locus-tag	class	description
BN1726_RS00030	COG0438	transferase activity, transferring glycosyl groups
BN1726_RS00090	COG4974	Belongs to the 'phage' integrase family
BN1726_RS00115	COG2801	Transposase and inactivated derivatives
BN1726_RS00155	COG0489	protein tyrosine kinase activity
BN1726_RS00170	COG3118	belongs to the thioredoxin family
BN1726_RS00170	COG0492	ferredoxin-NADP+ reductase activity
BN1726_RS00215	COG0095	Lipoate-protein ligase
BN1726_RS00225	COG4499	WXG100 protein secretion system (Wss), protein YukC
BN1726_RS00225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BN1726_RS00230	COG1902	pentaerythritol trinitrate reductase activity
BN1726_RS00235	COG0167	dihydroorotate dehydrogenase activity
BN1726_RS00245	COG1349	DNA-binding transcription factor activity
BN1726_RS00255	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BN1726_RS00270	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BN1726_RS00275	COG1194	a g-specific adenine glycosylase
BN1726_RS00320	COG0714	Associated with various cellular activities
BN1726_RS00360	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BN1726_RS00405	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BN1726_RS00410	COG2884	Cell division ATP-binding protein ftsE
BN1726_RS00415	COG2177	Part of the ABC transporter FtsEX involved in
BN1726_RS00420	COG1388	LysM domain
BN1726_RS00420	COG3942	CHAP domain
BN1726_RS00455	COG0564	pseudouridine synthase activity
BN1726_RS00460	COG3550	peptidyl-serine autophosphorylation
BN1726_RS00480	COG1175	transmembrane transport
BN1726_RS00485	COG0395	ABC-type sugar transport system, permease component
BN1726_RS00500	COG3534	alpha-L-arabinofuranosidase
BN1726_RS00505	COG1653	transport
BN1726_RS00510	COG1653	transport
BN1726_RS00525	COG0747	negative chemotaxis
BN1726_RS00530	COG0601	transmembrane transport
BN1726_RS00535	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BN1726_RS00555	COG0626	cystathionine gamma-synthase activity
BN1726_RS00565	COG0514	ATP-dependent DNA helicase (RecQ)
BN1726_RS00580	COG0531	amino acid
BN1726_RS00585	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BN1726_RS00595	COG0358	DNA primase activity
BN1726_RS00605	COG3655	Transcriptional regulator
BN1726_RS00620	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BN1726_RS00630	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BN1726_RS00645	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BN1726_RS00660	COG0577	efflux transmembrane transporter activity
BN1726_RS00660	COG1136	(ABC) transporter
BN1726_RS00670	COG0577	efflux transmembrane transporter activity
BN1726_RS00670	COG1136	(ABC) transporter
BN1726_RS00675	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BN1726_RS00685	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BN1726_RS00690	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BN1726_RS00715	COG1012	belongs to the aldehyde dehydrogenase family
BN1726_RS00745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN1726_RS00755	COG0402	S-adenosylhomocysteine deaminase activity
BN1726_RS00760	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BN1726_RS00765	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BN1726_RS00775	COG0667	Aldo Keto reductase
BN1726_RS00805	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BN1726_RS00835	COG0385	Bile acid
BN1726_RS00870	COG0583	DNA-binding transcription factor activity
BN1726_RS00895	COG1063	alcohol dehydrogenase
BN1726_RS00940	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BN1726_RS00960	COG0110	maltose O-acetyltransferase activity
BN1726_RS00965	COG0110	maltose O-acetyltransferase activity
BN1726_RS00975	COG3250	beta-galactosidase activity
BN1726_RS01000	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BN1726_RS01005	COG4721	ABC-type cobalt transport system, permease component
BN1726_RS01010	COG1122	ATPase activity
BN1726_RS01020	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN1726_RS01095	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BN1726_RS01100	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BN1726_RS01140	COG0569	domain protein
BN1726_RS01145	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BN1726_RS01155	COG0497	DNA recombination
BN1726_RS01160	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BN1726_RS01185	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN1726_RS01215	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BN1726_RS01230	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BN1726_RS01230	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BN1726_RS01245	COG0667	Aldo Keto reductase
BN1726_RS01475	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BN1726_RS01480	COG3657	addiction module killer protein
BN1726_RS01580	COG3723	Recombinational DNA repair protein, rece pathway
BN1726_RS01640	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BN1726_RS01645	COG1760	l-serine dehydratase
BN1726_RS01655	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BN1726_RS01685	COG1316	TRANSCRIPTIONal
BN1726_RS01715	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BN1726_RS01725	COG2205	protein histidine kinase activity
BN1726_RS01730	COG0745	RESPONSE REGULATOR receiver
BN1726_RS01740	COG1329	Transcriptional regulator
BN1726_RS01755	COG1121	(ABC) transporter
BN1726_RS01770	COG0539	negative regulation of cytoplasmic translation
BN1726_RS01790	COG0469	pyruvate kinase activity
BN1726_RS01795	COG0494	nUDIX hydrolase
BN1726_RS01815	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BN1726_RS01820	COG1051	belongs to the nudix hydrolase family
BN1726_RS01850	COG0519	Catalyzes the synthesis of GMP from XMP
BN1726_RS01860	COG3250	beta-galactosidase activity
BN1726_RS01895	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BN1726_RS01900	COG0280	phosphate acetyltransferase
BN1726_RS01900	COG0857	belongs to the CobB CobQ family
BN1726_RS01915	COG0406	alpha-ribazole phosphatase activity
BN1726_RS01920	COG0799	negative regulation of ribosome biogenesis
BN1726_RS01940	COG2755	lipolytic protein G-D-S-L family
BN1726_RS01940	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BN1726_RS02025	COG2011	ABC-type metal ion transport system permease component
BN1726_RS02030	COG1473	amidohydrolase
BN1726_RS02050	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BN1726_RS02110	COG1611	Belongs to the LOG family
BN1726_RS02125	COG1053	succinate dehydrogenase
BN1726_RS02130	COG0758	DNA mediated transformation
BN1726_RS02150	COG2873	o-acetylhomoserine
BN1726_RS02155	COG1136	(ABC) transporter
BN1726_RS02160	COG0577	efflux transmembrane transporter activity
BN1726_RS02160	COG1136	(ABC) transporter
BN1726_RS02165	COG2197	response regulator
BN1726_RS02170	COG4585	Histidine kinase
BN1726_RS02180	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BN1726_RS02185	COG0012	GTP binding
BN1726_RS02220	COG2814	Major facilitator Superfamily
BN1726_RS02235	COG2815	serine threonine protein kinase
BN1726_RS02235	COG0515	serine threonine protein kinase
BN1726_RS02275	COG2233	PERMEase
BN1726_RS02280	COG0513	Belongs to the DEAD box helicase family
BN1726_RS02285	COG1309	transcriptional regulator
BN1726_RS02295	COG1966	Carbon starvation protein
BN1726_RS02305	COG0306	phosphate transporter
BN1726_RS02315	COG2197	response regulator
BN1726_RS02320	COG4585	Histidine kinase
BN1726_RS02325	COG1131	(ABC) transporter
BN1726_RS02375	COG3655	Transcriptional regulator
BN1726_RS02405	COG0577	efflux transmembrane transporter activity
BN1726_RS02405	COG1136	(ABC) transporter
BN1726_RS02415	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BN1726_RS02415	COG2755	lipolytic protein G-D-S-L family
BN1726_RS02420	COG0588	phosphoglycerate mutase activity
BN1726_RS02465	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BN1726_RS02495	COG0719	Fe-S assembly protein
BN1726_RS02500	COG0396	ATPase activity
BN1726_RS02505	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BN1726_RS02515	COG2151	metal-sulfur cluster biosynthetic enzyme
BN1726_RS02535	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BN1726_RS02540	COG0537	adenosine 5'-monophosphoramidase activity
BN1726_RS02545	COG1702	phosphate starvation-inducible protein PhoH
BN1726_RS02565	COG1022	Amp-dependent synthetase and ligase
BN1726_RS02570	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BN1726_RS02600	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BN1726_RS02610	COG2860	membrane
BN1726_RS02635	COG1929	Belongs to the glycerate kinase type-1 family
BN1726_RS02640	COG2826	transposase and inactivated derivatives, IS30 family
BN1726_RS02660	COG1609	Transcriptional regulator
BN1726_RS02710	COG0067	glutamate synthase
BN1726_RS02710	COG0069	glutamate synthase activity
BN1726_RS02710	COG0070	glutamate synthase
BN1726_RS02730	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BN1726_RS02740	COG4166	transmembrane transport
BN1726_RS02755	COG0297	glycogen (starch) synthase activity
BN1726_RS02760	COG1119	ATPase activity
BN1726_RS02765	COG0561	phosphatase activity
BN1726_RS02765	COG0561	phosphatase activity
BN1726_RS02770	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BN1726_RS02795	COG1397	ADP-ribosylglycohydrolase
BN1726_RS02860	COG4974	Belongs to the 'phage' integrase family
BN1726_RS02885	COG4989	oxidoreductase activity
BN1726_RS02910	COG0588	phosphoglycerate mutase activity
BN1726_RS02920	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BN1726_RS02945	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BN1726_RS02950	COG0284	orotidine-5'-phosphate decarboxylase activity
BN1726_RS02955	COG0543	2 iron, 2 sulfur cluster binding
BN1726_RS02960	COG0167	dihydroorotate dehydrogenase activity
BN1726_RS02975	COG0583	DNA-binding transcription factor activity
BN1726_RS03010	COG0681	Belongs to the peptidase S26 family
BN1726_RS03015	COG0833	amino acid
BN1726_RS03030	COG0706	membrane insertase activity
BN1726_RS03065	COG0577	efflux transmembrane transporter activity
BN1726_RS03065	COG1136	(ABC) transporter
BN1726_RS03075	COG4585	Histidine kinase
BN1726_RS03080	COG2197	response regulator
BN1726_RS03090	COG1131	(ABC) transporter
BN1726_RS03120	COG1131	(ABC) transporter
BN1726_RS03195	COG0133	tryptophan synthase activity
BN1726_RS03210	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BN1726_RS03225	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BN1726_RS03245	COG1716	ATPase activity
BN1726_RS03260	COG1803	Methylglyoxal synthase
BN1726_RS03345	COG0513	Belongs to the DEAD box helicase family
BN1726_RS03420	COG1187	pseudouridine synthase activity
BN1726_RS03425	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BN1726_RS03450	COG0045	succinate-CoA ligase (ADP-forming) activity
BN1726_RS03535	COG4974	Belongs to the 'phage' integrase family
BN1726_RS03580	COG3617	BRO family, N-terminal domain
BN1726_RS03840	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BN1726_RS03855	COG0436	Aminotransferase
BN1726_RS03870	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BN1726_RS03895	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BN1726_RS03945	COG1129	ABC transporter
BN1726_RS03960	COG1028	Short-chain dehydrogenase reductase Sdr
BN1726_RS03965	COG0488	(ABC) transporter
BN1726_RS03990	COG0693	protein deglycase activity
BN1726_RS04000	COG0575	Belongs to the CDS family
BN1726_RS04040	COG0516	GMP reductase activity
BN1726_RS04100	COG1192	Involved in chromosome partitioning
BN1726_RS04235	COG0551	DNA topoisomerase type I activity
BN1726_RS04235	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BN1726_RS04255	COG3942	CHAP domain
BN1726_RS04320	COG0456	acetyltransferase
BN1726_RS04335	COG1228	amidohydrolase
BN1726_RS04345	COG1596	polysaccharide export
BN1726_RS04345	COG1555	photosystem II stabilization
BN1726_RS04360	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN1726_RS04365	COG0598	Magnesium transport protein CorA
BN1726_RS04370	COG0406	alpha-ribazole phosphatase activity
BN1726_RS04405	COG2801	Transposase and inactivated derivatives
BN1726_RS04410	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BN1726_RS04435	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BN1726_RS04445	COG1201	RNA secondary structure unwinding
BN1726_RS04450	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BN1726_RS04460	COG0187	DNA topoisomerase II activity
BN1726_RS04465	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BN1726_RS04475	COG0142	geranyltranstransferase activity
BN1726_RS04495	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BN1726_RS04510	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BN1726_RS04535	COG1396	sequence-specific DNA binding
BN1726_RS04540	COG1546	Belongs to the CinA family
BN1726_RS04540	COG1058	Belongs to the CinA family
BN1726_RS04570	COG2357	RelA SpoT domain protein
BN1726_RS04580	COG0670	Belongs to the BI1 family
BN1726_RS04595	COG2197	response regulator
BN1726_RS04650	COG0708	Exodeoxyribonuclease III
BN1726_RS04660	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BN1726_RS04665	COG0601	transmembrane transport
BN1726_RS04670	COG4166	transmembrane transport
BN1726_RS04685	COG0287	Prephenate dehydrogenase
BN1726_RS04690	COG1605	Chorismate mutase
BN1726_RS04690	COG0077	Prephenate dehydratase
BN1726_RS04700	COG1217	gtp-binding protein TYPA
BN1726_RS04705	COG0477	Major facilitator Superfamily
BN1726_RS04710	COG1104	cysteine desulfurase activity
BN1726_RS04720	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BN1726_RS04725	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BN1726_RS04735	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BN1726_RS04740	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BN1726_RS04750	COG1136	(ABC) transporter
BN1726_RS04750	COG0577	efflux transmembrane transporter activity
BN1726_RS04770	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BN1726_RS04790	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BN1726_RS04800	COG2017	converts alpha-aldose to the beta-anomer
BN1726_RS04805	COG2017	converts alpha-aldose to the beta-anomer
BN1726_RS04815	COG1595	DNA-templated transcription, initiation
BN1726_RS04830	COG1196	nuclear chromosome segregation
BN1726_RS04835	COG0285	dihydrofolate synthase activity
BN1726_RS04850	COG0006	proline dipeptidase activity
BN1726_RS04870	COG0601	transmembrane transport
BN1726_RS04875	COG4166	transmembrane transport
BN1726_RS04895	COG1940	carbohydrate kinase activity
BN1726_RS04955	COG1472	Belongs to the glycosyl hydrolase 3 family
BN1726_RS04965	COG0395	ABC-type sugar transport system, permease component
BN1726_RS04970	COG1175	transmembrane transport
BN1726_RS05000	COG3657	addiction module killer protein
BN1726_RS05005	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BN1726_RS05055	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BN1726_RS05065	COG0768	penicillin binding
BN1726_RS05090	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BN1726_RS05120	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BN1726_RS05130	COG2813	Specifically methylates the guanine in position
BN1726_RS05135	COG1643	Atp-dependent helicase
BN1726_RS05150	COG0174	glutamine synthetase
BN1726_RS05200	COG0656	L-ascorbic acid biosynthetic process
BN1726_RS05230	COG4716	Myosin-crossreactive antigen
BN1726_RS05240	COG0587	DNA-directed DNA polymerase activity
BN1726_RS05255	COG1373	ATPase (AAA superfamily
BN1726_RS05290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BN1726_RS05325	COG0351	phosphomethylpyrimidine kinase
BN1726_RS05325	COG0352	thiamine-phosphate diphosphorylase activity
BN1726_RS05335	COG2271	Major facilitator Superfamily
BN1726_RS05375	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BN1726_RS05385	COG1957	nucleoside hydrolase
BN1726_RS05430	COG3480	Lon protease (S16) C-terminal proteolytic domain
BN1726_RS05465	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BN1726_RS05490	COG2873	o-acetylhomoserine
BN1726_RS05505	COG1959	2 iron, 2 sulfur cluster binding
BN1726_RS05515	COG0626	cystathionine gamma-synthase activity
BN1726_RS05520	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN1726_RS05525	COG1126	abc transporter atp-binding protein
BN1726_RS05530	COG0765	amino acid transport
BN1726_RS05545	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BN1726_RS05560	COG0284	orotidine-5'-phosphate decarboxylase activity
BN1726_RS05585	COG1136	(ABC) transporter
BN1726_RS05585	COG0577	efflux transmembrane transporter activity
BN1726_RS05590	COG0390	transport system, permease component
BN1726_RS05595	COG1376	ErfK ybiS ycfS ynhG family protein
BN1726_RS05605	COG4106	trans-aconitate 2-methyltransferase activity
BN1726_RS05620	COG1250	3-hydroxyacyl-CoA dehydrogenase
BN1726_RS05625	COG1501	Belongs to the glycosyl hydrolase 31 family
BN1726_RS05640	COG0395	ABC-type sugar transport system, permease component
BN1726_RS05690	COG1122	ATPase activity
BN1726_RS05810	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BN1726_RS05815	COG2814	Major facilitator Superfamily
BN1726_RS05850	COG0745	RESPONSE REGULATOR receiver
BN1726_RS05860	COG4581	dead DEAH box helicase
BN1726_RS05865	COG2326	polyphosphate kinase activity
BN1726_RS05885	COG0765	amino acid transport
BN1726_RS05890	COG0765	amino acid transport
BN1726_RS05895	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BN1726_RS05900	COG1126	abc transporter atp-binding protein
BN1726_RS05925	COG1196	nuclear chromosome segregation
BN1726_RS05940	COG0477	Major facilitator Superfamily
BN1726_RS05950	COG0402	S-adenosylhomocysteine deaminase activity
BN1726_RS05960	COG0589	response to stress
BN1726_RS05970	COG1278	Cold shock
BN1726_RS05975	COG2205	protein histidine kinase activity
BN1726_RS05980	COG0745	RESPONSE REGULATOR receiver
BN1726_RS06000	COG1278	Cold shock
BN1726_RS06015	COG0714	Associated with various cellular activities
BN1726_RS06070	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BN1726_RS06110	COG0586	Pfam SNARE associated Golgi protein
BN1726_RS06115	COG0560	Phosphoserine phosphatase
BN1726_RS06120	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BN1726_RS06150	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BN1726_RS06205	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BN1726_RS06210	COG3250	beta-galactosidase activity
BN1726_RS06215	COG1609	Transcriptional regulator
BN1726_RS06225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BN1726_RS06230	COG3069	C4-dicarboxylate transmembrane transporter activity
BN1726_RS06250	COG1132	(ABC) transporter
BN1726_RS06255	COG1132	(ABC) transporter
BN1726_RS06330	COG1309	transcriptional regulator
BN1726_RS06345	COG0602	queuosine metabolic process
BN1726_RS06350	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BN1726_RS06350	COG1328	CTP reductase activity
BN1726_RS06355	COG1570	exodeoxyribonuclease VII activity
BN1726_RS06360	COG1722	exodeoxyribonuclease VII activity
BN1726_RS06365	COG2249	NAD(P)H dehydrogenase (quinone) activity
BN1726_RS06370	COG1022	Amp-dependent synthetase and ligase
BN1726_RS06375	COG1970	mechanosensitive ion channel activity
BN1726_RS06400	COG0248	Ppx GppA phosphatase
BN1726_RS06405	COG0436	Aminotransferase
BN1726_RS06470	COG3590	peptidase
BN1726_RS06500	COG1355	regulation of microtubule-based process
BN1726_RS06505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BN1726_RS06520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BN1726_RS06525	COG0009	L-threonylcarbamoyladenylate synthase
BN1726_RS06530	COG0110	maltose O-acetyltransferase activity
BN1726_RS06585	COG1070	Carbohydrate kinase
BN1726_RS06615	COG3507	Belongs to the glycosyl hydrolase 43 family
BN1726_RS06620	COG3507	Belongs to the glycosyl hydrolase 43 family
BN1726_RS06625	COG0395	ABC-type sugar transport system, permease component
BN1726_RS06630	COG1175	transmembrane transport
BN1726_RS06640	COG1609	Transcriptional regulator
BN1726_RS06645	COG1979	alcohol dehydrogenase
BN1726_RS06655	COG2814	Major facilitator Superfamily
BN1726_RS06660	COG2814	Major facilitator Superfamily
BN1726_RS06670	COG0242	peptide deformylase activity
BN1726_RS06695	COG4214	carbohydrate transport
BN1726_RS06715	COG1129	ABC transporter
BN1726_RS06720	COG1940	carbohydrate kinase activity
BN1726_RS06740	COG1946	Acyl-CoA thioesterase
BN1726_RS06750	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BN1726_RS06755	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BN1726_RS06765	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BN1726_RS06770	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BN1726_RS06810	COG1454	alcohol dehydrogenase
BN1726_RS06820	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BN1726_RS06835	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BN1726_RS06850	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BN1726_RS06855	COG1687	branched-chain amino acid
BN1726_RS06860	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BN1726_RS06880	COG0589	response to stress
BN1726_RS06885	COG0791	NLP P60 protein
BN1726_RS06895	COG1705	Flagellar rod assembly protein muramidase FlgJ
BN1726_RS06895	COG3942	CHAP domain
BN1726_RS06900	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BN1726_RS06910	COG5002	protein histidine kinase activity
BN1726_RS06915	COG0704	Plays a role in the regulation of phosphate uptake
BN1726_RS06925	COG1575	Belongs to the MenA family. Type 1 subfamily
BN1726_RS06930	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BN1726_RS06940	COG2814	Major facilitator Superfamily
BN1726_RS06975	COG2197	response regulator
BN1726_RS07000	COG0395	ABC-type sugar transport system, permease component
BN1726_RS07005	COG1175	transmembrane transport
BN1726_RS07030	COG1803	Methylglyoxal synthase
BN1726_RS07030	COG1597	lipid kinase activity
BN1726_RS07035	COG3711	transcriptional antiterminator
BN1726_RS07070	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BN1726_RS07080	COG0328	RNA-DNA hybrid ribonuclease activity
BN1726_RS07105	COG0196	riboflavin kinase activity
BN1726_RS07140	COG1501	Belongs to the glycosyl hydrolase 31 family
BN1726_RS07145	COG0395	ABC-type sugar transport system, permease component
BN1726_RS07150	COG1175	transmembrane transport
BN1726_RS07165	COG3534	alpha-L-arabinofuranosidase
BN1726_RS07185	COG2308	Evidence 4 Homologs of previously reported genes of
BN1726_RS07295	COG0255	Belongs to the universal ribosomal protein uL29 family
BN1726_RS07350	COG1012	belongs to the aldehyde dehydrogenase family
BN1726_RS07350	COG1454	alcohol dehydrogenase
BN1726_RS07385	COG1739	Uncharacterized protein family UPF0029
BN1726_RS07390	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BN1726_RS07410	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BN1726_RS07425	COG0531	amino acid
BN1726_RS07430	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BN1726_RS07525	COG2252	PERMEase
BN1726_RS07550	COG3507	Belongs to the glycosyl hydrolase 43 family
BN1726_RS07555	COG3507	Belongs to the glycosyl hydrolase 43 family
BN1726_RS07630	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BN1726_RS07635	COG4770	biotin carboxylase activity
BN1726_RS07640	COG1268	BioY protein
BN1726_RS07705	COG0250	Participates in transcription elongation, termination and antitermination
BN1726_RS07710	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BN1726_RS07720	COG0436	Aminotransferase
BN1726_RS07745	COG1530	ribonuclease E activity
BN1726_RS07750	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BN1726_RS07775	COG0083	homoserine kinase activity
BN1726_RS07780	COG0460	homoserine dehydrogenase
BN1726_RS07795	COG1309	transcriptional regulator
BN1726_RS07815	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BN1726_RS07820	COG0446	pyridine nucleotide-disulphide oxidoreductase
BN1726_RS07825	COG0167	dihydroorotate dehydrogenase activity
BN1726_RS07860	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BN1726_RS07865	COG0406	alpha-ribazole phosphatase activity
BN1726_RS07865	COG0494	nUDIX hydrolase
BN1726_RS07895	COG0584	glycerophosphoryl diester phosphodiesterase
BN1726_RS07910	COG2986	histidine ammonia-lyase
BN1726_RS07920	COG0179	Fumarylacetoacetate (FAA) hydrolase
BN1726_RS07935	COG1442	glycosyl transferase family 8
BN1726_RS07935	COG1216	Glycosyl transferase, family 2
BN1726_RS07950	COG1368	sulfuric ester hydrolase activity
BN1726_RS07975	COG1216	Glycosyl transferase, family 2
BN1726_RS07990	COG1088	dTDP-glucose 4,6-dehydratase activity
BN1726_RS08065	COG1129	ABC transporter
BN1726_RS08085	COG0084	hydrolase, TatD family'
BN1726_RS08100	COG0395	ABC-type sugar transport system, permease component
BN1726_RS08105	COG1175	transmembrane transport
BN1726_RS08115	COG3940	Belongs to the glycosyl hydrolase 43 family
BN1726_RS08125	COG1609	Transcriptional regulator
BN1726_RS08135	COG3507	Belongs to the glycosyl hydrolase 43 family
BN1726_RS08140	COG3507	Belongs to the glycosyl hydrolase 43 family
BN1726_RS08155	COG1132	(ABC) transporter
BN1726_RS08160	COG1132	(ABC) transporter
BN1726_RS08175	COG1609	Transcriptional regulator
BN1726_RS08250	COG1132	(ABC) transporter
BN1726_RS08270	COG1846	Transcriptional regulator
BN1726_RS08275	COG3645	SOS response
BN1726_RS08295	COG1113	amino acid transport
BN1726_RS08315	COG1113	amino acid transport
BN1726_RS08360	COG1609	Transcriptional regulator
BN1726_RS08370	COG0588	phosphoglycerate mutase activity
BN1726_RS08380	COG0778	Nitroreductase
BN1726_RS08400	COG2826	transposase and inactivated derivatives, IS30 family
BN1726_RS08445	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BN1726_RS08450	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BN1726_RS08455	COG0366	Alpha amylase catalytic
BN1726_RS08465	COG0366	Alpha amylase catalytic
BN1726_RS08470	COG0395	ABC-type sugar transport system, permease component
BN1726_RS08500	COG1609	Transcriptional regulator
BN1726_RS08505	COG1609	Transcriptional regulator
BN1726_RS08510	COG0395	ABC-type sugar transport system, permease component
BN1726_RS08515	COG1175	transmembrane transport
BN1726_RS08540	COG0037	tRNA processing
BN1726_RS08540	COG0590	tRNA wobble adenosine to inosine editing
BN1726_RS08545	COG0025	NhaP-type Na H and K H
BN1726_RS08575	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BN1726_RS08590	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN1726_RS08625	COG3842	ATPase activity
BN1726_RS08630	COG1215	transferase activity, transferring glycosyl groups
BN1726_RS08640	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BN1726_RS08670	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BN1726_RS08705	COG3583	domain protein
BN1726_RS08725	COG0617	tRNA 3'-terminal CCA addition
BN1726_RS08755	COG1475	DNA binding
BN1726_RS08760	COG1192	Involved in chromosome partitioning
BN1726_RS08805	COG0592	DNA-directed DNA polymerase activity
BN1726_RS08820	COG0187	DNA topoisomerase II activity
BN1726_RS08825	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BN1726_RS08830	COG3266	domain, Protein
BN1726_RS08840	COG2826	transposase and inactivated derivatives, IS30 family
BN1726_RS08855	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BN1726_RS08860	COG1522	sequence-specific DNA binding
BN1726_RS08865	COG0436	Aminotransferase
BN1726_RS08910	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BN1726_RS08915	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BN1726_RS08925	COG3265	gluconokinase activity
BN1726_RS08935	COG0783	Belongs to the Dps family
BN1726_RS08940	COG1253	flavin adenine dinucleotide binding
BN1726_RS08955	COG0450	alkyl hydroperoxide reductase
BN1726_RS08975	COG1609	Transcriptional regulator
BN1726_RS08980	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BN1726_RS08990	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BN1726_RS09010	COG0180	Tryptophanyl-tRNA synthetase
BN1726_RS09025	COG0058	SHG alpha-glucan phosphorylase activity
BN1726_RS09070	COG0515	serine threonine protein kinase
BN1726_RS09075	COG0768	penicillin binding
BN1726_RS09135	COG0071	Belongs to the small heat shock protein (HSP20) family
BN1726_RS09160	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BN1726_RS09190	COG0494	nUDIX hydrolase
BN1726_RS09240	COG0343	queuine tRNA-ribosyltransferase activity
BN1726_RS09280	COG0191	fructose-bisphosphate aldolase activity
BN1726_RS09330	COG4974	Belongs to the 'phage' integrase family
BN1726_RS09365	COG0477	Major facilitator Superfamily
BN1726_RS09385	COG0366	Alpha amylase catalytic
BN1726_RS09410	COG1609	Transcriptional regulator
BN1726_RS09450	COG0789	Transcriptional regulator
BN1726_RS09470	COG1028	Short-chain dehydrogenase reductase Sdr
BN1726_RS09475	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BN1726_RS09480	COG1175	transmembrane transport
BN1726_RS09485	COG0395	ABC-type sugar transport system, permease component
BN1726_RS09500	COG1609	Transcriptional regulator
BN1726_RS09505	COG0586	Pfam SNARE associated Golgi protein
BN1726_RS09590	COG0527	aspartate kinase activity
BN1726_RS09620	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BN1726_RS09640	COG1754	DNA topoisomerase type I activity
BN1726_RS09640	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BN1726_RS09695	COG0676	glucose-6-phosphate 1-epimerase activity
BN1726_RS09745	COG0366	Alpha amylase catalytic
BN1726_RS09750	COG3619	membrane
BN1726_RS09765	COG0672	)-iron permease
BN1726_RS09770	COG3470	protein probably involved in high-affinity Fe2 transport
BN1726_RS09785	COG0577	efflux transmembrane transporter activity
BN1726_RS09790	COG1136	(ABC) transporter
BN1726_RS09820	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BN1726_RS09825	COG0363	glucosamine-6-phosphate deaminase activity
BN1726_RS09850	COG1215	transferase activity, transferring glycosyl groups
BN1726_RS09855	COG1309	transcriptional regulator
BN1726_RS09875	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BN1726_RS09885	COG0305	Participates in initiation and elongation during chromosome replication
BN1726_RS09890	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BN1726_RS09895	COG3442	glutamine amidotransferase
BN1726_RS09910	COG1609	Transcriptional regulator
BN1726_RS09920	COG1175	transmembrane transport
BN1726_RS09925	COG0395	ABC-type sugar transport system, permease component
BN1726_RS09950	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BN1726_RS09990	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BN1726_RS09995	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BN1726_RS10000	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BN1726_RS10010	COG1937	Protein conserved in bacteria
BN1726_RS10015	COG1322	Protein conserved in bacteria
BN1726_RS10025	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BN1726_RS10075	COG0287	Prephenate dehydrogenase
BN1726_RS10075	COG1605	Chorismate mutase
BN1726_RS10100	COG0745	RESPONSE REGULATOR receiver
BN1726_RS10115	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BN1726_RS10130	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BN1726_RS10190	COG2826	transposase and inactivated derivatives, IS30 family
BN1726_RS10285	COG0356	it plays a direct role in the translocation of protons across the membrane
BN1726_RS10320	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BN1726_RS10330	COG0545	Peptidyl-prolyl cis-trans isomerase
BN1726_RS10360	COG0251	oxidation-reduction process
BN1726_RS10395	COG3842	ATPase activity
BN1726_RS10410	COG1027	Aspartate ammonia-lyase
BN1726_RS10425	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BN1726_RS10455	COG2270	Major facilitator Superfamily
BN1726_RS10460	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BN1726_RS10460	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BN1726_RS10475	COG0742	ribosomal rna small subunit methyltransferase
BN1726_RS10485	COG0826	peptidase U32
BN1726_RS10490	COG1496	oxidoreductase activity
BN1726_RS10500	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BN1726_RS10510	COG3579	cysteine-type endopeptidase activity
BN1726_RS10515	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BN1726_RS10520	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BN1726_RS10525	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BN1726_RS10530	COG5002	protein histidine kinase activity
BN1726_RS10535	COG0745	RESPONSE REGULATOR receiver
BN1726_RS10560	COG1704	LemA family
BN1726_RS10585	COG1957	nucleoside hydrolase
BN1726_RS10595	COG1653	transport
BN1726_RS10625	COG1175	transmembrane transport
BN1726_RS10630	COG0395	ABC-type sugar transport system, permease component
BN1726_RS10655	COG1837	Belongs to the UPF0109 family
BN1726_RS10690	COG0505	Belongs to the CarA family
BN1726_RS10695	COG0488	(ABC) transporter
BN1726_RS10710	COG0440	acetolactate synthase activity
BN1726_RS10750	COG0667	Aldo Keto reductase
BN1726_RS10790	COG2348	transferase activity, transferring amino-acyl groups
BN1726_RS10835	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BN1726_RS10840	COG1609	Transcriptional regulator
BN1726_RS10865	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BN1726_RS10880	COG0577	efflux transmembrane transporter activity
BN1726_RS10900	COG2814	Major facilitator Superfamily
BN1726_RS10905	COG4988	ABC transporter
BN1726_RS10910	COG2814	Major facilitator Superfamily
BN1726_RS10920	COG1653	transport
BN1726_RS10925	COG1175	transmembrane transport
BN1726_RS10930	COG0395	ABC-type sugar transport system, permease component
BN1726_RS10945	COG3867	Arabinogalactan endo-beta-1,4-galactanase
BN1726_RS10955	COG0656	L-ascorbic acid biosynthetic process
BN1726_RS10975	COG2814	Major facilitator Superfamily
BN1726_RS11005	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BN1726_RS11015	COG2826	transposase and inactivated derivatives, IS30 family
BN1726_RS11040	COG4974	Belongs to the 'phage' integrase family
BN1726_RS11065	COG1216	Glycosyl transferase, family 2
BN1726_RS11075	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BN1726_RS11085	COG0438	transferase activity, transferring glycosyl groups
BN1726_RS11095	COG0438	transferase activity, transferring glycosyl groups