locus-tag	class	description
BBR_RS10260	COG0592	DNA-directed DNA polymerase activity
BBR_RS10275	COG0187	DNA topoisomerase II activity
BBR_RS10280	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBR_RS10290	COG1609	Transcriptional regulator
BBR_RS10300	COG3250	beta-galactosidase activity
BBR_RS10310	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BBR_RS10345	COG0783	Belongs to the Dps family
BBR_RS10365	COG1609	Transcriptional regulator
BBR_RS10385	COG1609	Transcriptional regulator
BBR_RS10430	COG1609	Transcriptional regulator
BBR_RS10440	COG0783	Belongs to the Dps family
BBR_RS10445	COG1253	flavin adenine dinucleotide binding
BBR_RS10510	COG4251	negative regulation of phosphorylation
BBR_RS10510	COG5001	Diguanylate cyclase
BBR_RS10510	COG3706	GGDEF domain
BBR_RS10510	COG2203	Gaf domain
BBR_RS10525	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BBR_RS10535	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BBR_RS10550	COG0180	Tryptophanyl-tRNA synthetase
BBR_RS10565	COG0058	SHG alpha-glucan phosphorylase activity
BBR_RS10605	COG0515	serine threonine protein kinase
BBR_RS10610	COG0768	penicillin binding
BBR_RS10645	COG0071	Belongs to the small heat shock protein (HSP20) family
BBR_RS10650	COG0697	spore germination
BBR_RS10660	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BBR_RS10665	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BBR_RS10695	COG0494	nUDIX hydrolase
BBR_RS10715	COG0343	queuine tRNA-ribosyltransferase activity
BBR_RS10745	COG0697	spore germination
BBR_RS10750	COG0191	fructose-bisphosphate aldolase activity
BBR_RS10790	COG1609	Transcriptional regulator
BBR_RS10795	COG0477	Major facilitator Superfamily
BBR_RS10820	COG0395	ABC-type sugar transport system, permease component
BBR_RS10835	COG0366	Alpha amylase catalytic
BBR_RS10840	COG1609	Transcriptional regulator
BBR_RS10875	COG1175	transmembrane transport
BBR_RS10880	COG3833	ABC-type maltose transport systems, permease component
BBR_RS10895	COG1523	belongs to the glycosyl hydrolase 13 family
BBR_RS10915	COG0789	Transcriptional regulator
BBR_RS10930	COG1028	Short-chain dehydrogenase reductase Sdr
BBR_RS10935	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBR_RS10940	COG0586	Pfam SNARE associated Golgi protein
BBR_RS10980	COG1309	transcriptional regulator
BBR_RS11020	COG0527	aspartate kinase activity
BBR_RS11055	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BBR_RS11060	COG1176	ABC-type spermidine putrescine transport system, permease component I
BBR_RS11070	COG3842	ATPase activity
BBR_RS11100	COG1940	carbohydrate kinase activity
BBR_RS11105	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BBR_RS11115	COG0747	negative chemotaxis
BBR_RS11125	COG0444	Belongs to the ABC transporter superfamily
BBR_RS11130	COG4608	Belongs to the ABC transporter superfamily
BBR_RS11135	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBR_RS11160	COG2186	Transcriptional regulator
BBR_RS11185	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BBR_RS11185	COG1754	DNA topoisomerase type I activity
BBR_RS11195	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BBR_RS11210	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BBR_RS11290	COG3619	membrane
BBR_RS11295	COG1733	regulation of RNA biosynthetic process
BBR_RS11300	COG2910	NAD(P)H-binding
BBR_RS11315	COG0477	Major facilitator Superfamily
BBR_RS11320	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BBR_RS11325	COG0604	alcohol dehydrogenase
BBR_RS11325	COG3321	synthase
BBR_RS11325	COG1028	Short-chain dehydrogenase reductase Sdr
BBR_RS11345	COG2977	Belongs to the P-Pant transferase superfamily
BBR_RS11370	COG2801	Transposase and inactivated derivatives
BBR_RS11410	COG0672	)-iron permease
BBR_RS11415	COG3470	protein probably involved in high-affinity Fe2 transport
BBR_RS11425	COG0577	efflux transmembrane transporter activity
BBR_RS11430	COG0577	efflux transmembrane transporter activity
BBR_RS11435	COG1136	(ABC) transporter
BBR_RS11465	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BBR_RS11470	COG0363	glucosamine-6-phosphate deaminase activity
BBR_RS11500	COG1442	glycosyl transferase family 8
BBR_RS11500	COG1216	Glycosyl transferase, family 2
BBR_RS11505	COG1309	transcriptional regulator
BBR_RS11525	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BBR_RS11535	COG0305	Participates in initiation and elongation during chromosome replication
BBR_RS11540	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBR_RS11545	COG3442	glutamine amidotransferase
BBR_RS11570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BBR_RS11610	COG1131	(ABC) transporter
BBR_RS11655	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBR_RS11665	COG1937	Protein conserved in bacteria
BBR_RS11685	COG1131	(ABC) transporter
BBR_RS11740	COG2211	Major facilitator Superfamily
BBR_RS11760	COG4974	Belongs to the 'phage' integrase family
BBR_RS11765	COG2801	Transposase and inactivated derivatives
BBR_RS11795	COG0745	RESPONSE REGULATOR receiver
BBR_RS11810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BBR_RS11865	COG2826	transposase and inactivated derivatives, IS30 family
BBR_RS11870	COG4209	transmembrane transport
BBR_RS11875	COG0395	ABC-type sugar transport system, permease component
BBR_RS11905	COG3250	beta-galactosidase activity
BBR_RS11980	COG4974	Belongs to the 'phage' integrase family
BBR_RS11995	COG0356	it plays a direct role in the translocation of protons across the membrane
BBR_RS12030	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BBR_RS12070	COG0251	oxidation-reduction process
BBR_RS12105	COG3842	ATPase activity
BBR_RS12120	COG1027	Aspartate ammonia-lyase
BBR_RS12130	COG0730	response to heat
BBR_RS12135	COG0641	radical SAM
BBR_RS12140	COG1609	Transcriptional regulator
BBR_RS12145	COG3119	arylsulfatase activity
BBR_RS12160	COG0395	ABC-type sugar transport system, permease component
BBR_RS12165	COG1373	ATPase (AAA superfamily
BBR_RS12170	COG3328	transposase activity
BBR_RS12185	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BBR_RS12200	COG0475	glutathione-regulated potassium exporter activity
BBR_RS12200	COG0569	domain protein
BBR_RS12250	COG1136	(ABC) transporter
BBR_RS12260	COG1704	LemA family
BBR_RS12295	COG1837	Belongs to the UPF0109 family
BBR_RS12325	COG0519	Catalyzes the synthesis of GMP from XMP
BBR_RS12330	COG0488	(ABC) transporter
BBR_RS12335	COG1487	ribonuclease activity
BBR_RS12345	COG0440	acetolactate synthase activity
BBR_RS12385	COG0667	Aldo Keto reductase
BBR_RS12435	COG1116	anion transmembrane transporter activity
BBR_RS12455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BBR_RS12460	COG1609	Transcriptional regulator
BBR_RS12475	COG2814	Major facilitator Superfamily
BBR_RS12475	COG0477	Major facilitator Superfamily
BBR_RS12485	COG4988	ABC transporter
BBR_RS12495	COG1653	transport
BBR_RS12500	COG1175	transmembrane transport
BBR_RS12505	COG0395	ABC-type sugar transport system, permease component
BBR_RS12520	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BBR_RS12525	COG0656	L-ascorbic acid biosynthetic process
BBR_RS12540	COG2814	Major facilitator Superfamily
BBR_RS12555	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBR_RS12600	COG1045	serine acetyltransferase
BBR_RS12605	COG1215	transferase activity, transferring glycosyl groups
BBR_RS12620	COG0438	transferase activity, transferring glycosyl groups
BBR_RS12625	COG0438	transferase activity, transferring glycosyl groups
BBR_RS12640	COG1442	glycosyl transferase family 8
BBR_RS12640	COG1216	Glycosyl transferase, family 2
BBR_RS12645	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BBR_RS12655	COG1216	Glycosyl transferase, family 2
BBR_RS12675	COG1484	DNA-dependent DNA replication
BBR_RS12820	COG0489	protein tyrosine kinase activity
BBR_RS12875	COG0095	Lipoate-protein ligase
BBR_RS12880	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBR_RS12885	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BBR_RS12885	COG4499	WXG100 protein secretion system (Wss), protein YukC
BBR_RS12890	COG1902	pentaerythritol trinitrate reductase activity
BBR_RS12895	COG0167	dihydroorotate dehydrogenase activity
BBR_RS12900	COG1349	DNA-binding transcription factor activity
BBR_RS12910	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BBR_RS12930	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BBR_RS12965	COG0714	Associated with various cellular activities
BBR_RS12980	COG0210	DNA helicase
BBR_RS13000	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BBR_RS13025	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BBR_RS13030	COG2884	Cell division ATP-binding protein ftsE
BBR_RS13035	COG2177	Part of the ABC transporter FtsEX involved in
BBR_RS13040	COG1388	LysM domain
BBR_RS13040	COG3942	CHAP domain
BBR_RS13065	COG1126	abc transporter atp-binding protein
BBR_RS13075	COG0564	pseudouridine synthase activity
BBR_RS13080	COG1609	Transcriptional regulator
BBR_RS13085	COG1175	transmembrane transport
BBR_RS13090	COG0395	ABC-type sugar transport system, permease component
BBR_RS13100	COG1653	transport
BBR_RS13115	COG4166	transmembrane transport
BBR_RS13120	COG0601	transmembrane transport
BBR_RS13125	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBR_RS13135	COG4608	Belongs to the ABC transporter superfamily
BBR_RS13145	COG0626	cystathionine gamma-synthase activity
BBR_RS13150	COG0514	ATP-dependent DNA helicase (RecQ)
BBR_RS13165	COG0531	amino acid
BBR_RS13170	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BBR_RS13180	COG0358	DNA primase activity
BBR_RS13205	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBR_RS13210	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BBR_RS13245	COG1609	Transcriptional regulator
BBR_RS13250	COG0366	Alpha amylase catalytic
BBR_RS13270	COG0577	efflux transmembrane transporter activity
BBR_RS13270	COG1136	(ABC) transporter
BBR_RS13280	COG0577	efflux transmembrane transporter activity
BBR_RS13280	COG0577	efflux transmembrane transporter activity
BBR_RS13285	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BBR_RS13290	COG0604	alcohol dehydrogenase
BBR_RS13295	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BBR_RS13300	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BBR_RS13345	COG0701	Predicted permease
BBR_RS13365	COG1012	belongs to the aldehyde dehydrogenase family
BBR_RS13385	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBR_RS13445	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BBR_RS13460	COG0436	Aminotransferase
BBR_RS13480	COG0385	Bile acid
BBR_RS13510	COG0583	DNA-binding transcription factor activity
BBR_RS13540	COG1063	alcohol dehydrogenase
BBR_RS13550	COG1392	Phosphate transport regulator
BBR_RS13555	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBR_RS13575	COG0110	maltose O-acetyltransferase activity
BBR_RS13605	COG2199	diguanylate cyclase activity
BBR_RS13610	COG0390	transport system, permease component
BBR_RS13615	COG1136	(ABC) transporter
BBR_RS13615	COG0577	efflux transmembrane transporter activity
BBR_RS13640	COG0284	orotidine-5'-phosphate decarboxylase activity
BBR_RS13650	COG2176	DNA-directed DNA polymerase activity
BBR_RS13670	COG0626	cystathionine gamma-synthase activity
BBR_RS13700	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BBR_RS13780	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BBR_RS13795	COG1122	ATPase activity
BBR_RS13835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBR_RS13845	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBR_RS13850	COG4721	ABC-type cobalt transport system, permease component
BBR_RS13855	COG1122	ATPase activity
BBR_RS13865	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBR_RS13945	COG4115	mRNA cleavage
BBR_RS13970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BBR_RS13975	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BBR_RS14020	COG0569	domain protein
BBR_RS14030	COG0497	DNA recombination
BBR_RS14035	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBR_RS14085	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BBR_RS14090	COG1472	Belongs to the glycosyl hydrolase 3 family
BBR_RS14105	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BBR_RS14105	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBR_RS14120	COG0667	Aldo Keto reductase
BBR_RS14155	COG1760	l-serine dehydratase
BBR_RS14165	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BBR_RS14190	COG1316	TRANSCRIPTIONal
BBR_RS14230	COG2205	protein histidine kinase activity
BBR_RS14235	COG0745	RESPONSE REGULATOR receiver
BBR_RS14255	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BBR_RS14260	COG1121	(ABC) transporter
BBR_RS14275	COG0539	negative regulation of cytoplasmic translation
BBR_RS14295	COG0469	pyruvate kinase activity
BBR_RS14300	COG0494	nUDIX hydrolase
BBR_RS14320	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BBR_RS14325	COG1051	belongs to the nudix hydrolase family
BBR_RS14350	COG0519	Catalyzes the synthesis of GMP from XMP
BBR_RS14375	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BBR_RS14380	COG0857	belongs to the CobB CobQ family
BBR_RS14380	COG0280	phosphate acetyltransferase
BBR_RS14420	COG0799	negative regulation of ribosome biogenesis
BBR_RS14425	COG0406	alpha-ribazole phosphatase activity
BBR_RS14455	COG2011	ABC-type metal ion transport system permease component
BBR_RS14460	COG1473	amidohydrolase
BBR_RS14475	COG1882	Formate acetyltransferase
BBR_RS14535	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BBR_RS14540	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BBR_RS14545	COG1611	Belongs to the LOG family
BBR_RS14560	COG1053	succinate dehydrogenase
BBR_RS14565	COG0758	DNA mediated transformation
BBR_RS14595	COG2873	o-acetylhomoserine
BBR_RS14600	COG1136	(ABC) transporter
BBR_RS14605	COG0577	efflux transmembrane transporter activity
BBR_RS14605	COG1136	(ABC) transporter
BBR_RS14610	COG2197	response regulator
BBR_RS14625	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BBR_RS14630	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBR_RS14635	COG1126	abc transporter atp-binding protein
BBR_RS14640	COG0765	amino acid transport
BBR_RS14645	COG0765	amino acid transport
BBR_RS14650	COG0012	GTP binding
BBR_RS14670	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BBR_RS14680	COG3177	Filamentation induced by cAMP protein fic
BBR_RS14735	COG1309	transcriptional regulator
BBR_RS14745	COG2814	Major facilitator Superfamily
BBR_RS14750	COG2815	serine threonine protein kinase
BBR_RS14750	COG0515	serine threonine protein kinase
BBR_RS14805	COG1940	carbohydrate kinase activity
BBR_RS14805	COG1846	Transcriptional regulator
BBR_RS14820	COG0477	Major facilitator Superfamily
BBR_RS14825	COG3119	arylsulfatase activity
BBR_RS14830	COG0641	radical SAM
BBR_RS14835	COG0730	response to heat
BBR_RS14875	COG2233	PERMEase
BBR_RS14880	COG0513	Belongs to the DEAD box helicase family
BBR_RS14885	COG0366	Alpha amylase catalytic
BBR_RS14890	COG0306	phosphate transporter
BBR_RS14900	COG2197	response regulator
BBR_RS14905	COG4585	Histidine kinase
BBR_RS14910	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBR_RS14915	COG1131	(ABC) transporter
BBR_RS14945	COG3340	Belongs to the peptidase S51 family
BBR_RS14950	COG1335	isochorismatase
BBR_RS14970	COG3655	Transcriptional regulator
BBR_RS15000	COG1136	(ABC) transporter
BBR_RS15000	COG0577	efflux transmembrane transporter activity
BBR_RS15010	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BBR_RS15090	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BBR_RS15110	COG0719	Fe-S assembly protein
BBR_RS15115	COG0396	ATPase activity
BBR_RS15120	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BBR_RS15130	COG2151	metal-sulfur cluster biosynthetic enzyme
BBR_RS15150	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BBR_RS15155	COG0537	adenosine 5'-monophosphoramidase activity
BBR_RS15180	COG1022	Amp-dependent synthetase and ligase
BBR_RS15185	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BBR_RS15210	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BBR_RS15220	COG2860	membrane
BBR_RS15255	COG0067	glutamate synthase
BBR_RS15255	COG0069	glutamate synthase activity
BBR_RS15255	COG0070	glutamate synthase
BBR_RS15270	COG4166	transmembrane transport
BBR_RS15285	COG0297	glycogen (starch) synthase activity
BBR_RS15290	COG1119	ATPase activity
BBR_RS15365	COG1073	alpha beta
BBR_RS15370	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BBR_RS15380	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BBR_RS15400	COG0588	phosphoglycerate mutase activity
BBR_RS15410	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BBR_RS15435	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BBR_RS15440	COG0284	orotidine-5'-phosphate decarboxylase activity
BBR_RS15445	COG0543	2 iron, 2 sulfur cluster binding
BBR_RS15450	COG0167	dihydroorotate dehydrogenase activity
BBR_RS15470	COG0583	DNA-binding transcription factor activity
BBR_RS15485	COG0488	(ABC) transporter
BBR_RS15490	COG4221	oxidoreductase activity
BBR_RS15495	COG1129	ABC transporter
BBR_RS15520	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BBR_RS15545	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBR_RS15560	COG0436	Aminotransferase
BBR_RS15575	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BBR_RS15675	COG0045	succinate-CoA ligase (ADP-forming) activity
BBR_RS15695	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BBR_RS15700	COG1187	pseudouridine synthase activity
BBR_RS15765	COG1716	ATPase activity
BBR_RS15800	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBR_RS15815	COG0133	tryptophan synthase activity
BBR_RS15820	COG2135	peptidase activity
BBR_RS15830	COG0833	amino acid
BBR_RS15905	COG4181	ATPase activity
BBR_RS15950	COG1131	(ABC) transporter
BBR_RS15980	COG1131	(ABC) transporter
BBR_RS15990	COG2197	response regulator
BBR_RS15995	COG4585	Histidine kinase
BBR_RS16005	COG1136	(ABC) transporter
BBR_RS16005	COG0577	efflux transmembrane transporter activity
BBR_RS16055	COG0833	amino acid
BBR_RS16065	COG3189	MarR family transcriptional regulator
BBR_RS16100	COG0693	protein deglycase activity
BBR_RS16110	COG0575	Belongs to the CDS family
BBR_RS16150	COG0516	GMP reductase activity
BBR_RS16245	COG0456	acetyltransferase
BBR_RS16255	COG0802	atpase or kinase
BBR_RS16280	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBR_RS16285	COG0598	Magnesium transport protein CorA
BBR_RS16290	COG0406	alpha-ribazole phosphatase activity
BBR_RS16350	COG0395	ABC-type sugar transport system, permease component
BBR_RS16355	COG1175	transmembrane transport
BBR_RS16410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BBR_RS16435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BBR_RS16460	COG1201	RNA secondary structure unwinding
BBR_RS16465	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBR_RS16475	COG0187	DNA topoisomerase II activity
BBR_RS16480	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BBR_RS16490	COG0142	geranyltranstransferase activity
BBR_RS16510	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BBR_RS16520	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BBR_RS16540	COG1396	sequence-specific DNA binding
BBR_RS16545	COG1058	Belongs to the CinA family
BBR_RS16545	COG1546	Belongs to the CinA family
BBR_RS16575	COG2357	RelA SpoT domain protein
BBR_RS16605	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBR_RS16630	COG0708	Exodeoxyribonuclease III
BBR_RS16640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BBR_RS16645	COG0601	transmembrane transport
BBR_RS16650	COG4166	transmembrane transport
BBR_RS16660	COG0577	efflux transmembrane transporter activity
BBR_RS16660	COG1136	(ABC) transporter
BBR_RS16665	COG0577	efflux transmembrane transporter activity
BBR_RS16675	COG0287	Prephenate dehydrogenase
BBR_RS16690	COG1217	gtp-binding protein TYPA
BBR_RS16700	COG1136	(ABC) transporter
BBR_RS16700	COG4591	ABC-type transport system involved in lipoprotein release permease component
BBR_RS16710	COG0477	Major facilitator Superfamily
BBR_RS16725	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BBR_RS16730	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BBR_RS16740	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BBR_RS16745	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BBR_RS16760	COG1929	Belongs to the glycerate kinase type-1 family
BBR_RS16775	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BBR_RS16795	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BBR_RS16805	COG2017	converts alpha-aldose to the beta-anomer
BBR_RS16810	COG2017	converts alpha-aldose to the beta-anomer
BBR_RS16820	COG1595	DNA-templated transcription, initiation
BBR_RS16840	COG1196	nuclear chromosome segregation
BBR_RS16845	COG0285	dihydrofolate synthase activity
BBR_RS16850	COG0006	proline dipeptidase activity
BBR_RS16870	COG1940	carbohydrate kinase activity
BBR_RS16875	COG1940	carbohydrate kinase activity
BBR_RS16895	COG0738	Major facilitator superfamily
BBR_RS16935	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BBR_RS16945	COG0768	penicillin binding
BBR_RS16970	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBR_RS17000	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BBR_RS17010	COG1643	Atp-dependent helicase
BBR_RS17015	COG2814	Major facilitator Superfamily
BBR_RS17065	COG0656	L-ascorbic acid biosynthetic process
BBR_RS17075	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBR_RS17110	COG4716	Myosin-crossreactive antigen
BBR_RS17125	COG0587	DNA-directed DNA polymerase activity
BBR_RS17160	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BBR_RS17180	COG1122	ATPase activity
BBR_RS17210	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBR_RS17215	COG0352	thiamine-phosphate diphosphorylase activity
BBR_RS17215	COG0351	phosphomethylpyrimidine kinase
BBR_RS17225	COG2271	Major facilitator Superfamily
BBR_RS17235	COG2197	response regulator
BBR_RS17310	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBR_RS17315	COG2814	Major facilitator Superfamily
BBR_RS17335	COG4581	dead DEAH box helicase
BBR_RS17340	COG2326	polyphosphate kinase activity
BBR_RS17345	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BBR_RS17350	COG1279	arginine transmembrane transporter activity
BBR_RS17360	COG0765	amino acid transport
BBR_RS17365	COG0765	amino acid transport
BBR_RS17370	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BBR_RS17375	COG1126	abc transporter atp-binding protein
BBR_RS17395	COG1196	nuclear chromosome segregation
BBR_RS17410	COG0477	Major facilitator Superfamily
BBR_RS17425	COG0402	S-adenosylhomocysteine deaminase activity
BBR_RS17435	COG0589	response to stress
BBR_RS17445	COG1278	Cold shock
BBR_RS17450	COG2205	protein histidine kinase activity
BBR_RS17455	COG0745	RESPONSE REGULATOR receiver
BBR_RS17475	COG1278	Cold shock
BBR_RS17490	COG0714	Associated with various cellular activities
BBR_RS17535	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BBR_RS17565	COG4122	O-methyltransferase activity
BBR_RS17570	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BBR_RS17580	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBR_RS17585	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBR_RS17585	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BBR_RS17585	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBR_RS17600	COG1011	Hydrolase
BBR_RS17610	COG0586	Pfam SNARE associated Golgi protein
BBR_RS17615	COG0560	Phosphoserine phosphatase
BBR_RS17620	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BBR_RS17690	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BBR_RS17695	COG1518	maintenance of DNA repeat elements
BBR_RS17750	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBR_RS17755	COG1869	D-ribose catabolic process
BBR_RS17765	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBR_RS17770	COG1129	ABC transporter
BBR_RS17790	COG1609	Transcriptional regulator
BBR_RS17800	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBR_RS17805	COG1979	alcohol dehydrogenase
BBR_RS17810	COG0546	phosphoglycolate phosphatase activity
BBR_RS17820	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BBR_RS17825	COG0135	phosphoribosylanthranilate isomerase activity
BBR_RS17830	COG1122	ATPase activity
BBR_RS17855	COG1132	(ABC) transporter
BBR_RS17860	COG1132	(ABC) transporter
BBR_RS17895	COG1309	transcriptional regulator
BBR_RS17910	COG0602	queuosine metabolic process
BBR_RS17915	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BBR_RS17915	COG1328	CTP reductase activity
BBR_RS17920	COG1570	exodeoxyribonuclease VII activity
BBR_RS17925	COG1722	exodeoxyribonuclease VII activity
BBR_RS17930	COG2249	NAD(P)H dehydrogenase (quinone) activity
BBR_RS17935	COG1022	Amp-dependent synthetase and ligase
BBR_RS17940	COG1970	mechanosensitive ion channel activity
BBR_RS17960	COG0248	Ppx GppA phosphatase
BBR_RS17965	COG0436	Aminotransferase
BBR_RS18030	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BBR_RS18045	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BBR_RS18050	COG0009	L-threonylcarbamoyladenylate synthase
BBR_RS18100	COG2814	Major facilitator Superfamily
BBR_RS18110	COG0242	peptide deformylase activity
BBR_RS18130	COG1940	carbohydrate kinase activity
BBR_RS18155	COG1946	Acyl-CoA thioesterase
BBR_RS18165	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BBR_RS18180	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BBR_RS18185	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BBR_RS18210	COG1215	transferase activity, transferring glycosyl groups
BBR_RS18220	COG0463	Glycosyl transferase, family 2
BBR_RS18225	COG1454	alcohol dehydrogenase
BBR_RS18230	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BBR_RS18275	COG1192	Involved in chromosome partitioning
BBR_RS18285	COG0488	(ABC) transporter
BBR_RS18355	COG3942	CHAP domain
BBR_RS18355	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBR_RS18365	COG0758	DNA mediated transformation
BBR_RS18380	COG1126	abc transporter atp-binding protein
BBR_RS18430	COG3843	relaxase mobilization nuclease domain protein
BBR_RS18450	COG1475	DNA binding
BBR_RS18475	COG3250	beta-galactosidase activity
BBR_RS18480	COG1609	Transcriptional regulator
BBR_RS18510	COG0577	efflux transmembrane transporter activity
BBR_RS18530	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BBR_RS18550	COG0589	response to stress
BBR_RS18555	COG3103	Sh3 type 3 domain protein
BBR_RS18555	COG1388	LysM domain
BBR_RS18555	COG0791	NLP P60 protein
BBR_RS18565	COG3942	CHAP domain
BBR_RS18565	COG1705	Flagellar rod assembly protein muramidase FlgJ
BBR_RS18580	COG5002	protein histidine kinase activity
BBR_RS18595	COG1575	Belongs to the MenA family. Type 1 subfamily
BBR_RS18600	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BBR_RS18610	COG2814	Major facilitator Superfamily
BBR_RS18645	COG2197	response regulator
BBR_RS18665	COG0395	ABC-type sugar transport system, permease component
BBR_RS18670	COG1175	transmembrane transport
BBR_RS18690	COG1597	lipid kinase activity
BBR_RS18690	COG1803	Methylglyoxal synthase
BBR_RS18720	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BBR_RS18725	COG0328	RNA-DNA hybrid ribonuclease activity
BBR_RS18745	COG0196	riboflavin kinase activity
BBR_RS18775	COG1609	Transcriptional regulator
BBR_RS18790	COG2308	Evidence 4 Homologs of previously reported genes of
BBR_RS18895	COG0255	Belongs to the universal ribosomal protein uL29 family
BBR_RS18945	COG3527	Alpha-acetolactate decarboxylase
BBR_RS18955	COG1012	belongs to the aldehyde dehydrogenase family
BBR_RS18955	COG1454	alcohol dehydrogenase
BBR_RS18995	COG1739	Uncharacterized protein family UPF0029
BBR_RS19000	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BBR_RS19010	COG2723	6-phospho-beta-galactosidase activity
BBR_RS19020	COG1175	transmembrane transport
BBR_RS19030	COG1609	Transcriptional regulator
BBR_RS19045	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BBR_RS19060	COG0531	amino acid
BBR_RS19065	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BBR_RS19145	COG2252	PERMEase
BBR_RS19170	COG0745	RESPONSE REGULATOR receiver
BBR_RS19175	COG5002	protein histidine kinase activity
BBR_RS19180	COG0477	Major facilitator Superfamily
BBR_RS19190	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBR_RS19195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BBR_RS19205	COG3250	beta-galactosidase activity
BBR_RS19210	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BBR_RS19225	COG0395	ABC-type sugar transport system, permease component
BBR_RS19230	COG1175	transmembrane transport
BBR_RS19235	COG1653	transport
BBR_RS19250	COG3579	cysteine-type endopeptidase activity
BBR_RS19265	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BBR_RS19280	COG0826	peptidase U32
BBR_RS19290	COG0742	ribosomal rna small subunit methyltransferase
BBR_RS19305	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BBR_RS19305	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BBR_RS19310	COG2270	Major facilitator Superfamily
BBR_RS19375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BBR_RS19380	COG4770	biotin carboxylase activity
BBR_RS19385	COG1268	BioY protein
BBR_RS19420	COG0250	Participates in transcription elongation, termination and antitermination
BBR_RS19425	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BBR_RS19435	COG0436	Aminotransferase
BBR_RS19465	COG1530	ribonuclease E activity
BBR_RS19470	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BBR_RS19480	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BBR_RS19500	COG4948	Mandelate Racemase Muconate Lactonizing
BBR_RS19505	COG1609	Transcriptional regulator
BBR_RS19535	COG0083	homoserine kinase activity
BBR_RS19540	COG0460	homoserine dehydrogenase
BBR_RS19545	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBR_RS19545	COG1263	PTS System
BBR_RS19545	COG2190	(PTS) system
BBR_RS19550	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBR_RS19550	COG1263	PTS System
BBR_RS19550	COG2190	(PTS) system
BBR_RS19565	COG1309	transcriptional regulator
BBR_RS19575	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BBR_RS19580	COG0446	pyridine nucleotide-disulphide oxidoreductase
BBR_RS19590	COG0765	amino acid transport
BBR_RS19605	COG1126	abc transporter atp-binding protein
BBR_RS19610	COG0167	dihydroorotate dehydrogenase activity
BBR_RS19645	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BBR_RS19650	COG0406	alpha-ribazole phosphatase activity
BBR_RS19650	COG0494	nUDIX hydrolase
BBR_RS19690	COG0584	glycerophosphoryl diester phosphodiesterase
BBR_RS19710	COG0179	Fumarylacetoacetate (FAA) hydrolase
BBR_RS19735	COG1216	Glycosyl transferase, family 2
BBR_RS19735	COG1442	glycosyl transferase family 8
BBR_RS19745	COG1368	sulfuric ester hydrolase activity
BBR_RS19750	COG1368	sulfuric ester hydrolase activity
BBR_RS19775	COG1216	Glycosyl transferase, family 2
BBR_RS19790	COG1088	dTDP-glucose 4,6-dehydratase activity
BBR_RS19810	COG1316	TRANSCRIPTIONal
BBR_RS19815	COG0577	efflux transmembrane transporter activity
BBR_RS19820	COG1129	ABC transporter
BBR_RS19840	COG0084	hydrolase, TatD family'
BBR_RS19845	COG1132	(ABC) transporter
BBR_RS19850	COG1132	(ABC) transporter
BBR_RS19875	COG4166	transmembrane transport
BBR_RS19945	COG1846	Transcriptional regulator
BBR_RS19980	COG1609	Transcriptional regulator
BBR_RS19995	COG1172	Belongs to the binding-protein-dependent transport system permease family
BBR_RS20000	COG1129	ABC transporter
BBR_RS20035	COG3293	Transposase
BBR_RS20040	COG1113	amino acid transport
BBR_RS20050	COG0577	efflux transmembrane transporter activity
BBR_RS20050	COG1136	(ABC) transporter
BBR_RS20055	COG1113	amino acid transport
BBR_RS20075	COG1609	Transcriptional regulator
BBR_RS20080	COG2182	Extracellular solute-binding protein
BBR_RS20085	COG0588	phosphoglycerate mutase activity
BBR_RS20125	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BBR_RS20130	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BBR_RS20135	COG0366	Alpha amylase catalytic
BBR_RS20145	COG0366	Alpha amylase catalytic
BBR_RS20150	COG0395	ABC-type sugar transport system, permease component
BBR_RS20170	COG1609	Transcriptional regulator
BBR_RS20175	COG1609	Transcriptional regulator
BBR_RS20180	COG0395	ABC-type sugar transport system, permease component
BBR_RS20185	COG1175	transmembrane transport
BBR_RS20205	COG0037	tRNA processing
BBR_RS20205	COG0590	tRNA wobble adenosine to inosine editing
BBR_RS20215	COG0025	NhaP-type Na H and K H
BBR_RS20220	COG0730	response to heat
BBR_RS20245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BBR_RS20255	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBR_RS20255	COG2190	(PTS) system
BBR_RS20255	COG1263	PTS System
BBR_RS20260	COG1263	PTS System
BBR_RS20260	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BBR_RS20270	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BBR_RS20310	COG3842	ATPase activity
BBR_RS20315	COG2188	Transcriptional regulator
BBR_RS20330	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BBR_RS20335	COG1215	transferase activity, transferring glycosyl groups
BBR_RS20355	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BBR_RS20375	COG1472	Belongs to the glycosyl hydrolase 3 family
BBR_RS20390	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BBR_RS20395	COG1472	Belongs to the glycosyl hydrolase 3 family
BBR_RS20415	COG3583	domain protein
BBR_RS20435	COG0617	tRNA 3'-terminal CCA addition
BBR_RS20455	COG0492	ferredoxin-NADP+ reductase activity
BBR_RS20460	COG1475	DNA binding
BBR_RS20465	COG1192	Involved in chromosome partitioning
BBR_RS20475	COG1847	R3H domain protein