locus-tag	class	description
H8S96_RS00010	COG0592	DNA-directed DNA polymerase activity
H8S96_RS00025	COG0187	DNA topoisomerase II activity
H8S96_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H8S96_RS00035	COG3266	domain, Protein
H8S96_RS00040	COG2826	transposase and inactivated derivatives, IS30 family
H8S96_RS00050	COG4677	pectinesterase activity
H8S96_RS00055	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
H8S96_RS00060	COG1522	sequence-specific DNA binding
H8S96_RS00065	COG0436	Aminotransferase
H8S96_RS00100	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
H8S96_RS00105	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
H8S96_RS00115	COG3265	gluconokinase activity
H8S96_RS00135	COG0783	Belongs to the Dps family
H8S96_RS00140	COG1253	flavin adenine dinucleotide binding
H8S96_RS00170	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
H8S96_RS00180	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
H8S96_RS00195	COG0180	Tryptophanyl-tRNA synthetase
H8S96_RS00210	COG0058	SHG alpha-glucan phosphorylase activity
H8S96_RS00255	COG4584	PFAM Integrase catalytic
H8S96_RS00275	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
H8S96_RS00280	COG1088	dTDP-glucose 4,6-dehydratase activity
H8S96_RS00305	COG0179	Fumarylacetoacetate (FAA) hydrolase
H8S96_RS00320	COG2986	histidine ammonia-lyase
H8S96_RS00335	COG0584	glycerophosphoryl diester phosphodiesterase
H8S96_RS00360	COG0494	nUDIX hydrolase
H8S96_RS00360	COG0406	alpha-ribazole phosphatase activity
H8S96_RS00365	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
H8S96_RS00390	COG0167	dihydroorotate dehydrogenase activity
H8S96_RS00395	COG0446	pyridine nucleotide-disulphide oxidoreductase
H8S96_RS00400	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
H8S96_RS00420	COG1309	transcriptional regulator
H8S96_RS00435	COG0460	homoserine dehydrogenase
H8S96_RS00440	COG0083	homoserine kinase activity
H8S96_RS00465	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H8S96_RS00470	COG1530	ribonuclease E activity
H8S96_RS00495	COG0436	Aminotransferase
H8S96_RS00505	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H8S96_RS00510	COG0250	Participates in transcription elongation, termination and antitermination
H8S96_RS00565	COG1268	BioY protein
H8S96_RS00570	COG4770	biotin carboxylase activity
H8S96_RS00575	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
H8S96_RS00665	COG3507	Belongs to the glycosyl hydrolase 43 family
H8S96_RS00670	COG3507	Belongs to the glycosyl hydrolase 43 family
H8S96_RS00690	COG2252	PERMEase
H8S96_RS00785	COG0812	UDP-N-acetylmuramate dehydrogenase activity
H8S96_RS00790	COG0531	amino acid
H8S96_RS00805	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H8S96_RS00825	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H8S96_RS00830	COG1739	Uncharacterized protein family UPF0029
H8S96_RS00865	COG1454	alcohol dehydrogenase
H8S96_RS00865	COG1012	belongs to the aldehyde dehydrogenase family
H8S96_RS00920	COG0255	Belongs to the universal ribosomal protein uL29 family
H8S96_RS01025	COG2308	Evidence 4 Homologs of previously reported genes of
H8S96_RS01040	COG3534	alpha-L-arabinofuranosidase
H8S96_RS01075	COG0196	riboflavin kinase activity
H8S96_RS01100	COG0328	RNA-DNA hybrid ribonuclease activity
H8S96_RS01110	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
H8S96_RS01140	COG3711	transcriptional antiterminator
H8S96_RS01145	COG1597	lipid kinase activity
H8S96_RS01145	COG1803	Methylglyoxal synthase
H8S96_RS01175	COG1175	transmembrane transport
H8S96_RS01180	COG0395	ABC-type sugar transport system, permease component
H8S96_RS01205	COG2197	response regulator
H8S96_RS01240	COG2814	Major facilitator Superfamily
H8S96_RS01250	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
H8S96_RS01255	COG1575	Belongs to the MenA family. Type 1 subfamily
H8S96_RS01265	COG0704	Plays a role in the regulation of phosphate uptake
H8S96_RS01270	COG5002	protein histidine kinase activity
H8S96_RS01280	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
H8S96_RS01285	COG3942	CHAP domain
H8S96_RS01285	COG1705	Flagellar rod assembly protein muramidase FlgJ
H8S96_RS01300	COG0589	response to stress
H8S96_RS01320	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H8S96_RS01325	COG1687	branched-chain amino acid
H8S96_RS01330	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
H8S96_RS01345	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
H8S96_RS01360	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
H8S96_RS01365	COG1454	alcohol dehydrogenase
H8S96_RS01405	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
H8S96_RS01410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
H8S96_RS01420	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
H8S96_RS01425	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
H8S96_RS01435	COG1946	Acyl-CoA thioesterase
H8S96_RS01450	COG1940	carbohydrate kinase activity
H8S96_RS01455	COG1129	ABC transporter
H8S96_RS01475	COG4214	carbohydrate transport
H8S96_RS01490	COG2814	Major facilitator Superfamily
H8S96_RS01500	COG0242	peptide deformylase activity
H8S96_RS01510	COG2814	Major facilitator Superfamily
H8S96_RS01515	COG2814	Major facilitator Superfamily
H8S96_RS01525	COG1979	alcohol dehydrogenase
H8S96_RS01530	COG1609	Transcriptional regulator
H8S96_RS01540	COG1175	transmembrane transport
H8S96_RS01545	COG0395	ABC-type sugar transport system, permease component
H8S96_RS01550	COG3507	Belongs to the glycosyl hydrolase 43 family
H8S96_RS01555	COG3507	Belongs to the glycosyl hydrolase 43 family
H8S96_RS01585	COG1070	Carbohydrate kinase
H8S96_RS01640	COG0110	maltose O-acetyltransferase activity
H8S96_RS01645	COG0009	L-threonylcarbamoyladenylate synthase
H8S96_RS01650	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
H8S96_RS01665	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
H8S96_RS01670	COG1355	regulation of microtubule-based process
H8S96_RS01695	COG3590	peptidase
H8S96_RS01750	COG0436	Aminotransferase
H8S96_RS01755	COG0248	Ppx GppA phosphatase
H8S96_RS01780	COG1970	mechanosensitive ion channel activity
H8S96_RS01785	COG1022	Amp-dependent synthetase and ligase
H8S96_RS01790	COG2249	NAD(P)H dehydrogenase (quinone) activity
H8S96_RS01795	COG1722	exodeoxyribonuclease VII activity
H8S96_RS01800	COG1570	exodeoxyribonuclease VII activity
H8S96_RS01805	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
H8S96_RS01805	COG1328	CTP reductase activity
H8S96_RS01810	COG0602	queuosine metabolic process
H8S96_RS01865	COG1132	(ABC) transporter
H8S96_RS01870	COG1132	(ABC) transporter
H8S96_RS01895	COG1122	ATPase activity
H8S96_RS01900	COG0135	phosphoribosylanthranilate isomerase activity
H8S96_RS01905	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H8S96_RS01915	COG0546	phosphoglycolate phosphatase activity
H8S96_RS01920	COG1979	alcohol dehydrogenase
H8S96_RS01925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H8S96_RS01935	COG1609	Transcriptional regulator
H8S96_RS01940	COG3250	beta-galactosidase activity
H8S96_RS01945	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
H8S96_RS01985	COG1518	maintenance of DNA repeat elements
H8S96_RS01990	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
H8S96_RS02005	COG2801	Transposase and inactivated derivatives
H8S96_RS02075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
H8S96_RS02080	COG0560	Phosphoserine phosphatase
H8S96_RS02085	COG0586	Pfam SNARE associated Golgi protein
H8S96_RS02125	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
H8S96_RS02175	COG0714	Associated with various cellular activities
H8S96_RS02190	COG1278	Cold shock
H8S96_RS02210	COG0745	RESPONSE REGULATOR receiver
H8S96_RS02215	COG2205	protein histidine kinase activity
H8S96_RS02220	COG1278	Cold shock
H8S96_RS02230	COG0589	response to stress
H8S96_RS02240	COG0402	S-adenosylhomocysteine deaminase activity
H8S96_RS02250	COG0477	Major facilitator Superfamily
H8S96_RS02255	COG1402	creatininase
H8S96_RS02265	COG1196	nuclear chromosome segregation
H8S96_RS02285	COG1126	abc transporter atp-binding protein
H8S96_RS02290	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H8S96_RS02295	COG0765	amino acid transport
H8S96_RS02300	COG0765	amino acid transport
H8S96_RS02320	COG2326	polyphosphate kinase activity
H8S96_RS02325	COG4581	dead DEAH box helicase
H8S96_RS02335	COG0745	RESPONSE REGULATOR receiver
H8S96_RS02370	COG2814	Major facilitator Superfamily
H8S96_RS02375	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H8S96_RS02430	COG1122	ATPase activity
H8S96_RS02465	COG0395	ABC-type sugar transport system, permease component
H8S96_RS02480	COG1501	Belongs to the glycosyl hydrolase 31 family
H8S96_RS02485	COG1250	3-hydroxyacyl-CoA dehydrogenase
H8S96_RS02510	COG1376	ErfK ybiS ycfS ynhG family protein
H8S96_RS02515	COG0390	transport system, permease component
H8S96_RS02520	COG1136	(ABC) transporter
H8S96_RS02520	COG0577	efflux transmembrane transporter activity
H8S96_RS02545	COG0284	orotidine-5'-phosphate decarboxylase activity
H8S96_RS02560	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
H8S96_RS02575	COG0765	amino acid transport
H8S96_RS02580	COG1126	abc transporter atp-binding protein
H8S96_RS02585	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H8S96_RS02590	COG0626	cystathionine gamma-synthase activity
H8S96_RS02615	COG2873	o-acetylhomoserine
H8S96_RS02635	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
H8S96_RS02670	COG3480	Lon protease (S16) C-terminal proteolytic domain
H8S96_RS02715	COG1957	nucleoside hydrolase
H8S96_RS02725	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
H8S96_RS02755	COG2271	Major facilitator Superfamily
H8S96_RS02765	COG0352	thiamine-phosphate diphosphorylase activity
H8S96_RS02765	COG0351	phosphomethylpyrimidine kinase
H8S96_RS02795	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
H8S96_RS02825	COG1373	ATPase (AAA superfamily
H8S96_RS02840	COG0587	DNA-directed DNA polymerase activity
H8S96_RS02850	COG4716	Myosin-crossreactive antigen
H8S96_RS02875	COG0656	L-ascorbic acid biosynthetic process
H8S96_RS02930	COG0174	glutamine synthetase
H8S96_RS02945	COG1643	Atp-dependent helicase
H8S96_RS02950	COG2813	Specifically methylates the guanine in position
H8S96_RS02955	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
H8S96_RS02985	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
H8S96_RS03010	COG0768	penicillin binding
H8S96_RS03020	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H8S96_RS03090	COG1175	transmembrane transport
H8S96_RS03095	COG0395	ABC-type sugar transport system, permease component
H8S96_RS03105	COG1472	Belongs to the glycosyl hydrolase 3 family
H8S96_RS03155	COG1940	carbohydrate kinase activity
H8S96_RS03175	COG4166	transmembrane transport
H8S96_RS03180	COG0601	transmembrane transport
H8S96_RS03200	COG0006	proline dipeptidase activity
H8S96_RS03210	COG0285	dihydrofolate synthase activity
H8S96_RS03215	COG1196	nuclear chromosome segregation
H8S96_RS03230	COG1595	DNA-templated transcription, initiation
H8S96_RS03240	COG2017	converts alpha-aldose to the beta-anomer
H8S96_RS03245	COG2017	converts alpha-aldose to the beta-anomer
H8S96_RS03280	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
H8S96_RS03300	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
H8S96_RS03320	COG1136	(ABC) transporter
H8S96_RS03320	COG0577	efflux transmembrane transporter activity
H8S96_RS03330	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
H8S96_RS03335	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
H8S96_RS03345	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
H8S96_RS03350	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
H8S96_RS03360	COG1104	cysteine desulfurase activity
H8S96_RS03365	COG0477	Major facilitator Superfamily
H8S96_RS03370	COG1217	gtp-binding protein TYPA
H8S96_RS03380	COG0077	Prephenate dehydratase
H8S96_RS03380	COG1605	Chorismate mutase
H8S96_RS03385	COG0287	Prephenate dehydrogenase
H8S96_RS03400	COG4166	transmembrane transport
H8S96_RS03405	COG0601	transmembrane transport
H8S96_RS03410	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H8S96_RS03420	COG0708	Exodeoxyribonuclease III
H8S96_RS03475	COG2197	response regulator
H8S96_RS03490	COG0670	Belongs to the BI1 family
H8S96_RS03500	COG2357	RelA SpoT domain protein
H8S96_RS03530	COG1058	Belongs to the CinA family
H8S96_RS03530	COG1546	Belongs to the CinA family
H8S96_RS03535	COG1396	sequence-specific DNA binding
H8S96_RS03560	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
H8S96_RS03575	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
H8S96_RS03595	COG0142	geranyltranstransferase activity
H8S96_RS03605	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
H8S96_RS03610	COG0187	DNA topoisomerase II activity
H8S96_RS03620	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
H8S96_RS03625	COG1201	RNA secondary structure unwinding
H8S96_RS03635	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
H8S96_RS03660	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
H8S96_RS03665	COG2801	Transposase and inactivated derivatives
H8S96_RS03700	COG0406	alpha-ribazole phosphatase activity
H8S96_RS03705	COG0598	Magnesium transport protein CorA
H8S96_RS03710	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H8S96_RS03720	COG1555	photosystem II stabilization
H8S96_RS03720	COG1596	polysaccharide export
H8S96_RS03730	COG1228	amidohydrolase
H8S96_RS03740	COG0802	atpase or kinase
H8S96_RS03750	COG0456	acetyltransferase
H8S96_RS03790	COG0516	GMP reductase activity
H8S96_RS03830	COG0575	Belongs to the CDS family
H8S96_RS03840	COG0693	protein deglycase activity
H8S96_RS03865	COG0488	(ABC) transporter
H8S96_RS03870	COG1028	Short-chain dehydrogenase reductase Sdr
H8S96_RS03885	COG1129	ABC transporter
H8S96_RS03900	COG2826	transposase and inactivated derivatives, IS30 family
H8S96_RS03940	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
H8S96_RS03965	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
H8S96_RS03975	COG0561	phosphatase activity
H8S96_RS03980	COG0436	Aminotransferase
H8S96_RS03995	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
H8S96_RS04095	COG0045	succinate-CoA ligase (ADP-forming) activity
H8S96_RS04120	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H8S96_RS04125	COG1187	pseudouridine synthase activity
H8S96_RS04280	COG1803	Methylglyoxal synthase
H8S96_RS04295	COG1716	ATPase activity
H8S96_RS04315	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
H8S96_RS04330	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
H8S96_RS04345	COG0133	tryptophan synthase activity
H8S96_RS04405	COG1131	(ABC) transporter
H8S96_RS04435	COG1131	(ABC) transporter
H8S96_RS04445	COG2197	response regulator
H8S96_RS04450	COG4585	Histidine kinase
H8S96_RS04460	COG1136	(ABC) transporter
H8S96_RS04460	COG0577	efflux transmembrane transporter activity
H8S96_RS04500	COG0706	membrane insertase activity
H8S96_RS04510	COG0833	amino acid
H8S96_RS04515	COG0681	Belongs to the peptidase S26 family
H8S96_RS04550	COG0583	DNA-binding transcription factor activity
H8S96_RS04570	COG0167	dihydroorotate dehydrogenase activity
H8S96_RS04575	COG0543	2 iron, 2 sulfur cluster binding
H8S96_RS04580	COG0284	orotidine-5'-phosphate decarboxylase activity
H8S96_RS04585	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
H8S96_RS04610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
H8S96_RS04620	COG0588	phosphoglycerate mutase activity
H8S96_RS04635	COG4989	oxidoreductase activity
H8S96_RS04645	COG1063	alcohol dehydrogenase
H8S96_RS04715	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
H8S96_RS04725	COG0561	phosphatase activity
H8S96_RS04725	COG0561	phosphatase activity
H8S96_RS04730	COG1119	ATPase activity
H8S96_RS04735	COG0297	glycogen (starch) synthase activity
H8S96_RS04750	COG4166	transmembrane transport
H8S96_RS04770	COG0067	glutamate synthase
H8S96_RS04770	COG0070	glutamate synthase
H8S96_RS04770	COG0069	glutamate synthase activity
H8S96_RS04780	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
H8S96_RS04810	COG1929	Belongs to the glycerate kinase type-1 family
H8S96_RS04835	COG2860	membrane
H8S96_RS04845	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
H8S96_RS04870	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
H8S96_RS04895	COG1702	phosphate starvation-inducible protein PhoH
H8S96_RS04900	COG0537	adenosine 5'-monophosphoramidase activity
H8S96_RS04905	COG1385	rRNA (uridine-N3-)-methyltransferase activity
H8S96_RS04925	COG2151	metal-sulfur cluster biosynthetic enzyme
H8S96_RS04935	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
H8S96_RS04940	COG0396	ATPase activity
H8S96_RS04945	COG0719	Fe-S assembly protein
H8S96_RS04970	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
H8S96_RS05015	COG0588	phosphoglycerate mutase activity
H8S96_RS05020	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H8S96_RS05020	COG2755	lipolytic protein G-D-S-L family
H8S96_RS05030	COG0577	efflux transmembrane transporter activity
H8S96_RS05030	COG1136	(ABC) transporter
H8S96_RS05060	COG3655	Transcriptional regulator
H8S96_RS05105	COG1131	(ABC) transporter
H8S96_RS05110	COG4585	Histidine kinase
H8S96_RS05115	COG2197	response regulator
H8S96_RS05125	COG0306	phosphate transporter
H8S96_RS05135	COG1966	Carbon starvation protein
H8S96_RS05145	COG1309	transcriptional regulator
H8S96_RS05150	COG0513	Belongs to the DEAD box helicase family
H8S96_RS05155	COG2233	PERMEase
H8S96_RS05195	COG0515	serine threonine protein kinase
H8S96_RS05195	COG2815	serine threonine protein kinase
H8S96_RS05205	COG2814	Major facilitator Superfamily
H8S96_RS05235	COG0012	GTP binding
H8S96_RS05240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
H8S96_RS05250	COG4585	Histidine kinase
H8S96_RS05255	COG2197	response regulator
H8S96_RS05260	COG1136	(ABC) transporter
H8S96_RS05260	COG0577	efflux transmembrane transporter activity
H8S96_RS05265	COG1136	(ABC) transporter
H8S96_RS05270	COG2873	o-acetylhomoserine
H8S96_RS05290	COG0758	DNA mediated transformation
H8S96_RS05295	COG1053	succinate dehydrogenase
H8S96_RS05310	COG1611	Belongs to the LOG family
H8S96_RS05370	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
H8S96_RS05375	COG1882	Formate acetyltransferase
H8S96_RS05390	COG1473	amidohydrolase
H8S96_RS05395	COG2011	ABC-type metal ion transport system permease component
H8S96_RS05480	COG2755	lipolytic protein G-D-S-L family
H8S96_RS05480	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
H8S96_RS05500	COG0799	negative regulation of ribosome biogenesis
H8S96_RS05505	COG0406	alpha-ribazole phosphatase activity
H8S96_RS05520	COG0280	phosphate acetyltransferase
H8S96_RS05520	COG0857	belongs to the CobB CobQ family
H8S96_RS05525	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
H8S96_RS05575	COG3250	beta-galactosidase activity
H8S96_RS05605	COG1051	belongs to the nudix hydrolase family
H8S96_RS05610	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
H8S96_RS05630	COG0494	nUDIX hydrolase
H8S96_RS05635	COG0469	pyruvate kinase activity
H8S96_RS05655	COG0539	negative regulation of cytoplasmic translation
H8S96_RS05665	COG0803	Belongs to the bacterial solute-binding protein 9 family
H8S96_RS05670	COG1121	(ABC) transporter
H8S96_RS05685	COG1329	Transcriptional regulator
H8S96_RS05695	COG0745	RESPONSE REGULATOR receiver
H8S96_RS05700	COG2205	protein histidine kinase activity
H8S96_RS05710	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
H8S96_RS05745	COG1316	TRANSCRIPTIONal
H8S96_RS05775	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
H8S96_RS05785	COG1760	l-serine dehydratase
H8S96_RS05820	COG0667	Aldo Keto reductase
H8S96_RS05835	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
H8S96_RS05835	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H8S96_RS05850	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
H8S96_RS05875	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H8S96_RS05890	COG1131	(ABC) transporter
H8S96_RS05900	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H8S96_RS05905	COG0497	DNA recombination
H8S96_RS05915	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
H8S96_RS05920	COG0569	domain protein
H8S96_RS05965	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
H8S96_RS05970	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
H8S96_RS06045	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H8S96_RS06055	COG1122	ATPase activity
H8S96_RS06060	COG4721	ABC-type cobalt transport system, permease component
H8S96_RS06065	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
H8S96_RS06090	COG3250	beta-galactosidase activity
H8S96_RS06100	COG0110	maltose O-acetyltransferase activity
H8S96_RS06105	COG0110	maltose O-acetyltransferase activity
H8S96_RS06120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
H8S96_RS06150	COG1063	alcohol dehydrogenase
H8S96_RS06205	COG0385	Bile acid
H8S96_RS06235	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
H8S96_RS06265	COG0667	Aldo Keto reductase
H8S96_RS06275	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
H8S96_RS06280	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
H8S96_RS06285	COG0402	S-adenosylhomocysteine deaminase activity
H8S96_RS06295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
H8S96_RS06325	COG1012	belongs to the aldehyde dehydrogenase family
H8S96_RS06350	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
H8S96_RS06355	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
H8S96_RS06365	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
H8S96_RS06370	COG1136	(ABC) transporter
H8S96_RS06370	COG0577	efflux transmembrane transporter activity
H8S96_RS06380	COG0577	efflux transmembrane transporter activity
H8S96_RS06380	COG1136	(ABC) transporter
H8S96_RS06395	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
H8S96_RS06410	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
H8S96_RS06420	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
H8S96_RS06435	COG3655	Transcriptional regulator
H8S96_RS06445	COG0358	DNA primase activity
H8S96_RS06455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
H8S96_RS06460	COG0531	amino acid
H8S96_RS06485	COG0514	ATP-dependent DNA helicase (RecQ)
H8S96_RS06495	COG0626	cystathionine gamma-synthase activity
H8S96_RS06505	COG4608	Belongs to the ABC transporter superfamily
H8S96_RS06515	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
H8S96_RS06520	COG0601	transmembrane transport
H8S96_RS06525	COG0747	negative chemotaxis
H8S96_RS06540	COG1653	transport
H8S96_RS06545	COG1653	transport
H8S96_RS06550	COG3534	alpha-L-arabinofuranosidase
H8S96_RS06565	COG0395	ABC-type sugar transport system, permease component
H8S96_RS06570	COG1175	transmembrane transport
H8S96_RS06590	COG0564	pseudouridine synthase activity
H8S96_RS06625	COG3942	CHAP domain
H8S96_RS06625	COG1388	LysM domain
H8S96_RS06630	COG2177	Part of the ABC transporter FtsEX involved in
H8S96_RS06635	COG2884	Cell division ATP-binding protein ftsE
H8S96_RS06640	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
H8S96_RS06680	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
H8S96_RS06720	COG0714	Associated with various cellular activities
H8S96_RS06765	COG1194	a g-specific adenine glycosylase
H8S96_RS06770	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
H8S96_RS06785	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H8S96_RS06810	COG0297	glycogen (starch) synthase activity
H8S96_RS06810	COG0438	transferase activity, transferring glycosyl groups
H8S96_RS06840	COG1442	glycosyl transferase family 8
H8S96_RS06840	COG1216	Glycosyl transferase, family 2
H8S96_RS06845	COG1216	Glycosyl transferase, family 2
H8S96_RS06850	COG0438	transferase activity, transferring glycosyl groups
H8S96_RS06855	COG1216	Glycosyl transferase, family 2
H8S96_RS06855	COG1442	glycosyl transferase family 8
H8S96_RS06865	COG1216	Glycosyl transferase, family 2
H8S96_RS06880	COG0438	transferase activity, transferring glycosyl groups
H8S96_RS06890	COG0438	transferase activity, transferring glycosyl groups
H8S96_RS06895	COG0110	maltose O-acetyltransferase activity
H8S96_RS06900	COG0438	transferase activity, transferring glycosyl groups
H8S96_RS06920	COG1621	beta-fructofuranosidase activity
H8S96_RS06935	COG0395	ABC-type sugar transport system, permease component
H8S96_RS06940	COG4209	transmembrane transport
H8S96_RS06955	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
H8S96_RS06965	COG1349	DNA-binding transcription factor activity
H8S96_RS06970	COG0167	dihydroorotate dehydrogenase activity
H8S96_RS06975	COG1902	pentaerythritol trinitrate reductase activity
H8S96_RS06980	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H8S96_RS06980	COG4499	WXG100 protein secretion system (Wss), protein YukC
H8S96_RS06990	COG0095	Lipoate-protein ligase
H8S96_RS07030	COG3118	belongs to the thioredoxin family
H8S96_RS07030	COG0492	ferredoxin-NADP+ reductase activity
H8S96_RS07065	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
H8S96_RS07160	COG2814	Major facilitator Superfamily
H8S96_RS07175	COG0656	L-ascorbic acid biosynthetic process
H8S96_RS07190	COG2814	Major facilitator Superfamily
H8S96_RS07220	COG0577	efflux transmembrane transporter activity
H8S96_RS07230	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
H8S96_RS07255	COG1609	Transcriptional regulator
H8S96_RS07260	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
H8S96_RS07280	COG1116	anion transmembrane transporter activity
H8S96_RS07355	COG0667	Aldo Keto reductase
H8S96_RS07395	COG0440	acetolactate synthase activity
H8S96_RS07410	COG0488	(ABC) transporter
H8S96_RS07415	COG0505	Belongs to the CarA family
H8S96_RS07445	COG1837	Belongs to the UPF0109 family
H8S96_RS07455	COG1957	nucleoside hydrolase
H8S96_RS07470	COG1704	LemA family
H8S96_RS07495	COG0745	RESPONSE REGULATOR receiver
H8S96_RS07500	COG5002	protein histidine kinase activity
H8S96_RS07505	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
H8S96_RS07510	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H8S96_RS07515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
H8S96_RS07520	COG3579	cysteine-type endopeptidase activity
H8S96_RS07530	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
H8S96_RS07540	COG1496	oxidoreductase activity
H8S96_RS07545	COG0826	peptidase U32
H8S96_RS07555	COG0742	ribosomal rna small subunit methyltransferase
H8S96_RS07570	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
H8S96_RS07570	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
H8S96_RS07595	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
H8S96_RS07610	COG1027	Aspartate ammonia-lyase
H8S96_RS07625	COG3842	ATPase activity
H8S96_RS07660	COG0251	oxidation-reduction process
H8S96_RS07690	COG0545	Peptidyl-prolyl cis-trans isomerase
H8S96_RS07700	COG0355	proton-transporting ATP synthase activity, rotational mechanism
H8S96_RS07735	COG0356	it plays a direct role in the translocation of protons across the membrane
H8S96_RS07790	COG4974	Belongs to the 'phage' integrase family
H8S96_RS07810	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
H8S96_RS07825	COG0745	RESPONSE REGULATOR receiver
H8S96_RS07850	COG1605	Chorismate mutase
H8S96_RS07850	COG0287	Prephenate dehydrogenase
H8S96_RS07900	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H8S96_RS07910	COG1322	Protein conserved in bacteria
H8S96_RS07915	COG1937	Protein conserved in bacteria
H8S96_RS07925	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
H8S96_RS07930	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
H8S96_RS07935	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
H8S96_RS07975	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
H8S96_RS07995	COG0395	ABC-type sugar transport system, permease component
H8S96_RS08000	COG1175	transmembrane transport
H8S96_RS08010	COG1609	Transcriptional regulator
H8S96_RS08025	COG3442	glutamine amidotransferase
H8S96_RS08030	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
H8S96_RS08035	COG0305	Participates in initiation and elongation during chromosome replication
H8S96_RS08045	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
H8S96_RS08065	COG1309	transcriptional regulator
H8S96_RS08070	COG1215	transferase activity, transferring glycosyl groups
H8S96_RS08095	COG0363	glucosamine-6-phosphate deaminase activity
H8S96_RS08100	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
H8S96_RS08130	COG1136	(ABC) transporter
H8S96_RS08135	COG0577	efflux transmembrane transporter activity
H8S96_RS08150	COG3470	protein probably involved in high-affinity Fe2 transport
H8S96_RS08155	COG0672	)-iron permease
H8S96_RS08170	COG3619	membrane
H8S96_RS08175	COG0366	Alpha amylase catalytic
H8S96_RS08205	COG0676	glucose-6-phosphate 1-epimerase activity
H8S96_RS08260	COG1754	DNA topoisomerase type I activity
H8S96_RS08260	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
H8S96_RS08275	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
H8S96_RS08310	COG0527	aspartate kinase activity
H8S96_RS08390	COG0586	Pfam SNARE associated Golgi protein
H8S96_RS08395	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
H8S96_RS08400	COG1028	Short-chain dehydrogenase reductase Sdr
H8S96_RS08445	COG0395	ABC-type sugar transport system, permease component
H8S96_RS08450	COG1609	Transcriptional regulator
H8S96_RS08475	COG0366	Alpha amylase catalytic
H8S96_RS08490	COG0477	Major facilitator Superfamily
H8S96_RS08545	COG3534	alpha-L-arabinofuranosidase
H8S96_RS08580	COG0191	fructose-bisphosphate aldolase activity
H8S96_RS08605	COG2217	Heavy metal translocating P-type atpase
H8S96_RS08615	COG0343	queuine tRNA-ribosyltransferase activity
H8S96_RS08640	COG1216	Glycosyl transferase, family 2
H8S96_RS08660	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
H8S96_RS08680	COG0071	Belongs to the small heat shock protein (HSP20) family
H8S96_RS08745	COG0768	penicillin binding
H8S96_RS08750	COG0515	serine threonine protein kinase
H8S96_RS08775	COG2226	methyltransferase
H8S96_RS08800	COG1442	glycosyl transferase family 8
H8S96_RS08820	COG1442	glycosyl transferase family 8
H8S96_RS08830	COG1088	dTDP-glucose 4,6-dehydratase activity
H8S96_RS08850	COG1129	ABC transporter
H8S96_RS08870	COG0084	hydrolase, TatD family'
H8S96_RS08880	COG0395	ABC-type sugar transport system, permease component
H8S96_RS08885	COG1175	transmembrane transport
H8S96_RS08895	COG3940	Belongs to the glycosyl hydrolase 43 family
H8S96_RS08905	COG1609	Transcriptional regulator
H8S96_RS08915	COG3507	Belongs to the glycosyl hydrolase 43 family
H8S96_RS08920	COG3507	Belongs to the glycosyl hydrolase 43 family
H8S96_RS08935	COG1132	(ABC) transporter
H8S96_RS08940	COG1132	(ABC) transporter
H8S96_RS08950	COG1609	Transcriptional regulator
H8S96_RS09015	COG1132	(ABC) transporter
H8S96_RS09025	COG1846	Transcriptional regulator
H8S96_RS09030	COG3645	SOS response
H8S96_RS09050	COG1113	amino acid transport
H8S96_RS09060	COG1136	(ABC) transporter
H8S96_RS09060	COG0577	efflux transmembrane transporter activity
H8S96_RS09070	COG1113	amino acid transport
H8S96_RS09075	COG3507	Belongs to the glycosyl hydrolase 43 family
H8S96_RS09115	COG1609	Transcriptional regulator
H8S96_RS09120	COG2182	Extracellular solute-binding protein
H8S96_RS09125	COG0588	phosphoglycerate mutase activity
H8S96_RS09135	COG0778	Nitroreductase
H8S96_RS09145	COG1511	domain protein
H8S96_RS09185	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
H8S96_RS09190	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
H8S96_RS09195	COG0366	Alpha amylase catalytic
H8S96_RS09205	COG0366	Alpha amylase catalytic
H8S96_RS09210	COG0395	ABC-type sugar transport system, permease component
H8S96_RS09235	COG1609	Transcriptional regulator
H8S96_RS09240	COG1609	Transcriptional regulator
H8S96_RS09245	COG0395	ABC-type sugar transport system, permease component
H8S96_RS09250	COG1175	transmembrane transport
H8S96_RS09270	COG0590	tRNA wobble adenosine to inosine editing
H8S96_RS09270	COG0037	tRNA processing
H8S96_RS09275	COG0025	NhaP-type Na H and K H
H8S96_RS09300	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
H8S96_RS09315	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
H8S96_RS09330	COG3842	ATPase activity
H8S96_RS09335	COG1216	Glycosyl transferase, family 2
H8S96_RS09345	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
H8S96_RS09370	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
H8S96_RS09395	COG3583	domain protein
H8S96_RS09415	COG0617	tRNA 3'-terminal CCA addition
H8S96_RS09445	COG1475	DNA binding
H8S96_RS09450	COG1192	Involved in chromosome partitioning