locus-tag	class	description
NRBB56_RS00015	COG0592	DNA-directed DNA polymerase activity
NRBB56_RS00030	COG0187	DNA topoisomerase II activity
NRBB56_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRBB56_RS00045	COG1609	Transcriptional regulator
NRBB56_RS00055	COG3250	beta-galactosidase activity
NRBB56_RS00065	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
NRBB56_RS00100	COG0783	Belongs to the Dps family
NRBB56_RS00120	COG1609	Transcriptional regulator
NRBB56_RS00140	COG1609	Transcriptional regulator
NRBB56_RS00185	COG1609	Transcriptional regulator
NRBB56_RS00195	COG0783	Belongs to the Dps family
NRBB56_RS00200	COG1253	flavin adenine dinucleotide binding
NRBB56_RS00265	COG5001	Diguanylate cyclase
NRBB56_RS00265	COG2203	Gaf domain
NRBB56_RS00265	COG3706	GGDEF domain
NRBB56_RS00265	COG4251	negative regulation of phosphorylation
NRBB56_RS00285	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
NRBB56_RS00295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
NRBB56_RS00310	COG0180	Tryptophanyl-tRNA synthetase
NRBB56_RS00320	COG2197	response regulator
NRBB56_RS00340	COG0058	SHG alpha-glucan phosphorylase activity
NRBB56_RS00380	COG0515	serine threonine protein kinase
NRBB56_RS00385	COG0768	penicillin binding
NRBB56_RS00420	COG0071	Belongs to the small heat shock protein (HSP20) family
NRBB56_RS00425	COG0697	spore germination
NRBB56_RS00435	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
NRBB56_RS00440	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
NRBB56_RS00465	COG1216	Glycosyl transferase, family 2
NRBB56_RS00475	COG0494	nUDIX hydrolase
NRBB56_RS00500	COG0343	queuine tRNA-ribosyltransferase activity
NRBB56_RS00530	COG0697	spore germination
NRBB56_RS00535	COG0191	fructose-bisphosphate aldolase activity
NRBB56_RS00570	COG1609	Transcriptional regulator
NRBB56_RS00575	COG0477	Major facilitator Superfamily
NRBB56_RS00600	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS00620	COG1609	Transcriptional regulator
NRBB56_RS00660	COG1175	transmembrane transport
NRBB56_RS00665	COG3833	ABC-type maltose transport systems, permease component
NRBB56_RS00675	COG1609	Transcriptional regulator
NRBB56_RS00680	COG1523	belongs to the glycosyl hydrolase 13 family
NRBB56_RS00720	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRBB56_RS00725	COG0586	Pfam SNARE associated Golgi protein
NRBB56_RS00770	COG1309	transcriptional regulator
NRBB56_RS00820	COG0527	aspartate kinase activity
NRBB56_RS00840	COG1940	carbohydrate kinase activity
NRBB56_RS00845	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
NRBB56_RS00855	COG0747	negative chemotaxis
NRBB56_RS00865	COG0444	Belongs to the ABC transporter superfamily
NRBB56_RS00870	COG4608	Belongs to the ABC transporter superfamily
NRBB56_RS00875	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB56_RS00900	COG2186	Transcriptional regulator
NRBB56_RS00935	COG1754	DNA topoisomerase type I activity
NRBB56_RS00935	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRBB56_RS00945	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
NRBB56_RS00960	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
NRBB56_RS01055	COG3619	membrane
NRBB56_RS01060	COG1733	regulation of RNA biosynthetic process
NRBB56_RS01090	COG0477	Major facilitator Superfamily
NRBB56_RS01095	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
NRBB56_RS01100	COG3321	synthase
NRBB56_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
NRBB56_RS01100	COG0604	alcohol dehydrogenase
NRBB56_RS01110	COG2977	Belongs to the P-Pant transferase superfamily
NRBB56_RS01175	COG0672	)-iron permease
NRBB56_RS01190	COG0577	efflux transmembrane transporter activity
NRBB56_RS01195	COG0577	efflux transmembrane transporter activity
NRBB56_RS01200	COG1136	(ABC) transporter
NRBB56_RS01235	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
NRBB56_RS01240	COG0363	glucosamine-6-phosphate deaminase activity
NRBB56_RS01270	COG1442	glycosyl transferase family 8
NRBB56_RS01270	COG1216	Glycosyl transferase, family 2
NRBB56_RS01275	COG1309	transcriptional regulator
NRBB56_RS01295	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
NRBB56_RS01305	COG0305	Participates in initiation and elongation during chromosome replication
NRBB56_RS01310	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRBB56_RS01315	COG3442	glutamine amidotransferase
NRBB56_RS01350	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
NRBB56_RS01390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRBB56_RS01400	COG1937	Protein conserved in bacteria
NRBB56_RS01420	COG1131	(ABC) transporter
NRBB56_RS01480	COG2211	Major facilitator Superfamily
NRBB56_RS01500	COG4974	Belongs to the 'phage' integrase family
NRBB56_RS01535	COG0745	RESPONSE REGULATOR receiver
NRBB56_RS01550	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
NRBB56_RS01595	COG1484	DNA-dependent DNA replication
NRBB56_RS01610	COG4209	transmembrane transport
NRBB56_RS01615	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS01650	COG3250	beta-galactosidase activity
NRBB56_RS01745	COG4974	Belongs to the 'phage' integrase family
NRBB56_RS01760	COG0356	it plays a direct role in the translocation of protons across the membrane
NRBB56_RS01795	COG0355	proton-transporting ATP synthase activity, rotational mechanism
NRBB56_RS01835	COG0251	oxidation-reduction process
NRBB56_RS01870	COG3842	ATPase activity
NRBB56_RS01885	COG1027	Aspartate ammonia-lyase
NRBB56_RS01895	COG0730	response to heat
NRBB56_RS01900	COG0641	radical SAM
NRBB56_RS01905	COG1609	Transcriptional regulator
NRBB56_RS01910	COG3119	arylsulfatase activity
NRBB56_RS01930	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS01935	COG1373	ATPase (AAA superfamily
NRBB56_RS01955	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
NRBB56_RS01970	COG0569	domain protein
NRBB56_RS01970	COG0475	glutathione-regulated potassium exporter activity
NRBB56_RS02025	COG1136	(ABC) transporter
NRBB56_RS02035	COG1704	LemA family
NRBB56_RS02070	COG1837	Belongs to the UPF0109 family
NRBB56_RS02105	COG0505	Belongs to the CarA family
NRBB56_RS02110	COG0488	(ABC) transporter
NRBB56_RS02115	COG1487	ribonuclease activity
NRBB56_RS02125	COG0440	acetolactate synthase activity
NRBB56_RS02170	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
NRBB56_RS02200	COG0667	Aldo Keto reductase
NRBB56_RS02250	COG1116	anion transmembrane transporter activity
NRBB56_RS02275	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
NRBB56_RS02280	COG1609	Transcriptional regulator
NRBB56_RS02295	COG0477	Major facilitator Superfamily
NRBB56_RS02295	COG2814	Major facilitator Superfamily
NRBB56_RS02305	COG4988	ABC transporter
NRBB56_RS02320	COG1653	transport
NRBB56_RS02340	COG3867	Arabinogalactan endo-beta-1,4-galactanase
NRBB56_RS02350	COG0656	L-ascorbic acid biosynthetic process
NRBB56_RS02370	COG2814	Major facilitator Superfamily
NRBB56_RS02385	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRBB56_RS02420	COG1216	Glycosyl transferase, family 2
NRBB56_RS02420	COG1442	glycosyl transferase family 8
NRBB56_RS02440	COG4974	Belongs to the 'phage' integrase family
NRBB56_RS02450	COG1215	transferase activity, transferring glycosyl groups
NRBB56_RS02505	COG2801	Transposase and inactivated derivatives
NRBB56_RS02515	COG1216	Glycosyl transferase, family 2
NRBB56_RS02515	COG1442	glycosyl transferase family 8
NRBB56_RS02530	COG0438	transferase activity, transferring glycosyl groups
NRBB56_RS02540	COG1215	transferase activity, transferring glycosyl groups
NRBB56_RS02545	COG0215	cysteine-tRNA ligase activity
NRBB56_RS02560	COG3328	transposase activity
NRBB56_RS02585	COG0489	protein tyrosine kinase activity
NRBB56_RS02645	COG0095	Lipoate-protein ligase
NRBB56_RS02650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRBB56_RS02655	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
NRBB56_RS02655	COG4499	WXG100 protein secretion system (Wss), protein YukC
NRBB56_RS02660	COG1902	pentaerythritol trinitrate reductase activity
NRBB56_RS02665	COG0167	dihydroorotate dehydrogenase activity
NRBB56_RS02670	COG1349	DNA-binding transcription factor activity
NRBB56_RS02680	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
NRBB56_RS02705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
NRBB56_RS02740	COG0714	Associated with various cellular activities
NRBB56_RS02755	COG0210	DNA helicase
NRBB56_RS02775	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
NRBB56_RS02805	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
NRBB56_RS02810	COG2884	Cell division ATP-binding protein ftsE
NRBB56_RS02815	COG2177	Part of the ABC transporter FtsEX involved in
NRBB56_RS02820	COG3942	CHAP domain
NRBB56_RS02820	COG1388	LysM domain
NRBB56_RS02845	COG1126	abc transporter atp-binding protein
NRBB56_RS02855	COG0564	pseudouridine synthase activity
NRBB56_RS02860	COG1609	Transcriptional regulator
NRBB56_RS02870	COG1175	transmembrane transport
NRBB56_RS02875	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS02885	COG1653	transport
NRBB56_RS02905	COG0601	transmembrane transport
NRBB56_RS02910	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRBB56_RS02920	COG4608	Belongs to the ABC transporter superfamily
NRBB56_RS02930	COG0626	cystathionine gamma-synthase activity
NRBB56_RS02935	COG0514	ATP-dependent DNA helicase (RecQ)
NRBB56_RS02950	COG0531	amino acid
NRBB56_RS02955	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
NRBB56_RS02965	COG0358	DNA primase activity
NRBB56_RS02990	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRBB56_RS02995	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
NRBB56_RS03030	COG1609	Transcriptional regulator
NRBB56_RS03035	COG0366	Alpha amylase catalytic
NRBB56_RS03070	COG1136	(ABC) transporter
NRBB56_RS03070	COG0577	efflux transmembrane transporter activity
NRBB56_RS03080	COG0577	efflux transmembrane transporter activity
NRBB56_RS03080	COG0577	efflux transmembrane transporter activity
NRBB56_RS03085	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
NRBB56_RS03090	COG0604	alcohol dehydrogenase
NRBB56_RS03095	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
NRBB56_RS03100	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
NRBB56_RS03145	COG0701	Predicted permease
NRBB56_RS03175	COG1012	belongs to the aldehyde dehydrogenase family
NRBB56_RS03195	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRBB56_RS03260	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
NRBB56_RS03275	COG0436	Aminotransferase
NRBB56_RS03295	COG0385	Bile acid
NRBB56_RS03330	COG0583	DNA-binding transcription factor activity
NRBB56_RS03365	COG1063	alcohol dehydrogenase
NRBB56_RS03395	COG1175	transmembrane transport
NRBB56_RS03415	COG0583	DNA-binding transcription factor activity
NRBB56_RS03425	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRBB56_RS03450	COG0110	maltose O-acetyltransferase activity
NRBB56_RS03455	COG0110	maltose O-acetyltransferase activity
NRBB56_RS03480	COG2199	diguanylate cyclase activity
NRBB56_RS03485	COG0390	transport system, permease component
NRBB56_RS03490	COG1132	(ABC) transporter
NRBB56_RS03515	COG0284	orotidine-5'-phosphate decarboxylase activity
NRBB56_RS03525	COG2176	DNA-directed DNA polymerase activity
NRBB56_RS03545	COG0626	cystathionine gamma-synthase activity
NRBB56_RS03595	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
NRBB56_RS03675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
NRBB56_RS03690	COG1122	ATPase activity
NRBB56_RS03730	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRBB56_RS03740	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRBB56_RS03745	COG4721	ABC-type cobalt transport system, permease component
NRBB56_RS03750	COG1122	ATPase activity
NRBB56_RS03760	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRBB56_RS03815	COG1116	anion transmembrane transporter activity
NRBB56_RS03825	COG4115	mRNA cleavage
NRBB56_RS03855	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
NRBB56_RS03860	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
NRBB56_RS03920	COG0497	DNA recombination
NRBB56_RS03925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRBB56_RS03975	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
NRBB56_RS03980	COG1472	Belongs to the glycosyl hydrolase 3 family
NRBB56_RS03995	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
NRBB56_RS03995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRBB56_RS04010	COG0667	Aldo Keto reductase
NRBB56_RS04045	COG1760	l-serine dehydratase
NRBB56_RS04055	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
NRBB56_RS04080	COG1316	TRANSCRIPTIONal
NRBB56_RS04120	COG2205	protein histidine kinase activity
NRBB56_RS04125	COG0745	RESPONSE REGULATOR receiver
NRBB56_RS04145	COG1108	ABC-type Mn2 Zn2 transport systems permease components
NRBB56_RS04150	COG1121	(ABC) transporter
NRBB56_RS04165	COG0539	negative regulation of cytoplasmic translation
NRBB56_RS04185	COG0469	pyruvate kinase activity
NRBB56_RS04190	COG0494	nUDIX hydrolase
NRBB56_RS04210	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
NRBB56_RS04215	COG1051	belongs to the nudix hydrolase family
NRBB56_RS04300	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
NRBB56_RS04305	COG0857	belongs to the CobB CobQ family
NRBB56_RS04305	COG0280	phosphate acetyltransferase
NRBB56_RS04345	COG0799	negative regulation of ribosome biogenesis
NRBB56_RS04350	COG0406	alpha-ribazole phosphatase activity
NRBB56_RS04380	COG2011	ABC-type metal ion transport system permease component
NRBB56_RS04400	COG1882	Formate acetyltransferase
NRBB56_RS04460	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
NRBB56_RS04465	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
NRBB56_RS04470	COG1611	Belongs to the LOG family
NRBB56_RS04485	COG1053	succinate dehydrogenase
NRBB56_RS04490	COG0758	DNA mediated transformation
NRBB56_RS04520	COG2873	o-acetylhomoserine
NRBB56_RS04525	COG1136	(ABC) transporter
NRBB56_RS04530	COG1136	(ABC) transporter
NRBB56_RS04530	COG0577	efflux transmembrane transporter activity
NRBB56_RS04535	COG2197	response regulator
NRBB56_RS04550	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
NRBB56_RS04555	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB56_RS04560	COG1126	abc transporter atp-binding protein
NRBB56_RS04565	COG0765	amino acid transport
NRBB56_RS04570	COG0765	amino acid transport
NRBB56_RS04575	COG0012	GTP binding
NRBB56_RS04600	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
NRBB56_RS04615	COG3177	Filamentation induced by cAMP protein fic
NRBB56_RS04665	COG1309	transcriptional regulator
NRBB56_RS04750	COG2814	Major facilitator Superfamily
NRBB56_RS04760	COG2815	serine threonine protein kinase
NRBB56_RS04760	COG0515	serine threonine protein kinase
NRBB56_RS04820	COG1940	carbohydrate kinase activity
NRBB56_RS04820	COG1846	Transcriptional regulator
NRBB56_RS04835	COG0477	Major facilitator Superfamily
NRBB56_RS04840	COG3119	arylsulfatase activity
NRBB56_RS04845	COG0641	radical SAM
NRBB56_RS04850	COG0730	response to heat
NRBB56_RS04875	COG0477	Major facilitator Superfamily
NRBB56_RS04895	COG2977	Belongs to the P-Pant transferase superfamily
NRBB56_RS04945	COG2233	PERMEase
NRBB56_RS04950	COG0513	Belongs to the DEAD box helicase family
NRBB56_RS04955	COG0366	Alpha amylase catalytic
NRBB56_RS04960	COG0306	phosphate transporter
NRBB56_RS04970	COG2197	response regulator
NRBB56_RS04975	COG4585	Histidine kinase
NRBB56_RS04980	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRBB56_RS04985	COG1131	(ABC) transporter
NRBB56_RS05015	COG3340	Belongs to the peptidase S51 family
NRBB56_RS05020	COG1335	isochorismatase
NRBB56_RS05040	COG3655	Transcriptional regulator
NRBB56_RS05070	COG0577	efflux transmembrane transporter activity
NRBB56_RS05070	COG1136	(ABC) transporter
NRBB56_RS05080	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
NRBB56_RS05160	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
NRBB56_RS05185	COG0719	Fe-S assembly protein
NRBB56_RS05190	COG0396	ATPase activity
NRBB56_RS05195	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
NRBB56_RS05205	COG2151	metal-sulfur cluster biosynthetic enzyme
NRBB56_RS05225	COG1385	rRNA (uridine-N3-)-methyltransferase activity
NRBB56_RS05230	COG0537	adenosine 5'-monophosphoramidase activity
NRBB56_RS05255	COG1022	Amp-dependent synthetase and ligase
NRBB56_RS05260	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
NRBB56_RS05285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
NRBB56_RS05295	COG2860	membrane
NRBB56_RS05335	COG0069	glutamate synthase activity
NRBB56_RS05335	COG0070	glutamate synthase
NRBB56_RS05335	COG0067	glutamate synthase
NRBB56_RS05345	COG4166	transmembrane transport
NRBB56_RS05360	COG0297	glycogen (starch) synthase activity
NRBB56_RS05365	COG1119	ATPase activity
NRBB56_RS05370	COG0561	phosphatase activity
NRBB56_RS05370	COG0561	phosphatase activity
NRBB56_RS05400	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
NRBB56_RS05410	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
NRBB56_RS05430	COG0588	phosphoglycerate mutase activity
NRBB56_RS05440	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
NRBB56_RS05465	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
NRBB56_RS05470	COG0284	orotidine-5'-phosphate decarboxylase activity
NRBB56_RS05475	COG0543	2 iron, 2 sulfur cluster binding
NRBB56_RS05480	COG0167	dihydroorotate dehydrogenase activity
NRBB56_RS05500	COG0583	DNA-binding transcription factor activity
NRBB56_RS05515	COG0488	(ABC) transporter
NRBB56_RS05520	COG4221	oxidoreductase activity
NRBB56_RS05555	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
NRBB56_RS05580	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
NRBB56_RS05595	COG0436	Aminotransferase
NRBB56_RS05625	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
NRBB56_RS05725	COG0045	succinate-CoA ligase (ADP-forming) activity
NRBB56_RS05750	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
NRBB56_RS05755	COG1187	pseudouridine synthase activity
NRBB56_RS05820	COG1716	ATPase activity
NRBB56_RS05855	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRBB56_RS05870	COG0133	tryptophan synthase activity
NRBB56_RS05875	COG2135	peptidase activity
NRBB56_RS05885	COG0833	amino acid
NRBB56_RS05975	COG4181	ATPase activity
NRBB56_RS06020	COG1131	(ABC) transporter
NRBB56_RS06050	COG1131	(ABC) transporter
NRBB56_RS06060	COG2197	response regulator
NRBB56_RS06065	COG4585	Histidine kinase
NRBB56_RS06075	COG1136	(ABC) transporter
NRBB56_RS06075	COG0577	efflux transmembrane transporter activity
NRBB56_RS06125	COG0833	amino acid
NRBB56_RS06135	COG3189	MarR family transcriptional regulator
NRBB56_RS06170	COG0693	protein deglycase activity
NRBB56_RS06180	COG0575	Belongs to the CDS family
NRBB56_RS06220	COG0516	GMP reductase activity
NRBB56_RS06330	COG0456	acetyltransferase
NRBB56_RS06340	COG0802	atpase or kinase
NRBB56_RS06365	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB56_RS06370	COG0598	Magnesium transport protein CorA
NRBB56_RS06375	COG0406	alpha-ribazole phosphatase activity
NRBB56_RS06405	COG4974	Belongs to the 'phage' integrase family
NRBB56_RS06430	COG0551	DNA topoisomerase type I activity
NRBB56_RS06430	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
NRBB56_RS06470	COG3843	relaxase mobilization nuclease domain protein
NRBB56_RS06530	COG3942	CHAP domain
NRBB56_RS06530	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRBB56_RS06630	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
NRBB56_RS06655	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
NRBB56_RS06670	COG1201	RNA secondary structure unwinding
NRBB56_RS06675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRBB56_RS06685	COG0187	DNA topoisomerase II activity
NRBB56_RS06690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
NRBB56_RS06700	COG0142	geranyltranstransferase activity
NRBB56_RS06720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
NRBB56_RS06730	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
NRBB56_RS06755	COG1396	sequence-specific DNA binding
NRBB56_RS06760	COG1546	Belongs to the CinA family
NRBB56_RS06760	COG1058	Belongs to the CinA family
NRBB56_RS06790	COG2357	RelA SpoT domain protein
NRBB56_RS06830	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRBB56_RS06855	COG0708	Exodeoxyribonuclease III
NRBB56_RS06865	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
NRBB56_RS06870	COG0601	transmembrane transport
NRBB56_RS06875	COG4166	transmembrane transport
NRBB56_RS06885	COG0577	efflux transmembrane transporter activity
NRBB56_RS06885	COG1136	(ABC) transporter
NRBB56_RS06890	COG0577	efflux transmembrane transporter activity
NRBB56_RS06900	COG0287	Prephenate dehydrogenase
NRBB56_RS06915	COG1217	gtp-binding protein TYPA
NRBB56_RS06925	COG1136	(ABC) transporter
NRBB56_RS06925	COG4591	ABC-type transport system involved in lipoprotein release permease component
NRBB56_RS06935	COG0477	Major facilitator Superfamily
NRBB56_RS06950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
NRBB56_RS06955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
NRBB56_RS06965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
NRBB56_RS06970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
NRBB56_RS06985	COG1929	Belongs to the glycerate kinase type-1 family
NRBB56_RS07000	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
NRBB56_RS07020	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
NRBB56_RS07030	COG2017	converts alpha-aldose to the beta-anomer
NRBB56_RS07035	COG2017	converts alpha-aldose to the beta-anomer
NRBB56_RS07045	COG1595	DNA-templated transcription, initiation
NRBB56_RS07065	COG1196	nuclear chromosome segregation
NRBB56_RS07070	COG0285	dihydrofolate synthase activity
NRBB56_RS07075	COG0006	proline dipeptidase activity
NRBB56_RS07095	COG1940	carbohydrate kinase activity
NRBB56_RS07100	COG1940	carbohydrate kinase activity
NRBB56_RS07115	COG0738	Major facilitator superfamily
NRBB56_RS07160	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
NRBB56_RS07170	COG0768	penicillin binding
NRBB56_RS07195	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRBB56_RS07225	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
NRBB56_RS07235	COG1643	Atp-dependent helicase
NRBB56_RS07240	COG2814	Major facilitator Superfamily
NRBB56_RS07290	COG0656	L-ascorbic acid biosynthetic process
NRBB56_RS07300	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB56_RS07350	COG4716	Myosin-crossreactive antigen
NRBB56_RS07365	COG0587	DNA-directed DNA polymerase activity
NRBB56_RS07405	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
NRBB56_RS07430	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRBB56_RS07435	COG0352	thiamine-phosphate diphosphorylase activity
NRBB56_RS07435	COG0351	phosphomethylpyrimidine kinase
NRBB56_RS07450	COG2271	Major facilitator Superfamily
NRBB56_RS07460	COG2197	response regulator
NRBB56_RS07530	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRBB56_RS07535	COG2814	Major facilitator Superfamily
NRBB56_RS07550	COG4581	dead DEAH box helicase
NRBB56_RS07555	COG2326	polyphosphate kinase activity
NRBB56_RS07560	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
NRBB56_RS07565	COG1279	arginine transmembrane transporter activity
NRBB56_RS07575	COG0765	amino acid transport
NRBB56_RS07580	COG0765	amino acid transport
NRBB56_RS07585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
NRBB56_RS07590	COG1126	abc transporter atp-binding protein
NRBB56_RS07610	COG1196	nuclear chromosome segregation
NRBB56_RS07625	COG0477	Major facilitator Superfamily
NRBB56_RS07640	COG0402	S-adenosylhomocysteine deaminase activity
NRBB56_RS07650	COG0589	response to stress
NRBB56_RS07660	COG1278	Cold shock
NRBB56_RS07665	COG2205	protein histidine kinase activity
NRBB56_RS07670	COG0745	RESPONSE REGULATOR receiver
NRBB56_RS07690	COG1278	Cold shock
NRBB56_RS07705	COG0714	Associated with various cellular activities
NRBB56_RS07750	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
NRBB56_RS07780	COG4122	O-methyltransferase activity
NRBB56_RS07785	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
NRBB56_RS07790	COG1011	Hydrolase
NRBB56_RS07800	COG0586	Pfam SNARE associated Golgi protein
NRBB56_RS07805	COG0560	Phosphoserine phosphatase
NRBB56_RS07810	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
NRBB56_RS07850	COG1484	DNA-dependent DNA replication
NRBB56_RS07885	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
NRBB56_RS07890	COG1518	maintenance of DNA repeat elements
NRBB56_RS07950	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
NRBB56_RS07955	COG3069	C4-dicarboxylate transmembrane transporter activity
NRBB56_RS07975	COG1132	(ABC) transporter
NRBB56_RS07980	COG1132	(ABC) transporter
NRBB56_RS08030	COG1309	transcriptional regulator
NRBB56_RS08045	COG0602	queuosine metabolic process
NRBB56_RS08050	COG1328	CTP reductase activity
NRBB56_RS08050	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
NRBB56_RS08055	COG1570	exodeoxyribonuclease VII activity
NRBB56_RS08060	COG1722	exodeoxyribonuclease VII activity
NRBB56_RS08065	COG2249	NAD(P)H dehydrogenase (quinone) activity
NRBB56_RS08070	COG1022	Amp-dependent synthetase and ligase
NRBB56_RS08075	COG1970	mechanosensitive ion channel activity
NRBB56_RS08095	COG0248	Ppx GppA phosphatase
NRBB56_RS08100	COG0436	Aminotransferase
NRBB56_RS08170	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
NRBB56_RS08185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
NRBB56_RS08190	COG0009	L-threonylcarbamoyladenylate synthase
NRBB56_RS08250	COG0242	peptide deformylase activity
NRBB56_RS08270	COG1940	carbohydrate kinase activity
NRBB56_RS08295	COG1946	Acyl-CoA thioesterase
NRBB56_RS08305	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
NRBB56_RS08320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
NRBB56_RS08325	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
NRBB56_RS08350	COG1215	transferase activity, transferring glycosyl groups
NRBB56_RS08360	COG0463	Glycosyl transferase, family 2
NRBB56_RS08365	COG1454	alcohol dehydrogenase
NRBB56_RS08370	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
NRBB56_RS08415	COG0488	(ABC) transporter
NRBB56_RS08505	COG0758	DNA mediated transformation
NRBB56_RS08520	COG1126	abc transporter atp-binding protein
NRBB56_RS08570	COG3843	relaxase mobilization nuclease domain protein
NRBB56_RS08590	COG1475	DNA binding
NRBB56_RS08630	COG3250	beta-galactosidase activity
NRBB56_RS08640	COG1609	Transcriptional regulator
NRBB56_RS08675	COG0577	efflux transmembrane transporter activity
NRBB56_RS08695	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
NRBB56_RS08715	COG0589	response to stress
NRBB56_RS08720	COG3103	Sh3 type 3 domain protein
NRBB56_RS08720	COG1388	LysM domain
NRBB56_RS08720	COG0791	NLP P60 protein
NRBB56_RS08730	COG1705	Flagellar rod assembly protein muramidase FlgJ
NRBB56_RS08730	COG3942	CHAP domain
NRBB56_RS08735	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
NRBB56_RS08745	COG5002	protein histidine kinase activity
NRBB56_RS08760	COG1575	Belongs to the MenA family. Type 1 subfamily
NRBB56_RS08765	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
NRBB56_RS08775	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS08780	COG2814	Major facilitator Superfamily
NRBB56_RS08815	COG2197	response regulator
NRBB56_RS08835	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS08840	COG1175	transmembrane transport
NRBB56_RS08860	COG1597	lipid kinase activity
NRBB56_RS08860	COG1803	Methylglyoxal synthase
NRBB56_RS08890	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
NRBB56_RS08895	COG0328	RNA-DNA hybrid ribonuclease activity
NRBB56_RS08950	COG1609	Transcriptional regulator
NRBB56_RS08965	COG2308	Evidence 4 Homologs of previously reported genes of
NRBB56_RS09070	COG0255	Belongs to the universal ribosomal protein uL29 family
NRBB56_RS09120	COG3527	Alpha-acetolactate decarboxylase
NRBB56_RS09130	COG1454	alcohol dehydrogenase
NRBB56_RS09130	COG1012	belongs to the aldehyde dehydrogenase family
NRBB56_RS09170	COG1739	Uncharacterized protein family UPF0029
NRBB56_RS09175	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
NRBB56_RS09185	COG2723	6-phospho-beta-galactosidase activity
NRBB56_RS09195	COG1175	transmembrane transport
NRBB56_RS09205	COG1609	Transcriptional regulator
NRBB56_RS09220	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
NRBB56_RS09235	COG0531	amino acid
NRBB56_RS09240	COG0812	UDP-N-acetylmuramate dehydrogenase activity
NRBB56_RS09285	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
NRBB56_RS09335	COG2252	PERMEase
NRBB56_RS09360	COG0745	RESPONSE REGULATOR receiver
NRBB56_RS09365	COG5002	protein histidine kinase activity
NRBB56_RS09370	COG0477	Major facilitator Superfamily
NRBB56_RS09380	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRBB56_RS09385	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
NRBB56_RS09395	COG3250	beta-galactosidase activity
NRBB56_RS09400	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
NRBB56_RS09415	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS09420	COG1175	transmembrane transport
NRBB56_RS09425	COG1653	transport
NRBB56_RS09455	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
NRBB56_RS09470	COG0826	peptidase U32
NRBB56_RS09480	COG0742	ribosomal rna small subunit methyltransferase
NRBB56_RS09495	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
NRBB56_RS09495	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
NRBB56_RS09500	COG2270	Major facilitator Superfamily
NRBB56_RS09505	COG0789	Transcriptional regulator
NRBB56_RS09600	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
NRBB56_RS09605	COG4770	biotin carboxylase activity
NRBB56_RS09610	COG1268	BioY protein
NRBB56_RS09645	COG0250	Participates in transcription elongation, termination and antitermination
NRBB56_RS09660	COG0436	Aminotransferase
NRBB56_RS09690	COG1530	ribonuclease E activity
NRBB56_RS09695	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
NRBB56_RS09705	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
NRBB56_RS09730	COG4948	Mandelate Racemase Muconate Lactonizing
NRBB56_RS09735	COG1609	Transcriptional regulator
NRBB56_RS09765	COG0083	homoserine kinase activity
NRBB56_RS09770	COG0460	homoserine dehydrogenase
NRBB56_RS09775	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB56_RS09775	COG2190	(PTS) system
NRBB56_RS09775	COG1263	PTS System
NRBB56_RS09780	COG1263	PTS System
NRBB56_RS09780	COG2190	(PTS) system
NRBB56_RS09780	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB56_RS09795	COG1309	transcriptional regulator
NRBB56_RS09805	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
NRBB56_RS09810	COG0446	pyridine nucleotide-disulphide oxidoreductase
NRBB56_RS09820	COG0765	amino acid transport
NRBB56_RS09835	COG1126	abc transporter atp-binding protein
NRBB56_RS09840	COG0167	dihydroorotate dehydrogenase activity
NRBB56_RS09880	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
NRBB56_RS09885	COG0494	nUDIX hydrolase
NRBB56_RS09885	COG0406	alpha-ribazole phosphatase activity
NRBB56_RS09920	COG0584	glycerophosphoryl diester phosphodiesterase
NRBB56_RS09945	COG0179	Fumarylacetoacetate (FAA) hydrolase
NRBB56_RS09970	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB56_RS09975	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB56_RS09980	COG1129	ABC transporter
NRBB56_RS09990	COG1070	Carbohydrate kinase
NRBB56_RS10005	COG1442	glycosyl transferase family 8
NRBB56_RS10005	COG1216	Glycosyl transferase, family 2
NRBB56_RS10050	COG0463	Glycosyl transferase, family 2
NRBB56_RS10065	COG1088	dTDP-glucose 4,6-dehydratase activity
NRBB56_RS10080	COG3757	hydrolase, family 25
NRBB56_RS10080	COG3409	Peptidoglycan-binding domain 1 protein
NRBB56_RS10100	COG2801	Transposase and inactivated derivatives
NRBB56_RS10105	COG1316	TRANSCRIPTIONal
NRBB56_RS10110	COG0577	efflux transmembrane transporter activity
NRBB56_RS10115	COG1129	ABC transporter
NRBB56_RS10140	COG0084	hydrolase, TatD family'
NRBB56_RS10145	COG1132	(ABC) transporter
NRBB56_RS10150	COG1132	(ABC) transporter
NRBB56_RS10240	COG1846	Transcriptional regulator
NRBB56_RS10275	COG1609	Transcriptional regulator
NRBB56_RS10290	COG1172	Belongs to the binding-protein-dependent transport system permease family
NRBB56_RS10295	COG1129	ABC transporter
NRBB56_RS10340	COG3293	Transposase
NRBB56_RS10345	COG1113	amino acid transport
NRBB56_RS10355	COG0577	efflux transmembrane transporter activity
NRBB56_RS10355	COG1136	(ABC) transporter
NRBB56_RS10360	COG1113	amino acid transport
NRBB56_RS10380	COG1609	Transcriptional regulator
NRBB56_RS10385	COG2182	Extracellular solute-binding protein
NRBB56_RS10390	COG0588	phosphoglycerate mutase activity
NRBB56_RS10440	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
NRBB56_RS10445	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
NRBB56_RS10450	COG0366	Alpha amylase catalytic
NRBB56_RS10460	COG0366	Alpha amylase catalytic
NRBB56_RS10465	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS10495	COG1609	Transcriptional regulator
NRBB56_RS10500	COG1609	Transcriptional regulator
NRBB56_RS10505	COG0395	ABC-type sugar transport system, permease component
NRBB56_RS10510	COG1175	transmembrane transport
NRBB56_RS10535	COG0590	tRNA wobble adenosine to inosine editing
NRBB56_RS10535	COG0037	tRNA processing
NRBB56_RS10540	COG0025	NhaP-type Na H and K H
NRBB56_RS10545	COG0730	response to heat
NRBB56_RS10570	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
NRBB56_RS10580	COG2190	(PTS) system
NRBB56_RS10580	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
NRBB56_RS10580	COG1263	PTS System
NRBB56_RS10595	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
NRBB56_RS10635	COG3842	ATPase activity
NRBB56_RS10640	COG2188	Transcriptional regulator
NRBB56_RS10655	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
NRBB56_RS10660	COG1215	transferase activity, transferring glycosyl groups
NRBB56_RS10680	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
NRBB56_RS10705	COG1472	Belongs to the glycosyl hydrolase 3 family
NRBB56_RS10720	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
NRBB56_RS10725	COG1472	Belongs to the glycosyl hydrolase 3 family
NRBB56_RS10745	COG3583	domain protein
NRBB56_RS10765	COG0617	tRNA 3'-terminal CCA addition
NRBB56_RS10785	COG0492	ferredoxin-NADP+ reductase activity
NRBB56_RS10790	COG1475	DNA binding
NRBB56_RS10795	COG1192	Involved in chromosome partitioning
NRBB56_RS10805	COG1847	R3H domain protein