locus-tag	class	description
J7M35_RS00010	COG0592	DNA-directed DNA polymerase activity
J7M35_RS00025	COG0187	DNA topoisomerase II activity
J7M35_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J7M35_RS00040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
J7M35_RS00045	COG1609	Transcriptional regulator
J7M35_RS00060	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J7M35_RS00065	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
J7M35_RS00075	COG1970	mechanosensitive ion channel activity
J7M35_RS00180	COG0783	Belongs to the Dps family
J7M35_RS00185	COG1253	flavin adenine dinucleotide binding
J7M35_RS00200	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
J7M35_RS00210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
J7M35_RS00215	COG0180	Tryptophanyl-tRNA synthetase
J7M35_RS00230	COG0058	SHG alpha-glucan phosphorylase activity
J7M35_RS00260	COG3764	Sortase (surface protein transpeptidase)
J7M35_RS00275	COG0515	serine threonine protein kinase
J7M35_RS00280	COG0768	penicillin binding
J7M35_RS00325	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
J7M35_RS00330	COG0697	spore germination
J7M35_RS00335	COG2910	NAD(P)H-binding
J7M35_RS00340	COG1733	regulation of RNA biosynthetic process
J7M35_RS00350	COG0343	queuine tRNA-ribosyltransferase activity
J7M35_RS00360	COG2217	Heavy metal translocating P-type atpase
J7M35_RS00365	COG0252	asparaginase activity
J7M35_RS00370	COG1113	amino acid transport
J7M35_RS00380	COG0493	'glutamate synthase
J7M35_RS00445	COG4974	Belongs to the 'phage' integrase family
J7M35_RS00500	COG0732	type I restriction modification DNA specificity domain
J7M35_RS00505	COG0732	type I restriction modification DNA specificity domain
J7M35_RS00515	COG3843	relaxase mobilization nuclease domain protein
J7M35_RS00545	COG0191	fructose-bisphosphate aldolase activity
J7M35_RS00620	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
J7M35_RS00625	COG1984	allophanate hydrolase subunit 2
J7M35_RS00630	COG4770	biotin carboxylase activity
J7M35_RS00680	COG0477	Major facilitator Superfamily
J7M35_RS00715	COG1175	transmembrane transport
J7M35_RS00730	COG1609	Transcriptional regulator
J7M35_RS00735	COG1609	Transcriptional regulator
J7M35_RS00745	COG1175	transmembrane transport
J7M35_RS00750	COG0395	ABC-type sugar transport system, permease component
J7M35_RS00775	COG1609	Transcriptional regulator
J7M35_RS00785	COG1113	amino acid transport
J7M35_RS00795	COG1653	transport
J7M35_RS00805	COG0395	ABC-type sugar transport system, permease component
J7M35_RS00840	COG1113	amino acid transport
J7M35_RS00865	COG1846	Transcriptional regulator
J7M35_RS00910	COG3250	beta-galactosidase activity
J7M35_RS00920	COG0672	)-iron permease
J7M35_RS00925	COG3470	protein probably involved in high-affinity Fe2 transport
J7M35_RS00940	COG0577	efflux transmembrane transporter activity
J7M35_RS00955	COG1609	Transcriptional regulator
J7M35_RS00960	COG1609	Transcriptional regulator
J7M35_RS00965	COG1129	ABC transporter
J7M35_RS00970	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7M35_RS00975	COG1879	ABC-type sugar transport system periplasmic component
J7M35_RS00980	COG1869	D-ribose catabolic process
J7M35_RS01015	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
J7M35_RS01030	COG1215	transferase activity, transferring glycosyl groups
J7M35_RS01035	COG1309	transcriptional regulator
J7M35_RS01060	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
J7M35_RS01065	COG0305	Participates in initiation and elongation during chromosome replication
J7M35_RS01070	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J7M35_RS01105	COG0584	glycerophosphoryl diester phosphodiesterase
J7M35_RS01120	COG0494	nUDIX hydrolase
J7M35_RS01120	COG0406	alpha-ribazole phosphatase activity
J7M35_RS01125	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
J7M35_RS01130	COG1309	transcriptional regulator
J7M35_RS01135	COG1472	Belongs to the glycosyl hydrolase 3 family
J7M35_RS01140	COG2211	Major facilitator Superfamily
J7M35_RS01185	COG3279	Response regulator of the LytR AlgR family
J7M35_RS01205	COG3250	beta-galactosidase activity
J7M35_RS01220	COG1309	transcriptional regulator
J7M35_RS01225	COG2169	Transcriptional regulator
J7M35_RS01275	COG3507	Belongs to the glycosyl hydrolase 43 family
J7M35_RS01285	COG1609	Transcriptional regulator
J7M35_RS01290	COG3940	Belongs to the glycosyl hydrolase 43 family
J7M35_RS01300	COG4209	transmembrane transport
J7M35_RS01305	COG0395	ABC-type sugar transport system, permease component
J7M35_RS01315	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J7M35_RS01320	COG1260	myo-inositol-1-phosphate synthase
J7M35_RS01340	COG1754	DNA topoisomerase type I activity
J7M35_RS01340	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J7M35_RS01350	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
J7M35_RS01355	COG1609	Transcriptional regulator
J7M35_RS01365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
J7M35_RS01410	COG3152	Membrane
J7M35_RS01465	COG2972	Histidine kinase
J7M35_RS01465	COG0745	RESPONSE REGULATOR receiver
J7M35_RS01470	COG0167	dihydroorotate dehydrogenase activity
J7M35_RS01475	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
J7M35_RS01535	COG3842	ATPase activity
J7M35_RS01570	COG0436	Aminotransferase
J7M35_RS01575	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
J7M35_RS01585	COG3265	gluconokinase activity
J7M35_RS01605	COG2270	Major facilitator Superfamily
J7M35_RS01625	COG0742	ribosomal rna small subunit methyltransferase
J7M35_RS01635	COG1027	Aspartate ammonia-lyase
J7M35_RS01645	COG1837	Belongs to the UPF0109 family
J7M35_RS01670	COG0519	Catalyzes the synthesis of GMP from XMP
J7M35_RS01675	COG0488	(ABC) transporter
J7M35_RS01720	COG0667	Aldo Keto reductase
J7M35_RS01725	COG0789	Transcriptional regulator
J7M35_RS01835	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
J7M35_RS01840	COG1136	(ABC) transporter
J7M35_RS01855	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
J7M35_RS01860	COG1530	ribonuclease E activity
J7M35_RS01885	COG0436	Aminotransferase
J7M35_RS01900	COG0250	Participates in transcription elongation, termination and antitermination
J7M35_RS01930	COG1268	BioY protein
J7M35_RS01935	COG4770	biotin carboxylase activity
J7M35_RS01940	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
J7M35_RS01980	COG1704	LemA family
J7M35_RS02000	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
J7M35_RS02005	COG0531	amino acid
J7M35_RS02015	COG0826	peptidase U32
J7M35_RS02030	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
J7M35_RS02040	COG3579	cysteine-type endopeptidase activity
J7M35_RS02045	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J7M35_RS02050	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
J7M35_RS02055	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
J7M35_RS02060	COG5002	protein histidine kinase activity
J7M35_RS02065	COG0745	RESPONSE REGULATOR receiver
J7M35_RS02100	COG0545	Peptidyl-prolyl cis-trans isomerase
J7M35_RS02130	COG0251	oxidation-reduction process
J7M35_RS02135	COG0833	amino acid
J7M35_RS02145	COG0019	diaminopimelate decarboxylase activity
J7M35_RS02155	COG0460	homoserine dehydrogenase
J7M35_RS02160	COG0083	homoserine kinase activity
J7M35_RS02170	COG1609	Transcriptional regulator
J7M35_RS02195	COG4988	ABC transporter
J7M35_RS02215	COG1175	transmembrane transport
J7M35_RS02220	COG0395	ABC-type sugar transport system, permease component
J7M35_RS02230	COG1609	Transcriptional regulator
J7M35_RS02240	COG0656	L-ascorbic acid biosynthetic process
J7M35_RS02255	COG2814	Major facilitator Superfamily
J7M35_RS02265	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
J7M35_RS02290	COG0577	efflux transmembrane transporter activity
J7M35_RS02295	COG0577	efflux transmembrane transporter activity
J7M35_RS02300	COG1136	(ABC) transporter
J7M35_RS02325	COG0227	Belongs to the bacterial ribosomal protein bL28 family
J7M35_RS02330	COG0267	Belongs to the bacterial ribosomal protein bL33 family
J7M35_RS02335	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
J7M35_RS02340	COG0257	Belongs to the bacterial ribosomal protein bL36 family
J7M35_RS02350	COG0803	Belongs to the bacterial solute-binding protein 9 family
J7M35_RS02350	COG3443	Belongs to the bacterial solute-binding protein 9 family
J7M35_RS02380	COG0402	S-adenosylhomocysteine deaminase activity
J7M35_RS02385	COG2233	PERMEase
J7M35_RS02415	COG0463	Glycosyl transferase, family 2
J7M35_RS02420	COG1088	dTDP-glucose 4,6-dehydratase activity
J7M35_RS02460	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J7M35_RS02465	COG0489	protein tyrosine kinase activity
J7M35_RS02475	COG0438	transferase activity, transferring glycosyl groups
J7M35_RS02490	COG1442	glycosyl transferase family 8
J7M35_RS02490	COG1216	Glycosyl transferase, family 2
J7M35_RS02495	COG1216	Glycosyl transferase, family 2
J7M35_RS02505	COG0438	transferase activity, transferring glycosyl groups
J7M35_RS02510	COG1216	Glycosyl transferase, family 2
J7M35_RS02510	COG1442	glycosyl transferase family 8
J7M35_RS02535	COG0438	transferase activity, transferring glycosyl groups
J7M35_RS02550	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
J7M35_RS02570	COG1376	ErfK ybiS ycfS ynhG family protein
J7M35_RS02600	COG0095	Lipoate-protein ligase
J7M35_RS02610	COG4499	WXG100 protein secretion system (Wss), protein YukC
J7M35_RS02610	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
J7M35_RS02615	COG1902	pentaerythritol trinitrate reductase activity
J7M35_RS02620	COG0167	dihydroorotate dehydrogenase activity
J7M35_RS02625	COG1216	Glycosyl transferase, family 2
J7M35_RS02630	COG1349	DNA-binding transcription factor activity
J7M35_RS02640	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
J7M35_RS02655	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J7M35_RS02665	COG0477	Major facilitator Superfamily
J7M35_RS02680	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
J7M35_RS02685	COG1194	a g-specific adenine glycosylase
J7M35_RS02735	COG0714	Associated with various cellular activities
J7M35_RS02745	COG2815	serine threonine protein kinase
J7M35_RS02745	COG0515	serine threonine protein kinase
J7M35_RS02770	COG0210	DNA helicase
J7M35_RS02795	COG1937	Protein conserved in bacteria
J7M35_RS02810	COG2807	transmembrane transport
J7M35_RS02820	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
J7M35_RS02840	COG0531	amino acid
J7M35_RS02845	COG0076	glutamate decarboxylase activity
J7M35_RS02880	COG1472	Belongs to the glycosyl hydrolase 3 family
J7M35_RS02910	COG0436	Aminotransferase
J7M35_RS02915	COG0110	maltose O-acetyltransferase activity
J7M35_RS02920	COG2186	Transcriptional regulator
J7M35_RS02930	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J7M35_RS02935	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J7M35_RS02940	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J7M35_RS02940	COG1116	anion transmembrane transporter activity
J7M35_RS02945	COG0154	amidase activity
J7M35_RS02970	COG3842	ATPase activity
J7M35_RS02985	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
J7M35_RS03000	COG0025	NhaP-type Na H and K H
J7M35_RS03005	COG0590	tRNA wobble adenosine to inosine editing
J7M35_RS03005	COG0037	tRNA processing
J7M35_RS03025	COG1175	transmembrane transport
J7M35_RS03030	COG0395	ABC-type sugar transport system, permease component
J7M35_RS03040	COG0366	Alpha amylase catalytic
J7M35_RS03045	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
J7M35_RS03050	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
J7M35_RS03090	COG0494	nUDIX hydrolase
J7M35_RS03105	COG0436	Aminotransferase
J7M35_RS03110	COG0248	Ppx GppA phosphatase
J7M35_RS03135	COG0765	amino acid transport
J7M35_RS03145	COG0765	amino acid transport
J7M35_RS03150	COG1126	abc transporter atp-binding protein
J7M35_RS03160	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J7M35_RS03190	COG1722	exodeoxyribonuclease VII activity
J7M35_RS03195	COG1570	exodeoxyribonuclease VII activity
J7M35_RS03200	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
J7M35_RS03200	COG1328	CTP reductase activity
J7M35_RS03220	COG2610	gluconate transmembrane transporter activity
J7M35_RS03225	COG1028	Short-chain dehydrogenase reductase Sdr
J7M35_RS03230	COG1609	Transcriptional regulator
J7M35_RS03245	COG1309	transcriptional regulator
J7M35_RS03280	COG3507	Belongs to the glycosyl hydrolase 43 family
J7M35_RS03290	COG3279	Response regulator of the LytR AlgR family
J7M35_RS03300	COG1309	transcriptional regulator
J7M35_RS03315	COG1309	transcriptional regulator
J7M35_RS03325	COG2211	Major facilitator Superfamily
J7M35_RS03335	COG0477	Major facilitator Superfamily
J7M35_RS03350	COG1028	Short-chain dehydrogenase reductase Sdr
J7M35_RS03355	COG2223	nitrite transmembrane transporter activity
J7M35_RS03360	COG0673	inositol 2-dehydrogenase activity
J7M35_RS03385	COG1132	(ABC) transporter
J7M35_RS03390	COG1132	(ABC) transporter
J7M35_RS03395	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
J7M35_RS03400	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J7M35_RS03405	COG1349	DNA-binding transcription factor activity
J7M35_RS03425	COG0477	Major facilitator Superfamily
J7M35_RS03435	COG2814	Major facilitator Superfamily
J7M35_RS03440	COG1609	Transcriptional regulator
J7M35_RS03445	COG3250	beta-galactosidase activity
J7M35_RS03485	COG1518	maintenance of DNA repeat elements
J7M35_RS03485	COG1468	defense response to virus
J7M35_RS03500	COG2094	Belongs to the DNA glycosylase MPG family
J7M35_RS03515	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
J7M35_RS03525	COG0613	PHP domain protein
J7M35_RS03550	COG3480	Lon protease (S16) C-terminal proteolytic domain
J7M35_RS03565	COG1733	regulation of RNA biosynthetic process
J7M35_RS03620	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J7M35_RS03630	COG2197	response regulator
J7M35_RS03660	COG0351	phosphomethylpyrimidine kinase
J7M35_RS03695	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
J7M35_RS03730	COG0587	DNA-directed DNA polymerase activity
J7M35_RS03770	COG1404	Belongs to the peptidase S8 family
J7M35_RS03795	COG1404	Belongs to the peptidase S8 family
J7M35_RS03830	COG1674	ftsk spoiiie
J7M35_RS03835	COG0174	glutamine synthetase
J7M35_RS03845	COG2814	Major facilitator Superfamily
J7M35_RS03850	COG1643	Atp-dependent helicase
J7M35_RS03855	COG2813	Specifically methylates the guanine in position
J7M35_RS03860	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
J7M35_RS03890	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
J7M35_RS03915	COG0768	penicillin binding
J7M35_RS03925	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
J7M35_RS03940	COG0772	Belongs to the SEDS family
J7M35_RS03985	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
J7M35_RS03985	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
J7M35_RS03990	COG1940	carbohydrate kinase activity
J7M35_RS04000	COG0601	transmembrane transport
J7M35_RS04020	COG0006	proline dipeptidase activity
J7M35_RS04025	COG0285	dihydrofolate synthase activity
J7M35_RS04030	COG1794	racemase activity, acting on amino acids and derivatives
J7M35_RS04050	COG1595	DNA-templated transcription, initiation
J7M35_RS04070	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
J7M35_RS04085	COG0367	asparagine synthase
J7M35_RS04090	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
J7M35_RS04120	COG0477	Major facilitator Superfamily
J7M35_RS04135	COG1217	gtp-binding protein TYPA
J7M35_RS04150	COG0287	Prephenate dehydrogenase
J7M35_RS04160	COG0577	efflux transmembrane transporter activity
J7M35_RS04160	COG1136	(ABC) transporter
J7M35_RS04165	COG0577	efflux transmembrane transporter activity
J7M35_RS04165	COG1136	(ABC) transporter
J7M35_RS04175	COG0747	negative chemotaxis
J7M35_RS04180	COG4166	transmembrane transport
J7M35_RS04185	COG0601	transmembrane transport
J7M35_RS04190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J7M35_RS04200	COG0708	Exodeoxyribonuclease III
J7M35_RS04230	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
J7M35_RS04235	COG0534	Mate efflux family protein
J7M35_RS04240	COG0110	maltose O-acetyltransferase activity
J7M35_RS04260	COG1131	(ABC) transporter
J7M35_RS04265	COG4585	Histidine kinase
J7M35_RS04270	COG2197	response regulator
J7M35_RS04280	COG0670	Belongs to the BI1 family
J7M35_RS04290	COG2357	RelA SpoT domain protein
J7M35_RS04320	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J7M35_RS04325	COG1546	Belongs to the CinA family
J7M35_RS04325	COG1058	Belongs to the CinA family
J7M35_RS04330	COG1396	sequence-specific DNA binding
J7M35_RS04345	COG2137	regulation of response to DNA damage stimulus
J7M35_RS04355	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
J7M35_RS04365	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
J7M35_RS04385	COG0142	geranyltranstransferase activity
J7M35_RS04395	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
J7M35_RS04400	COG0187	DNA topoisomerase II activity
J7M35_RS04420	COG3655	Transcriptional regulator
J7M35_RS04425	COG1201	RNA secondary structure unwinding
J7M35_RS04430	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
J7M35_RS04455	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
J7M35_RS04460	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
J7M35_RS04495	COG0489	protein tyrosine kinase activity
J7M35_RS04535	COG0739	heme binding
J7M35_RS04535	COG1196	nuclear chromosome segregation
J7M35_RS04535	COG0741	lytic transglycosylase activity
J7M35_RS04610	COG3843	relaxase mobilization nuclease domain protein
J7M35_RS04640	COG0551	DNA topoisomerase type I activity
J7M35_RS04640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
J7M35_RS04670	COG2217	Heavy metal translocating P-type atpase
J7M35_RS04685	COG4974	Belongs to the 'phage' integrase family
J7M35_RS04745	COG0561	phosphatase activity
J7M35_RS04750	COG1464	Belongs to the NlpA lipoprotein family
J7M35_RS04760	COG2011	ABC-type metal ion transport system permease component
J7M35_RS04765	COG1473	amidohydrolase
J7M35_RS04780	COG3835	regulator
J7M35_RS04785	COG2610	gluconate transmembrane transporter activity
J7M35_RS04790	COG1929	Belongs to the glycerate kinase type-1 family
J7M35_RS04795	COG1882	Formate acetyltransferase
J7M35_RS04820	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
J7M35_RS04820	COG1199	ATP-dependent helicase activity
J7M35_RS04830	COG1250	3-hydroxyacyl-CoA dehydrogenase
J7M35_RS04890	COG2169	Transcriptional regulator
J7M35_RS04900	COG0110	maltose O-acetyltransferase activity
J7M35_RS04905	COG1116	anion transmembrane transporter activity
J7M35_RS04910	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
J7M35_RS04915	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
J7M35_RS04925	COG0154	amidase activity
J7M35_RS04930	COG0154	amidase activity
J7M35_RS04935	COG1414	Transcriptional regulator
J7M35_RS04945	COG2267	carboxylic ester hydrolase activity
J7M35_RS04950	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
J7M35_RS04955	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
J7M35_RS04970	COG1063	alcohol dehydrogenase
J7M35_RS04980	COG1028	Short-chain dehydrogenase reductase Sdr
J7M35_RS05000	COG3189	MarR family transcriptional regulator
J7M35_RS05015	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
J7M35_RS05040	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
J7M35_RS05050	COG1228	amidohydrolase
J7M35_RS05075	COG1122	ATPase activity
J7M35_RS05110	COG1122	ATPase activity
J7M35_RS05120	COG1611	Belongs to the LOG family
J7M35_RS05185	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
J7M35_RS05200	COG1136	(ABC) transporter
J7M35_RS05205	COG0577	efflux transmembrane transporter activity
J7M35_RS05210	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
J7M35_RS05305	COG0569	domain protein
J7M35_RS05310	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
J7M35_RS05320	COG0497	DNA recombination
J7M35_RS05325	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
J7M35_RS05350	COG0395	ABC-type sugar transport system, permease component
J7M35_RS05355	COG1175	transmembrane transport
J7M35_RS05365	COG1609	Transcriptional regulator
J7M35_RS05395	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
J7M35_RS05415	COG0799	negative regulation of ribosome biogenesis
J7M35_RS05420	COG0406	alpha-ribazole phosphatase activity
J7M35_RS05440	COG3279	Response regulator of the LytR AlgR family
J7M35_RS05445	COG3275	phosphorelay sensor kinase activity
J7M35_RS05460	COG0598	Magnesium transport protein CorA
J7M35_RS05475	COG1555	photosystem II stabilization
J7M35_RS05475	COG1596	polysaccharide export
J7M35_RS05490	COG0802	atpase or kinase
J7M35_RS05500	COG0456	acetyltransferase
J7M35_RS05525	COG1022	Amp-dependent synthetase and ligase
J7M35_RS05540	COG0516	GMP reductase activity
J7M35_RS05610	COG0133	tryptophan synthase activity
J7M35_RS05625	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
J7M35_RS05640	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J7M35_RS05665	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
J7M35_RS05670	COG1560	Kdo2-lipid A biosynthetic process
J7M35_RS05675	COG0438	transferase activity, transferring glycosyl groups
J7M35_RS05710	COG0045	succinate-CoA ligase (ADP-forming) activity
J7M35_RS05735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J7M35_RS05775	COG4581	dead DEAH box helicase
J7M35_RS05800	COG1716	ATPase activity
J7M35_RS05860	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
J7M35_RS05865	COG0436	Aminotransferase
J7M35_RS05875	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
J7M35_RS05970	COG0281	malic enzyme
J7M35_RS05975	COG0488	(ABC) transporter
J7M35_RS05985	COG1335	isochorismatase
J7M35_RS05990	COG1122	ATPase activity
J7M35_RS05995	COG0488	(ABC) transporter
J7M35_RS06010	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
J7M35_RS06020	COG1063	alcohol dehydrogenase
J7M35_RS06050	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
J7M35_RS06050	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
J7M35_RS06070	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
J7M35_RS06080	COG0583	DNA-binding transcription factor activity
J7M35_RS06090	COG0167	dihydroorotate dehydrogenase activity
J7M35_RS06095	COG0543	2 iron, 2 sulfur cluster binding
J7M35_RS06100	COG0284	orotidine-5'-phosphate decarboxylase activity
J7M35_RS06105	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
J7M35_RS06135	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
J7M35_RS06155	COG1119	ATPase activity
J7M35_RS06160	COG0297	glycogen (starch) synthase activity
J7M35_RS06175	COG0069	glutamate synthase activity
J7M35_RS06175	COG0067	glutamate synthase
J7M35_RS06175	COG0070	glutamate synthase
J7M35_RS06195	COG2860	membrane
J7M35_RS06200	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
J7M35_RS06225	COG1454	alcohol dehydrogenase
J7M35_RS06235	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
J7M35_RS06240	COG2508	Transcriptional regulator
J7M35_RS06265	COG0577	efflux transmembrane transporter activity
J7M35_RS06265	COG1136	(ABC) transporter
J7M35_RS06275	COG0667	Aldo Keto reductase
J7M35_RS06280	COG0534	Mate efflux family protein
J7M35_RS06295	COG1309	transcriptional regulator
J7M35_RS06315	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
J7M35_RS06345	COG0537	adenosine 5'-monophosphoramidase activity
J7M35_RS06370	COG2151	metal-sulfur cluster biosynthetic enzyme
J7M35_RS06385	COG0396	ATPase activity
J7M35_RS06390	COG0719	Fe-S assembly protein
J7M35_RS06405	COG1523	belongs to the glycosyl hydrolase 13 family
J7M35_RS06410	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
J7M35_RS06470	COG0577	efflux transmembrane transporter activity
J7M35_RS06470	COG1136	(ABC) transporter
J7M35_RS06500	COG2755	lipolytic protein G-D-S-L family
J7M35_RS06500	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
J7M35_RS06505	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
J7M35_RS06510	COG0280	phosphate acetyltransferase
J7M35_RS06510	COG0857	belongs to the CobB CobQ family
J7M35_RS06535	COG2197	response regulator
J7M35_RS06550	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J7M35_RS06585	COG0494	nUDIX hydrolase
J7M35_RS06590	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
J7M35_RS06610	COG2323	membrane
J7M35_RS06630	COG0494	nUDIX hydrolase
J7M35_RS06635	COG0469	pyruvate kinase activity
J7M35_RS06655	COG0539	negative regulation of cytoplasmic translation
J7M35_RS06670	COG1121	(ABC) transporter
J7M35_RS06685	COG1329	Transcriptional regulator
J7M35_RS06695	COG0745	RESPONSE REGULATOR receiver
J7M35_RS06700	COG2205	protein histidine kinase activity
J7M35_RS06705	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
J7M35_RS06735	COG1316	TRANSCRIPTIONal
J7M35_RS06740	COG1316	TRANSCRIPTIONal
J7M35_RS06765	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
J7M35_RS06775	COG1760	l-serine dehydratase
J7M35_RS06835	COG1966	Carbon starvation protein
J7M35_RS06840	COG1687	branched-chain amino acid
J7M35_RS06845	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
J7M35_RS06850	COG2249	NAD(P)H dehydrogenase (quinone) activity
J7M35_RS06860	COG0583	DNA-binding transcription factor activity
J7M35_RS06865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
J7M35_RS06875	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
J7M35_RS06880	COG1028	Short-chain dehydrogenase reductase Sdr
J7M35_RS06900	COG0363	glucosamine-6-phosphate deaminase activity
J7M35_RS06905	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
J7M35_RS06910	COG3340	Belongs to the peptidase S51 family
J7M35_RS06915	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
J7M35_RS06920	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
J7M35_RS06925	COG1132	(ABC) transporter
J7M35_RS06930	COG0390	transport system, permease component
J7M35_RS06940	COG4221	oxidoreductase activity
J7M35_RS06945	COG2233	PERMEase
J7M35_RS06955	COG1917	Cupin 2, conserved barrel domain protein
J7M35_RS06955	COG2207	Transcriptional regulator
J7M35_RS06980	COG0583	DNA-binding transcription factor activity
J7M35_RS07010	COG2188	Transcriptional regulator
J7M35_RS07285	COG0012	GTP binding
J7M35_RS07290	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
J7M35_RS07300	COG4585	Histidine kinase
J7M35_RS07305	COG2197	response regulator
J7M35_RS07310	COG0577	efflux transmembrane transporter activity
J7M35_RS07310	COG1136	(ABC) transporter
J7M35_RS07315	COG1136	(ABC) transporter
J7M35_RS07325	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
J7M35_RS07330	COG1122	ATPase activity
J7M35_RS07340	COG2873	o-acetylhomoserine
J7M35_RS07360	COG0758	DNA mediated transformation
J7M35_RS07360	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
J7M35_RS07365	COG1053	succinate dehydrogenase
J7M35_RS07370	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
J7M35_RS07410	COG4166	transmembrane transport
J7M35_RS07415	COG2814	Major facilitator Superfamily
J7M35_RS07430	COG2326	polyphosphate kinase activity
J7M35_RS07435	COG0765	amino acid transport
J7M35_RS07440	COG0765	amino acid transport
J7M35_RS07445	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J7M35_RS07450	COG1126	abc transporter atp-binding protein
J7M35_RS07460	COG0765	amino acid transport
J7M35_RS07475	COG1196	nuclear chromosome segregation
J7M35_RS07490	COG0589	response to stress
J7M35_RS07505	COG2205	protein histidine kinase activity
J7M35_RS07510	COG0745	RESPONSE REGULATOR receiver
J7M35_RS07540	COG0714	Associated with various cellular activities
J7M35_RS07580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
J7M35_RS07605	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
J7M35_RS07620	COG4122	O-methyltransferase activity
J7M35_RS07625	COG1222	aaa ATPase
J7M35_RS07630	COG0560	Phosphoserine phosphatase
J7M35_RS07645	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
J7M35_RS07670	COG0284	orotidine-5'-phosphate decarboxylase activity
J7M35_RS07715	COG0385	Bile acid
J7M35_RS07745	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
J7M35_RS07790	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
J7M35_RS07795	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
J7M35_RS07805	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
J7M35_RS07810	COG0577	efflux transmembrane transporter activity
J7M35_RS07820	COG0577	efflux transmembrane transporter activity
J7M35_RS07820	COG1136	(ABC) transporter
J7M35_RS07835	COG0436	Aminotransferase
J7M35_RS07840	COG2011	ABC-type metal ion transport system permease component
J7M35_RS07845	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
J7M35_RS07855	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
J7M35_RS07865	COG4221	oxidoreductase activity
J7M35_RS07870	COG0789	Transcriptional regulator
J7M35_RS07875	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J7M35_RS07880	COG1126	abc transporter atp-binding protein
J7M35_RS07885	COG0765	amino acid transport
J7M35_RS07890	COG0765	amino acid transport
J7M35_RS07950	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
J7M35_RS07955	COG0531	amino acid
J7M35_RS07970	COG0514	ATP-dependent DNA helicase (RecQ)
J7M35_RS07990	COG4608	Belongs to the ABC transporter superfamily
J7M35_RS08000	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
J7M35_RS08005	COG0601	transmembrane transport
J7M35_RS08010	COG0747	negative chemotaxis
J7M35_RS08015	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
J7M35_RS08035	COG1609	Transcriptional regulator
J7M35_RS08050	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
J7M35_RS08065	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J7M35_RS08080	COG3942	CHAP domain
J7M35_RS08080	COG1388	LysM domain
J7M35_RS08085	COG2177	Part of the ABC transporter FtsEX involved in
J7M35_RS08090	COG2884	Cell division ATP-binding protein ftsE
J7M35_RS08095	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
J7M35_RS08115	COG0024	Methionine aminopeptidase
J7M35_RS08125	COG3590	peptidase
J7M35_RS08145	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
J7M35_RS08165	COG0366	Alpha amylase catalytic
J7M35_RS08170	COG1609	Transcriptional regulator
J7M35_RS08185	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
J7M35_RS08190	COG0009	L-threonylcarbamoyladenylate synthase
J7M35_RS08245	COG1070	Carbohydrate kinase
J7M35_RS08260	COG4214	carbohydrate transport
J7M35_RS08265	COG1129	ABC transporter
J7M35_RS08270	COG4213	ABC transporter substrate-binding protein
J7M35_RS08280	COG3507	Belongs to the glycosyl hydrolase 43 family
J7M35_RS08290	COG1175	transmembrane transport
J7M35_RS08295	COG1653	transport
J7M35_RS08300	COG1609	Transcriptional regulator
J7M35_RS08305	COG3507	Belongs to the glycosyl hydrolase 43 family
J7M35_RS08315	COG2873	o-acetylhomoserine
J7M35_RS08330	COG0242	peptide deformylase activity
J7M35_RS08360	COG1946	Acyl-CoA thioesterase
J7M35_RS08370	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
J7M35_RS08375	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
J7M35_RS08385	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
J7M35_RS08390	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
J7M35_RS08430	COG1454	alcohol dehydrogenase
J7M35_RS08475	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
J7M35_RS08515	COG0589	response to stress
J7M35_RS08520	COG0791	NLP P60 protein
J7M35_RS08525	COG3942	CHAP domain
J7M35_RS08525	COG1705	Flagellar rod assembly protein muramidase FlgJ
J7M35_RS08530	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
J7M35_RS08545	COG5002	protein histidine kinase activity
J7M35_RS08550	COG0704	Plays a role in the regulation of phosphate uptake
J7M35_RS08555	COG4716	Myosin-crossreactive antigen
J7M35_RS08575	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
J7M35_RS08605	COG2814	Major facilitator Superfamily
J7M35_RS08610	COG1132	(ABC) transporter
J7M35_RS08610	COG2375	cellular response to nickel ion
J7M35_RS08650	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J7M35_RS08660	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
J7M35_RS08680	COG1803	Methylglyoxal synthase
J7M35_RS08680	COG1597	lipid kinase activity
J7M35_RS08685	COG3711	transcriptional antiterminator
J7M35_RS08705	COG3290	protein histidine kinase activity
J7M35_RS08710	COG0328	RNA-DNA hybrid ribonuclease activity
J7M35_RS08735	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
J7M35_RS08740	COG0402	S-adenosylhomocysteine deaminase activity
J7M35_RS08750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J7M35_RS08755	COG0765	amino acid transport
J7M35_RS08760	COG1126	abc transporter atp-binding protein
J7M35_RS08765	COG0196	riboflavin kinase activity
J7M35_RS08805	COG2308	Evidence 4 Homologs of previously reported genes of
J7M35_RS08910	COG0255	Belongs to the universal ribosomal protein uL29 family
J7M35_RS08965	COG1454	alcohol dehydrogenase
J7M35_RS08965	COG1012	belongs to the aldehyde dehydrogenase family
J7M35_RS09010	COG1739	Uncharacterized protein family UPF0029
J7M35_RS09015	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
J7M35_RS09035	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
J7M35_RS09050	COG0531	amino acid
J7M35_RS09055	COG0812	UDP-N-acetylmuramate dehydrogenase activity
J7M35_RS09100	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
J7M35_RS09130	COG0534	Mate efflux family protein
J7M35_RS09145	COG2252	PERMEase
J7M35_RS09165	COG1131	(ABC) transporter
J7M35_RS09205	COG0355	proton-transporting ATP synthase activity, rotational mechanism
J7M35_RS09240	COG0356	it plays a direct role in the translocation of protons across the membrane
J7M35_RS09260	COG0679	Auxin Efflux Carrier
J7M35_RS09265	COG0028	Belongs to the TPP enzyme family
J7M35_RS09300	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
J7M35_RS09315	COG0745	RESPONSE REGULATOR receiver
J7M35_RS09320	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
J7M35_RS09325	COG0747	negative chemotaxis
J7M35_RS09340	COG0287	Prephenate dehydrogenase
J7M35_RS09340	COG1605	Chorismate mutase
J7M35_RS09345	COG1522	sequence-specific DNA binding
J7M35_RS09405	COG1322	Protein conserved in bacteria
J7M35_RS09420	COG0179	Fumarylacetoacetate (FAA) hydrolase
J7M35_RS09445	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
J7M35_RS09465	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
J7M35_RS09475	COG1122	ATPase activity
J7M35_RS09525	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
J7M35_RS09550	COG1368	sulfuric ester hydrolase activity
J7M35_RS09560	COG2244	polysaccharide biosynthetic process
J7M35_RS09570	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
J7M35_RS09585	COG3754	Rhamnan synthesis protein F
J7M35_RS09605	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
J7M35_RS09625	COG1216	Glycosyl transferase, family 2
J7M35_RS09665	COG1216	Glycosyl transferase, family 2
J7M35_RS09670	COG3867	Arabinogalactan endo-beta-1,4-galactanase
J7M35_RS09675	COG3594	Acyltransferase
J7M35_RS09690	COG0463	Glycosyl transferase, family 2
J7M35_RS09725	COG0701	Predicted permease
J7M35_RS09735	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
J7M35_RS09740	COG0765	amino acid transport
J7M35_RS09755	COG1126	abc transporter atp-binding protein
J7M35_RS09825	COG1136	(ABC) transporter
J7M35_RS09825	COG0577	efflux transmembrane transporter activity
J7M35_RS09845	COG0084	hydrolase, TatD family'
J7M35_RS09865	COG1609	Transcriptional regulator
J7M35_RS09875	COG1879	ABC-type sugar transport system periplasmic component
J7M35_RS09880	COG1172	Belongs to the binding-protein-dependent transport system permease family
J7M35_RS09885	COG1129	ABC transporter
J7M35_RS09930	COG0395	ABC-type sugar transport system, permease component
J7M35_RS09935	COG4209	transmembrane transport
J7M35_RS09950	COG3250	beta-galactosidase activity
J7M35_RS09955	COG1132	(ABC) transporter
J7M35_RS09960	COG1132	(ABC) transporter
J7M35_RS10010	COG3459	Glycosyltransferase 36 associated
J7M35_RS10025	COG1609	Transcriptional regulator
J7M35_RS10035	COG1012	belongs to the aldehyde dehydrogenase family
J7M35_RS10040	COG1177	transmembrane transport
J7M35_RS10045	COG1176	ABC-type spermidine putrescine transport system, permease component I
J7M35_RS10050	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
J7M35_RS10055	COG3842	ATPase activity
J7M35_RS10070	COG1454	alcohol dehydrogenase
J7M35_RS10075	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
J7M35_RS10095	COG3507	Belongs to the glycosyl hydrolase 43 family
J7M35_RS10100	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
J7M35_RS10110	COG1501	Belongs to the glycosyl hydrolase 31 family
J7M35_RS10115	COG1472	Belongs to the glycosyl hydrolase 3 family
J7M35_RS10135	COG0395	ABC-type sugar transport system, permease component
J7M35_RS10140	COG4209	transmembrane transport
J7M35_RS10150	COG1501	Belongs to the glycosyl hydrolase 31 family
J7M35_RS10160	COG1175	transmembrane transport
J7M35_RS10165	COG1653	transport
J7M35_RS10170	COG1609	Transcriptional regulator
J7M35_RS10180	COG0395	ABC-type sugar transport system, permease component
J7M35_RS10185	COG1175	transmembrane transport
J7M35_RS10195	COG1609	Transcriptional regulator
J7M35_RS10200	COG0586	Pfam SNARE associated Golgi protein
J7M35_RS10220	COG0789	Transcriptional regulator
J7M35_RS10240	COG1785	Belongs to the alkaline phosphatase family
J7M35_RS10245	COG1501	Belongs to the glycosyl hydrolase 31 family
J7M35_RS10250	COG0395	ABC-type sugar transport system, permease component
J7M35_RS10255	COG1175	transmembrane transport
J7M35_RS10265	COG1609	Transcriptional regulator
J7M35_RS10270	COG0730	response to heat
J7M35_RS10295	COG1609	Transcriptional regulator
J7M35_RS10310	COG1523	belongs to the glycosyl hydrolase 13 family
J7M35_RS10315	COG3833	ABC-type maltose transport systems, permease component
J7M35_RS10320	COG1175	transmembrane transport
J7M35_RS10340	COG0366	Alpha amylase catalytic
J7M35_RS10360	COG1609	Transcriptional regulator
J7M35_RS10370	COG0406	alpha-ribazole phosphatase activity
J7M35_RS10385	COG3250	beta-galactosidase activity
J7M35_RS10400	COG0745	RESPONSE REGULATOR receiver
J7M35_RS10455	COG3583	domain protein
J7M35_RS10475	COG0617	tRNA 3'-terminal CCA addition
J7M35_RS10495	COG0028	Belongs to the TPP enzyme family
J7M35_RS10500	COG0492	ferredoxin-NADP+ reductase activity
J7M35_RS10510	COG1192	Involved in chromosome partitioning
J7M35_RS10520	COG1847	R3H domain protein