locus-tag	class	description
BE0216_RS00025	COG1904	glucuronate isomerase
BE0216_RS00035	COG1609	Transcriptional regulator
BE0216_RS00040	COG1609	Transcriptional regulator
BE0216_RS00050	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BE0216_RS00055	COG1028	Short-chain dehydrogenase reductase Sdr
BE0216_RS00075	COG1175	transmembrane transport
BE0216_RS00080	COG0395	ABC-type sugar transport system, permease component
BE0216_RS00110	COG2721	sulfolactate sulfo-lyase activity
BE0216_RS00135	COG0142	geranyltranstransferase activity
BE0216_RS00145	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BE0216_RS00150	COG0187	DNA topoisomerase II activity
BE0216_RS00165	COG3655	Transcriptional regulator
BE0216_RS00185	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BE0216_RS00210	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BE0216_RS00215	COG0577	efflux transmembrane transporter activity
BE0216_RS00215	COG1136	(ABC) transporter
BE0216_RS00235	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS00245	COG0586	Pfam SNARE associated Golgi protein
BE0216_RS00250	COG5002	protein histidine kinase activity
BE0216_RS00255	COG0745	RESPONSE REGULATOR receiver
BE0216_RS00265	COG0390	transport system, permease component
BE0216_RS00270	COG0667	Aldo Keto reductase
BE0216_RS00345	COG0583	DNA-binding transcription factor activity
BE0216_RS00360	COG2801	Transposase and inactivated derivatives
BE0216_RS00365	COG0667	Aldo Keto reductase
BE0216_RS00405	COG2249	NAD(P)H dehydrogenase (quinone) activity
BE0216_RS00415	COG0667	Aldo Keto reductase
BE0216_RS00425	COG0656	L-ascorbic acid biosynthetic process
BE0216_RS00435	COG0583	DNA-binding transcription factor activity
BE0216_RS00445	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BE0216_RS00455	COG0667	Aldo Keto reductase
BE0216_RS00465	COG0667	Aldo Keto reductase
BE0216_RS00470	COG0583	DNA-binding transcription factor activity
BE0216_RS00485	COG0561	phosphatase activity
BE0216_RS00495	COG1473	amidohydrolase
BE0216_RS00505	COG1882	Formate acetyltransferase
BE0216_RS00530	COG3956	TIGRFAM MazG family protein
BE0216_RS00620	COG1228	amidohydrolase
BE0216_RS00655	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BE0216_RS00660	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BE0216_RS00665	COG1611	Belongs to the LOG family
BE0216_RS00705	COG2873	o-acetylhomoserine
BE0216_RS00710	COG0577	efflux transmembrane transporter activity
BE0216_RS00710	COG1136	(ABC) transporter
BE0216_RS00725	COG2197	response regulator
BE0216_RS00730	COG4585	Histidine kinase
BE0216_RS00740	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BE0216_RS00745	COG0012	GTP binding
BE0216_RS00750	COG0583	DNA-binding transcription factor activity
BE0216_RS00760	COG2207	Transcriptional regulator
BE0216_RS00770	COG0702	epimerase
BE0216_RS00775	COG3304	Inner membrane component domain
BE0216_RS00780	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BE0216_RS00785	COG2233	PERMEase
BE0216_RS00795	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BE0216_RS00800	COG1349	DNA-binding transcription factor activity
BE0216_RS00820	COG0477	Major facilitator Superfamily
BE0216_RS00825	COG4221	oxidoreductase activity
BE0216_RS00835	COG1129	ABC transporter
BE0216_RS00855	COG2361	Protein of unknown function DUF86
BE0216_RS00860	COG0583	DNA-binding transcription factor activity
BE0216_RS00875	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BE0216_RS00880	COG0789	Transcriptional regulator
BE0216_RS00930	COG0577	efflux transmembrane transporter activity
BE0216_RS00935	COG0577	efflux transmembrane transporter activity
BE0216_RS00935	COG1136	(ABC) transporter
BE0216_RS00950	COG1966	Carbon starvation protein
BE0216_RS00985	COG2197	response regulator
BE0216_RS00990	COG4585	Histidine kinase
BE0216_RS00995	COG1131	(ABC) transporter
BE0216_RS01040	COG1136	(ABC) transporter
BE0216_RS01040	COG0577	efflux transmembrane transporter activity
BE0216_RS01050	COG0588	phosphoglycerate mutase activity
BE0216_RS01095	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BE0216_RS01105	COG1376	ErfK ybiS ycfS ynhG family protein
BE0216_RS01115	COG0719	Fe-S assembly protein
BE0216_RS01120	COG0396	ATPase activity
BE0216_RS01130	COG0822	iron-sulfur transferase activity
BE0216_RS01135	COG2151	metal-sulfur cluster biosynthetic enzyme
BE0216_RS01175	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BE0216_RS01180	COG0537	adenosine 5'-monophosphoramidase activity
BE0216_RS01185	COG1702	phosphate starvation-inducible protein PhoH
BE0216_RS01210	COG5002	protein histidine kinase activity
BE0216_RS01210	COG3850	Histidine kinase
BE0216_RS01245	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS01250	COG0583	DNA-binding transcription factor activity
BE0216_RS01260	COG1028	Short-chain dehydrogenase reductase Sdr
BE0216_RS01270	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BE0216_RS01295	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BE0216_RS01300	COG2860	membrane
BE0216_RS01320	COG0069	glutamate synthase activity
BE0216_RS01320	COG0067	glutamate synthase
BE0216_RS01320	COG0070	glutamate synthase
BE0216_RS01345	COG0297	glycogen (starch) synthase activity
BE0216_RS01350	COG1119	ATPase activity
BE0216_RS01390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BE0216_RS01395	COG0284	orotidine-5'-phosphate decarboxylase activity
BE0216_RS01400	COG0543	2 iron, 2 sulfur cluster binding
BE0216_RS01405	COG0167	dihydroorotate dehydrogenase activity
BE0216_RS01420	COG0583	DNA-binding transcription factor activity
BE0216_RS01425	COG1609	Transcriptional regulator
BE0216_RS01430	COG3250	beta-galactosidase activity
BE0216_RS01435	COG2211	Major facilitator Superfamily
BE0216_RS01460	COG0577	efflux transmembrane transporter activity
BE0216_RS01485	COG0584	glycerophosphoryl diester phosphodiesterase
BE0216_RS01495	COG0488	(ABC) transporter
BE0216_RS01530	COG2873	o-acetylhomoserine
BE0216_RS01540	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BE0216_RS01570	COG4166	transmembrane transport
BE0216_RS01575	COG1733	regulation of RNA biosynthetic process
BE0216_RS01580	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BE0216_RS01590	COG0436	Aminotransferase
BE0216_RS01595	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BE0216_RS01635	COG4868	Belongs to the UPF0371 family
BE0216_RS01660	COG1136	(ABC) transporter
BE0216_RS01700	COG2197	response regulator
BE0216_RS01715	COG1136	(ABC) transporter
BE0216_RS01730	COG1653	transport
BE0216_RS01775	COG0045	succinate-CoA ligase (ADP-forming) activity
BE0216_RS01865	COG1716	ATPase activity
BE0216_RS01885	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BE0216_RS01900	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BE0216_RS01915	COG0133	tryptophan synthase activity
BE0216_RS01925	COG4181	ATPase activity
BE0216_RS01935	COG4585	Histidine kinase
BE0216_RS01940	COG2197	response regulator
BE0216_RS01970	COG1876	peptidase activity
BE0216_RS02020	COG1116	anion transmembrane transporter activity
BE0216_RS02055	COG3231	kanamycin kinase activity
BE0216_RS02065	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BE0216_RS02095	COG0516	GMP reductase activity
BE0216_RS02110	COG1022	Amp-dependent synthetase and ligase
BE0216_RS02135	COG0456	acetyltransferase
BE0216_RS02145	COG0802	atpase or kinase
BE0216_RS02160	COG2197	response regulator
BE0216_RS02165	COG4585	Histidine kinase
BE0216_RS02185	COG1131	(ABC) transporter
BE0216_RS02195	COG0598	Magnesium transport protein CorA
BE0216_RS02225	COG0492	ferredoxin-NADP+ reductase activity
BE0216_RS02260	COG0799	negative regulation of ribosome biogenesis
BE0216_RS02280	COG2755	lipolytic protein G-D-S-L family
BE0216_RS02280	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BE0216_RS02295	COG0300	oxidoreductase activity
BE0216_RS02305	COG0242	peptide deformylase activity
BE0216_RS02310	COG1136	(ABC) transporter
BE0216_RS02320	COG2205	protein histidine kinase activity
BE0216_RS02325	COG0745	RESPONSE REGULATOR receiver
BE0216_RS02340	COG1373	ATPase (AAA superfamily
BE0216_RS02355	COG0857	belongs to the CobB CobQ family
BE0216_RS02355	COG0280	phosphate acetyltransferase
BE0216_RS02360	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BE0216_RS02395	COG1051	belongs to the nudix hydrolase family
BE0216_RS02400	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BE0216_RS02415	COG0494	nUDIX hydrolase
BE0216_RS02450	COG1192	Involved in chromosome partitioning
BE0216_RS02495	COG1705	Flagellar rod assembly protein muramidase FlgJ
BE0216_RS02495	COG3942	CHAP domain
BE0216_RS02545	COG3843	relaxase mobilization nuclease domain protein
BE0216_RS02555	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BE0216_RS02555	COG0551	DNA topoisomerase type I activity
BE0216_RS02595	COG0582	viral genome integration into host DNA
BE0216_RS02600	COG0469	pyruvate kinase activity
BE0216_RS02620	COG2197	response regulator
BE0216_RS02630	COG0577	efflux transmembrane transporter activity
BE0216_RS02630	COG1136	(ABC) transporter
BE0216_RS02640	COG0539	negative regulation of cytoplasmic translation
BE0216_RS02655	COG1121	(ABC) transporter
BE0216_RS02670	COG1329	Transcriptional regulator
BE0216_RS02680	COG0745	RESPONSE REGULATOR receiver
BE0216_RS02685	COG2205	protein histidine kinase activity
BE0216_RS02725	COG1316	TRANSCRIPTIONal
BE0216_RS02750	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BE0216_RS02760	COG1760	l-serine dehydratase
BE0216_RS02795	COG1950	PFAM Membrane protein of
BE0216_RS02805	COG0477	Major facilitator Superfamily
BE0216_RS02815	COG3655	Transcriptional regulator
BE0216_RS02870	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BE0216_RS02880	COG0667	Aldo Keto reductase
BE0216_RS02885	COG0789	Transcriptional regulator
BE0216_RS02890	COG2116	formate transmembrane transporter activity
BE0216_RS02910	COG1247	-acetyltransferase
BE0216_RS02925	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BE0216_RS02955	COG0450	alkyl hydroperoxide reductase
BE0216_RS02970	COG1131	(ABC) transporter
BE0216_RS02980	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BE0216_RS03095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BE0216_RS03115	COG1136	(ABC) transporter
BE0216_RS03140	COG1122	ATPase activity
BE0216_RS03145	COG4721	ABC-type cobalt transport system, permease component
BE0216_RS03150	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BE0216_RS03175	COG0488	(ABC) transporter
BE0216_RS03175	COG0488	(ABC) transporter
BE0216_RS03185	COG0371	Dehydrogenase
BE0216_RS03220	COG1122	ATPase activity
BE0216_RS03225	COG0436	Aminotransferase
BE0216_RS03260	COG2814	Major facilitator Superfamily
BE0216_RS03275	COG2326	polyphosphate kinase activity
BE0216_RS03280	COG0366	Alpha amylase catalytic
BE0216_RS03290	COG0765	amino acid transport
BE0216_RS03295	COG0765	amino acid transport
BE0216_RS03300	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BE0216_RS03305	COG2801	Transposase and inactivated derivatives
BE0216_RS03315	COG1126	abc transporter atp-binding protein
BE0216_RS03335	COG1196	nuclear chromosome segregation
BE0216_RS03365	COG2205	protein histidine kinase activity
BE0216_RS03370	COG0745	RESPONSE REGULATOR receiver
BE0216_RS03395	COG2801	Transposase and inactivated derivatives
BE0216_RS03410	COG0714	Associated with various cellular activities
BE0216_RS03485	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BE0216_RS03520	COG1121	(ABC) transporter
BE0216_RS03525	COG2197	response regulator
BE0216_RS03540	COG0586	Pfam SNARE associated Golgi protein
BE0216_RS03545	COG0560	Phosphoserine phosphatase
BE0216_RS03560	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BE0216_RS03580	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BE0216_RS03590	COG0284	orotidine-5'-phosphate decarboxylase activity
BE0216_RS03930	COG1949	3'-to-5' exoribonuclease specific for small oligoribonucleotides
BE0216_RS04130	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BE0216_RS04135	COG2197	response regulator
BE0216_RS04150	COG4181	ATPase activity
BE0216_RS04155	COG0577	efflux transmembrane transporter activity
BE0216_RS04155	COG1136	(ABC) transporter
BE0216_RS04165	COG0363	glucosamine-6-phosphate deaminase activity
BE0216_RS04185	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BE0216_RS04195	COG1487	ribonuclease activity
BE0216_RS04200	COG1373	ATPase (AAA superfamily
BE0216_RS04210	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BE0216_RS04230	COG1012	belongs to the aldehyde dehydrogenase family
BE0216_RS04235	COG1028	Short-chain dehydrogenase reductase Sdr
BE0216_RS04260	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BE0216_RS04265	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BE0216_RS04275	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BE0216_RS04290	COG0577	efflux transmembrane transporter activity
BE0216_RS04290	COG1136	(ABC) transporter
BE0216_RS04295	COG1733	regulation of RNA biosynthetic process
BE0216_RS04300	COG2910	NAD(P)H-binding
BE0216_RS04320	COG0300	oxidoreductase activity
BE0216_RS04350	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BE0216_RS04360	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BE0216_RS04365	COG3842	ATPase activity
BE0216_RS04380	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BE0216_RS04385	COG0358	DNA primase activity
BE0216_RS04405	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BE0216_RS04405	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BE0216_RS04410	COG1397	ADP-ribosylglycohydrolase
BE0216_RS04475	COG0395	ABC-type sugar transport system, permease component
BE0216_RS04480	COG4209	transmembrane transport
BE0216_RS04485	COG1653	transport
BE0216_RS04495	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BE0216_RS04505	COG2610	gluconate transmembrane transporter activity
BE0216_RS04510	COG1028	Short-chain dehydrogenase reductase Sdr
BE0216_RS04515	COG1609	Transcriptional regulator
BE0216_RS04520	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
BE0216_RS04530	COG3265	gluconokinase activity
BE0216_RS04550	COG0514	ATP-dependent DNA helicase (RecQ)
BE0216_RS04555	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
BE0216_RS04560	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
BE0216_RS04565	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BE0216_RS04580	COG1609	Transcriptional regulator
BE0216_RS04590	COG1131	(ABC) transporter
BE0216_RS04595	COG1131	(ABC) transporter
BE0216_RS04620	COG1131	(ABC) transporter
BE0216_RS04630	COG4608	Belongs to the ABC transporter superfamily
BE0216_RS04640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BE0216_RS04650	COG4166	transmembrane transport
BE0216_RS04665	COG1653	transport
BE0216_RS04685	COG1609	Transcriptional regulator
BE0216_RS04695	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BE0216_RS04700	COG1126	abc transporter atp-binding protein
BE0216_RS04720	COG1388	LysM domain
BE0216_RS04720	COG3942	CHAP domain
BE0216_RS04725	COG2177	Part of the ABC transporter FtsEX involved in
BE0216_RS04730	COG2884	Cell division ATP-binding protein ftsE
BE0216_RS04735	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BE0216_RS04755	COG1454	alcohol dehydrogenase
BE0216_RS04770	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BE0216_RS04795	COG1695	Transcriptional regulator
BE0216_RS04825	COG0395	ABC-type sugar transport system, permease component
BE0216_RS04830	COG1175	transmembrane transport
BE0216_RS04835	COG2182	Extracellular solute-binding protein
BE0216_RS04860	COG0589	response to stress
BE0216_RS04875	COG1388	LysM domain
BE0216_RS04875	COG3942	CHAP domain
BE0216_RS04880	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BE0216_RS04890	COG5002	protein histidine kinase activity
BE0216_RS04895	COG0704	Plays a role in the regulation of phosphate uptake
BE0216_RS04915	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BE0216_RS04925	COG2814	Major facilitator Superfamily
BE0216_RS04955	COG2197	response regulator
BE0216_RS04980	COG0395	ABC-type sugar transport system, permease component
BE0216_RS04985	COG1175	transmembrane transport
BE0216_RS05025	COG1803	Methylglyoxal synthase
BE0216_RS05025	COG1597	lipid kinase activity
BE0216_RS05035	COG1904	glucuronate isomerase
BE0216_RS05040	COG0800	Aldolase
BE0216_RS05050	COG1312	Catalyzes the dehydration of D-mannonate
BE0216_RS05055	COG0246	Mannitol dehydrogenase
BE0216_RS05060	COG1609	Transcriptional regulator
BE0216_RS05065	COG0328	RNA-DNA hybrid ribonuclease activity
BE0216_RS05090	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BE0216_RS05095	COG0402	S-adenosylhomocysteine deaminase activity
BE0216_RS05105	COG0765	amino acid transport
BE0216_RS05110	COG1126	abc transporter atp-binding protein
BE0216_RS05115	COG0196	riboflavin kinase activity
BE0216_RS05175	COG2308	Evidence 4 Homologs of previously reported genes of
BE0216_RS05280	COG0255	Belongs to the universal ribosomal protein uL29 family
BE0216_RS05330	COG1012	belongs to the aldehyde dehydrogenase family
BE0216_RS05330	COG1454	alcohol dehydrogenase
BE0216_RS05345	COG0395	ABC-type sugar transport system, permease component
BE0216_RS05350	COG4209	transmembrane transport
BE0216_RS05355	COG0366	Alpha amylase catalytic
BE0216_RS05410	COG1739	Uncharacterized protein family UPF0029
BE0216_RS05415	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BE0216_RS05435	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BE0216_RS05450	COG0531	amino acid
BE0216_RS05455	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BE0216_RS05480	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BE0216_RS05485	COG0626	cystathionine gamma-synthase activity
BE0216_RS05495	COG0714	Associated with various cellular activities
BE0216_RS05515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BE0216_RS05555	COG3657	addiction module killer protein
BE0216_RS05575	COG0395	ABC-type sugar transport system, permease component
BE0216_RS05580	COG4209	transmembrane transport
BE0216_RS05590	COG1609	Transcriptional regulator
BE0216_RS05605	COG1373	ATPase (AAA superfamily
BE0216_RS05610	COG4989	oxidoreductase activity
BE0216_RS05640	COG0745	RESPONSE REGULATOR receiver
BE0216_RS05645	COG5002	protein histidine kinase activity
BE0216_RS05665	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BE0216_RS05670	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BE0216_RS05675	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BE0216_RS05680	COG2030	dehydratase
BE0216_RS05690	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BE0216_RS05700	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BE0216_RS05715	COG0673	inositol 2-dehydrogenase activity
BE0216_RS05730	COG1454	alcohol dehydrogenase
BE0216_RS05735	COG3579	cysteine-type endopeptidase activity
BE0216_RS05745	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BE0216_RS05760	COG0826	peptidase U32
BE0216_RS05770	COG0742	ribosomal rna small subunit methyltransferase
BE0216_RS05790	COG2270	Major facilitator Superfamily
BE0216_RS05795	COG2814	Major facilitator Superfamily
BE0216_RS05800	COG0477	Major facilitator Superfamily
BE0216_RS05835	COG3842	ATPase activity
BE0216_RS05870	COG0251	oxidation-reduction process
BE0216_RS05920	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BE0216_RS05955	COG0356	it plays a direct role in the translocation of protons across the membrane
BE0216_RS05990	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BE0216_RS06005	COG0745	RESPONSE REGULATOR receiver
BE0216_RS06015	COG4166	transmembrane transport
BE0216_RS06050	COG2801	Transposase and inactivated derivatives
BE0216_RS06065	COG1605	Chorismate mutase
BE0216_RS06065	COG0287	Prephenate dehydrogenase
BE0216_RS06070	COG4683	PFAM Phage derived protein Gp49-like (DUF891)
BE0216_RS06075	COG1396	sequence-specific DNA binding
BE0216_RS06145	COG1131	(ABC) transporter
BE0216_RS06170	COG1322	Protein conserved in bacteria
BE0216_RS06180	COG2217	Heavy metal translocating P-type atpase
BE0216_RS06185	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BE0216_RS06210	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BE0216_RS06255	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BE0216_RS06260	COG0406	alpha-ribazole phosphatase activity
BE0216_RS06260	COG0494	nUDIX hydrolase
BE0216_RS06270	COG1609	Transcriptional regulator
BE0216_RS06275	COG1653	transport
BE0216_RS06280	COG1175	transmembrane transport
BE0216_RS06285	COG0395	ABC-type sugar transport system, permease component
BE0216_RS06320	COG0584	glycerophosphoryl diester phosphodiesterase
BE0216_RS06335	COG0179	Fumarylacetoacetate (FAA) hydrolase
BE0216_RS06360	COG2801	Transposase and inactivated derivatives
BE0216_RS06405	COG0668	transmembrane transport
BE0216_RS06420	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BE0216_RS06425	COG0305	Participates in initiation and elongation during chromosome replication
BE0216_RS06430	COG0534	Mate efflux family protein
BE0216_RS06465	COG1215	transferase activity, transferring glycosyl groups
BE0216_RS06525	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS06550	COG1511	domain protein
BE0216_RS06560	COG1309	transcriptional regulator
BE0216_RS06575	COG0577	efflux transmembrane transporter activity
BE0216_RS06580	COG0577	efflux transmembrane transporter activity
BE0216_RS06595	COG0672	)-iron permease
BE0216_RS06605	COG1129	ABC transporter
BE0216_RS06625	COG0084	hydrolase, TatD family'
BE0216_RS06630	COG1609	Transcriptional regulator
BE0216_RS06660	COG3459	Glycosyltransferase 36 associated
BE0216_RS06675	COG1940	carbohydrate kinase activity
BE0216_RS06685	COG1609	Transcriptional regulator
BE0216_RS06695	COG3507	Belongs to the glycosyl hydrolase 43 family
BE0216_RS06700	COG1501	Belongs to the glycosyl hydrolase 31 family
BE0216_RS06705	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS06725	COG0395	ABC-type sugar transport system, permease component
BE0216_RS06730	COG4209	transmembrane transport
BE0216_RS06750	COG2211	Major facilitator Superfamily
BE0216_RS06760	COG1132	(ABC) transporter
BE0216_RS06775	COG1113	amino acid transport
BE0216_RS06805	COG2801	Transposase and inactivated derivatives
BE0216_RS06825	COG0477	Major facilitator Superfamily
BE0216_RS06840	COG1609	Transcriptional regulator
BE0216_RS06890	COG0191	fructose-bisphosphate aldolase activity
BE0216_RS06905	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BE0216_RS06915	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BE0216_RS06945	COG0667	Aldo Keto reductase
BE0216_RS06965	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BE0216_RS06970	COG0343	queuine tRNA-ribosyltransferase activity
BE0216_RS06985	COG2508	Transcriptional regulator
BE0216_RS06990	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BE0216_RS07000	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BE0216_RS07005	COG4521	taurine ABC transporter
BE0216_RS07010	COG4525	Part of the ABC transporter complex TauABC involved in taurine import. Responsible for energy coupling to the transport system
BE0216_RS07025	COG0697	spore germination
BE0216_RS07055	COG0768	penicillin binding
BE0216_RS07060	COG0515	serine threonine protein kinase
BE0216_RS07090	COG1940	carbohydrate kinase activity
BE0216_RS07095	COG1846	Transcriptional regulator
BE0216_RS07095	COG1940	carbohydrate kinase activity
BE0216_RS07150	COG1192	Involved in chromosome partitioning
BE0216_RS07195	COG1705	Flagellar rod assembly protein muramidase FlgJ
BE0216_RS07195	COG3942	CHAP domain
BE0216_RS07215	COG3550	peptidyl-serine autophosphorylation
BE0216_RS07245	COG3843	relaxase mobilization nuclease domain protein
BE0216_RS07275	COG4974	Belongs to the 'phage' integrase family
BE0216_RS07300	COG0058	SHG alpha-glucan phosphorylase activity
BE0216_RS07325	COG0180	Tryptophanyl-tRNA synthetase
BE0216_RS07355	COG4565	transcriptional regulatory protein
BE0216_RS07365	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BE0216_RS07370	COG0110	maltose O-acetyltransferase activity
BE0216_RS07400	COG1253	flavin adenine dinucleotide binding
BE0216_RS07405	COG0783	Belongs to the Dps family
BE0216_RS07425	COG1970	mechanosensitive ion channel activity
BE0216_RS07435	COG0477	Major facilitator Superfamily
BE0216_RS07440	COG2207	Transcriptional regulator
BE0216_RS07460	COG3279	Response regulator of the LytR AlgR family
BE0216_RS07465	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS07475	COG3279	Response regulator of the LytR AlgR family
BE0216_RS07480	COG1373	ATPase (AAA superfamily
BE0216_RS07490	COG0745	RESPONSE REGULATOR receiver
BE0216_RS07500	COG3550	peptidyl-serine autophosphorylation
BE0216_RS07515	COG0745	RESPONSE REGULATOR receiver
BE0216_RS07530	COG3250	beta-galactosidase activity
BE0216_RS07540	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS07550	COG3279	Response regulator of the LytR AlgR family
BE0216_RS07555	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BE0216_RS07600	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BE0216_RS07605	COG0187	DNA topoisomerase II activity
BE0216_RS07620	COG0592	DNA-directed DNA polymerase activity
BE0216_RS07650	COG1847	R3H domain protein
BE0216_RS07660	COG1192	Involved in chromosome partitioning
BE0216_RS07665	COG1475	DNA binding
BE0216_RS07685	COG0617	tRNA 3'-terminal CCA addition
BE0216_RS07705	COG3583	domain protein
BE0216_RS07770	COG1902	pentaerythritol trinitrate reductase activity
BE0216_RS07770	COG0446	pyridine nucleotide-disulphide oxidoreductase
BE0216_RS07810	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS07830	COG3842	ATPase activity
BE0216_RS07840	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BE0216_RS07850	COG1653	transport
BE0216_RS07855	COG4209	transmembrane transport
BE0216_RS07860	COG0395	ABC-type sugar transport system, permease component
BE0216_RS07870	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BE0216_RS07880	COG2801	Transposase and inactivated derivatives
BE0216_RS07890	COG0730	response to heat
BE0216_RS07895	COG0025	NhaP-type Na H and K H
BE0216_RS07900	COG0037	tRNA processing
BE0216_RS07900	COG0590	tRNA wobble adenosine to inosine editing
BE0216_RS07920	COG1175	transmembrane transport
BE0216_RS07930	COG0366	Alpha amylase catalytic
BE0216_RS07935	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BE0216_RS07940	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BE0216_RS07970	COG0406	alpha-ribazole phosphatase activity
BE0216_RS07980	COG1609	Transcriptional regulator
BE0216_RS07995	COG0366	Alpha amylase catalytic
BE0216_RS08020	COG1523	belongs to the glycosyl hydrolase 13 family
BE0216_RS08025	COG3833	ABC-type maltose transport systems, permease component
BE0216_RS08030	COG1175	transmembrane transport
BE0216_RS08040	COG0366	Alpha amylase catalytic
BE0216_RS08050	COG1609	Transcriptional regulator
BE0216_RS08055	COG1501	Belongs to the glycosyl hydrolase 31 family
BE0216_RS08075	COG0484	heat shock protein binding
BE0216_RS08080	COG0789	Transcriptional regulator
BE0216_RS08095	COG3534	alpha-L-arabinofuranosidase
BE0216_RS08135	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BE0216_RS08170	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BE0216_RS08175	COG0110	maltose O-acetyltransferase activity
BE0216_RS08235	COG0438	transferase activity, transferring glycosyl groups
BE0216_RS08240	COG1442	glycosyl transferase family 8
BE0216_RS08240	COG1216	Glycosyl transferase, family 2
BE0216_RS08245	COG1216	Glycosyl transferase, family 2
BE0216_RS08245	COG1442	glycosyl transferase family 8
BE0216_RS08275	COG1088	dTDP-glucose 4,6-dehydratase activity
BE0216_RS08290	COG0463	Glycosyl transferase, family 2
BE0216_RS08300	COG1216	Glycosyl transferase, family 2
BE0216_RS08315	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BE0216_RS08325	COG0463	Glycosyl transferase, family 2
BE0216_RS08330	COG1442	glycosyl transferase family 8
BE0216_RS08330	COG1216	Glycosyl transferase, family 2
BE0216_RS08350	COG1609	Transcriptional regulator
BE0216_RS08360	COG1175	transmembrane transport
BE0216_RS08365	COG0395	ABC-type sugar transport system, permease component
BE0216_RS08395	COG1404	Belongs to the peptidase S8 family
BE0216_RS08435	COG1309	transcriptional regulator
BE0216_RS08475	COG1940	carbohydrate kinase activity
BE0216_RS08480	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
BE0216_RS08485	COG0747	negative chemotaxis
BE0216_RS08495	COG0444	Belongs to the ABC transporter superfamily
BE0216_RS08500	COG4608	Belongs to the ABC transporter superfamily
BE0216_RS08505	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BE0216_RS08510	COG2186	Transcriptional regulator
BE0216_RS08530	COG3507	Belongs to the glycosyl hydrolase 43 family
BE0216_RS08535	COG3507	Belongs to the glycosyl hydrolase 43 family
BE0216_RS08545	COG1609	Transcriptional regulator
BE0216_RS08550	COG3940	Belongs to the glycosyl hydrolase 43 family
BE0216_RS08555	COG1653	transport
BE0216_RS08560	COG1175	transmembrane transport
BE0216_RS08565	COG0395	ABC-type sugar transport system, permease component
BE0216_RS08595	COG1754	DNA topoisomerase type I activity
BE0216_RS08595	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BE0216_RS08605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BE0216_RS08615	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BE0216_RS08670	COG3152	Membrane
BE0216_RS08675	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BE0216_RS08700	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BE0216_RS08705	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BE0216_RS08760	COG0167	dihydroorotate dehydrogenase activity
BE0216_RS08765	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BE0216_RS08775	COG1309	transcriptional regulator
BE0216_RS08790	COG2190	(PTS) system
BE0216_RS08790	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE0216_RS08790	COG1263	PTS System
BE0216_RS08795	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BE0216_RS08795	COG2190	(PTS) system
BE0216_RS08795	COG1263	PTS System
BE0216_RS08800	COG0460	homoserine dehydrogenase
BE0216_RS08805	COG0083	homoserine kinase activity
BE0216_RS08835	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BE0216_RS08840	COG1530	ribonuclease E activity
BE0216_RS08855	COG2801	Transposase and inactivated derivatives
BE0216_RS08915	COG0436	Aminotransferase
BE0216_RS08925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BE0216_RS08955	COG1268	BioY protein
BE0216_RS08960	COG4770	biotin carboxylase activity
BE0216_RS08965	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BE0216_RS08970	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BE0216_RS08975	COG1373	ATPase (AAA superfamily
BE0216_RS09015	COG1704	LemA family
BE0216_RS09040	COG0657	acetylesterase activity
BE0216_RS09055	COG0457	Tetratricopeptide repeat
BE0216_RS09060	COG1653	transport
BE0216_RS09070	COG0395	ABC-type sugar transport system, permease component
BE0216_RS09080	COG2207	Transcriptional regulator
BE0216_RS09080	COG0662	Cupin 2, conserved barrel domain protein
BE0216_RS09090	COG1874	Beta-galactosidase
BE0216_RS09100	COG0457	Tetratricopeptide repeat
BE0216_RS09105	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BE0216_RS09125	COG3119	arylsulfatase activity
BE0216_RS09125	COG3408	Glycogen debranching enzyme
BE0216_RS09150	COG1837	Belongs to the UPF0109 family
BE0216_RS09210	COG1132	(ABC) transporter
BE0216_RS09215	COG1132	(ABC) transporter
BE0216_RS09220	COG1609	Transcriptional regulator
BE0216_RS09385	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BE0216_RS09390	COG1609	Transcriptional regulator
BE0216_RS09415	COG1609	Transcriptional regulator
BE0216_RS09420	COG0477	Major facilitator Superfamily
BE0216_RS09425	COG0477	Major facilitator Superfamily
BE0216_RS09445	COG4988	ABC transporter
BE0216_RS09450	COG1653	transport
BE0216_RS09455	COG1175	transmembrane transport
BE0216_RS09460	COG0395	ABC-type sugar transport system, permease component
BE0216_RS09470	COG1609	Transcriptional regulator
BE0216_RS09475	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BE0216_RS09485	COG0656	L-ascorbic acid biosynthetic process
BE0216_RS09505	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BE0216_RS09520	COG0402	S-adenosylhomocysteine deaminase activity
BE0216_RS09545	COG1216	Glycosyl transferase, family 2
BE0216_RS09565	COG0438	transferase activity, transferring glycosyl groups
BE0216_RS09575	COG1216	Glycosyl transferase, family 2
BE0216_RS09595	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BE0216_RS09600	COG0489	protein tyrosine kinase activity
BE0216_RS09615	COG1216	Glycosyl transferase, family 2
BE0216_RS09630	COG1215	transferase activity, transferring glycosyl groups
BE0216_RS09675	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BE0216_RS09685	COG1442	glycosyl transferase family 8
BE0216_RS09685	COG1216	Glycosyl transferase, family 2
BE0216_RS09710	COG1216	Glycosyl transferase, family 2
BE0216_RS09715	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BE0216_RS09760	COG1653	transport
BE0216_RS09765	COG1175	transmembrane transport
BE0216_RS09770	COG0395	ABC-type sugar transport system, permease component
BE0216_RS09795	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BE0216_RS09880	COG1132	(ABC) transporter
BE0216_RS09885	COG2182	Extracellular solute-binding protein
BE0216_RS09890	COG1175	transmembrane transport
BE0216_RS09895	COG0395	ABC-type sugar transport system, permease component
BE0216_RS09905	COG1609	Transcriptional regulator
BE0216_RS09925	COG4124	Belongs to the glycosyl hydrolase 26 family
BE0216_RS09935	COG0095	Lipoate-protein ligase
BE0216_RS09945	COG4499	WXG100 protein secretion system (Wss), protein YukC
BE0216_RS09945	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BE0216_RS09950	COG1902	pentaerythritol trinitrate reductase activity
BE0216_RS09955	COG0167	dihydroorotate dehydrogenase activity
BE0216_RS09960	COG1349	DNA-binding transcription factor activity
BE0216_RS09970	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BE0216_RS09995	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BE0216_RS10010	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BE0216_RS10015	COG1194	a g-specific adenine glycosylase
BE0216_RS10045	COG0714	Associated with various cellular activities
BE0216_RS10085	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BE0216_RS10125	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BE0216_RS10130	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BE0216_RS10145	COG1946	Acyl-CoA thioesterase
BE0216_RS10170	COG3507	Belongs to the glycosyl hydrolase 43 family
BE0216_RS10185	COG1175	transmembrane transport
BE0216_RS10190	COG0395	ABC-type sugar transport system, permease component
BE0216_RS10195	COG3507	Belongs to the glycosyl hydrolase 43 family
BE0216_RS10215	COG1070	Carbohydrate kinase
BE0216_RS10250	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BE0216_RS10265	COG0366	Alpha amylase catalytic
BE0216_RS10270	COG1609	Transcriptional regulator
BE0216_RS10280	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BE0216_RS10295	COG0629	single-stranded DNA binding
BE0216_RS10300	COG3590	peptidase
BE0216_RS10310	COG0024	Methionine aminopeptidase
BE0216_RS10355	COG0395	ABC-type sugar transport system, permease component
BE0216_RS10375	COG0436	Aminotransferase
BE0216_RS10395	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BE0216_RS10400	COG1028	Short-chain dehydrogenase reductase Sdr
BE0216_RS10405	COG1722	exodeoxyribonuclease VII activity
BE0216_RS10410	COG1570	exodeoxyribonuclease VII activity
BE0216_RS10415	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BE0216_RS10415	COG1328	CTP reductase activity
BE0216_RS10420	COG0602	queuosine metabolic process
BE0216_RS10460	COG3226	Transcriptional regulator
BE0216_RS10480	COG3250	beta-galactosidase activity
BE0216_RS10485	COG1609	Transcriptional regulator
BE0216_RS10500	COG0395	ABC-type sugar transport system, permease component
BE0216_RS10525	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS10545	COG3507	Belongs to the glycosyl hydrolase 43 family
BE0216_RS10555	COG2197	response regulator
BE0216_RS10565	COG1373	ATPase (AAA superfamily
BE0216_RS10580	COG1487	ribonuclease activity
BE0216_RS10590	COG1309	transcriptional regulator
BE0216_RS10595	COG2801	Transposase and inactivated derivatives
BE0216_RS10635	COG1518	maintenance of DNA repeat elements
BE0216_RS10640	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BE0216_RS10675	COG1028	Short-chain dehydrogenase reductase Sdr
BE0216_RS10685	COG0673	inositol 2-dehydrogenase activity
BE0216_RS10690	COG1609	Transcriptional regulator
BE0216_RS10695	COG0477	Major facilitator Superfamily
BE0216_RS10700	COG3250	beta-galactosidase activity
BE0216_RS10705	COG2211	Major facilitator Superfamily
BE0216_RS10725	COG1309	transcriptional regulator
BE0216_RS10735	COG2211	Major facilitator Superfamily
BE0216_RS10745	COG1472	Belongs to the glycosyl hydrolase 3 family
BE0216_RS10755	COG1132	(ABC) transporter
BE0216_RS10760	COG1132	(ABC) transporter
BE0216_RS10785	COG1518	maintenance of DNA repeat elements
BE0216_RS10785	COG1468	defense response to virus
BE0216_RS10790	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BE0216_RS10820	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BE0216_RS10825	COG2205	protein histidine kinase activity
BE0216_RS10825	COG3292	Two component regulator propeller
BE0216_RS10825	COG0745	RESPONSE REGULATOR receiver
BE0216_RS10850	COG1063	alcohol dehydrogenase
BE0216_RS10865	COG0765	amino acid transport
BE0216_RS10870	COG0765	amino acid transport
BE0216_RS10875	COG1126	abc transporter atp-binding protein
BE0216_RS10880	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BE0216_RS10885	COG0436	Aminotransferase
BE0216_RS10890	COG1454	alcohol dehydrogenase
BE0216_RS10900	COG2011	ABC-type metal ion transport system permease component
BE0216_RS10905	COG1464	Belongs to the NlpA lipoprotein family
BE0216_RS10935	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BE0216_RS10945	COG0613	PHP domain protein
BE0216_RS10970	COG3480	Lon protease (S16) C-terminal proteolytic domain
BE0216_RS11030	COG0351	phosphomethylpyrimidine kinase
BE0216_RS11030	COG0352	thiamine-phosphate diphosphorylase activity
BE0216_RS11045	COG3579	cysteine-type endopeptidase activity
BE0216_RS11060	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BE0216_RS11090	COG0587	DNA-directed DNA polymerase activity
BE0216_RS11095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BE0216_RS11105	COG1136	(ABC) transporter
BE0216_RS11110	COG0577	efflux transmembrane transporter activity
BE0216_RS11160	COG0174	glutamine synthetase
BE0216_RS11165	COG2814	Major facilitator Superfamily
BE0216_RS11185	COG1131	(ABC) transporter
BE0216_RS11195	COG0789	Transcriptional regulator
BE0216_RS11205	COG1643	Atp-dependent helicase
BE0216_RS11210	COG2813	Specifically methylates the guanine in position
BE0216_RS11215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BE0216_RS11245	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BE0216_RS11270	COG0768	penicillin binding
BE0216_RS11280	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BE0216_RS11310	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BE0216_RS11340	COG1940	carbohydrate kinase activity
BE0216_RS11365	COG2182	Extracellular solute-binding protein
BE0216_RS11370	COG1175	transmembrane transport
BE0216_RS11375	COG0395	ABC-type sugar transport system, permease component
BE0216_RS11390	COG4166	transmembrane transport
BE0216_RS11395	COG0601	transmembrane transport
BE0216_RS11400	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BE0216_RS11405	COG4172	Belongs to the ABC transporter superfamily
BE0216_RS11415	COG0006	proline dipeptidase activity
BE0216_RS11420	COG0285	dihydrofolate synthase activity
BE0216_RS11425	COG1196	nuclear chromosome segregation
BE0216_RS11440	COG1595	DNA-templated transcription, initiation
BE0216_RS11475	COG4721	ABC-type cobalt transport system, permease component
BE0216_RS11490	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BE0216_RS11520	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BE0216_RS11530	COG0477	Major facilitator Superfamily
BE0216_RS11535	COG1217	gtp-binding protein TYPA
BE0216_RS11550	COG0287	Prephenate dehydrogenase
BE0216_RS11570	COG4166	transmembrane transport
BE0216_RS11575	COG0601	transmembrane transport
BE0216_RS11580	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BE0216_RS11590	COG0708	Exodeoxyribonuclease III
BE0216_RS11620	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BE0216_RS11625	COG0110	maltose O-acetyltransferase activity
BE0216_RS11630	COG2207	Transcriptional regulator
BE0216_RS11630	COG1917	Cupin 2, conserved barrel domain protein
BE0216_RS11660	COG1335	isochorismatase
BE0216_RS11670	COG2197	response regulator
BE0216_RS11685	COG0670	Belongs to the BI1 family
BE0216_RS11695	COG2357	RelA SpoT domain protein
BE0216_RS11730	COG1396	sequence-specific DNA binding
BE0216_RS11755	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BE0216_RS11765	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BE0216_RS11770	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BE0216_RS11775	COG0800	Aldolase
BE0216_RS11780	COG1609	Transcriptional regulator
BE0216_RS11790	COG1175	transmembrane transport
BE0216_RS11795	COG0395	ABC-type sugar transport system, permease component
BE0216_RS11815	COG0246	Mannitol dehydrogenase
BE0216_RS11825	COG1904	glucuronate isomerase
BE0216_RS11835	COG1609	Transcriptional regulator
BE0216_RS11840	COG1609	Transcriptional regulator
BE0216_RS11850	COG4225	unsaturated rhamnogalacturonyl hydrolase activity
BE0216_RS11855	COG1028	Short-chain dehydrogenase reductase Sdr
BE0216_RS11880	COG0395	ABC-type sugar transport system, permease component