4770	biotin carboxylase activity
HQQ90_RS03325	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HQQ90_RS03405	COG2270	Major facilitator Superfamily
HQQ90_RS03410	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HQQ90_RS03410	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HQQ90_RS03425	COG0742	ribosomal rna small subunit methyltransferase
HQQ90_RS03450	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HQQ90_RS03465	COG3579	cysteine-type endopeptidase activity
HQQ90_RS03480	COG1653	transport
HQQ90_RS03485	COG1175	transmembrane transport
HQQ90_RS03490	COG0395	ABC-type sugar transport system, permease component
HQQ90_RS03505	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HQQ90_RS03510	COG3250	beta-galactosidase activity
HQQ90_RS03520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQQ90_RS03525	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HQQ90_RS03535	COG0477	Major facilitator Superfamily
HQQ90_RS03540	COG5002	protein histidine kinase activity
HQQ90_RS03545	COG0745	RESPONSE REGULATOR receiver
HQQ90_RS03570	COG2252	PERMEase
HQQ90_RS03615	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
HQQ90_RS03655	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HQQ90_RS03660	COG0531	amino acid
HQQ90_RS03675	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQQ90_RS03695	COG1609	Transcriptional regulator
HQQ90_RS03705	COG1175	transmembrane transport
HQQ90_RS03715	COG2723	6-phospho-beta-galactosidase activity
HQQ90_RS03725	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQQ90_RS03730	COG1739	Uncharacterized protein family UPF0029
HQQ90_RS03785	COG1063	alcohol dehydrogenase
HQQ90_RS03795	COG1012	belongs to the aldehyde dehydrogenase family
HQQ90_RS03795	COG1454	alcohol dehydrogenase
HQQ90_RS03805	COG3527	Alpha-acetolactate decarboxylase
HQQ90_RS03855	COG0255	Belongs to the universal ribosomal protein uL29 family
HQQ90_RS03960	COG2308	Evidence 4 Homologs of previously reported genes of
HQQ90_RS04030	COG0328	RNA-DNA hybrid ribonuclease activity
HQQ90_RS04035	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQQ90_RS04065	COG1597	lipid kinase activity
HQQ90_RS04065	COG1803	Methylglyoxal synthase
HQQ90_RS04090	COG0395	ABC-type sugar transport system, permease component
HQQ90_RS04110	COG2197	response regulator
HQQ90_RS04145	COG2814	Major facilitator Superfamily
HQQ90_RS04150	COG0395	ABC-type sugar transport system, permease component
HQQ90_RS04160	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HQQ90_RS04165	COG1575	Belongs to the MenA family. Type 1 subfamily
HQQ90_RS04180	COG5002	protein histidine kinase activity
HQQ90_RS04195	COG1705	Flagellar rod assembly protein muramidase FlgJ
HQQ90_RS04195	COG3942	CHAP domain
HQQ90_RS04205	COG0791	NLP P60 protein
HQQ90_RS04205	COG3103	Sh3 type 3 domain protein
HQQ90_RS04205	COG1388	LysM domain
HQQ90_RS04210	COG0589	response to stress
HQQ90_RS04230	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HQQ90_RS04250	COG0577	efflux transmembrane transporter activity
HQQ90_RS04280	COG1609	Transcriptional regulator
HQQ90_RS04290	COG3250	beta-galactosidase activity
HQQ90_RS04325	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HQQ90_RS04330	COG1454	alcohol dehydrogenase
HQQ90_RS04335	COG0463	Glycosyl transferase, family 2
HQQ90_RS04345	COG1215	transferase activity, transferring glycosyl groups
HQQ90_RS04375	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HQQ90_RS04390	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HQQ90_RS04400	COG1946	Acyl-CoA thioesterase
HQQ90_RS04420	COG1940	carbohydrate kinase activity
HQQ90_RS04440	COG0242	peptide deformylase activity
HQQ90_RS04450	COG2814	Major facilitator Superfamily
HQQ90_RS04500	COG0009	L-threonylcarbamoyladenylate synthase
HQQ90_RS04505	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HQQ90_RS04520	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HQQ90_RS04590	COG0436	Aminotransferase
HQQ90_RS04595	COG0248	Ppx GppA phosphatase
HQQ90_RS04615	COG1970	mechanosensitive ion channel activity
HQQ90_RS04620	COG1022	Amp-dependent synthetase and ligase
HQQ90_RS04625	COG2249	NAD(P)H dehydrogenase (quinone) activity
HQQ90_RS04630	COG1722	exodeoxyribonuclease VII activity
HQQ90_RS04635	COG1570	exodeoxyribonuclease VII activity
HQQ90_RS04640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HQQ90_RS04640	COG1328	CTP reductase activity
HQQ90_RS04645	COG0602	queuosine metabolic process
HQQ90_RS04660	COG1309	transcriptional regulator
HQQ90_RS04730	COG1132	(ABC) transporter
HQQ90_RS04735	COG1132	(ABC) transporter
HQQ90_RS04760	COG1122	ATPase activity
HQQ90_RS04765	COG0135	phosphoribosylanthranilate isomerase activity
HQQ90_RS04770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQQ90_RS04780	COG0546	phosphoglycolate phosphatase activity
HQQ90_RS04785	COG1979	alcohol dehydrogenase
HQQ90_RS04790	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQQ90_RS04815	COG1129	ABC transporter
HQQ90_RS04820	COG1172	Belongs to the binding-protein-dependent transport system permease family
HQQ90_RS04830	COG1869	D-ribose catabolic process
HQQ90_RS04835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQQ90_RS04880	COG1518	maintenance of DNA repeat elements
HQQ90_RS04885	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HQQ90_RS04940	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HQQ90_RS04945	COG0560	Phosphoserine phosphatase
HQQ90_RS04950	COG0586	Pfam SNARE associated Golgi protein
HQQ90_RS04960	COG1011	Hydrolase
HQQ90_RS04975	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQQ90_RS04975	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
HQQ90_RS04975	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQQ90_RS04980	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
HQQ90_RS04990	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HQQ90_RS04995	COG4122	O-methyltransferase activity
HQQ90_RS05025	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HQQ90_RS05070	COG0714	Associated with various cellular activities
HQQ90_RS05085	COG1278	Cold shock
HQQ90_RS05105	COG0745	RESPONSE REGULATOR receiver
HQQ90_RS05110	COG2205	protein histidine kinase activity
HQQ90_RS05115	COG1278	Cold shock
HQQ90_RS05125	COG0589	response to stress
HQQ90_RS05135	COG0402	S-adenosylhomocysteine deaminase activity
HQQ90_RS05150	COG0477	Major facilitator Superfamily
HQQ90_RS05165	COG1196	nuclear chromosome segregation
HQQ90_RS05185	COG1126	abc transporter atp-binding protein
HQQ90_RS05190	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQQ90_RS05195	COG0765	amino acid transport
HQQ90_RS05200	COG0765	amino acid transport
HQQ90_RS05210	COG1279	arginine transmembrane transporter activity
HQQ90_RS05215	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQQ90_RS05220	COG2326	polyphosphate kinase activity
HQQ90_RS05225	COG4581	dead DEAH box helicase
HQQ90_RS05240	COG2814	Major facilitator Superfamily
HQQ90_RS05245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQQ90_RS05315	COG2197	response regulator
HQQ90_RS05325	COG2271	Major facilitator Superfamily
HQQ90_RS05335	COG0351	phosphomethylpyrimidine kinase
HQQ90_RS05335	COG0352	thiamine-phosphate diphosphorylase activity
HQQ90_RS05340	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HQQ90_RS05365	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HQQ90_RS05400	COG0587	DNA-directed DNA polymerase activity
HQQ90_RS05415	COG4716	Myosin-crossreactive antigen
HQQ90_RS05435	COG4948	Mandelate Racemase Muconate Lactonizing
HQQ90_RS05450	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HQQ90_RS05460	COG0656	L-ascorbic acid biosynthetic process
HQQ90_RS05510	COG2814	Major facilitator Superfamily
HQQ90_RS05515	COG1643	Atp-dependent helicase
HQQ90_RS05525	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HQQ90_RS05555	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HQQ90_RS05580	COG0768	penicillin binding
HQQ90_RS05590	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HQQ90_RS05635	COG0738	Major facilitator superfamily
HQQ90_RS05650	COG1940	carbohydrate kinase activity
HQQ90_RS05655	COG1940	carbohydrate kinase activity
HQQ90_RS05675	COG0006	proline dipeptidase activity
HQQ90_RS05680	COG0285	dihydrofolate synthase activity
HQQ90_RS05685	COG1196	nuclear chromosome segregation
HQQ90_RS05705	COG1595	DNA-templated transcription, initiation
HQQ90_RS05715	COG2017	converts alpha-aldose to the beta-anomer
HQQ90_RS05720	COG2017	converts alpha-aldose to the beta-anomer
HQQ90_RS05730	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HQQ90_RS05755	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HQQ90_RS05770	COG1929	Belongs to the glycerate kinase type-1 family
HQQ90_RS05790	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HQQ90_RS05800	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HQQ90_RS05805	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HQQ90_RS05815	COG1104	cysteine desulfurase activity
HQQ90_RS05820	COG0477	Major facilitator Superfamily
HQQ90_RS05830	COG4591	ABC-type transport system involved in lipoprotein release permease component
HQQ90_RS05830	COG1136	(ABC) transporter
HQQ90_RS05855	COG0287	Prephenate dehydrogenase
HQQ90_RS05865	COG0577	efflux transmembrane transporter activity
HQQ90_RS05870	COG0577	efflux transmembrane transporter activity
HQQ90_RS05870	COG1136	(ABC) transporter
HQQ90_RS05880	COG4166	transmembrane transport
HQQ90_RS05885	COG0601	transmembrane transport
HQQ90_RS05890	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQQ90_RS05900	COG0708	Exodeoxyribonuclease III
HQQ90_RS05925	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HQQ90_RS05940	COG2197	response regulator
HQQ90_RS05955	COG2357	RelA SpoT domain protein
HQQ90_RS05985	COG1058	Belongs to the CinA family
HQQ90_RS05985	COG1546	Belongs to the CinA family
HQQ90_RS05990	COG1396	sequence-specific DNA binding
HQQ90_RS06015	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HQQ90_RS06025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HQQ90_RS06045	COG0142	geranyltranstransferase activity
HQQ90_RS06055	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HQQ90_RS06060	COG0187	DNA topoisomerase II activity
HQQ90_RS06070	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HQQ90_RS06075	COG1201	RNA secondary structure unwinding
HQQ90_RS06090	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HQQ90_RS06115	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HQQ90_RS06175	COG1175	transmembrane transport
HQQ90_RS06180	COG0395	ABC-type sugar transport system, permease component
HQQ90_RS06245	COG0406	alpha-ribazole phosphatase activity
HQQ90_RS06250	COG0598	Magnesium transport protein CorA
HQQ90_RS06255	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HQQ90_RS06280	COG0802	atpase or kinase
HQQ90_RS06290	COG0456	acetyltransferase
HQQ90_RS06305	COG2197	response regulator
HQQ90_RS06310	COG4585	Histidine kinase
HQQ90_RS06350	COG3550	peptidyl-serine autophosphorylation
HQQ90_RS06380	COG0516	GMP reductase activity
HQQ90_RS06420	COG0575	Belongs to the CDS family
HQQ90_RS06430	COG0693	protein deglycase activity
HQQ90_RS06465	COG3189	MarR family transcriptional regulator
HQQ90_RS06475	COG0833	amino acid
HQQ90_RS06500	COG4181	ATPase activity
HQQ90_RS06515	COG0745	RESPONSE REGULATOR receiver
HQQ90_RS06565	COG0833	amino acid
HQQ90_RS06575	COG2135	peptidase activity
HQQ90_RS06580	COG0133	tryptophan synthase activity
HQQ90_RS06595	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HQQ90_RS06610	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HQQ90_RS06630	COG1716	ATPase activity
HQQ90_RS06695	COG1187	pseudouridine synthase activity
HQQ90_RS06700	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HQQ90_RS06720	COG0045	succinate-CoA ligase (ADP-forming) activity
HQQ90_RS06820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HQQ90_RS06835	COG0436	Aminotransferase
HQQ90_RS06850	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HQQ90_RS06875	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HQQ90_RS06905	COG4221	oxidoreductase activity
HQQ90_RS06910	COG0488	(ABC) transporter
HQQ90_RS06925	COG0583	DNA-binding transcription factor activity
HQQ90_RS06945	COG0167	dihydroorotate dehydrogenase activity
HQQ90_RS06950	COG0543	2 iron, 2 sulfur cluster binding
HQQ90_RS06955	COG0284	orotidine-5'-phosphate decarboxylase activity
HQQ90_RS06960	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HQQ90_RS06980	COG3049	Linear amide C-N hydrolases, choloylglycine hydrolase family
HQQ90_RS06985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HQQ90_RS06995	COG0588	phosphoglycerate mutase activity
HQQ90_RS07010	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
HQQ90_RS07020	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
HQQ90_RS07025	COG1073	alpha beta
HQQ90_RS07085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HQQ90_RS07125	COG1119	ATPase activity
HQQ90_RS07130	COG0297	glycogen (starch) synthase activity
HQQ90_RS07145	COG4166	transmembrane transport
HQQ90_RS07155	COG0070	glutamate synthase
HQQ90_RS07155	COG0069	glutamate synthase activity
HQQ90_RS07155	COG0067	glutamate synthase
HQQ90_RS07185	COG2860	membrane
HQQ90_RS07195	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HQQ90_RS07220	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HQQ90_RS07225	COG1022	Amp-dependent synthetase and ligase
HQQ90_RS07250	COG0537	adenosine 5'-monophosphoramidase activity
HQQ90_RS07255	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HQQ90_RS07275	COG2151	metal-sulfur cluster biosynthetic enzyme
HQQ90_RS07285	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HQQ90_RS07290	COG0396	ATPase activity
HQQ90_RS07295	COG0719	Fe-S assembly protein
HQQ90_RS07315	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HQQ90_RS07390	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HQQ90_RS07430	COG3655	Transcriptional regulator
HQQ90_RS07450	COG1335	isochorismatase
HQQ90_RS07455	COG3340	Belongs to the peptidase S51 family
HQQ90_RS07485	COG1131	(ABC) transporter
HQQ90_RS07490	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HQQ90_RS07495	COG4585	Histidine kinase
HQQ90_RS07500	COG2197	response regulator
HQQ90_RS07510	COG0306	phosphate transporter
HQQ90_RS07515	COG0366	Alpha amylase catalytic
HQQ90_RS07520	COG0513	Belongs to the DEAD box helicase family
HQQ90_RS07525	COG2233	PERMEase
HQQ90_RS07565	COG0730	response to heat
HQQ90_RS07570	COG0641	radical SAM
HQQ90_RS07575	COG3119	arylsulfatase activity
HQQ90_RS07580	COG0477	Major facilitator Superfamily
HQQ90_RS07595	COG1846	Transcriptional regulator
HQQ90_RS07595	COG1940	carbohydrate kinase activity
HQQ90_RS07620	COG2814	Major facilitator Superfamily
HQQ90_RS07625	COG1309	transcriptional regulator
HQQ90_RS07670	COG3177	Filamentation induced by cAMP protein fic
HQQ90_RS07680	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HQQ90_RS07700	COG0012	GTP binding
HQQ90_RS07705	COG0765	amino acid transport
HQQ90_RS07710	COG0765	amino acid transport
HQQ90_RS07715	COG1126	abc transporter atp-binding protein
HQQ90_RS07725	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HQQ90_RS07740	COG2197	response regulator
HQQ90_RS07745	COG0577	efflux transmembrane transporter activity
HQQ90_RS07745	COG1136	(ABC) transporter
HQQ90_RS07750	COG1136	(ABC) transporter
HQQ90_RS07755	COG2873	o-acetylhomoserine
HQQ90_RS07780	COG0758	DNA mediated transformation
HQQ90_RS07785	COG1053	succinate dehydrogenase
HQQ90_RS07800	COG1611	Belongs to the LOG family
HQQ90_RS07805	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
HQQ90_RS07810	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HQQ90_RS07870	COG1882	Formate acetyltransferase
HQQ90_RS07885	COG1473	amidohydrolase
HQQ90_RS07890	COG2011	ABC-type metal ion transport system permease component
HQQ90_RS07920	COG0406	alpha-ribazole phosphatase activity
HQQ90_RS07925	COG0799	negative regulation of ribosome biogenesis
HQQ90_RS07960	COG0280	phosphate acetyltransferase
HQQ90_RS07960	COG0857	belongs to the CobB CobQ family
HQQ90_RS07965	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HQQ90_RS07990	COG0519	Catalyzes the synthesis of GMP from XMP
HQQ90_RS08015	COG1051	belongs to the nudix hydrolase family
HQQ90_RS08020	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HQQ90_RS08040	COG0494	nUDIX hydrolase
HQQ90_RS08045	COG0469	pyruvate kinase activity
HQQ90_RS08065	COG0539	negative regulation of cytoplasmic translation
HQQ90_RS08080	COG1121	(ABC) transporter
HQQ90_RS08085	COG1108	ABC-type Mn2 Zn2 transport systems permease components
HQQ90_RS08105	COG0745	RESPONSE REGULATOR receiver
HQQ90_RS08110	COG2205	protein histidine kinase activity
HQQ90_RS08145	COG1316	TRANSCRIPTIONal
HQQ90_RS08170	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HQQ90_RS08180	COG1760	l-serine dehydratase
HQQ90_RS08215	COG0667	Aldo Keto reductase
HQQ90_RS08245	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HQQ90_RS08300	COG0497	DNA recombination
HQQ90_RS08365	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HQQ90_RS08370	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HQQ90_RS08395	COG4115	mRNA cleavage
HQQ90_RS08460	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HQQ90_RS08470	COG1122	ATPase activity
HQQ90_RS08475	COG4721	ABC-type cobalt transport system, permease component
HQQ90_RS08480	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HQQ90_RS08490	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HQQ90_RS08530	COG1122	ATPase activity
HQQ90_RS08545	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HQQ90_RS08625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HQQ90_RS08660	COG0626	cystathionine gamma-synthase activity
HQQ90_RS08680	COG2176	DNA-directed DNA polymerase activity
HQQ90_RS08710	COG1132	(ABC) transporter
HQQ90_RS08715	COG0390	transport system, permease component
HQQ90_RS08750	COG0110	maltose O-acetyltransferase activity
HQQ90_RS08770	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HQQ90_RS08815	COG1063	alcohol dehydrogenase
HQQ90_RS08845	COG0583	DNA-binding transcription factor activity
HQQ90_RS08875	COG0385	Bile acid
HQQ90_RS08895	COG0436	Aminotransferase
HQQ90_RS08910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HQQ90_RS08945	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HQQ90_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
HQQ90_RS08985	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HQQ90_RS08990	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HQQ90_RS08995	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HQQ90_RS09005	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HQQ90_RS09025	COG0701	Predicted permease
HQQ90_RS09050	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HQQ90_RS09070	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HQQ90_RS09075	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HQQ90_RS09080	COG0604	alcohol dehydrogenase
HQQ90_RS09085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HQQ90_RS09090	COG0577	efflux transmembrane transporter activity
HQQ90_RS09090	COG0577	efflux transmembrane transporter activity
HQQ90_RS09100	COG1136	(ABC) transporter
HQQ90_RS09100	COG0577	efflux transmembrane transporter activity
HQQ90_RS09125	COG0366	Alpha amylase catalytic
HQQ90_RS09130	COG1609	Transcriptional regulator
HQQ90_RS09165	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
HQQ90_RS09170	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HQQ90_RS09185	COG0358	DNA primase activity
HQQ90_RS09195	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HQQ90_RS09200	COG0531	amino acid
HQQ90_RS09215	COG0514	ATP-dependent DNA helicase (RecQ)
HQQ90_RS09220	COG0626	cystathionine gamma-synthase activity
HQQ90_RS09230	COG4608	Belongs to the ABC transporter superfamily
HQQ90_RS09240	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HQQ90_RS09245	COG0601	transmembrane transport
HQQ90_RS09265	COG1653	transport
HQQ90_RS09275	COG0395	ABC-type sugar transport system, permease component
HQQ90_RS09280	COG1175	transmembrane transport
HQQ90_RS09290	COG0564	pseudouridine synthase activity
HQQ90_RS09300	COG1126	abc transporter atp-binding protein
HQQ90_RS09325	COG1388	LysM domain
HQQ90_RS09325	COG3942	CHAP domain
HQQ90_RS09330	COG2177	Part of the ABC transporter FtsEX involved in
HQQ90_RS09335	COG2884	Cell division ATP-binding protein ftsE
HQQ90_RS09340	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HQQ90_RS09365	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HQQ90_RS09385	COG0210	DNA helicase
HQQ90_RS09400	COG0714	Associated with various cellular activities
HQQ90_RS09435	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HQQ90_RS09450	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HQQ90_RS09460	COG1349	DNA-binding transcription factor activity
HQQ90_RS09465	COG0167	dihydroorotate dehydrogenase activity
HQQ90_RS09470	COG1902	pentaerythritol trinitrate reductase activity
HQQ90_RS09475	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HQQ90_RS09475	COG4499	WXG100 protein secretion system (Wss), protein YukC
HQQ90_RS09480	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HQQ90_RS09485	COG0095	Lipoate-protein ligase
HQQ90_RS09540	COG0489	protein tyrosine kinase activity
HQQ90_RS09615	COG1484	DNA-dependent DNA replication
HQQ90_RS09635	COG1216	Glycosyl transferase, family 2
HQQ90_RS09645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain