locus-tag	class	description
BBL520_RS00015	COG0592	DNA-directed DNA polymerase activity
BBL520_RS00030	COG0187	DNA topoisomerase II activity
BBL520_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBL520_RS00045	COG1609	Transcriptional regulator
BBL520_RS00055	COG3250	beta-galactosidase activity
BBL520_RS00070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBL520_RS00105	COG0783	Belongs to the Dps family
BBL520_RS00125	COG1609	Transcriptional regulator
BBL520_RS00145	COG1609	Transcriptional regulator
BBL520_RS00190	COG1609	Transcriptional regulator
BBL520_RS00200	COG0783	Belongs to the Dps family
BBL520_RS00205	COG1253	flavin adenine dinucleotide binding
BBL520_RS00270	COG2203	Gaf domain
BBL520_RS00270	COG3706	GGDEF domain
BBL520_RS00270	COG4251	negative regulation of phosphorylation
BBL520_RS00270	COG5001	Diguanylate cyclase
BBL520_RS00285	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BBL520_RS00295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBL520_RS00310	COG0180	Tryptophanyl-tRNA synthetase
BBL520_RS00340	COG0058	SHG alpha-glucan phosphorylase activity
BBL520_RS00380	COG0515	serine threonine protein kinase
BBL520_RS00385	COG0768	penicillin binding
BBL520_RS00420	COG0071	Belongs to the small heat shock protein (HSP20) family
BBL520_RS00425	COG0697	spore germination
BBL520_RS00435	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BBL520_RS00440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BBL520_RS00470	COG0494	nUDIX hydrolase
BBL520_RS00490	COG0343	queuine tRNA-ribosyltransferase activity
BBL520_RS00525	COG0191	fructose-bisphosphate aldolase activity
BBL520_RS00565	COG1609	Transcriptional regulator
BBL520_RS00570	COG0477	Major facilitator Superfamily
BBL520_RS00595	COG0395	ABC-type sugar transport system, permease component
BBL520_RS00620	COG0366	Alpha amylase catalytic
BBL520_RS00625	COG1609	Transcriptional regulator
BBL520_RS00660	COG1175	transmembrane transport
BBL520_RS00665	COG3833	ABC-type maltose transport systems, permease component
BBL520_RS00670	COG1523	belongs to the glycosyl hydrolase 13 family
BBL520_RS00685	COG1609	Transcriptional regulator
BBL520_RS00690	COG1523	belongs to the glycosyl hydrolase 13 family
BBL520_RS00710	COG0789	Transcriptional regulator
BBL520_RS00725	COG1028	Short-chain dehydrogenase reductase Sdr
BBL520_RS00730	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBL520_RS00735	COG0586	Pfam SNARE associated Golgi protein
BBL520_RS00845	COG0527	aspartate kinase activity
BBL520_RS00865	COG1940	carbohydrate kinase activity
BBL520_RS00870	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BBL520_RS00880	COG0747	negative chemotaxis
BBL520_RS00890	COG0444	Belongs to the ABC transporter superfamily
BBL520_RS00895	COG4608	Belongs to the ABC transporter superfamily
BBL520_RS00900	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBL520_RS00925	COG2186	Transcriptional regulator
BBL520_RS00965	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBL520_RS00965	COG1754	DNA topoisomerase type I activity
BBL520_RS00975	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBL520_RS00990	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBL520_RS01075	COG0672	)-iron permease
BBL520_RS01080	COG3470	protein probably involved in high-affinity Fe2 transport
BBL520_RS01090	COG0577	efflux transmembrane transporter activity
BBL520_RS01095	COG0577	efflux transmembrane transporter activity
BBL520_RS01100	COG1136	(ABC) transporter
BBL520_RS01145	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BBL520_RS01150	COG0363	glucosamine-6-phosphate deaminase activity
BBL520_RS01180	COG1216	Glycosyl transferase, family 2
BBL520_RS01180	COG1442	glycosyl transferase family 8
BBL520_RS01185	COG1309	transcriptional regulator
BBL520_RS01205	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BBL520_RS01215	COG0305	Participates in initiation and elongation during chromosome replication
BBL520_RS01220	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBL520_RS01225	COG3442	glutamine amidotransferase
BBL520_RS01250	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBL520_RS01285	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBL520_RS01295	COG1937	Protein conserved in bacteria
BBL520_RS01315	COG1131	(ABC) transporter
BBL520_RS01400	COG0745	RESPONSE REGULATOR receiver
BBL520_RS01415	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BBL520_RS01655	COG3942	CHAP domain
BBL520_RS01655	COG1388	LysM domain
BBL520_RS01675	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BBL520_RS01690	COG0356	it plays a direct role in the translocation of protons across the membrane
BBL520_RS01725	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BBL520_RS01765	COG0251	oxidation-reduction process
BBL520_RS01800	COG3842	ATPase activity
BBL520_RS01815	COG1027	Aspartate ammonia-lyase
BBL520_RS01830	COG0730	response to heat
BBL520_RS01835	COG0641	radical SAM
BBL520_RS01840	COG1609	Transcriptional regulator
BBL520_RS01845	COG3119	arylsulfatase activity
BBL520_RS01865	COG0395	ABC-type sugar transport system, permease component
BBL520_RS01870	COG1373	ATPase (AAA superfamily
BBL520_RS01875	COG3328	transposase activity
BBL520_RS01890	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BBL520_RS01905	COG0569	domain protein
BBL520_RS01905	COG0475	glutathione-regulated potassium exporter activity
BBL520_RS01960	COG1704	LemA family
BBL520_RS01995	COG1837	Belongs to the UPF0109 family
BBL520_RS02030	COG0505	Belongs to the CarA family
BBL520_RS02035	COG0488	(ABC) transporter
BBL520_RS02040	COG1487	ribonuclease activity
BBL520_RS02050	COG0440	acetolactate synthase activity
BBL520_RS02090	COG0667	Aldo Keto reductase
BBL520_RS02140	COG1116	anion transmembrane transporter activity
BBL520_RS02165	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBL520_RS02170	COG1609	Transcriptional regulator
BBL520_RS02185	COG2814	Major facilitator Superfamily
BBL520_RS02185	COG0477	Major facilitator Superfamily
BBL520_RS02195	COG4988	ABC transporter
BBL520_RS02210	COG1653	transport
BBL520_RS02215	COG1175	transmembrane transport
BBL520_RS02230	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BBL520_RS02240	COG0656	L-ascorbic acid biosynthetic process
BBL520_RS02260	COG2814	Major facilitator Superfamily
BBL520_RS02275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBL520_RS02295	COG1216	Glycosyl transferase, family 2
BBL520_RS02295	COG1442	glycosyl transferase family 8
BBL520_RS02305	COG1215	transferase activity, transferring glycosyl groups
BBL520_RS02340	COG1216	Glycosyl transferase, family 2
BBL520_RS02375	COG1442	glycosyl transferase family 8
BBL520_RS02375	COG1216	Glycosyl transferase, family 2
BBL520_RS02390	COG0438	transferase activity, transferring glycosyl groups
BBL520_RS02400	COG1215	transferase activity, transferring glycosyl groups
BBL520_RS02405	COG0215	cysteine-tRNA ligase activity
BBL520_RS02410	COG2826	transposase and inactivated derivatives, IS30 family
BBL520_RS02435	COG2801	Transposase and inactivated derivatives
BBL520_RS02480	COG0489	protein tyrosine kinase activity
BBL520_RS02540	COG0095	Lipoate-protein ligase
BBL520_RS02545	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBL520_RS02550	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBL520_RS02550	COG4499	WXG100 protein secretion system (Wss), protein YukC
BBL520_RS02555	COG1902	pentaerythritol trinitrate reductase activity
BBL520_RS02560	COG0167	dihydroorotate dehydrogenase activity
BBL520_RS02565	COG1349	DNA-binding transcription factor activity
BBL520_RS02575	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BBL520_RS02600	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BBL520_RS02635	COG0714	Associated with various cellular activities
BBL520_RS02650	COG0210	DNA helicase
BBL520_RS02670	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBL520_RS02695	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBL520_RS02700	COG2884	Cell division ATP-binding protein ftsE
BBL520_RS02705	COG2177	Part of the ABC transporter FtsEX involved in
BBL520_RS02710	COG1388	LysM domain
BBL520_RS02710	COG3942	CHAP domain
BBL520_RS02735	COG1126	abc transporter atp-binding protein
BBL520_RS02745	COG0564	pseudouridine synthase activity
BBL520_RS02750	COG1609	Transcriptional regulator
BBL520_RS02760	COG1175	transmembrane transport
BBL520_RS02765	COG0395	ABC-type sugar transport system, permease component
BBL520_RS02775	COG1653	transport
BBL520_RS02795	COG0601	transmembrane transport
BBL520_RS02800	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBL520_RS02810	COG4608	Belongs to the ABC transporter superfamily
BBL520_RS02820	COG0626	cystathionine gamma-synthase activity
BBL520_RS02825	COG0514	ATP-dependent DNA helicase (RecQ)
BBL520_RS02840	COG0531	amino acid
BBL520_RS02845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBL520_RS02855	COG0358	DNA primase activity
BBL520_RS02880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBL520_RS02885	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBL520_RS02920	COG1609	Transcriptional regulator
BBL520_RS02925	COG0366	Alpha amylase catalytic
BBL520_RS02955	COG1136	(ABC) transporter
BBL520_RS02955	COG0577	efflux transmembrane transporter activity
BBL520_RS02965	COG0577	efflux transmembrane transporter activity
BBL520_RS02965	COG0577	efflux transmembrane transporter activity
BBL520_RS02970	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBL520_RS02975	COG0604	alcohol dehydrogenase
BBL520_RS02980	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBL520_RS02985	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBL520_RS03005	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BBL520_RS03030	COG0701	Predicted permease
BBL520_RS03060	COG1012	belongs to the aldehyde dehydrogenase family
BBL520_RS03080	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBL520_RS03140	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBL520_RS03155	COG0436	Aminotransferase
BBL520_RS03175	COG0385	Bile acid
BBL520_RS03205	COG0583	DNA-binding transcription factor activity
BBL520_RS03215	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBL520_RS03235	COG1063	alcohol dehydrogenase
BBL520_RS03255	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBL520_RS03305	COG1175	transmembrane transport
BBL520_RS03335	COG2199	diguanylate cyclase activity
BBL520_RS03340	COG0390	transport system, permease component
BBL520_RS03345	COG1132	(ABC) transporter
BBL520_RS03370	COG0284	orotidine-5'-phosphate decarboxylase activity
BBL520_RS03380	COG2176	DNA-directed DNA polymerase activity
BBL520_RS03400	COG0626	cystathionine gamma-synthase activity
BBL520_RS03445	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBL520_RS03535	COG0436	Aminotransferase
BBL520_RS03540	COG1122	ATPase activity
BBL520_RS03580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBL520_RS03590	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBL520_RS03595	COG4721	ABC-type cobalt transport system, permease component
BBL520_RS03600	COG1122	ATPase activity
BBL520_RS03610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBL520_RS03680	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BBL520_RS03685	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBL520_RS03725	COG0569	domain protein
BBL520_RS03740	COG0497	DNA recombination
BBL520_RS03745	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBL520_RS03780	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBL520_RS03805	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBL520_RS03815	COG0701	Predicted permease
BBL520_RS03830	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBL520_RS03830	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBL520_RS03845	COG0667	Aldo Keto reductase
BBL520_RS03880	COG1760	l-serine dehydratase
BBL520_RS03890	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBL520_RS03915	COG1316	TRANSCRIPTIONal
BBL520_RS03950	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BBL520_RS03955	COG2205	protein histidine kinase activity
BBL520_RS03960	COG0745	RESPONSE REGULATOR receiver
BBL520_RS03980	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBL520_RS03985	COG1121	(ABC) transporter
BBL520_RS04000	COG0539	negative regulation of cytoplasmic translation
BBL520_RS04020	COG0469	pyruvate kinase activity
BBL520_RS04025	COG0494	nUDIX hydrolase
BBL520_RS04045	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBL520_RS04050	COG1051	belongs to the nudix hydrolase family
BBL520_RS04075	COG0519	Catalyzes the synthesis of GMP from XMP
BBL520_RS04105	COG2823	Periplasmic or secreted lipoprotein
BBL520_RS04105	COG1652	LysM domain
BBL520_RS04140	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBL520_RS04145	COG0857	belongs to the CobB CobQ family
BBL520_RS04145	COG0280	phosphate acetyltransferase
BBL520_RS04185	COG0799	negative regulation of ribosome biogenesis
BBL520_RS04190	COG0406	alpha-ribazole phosphatase activity
BBL520_RS04220	COG2011	ABC-type metal ion transport system permease component
BBL520_RS04225	COG1473	amidohydrolase
BBL520_RS04240	COG1882	Formate acetyltransferase
BBL520_RS04300	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBL520_RS04305	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BBL520_RS04310	COG1611	Belongs to the LOG family
BBL520_RS04325	COG1053	succinate dehydrogenase
BBL520_RS04330	COG0758	DNA mediated transformation
BBL520_RS04345	COG2826	transposase and inactivated derivatives, IS30 family
BBL520_RS04355	COG2873	o-acetylhomoserine
BBL520_RS04360	COG1136	(ABC) transporter
BBL520_RS04365	COG0577	efflux transmembrane transporter activity
BBL520_RS04365	COG1136	(ABC) transporter
BBL520_RS04370	COG2197	response regulator
BBL520_RS04385	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBL520_RS04395	COG1126	abc transporter atp-binding protein
BBL520_RS04400	COG0765	amino acid transport
BBL520_RS04405	COG0765	amino acid transport
BBL520_RS04410	COG0012	GTP binding
BBL520_RS04415	COG3177	Filamentation induced by cAMP protein fic
BBL520_RS04465	COG1309	transcriptional regulator
BBL520_RS04480	COG2814	Major facilitator Superfamily
BBL520_RS04525	COG2233	PERMEase
BBL520_RS04530	COG0513	Belongs to the DEAD box helicase family
BBL520_RS04535	COG0366	Alpha amylase catalytic
BBL520_RS04540	COG0306	phosphate transporter
BBL520_RS04550	COG2197	response regulator
BBL520_RS04555	COG4585	Histidine kinase
BBL520_RS04560	COG1131	(ABC) transporter
BBL520_RS04590	COG3340	Belongs to the peptidase S51 family
BBL520_RS04595	COG1335	isochorismatase
BBL520_RS04610	COG3655	Transcriptional regulator
BBL520_RS04645	COG1136	(ABC) transporter
BBL520_RS04655	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBL520_RS04735	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBL520_RS04760	COG0719	Fe-S assembly protein
BBL520_RS04765	COG0396	ATPase activity
BBL520_RS04770	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBL520_RS04780	COG2151	metal-sulfur cluster biosynthetic enzyme
BBL520_RS04800	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBL520_RS04805	COG0537	adenosine 5'-monophosphoramidase activity
BBL520_RS04830	COG1022	Amp-dependent synthetase and ligase
BBL520_RS04835	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BBL520_RS04860	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBL520_RS04870	COG2860	membrane
BBL520_RS04905	COG0067	glutamate synthase
BBL520_RS04905	COG0069	glutamate synthase activity
BBL520_RS04905	COG0070	glutamate synthase
BBL520_RS04920	COG4166	transmembrane transport
BBL520_RS04935	COG0297	glycogen (starch) synthase activity
BBL520_RS04940	COG1119	ATPase activity
BBL520_RS04945	COG0561	phosphatase activity
BBL520_RS04975	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BBL520_RS05070	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BBL520_RS05080	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BBL520_RS05100	COG0588	phosphoglycerate mutase activity
BBL520_RS05110	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBL520_RS05135	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBL520_RS05140	COG0284	orotidine-5'-phosphate decarboxylase activity
BBL520_RS05145	COG0543	2 iron, 2 sulfur cluster binding
BBL520_RS05150	COG0167	dihydroorotate dehydrogenase activity
BBL520_RS05170	COG0583	DNA-binding transcription factor activity
BBL520_RS05185	COG0488	(ABC) transporter
BBL520_RS05190	COG4221	oxidoreductase activity
BBL520_RS05195	COG1129	ABC transporter
BBL520_RS05225	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBL520_RS05250	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBL520_RS05265	COG0436	Aminotransferase
BBL520_RS05280	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBL520_RS05475	COG1475	DNA binding
BBL520_RS05555	COG4974	Belongs to the 'phage' integrase family
BBL520_RS05640	COG0045	succinate-CoA ligase (ADP-forming) activity
BBL520_RS05665	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBL520_RS05670	COG1187	pseudouridine synthase activity
BBL520_RS05685	COG0561	phosphatase activity
BBL520_RS05735	COG1716	ATPase activity
BBL520_RS05770	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBL520_RS05785	COG0133	tryptophan synthase activity
BBL520_RS05790	COG2135	peptidase activity
BBL520_RS05800	COG0833	amino acid
BBL520_RS05875	COG0745	RESPONSE REGULATOR receiver
BBL520_RS05890	COG4181	ATPase activity
BBL520_RS05935	COG1131	(ABC) transporter
BBL520_RS05965	COG1131	(ABC) transporter
BBL520_RS05975	COG2197	response regulator
BBL520_RS05980	COG4585	Histidine kinase
BBL520_RS05990	COG0577	efflux transmembrane transporter activity
BBL520_RS05990	COG1136	(ABC) transporter
BBL520_RS06035	COG0833	amino acid
BBL520_RS06045	COG3189	MarR family transcriptional regulator
BBL520_RS06080	COG0693	protein deglycase activity
BBL520_RS06090	COG0575	Belongs to the CDS family
BBL520_RS06130	COG0516	GMP reductase activity
BBL520_RS06205	COG3942	CHAP domain
BBL520_RS06225	COG0551	DNA topoisomerase type I activity
BBL520_RS06225	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBL520_RS06245	COG3550	peptidyl-serine autophosphorylation
BBL520_RS06400	COG1192	Involved in chromosome partitioning
BBL520_RS06460	COG0456	acetyltransferase
BBL520_RS06470	COG0802	atpase or kinase
BBL520_RS06495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBL520_RS06500	COG0598	Magnesium transport protein CorA
BBL520_RS06505	COG0406	alpha-ribazole phosphatase activity
BBL520_RS06560	COG0395	ABC-type sugar transport system, permease component
BBL520_RS06565	COG1175	transmembrane transport
BBL520_RS06570	COG1653	transport
BBL520_RS06620	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBL520_RS06645	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBL520_RS06660	COG1201	RNA secondary structure unwinding
BBL520_RS06665	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBL520_RS06675	COG0187	DNA topoisomerase II activity
BBL520_RS06680	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBL520_RS06690	COG0142	geranyltranstransferase activity
BBL520_RS06710	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBL520_RS06720	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBL520_RS06745	COG1396	sequence-specific DNA binding
BBL520_RS06750	COG1546	Belongs to the CinA family
BBL520_RS06750	COG1058	Belongs to the CinA family
BBL520_RS06780	COG2357	RelA SpoT domain protein
BBL520_RS06810	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBL520_RS06835	COG0708	Exodeoxyribonuclease III
BBL520_RS06845	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBL520_RS06850	COG0601	transmembrane transport
BBL520_RS06855	COG4166	transmembrane transport
BBL520_RS06865	COG0577	efflux transmembrane transporter activity
BBL520_RS06865	COG1136	(ABC) transporter
BBL520_RS06870	COG0577	efflux transmembrane transporter activity
BBL520_RS06880	COG0287	Prephenate dehydrogenase
BBL520_RS06895	COG1217	gtp-binding protein TYPA
BBL520_RS06905	COG1136	(ABC) transporter
BBL520_RS06905	COG0577	efflux transmembrane transporter activity
BBL520_RS06915	COG0477	Major facilitator Superfamily
BBL520_RS06930	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BBL520_RS06935	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BBL520_RS06945	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBL520_RS06950	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBL520_RS06965	COG1929	Belongs to the glycerate kinase type-1 family
BBL520_RS06980	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBL520_RS07000	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBL520_RS07010	COG2017	converts alpha-aldose to the beta-anomer
BBL520_RS07015	COG2017	converts alpha-aldose to the beta-anomer
BBL520_RS07050	COG1595	DNA-templated transcription, initiation
BBL520_RS07070	COG1196	nuclear chromosome segregation
BBL520_RS07075	COG0285	dihydrofolate synthase activity
BBL520_RS07080	COG0006	proline dipeptidase activity
BBL520_RS07100	COG1940	carbohydrate kinase activity
BBL520_RS07105	COG1940	carbohydrate kinase activity
BBL520_RS07165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBL520_RS07175	COG0768	penicillin binding
BBL520_RS07200	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBL520_RS07230	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBL520_RS07240	COG1643	Atp-dependent helicase
BBL520_RS07245	COG2814	Major facilitator Superfamily
BBL520_RS07295	COG0656	L-ascorbic acid biosynthetic process
BBL520_RS07305	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBL520_RS07320	COG4948	Mandelate Racemase Muconate Lactonizing
BBL520_RS07345	COG4716	Myosin-crossreactive antigen
BBL520_RS07360	COG0587	DNA-directed DNA polymerase activity
BBL520_RS07400	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBL520_RS07425	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBL520_RS07430	COG0352	thiamine-phosphate diphosphorylase activity
BBL520_RS07430	COG0351	phosphomethylpyrimidine kinase
BBL520_RS07445	COG2271	Major facilitator Superfamily
BBL520_RS07455	COG2197	response regulator
BBL520_RS07525	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBL520_RS07530	COG2814	Major facilitator Superfamily
BBL520_RS07535	COG0745	RESPONSE REGULATOR receiver
BBL520_RS07545	COG4581	dead DEAH box helicase
BBL520_RS07550	COG2326	polyphosphate kinase activity
BBL520_RS07555	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBL520_RS07560	COG1279	arginine transmembrane transporter activity
BBL520_RS07570	COG0765	amino acid transport
BBL520_RS07575	COG0765	amino acid transport
BBL520_RS07580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBL520_RS07585	COG1126	abc transporter atp-binding protein
BBL520_RS07605	COG1196	nuclear chromosome segregation
BBL520_RS07625	COG0477	Major facilitator Superfamily
BBL520_RS07640	COG0589	response to stress
BBL520_RS07650	COG1278	Cold shock
BBL520_RS07655	COG2205	protein histidine kinase activity
BBL520_RS07660	COG0745	RESPONSE REGULATOR receiver
BBL520_RS07680	COG1278	Cold shock
BBL520_RS07695	COG0714	Associated with various cellular activities
BBL520_RS07740	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBL520_RS07770	COG4122	O-methyltransferase activity
BBL520_RS07775	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBL520_RS07780	COG1011	Hydrolase
BBL520_RS07790	COG0586	Pfam SNARE associated Golgi protein
BBL520_RS07795	COG0560	Phosphoserine phosphatase
BBL520_RS07800	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBL520_RS07835	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BBL520_RS07890	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBL520_RS07910	COG1132	(ABC) transporter
BBL520_RS07915	COG1132	(ABC) transporter
BBL520_RS07985	COG1309	transcriptional regulator
BBL520_RS08000	COG0602	queuosine metabolic process
BBL520_RS08005	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBL520_RS08005	COG1328	CTP reductase activity
BBL520_RS08010	COG1570	exodeoxyribonuclease VII activity
BBL520_RS08015	COG1722	exodeoxyribonuclease VII activity
BBL520_RS08020	COG2249	NAD(P)H dehydrogenase (quinone) activity
BBL520_RS08025	COG1022	Amp-dependent synthetase and ligase
BBL520_RS08030	COG1970	mechanosensitive ion channel activity
BBL520_RS08050	COG0248	Ppx GppA phosphatase
BBL520_RS08055	COG0436	Aminotransferase
BBL520_RS08130	COG1355	regulation of microtubule-based process
BBL520_RS08135	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBL520_RS08145	COG1609	Transcriptional regulator
BBL520_RS08175	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BBL520_RS08185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBL520_RS08190	COG0009	L-threonylcarbamoyladenylate synthase
BBL520_RS08215	COG0683	leucine binding
BBL520_RS08245	COG2814	Major facilitator Superfamily
BBL520_RS08255	COG0242	peptide deformylase activity
BBL520_RS08275	COG1940	carbohydrate kinase activity
BBL520_RS08300	COG1946	Acyl-CoA thioesterase
BBL520_RS08310	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBL520_RS08325	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBL520_RS08330	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BBL520_RS08355	COG1215	transferase activity, transferring glycosyl groups
BBL520_RS08365	COG0463	Glycosyl transferase, family 2
BBL520_RS08370	COG1454	alcohol dehydrogenase
BBL520_RS08375	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBL520_RS08420	COG1192	Involved in chromosome partitioning
BBL520_RS08450	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BBL520_RS08465	COG4133	protoheme IX ABC transporter activity
BBL520_RS08490	COG1131	(ABC) transporter
BBL520_RS08500	COG1609	Transcriptional regulator
BBL520_RS08510	COG1136	(ABC) transporter
BBL520_RS08530	COG0745	RESPONSE REGULATOR receiver
BBL520_RS08590	COG1192	Involved in chromosome partitioning
BBL520_RS08600	COG0488	(ABC) transporter
BBL520_RS08625	COG1569	PIN domain
BBL520_RS08650	COG3942	CHAP domain
BBL520_RS08650	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBL520_RS08685	COG3250	beta-galactosidase activity
BBL520_RS08690	COG1609	Transcriptional regulator
BBL520_RS08715	COG0577	efflux transmembrane transporter activity
BBL520_RS08735	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBL520_RS08755	COG0589	response to stress
BBL520_RS08760	COG0791	NLP P60 protein
BBL520_RS08760	COG1388	LysM domain
BBL520_RS08760	COG3103	Sh3 type 3 domain protein
BBL520_RS08770	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBL520_RS08770	COG3942	CHAP domain
BBL520_RS08775	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BBL520_RS08785	COG5002	protein histidine kinase activity
BBL520_RS08800	COG1575	Belongs to the MenA family. Type 1 subfamily
BBL520_RS08805	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBL520_RS08820	COG2814	Major facilitator Superfamily
BBL520_RS08855	COG2197	response regulator
BBL520_RS08875	COG0395	ABC-type sugar transport system, permease component
BBL520_RS08880	COG1175	transmembrane transport
BBL520_RS08900	COG1803	Methylglyoxal synthase
BBL520_RS08900	COG1597	lipid kinase activity
BBL520_RS08930	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBL520_RS08935	COG0328	RNA-DNA hybrid ribonuclease activity
BBL520_RS09005	COG2308	Evidence 4 Homologs of previously reported genes of
BBL520_RS09110	COG0255	Belongs to the universal ribosomal protein uL29 family
BBL520_RS09160	COG3527	Alpha-acetolactate decarboxylase
BBL520_RS09170	COG1454	alcohol dehydrogenase
BBL520_RS09170	COG1012	belongs to the aldehyde dehydrogenase family
BBL520_RS09180	COG1063	alcohol dehydrogenase
BBL520_RS09235	COG1739	Uncharacterized protein family UPF0029
BBL520_RS09240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBL520_RS09260	COG1175	transmembrane transport
BBL520_RS09270	COG1609	Transcriptional regulator
BBL520_RS09285	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBL520_RS09300	COG0531	amino acid
BBL520_RS09305	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBL520_RS09350	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BBL520_RS09400	COG2252	PERMEase
BBL520_RS09425	COG0745	RESPONSE REGULATOR receiver
BBL520_RS09430	COG5002	protein histidine kinase activity
BBL520_RS09445	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBL520_RS09450	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBL520_RS09465	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BBL520_RS09480	COG0826	peptidase U32
BBL520_RS09490	COG0742	ribosomal rna small subunit methyltransferase
BBL520_RS09505	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BBL520_RS09505	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BBL520_RS09510	COG2270	Major facilitator Superfamily
BBL520_RS09605	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBL520_RS09610	COG4770	biotin carboxylase activity
BBL520_RS09615	COG1268	BioY protein
BBL520_RS09650	COG0250	Participates in transcription elongation, termination and antitermination
BBL520_RS09655	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBL520_RS09665	COG0436	Aminotransferase
BBL520_RS09695	COG1530	ribonuclease E activity
BBL520_RS09700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBL520_RS09710	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBL520_RS09735	COG4948	Mandelate Racemase Muconate Lactonizing
BBL520_RS09740	COG1609	Transcriptional regulator
BBL520_RS09770	COG0083	homoserine kinase activity
BBL520_RS09775	COG0460	homoserine dehydrogenase
BBL520_RS09780	COG1263	PTS System
BBL520_RS09780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBL520_RS09780	COG2190	(PTS) system
BBL520_RS09785	COG1263	PTS System
BBL520_RS09785	COG2190	(PTS) system
BBL520_RS09785	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBL520_RS09790	COG0019	diaminopimelate decarboxylase activity
BBL520_RS09800	COG1309	transcriptional regulator
BBL520_RS09810	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBL520_RS09815	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBL520_RS09825	COG0765	amino acid transport
BBL520_RS09840	COG1126	abc transporter atp-binding protein
BBL520_RS09845	COG0167	dihydroorotate dehydrogenase activity
BBL520_RS09885	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BBL520_RS09890	COG0406	alpha-ribazole phosphatase activity
BBL520_RS09890	COG0494	nUDIX hydrolase
BBL520_RS09910	COG3833	ABC-type maltose transport systems, permease component
BBL520_RS09925	COG0584	glycerophosphoryl diester phosphodiesterase
BBL520_RS09945	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBL520_RS09965	COG3311	Transcriptional regulator
BBL520_RS09985	COG1737	Transcriptional regulator
BBL520_RS09990	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBL520_RS09995	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBL520_RS10000	COG1129	ABC transporter
BBL520_RS10010	COG1070	Carbohydrate kinase
BBL520_RS10025	COG1442	glycosyl transferase family 8
BBL520_RS10025	COG1216	Glycosyl transferase, family 2
BBL520_RS10105	COG0463	Glycosyl transferase, family 2
BBL520_RS10120	COG1088	dTDP-glucose 4,6-dehydratase activity
BBL520_RS10135	COG3409	Peptidoglycan-binding domain 1 protein
BBL520_RS10135	COG3757	hydrolase, family 25
BBL520_RS10140	COG1373	ATPase (AAA superfamily
BBL520_RS10145	COG1316	TRANSCRIPTIONal
BBL520_RS10160	COG0577	efflux transmembrane transporter activity
BBL520_RS10165	COG1129	ABC transporter
BBL520_RS10185	COG0084	hydrolase, TatD family'
BBL520_RS10190	COG1132	(ABC) transporter
BBL520_RS10195	COG1132	(ABC) transporter
BBL520_RS10215	COG0395	ABC-type sugar transport system, permease component
BBL520_RS10220	COG1175	transmembrane transport
BBL520_RS10230	COG1609	Transcriptional regulator
BBL520_RS10235	COG1874	Beta-galactosidase
BBL520_RS10255	COG4166	transmembrane transport
BBL520_RS10275	COG3579	cysteine-type endopeptidase activity
BBL520_RS10330	COG1846	Transcriptional regulator
BBL520_RS10345	COG1113	amino acid transport
BBL520_RS10355	COG0577	efflux transmembrane transporter activity
BBL520_RS10355	COG1136	(ABC) transporter
BBL520_RS10360	COG1113	amino acid transport
BBL520_RS10380	COG1609	Transcriptional regulator
BBL520_RS10390	COG0588	phosphoglycerate mutase activity
BBL520_RS10465	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BBL520_RS10470	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBL520_RS10475	COG0366	Alpha amylase catalytic
BBL520_RS10480	COG0395	ABC-type sugar transport system, permease component
BBL520_RS10485	COG1175	transmembrane transport
BBL520_RS10510	COG0037	tRNA processing
BBL520_RS10510	COG0590	tRNA wobble adenosine to inosine editing
BBL520_RS10515	COG0025	NhaP-type Na H and K H
BBL520_RS10520	COG0730	response to heat
BBL520_RS10545	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBL520_RS10555	COG1263	PTS System
BBL520_RS10555	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBL520_RS10555	COG2190	(PTS) system
BBL520_RS10560	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBL520_RS10560	COG1263	PTS System
BBL520_RS10570	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBL520_RS10590	COG3842	ATPase activity
BBL520_RS10610	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBL520_RS10615	COG1215	transferase activity, transferring glycosyl groups
BBL520_RS10625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBL520_RS10670	COG3583	domain protein
BBL520_RS10690	COG0617	tRNA 3'-terminal CCA addition
BBL520_RS10710	COG0492	ferredoxin-NADP+ reductase activity
BBL520_RS10715	COG1475	DNA binding
BBL520_RS10720	COG1192	Involved in chromosome partitioning
BBL520_RS10730	COG1847	R3H domain protein