locus-tag	class	description
NRBB01_RS00015	COG0592	DNA-directed DNA polymerase activity
NRBB01_RS00030	COG0187	DNA topoisomerase II activity
NRBB01_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRBB01_RS00045	COG1609	Transcriptional regulator
NRBB01_RS00055	COG3250	beta-galactosidase activity
NRBB01_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NRBB01_RS00105	COG0783	Belongs to the Dps family
NRBB01_RS00110	COG1253	flavin adenine dinucleotide binding
NRBB01_RS00175	COG2203	Gaf domain
NRBB01_RS00175	COG3706	GGDEF domain
NRBB01_RS00175	COG4251	negative regulation of phosphorylation
NRBB01_RS00175	COG5001	Diguanylate cyclase
NRBB01_RS00195	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NRBB01_RS00205	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRBB01_RS00220	COG0180	Tryptophanyl-tRNA synthetase
NRBB01_RS00230	COG2197	response regulator
NRBB01_RS00250	COG0058	SHG alpha-glucan phosphorylase activity
NRBB01_RS00290	COG0515	serine threonine protein kinase
NRBB01_RS00295	COG0768	penicillin binding
NRBB01_RS00330	COG0071	Belongs to the small heat shock protein (HSP20) family
NRBB01_RS00335	COG0697	spore germination
NRBB01_RS00345	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NRBB01_RS00350	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRBB01_RS00385	COG0494	nUDIX hydrolase
NRBB01_RS00405	COG0343	queuine tRNA-ribosyltransferase activity
NRBB01_RS00440	COG0191	fructose-bisphosphate aldolase activity
NRBB01_RS00475	COG1609	Transcriptional regulator
NRBB01_RS00480	COG0477	Major facilitator Superfamily
NRBB01_RS00500	COG0366	Alpha amylase catalytic
NRBB01_RS00505	COG1609	Transcriptional regulator
NRBB01_RS00540	COG0366	Alpha amylase catalytic
NRBB01_RS00550	COG1175	transmembrane transport
NRBB01_RS00555	COG3833	ABC-type maltose transport systems, permease component
NRBB01_RS00570	COG1523	belongs to the glycosyl hydrolase 13 family
NRBB01_RS00590	COG0789	Transcriptional regulator
NRBB01_RS00605	COG1028	Short-chain dehydrogenase reductase Sdr
NRBB01_RS00610	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRBB01_RS00615	COG0586	Pfam SNARE associated Golgi protein
NRBB01_RS00660	COG1309	transcriptional regulator
NRBB01_RS00710	COG0527	aspartate kinase activity
NRBB01_RS00730	COG1940	carbohydrate kinase activity
NRBB01_RS00735	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NRBB01_RS00745	COG0747	negative chemotaxis
NRBB01_RS00755	COG0444	Belongs to the ABC transporter superfamily
NRBB01_RS00760	COG4608	Belongs to the ABC transporter superfamily
NRBB01_RS00765	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB01_RS00790	COG2186	Transcriptional regulator
NRBB01_RS00825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRBB01_RS00825	COG1754	DNA topoisomerase type I activity
NRBB01_RS00835	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NRBB01_RS00850	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRBB01_RS00940	COG0672	)-iron permease
NRBB01_RS00945	COG3470	protein probably involved in high-affinity Fe2 transport
NRBB01_RS00960	COG0577	efflux transmembrane transporter activity
NRBB01_RS00965	COG1136	(ABC) transporter
NRBB01_RS01000	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NRBB01_RS01005	COG0363	glucosamine-6-phosphate deaminase activity
NRBB01_RS01035	COG1216	Glycosyl transferase, family 2
NRBB01_RS01035	COG1442	glycosyl transferase family 8
NRBB01_RS01040	COG1309	transcriptional regulator
NRBB01_RS01060	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NRBB01_RS01070	COG0305	Participates in initiation and elongation during chromosome replication
NRBB01_RS01075	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRBB01_RS01080	COG3442	glutamine amidotransferase
NRBB01_RS01115	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRBB01_RS01165	COG1131	(ABC) transporter
NRBB01_RS01205	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NRBB01_RS01215	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRBB01_RS01225	COG1937	Protein conserved in bacteria
NRBB01_RS01320	COG2182	Extracellular solute-binding protein
NRBB01_RS01330	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS01370	COG0745	RESPONSE REGULATOR receiver
NRBB01_RS01385	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NRBB01_RS01410	COG0356	it plays a direct role in the translocation of protons across the membrane
NRBB01_RS01445	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NRBB01_RS01485	COG0251	oxidation-reduction process
NRBB01_RS01520	COG3842	ATPase activity
NRBB01_RS01535	COG1027	Aspartate ammonia-lyase
NRBB01_RS01545	COG0730	response to heat
NRBB01_RS01550	COG0641	radical SAM
NRBB01_RS01555	COG1609	Transcriptional regulator
NRBB01_RS01560	COG3119	arylsulfatase activity
NRBB01_RS01580	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS01585	COG1373	ATPase (AAA superfamily
NRBB01_RS01605	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NRBB01_RS01625	COG0475	glutathione-regulated potassium exporter activity
NRBB01_RS01625	COG0569	domain protein
NRBB01_RS01680	COG1136	(ABC) transporter
NRBB01_RS01690	COG1704	LemA family
NRBB01_RS01725	COG1837	Belongs to the UPF0109 family
NRBB01_RS01760	COG0505	Belongs to the CarA family
NRBB01_RS01775	COG0488	(ABC) transporter
NRBB01_RS01780	COG1487	ribonuclease activity
NRBB01_RS01790	COG0440	acetolactate synthase activity
NRBB01_RS01830	COG0667	Aldo Keto reductase
NRBB01_RS01880	COG1116	anion transmembrane transporter activity
NRBB01_RS01905	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NRBB01_RS01910	COG1609	Transcriptional regulator
NRBB01_RS01925	COG2814	Major facilitator Superfamily
NRBB01_RS01925	COG0477	Major facilitator Superfamily
NRBB01_RS01935	COG4988	ABC transporter
NRBB01_RS01950	COG1653	transport
NRBB01_RS01955	COG1175	transmembrane transport
NRBB01_RS01960	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS01975	COG0656	L-ascorbic acid biosynthetic process
NRBB01_RS01995	COG2814	Major facilitator Superfamily
NRBB01_RS02010	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRBB01_RS02020	COG2826	transposase and inactivated derivatives, IS30 family
NRBB01_RS02025	COG0438	transferase activity, transferring glycosyl groups
NRBB01_RS02030	COG0438	transferase activity, transferring glycosyl groups
NRBB01_RS02050	COG0463	Glycosyl transferase, family 2
NRBB01_RS02055	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
NRBB01_RS02155	COG0489	protein tyrosine kinase activity
NRBB01_RS02215	COG0095	Lipoate-protein ligase
NRBB01_RS02220	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRBB01_RS02225	COG4499	WXG100 protein secretion system (Wss), protein YukC
NRBB01_RS02225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRBB01_RS02230	COG1902	pentaerythritol trinitrate reductase activity
NRBB01_RS02235	COG0167	dihydroorotate dehydrogenase activity
NRBB01_RS02240	COG1349	DNA-binding transcription factor activity
NRBB01_RS02250	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NRBB01_RS02275	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRBB01_RS02310	COG0714	Associated with various cellular activities
NRBB01_RS02325	COG0210	DNA helicase
NRBB01_RS02345	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRBB01_RS02375	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NRBB01_RS02380	COG2884	Cell division ATP-binding protein ftsE
NRBB01_RS02385	COG2177	Part of the ABC transporter FtsEX involved in
NRBB01_RS02390	COG3942	CHAP domain
NRBB01_RS02390	COG1388	LysM domain
NRBB01_RS02415	COG1126	abc transporter atp-binding protein
NRBB01_RS02425	COG0564	pseudouridine synthase activity
NRBB01_RS02430	COG1609	Transcriptional regulator
NRBB01_RS02440	COG1175	transmembrane transport
NRBB01_RS02445	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS02455	COG1653	transport
NRBB01_RS02475	COG0601	transmembrane transport
NRBB01_RS02480	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRBB01_RS02490	COG4608	Belongs to the ABC transporter superfamily
NRBB01_RS02500	COG0626	cystathionine gamma-synthase activity
NRBB01_RS02505	COG0514	ATP-dependent DNA helicase (RecQ)
NRBB01_RS02520	COG0531	amino acid
NRBB01_RS02525	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRBB01_RS02535	COG0358	DNA primase activity
NRBB01_RS02560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRBB01_RS02600	COG1609	Transcriptional regulator
NRBB01_RS02605	COG0366	Alpha amylase catalytic
NRBB01_RS02630	COG0577	efflux transmembrane transporter activity
NRBB01_RS02630	COG1136	(ABC) transporter
NRBB01_RS02640	COG0577	efflux transmembrane transporter activity
NRBB01_RS02640	COG0577	efflux transmembrane transporter activity
NRBB01_RS02645	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NRBB01_RS02650	COG0604	alcohol dehydrogenase
NRBB01_RS02655	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRBB01_RS02660	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRBB01_RS02705	COG0701	Predicted permease
NRBB01_RS02735	COG1012	belongs to the aldehyde dehydrogenase family
NRBB01_RS02755	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRBB01_RS02820	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRBB01_RS02835	COG0436	Aminotransferase
NRBB01_RS02855	COG0385	Bile acid
NRBB01_RS02890	COG0583	DNA-binding transcription factor activity
NRBB01_RS02920	COG1063	alcohol dehydrogenase
NRBB01_RS02950	COG1175	transmembrane transport
NRBB01_RS02970	COG0583	DNA-binding transcription factor activity
NRBB01_RS02980	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRBB01_RS03000	COG0110	maltose O-acetyltransferase activity
NRBB01_RS03005	COG0110	maltose O-acetyltransferase activity
NRBB01_RS03025	COG1250	3-hydroxyacyl-CoA dehydrogenase
NRBB01_RS03030	COG4106	trans-aconitate 2-methyltransferase activity
NRBB01_RS03055	COG1376	ErfK ybiS ycfS ynhG family protein
NRBB01_RS03060	COG0390	transport system, permease component
NRBB01_RS03065	COG1136	(ABC) transporter
NRBB01_RS03065	COG0577	efflux transmembrane transporter activity
NRBB01_RS03090	COG0284	orotidine-5'-phosphate decarboxylase activity
NRBB01_RS03100	COG2176	DNA-directed DNA polymerase activity
NRBB01_RS03120	COG0626	cystathionine gamma-synthase activity
NRBB01_RS03170	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NRBB01_RS03250	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRBB01_RS03265	COG1122	ATPase activity
NRBB01_RS03305	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRBB01_RS03315	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRBB01_RS03320	COG4721	ABC-type cobalt transport system, permease component
NRBB01_RS03325	COG1122	ATPase activity
NRBB01_RS03335	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRBB01_RS03400	COG4115	mRNA cleavage
NRBB01_RS03430	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRBB01_RS03435	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRBB01_RS03495	COG0497	DNA recombination
NRBB01_RS03550	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NRBB01_RS03580	COG0667	Aldo Keto reductase
NRBB01_RS03615	COG1760	l-serine dehydratase
NRBB01_RS03625	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRBB01_RS03650	COG1316	TRANSCRIPTIONal
NRBB01_RS03690	COG2205	protein histidine kinase activity
NRBB01_RS03695	COG0745	RESPONSE REGULATOR receiver
NRBB01_RS03715	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRBB01_RS03720	COG1121	(ABC) transporter
NRBB01_RS03735	COG0539	negative regulation of cytoplasmic translation
NRBB01_RS03755	COG0469	pyruvate kinase activity
NRBB01_RS03760	COG0494	nUDIX hydrolase
NRBB01_RS03780	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRBB01_RS03785	COG1051	belongs to the nudix hydrolase family
NRBB01_RS03840	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRBB01_RS03845	COG0857	belongs to the CobB CobQ family
NRBB01_RS03845	COG0280	phosphate acetyltransferase
NRBB01_RS03900	COG1484	DNA-dependent DNA replication
NRBB01_RS03970	COG0799	negative regulation of ribosome biogenesis
NRBB01_RS03975	COG0406	alpha-ribazole phosphatase activity
NRBB01_RS04005	COG2011	ABC-type metal ion transport system permease component
NRBB01_RS04010	COG1473	amidohydrolase
NRBB01_RS04025	COG1882	Formate acetyltransferase
NRBB01_RS04085	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRBB01_RS04090	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRBB01_RS04095	COG1611	Belongs to the LOG family
NRBB01_RS04110	COG1053	succinate dehydrogenase
NRBB01_RS04115	COG0758	DNA mediated transformation
NRBB01_RS04145	COG2873	o-acetylhomoserine
NRBB01_RS04150	COG1136	(ABC) transporter
NRBB01_RS04155	COG0577	efflux transmembrane transporter activity
NRBB01_RS04155	COG1136	(ABC) transporter
NRBB01_RS04160	COG2197	response regulator
NRBB01_RS04175	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRBB01_RS04180	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB01_RS04185	COG1126	abc transporter atp-binding protein
NRBB01_RS04190	COG0765	amino acid transport
NRBB01_RS04195	COG0765	amino acid transport
NRBB01_RS04200	COG0012	GTP binding
NRBB01_RS04225	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRBB01_RS04240	COG3177	Filamentation induced by cAMP protein fic
NRBB01_RS04290	COG1309	transcriptional regulator
NRBB01_RS04305	COG2814	Major facilitator Superfamily
NRBB01_RS04330	COG1846	Transcriptional regulator
NRBB01_RS04330	COG1940	carbohydrate kinase activity
NRBB01_RS04345	COG0477	Major facilitator Superfamily
NRBB01_RS04350	COG3119	arylsulfatase activity
NRBB01_RS04355	COG0641	radical SAM
NRBB01_RS04360	COG0730	response to heat
NRBB01_RS04400	COG2233	PERMEase
NRBB01_RS04405	COG0513	Belongs to the DEAD box helicase family
NRBB01_RS04410	COG0366	Alpha amylase catalytic
NRBB01_RS04415	COG0306	phosphate transporter
NRBB01_RS04425	COG2197	response regulator
NRBB01_RS04430	COG4585	Histidine kinase
NRBB01_RS04435	COG1131	(ABC) transporter
NRBB01_RS04465	COG3340	Belongs to the peptidase S51 family
NRBB01_RS04470	COG1335	isochorismatase
NRBB01_RS04490	COG3655	Transcriptional regulator
NRBB01_RS04530	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NRBB01_RS04610	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NRBB01_RS04635	COG0719	Fe-S assembly protein
NRBB01_RS04640	COG0396	ATPase activity
NRBB01_RS04645	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRBB01_RS04655	COG2151	metal-sulfur cluster biosynthetic enzyme
NRBB01_RS04675	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRBB01_RS04680	COG0537	adenosine 5'-monophosphoramidase activity
NRBB01_RS04705	COG1022	Amp-dependent synthetase and ligase
NRBB01_RS04710	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NRBB01_RS04735	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRBB01_RS04745	COG2860	membrane
NRBB01_RS04785	COG0067	glutamate synthase
NRBB01_RS04785	COG0070	glutamate synthase
NRBB01_RS04785	COG0069	glutamate synthase activity
NRBB01_RS04795	COG4166	transmembrane transport
NRBB01_RS04810	COG0297	glycogen (starch) synthase activity
NRBB01_RS04815	COG1119	ATPase activity
NRBB01_RS04825	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRBB01_RS04850	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NRBB01_RS04860	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NRBB01_RS04880	COG0588	phosphoglycerate mutase activity
NRBB01_RS04890	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NRBB01_RS04915	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NRBB01_RS04920	COG0284	orotidine-5'-phosphate decarboxylase activity
NRBB01_RS04925	COG0543	2 iron, 2 sulfur cluster binding
NRBB01_RS04930	COG0167	dihydroorotate dehydrogenase activity
NRBB01_RS04950	COG0583	DNA-binding transcription factor activity
NRBB01_RS04965	COG0488	(ABC) transporter
NRBB01_RS04970	COG4221	oxidoreductase activity
NRBB01_RS05005	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NRBB01_RS05030	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRBB01_RS05045	COG0436	Aminotransferase
NRBB01_RS05060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRBB01_RS05160	COG0045	succinate-CoA ligase (ADP-forming) activity
NRBB01_RS05185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRBB01_RS05190	COG1187	pseudouridine synthase activity
NRBB01_RS05255	COG1716	ATPase activity
NRBB01_RS05275	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
NRBB01_RS05290	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRBB01_RS05305	COG0133	tryptophan synthase activity
NRBB01_RS05310	COG2135	peptidase activity
NRBB01_RS05320	COG0833	amino acid
NRBB01_RS05395	COG0745	RESPONSE REGULATOR receiver
NRBB01_RS05410	COG4181	ATPase activity
NRBB01_RS05455	COG1131	(ABC) transporter
NRBB01_RS05485	COG1131	(ABC) transporter
NRBB01_RS05495	COG2197	response regulator
NRBB01_RS05500	COG4585	Histidine kinase
NRBB01_RS05510	COG1136	(ABC) transporter
NRBB01_RS05510	COG0577	efflux transmembrane transporter activity
NRBB01_RS05555	COG0833	amino acid
NRBB01_RS05565	COG3189	MarR family transcriptional regulator
NRBB01_RS05600	COG0693	protein deglycase activity
NRBB01_RS05610	COG0575	Belongs to the CDS family
NRBB01_RS05650	COG0516	GMP reductase activity
NRBB01_RS05685	COG3550	peptidyl-serine autophosphorylation
NRBB01_RS05725	COG4585	Histidine kinase
NRBB01_RS05730	COG2197	response regulator
NRBB01_RS05750	COG0456	acetyltransferase
NRBB01_RS05760	COG0802	atpase or kinase
NRBB01_RS05785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB01_RS05790	COG0598	Magnesium transport protein CorA
NRBB01_RS05795	COG0406	alpha-ribazole phosphatase activity
NRBB01_RS05850	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS05855	COG1175	transmembrane transport
NRBB01_RS05860	COG1653	transport
NRBB01_RS05895	COG0477	Major facilitator Superfamily
NRBB01_RS05915	COG2977	Belongs to the P-Pant transferase superfamily
NRBB01_RS05940	COG4974	Belongs to the 'phage' integrase family
NRBB01_RS05975	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRBB01_RS05975	COG0551	DNA topoisomerase type I activity
NRBB01_RS06010	COG3843	relaxase mobilization nuclease domain protein
NRBB01_RS06065	COG3942	CHAP domain
NRBB01_RS06065	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRBB01_RS06150	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
NRBB01_RS06155	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRBB01_RS06180	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRBB01_RS06195	COG1201	RNA secondary structure unwinding
NRBB01_RS06200	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRBB01_RS06210	COG0187	DNA topoisomerase II activity
NRBB01_RS06215	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRBB01_RS06225	COG0142	geranyltranstransferase activity
NRBB01_RS06245	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRBB01_RS06255	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRBB01_RS06280	COG1396	sequence-specific DNA binding
NRBB01_RS06285	COG1058	Belongs to the CinA family
NRBB01_RS06285	COG1546	Belongs to the CinA family
NRBB01_RS06315	COG2357	RelA SpoT domain protein
NRBB01_RS06330	COG2197	response regulator
NRBB01_RS06370	COG0708	Exodeoxyribonuclease III
NRBB01_RS06380	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRBB01_RS06385	COG0601	transmembrane transport
NRBB01_RS06390	COG4166	transmembrane transport
NRBB01_RS06400	COG0577	efflux transmembrane transporter activity
NRBB01_RS06400	COG1136	(ABC) transporter
NRBB01_RS06405	COG0577	efflux transmembrane transporter activity
NRBB01_RS06415	COG0287	Prephenate dehydrogenase
NRBB01_RS06430	COG1217	gtp-binding protein TYPA
NRBB01_RS06440	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRBB01_RS06440	COG1136	(ABC) transporter
NRBB01_RS06450	COG0477	Major facilitator Superfamily
NRBB01_RS06455	COG1104	cysteine desulfurase activity
NRBB01_RS06465	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRBB01_RS06470	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NRBB01_RS06480	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NRBB01_RS06485	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NRBB01_RS06500	COG1929	Belongs to the glycerate kinase type-1 family
NRBB01_RS06515	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NRBB01_RS06535	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRBB01_RS06545	COG2017	converts alpha-aldose to the beta-anomer
NRBB01_RS06550	COG2017	converts alpha-aldose to the beta-anomer
NRBB01_RS06560	COG1595	DNA-templated transcription, initiation
NRBB01_RS06580	COG1196	nuclear chromosome segregation
NRBB01_RS06585	COG0285	dihydrofolate synthase activity
NRBB01_RS06590	COG0006	proline dipeptidase activity
NRBB01_RS06610	COG1940	carbohydrate kinase activity
NRBB01_RS06615	COG1940	carbohydrate kinase activity
NRBB01_RS06635	COG0738	Major facilitator superfamily
NRBB01_RS06645	COG4974	Belongs to the 'phage' integrase family
NRBB01_RS06885	COG3723	Recombinational DNA repair protein, rece pathway
NRBB01_RS06890	COG5377	YqaJ viral recombinase family
NRBB01_RS06910	COG0270	DNA (cytosine-5-)-methyltransferase activity
NRBB01_RS06995	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRBB01_RS07005	COG0768	penicillin binding
NRBB01_RS07030	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRBB01_RS07060	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRBB01_RS07070	COG1643	Atp-dependent helicase
NRBB01_RS07075	COG2814	Major facilitator Superfamily
NRBB01_RS07125	COG0656	L-ascorbic acid biosynthetic process
NRBB01_RS07135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB01_RS07175	COG4716	Myosin-crossreactive antigen
NRBB01_RS07190	COG0587	DNA-directed DNA polymerase activity
NRBB01_RS07230	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRBB01_RS07255	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRBB01_RS07260	COG0351	phosphomethylpyrimidine kinase
NRBB01_RS07260	COG0352	thiamine-phosphate diphosphorylase activity
NRBB01_RS07275	COG2271	Major facilitator Superfamily
NRBB01_RS07285	COG2197	response regulator
NRBB01_RS07355	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
NRBB01_RS07360	COG2814	Major facilitator Superfamily
NRBB01_RS07365	COG0745	RESPONSE REGULATOR receiver
NRBB01_RS07375	COG4581	dead DEAH box helicase
NRBB01_RS07380	COG2326	polyphosphate kinase activity
NRBB01_RS07385	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRBB01_RS07390	COG1279	arginine transmembrane transporter activity
NRBB01_RS07400	COG0765	amino acid transport
NRBB01_RS07405	COG0765	amino acid transport
NRBB01_RS07410	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB01_RS07415	COG1126	abc transporter atp-binding protein
NRBB01_RS07435	COG1196	nuclear chromosome segregation
NRBB01_RS07450	COG0477	Major facilitator Superfamily
NRBB01_RS07465	COG0402	S-adenosylhomocysteine deaminase activity
NRBB01_RS07485	COG1278	Cold shock
NRBB01_RS07490	COG2205	protein histidine kinase activity
NRBB01_RS07495	COG0745	RESPONSE REGULATOR receiver
NRBB01_RS07515	COG1278	Cold shock
NRBB01_RS07530	COG0714	Associated with various cellular activities
NRBB01_RS07575	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRBB01_RS07605	COG4122	O-methyltransferase activity
NRBB01_RS07610	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRBB01_RS07620	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRBB01_RS07625	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRBB01_RS07625	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRBB01_RS07625	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRBB01_RS07640	COG1011	Hydrolase
NRBB01_RS07650	COG0586	Pfam SNARE associated Golgi protein
NRBB01_RS07655	COG0560	Phosphoserine phosphatase
NRBB01_RS07660	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRBB01_RS07695	COG4974	Belongs to the 'phage' integrase family
NRBB01_RS07700	COG0732	type I restriction modification DNA specificity domain
NRBB01_RS07705	COG0732	type I restriction modification DNA specificity domain
NRBB01_RS07710	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
NRBB01_RS07715	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
NRBB01_RS07730	COG3842	ATPase activity
NRBB01_RS07740	COG1176	ABC-type spermidine putrescine transport system, permease component I
NRBB01_RS07745	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
NRBB01_RS07760	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRBB01_RS07765	COG3069	C4-dicarboxylate transmembrane transporter activity
NRBB01_RS07785	COG1132	(ABC) transporter
NRBB01_RS07790	COG1132	(ABC) transporter
NRBB01_RS07835	COG1309	transcriptional regulator
NRBB01_RS07850	COG0602	queuosine metabolic process
NRBB01_RS07855	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NRBB01_RS07855	COG1328	CTP reductase activity
NRBB01_RS07860	COG1570	exodeoxyribonuclease VII activity
NRBB01_RS07865	COG1722	exodeoxyribonuclease VII activity
NRBB01_RS07870	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRBB01_RS07875	COG1022	Amp-dependent synthetase and ligase
NRBB01_RS07880	COG1970	mechanosensitive ion channel activity
NRBB01_RS07900	COG0248	Ppx GppA phosphatase
NRBB01_RS07905	COG0436	Aminotransferase
NRBB01_RS07975	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRBB01_RS07990	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRBB01_RS07995	COG0009	L-threonylcarbamoyladenylate synthase
NRBB01_RS08045	COG2814	Major facilitator Superfamily
NRBB01_RS08055	COG0242	peptide deformylase activity
NRBB01_RS08075	COG1940	carbohydrate kinase activity
NRBB01_RS08100	COG1946	Acyl-CoA thioesterase
NRBB01_RS08110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRBB01_RS08125	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRBB01_RS08130	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NRBB01_RS08155	COG1215	transferase activity, transferring glycosyl groups
NRBB01_RS08165	COG0463	Glycosyl transferase, family 2
NRBB01_RS08170	COG1454	alcohol dehydrogenase
NRBB01_RS08175	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRBB01_RS08215	COG3250	beta-galactosidase activity
NRBB01_RS08225	COG1609	Transcriptional regulator
NRBB01_RS08260	COG0577	efflux transmembrane transporter activity
NRBB01_RS08280	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRBB01_RS08300	COG0589	response to stress
NRBB01_RS08305	COG3103	Sh3 type 3 domain protein
NRBB01_RS08305	COG1388	LysM domain
NRBB01_RS08305	COG0791	NLP P60 protein
NRBB01_RS08315	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRBB01_RS08315	COG3942	CHAP domain
NRBB01_RS08330	COG5002	protein histidine kinase activity
NRBB01_RS08345	COG1575	Belongs to the MenA family. Type 1 subfamily
NRBB01_RS08350	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NRBB01_RS08360	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS08365	COG2814	Major facilitator Superfamily
NRBB01_RS08400	COG2197	response regulator
NRBB01_RS08420	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS08425	COG1175	transmembrane transport
NRBB01_RS08445	COG1803	Methylglyoxal synthase
NRBB01_RS08445	COG1597	lipid kinase activity
NRBB01_RS08475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRBB01_RS08480	COG0328	RNA-DNA hybrid ribonuclease activity
NRBB01_RS08505	COG0196	riboflavin kinase activity
NRBB01_RS08550	COG2308	Evidence 4 Homologs of previously reported genes of
NRBB01_RS08655	COG0255	Belongs to the universal ribosomal protein uL29 family
NRBB01_RS08705	COG3527	Alpha-acetolactate decarboxylase
NRBB01_RS08715	COG1454	alcohol dehydrogenase
NRBB01_RS08715	COG1012	belongs to the aldehyde dehydrogenase family
NRBB01_RS08725	COG1063	alcohol dehydrogenase
NRBB01_RS08780	COG1739	Uncharacterized protein family UPF0029
NRBB01_RS08785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRBB01_RS08795	COG2723	6-phospho-beta-galactosidase activity
NRBB01_RS08805	COG1175	transmembrane transport
NRBB01_RS08815	COG1609	Transcriptional regulator
NRBB01_RS08845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRBB01_RS08860	COG0531	amino acid
NRBB01_RS08865	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NRBB01_RS08910	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRBB01_RS08960	COG2252	PERMEase
NRBB01_RS08985	COG0745	RESPONSE REGULATOR receiver
NRBB01_RS08990	COG5002	protein histidine kinase activity
NRBB01_RS08995	COG0477	Major facilitator Superfamily
NRBB01_RS09005	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRBB01_RS09010	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRBB01_RS09025	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NRBB01_RS09040	COG0826	peptidase U32
NRBB01_RS09050	COG0742	ribosomal rna small subunit methyltransferase
NRBB01_RS09065	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NRBB01_RS09065	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NRBB01_RS09070	COG2270	Major facilitator Superfamily
NRBB01_RS09075	COG0789	Transcriptional regulator
NRBB01_RS09170	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRBB01_RS09175	COG4770	biotin carboxylase activity
NRBB01_RS09180	COG1268	BioY protein
NRBB01_RS09220	COG0250	Participates in transcription elongation, termination and antitermination
NRBB01_RS09225	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRBB01_RS09235	COG0436	Aminotransferase
NRBB01_RS09265	COG1530	ribonuclease E activity
NRBB01_RS09270	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRBB01_RS09280	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB01_RS09305	COG4948	Mandelate Racemase Muconate Lactonizing
NRBB01_RS09310	COG1609	Transcriptional regulator
NRBB01_RS09340	COG0083	homoserine kinase activity
NRBB01_RS09345	COG0460	homoserine dehydrogenase
NRBB01_RS09350	COG1263	PTS System
NRBB01_RS09350	COG2190	(PTS) system
NRBB01_RS09350	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB01_RS09355	COG2190	(PTS) system
NRBB01_RS09355	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB01_RS09355	COG1263	PTS System
NRBB01_RS09370	COG1309	transcriptional regulator
NRBB01_RS09380	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NRBB01_RS09385	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRBB01_RS09395	COG0765	amino acid transport
NRBB01_RS09410	COG1126	abc transporter atp-binding protein
NRBB01_RS09415	COG0167	dihydroorotate dehydrogenase activity
NRBB01_RS09460	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRBB01_RS09465	COG0494	nUDIX hydrolase
NRBB01_RS09465	COG0406	alpha-ribazole phosphatase activity
NRBB01_RS09485	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS09490	COG1175	transmembrane transport
NRBB01_RS09515	COG0584	glycerophosphoryl diester phosphodiesterase
NRBB01_RS09540	COG0179	Fumarylacetoacetate (FAA) hydrolase
NRBB01_RS09560	COG3311	Transcriptional regulator
NRBB01_RS09580	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB01_RS09585	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB01_RS09590	COG1129	ABC transporter
NRBB01_RS09600	COG1070	Carbohydrate kinase
NRBB01_RS09615	COG1442	glycosyl transferase family 8
NRBB01_RS09615	COG1216	Glycosyl transferase, family 2
NRBB01_RS09625	COG1368	sulfuric ester hydrolase activity
NRBB01_RS09630	COG0438	transferase activity, transferring glycosyl groups
NRBB01_RS09630	COG1216	Glycosyl transferase, family 2
NRBB01_RS09655	COG1088	dTDP-glucose 4,6-dehydratase activity
NRBB01_RS09675	COG1376	ErfK ybiS ycfS ynhG family protein
NRBB01_RS09685	COG1316	TRANSCRIPTIONal
NRBB01_RS09690	COG0577	efflux transmembrane transporter activity
NRBB01_RS09695	COG1129	ABC transporter
NRBB01_RS09720	COG0084	hydrolase, TatD family'
NRBB01_RS09725	COG1132	(ABC) transporter
NRBB01_RS09730	COG1132	(ABC) transporter
NRBB01_RS09820	COG1846	Transcriptional regulator
NRBB01_RS09835	COG1113	amino acid transport
NRBB01_RS09845	COG1136	(ABC) transporter
NRBB01_RS09845	COG0577	efflux transmembrane transporter activity
NRBB01_RS09850	COG1113	amino acid transport
NRBB01_RS09870	COG1609	Transcriptional regulator
NRBB01_RS09880	COG0588	phosphoglycerate mutase activity
NRBB01_RS09930	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NRBB01_RS09935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRBB01_RS09940	COG0366	Alpha amylase catalytic
NRBB01_RS09945	COG0395	ABC-type sugar transport system, permease component
NRBB01_RS09950	COG1175	transmembrane transport
NRBB01_RS09975	COG0590	tRNA wobble adenosine to inosine editing
NRBB01_RS09975	COG0037	tRNA processing
NRBB01_RS09980	COG0025	NhaP-type Na H and K H
NRBB01_RS09985	COG0730	response to heat
NRBB01_RS10010	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRBB01_RS10020	COG1263	PTS System
NRBB01_RS10020	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB01_RS10020	COG2190	(PTS) system
NRBB01_RS10025	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB01_RS10025	COG1263	PTS System
NRBB01_RS10035	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRBB01_RS10070	COG1609	Transcriptional regulator
NRBB01_RS10075	COG1879	ABC-type sugar transport system periplasmic component
NRBB01_RS10085	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB01_RS10095	COG3415	Transposase
NRBB01_RS10095	COG2801	Transposase and inactivated derivatives
NRBB01_RS10105	COG3842	ATPase activity
NRBB01_RS10125	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRBB01_RS10130	COG1215	transferase activity, transferring glycosyl groups
NRBB01_RS10150	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRBB01_RS10175	COG1472	Belongs to the glycosyl hydrolase 3 family
NRBB01_RS10190	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRBB01_RS10195	COG1472	Belongs to the glycosyl hydrolase 3 family
NRBB01_RS10215	COG3583	domain protein
NRBB01_RS10235	COG0617	tRNA 3'-terminal CCA addition
NRBB01_RS10255	COG0492	ferredoxin-NADP+ reductase activity
NRBB01_RS10260	COG1475	DNA binding
NRBB01_RS10265	COG1192	Involved in chromosome partitioning
NRBB01_RS10275	COG1847	R3H domain protein