locus-tag	class	description
NRBB52_RS00015	COG0592	DNA-directed DNA polymerase activity
NRBB52_RS00030	COG0187	DNA topoisomerase II activity
NRBB52_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRBB52_RS00045	COG1609	Transcriptional regulator
NRBB52_RS00055	COG3250	beta-galactosidase activity
NRBB52_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NRBB52_RS00155	COG0783	Belongs to the Dps family
NRBB52_RS00160	COG1253	flavin adenine dinucleotide binding
NRBB52_RS00245	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NRBB52_RS00255	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRBB52_RS00270	COG0180	Tryptophanyl-tRNA synthetase
NRBB52_RS00280	COG2197	response regulator
NRBB52_RS00300	COG0058	SHG alpha-glucan phosphorylase activity
NRBB52_RS00340	COG0515	serine threonine protein kinase
NRBB52_RS00345	COG0768	penicillin binding
NRBB52_RS00380	COG0071	Belongs to the small heat shock protein (HSP20) family
NRBB52_RS00385	COG0697	spore germination
NRBB52_RS00395	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NRBB52_RS00400	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRBB52_RS00435	COG0494	nUDIX hydrolase
NRBB52_RS00455	COG0343	queuine tRNA-ribosyltransferase activity
NRBB52_RS00485	COG0697	spore germination
NRBB52_RS00490	COG0191	fructose-bisphosphate aldolase activity
NRBB52_RS00525	COG1609	Transcriptional regulator
NRBB52_RS00530	COG0477	Major facilitator Superfamily
NRBB52_RS00560	COG0366	Alpha amylase catalytic
NRBB52_RS00565	COG1609	Transcriptional regulator
NRBB52_RS00605	COG1175	transmembrane transport
NRBB52_RS00610	COG3833	ABC-type maltose transport systems, permease component
NRBB52_RS00620	COG1609	Transcriptional regulator
NRBB52_RS00625	COG1523	belongs to the glycosyl hydrolase 13 family
NRBB52_RS00645	COG0789	Transcriptional regulator
NRBB52_RS00660	COG1028	Short-chain dehydrogenase reductase Sdr
NRBB52_RS00665	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRBB52_RS00670	COG0586	Pfam SNARE associated Golgi protein
NRBB52_RS00715	COG1309	transcriptional regulator
NRBB52_RS00765	COG0527	aspartate kinase activity
NRBB52_RS00785	COG1940	carbohydrate kinase activity
NRBB52_RS00790	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NRBB52_RS00800	COG0747	negative chemotaxis
NRBB52_RS00810	COG0444	Belongs to the ABC transporter superfamily
NRBB52_RS00815	COG4608	Belongs to the ABC transporter superfamily
NRBB52_RS00820	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB52_RS00845	COG2186	Transcriptional regulator
NRBB52_RS00880	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRBB52_RS00880	COG1754	DNA topoisomerase type I activity
NRBB52_RS00890	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NRBB52_RS00895	COG1609	Transcriptional regulator
NRBB52_RS00905	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRBB52_RS00990	COG0672	)-iron permease
NRBB52_RS00995	COG3470	protein probably involved in high-affinity Fe2 transport
NRBB52_RS01010	COG0577	efflux transmembrane transporter activity
NRBB52_RS01015	COG1136	(ABC) transporter
NRBB52_RS01050	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NRBB52_RS01055	COG0363	glucosamine-6-phosphate deaminase activity
NRBB52_RS01085	COG1442	glycosyl transferase family 8
NRBB52_RS01085	COG1216	Glycosyl transferase, family 2
NRBB52_RS01090	COG1309	transcriptional regulator
NRBB52_RS01110	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NRBB52_RS01120	COG0305	Participates in initiation and elongation during chromosome replication
NRBB52_RS01125	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRBB52_RS01130	COG3442	glutamine amidotransferase
NRBB52_RS01165	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRBB52_RS01250	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NRBB52_RS01260	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRBB52_RS01270	COG1937	Protein conserved in bacteria
NRBB52_RS01290	COG1131	(ABC) transporter
NRBB52_RS01365	COG2182	Extracellular solute-binding protein
NRBB52_RS01375	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS01415	COG0745	RESPONSE REGULATOR receiver
NRBB52_RS01430	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NRBB52_RS01445	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
NRBB52_RS01520	COG4695	Portal protein
NRBB52_RS01590	COG0356	it plays a direct role in the translocation of protons across the membrane
NRBB52_RS01625	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NRBB52_RS01665	COG0251	oxidation-reduction process
NRBB52_RS01700	COG3842	ATPase activity
NRBB52_RS01715	COG1027	Aspartate ammonia-lyase
NRBB52_RS01750	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NRBB52_RS01770	COG0475	glutathione-regulated potassium exporter activity
NRBB52_RS01770	COG0569	domain protein
NRBB52_RS01840	COG1704	LemA family
NRBB52_RS01875	COG1837	Belongs to the UPF0109 family
NRBB52_RS01910	COG0519	Catalyzes the synthesis of GMP from XMP
NRBB52_RS01915	COG0488	(ABC) transporter
NRBB52_RS01920	COG1487	ribonuclease activity
NRBB52_RS01930	COG0440	acetolactate synthase activity
NRBB52_RS01970	COG0667	Aldo Keto reductase
NRBB52_RS02020	COG1116	anion transmembrane transporter activity
NRBB52_RS02045	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NRBB52_RS02050	COG1609	Transcriptional regulator
NRBB52_RS02070	COG4988	ABC transporter
NRBB52_RS02085	COG1653	transport
NRBB52_RS02090	COG1175	transmembrane transport
NRBB52_RS02095	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS02110	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NRBB52_RS02120	COG0656	L-ascorbic acid biosynthetic process
NRBB52_RS02140	COG2814	Major facilitator Superfamily
NRBB52_RS02155	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRBB52_RS02165	COG0438	transferase activity, transferring glycosyl groups
NRBB52_RS02180	COG1216	Glycosyl transferase, family 2
NRBB52_RS02180	COG1442	glycosyl transferase family 8
NRBB52_RS02185	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
NRBB52_RS02195	COG1216	Glycosyl transferase, family 2
NRBB52_RS02225	COG1484	DNA-dependent DNA replication
NRBB52_RS02310	COG0489	protein tyrosine kinase activity
NRBB52_RS02370	COG0095	Lipoate-protein ligase
NRBB52_RS02375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRBB52_RS02380	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRBB52_RS02380	COG4499	WXG100 protein secretion system (Wss), protein YukC
NRBB52_RS02385	COG1902	pentaerythritol trinitrate reductase activity
NRBB52_RS02390	COG0167	dihydroorotate dehydrogenase activity
NRBB52_RS02395	COG1349	DNA-binding transcription factor activity
NRBB52_RS02405	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NRBB52_RS02430	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRBB52_RS02465	COG0714	Associated with various cellular activities
NRBB52_RS02480	COG0210	DNA helicase
NRBB52_RS02500	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRBB52_RS02530	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NRBB52_RS02535	COG2884	Cell division ATP-binding protein ftsE
NRBB52_RS02540	COG2177	Part of the ABC transporter FtsEX involved in
NRBB52_RS02545	COG1388	LysM domain
NRBB52_RS02545	COG3942	CHAP domain
NRBB52_RS02570	COG1126	abc transporter atp-binding protein
NRBB52_RS02580	COG0564	pseudouridine synthase activity
NRBB52_RS02585	COG1609	Transcriptional regulator
NRBB52_RS02595	COG1175	transmembrane transport
NRBB52_RS02600	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS02610	COG1653	transport
NRBB52_RS02625	COG4166	transmembrane transport
NRBB52_RS02630	COG0601	transmembrane transport
NRBB52_RS02635	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRBB52_RS02645	COG4608	Belongs to the ABC transporter superfamily
NRBB52_RS02655	COG0626	cystathionine gamma-synthase activity
NRBB52_RS02660	COG0514	ATP-dependent DNA helicase (RecQ)
NRBB52_RS02675	COG0531	amino acid
NRBB52_RS02680	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRBB52_RS02690	COG0358	DNA primase activity
NRBB52_RS02715	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRBB52_RS02720	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NRBB52_RS02755	COG1609	Transcriptional regulator
NRBB52_RS02760	COG0366	Alpha amylase catalytic
NRBB52_RS02785	COG0577	efflux transmembrane transporter activity
NRBB52_RS02785	COG1136	(ABC) transporter
NRBB52_RS02795	COG0577	efflux transmembrane transporter activity
NRBB52_RS02795	COG1136	(ABC) transporter
NRBB52_RS02800	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NRBB52_RS02805	COG0604	alcohol dehydrogenase
NRBB52_RS02810	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRBB52_RS02815	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRBB52_RS02885	COG1012	belongs to the aldehyde dehydrogenase family
NRBB52_RS02910	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRBB52_RS02975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRBB52_RS02990	COG0436	Aminotransferase
NRBB52_RS03010	COG0385	Bile acid
NRBB52_RS03045	COG0583	DNA-binding transcription factor activity
NRBB52_RS03075	COG1063	alcohol dehydrogenase
NRBB52_RS03085	COG5002	protein histidine kinase activity
NRBB52_RS03095	COG2755	lipolytic protein G-D-S-L family
NRBB52_RS03095	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
NRBB52_RS03105	COG0747	negative chemotaxis
NRBB52_RS03110	COG0601	transmembrane transport
NRBB52_RS03115	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRBB52_RS03125	COG4608	Belongs to the ABC transporter superfamily
NRBB52_RS03135	COG1609	Transcriptional regulator
NRBB52_RS03165	COG0583	DNA-binding transcription factor activity
NRBB52_RS03175	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRBB52_RS03195	COG0110	maltose O-acetyltransferase activity
NRBB52_RS03200	COG0110	maltose O-acetyltransferase activity
NRBB52_RS03225	COG2199	diguanylate cyclase activity
NRBB52_RS03230	COG0390	transport system, permease component
NRBB52_RS03235	COG1136	(ABC) transporter
NRBB52_RS03235	COG0577	efflux transmembrane transporter activity
NRBB52_RS03260	COG0284	orotidine-5'-phosphate decarboxylase activity
NRBB52_RS03270	COG2176	DNA-directed DNA polymerase activity
NRBB52_RS03290	COG0626	cystathionine gamma-synthase activity
NRBB52_RS03340	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NRBB52_RS03420	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRBB52_RS03435	COG1122	ATPase activity
NRBB52_RS03475	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRBB52_RS03485	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRBB52_RS03490	COG4721	ABC-type cobalt transport system, permease component
NRBB52_RS03495	COG1122	ATPase activity
NRBB52_RS03505	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRBB52_RS03590	COG4115	mRNA cleavage
NRBB52_RS03620	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRBB52_RS03625	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRBB52_RS03680	COG0497	DNA recombination
NRBB52_RS03685	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRBB52_RS03735	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NRBB52_RS03740	COG1472	Belongs to the glycosyl hydrolase 3 family
NRBB52_RS03750	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRBB52_RS03750	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRBB52_RS03765	COG0667	Aldo Keto reductase
NRBB52_RS03800	COG1760	l-serine dehydratase
NRBB52_RS03810	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRBB52_RS03835	COG1316	TRANSCRIPTIONal
NRBB52_RS03875	COG2205	protein histidine kinase activity
NRBB52_RS03880	COG0745	RESPONSE REGULATOR receiver
NRBB52_RS03905	COG1121	(ABC) transporter
NRBB52_RS03920	COG0539	negative regulation of cytoplasmic translation
NRBB52_RS03940	COG0469	pyruvate kinase activity
NRBB52_RS03945	COG0494	nUDIX hydrolase
NRBB52_RS03965	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRBB52_RS03970	COG1051	belongs to the nudix hydrolase family
NRBB52_RS04055	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRBB52_RS04060	COG0857	belongs to the CobB CobQ family
NRBB52_RS04060	COG0280	phosphate acetyltransferase
NRBB52_RS04100	COG0799	negative regulation of ribosome biogenesis
NRBB52_RS04105	COG0406	alpha-ribazole phosphatase activity
NRBB52_RS04135	COG2011	ABC-type metal ion transport system permease component
NRBB52_RS04140	COG1473	amidohydrolase
NRBB52_RS04155	COG1882	Formate acetyltransferase
NRBB52_RS04215	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRBB52_RS04220	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRBB52_RS04225	COG1611	Belongs to the LOG family
NRBB52_RS04240	COG1053	succinate dehydrogenase
NRBB52_RS04245	COG0758	DNA mediated transformation
NRBB52_RS04275	COG2873	o-acetylhomoserine
NRBB52_RS04280	COG1136	(ABC) transporter
NRBB52_RS04285	COG0577	efflux transmembrane transporter activity
NRBB52_RS04285	COG1136	(ABC) transporter
NRBB52_RS04290	COG2197	response regulator
NRBB52_RS04305	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRBB52_RS04310	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB52_RS04315	COG1126	abc transporter atp-binding protein
NRBB52_RS04320	COG0765	amino acid transport
NRBB52_RS04325	COG0765	amino acid transport
NRBB52_RS04330	COG0012	GTP binding
NRBB52_RS04355	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRBB52_RS04370	COG3177	Filamentation induced by cAMP protein fic
NRBB52_RS04420	COG1309	transcriptional regulator
NRBB52_RS04435	COG2814	Major facilitator Superfamily
NRBB52_RS04450	COG0515	serine threonine protein kinase
NRBB52_RS04450	COG2815	serine threonine protein kinase
NRBB52_RS04505	COG1940	carbohydrate kinase activity
NRBB52_RS04505	COG1846	Transcriptional regulator
NRBB52_RS04510	COG1940	carbohydrate kinase activity
NRBB52_RS04520	COG0477	Major facilitator Superfamily
NRBB52_RS04525	COG3119	arylsulfatase activity
NRBB52_RS04530	COG0641	radical SAM
NRBB52_RS04535	COG0730	response to heat
NRBB52_RS04575	COG2233	PERMEase
NRBB52_RS04580	COG0513	Belongs to the DEAD box helicase family
NRBB52_RS04585	COG0366	Alpha amylase catalytic
NRBB52_RS04590	COG0306	phosphate transporter
NRBB52_RS04600	COG2197	response regulator
NRBB52_RS04605	COG4585	Histidine kinase
NRBB52_RS04610	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRBB52_RS04615	COG1131	(ABC) transporter
NRBB52_RS04645	COG3340	Belongs to the peptidase S51 family
NRBB52_RS04650	COG1335	isochorismatase
NRBB52_RS04665	COG3655	Transcriptional regulator
NRBB52_RS04710	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NRBB52_RS04795	COG0402	S-adenosylhomocysteine deaminase activity
NRBB52_RS04810	COG4974	Belongs to the 'phage' integrase family
NRBB52_RS04890	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NRBB52_RS04915	COG0719	Fe-S assembly protein
NRBB52_RS04920	COG0396	ATPase activity
NRBB52_RS04925	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRBB52_RS04935	COG2151	metal-sulfur cluster biosynthetic enzyme
NRBB52_RS04955	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRBB52_RS04960	COG0537	adenosine 5'-monophosphoramidase activity
NRBB52_RS04985	COG1022	Amp-dependent synthetase and ligase
NRBB52_RS04990	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NRBB52_RS05015	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRBB52_RS05020	COG2860	membrane
NRBB52_RS05060	COG0070	glutamate synthase
NRBB52_RS05060	COG0069	glutamate synthase activity
NRBB52_RS05060	COG0067	glutamate synthase
NRBB52_RS05070	COG4166	transmembrane transport
NRBB52_RS05085	COG0297	glycogen (starch) synthase activity
NRBB52_RS05090	COG1119	ATPase activity
NRBB52_RS05100	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRBB52_RS05125	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NRBB52_RS05135	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NRBB52_RS05155	COG0588	phosphoglycerate mutase activity
NRBB52_RS05165	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NRBB52_RS05190	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NRBB52_RS05195	COG0284	orotidine-5'-phosphate decarboxylase activity
NRBB52_RS05200	COG0543	2 iron, 2 sulfur cluster binding
NRBB52_RS05205	COG0167	dihydroorotate dehydrogenase activity
NRBB52_RS05225	COG0583	DNA-binding transcription factor activity
NRBB52_RS05240	COG0488	(ABC) transporter
NRBB52_RS05245	COG4221	oxidoreductase activity
NRBB52_RS05280	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NRBB52_RS05305	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRBB52_RS05320	COG0436	Aminotransferase
NRBB52_RS05335	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRBB52_RS05360	COG1388	LysM domain
NRBB52_RS05360	COG0741	lytic transglycosylase activity
NRBB52_RS05535	COG1475	DNA binding
NRBB52_RS05615	COG4974	Belongs to the 'phage' integrase family
NRBB52_RS05700	COG0045	succinate-CoA ligase (ADP-forming) activity
NRBB52_RS05725	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRBB52_RS05730	COG1187	pseudouridine synthase activity
NRBB52_RS05795	COG1716	ATPase activity
NRBB52_RS05830	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRBB52_RS05845	COG0133	tryptophan synthase activity
NRBB52_RS05850	COG2135	peptidase activity
NRBB52_RS05860	COG0833	amino acid
NRBB52_RS05940	COG0745	RESPONSE REGULATOR receiver
NRBB52_RS05955	COG4181	ATPase activity
NRBB52_RS06000	COG1131	(ABC) transporter
NRBB52_RS06025	COG1131	(ABC) transporter
NRBB52_RS06035	COG2197	response regulator
NRBB52_RS06040	COG4585	Histidine kinase
NRBB52_RS06050	COG0577	efflux transmembrane transporter activity
NRBB52_RS06050	COG1136	(ABC) transporter
NRBB52_RS06105	COG0596	Alpha beta hydrolase
NRBB52_RS06120	COG1051	belongs to the nudix hydrolase family
NRBB52_RS06125	COG0706	membrane insertase activity
NRBB52_RS06145	COG0833	amino acid
NRBB52_RS06155	COG3189	MarR family transcriptional regulator
NRBB52_RS06190	COG0693	protein deglycase activity
NRBB52_RS06200	COG0575	Belongs to the CDS family
NRBB52_RS06240	COG0516	GMP reductase activity
NRBB52_RS06275	COG3550	peptidyl-serine autophosphorylation
NRBB52_RS06320	COG4585	Histidine kinase
NRBB52_RS06325	COG2197	response regulator
NRBB52_RS06345	COG0456	acetyltransferase
NRBB52_RS06355	COG0802	atpase or kinase
NRBB52_RS06380	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB52_RS06385	COG0598	Magnesium transport protein CorA
NRBB52_RS06390	COG0406	alpha-ribazole phosphatase activity
NRBB52_RS06445	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS06450	COG1175	transmembrane transport
NRBB52_RS06455	COG1653	transport
NRBB52_RS06505	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRBB52_RS06530	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRBB52_RS06545	COG1201	RNA secondary structure unwinding
NRBB52_RS06550	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRBB52_RS06560	COG0187	DNA topoisomerase II activity
NRBB52_RS06565	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRBB52_RS06575	COG0142	geranyltranstransferase activity
NRBB52_RS06595	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRBB52_RS06605	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRBB52_RS06630	COG1396	sequence-specific DNA binding
NRBB52_RS06635	COG1546	Belongs to the CinA family
NRBB52_RS06635	COG1058	Belongs to the CinA family
NRBB52_RS06665	COG2357	RelA SpoT domain protein
NRBB52_RS06695	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRBB52_RS06720	COG0708	Exodeoxyribonuclease III
NRBB52_RS06730	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRBB52_RS06735	COG0601	transmembrane transport
NRBB52_RS06740	COG4166	transmembrane transport
NRBB52_RS06750	COG0577	efflux transmembrane transporter activity
NRBB52_RS06750	COG1136	(ABC) transporter
NRBB52_RS06755	COG0577	efflux transmembrane transporter activity
NRBB52_RS06765	COG0287	Prephenate dehydrogenase
NRBB52_RS06780	COG1217	gtp-binding protein TYPA
NRBB52_RS06790	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRBB52_RS06790	COG1136	(ABC) transporter
NRBB52_RS06800	COG0477	Major facilitator Superfamily
NRBB52_RS06815	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRBB52_RS06820	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NRBB52_RS06830	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NRBB52_RS06850	COG1929	Belongs to the glycerate kinase type-1 family
NRBB52_RS06865	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NRBB52_RS06885	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRBB52_RS06895	COG2017	converts alpha-aldose to the beta-anomer
NRBB52_RS06900	COG2017	converts alpha-aldose to the beta-anomer
NRBB52_RS06910	COG1595	DNA-templated transcription, initiation
NRBB52_RS06930	COG1196	nuclear chromosome segregation
NRBB52_RS06935	COG0285	dihydrofolate synthase activity
NRBB52_RS06940	COG0006	proline dipeptidase activity
NRBB52_RS06960	COG1940	carbohydrate kinase activity
NRBB52_RS06965	COG1940	carbohydrate kinase activity
NRBB52_RS06985	COG0738	Major facilitator superfamily
NRBB52_RS07030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRBB52_RS07040	COG0768	penicillin binding
NRBB52_RS07065	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRBB52_RS07095	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRBB52_RS07110	COG2814	Major facilitator Superfamily
NRBB52_RS07160	COG0656	L-ascorbic acid biosynthetic process
NRBB52_RS07170	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB52_RS07210	COG4716	Myosin-crossreactive antigen
NRBB52_RS07225	COG0587	DNA-directed DNA polymerase activity
NRBB52_RS07265	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRBB52_RS07290	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRBB52_RS07295	COG0351	phosphomethylpyrimidine kinase
NRBB52_RS07295	COG0352	thiamine-phosphate diphosphorylase activity
NRBB52_RS07310	COG2271	Major facilitator Superfamily
NRBB52_RS07320	COG2197	response regulator
NRBB52_RS07390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRBB52_RS07395	COG2814	Major facilitator Superfamily
NRBB52_RS07400	COG0745	RESPONSE REGULATOR receiver
NRBB52_RS07410	COG4581	dead DEAH box helicase
NRBB52_RS07415	COG2326	polyphosphate kinase activity
NRBB52_RS07420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRBB52_RS07425	COG1279	arginine transmembrane transporter activity
NRBB52_RS07435	COG0765	amino acid transport
NRBB52_RS07440	COG0765	amino acid transport
NRBB52_RS07445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB52_RS07450	COG1126	abc transporter atp-binding protein
NRBB52_RS07470	COG1196	nuclear chromosome segregation
NRBB52_RS07485	COG0477	Major facilitator Superfamily
NRBB52_RS07500	COG0589	response to stress
NRBB52_RS07510	COG1278	Cold shock
NRBB52_RS07515	COG2205	protein histidine kinase activity
NRBB52_RS07520	COG0745	RESPONSE REGULATOR receiver
NRBB52_RS07555	COG0714	Associated with various cellular activities
NRBB52_RS07600	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRBB52_RS07630	COG4122	O-methyltransferase activity
NRBB52_RS07635	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRBB52_RS07645	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRBB52_RS07650	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRBB52_RS07650	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRBB52_RS07650	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
NRBB52_RS07665	COG1011	Hydrolase
NRBB52_RS07675	COG0586	Pfam SNARE associated Golgi protein
NRBB52_RS07680	COG0560	Phosphoserine phosphatase
NRBB52_RS07685	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRBB52_RS07780	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NRBB52_RS07785	COG1518	maintenance of DNA repeat elements
NRBB52_RS07835	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRBB52_RS07840	COG3069	C4-dicarboxylate transmembrane transporter activity
NRBB52_RS07860	COG1132	(ABC) transporter
NRBB52_RS07865	COG1132	(ABC) transporter
NRBB52_RS07875	COG1472	Belongs to the glycosyl hydrolase 3 family
NRBB52_RS07915	COG1309	transcriptional regulator
NRBB52_RS07930	COG0602	queuosine metabolic process
NRBB52_RS07935	COG1328	CTP reductase activity
NRBB52_RS07935	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NRBB52_RS07940	COG1570	exodeoxyribonuclease VII activity
NRBB52_RS07945	COG1722	exodeoxyribonuclease VII activity
NRBB52_RS07950	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRBB52_RS07955	COG1022	Amp-dependent synthetase and ligase
NRBB52_RS07960	COG1970	mechanosensitive ion channel activity
NRBB52_RS07980	COG0248	Ppx GppA phosphatase
NRBB52_RS07985	COG0436	Aminotransferase
NRBB52_RS08055	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRBB52_RS08065	COG1609	Transcriptional regulator
NRBB52_RS08070	COG0366	Alpha amylase catalytic
NRBB52_RS08095	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
NRBB52_RS08105	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRBB52_RS08110	COG0009	L-threonylcarbamoyladenylate synthase
NRBB52_RS08160	COG2814	Major facilitator Superfamily
NRBB52_RS08170	COG0242	peptide deformylase activity
NRBB52_RS08190	COG1940	carbohydrate kinase activity
NRBB52_RS08215	COG1946	Acyl-CoA thioesterase
NRBB52_RS08225	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRBB52_RS08240	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRBB52_RS08245	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NRBB52_RS08270	COG1215	transferase activity, transferring glycosyl groups
NRBB52_RS08280	COG0463	Glycosyl transferase, family 2
NRBB52_RS08285	COG1454	alcohol dehydrogenase
NRBB52_RS08290	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRBB52_RS08325	COG1192	Involved in chromosome partitioning
NRBB52_RS08335	COG0488	(ABC) transporter
NRBB52_RS08360	COG1569	PIN domain
NRBB52_RS08385	COG3942	CHAP domain
NRBB52_RS08385	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRBB52_RS08465	COG1475	DNA binding
NRBB52_RS08495	COG3250	beta-galactosidase activity
NRBB52_RS08505	COG1609	Transcriptional regulator
NRBB52_RS08540	COG0577	efflux transmembrane transporter activity
NRBB52_RS08560	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRBB52_RS08580	COG0589	response to stress
NRBB52_RS08585	COG0791	NLP P60 protein
NRBB52_RS08585	COG1388	LysM domain
NRBB52_RS08585	COG3103	Sh3 type 3 domain protein
NRBB52_RS08595	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRBB52_RS08595	COG3942	CHAP domain
NRBB52_RS08610	COG5002	protein histidine kinase activity
NRBB52_RS08625	COG1575	Belongs to the MenA family. Type 1 subfamily
NRBB52_RS08630	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NRBB52_RS08640	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS08645	COG2814	Major facilitator Superfamily
NRBB52_RS08680	COG2197	response regulator
NRBB52_RS08700	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS08705	COG1175	transmembrane transport
NRBB52_RS08725	COG1597	lipid kinase activity
NRBB52_RS08725	COG1803	Methylglyoxal synthase
NRBB52_RS08755	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRBB52_RS08815	COG1609	Transcriptional regulator
NRBB52_RS08830	COG2308	Evidence 4 Homologs of previously reported genes of
NRBB52_RS08935	COG0255	Belongs to the universal ribosomal protein uL29 family
NRBB52_RS08995	COG3527	Alpha-acetolactate decarboxylase
NRBB52_RS09005	COG1454	alcohol dehydrogenase
NRBB52_RS09005	COG1012	belongs to the aldehyde dehydrogenase family
NRBB52_RS09015	COG1063	alcohol dehydrogenase
NRBB52_RS09070	COG1739	Uncharacterized protein family UPF0029
NRBB52_RS09075	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRBB52_RS09085	COG2723	6-phospho-beta-galactosidase activity
NRBB52_RS09095	COG1175	transmembrane transport
NRBB52_RS09105	COG1609	Transcriptional regulator
NRBB52_RS09120	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRBB52_RS09135	COG0531	amino acid
NRBB52_RS09140	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NRBB52_RS09185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRBB52_RS09235	COG2252	PERMEase
NRBB52_RS09260	COG0745	RESPONSE REGULATOR receiver
NRBB52_RS09265	COG5002	protein histidine kinase activity
NRBB52_RS09270	COG0477	Major facilitator Superfamily
NRBB52_RS09280	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRBB52_RS09285	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRBB52_RS09295	COG3250	beta-galactosidase activity
NRBB52_RS09300	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRBB52_RS09315	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS09320	COG1175	transmembrane transport
NRBB52_RS09325	COG1653	transport
NRBB52_RS09340	COG3579	cysteine-type endopeptidase activity
NRBB52_RS09355	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NRBB52_RS09370	COG0826	peptidase U32
NRBB52_RS09380	COG0742	ribosomal rna small subunit methyltransferase
NRBB52_RS09395	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NRBB52_RS09395	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NRBB52_RS09400	COG2270	Major facilitator Superfamily
NRBB52_RS09405	COG0789	Transcriptional regulator
NRBB52_RS09505	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRBB52_RS09510	COG4770	biotin carboxylase activity
NRBB52_RS09515	COG1268	BioY protein
NRBB52_RS09555	COG0250	Participates in transcription elongation, termination and antitermination
NRBB52_RS09560	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRBB52_RS09570	COG0436	Aminotransferase
NRBB52_RS09600	COG1530	ribonuclease E activity
NRBB52_RS09605	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRBB52_RS09615	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB52_RS09640	COG4948	Mandelate Racemase Muconate Lactonizing
NRBB52_RS09645	COG1609	Transcriptional regulator
NRBB52_RS09675	COG0083	homoserine kinase activity
NRBB52_RS09680	COG0460	homoserine dehydrogenase
NRBB52_RS09685	COG2190	(PTS) system
NRBB52_RS09685	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB52_RS09685	COG1263	PTS System
NRBB52_RS09690	COG2190	(PTS) system
NRBB52_RS09690	COG1263	PTS System
NRBB52_RS09690	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB52_RS09705	COG1309	transcriptional regulator
NRBB52_RS09715	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NRBB52_RS09720	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRBB52_RS09730	COG0765	amino acid transport
NRBB52_RS09745	COG1126	abc transporter atp-binding protein
NRBB52_RS09750	COG0167	dihydroorotate dehydrogenase activity
NRBB52_RS09795	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRBB52_RS09800	COG0494	nUDIX hydrolase
NRBB52_RS09800	COG0406	alpha-ribazole phosphatase activity
NRBB52_RS09835	COG0584	glycerophosphoryl diester phosphodiesterase
NRBB52_RS09860	COG0179	Fumarylacetoacetate (FAA) hydrolase
NRBB52_RS09880	COG3311	Transcriptional regulator
NRBB52_RS09895	COG1737	Transcriptional regulator
NRBB52_RS09900	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB52_RS09905	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB52_RS09910	COG1129	ABC transporter
NRBB52_RS09920	COG1070	Carbohydrate kinase
NRBB52_RS09935	COG1216	Glycosyl transferase, family 2
NRBB52_RS09935	COG1442	glycosyl transferase family 8
NRBB52_RS09945	COG1368	sulfuric ester hydrolase activity
NRBB52_RS09950	COG1368	sulfuric ester hydrolase activity
NRBB52_RS09975	COG1216	Glycosyl transferase, family 2
NRBB52_RS09990	COG1088	dTDP-glucose 4,6-dehydratase activity
NRBB52_RS10010	COG1316	TRANSCRIPTIONal
NRBB52_RS10015	COG0577	efflux transmembrane transporter activity
NRBB52_RS10020	COG1129	ABC transporter
NRBB52_RS10045	COG0084	hydrolase, TatD family'
NRBB52_RS10050	COG1132	(ABC) transporter
NRBB52_RS10055	COG1132	(ABC) transporter
NRBB52_RS10070	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS10075	COG1175	transmembrane transport
NRBB52_RS10085	COG1609	Transcriptional regulator
NRBB52_RS10090	COG1874	Beta-galactosidase
NRBB52_RS10155	COG3579	cysteine-type endopeptidase activity
NRBB52_RS10215	COG1846	Transcriptional regulator
NRBB52_RS10225	COG1113	amino acid transport
NRBB52_RS10235	COG0577	efflux transmembrane transporter activity
NRBB52_RS10235	COG1136	(ABC) transporter
NRBB52_RS10240	COG1113	amino acid transport
NRBB52_RS10260	COG1609	Transcriptional regulator
NRBB52_RS10270	COG0588	phosphoglycerate mutase activity
NRBB52_RS10345	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NRBB52_RS10350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRBB52_RS10355	COG0366	Alpha amylase catalytic
NRBB52_RS10360	COG0395	ABC-type sugar transport system, permease component
NRBB52_RS10365	COG1175	transmembrane transport
NRBB52_RS10390	COG0037	tRNA processing
NRBB52_RS10390	COG0590	tRNA wobble adenosine to inosine editing
NRBB52_RS10395	COG0025	NhaP-type Na H and K H
NRBB52_RS10400	COG0730	response to heat
NRBB52_RS10425	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRBB52_RS10435	COG1263	PTS System
NRBB52_RS10435	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB52_RS10435	COG2190	(PTS) system
NRBB52_RS10440	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB52_RS10440	COG1263	PTS System
NRBB52_RS10450	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRBB52_RS10485	COG1609	Transcriptional regulator
NRBB52_RS10490	COG1879	ABC-type sugar transport system periplasmic component
NRBB52_RS10500	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB52_RS10535	COG3842	ATPase activity
NRBB52_RS10540	COG2188	Transcriptional regulator
NRBB52_RS10555	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRBB52_RS10560	COG1215	transferase activity, transferring glycosyl groups
NRBB52_RS10580	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRBB52_RS10600	COG1472	Belongs to the glycosyl hydrolase 3 family
NRBB52_RS10615	COG3279	Response regulator of the LytR AlgR family
NRBB52_RS10640	COG3583	domain protein
NRBB52_RS10660	COG0617	tRNA 3'-terminal CCA addition
NRBB52_RS10680	COG0492	ferredoxin-NADP+ reductase activity
NRBB52_RS10685	COG1475	DNA binding
NRBB52_RS10690	COG1192	Involved in chromosome partitioning
NRBB52_RS10700	COG1847	R3H domain protein