locus-tag	class	description
FVF69_RS00230	COG4974	Belongs to the 'phage' integrase family
FVF69_RS00315	COG0045	succinate-CoA ligase (ADP-forming) activity
FVF69_RS00340	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FVF69_RS00345	COG1187	pseudouridine synthase activity
FVF69_RS00405	COG1716	ATPase activity
FVF69_RS00425	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
FVF69_RS00440	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
FVF69_RS00455	COG0133	tryptophan synthase activity
FVF69_RS00525	COG1131	(ABC) transporter
FVF69_RS00530	COG0745	RESPONSE REGULATOR receiver
FVF69_RS00555	COG1131	(ABC) transporter
FVF69_RS00565	COG2197	response regulator
FVF69_RS00570	COG4585	Histidine kinase
FVF69_RS00580	COG0577	efflux transmembrane transporter activity
FVF69_RS00580	COG1136	(ABC) transporter
FVF69_RS00620	COG0706	membrane insertase activity
FVF69_RS00630	COG0833	amino acid
FVF69_RS00635	COG0681	Belongs to the peptidase S26 family
FVF69_RS00670	COG0583	DNA-binding transcription factor activity
FVF69_RS00685	COG0167	dihydroorotate dehydrogenase activity
FVF69_RS00690	COG0543	2 iron, 2 sulfur cluster binding
FVF69_RS00695	COG0284	orotidine-5'-phosphate decarboxylase activity
FVF69_RS00700	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FVF69_RS00735	COG0588	phosphoglycerate mutase activity
FVF69_RS00760	COG4989	oxidoreductase activity
FVF69_RS00770	COG1063	alcohol dehydrogenase
FVF69_RS00820	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVF69_RS00825	COG0561	phosphatase activity
FVF69_RS00830	COG1119	ATPase activity
FVF69_RS00835	COG0297	glycogen (starch) synthase activity
FVF69_RS00850	COG4166	transmembrane transport
FVF69_RS00860	COG0070	glutamate synthase
FVF69_RS00860	COG0067	glutamate synthase
FVF69_RS00860	COG0069	glutamate synthase activity
FVF69_RS00875	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
FVF69_RS00890	COG1609	Transcriptional regulator
FVF69_RS00915	COG1929	Belongs to the glycerate kinase type-1 family
FVF69_RS00940	COG2860	membrane
FVF69_RS00950	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
FVF69_RS00980	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
FVF69_RS01005	COG1702	phosphate starvation-inducible protein PhoH
FVF69_RS01010	COG0537	adenosine 5'-monophosphoramidase activity
FVF69_RS01015	COG1385	rRNA (uridine-N3-)-methyltransferase activity
FVF69_RS01035	COG2151	metal-sulfur cluster biosynthetic enzyme
FVF69_RS01050	COG0396	ATPase activity
FVF69_RS01055	COG0719	Fe-S assembly protein
FVF69_RS01085	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
FVF69_RS01130	COG0588	phosphoglycerate mutase activity
FVF69_RS01135	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FVF69_RS01135	COG2755	lipolytic protein G-D-S-L family
FVF69_RS01145	COG1136	(ABC) transporter
FVF69_RS01145	COG0577	efflux transmembrane transporter activity
FVF69_RS01175	COG3655	Transcriptional regulator
FVF69_RS01225	COG1131	(ABC) transporter
FVF69_RS01230	COG4585	Histidine kinase
FVF69_RS01235	COG2197	response regulator
FVF69_RS01245	COG0306	phosphate transporter
FVF69_RS01255	COG1966	Carbon starvation protein
FVF69_RS01265	COG1309	transcriptional regulator
FVF69_RS01270	COG0513	Belongs to the DEAD box helicase family
FVF69_RS01275	COG2233	PERMEase
FVF69_RS01315	COG2815	serine threonine protein kinase
FVF69_RS01315	COG0515	serine threonine protein kinase
FVF69_RS01330	COG2814	Major facilitator Superfamily
FVF69_RS01560	COG1475	DNA binding
FVF69_RS01625	COG4974	Belongs to the 'phage' integrase family
FVF69_RS01630	COG0012	GTP binding
FVF69_RS01635	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
FVF69_RS01645	COG4585	Histidine kinase
FVF69_RS01650	COG2197	response regulator
FVF69_RS01655	COG1136	(ABC) transporter
FVF69_RS01655	COG0577	efflux transmembrane transporter activity
FVF69_RS01660	COG1136	(ABC) transporter
FVF69_RS01665	COG2873	o-acetylhomoserine
FVF69_RS01685	COG0758	DNA mediated transformation
FVF69_RS01690	COG1053	succinate dehydrogenase
FVF69_RS01705	COG1611	Belongs to the LOG family
FVF69_RS01765	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
FVF69_RS01770	COG1882	Formate acetyltransferase
FVF69_RS01785	COG1473	amidohydrolase
FVF69_RS01790	COG2011	ABC-type metal ion transport system permease component
FVF69_RS01865	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
FVF69_RS01865	COG2755	lipolytic protein G-D-S-L family
FVF69_RS01885	COG0799	negative regulation of ribosome biogenesis
FVF69_RS01890	COG0406	alpha-ribazole phosphatase activity
FVF69_RS01905	COG0280	phosphate acetyltransferase
FVF69_RS01905	COG0857	belongs to the CobB CobQ family
FVF69_RS01910	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
FVF69_RS01950	COG3250	beta-galactosidase activity
FVF69_RS01960	COG0519	Catalyzes the synthesis of GMP from XMP
FVF69_RS01980	COG1051	belongs to the nudix hydrolase family
FVF69_RS01985	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
FVF69_RS02005	COG0494	nUDIX hydrolase
FVF69_RS02010	COG0469	pyruvate kinase activity
FVF69_RS02030	COG0539	negative regulation of cytoplasmic translation
FVF69_RS02040	COG0803	Belongs to the bacterial solute-binding protein 9 family
FVF69_RS02045	COG1121	(ABC) transporter
FVF69_RS02060	COG1329	Transcriptional regulator
FVF69_RS02070	COG0745	RESPONSE REGULATOR receiver
FVF69_RS02075	COG2205	protein histidine kinase activity
FVF69_RS02085	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
FVF69_RS02115	COG1316	TRANSCRIPTIONal
FVF69_RS02145	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
FVF69_RS02155	COG1760	l-serine dehydratase
FVF69_RS02185	COG0667	Aldo Keto reductase
FVF69_RS02200	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FVF69_RS02200	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
FVF69_RS02215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
FVF69_RS02245	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FVF69_RS02260	COG1131	(ABC) transporter
FVF69_RS02270	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FVF69_RS02275	COG0497	DNA recombination
FVF69_RS02285	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
FVF69_RS02290	COG0569	domain protein
FVF69_RS02330	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
FVF69_RS02335	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
FVF69_RS02410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FVF69_RS02420	COG1122	ATPase activity
FVF69_RS02425	COG4721	ABC-type cobalt transport system, permease component
FVF69_RS02430	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FVF69_RS02455	COG3250	beta-galactosidase activity
FVF69_RS02465	COG0110	maltose O-acetyltransferase activity
FVF69_RS02470	COG0110	maltose O-acetyltransferase activity
FVF69_RS02490	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
FVF69_RS02535	COG1063	alcohol dehydrogenase
FVF69_RS02560	COG0583	DNA-binding transcription factor activity
FVF69_RS02595	COG0385	Bile acid
FVF69_RS02625	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
FVF69_RS02655	COG0667	Aldo Keto reductase
FVF69_RS02665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FVF69_RS02670	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
FVF69_RS02675	COG0402	S-adenosylhomocysteine deaminase activity
FVF69_RS02685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVF69_RS02715	COG1012	belongs to the aldehyde dehydrogenase family
FVF69_RS02740	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
FVF69_RS02745	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
FVF69_RS02755	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
FVF69_RS02760	COG0577	efflux transmembrane transporter activity
FVF69_RS02760	COG1136	(ABC) transporter
FVF69_RS02770	COG1136	(ABC) transporter
FVF69_RS02770	COG0577	efflux transmembrane transporter activity
FVF69_RS02785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
FVF69_RS02800	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
FVF69_RS02810	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
FVF69_RS02825	COG3655	Transcriptional regulator
FVF69_RS02835	COG0358	DNA primase activity
FVF69_RS02845	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
FVF69_RS02850	COG0531	amino acid
FVF69_RS02865	COG0514	ATP-dependent DNA helicase (RecQ)
FVF69_RS02875	COG0626	cystathionine gamma-synthase activity
FVF69_RS02890	COG4608	Belongs to the ABC transporter superfamily
FVF69_RS02900	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVF69_RS02905	COG0601	transmembrane transport
FVF69_RS02910	COG0747	negative chemotaxis
FVF69_RS02925	COG1653	transport
FVF69_RS02930	COG1653	transport
FVF69_RS02935	COG3534	alpha-L-arabinofuranosidase
FVF69_RS02950	COG0395	ABC-type sugar transport system, permease component
FVF69_RS02955	COG1175	transmembrane transport
FVF69_RS02975	COG3550	peptidyl-serine autophosphorylation
FVF69_RS02980	COG0564	pseudouridine synthase activity
FVF69_RS03015	COG1388	LysM domain
FVF69_RS03015	COG3942	CHAP domain
FVF69_RS03020	COG2177	Part of the ABC transporter FtsEX involved in
FVF69_RS03025	COG2884	Cell division ATP-binding protein ftsE
FVF69_RS03030	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
FVF69_RS03070	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
FVF69_RS03110	COG0714	Associated with various cellular activities
FVF69_RS03155	COG1194	a g-specific adenine glycosylase
FVF69_RS03160	COG0463	Glycosyl transferase, family 2
FVF69_RS03170	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
FVF69_RS03190	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
FVF69_RS03200	COG1349	DNA-binding transcription factor activity
FVF69_RS03210	COG0167	dihydroorotate dehydrogenase activity
FVF69_RS03215	COG1902	pentaerythritol trinitrate reductase activity
FVF69_RS03220	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FVF69_RS03220	COG4499	WXG100 protein secretion system (Wss), protein YukC
FVF69_RS03230	COG0095	Lipoate-protein ligase
FVF69_RS03290	COG0489	protein tyrosine kinase activity
FVF69_RS03430	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
FVF69_RS03435	COG0463	Glycosyl transferase, family 2
FVF69_RS03455	COG0438	transferase activity, transferring glycosyl groups
FVF69_RS03460	COG0438	transferase activity, transferring glycosyl groups
FVF69_RS03465	COG2826	transposase and inactivated derivatives, IS30 family
FVF69_RS03475	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FVF69_RS03490	COG2814	Major facilitator Superfamily
FVF69_RS03510	COG0656	L-ascorbic acid biosynthetic process
FVF69_RS03550	COG2814	Major facilitator Superfamily
FVF69_RS03555	COG1132	(ABC) transporter
FVF69_RS03580	COG0577	efflux transmembrane transporter activity
FVF69_RS03590	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
FVF69_RS03615	COG1609	Transcriptional regulator
FVF69_RS03620	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
FVF69_RS03640	COG1116	anion transmembrane transporter activity
FVF69_RS03730	COG2348	transferase activity, transferring amino-acyl groups
FVF69_RS03770	COG0667	Aldo Keto reductase
FVF69_RS03800	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
FVF69_RS03845	COG0440	acetolactate synthase activity
FVF69_RS03860	COG0488	(ABC) transporter
FVF69_RS03865	COG0505	Belongs to the CarA family
FVF69_RS03900	COG1837	Belongs to the UPF0109 family
FVF69_RS03910	COG1957	nucleoside hydrolase
FVF69_RS03925	COG1704	LemA family
FVF69_RS03950	COG0745	RESPONSE REGULATOR receiver
FVF69_RS03955	COG5002	protein histidine kinase activity
FVF69_RS03960	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
FVF69_RS03965	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FVF69_RS03970	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
FVF69_RS03975	COG3579	cysteine-type endopeptidase activity
FVF69_RS03985	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
FVF69_RS03995	COG1496	oxidoreductase activity
FVF69_RS04000	COG0826	peptidase U32
FVF69_RS04010	COG0742	ribosomal rna small subunit methyltransferase
FVF69_RS04025	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
FVF69_RS04025	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
FVF69_RS04030	COG2270	Major facilitator Superfamily
FVF69_RS04060	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
FVF69_RS04075	COG1027	Aspartate ammonia-lyase
FVF69_RS04090	COG3842	ATPase activity
FVF69_RS04125	COG0251	oxidation-reduction process
FVF69_RS04160	COG0545	Peptidyl-prolyl cis-trans isomerase
FVF69_RS04170	COG0355	proton-transporting ATP synthase activity, rotational mechanism
FVF69_RS04205	COG0356	it plays a direct role in the translocation of protons across the membrane
FVF69_RS04260	COG4974	Belongs to the 'phage' integrase family
FVF69_RS04275	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
FVF69_RS04290	COG0745	RESPONSE REGULATOR receiver
FVF69_RS04315	COG1605	Chorismate mutase
FVF69_RS04315	COG0287	Prephenate dehydrogenase
FVF69_RS04365	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FVF69_RS04375	COG1322	Protein conserved in bacteria
FVF69_RS04380	COG1937	Protein conserved in bacteria
FVF69_RS04390	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
FVF69_RS04395	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
FVF69_RS04400	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
FVF69_RS04440	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
FVF69_RS04465	COG0395	ABC-type sugar transport system, permease component
FVF69_RS04470	COG1175	transmembrane transport
FVF69_RS04480	COG1609	Transcriptional regulator
FVF69_RS04495	COG3442	glutamine amidotransferase
FVF69_RS04500	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FVF69_RS04505	COG0305	Participates in initiation and elongation during chromosome replication
FVF69_RS04515	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
FVF69_RS04535	COG1309	transcriptional regulator
FVF69_RS04540	COG1215	transferase activity, transferring glycosyl groups
FVF69_RS04565	COG0363	glucosamine-6-phosphate deaminase activity
FVF69_RS04570	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
FVF69_RS04600	COG1136	(ABC) transporter
FVF69_RS04605	COG0577	efflux transmembrane transporter activity
FVF69_RS04620	COG3470	protein probably involved in high-affinity Fe2 transport
FVF69_RS04625	COG0672	)-iron permease
FVF69_RS04640	COG3619	membrane
FVF69_RS04645	COG0366	Alpha amylase catalytic
FVF69_RS04685	COG0676	glucose-6-phosphate 1-epimerase activity
FVF69_RS04740	COG1754	DNA topoisomerase type I activity
FVF69_RS04740	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
FVF69_RS04760	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
FVF69_RS04790	COG0527	aspartate kinase activity
FVF69_RS04880	COG0586	Pfam SNARE associated Golgi protein
FVF69_RS04885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
FVF69_RS04890	COG1028	Short-chain dehydrogenase reductase Sdr
FVF69_RS04910	COG0789	Transcriptional regulator
FVF69_RS04940	COG0395	ABC-type sugar transport system, permease component
FVF69_RS04945	COG1609	Transcriptional regulator
FVF69_RS04970	COG0366	Alpha amylase catalytic
FVF69_RS04990	COG0477	Major facilitator Superfamily
FVF69_RS05030	COG4974	Belongs to the 'phage' integrase family
FVF69_RS05050	COG3534	alpha-L-arabinofuranosidase
FVF69_RS05085	COG0191	fructose-bisphosphate aldolase activity
FVF69_RS05125	COG0343	queuine tRNA-ribosyltransferase activity
FVF69_RS05190	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
FVF69_RS05215	COG0071	Belongs to the small heat shock protein (HSP20) family
FVF69_RS05280	COG0768	penicillin binding
FVF69_RS05285	COG0515	serine threonine protein kinase
FVF69_RS05325	COG0058	SHG alpha-glucan phosphorylase activity
FVF69_RS05340	COG0180	Tryptophanyl-tRNA synthetase
FVF69_RS05345	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
FVF69_RS05355	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
FVF69_RS05365	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
FVF69_RS05405	COG1253	flavin adenine dinucleotide binding
FVF69_RS05410	COG0783	Belongs to the Dps family
FVF69_RS05420	COG3265	gluconokinase activity
FVF69_RS05430	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
FVF69_RS05435	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
FVF69_RS05480	COG0436	Aminotransferase
FVF69_RS05485	COG1522	sequence-specific DNA binding
FVF69_RS05490	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
FVF69_RS05500	COG0542	response to heat
FVF69_RS05510	COG3266	domain, Protein
FVF69_RS05515	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FVF69_RS05520	COG0187	DNA topoisomerase II activity
FVF69_RS05535	COG0592	DNA-directed DNA polymerase activity
FVF69_RS05580	COG1192	Involved in chromosome partitioning
FVF69_RS05585	COG1475	DNA binding
FVF69_RS05590	COG3328	transposase activity
FVF69_RS05595	COG0395	ABC-type sugar transport system, permease component
FVF69_RS05600	COG1175	transmembrane transport
FVF69_RS05610	COG1609	Transcriptional regulator
FVF69_RS05615	COG0366	Alpha amylase catalytic
FVF69_RS05655	COG0617	tRNA 3'-terminal CCA addition
FVF69_RS05675	COG3583	domain protein
FVF69_RS05710	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
FVF69_RS05725	COG1472	Belongs to the glycosyl hydrolase 3 family
FVF69_RS05745	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
FVF69_RS05755	COG1215	transferase activity, transferring glycosyl groups
FVF69_RS05760	COG3842	ATPase activity
FVF69_RS05770	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
FVF69_RS05785	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
FVF69_RS05815	COG0025	NhaP-type Na H and K H
FVF69_RS05820	COG0037	tRNA processing
FVF69_RS05820	COG0590	tRNA wobble adenosine to inosine editing
FVF69_RS05845	COG1175	transmembrane transport
FVF69_RS05850	COG0395	ABC-type sugar transport system, permease component
FVF69_RS05855	COG1609	Transcriptional regulator
FVF69_RS05860	COG1609	Transcriptional regulator
FVF69_RS05890	COG0395	ABC-type sugar transport system, permease component
FVF69_RS05895	COG0366	Alpha amylase catalytic
FVF69_RS05905	COG0366	Alpha amylase catalytic
FVF69_RS05910	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
FVF69_RS05915	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
FVF69_RS05970	COG0778	Nitroreductase
FVF69_RS05980	COG0588	phosphoglycerate mutase activity
FVF69_RS05985	COG2182	Extracellular solute-binding protein
FVF69_RS05990	COG1609	Transcriptional regulator
FVF69_RS06035	COG1113	amino acid transport
FVF69_RS06055	COG1113	amino acid transport
FVF69_RS06075	COG3645	SOS response
FVF69_RS06080	COG1846	Transcriptional regulator
FVF69_RS06100	COG1132	(ABC) transporter
FVF69_RS06180	COG1609	Transcriptional regulator
FVF69_RS06195	COG1132	(ABC) transporter
FVF69_RS06200	COG1132	(ABC) transporter
FVF69_RS06210	COG0084	hydrolase, TatD family'
FVF69_RS06230	COG1129	ABC transporter
FVF69_RS06260	COG0463	Glycosyl transferase, family 2
FVF69_RS06290	COG0438	transferase activity, transferring glycosyl groups
FVF69_RS06290	COG1216	Glycosyl transferase, family 2
FVF69_RS06295	COG1088	dTDP-glucose 4,6-dehydratase activity
FVF69_RS06310	COG1215	transferase activity, transferring glycosyl groups
FVF69_RS06350	COG1216	Glycosyl transferase, family 2
FVF69_RS06350	COG1442	glycosyl transferase family 8
FVF69_RS06365	COG0179	Fumarylacetoacetate (FAA) hydrolase
FVF69_RS06375	COG2986	histidine ammonia-lyase
FVF69_RS06390	COG0584	glycerophosphoryl diester phosphodiesterase
FVF69_RS06420	COG0494	nUDIX hydrolase
FVF69_RS06420	COG0406	alpha-ribazole phosphatase activity
FVF69_RS06425	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
FVF69_RS06460	COG0167	dihydroorotate dehydrogenase activity
FVF69_RS06465	COG0446	pyridine nucleotide-disulphide oxidoreductase
FVF69_RS06470	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
FVF69_RS06490	COG1309	transcriptional regulator
FVF69_RS06505	COG0460	homoserine dehydrogenase
FVF69_RS06510	COG0083	homoserine kinase activity
FVF69_RS06535	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
FVF69_RS06540	COG1530	ribonuclease E activity
FVF69_RS06565	COG0436	Aminotransferase
FVF69_RS06575	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FVF69_RS06580	COG0250	Participates in transcription elongation, termination and antitermination
FVF69_RS06645	COG1268	BioY protein
FVF69_RS06650	COG4770	biotin carboxylase activity
FVF69_RS06655	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
FVF69_RS06730	COG2252	PERMEase
FVF69_RS06825	COG0812	UDP-N-acetylmuramate dehydrogenase activity
FVF69_RS06830	COG0531	amino acid
FVF69_RS06845	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
FVF69_RS06865	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FVF69_RS06870	COG1739	Uncharacterized protein family UPF0029
FVF69_RS06905	COG1012	belongs to the aldehyde dehydrogenase family
FVF69_RS06905	COG1454	alcohol dehydrogenase
FVF69_RS06960	COG0255	Belongs to the universal ribosomal protein uL29 family
FVF69_RS07070	COG2308	Evidence 4 Homologs of previously reported genes of
FVF69_RS07120	COG0196	riboflavin kinase activity
FVF69_RS07145	COG0328	RNA-DNA hybrid ribonuclease activity
FVF69_RS07155	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
FVF69_RS07190	COG3711	transcriptional antiterminator
FVF69_RS07195	COG1597	lipid kinase activity
FVF69_RS07195	COG1803	Methylglyoxal synthase
FVF69_RS07220	COG1175	transmembrane transport
FVF69_RS07225	COG0395	ABC-type sugar transport system, permease component
FVF69_RS07250	COG2197	response regulator
FVF69_RS07285	COG2814	Major facilitator Superfamily
FVF69_RS07295	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
FVF69_RS07300	COG1575	Belongs to the MenA family. Type 1 subfamily
FVF69_RS07310	COG0704	Plays a role in the regulation of phosphate uptake
FVF69_RS07315	COG5002	protein histidine kinase activity
FVF69_RS07325	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
FVF69_RS07330	COG1705	Flagellar rod assembly protein muramidase FlgJ
FVF69_RS07330	COG3942	CHAP domain
FVF69_RS07340	COG0791	NLP P60 protein
FVF69_RS07345	COG0589	response to stress
FVF69_RS07365	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
FVF69_RS07370	COG1687	branched-chain amino acid
FVF69_RS07375	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
FVF69_RS07390	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
FVF69_RS07410	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
FVF69_RS07420	COG1454	alcohol dehydrogenase
FVF69_RS07460	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
FVF69_RS07465	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
FVF69_RS07475	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
FVF69_RS07480	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
FVF69_RS07490	COG1946	Acyl-CoA thioesterase
FVF69_RS07510	COG1940	carbohydrate kinase activity
FVF69_RS07515	COG1129	ABC transporter
FVF69_RS07535	COG4214	carbohydrate transport
FVF69_RS07550	COG2814	Major facilitator Superfamily
FVF69_RS07560	COG0242	peptide deformylase activity
FVF69_RS07570	COG2814	Major facilitator Superfamily
FVF69_RS07575	COG2814	Major facilitator Superfamily
FVF69_RS07590	COG4211	Belongs to the binding-protein-dependent transport system permease family
FVF69_RS07605	COG1070	Carbohydrate kinase
FVF69_RS07660	COG0110	maltose O-acetyltransferase activity
FVF69_RS07665	COG0009	L-threonylcarbamoyladenylate synthase
FVF69_RS07670	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
FVF69_RS07685	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
FVF69_RS07690	COG1355	regulation of microtubule-based process
FVF69_RS07720	COG3590	peptidase
FVF69_RS07775	COG0436	Aminotransferase
FVF69_RS07780	COG0248	Ppx GppA phosphatase
FVF69_RS07810	COG1970	mechanosensitive ion channel activity
FVF69_RS07815	COG1022	Amp-dependent synthetase and ligase
FVF69_RS07820	COG2249	NAD(P)H dehydrogenase (quinone) activity
FVF69_RS07825	COG1722	exodeoxyribonuclease VII activity
FVF69_RS07830	COG1570	exodeoxyribonuclease VII activity
FVF69_RS07835	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
FVF69_RS07835	COG1328	CTP reductase activity
FVF69_RS07840	COG0602	queuosine metabolic process
FVF69_RS07855	COG1309	transcriptional regulator
FVF69_RS07905	COG1132	(ABC) transporter
FVF69_RS07910	COG1132	(ABC) transporter
FVF69_RS07925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVF69_RS07935	COG1609	Transcriptional regulator
FVF69_RS07940	COG3250	beta-galactosidase activity
FVF69_RS07945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
FVF69_RS07975	COG1715	Restriction endonuclease
FVF69_RS07995	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
FVF69_RS08025	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
FVF69_RS08030	COG0560	Phosphoserine phosphatase
FVF69_RS08035	COG0586	Pfam SNARE associated Golgi protein
FVF69_RS08075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
FVF69_RS08130	COG0714	Associated with various cellular activities
FVF69_RS08145	COG1278	Cold shock
FVF69_RS08165	COG0745	RESPONSE REGULATOR receiver
FVF69_RS08170	COG2205	protein histidine kinase activity
FVF69_RS08175	COG1278	Cold shock
FVF69_RS08185	COG0589	response to stress
FVF69_RS08195	COG0402	S-adenosylhomocysteine deaminase activity
FVF69_RS08205	COG0477	Major facilitator Superfamily
FVF69_RS08210	COG1402	creatininase
FVF69_RS08220	COG1196	nuclear chromosome segregation
FVF69_RS08245	COG1126	abc transporter atp-binding protein
FVF69_RS08250	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVF69_RS08255	COG0765	amino acid transport
FVF69_RS08260	COG0765	amino acid transport
FVF69_RS08280	COG2326	polyphosphate kinase activity
FVF69_RS08285	COG4581	dead DEAH box helicase
FVF69_RS08295	COG0745	RESPONSE REGULATOR receiver
FVF69_RS08330	COG2814	Major facilitator Superfamily
FVF69_RS08335	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FVF69_RS08390	COG1122	ATPase activity
FVF69_RS08440	COG0395	ABC-type sugar transport system, permease component
FVF69_RS08455	COG1501	Belongs to the glycosyl hydrolase 31 family
FVF69_RS08460	COG1250	3-hydroxyacyl-CoA dehydrogenase
FVF69_RS08485	COG1376	ErfK ybiS ycfS ynhG family protein
FVF69_RS08490	COG0390	transport system, permease component
FVF69_RS08495	COG1136	(ABC) transporter
FVF69_RS08520	COG0284	orotidine-5'-phosphate decarboxylase activity
FVF69_RS08535	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
FVF69_RS08550	COG0765	amino acid transport
FVF69_RS08555	COG1126	abc transporter atp-binding protein
FVF69_RS08560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVF69_RS08595	COG2873	o-acetylhomoserine
FVF69_RS08600	COG2873	o-acetylhomoserine
FVF69_RS08625	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
FVF69_RS08660	COG3480	Lon protease (S16) C-terminal proteolytic domain
FVF69_RS08705	COG1957	nucleoside hydrolase
FVF69_RS08715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
FVF69_RS08755	COG2271	Major facilitator Superfamily
FVF69_RS08765	COG0351	phosphomethylpyrimidine kinase
FVF69_RS08765	COG0352	thiamine-phosphate diphosphorylase activity
FVF69_RS08800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
FVF69_RS08835	COG1373	ATPase (AAA superfamily
FVF69_RS08850	COG0587	DNA-directed DNA polymerase activity
FVF69_RS08860	COG4716	Myosin-crossreactive antigen
FVF69_RS08885	COG0656	L-ascorbic acid biosynthetic process
FVF69_RS08935	COG0174	glutamine synthetase
FVF69_RS08950	COG1643	Atp-dependent helicase
FVF69_RS08955	COG2813	Specifically methylates the guanine in position
FVF69_RS08965	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
FVF69_RS08995	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
FVF69_RS09020	COG0768	penicillin binding
FVF69_RS09030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
FVF69_RS09070	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
FVF69_RS09100	COG1175	transmembrane transport
FVF69_RS09105	COG0395	ABC-type sugar transport system, permease component
FVF69_RS09115	COG1472	Belongs to the glycosyl hydrolase 3 family
FVF69_RS09160	COG1940	carbohydrate kinase activity
FVF69_RS09165	COG1940	carbohydrate kinase activity
FVF69_RS09180	COG4166	transmembrane transport
FVF69_RS09185	COG0601	transmembrane transport
FVF69_RS09205	COG0006	proline dipeptidase activity
FVF69_RS09220	COG0285	dihydrofolate synthase activity
FVF69_RS09225	COG1196	nuclear chromosome segregation
FVF69_RS09240	COG1595	DNA-templated transcription, initiation
FVF69_RS09250	COG2017	converts alpha-aldose to the beta-anomer
FVF69_RS09255	COG2017	converts alpha-aldose to the beta-anomer
FVF69_RS09265	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
FVF69_RS09285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
FVF69_RS09305	COG0577	efflux transmembrane transporter activity
FVF69_RS09305	COG1136	(ABC) transporter
FVF69_RS09315	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
FVF69_RS09320	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
FVF69_RS09330	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
FVF69_RS09335	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
FVF69_RS09345	COG1104	cysteine desulfurase activity
FVF69_RS09350	COG0477	Major facilitator Superfamily
FVF69_RS09355	COG1217	gtp-binding protein TYPA
FVF69_RS09365	COG0077	Prephenate dehydratase
FVF69_RS09365	COG1605	Chorismate mutase
FVF69_RS09370	COG0287	Prephenate dehydrogenase
FVF69_RS09385	COG4166	transmembrane transport
FVF69_RS09390	COG0601	transmembrane transport
FVF69_RS09395	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
FVF69_RS09405	COG0708	Exodeoxyribonuclease III
FVF69_RS09460	COG2197	response regulator
FVF69_RS09475	COG0670	Belongs to the BI1 family
FVF69_RS09485	COG2357	RelA SpoT domain protein
FVF69_RS09515	COG1058	Belongs to the CinA family
FVF69_RS09515	COG1546	Belongs to the CinA family
FVF69_RS09520	COG1396	sequence-specific DNA binding
FVF69_RS09545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
FVF69_RS09565	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
FVF69_RS09590	COG0142	geranyltranstransferase activity
FVF69_RS09600	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
FVF69_RS09605	COG0187	DNA topoisomerase II activity
FVF69_RS09615	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
FVF69_RS09620	COG1201	RNA secondary structure unwinding
FVF69_RS09630	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
FVF69_RS09655	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
FVF69_RS09660	COG2801	Transposase and inactivated derivatives
FVF69_RS09695	COG0406	alpha-ribazole phosphatase activity
FVF69_RS09700	COG0598	Magnesium transport protein CorA
FVF69_RS09705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
FVF69_RS09715	COG1555	photosystem II stabilization
FVF69_RS09715	COG1596	polysaccharide export
FVF69_RS09725	COG1228	amidohydrolase
FVF69_RS09740	COG0456	acetyltransferase
FVF69_RS09780	COG0516	GMP reductase activity
FVF69_RS09820	COG0575	Belongs to the CDS family
FVF69_RS09830	COG0693	protein deglycase activity
FVF69_RS09855	COG0488	(ABC) transporter
FVF69_RS09860	COG1028	Short-chain dehydrogenase reductase Sdr
FVF69_RS09875	COG1129	ABC transporter
FVF69_RS09925	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
FVF69_RS09950	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
FVF69_RS09965	COG0436	Aminotransferase
FVF69_RS09980	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway