locus-tag	class	description
GS08_RS00015	COG0592	DNA-directed DNA polymerase activity
GS08_RS00030	COG0187	DNA topoisomerase II activity
GS08_RS00035	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GS08_RS00040	COG3266	domain, Protein
GS08_RS00045	COG0542	response to heat
GS08_RS00050	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GS08_RS00055	COG1522	sequence-specific DNA binding
GS08_RS00060	COG0436	Aminotransferase
GS08_RS00110	COG3265	gluconokinase activity
GS08_RS00120	COG0783	Belongs to the Dps family
GS08_RS00125	COG1253	flavin adenine dinucleotide binding
GS08_RS00135	COG1716	ATPase activity
GS08_RS00135	COG1131	(ABC) transporter
GS08_RS00135	COG0842	Transport permease protein
GS08_RS00175	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GS08_RS00200	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
GS08_RS00210	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GS08_RS00225	COG0180	Tryptophanyl-tRNA synthetase
GS08_RS00235	COG2197	response regulator
GS08_RS00255	COG0058	SHG alpha-glucan phosphorylase activity
GS08_RS00295	COG0515	serine threonine protein kinase
GS08_RS00300	COG0768	penicillin binding
GS08_RS00350	COG3853	Toxic anion resistance protein (TelA)
GS08_RS00355	COG0071	Belongs to the small heat shock protein (HSP20) family
GS08_RS00375	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
GS08_RS00400	COG0494	nUDIX hydrolase
GS08_RS00435	COG0343	queuine tRNA-ribosyltransferase activity
GS08_RS00480	COG0191	fructose-bisphosphate aldolase activity
GS08_RS00555	COG0477	Major facilitator Superfamily
GS08_RS00580	COG0366	Alpha amylase catalytic
GS08_RS00605	COG1175	transmembrane transport
GS08_RS00610	COG3833	ABC-type maltose transport systems, permease component
GS08_RS00615	COG1523	belongs to the glycosyl hydrolase 13 family
GS08_RS00630	COG1609	Transcriptional regulator
GS08_RS00670	COG0789	Transcriptional regulator
GS08_RS00675	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GS08_RS00680	COG1175	transmembrane transport
GS08_RS00685	COG0395	ABC-type sugar transport system, permease component
GS08_RS00700	COG1609	Transcriptional regulator
GS08_RS00705	COG0586	Pfam SNARE associated Golgi protein
GS08_RS00780	COG0527	aspartate kinase activity
GS08_RS00810	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GS08_RS00820	COG1754	DNA topoisomerase type I activity
GS08_RS00820	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GS08_RS00830	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GS08_RS00880	COG3152	Membrane
GS08_RS00895	COG3328	transposase activity
GS08_RS00900	COG0732	type I restriction modification DNA specificity domain
GS08_RS00935	COG3619	membrane
GS08_RS00945	COG0477	Major facilitator Superfamily
GS08_RS01060	COG0672	)-iron permease
GS08_RS01065	COG3470	protein probably involved in high-affinity Fe2 transport
GS08_RS01080	COG0577	efflux transmembrane transporter activity
GS08_RS01085	COG1136	(ABC) transporter
GS08_RS01115	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
GS08_RS01120	COG0363	glucosamine-6-phosphate deaminase activity
GS08_RS01145	COG1215	transferase activity, transferring glycosyl groups
GS08_RS01150	COG1309	transcriptional regulator
GS08_RS01175	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
GS08_RS01185	COG0305	Participates in initiation and elongation during chromosome replication
GS08_RS01190	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GS08_RS01195	COG3442	glutamine amidotransferase
GS08_RS01210	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
GS08_RS01215	COG3340	Belongs to the peptidase S51 family
GS08_RS01260	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
GS08_RS01265	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
GS08_RS01270	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GS08_RS01280	COG1937	Protein conserved in bacteria
GS08_RS01285	COG1322	Protein conserved in bacteria
GS08_RS01365	COG0745	RESPONSE REGULATOR receiver
GS08_RS01380	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GS08_RS01405	COG0356	it plays a direct role in the translocation of protons across the membrane
GS08_RS01440	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GS08_RS01450	COG0545	Peptidyl-prolyl cis-trans isomerase
GS08_RS01480	COG0251	oxidation-reduction process
GS08_RS01515	COG3842	ATPase activity
GS08_RS01530	COG1027	Aspartate ammonia-lyase
GS08_RS01545	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
GS08_RS01605	COG0789	Transcriptional regulator
GS08_RS01610	COG2270	Major facilitator Superfamily
GS08_RS01615	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
GS08_RS01615	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
GS08_RS01625	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GS08_RS01635	COG1175	transmembrane transport
GS08_RS01640	COG0395	ABC-type sugar transport system, permease component
GS08_RS01650	COG4948	Mandelate Racemase Muconate Lactonizing
GS08_RS01660	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GS08_RS01665	COG4154	Belongs to the RbsD FucU family
GS08_RS01680	COG0742	ribosomal rna small subunit methyltransferase
GS08_RS01690	COG0826	peptidase U32
GS08_RS01695	COG1496	oxidoreductase activity
GS08_RS01705	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GS08_RS01715	COG3579	cysteine-type endopeptidase activity
GS08_RS01720	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GS08_RS01725	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
GS08_RS01745	COG0477	Major facilitator Superfamily
GS08_RS01750	COG5002	protein histidine kinase activity
GS08_RS01755	COG0745	RESPONSE REGULATOR receiver
GS08_RS01780	COG1704	LemA family
GS08_RS01800	COG1957	nucleoside hydrolase
GS08_RS01825	COG1837	Belongs to the UPF0109 family
GS08_RS01855	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GS08_RS01855	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GS08_RS01885	COG0505	Belongs to the CarA family
GS08_RS01890	COG0488	(ABC) transporter
GS08_RS01900	COG0440	acetolactate synthase activity
GS08_RS01940	COG0667	Aldo Keto reductase
GS08_RS01975	COG2348	transferase activity, transferring amino-acyl groups
GS08_RS01980	COG2348	transferase activity, transferring amino-acyl groups
GS08_RS02010	COG1116	anion transmembrane transporter activity
GS08_RS02030	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GS08_RS02035	COG1609	Transcriptional regulator
GS08_RS02055	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GS08_RS02065	COG0577	efflux transmembrane transporter activity
GS08_RS02085	COG2814	Major facilitator Superfamily
GS08_RS02095	COG2814	Major facilitator Superfamily
GS08_RS02100	COG1653	transport
GS08_RS02105	COG1175	transmembrane transport
GS08_RS02110	COG0395	ABC-type sugar transport system, permease component
GS08_RS02125	COG3867	Arabinogalactan endo-beta-1,4-galactanase
GS08_RS02135	COG0656	L-ascorbic acid biosynthetic process
GS08_RS02175	COG4974	Belongs to the 'phage' integrase family
GS08_RS02180	COG2801	Transposase and inactivated derivatives
GS08_RS02200	COG0758	DNA mediated transformation
GS08_RS02215	COG0489	protein tyrosine kinase activity
GS08_RS02275	COG0095	Lipoate-protein ligase
GS08_RS02285	COG4499	WXG100 protein secretion system (Wss), protein YukC
GS08_RS02285	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GS08_RS02290	COG1902	pentaerythritol trinitrate reductase activity
GS08_RS02295	COG0167	dihydroorotate dehydrogenase activity
GS08_RS02300	COG1349	DNA-binding transcription factor activity
GS08_RS02310	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
GS08_RS02320	COG4209	transmembrane transport
GS08_RS02325	COG0395	ABC-type sugar transport system, permease component
GS08_RS02340	COG1621	beta-fructofuranosidase activity
GS08_RS02355	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
GS08_RS02425	COG1373	ATPase (AAA superfamily
GS08_RS02465	COG0714	Associated with various cellular activities
GS08_RS02505	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
GS08_RS02555	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GS08_RS02560	COG2884	Cell division ATP-binding protein ftsE
GS08_RS02565	COG2177	Part of the ABC transporter FtsEX involved in
GS08_RS02605	COG0564	pseudouridine synthase activity
GS08_RS02610	COG3550	peptidyl-serine autophosphorylation
GS08_RS02625	COG1175	transmembrane transport
GS08_RS02630	COG0395	ABC-type sugar transport system, permease component
GS08_RS02640	COG1609	Transcriptional regulator
GS08_RS02645	COG3534	alpha-L-arabinofuranosidase
GS08_RS02650	COG1653	transport
GS08_RS02655	COG1653	transport
GS08_RS02670	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
GS08_RS02675	COG0747	negative chemotaxis
GS08_RS02695	COG4608	Belongs to the ABC transporter superfamily
GS08_RS02705	COG0626	cystathionine gamma-synthase activity
GS08_RS02715	COG0514	ATP-dependent DNA helicase (RecQ)
GS08_RS02730	COG0531	amino acid
GS08_RS02735	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GS08_RS02745	COG0358	DNA primase activity
GS08_RS02760	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GS08_RS02770	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
GS08_RS02785	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GS08_RS02800	COG1136	(ABC) transporter
GS08_RS02800	COG0577	efflux transmembrane transporter activity
GS08_RS02810	COG0577	efflux transmembrane transporter activity
GS08_RS02810	COG1136	(ABC) transporter
GS08_RS02815	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GS08_RS02825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GS08_RS02830	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GS08_RS02855	COG1012	belongs to the aldehyde dehydrogenase family
GS08_RS02895	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GS08_RS02965	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
GS08_RS02995	COG0385	Bile acid
GS08_RS03025	COG0583	DNA-binding transcription factor activity
GS08_RS03050	COG1063	alcohol dehydrogenase
GS08_RS03080	COG1175	transmembrane transport
GS08_RS03120	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GS08_RS03135	COG0110	maltose O-acetyltransferase activity
GS08_RS03140	COG0110	maltose O-acetyltransferase activity
GS08_RS03150	COG3250	beta-galactosidase activity
GS08_RS03175	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GS08_RS03180	COG4721	ABC-type cobalt transport system, permease component
GS08_RS03185	COG1122	ATPase activity
GS08_RS03195	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GS08_RS03265	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
GS08_RS03270	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GS08_RS03310	COG0569	domain protein
GS08_RS03315	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
GS08_RS03325	COG0497	DNA recombination
GS08_RS03330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GS08_RS03370	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
GS08_RS03400	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GS08_RS03415	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GS08_RS03415	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GS08_RS03420	COG2116	formate transmembrane transporter activity
GS08_RS03445	COG0667	Aldo Keto reductase
GS08_RS03480	COG1760	l-serine dehydratase
GS08_RS03490	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GS08_RS03525	COG1674	ftsk spoiiie
GS08_RS03530	COG1316	TRANSCRIPTIONal
GS08_RS03575	COG2205	protein histidine kinase activity
GS08_RS03580	COG0745	RESPONSE REGULATOR receiver
GS08_RS03590	COG1329	Transcriptional regulator
GS08_RS03605	COG1121	(ABC) transporter
GS08_RS03610	COG0803	Belongs to the bacterial solute-binding protein 9 family
GS08_RS03620	COG0539	negative regulation of cytoplasmic translation
GS08_RS03640	COG0469	pyruvate kinase activity
GS08_RS03645	COG0494	nUDIX hydrolase
GS08_RS03665	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GS08_RS03670	COG1051	belongs to the nudix hydrolase family
GS08_RS03700	COG0519	Catalyzes the synthesis of GMP from XMP
GS08_RS03720	COG4974	Belongs to the 'phage' integrase family
GS08_RS03750	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
GS08_RS03760	COG1131	(ABC) transporter
GS08_RS03790	COG2801	Transposase and inactivated derivatives
GS08_RS03795	COG3250	beta-galactosidase activity
GS08_RS03830	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
GS08_RS03835	COG0280	phosphate acetyltransferase
GS08_RS03835	COG0857	belongs to the CobB CobQ family
GS08_RS03850	COG0406	alpha-ribazole phosphatase activity
GS08_RS03855	COG0799	negative regulation of ribosome biogenesis
GS08_RS03875	COG2755	lipolytic protein G-D-S-L family
GS08_RS03875	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
GS08_RS03895	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GS08_RS03900	COG1136	(ABC) transporter
GS08_RS03905	COG0577	efflux transmembrane transporter activity
GS08_RS03905	COG1136	(ABC) transporter
GS08_RS03925	COG2011	ABC-type metal ion transport system permease component
GS08_RS03930	COG1473	amidohydrolase
GS08_RS03945	COG1882	Formate acetyltransferase
GS08_RS03950	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
GS08_RS04010	COG1611	Belongs to the LOG family
GS08_RS04025	COG1053	succinate dehydrogenase
GS08_RS04030	COG0758	DNA mediated transformation
GS08_RS04050	COG2873	o-acetylhomoserine
GS08_RS04055	COG1136	(ABC) transporter
GS08_RS04060	COG0577	efflux transmembrane transporter activity
GS08_RS04060	COG1136	(ABC) transporter
GS08_RS04065	COG2197	response regulator
GS08_RS04080	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GS08_RS04085	COG0012	GTP binding
GS08_RS04090	COG3177	Filamentation induced by cAMP protein fic
GS08_RS04130	COG1309	transcriptional regulator
GS08_RS04140	COG2814	Major facilitator Superfamily
GS08_RS04150	COG2815	serine threonine protein kinase
GS08_RS04150	COG0515	serine threonine protein kinase
GS08_RS04195	COG2233	PERMEase
GS08_RS04200	COG0513	Belongs to the DEAD box helicase family
GS08_RS04210	COG0366	Alpha amylase catalytic
GS08_RS04215	COG0306	phosphate transporter
GS08_RS04225	COG2197	response regulator
GS08_RS04230	COG4585	Histidine kinase
GS08_RS04235	COG1131	(ABC) transporter
GS08_RS04280	COG3340	Belongs to the peptidase S51 family
GS08_RS04285	COG1335	isochorismatase
GS08_RS04310	COG3655	Transcriptional regulator
GS08_RS04340	COG1136	(ABC) transporter
GS08_RS04340	COG0577	efflux transmembrane transporter activity
GS08_RS04350	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
GS08_RS04380	COG2826	transposase and inactivated derivatives, IS30 family
GS08_RS04430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GS08_RS04445	COG0719	Fe-S assembly protein
GS08_RS04450	COG0396	ATPase activity
GS08_RS04455	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GS08_RS04465	COG2151	metal-sulfur cluster biosynthetic enzyme
GS08_RS04485	COG1385	rRNA (uridine-N3-)-methyltransferase activity
GS08_RS04490	COG0537	adenosine 5'-monophosphoramidase activity
GS08_RS04495	COG1702	phosphate starvation-inducible protein PhoH
GS08_RS04520	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
GS08_RS04545	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GS08_RS04550	COG2860	membrane
GS08_RS04555	COG3328	transposase activity
GS08_RS04580	COG1929	Belongs to the glycerate kinase type-1 family
GS08_RS04590	COG1609	Transcriptional regulator
GS08_RS04595	COG2814	Major facilitator Superfamily
GS08_RS04600	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GS08_RS04605	COG1609	Transcriptional regulator
GS08_RS04615	COG0069	glutamate synthase activity
GS08_RS04615	COG0070	glutamate synthase
GS08_RS04615	COG0067	glutamate synthase
GS08_RS04625	COG4166	transmembrane transport
GS08_RS04640	COG0297	glycogen (starch) synthase activity
GS08_RS04645	COG1119	ATPase activity
GS08_RS04710	COG3328	transposase activity
GS08_RS04735	COG0513	Belongs to the DEAD box helicase family
GS08_RS04755	COG2962	Rard protein
GS08_RS04765	COG1073	alpha beta
GS08_RS04775	COG0588	phosphoglycerate mutase activity
GS08_RS04785	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
GS08_RS04810	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GS08_RS04815	COG0284	orotidine-5'-phosphate decarboxylase activity
GS08_RS04820	COG0543	2 iron, 2 sulfur cluster binding
GS08_RS04825	COG0167	dihydroorotate dehydrogenase activity
GS08_RS04845	COG0583	DNA-binding transcription factor activity
GS08_RS04870	COG3189	MarR family transcriptional regulator
GS08_RS04915	COG0681	Belongs to the peptidase S26 family
GS08_RS04925	COG0833	amino acid
GS08_RS04940	COG0706	membrane insertase activity
GS08_RS04945	COG0706	membrane insertase activity
GS08_RS04950	COG1051	belongs to the nudix hydrolase family
GS08_RS04985	COG1131	(ABC) transporter
GS08_RS05030	COG4181	ATPase activity
GS08_RS05045	COG0745	RESPONSE REGULATOR receiver
GS08_RS05110	COG0833	amino acid
GS08_RS05120	COG2135	peptidase activity
GS08_RS05125	COG0133	tryptophan synthase activity
GS08_RS05140	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GS08_RS05155	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
GS08_RS05175	COG1716	ATPase activity
GS08_RS05235	COG1187	pseudouridine synthase activity
GS08_RS05240	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
GS08_RS05260	COG0045	succinate-CoA ligase (ADP-forming) activity
GS08_RS05360	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GS08_RS05380	COG0436	Aminotransferase
GS08_RS05395	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GS08_RS05420	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GS08_RS05455	COG1136	(ABC) transporter
GS08_RS05455	COG0577	efflux transmembrane transporter activity
GS08_RS05460	COG1136	(ABC) transporter
GS08_RS05460	COG0577	efflux transmembrane transporter activity
GS08_RS05475	COG0745	RESPONSE REGULATOR receiver
GS08_RS05510	COG4221	oxidoreductase activity
GS08_RS05515	COG0488	(ABC) transporter
GS08_RS05530	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
GS08_RS05550	COG0693	protein deglycase activity
GS08_RS05560	COG0575	Belongs to the CDS family
GS08_RS05600	COG0516	GMP reductase activity
GS08_RS05630	COG2197	response regulator
GS08_RS05635	COG4585	Histidine kinase
GS08_RS05705	COG0456	acetyltransferase
GS08_RS05715	COG0802	atpase or kinase
GS08_RS05730	COG1555	photosystem II stabilization
GS08_RS05730	COG1596	polysaccharide export
GS08_RS05740	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GS08_RS05745	COG0598	Magnesium transport protein CorA
GS08_RS05750	COG0406	alpha-ribazole phosphatase activity
GS08_RS05830	COG2801	Transposase and inactivated derivatives
GS08_RS05870	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GS08_RS05895	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GS08_RS05905	COG1201	RNA secondary structure unwinding
GS08_RS05910	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GS08_RS05920	COG0187	DNA topoisomerase II activity
GS08_RS05925	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GS08_RS05935	COG0142	geranyltranstransferase activity
GS08_RS05955	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GS08_RS05980	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GS08_RS06000	COG1396	sequence-specific DNA binding
GS08_RS06035	COG2357	RelA SpoT domain protein
GS08_RS06045	COG0670	Belongs to the BI1 family
GS08_RS06100	COG0708	Exodeoxyribonuclease III
GS08_RS06110	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GS08_RS06115	COG0601	transmembrane transport
GS08_RS06120	COG4166	transmembrane transport
GS08_RS06135	COG0287	Prephenate dehydrogenase
GS08_RS06140	COG1605	Chorismate mutase
GS08_RS06140	COG0077	Prephenate dehydratase
GS08_RS06150	COG1217	gtp-binding protein TYPA
GS08_RS06160	COG1136	(ABC) transporter
GS08_RS06160	COG4591	ABC-type transport system involved in lipoprotein release permease component
GS08_RS06170	COG0477	Major facilitator Superfamily
GS08_RS06175	COG1104	cysteine desulfurase activity
GS08_RS06185	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GS08_RS06190	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GS08_RS06200	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
GS08_RS06205	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
GS08_RS06230	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GS08_RS06245	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
GS08_RS06290	COG2801	Transposase and inactivated derivatives
GS08_RS06300	COG2826	transposase and inactivated derivatives, IS30 family
GS08_RS06345	COG2017	converts alpha-aldose to the beta-anomer
GS08_RS06350	COG2017	converts alpha-aldose to the beta-anomer
GS08_RS06360	COG1595	DNA-templated transcription, initiation
GS08_RS06375	COG1196	nuclear chromosome segregation
GS08_RS06380	COG0285	dihydrofolate synthase activity
GS08_RS06390	COG0006	proline dipeptidase activity
GS08_RS06400	COG4172	Belongs to the ABC transporter superfamily
GS08_RS06410	COG0601	transmembrane transport
GS08_RS06415	COG4166	transmembrane transport
GS08_RS06435	COG1940	carbohydrate kinase activity
GS08_RS06470	COG1472	Belongs to the glycosyl hydrolase 3 family
GS08_RS06480	COG0395	ABC-type sugar transport system, permease component
GS08_RS06485	COG1175	transmembrane transport
GS08_RS06520	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GS08_RS06565	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GS08_RS06575	COG0768	penicillin binding
GS08_RS06600	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GS08_RS06630	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GS08_RS06635	COG2813	Specifically methylates the guanine in position
GS08_RS06640	COG1643	Atp-dependent helicase
GS08_RS06660	COG0395	ABC-type sugar transport system, permease component
GS08_RS06665	COG1175	transmembrane transport
GS08_RS06675	COG1609	Transcriptional regulator
GS08_RS06680	COG2814	Major facilitator Superfamily
GS08_RS06685	COG0174	glutamine synthetase
GS08_RS06730	COG0656	L-ascorbic acid biosynthetic process
GS08_RS06755	COG4716	Myosin-crossreactive antigen
GS08_RS06765	COG0587	DNA-directed DNA polymerase activity
GS08_RS06800	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GS08_RS06825	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GS08_RS06830	COG0352	thiamine-phosphate diphosphorylase activity
GS08_RS06830	COG0351	phosphomethylpyrimidine kinase
GS08_RS06840	COG2271	Major facilitator Superfamily
GS08_RS06850	COG2197	response regulator
GS08_RS06885	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
GS08_RS06895	COG1957	nucleoside hydrolase
GS08_RS06940	COG3480	Lon protease (S16) C-terminal proteolytic domain
GS08_RS06975	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GS08_RS06995	COG0765	amino acid transport
GS08_RS07000	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GS08_RS07005	COG1126	abc transporter atp-binding protein
GS08_RS07015	COG1473	amidohydrolase
GS08_RS07030	COG0559	Belongs to the binding-protein-dependent transport system permease family
GS08_RS07045	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GS08_RS07060	COG0626	cystathionine gamma-synthase activity
GS08_RS07070	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GS08_RS07075	COG2176	DNA-directed DNA polymerase activity
GS08_RS07085	COG0284	orotidine-5'-phosphate decarboxylase activity
GS08_RS07110	COG1136	(ABC) transporter
GS08_RS07110	COG0577	efflux transmembrane transporter activity
GS08_RS07115	COG0390	transport system, permease component
GS08_RS07120	COG1376	ErfK ybiS ycfS ynhG family protein
GS08_RS07135	COG1250	3-hydroxyacyl-CoA dehydrogenase
GS08_RS07150	COG0395	ABC-type sugar transport system, permease component
GS08_RS07155	COG1175	transmembrane transport
GS08_RS07195	COG1122	ATPase activity
GS08_RS07240	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GS08_RS07245	COG2814	Major facilitator Superfamily
GS08_RS07280	COG0745	RESPONSE REGULATOR receiver
GS08_RS07290	COG4581	dead DEAH box helicase
GS08_RS07295	COG2326	polyphosphate kinase activity
GS08_RS07315	COG0765	amino acid transport
GS08_RS07320	COG0765	amino acid transport
GS08_RS07325	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
GS08_RS07330	COG1126	abc transporter atp-binding protein
GS08_RS07350	COG1196	nuclear chromosome segregation
GS08_RS07365	COG0477	Major facilitator Superfamily
GS08_RS07375	COG0402	S-adenosylhomocysteine deaminase activity
GS08_RS07385	COG0589	response to stress
GS08_RS07425	COG1278	Cold shock
GS08_RS07430	COG2205	protein histidine kinase activity
GS08_RS07435	COG0745	RESPONSE REGULATOR receiver
GS08_RS07455	COG1278	Cold shock
GS08_RS07470	COG0714	Associated with various cellular activities
GS08_RS07520	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
GS08_RS07560	COG0586	Pfam SNARE associated Golgi protein
GS08_RS07565	COG0560	Phosphoserine phosphatase
GS08_RS07570	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GS08_RS07600	COG3328	transposase activity
GS08_RS07610	COG3328	transposase activity
GS08_RS07615	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GS08_RS07660	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
GS08_RS07665	COG3250	beta-galactosidase activity
GS08_RS07670	COG1609	Transcriptional regulator
GS08_RS07680	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
GS08_RS07685	COG1869	D-ribose catabolic process
GS08_RS07695	COG1172	Belongs to the binding-protein-dependent transport system permease family
GS08_RS07700	COG1129	ABC transporter
GS08_RS07710	COG1132	(ABC) transporter
GS08_RS07715	COG1132	(ABC) transporter
GS08_RS07720	COG4251	negative regulation of phosphorylation
GS08_RS07720	COG5001	Diguanylate cyclase
GS08_RS07720	COG2203	Gaf domain
GS08_RS07720	COG3706	GGDEF domain
GS08_RS07765	COG1472	Belongs to the glycosyl hydrolase 3 family
GS08_RS07800	COG1309	transcriptional regulator
GS08_RS07815	COG0602	queuosine metabolic process
GS08_RS07820	COG1328	CTP reductase activity
GS08_RS07820	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GS08_RS07825	COG1570	exodeoxyribonuclease VII activity
GS08_RS07830	COG1722	exodeoxyribonuclease VII activity
GS08_RS07840	COG2249	NAD(P)H dehydrogenase (quinone) activity
GS08_RS07850	COG1970	mechanosensitive ion channel activity
GS08_RS07875	COG0248	Ppx GppA phosphatase
GS08_RS07880	COG0436	Aminotransferase
GS08_RS07965	COG1355	regulation of microtubule-based process
GS08_RS07970	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GS08_RS07985	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GS08_RS07990	COG0009	L-threonylcarbamoyladenylate synthase
GS08_RS08025	COG1070	Carbohydrate kinase
GS08_RS08040	COG3328	transposase activity
GS08_RS08045	COG4214	carbohydrate transport
GS08_RS08055	COG4213	ABC transporter substrate-binding protein
GS08_RS08070	COG0110	maltose O-acetyltransferase activity
GS08_RS08075	COG3507	Belongs to the glycosyl hydrolase 43 family
GS08_RS08100	COG3507	Belongs to the glycosyl hydrolase 43 family
GS08_RS08105	COG0395	ABC-type sugar transport system, permease component
GS08_RS08110	COG1175	transmembrane transport
GS08_RS08120	COG1609	Transcriptional regulator
GS08_RS08125	COG1979	alcohol dehydrogenase
GS08_RS08135	COG2814	Major facilitator Superfamily
GS08_RS08140	COG2814	Major facilitator Superfamily
GS08_RS08150	COG0242	peptide deformylase activity
GS08_RS08160	COG2814	Major facilitator Superfamily
GS08_RS08175	COG4214	carbohydrate transport
GS08_RS08195	COG1129	ABC transporter
GS08_RS08200	COG1940	carbohydrate kinase activity
GS08_RS08220	COG1946	Acyl-CoA thioesterase
GS08_RS08230	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GS08_RS08235	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GS08_RS08245	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GS08_RS08250	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
GS08_RS08290	COG1454	alcohol dehydrogenase
GS08_RS08295	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
GS08_RS08310	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GS08_RS08345	COG0488	(ABC) transporter
GS08_RS08370	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
GS08_RS08375	COG1687	branched-chain amino acid
GS08_RS08380	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GS08_RS08400	COG0589	response to stress
GS08_RS08405	COG0791	NLP P60 protein
GS08_RS08415	COG1705	Flagellar rod assembly protein muramidase FlgJ
GS08_RS08415	COG3942	CHAP domain
GS08_RS08420	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GS08_RS08430	COG5002	protein histidine kinase activity
GS08_RS08435	COG0704	Plays a role in the regulation of phosphate uptake
GS08_RS08445	COG1575	Belongs to the MenA family. Type 1 subfamily
GS08_RS08450	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GS08_RS08460	COG2814	Major facilitator Superfamily
GS08_RS08520	COG0395	ABC-type sugar transport system, permease component
GS08_RS08525	COG1175	transmembrane transport
GS08_RS08580	COG1597	lipid kinase activity
GS08_RS08580	COG1803	Methylglyoxal synthase
GS08_RS08585	COG3711	transcriptional antiterminator
GS08_RS08615	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GS08_RS08620	COG0328	RNA-DNA hybrid ribonuclease activity
GS08_RS08640	COG0196	riboflavin kinase activity
GS08_RS08675	COG3534	alpha-L-arabinofuranosidase
GS08_RS08690	COG2308	Evidence 4 Homologs of previously reported genes of
GS08_RS08795	COG0255	Belongs to the universal ribosomal protein uL29 family
GS08_RS08845	COG3527	Alpha-acetolactate decarboxylase
GS08_RS08855	COG1454	alcohol dehydrogenase
GS08_RS08855	COG1012	belongs to the aldehyde dehydrogenase family
GS08_RS08890	COG1739	Uncharacterized protein family UPF0029
GS08_RS08895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GS08_RS08915	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GS08_RS08930	COG0531	amino acid
GS08_RS08935	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GS08_RS09025	COG2252	PERMEase
GS08_RS09040	COG1132	(ABC) transporter
GS08_RS09045	COG1122	ATPase activity
GS08_RS09120	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GS08_RS09125	COG4770	biotin carboxylase activity
GS08_RS09130	COG1268	BioY protein
GS08_RS09185	COG0250	Participates in transcription elongation, termination and antitermination
GS08_RS09190	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
GS08_RS09200	COG0436	Aminotransferase
GS08_RS09225	COG1530	ribonuclease E activity
GS08_RS09230	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
GS08_RS09240	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GS08_RS09260	COG4948	Mandelate Racemase Muconate Lactonizing
GS08_RS09265	COG1609	Transcriptional regulator
GS08_RS09275	COG1136	(ABC) transporter
GS08_RS09290	COG0083	homoserine kinase activity
GS08_RS09295	COG0460	homoserine dehydrogenase
GS08_RS09320	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GS08_RS09325	COG0446	pyridine nucleotide-disulphide oxidoreductase
GS08_RS09330	COG0167	dihydroorotate dehydrogenase activity
GS08_RS09355	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GS08_RS09360	COG0494	nUDIX hydrolase
GS08_RS09360	COG0406	alpha-ribazole phosphatase activity
GS08_RS09385	COG0584	glycerophosphoryl diester phosphodiesterase
GS08_RS09400	COG2986	histidine ammonia-lyase
GS08_RS09410	COG0179	Fumarylacetoacetate (FAA) hydrolase
GS08_RS09425	COG3328	transposase activity
GS08_RS09435	COG1088	dTDP-glucose 4,6-dehydratase activity
GS08_RS09440	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GS08_RS09455	COG1484	DNA-dependent DNA replication
GS08_RS09520	COG1442	glycosyl transferase family 8
GS08_RS09530	COG1088	dTDP-glucose 4,6-dehydratase activity
GS08_RS09550	COG1129	ABC transporter
GS08_RS09575	COG0084	hydrolase, TatD family'
GS08_RS09590	COG4974	Belongs to the 'phage' integrase family
GS08_RS09615	COG0084	hydrolase, TatD family'
GS08_RS09675	COG0395	ABC-type sugar transport system, permease component
GS08_RS09680	COG4209	transmembrane transport
GS08_RS09700	COG1132	(ABC) transporter
GS08_RS09705	COG1132	(ABC) transporter
GS08_RS09725	COG0395	ABC-type sugar transport system, permease component
GS08_RS09730	COG1175	transmembrane transport
GS08_RS09740	COG1609	Transcriptional regulator
GS08_RS09745	COG1874	Beta-galactosidase
GS08_RS09760	COG4166	transmembrane transport
GS08_RS09835	COG1132	(ABC) transporter
GS08_RS09845	COG1846	Transcriptional regulator
GS08_RS09850	COG3645	SOS response
GS08_RS09870	COG1113	amino acid transport
GS08_RS09910	COG1175	transmembrane transport
GS08_RS09945	COG1113	amino acid transport
GS08_RS09975	COG1609	Transcriptional regulator
GS08_RS09985	COG0588	phosphoglycerate mutase activity
GS08_RS09995	COG0778	Nitroreductase
GS08_RS10005	COG1511	domain protein
GS08_RS10030	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GS08_RS10035	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GS08_RS10040	COG0366	Alpha amylase catalytic
GS08_RS10050	COG0366	Alpha amylase catalytic
GS08_RS10055	COG0395	ABC-type sugar transport system, permease component
GS08_RS10075	COG1609	Transcriptional regulator
GS08_RS10080	COG1609	Transcriptional regulator
GS08_RS10085	COG0395	ABC-type sugar transport system, permease component
GS08_RS10090	COG1175	transmembrane transport
GS08_RS10110	COG0590	tRNA wobble adenosine to inosine editing
GS08_RS10110	COG0037	tRNA processing
GS08_RS10115	COG0025	NhaP-type Na H and K H
GS08_RS10140	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
GS08_RS10160	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GS08_RS10170	COG3842	ATPase activity
GS08_RS10175	COG1216	Glycosyl transferase, family 2
GS08_RS10185	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GS08_RS10215	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GS08_RS10240	COG3583	domain protein
GS08_RS10260	COG0617	tRNA 3'-terminal CCA addition
GS08_RS10285	COG1475	DNA binding
GS08_RS10290	COG1192	Involved in chromosome partitioning
GS08_RS10355	COG2205	protein histidine kinase activity
GS08_RS10375	COG4106	trans-aconitate 2-methyltransferase activity
GS08_RS10390	COG1442	glycosyl transferase family 8