locus-tag	class	description
HUE62_RS00010	COG2814	Major facilitator Superfamily
HUE62_RS00015	COG2814	Major facilitator Superfamily
HUE62_RS00025	COG0242	peptide deformylase activity
HUE62_RS00040	COG1940	carbohydrate kinase activity
HUE62_RS00065	COG1136	(ABC) transporter
HUE62_RS00065	COG0577	efflux transmembrane transporter activity
HUE62_RS00070	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUE62_RS00070	COG1136	(ABC) transporter
HUE62_RS00120	COG1946	Acyl-CoA thioesterase
HUE62_RS00130	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUE62_RS00135	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUE62_RS00145	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE62_RS00150	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HUE62_RS00190	COG1454	alcohol dehydrogenase
HUE62_RS00195	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUE62_RS00210	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUE62_RS00245	COG1192	Involved in chromosome partitioning
HUE62_RS00285	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUE62_RS00330	COG1131	(ABC) transporter
HUE62_RS00435	COG4585	Histidine kinase
HUE62_RS00440	COG2197	response regulator
HUE62_RS00455	COG1505	serine-type exopeptidase activity
HUE62_RS00480	COG4585	Histidine kinase
HUE62_RS00520	COG1131	(ABC) transporter
HUE62_RS00530	COG1132	(ABC) transporter
HUE62_RS00535	COG1136	(ABC) transporter
HUE62_RS00535	COG0577	efflux transmembrane transporter activity
HUE62_RS00545	COG4585	Histidine kinase
HUE62_RS00575	COG4974	Belongs to the 'phage' integrase family
HUE62_RS00615	COG0577	efflux transmembrane transporter activity
HUE62_RS00620	COG1136	(ABC) transporter
HUE62_RS00625	COG5002	protein histidine kinase activity
HUE62_RS00680	COG0577	efflux transmembrane transporter activity
HUE62_RS00760	COG2814	Major facilitator Superfamily
HUE62_RS00810	COG1136	(ABC) transporter
HUE62_RS00835	COG2814	Major facilitator Superfamily
HUE62_RS00870	COG1609	Transcriptional regulator
HUE62_RS00875	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUE62_RS00895	COG1116	anion transmembrane transporter activity
HUE62_RS00925	COG2348	transferase activity, transferring amino-acyl groups
HUE62_RS00970	COG0667	Aldo Keto reductase
HUE62_RS01010	COG0440	acetolactate synthase activity
HUE62_RS01020	COG1487	ribonuclease activity
HUE62_RS01040	COG0505	Belongs to the CarA family
HUE62_RS01070	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE62_RS01070	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE62_RS01100	COG1837	Belongs to the UPF0109 family
HUE62_RS01125	COG1957	nucleoside hydrolase
HUE62_RS01150	COG1704	LemA family
HUE62_RS01175	COG0745	RESPONSE REGULATOR receiver
HUE62_RS01180	COG5002	protein histidine kinase activity
HUE62_RS01185	COG0477	Major facilitator Superfamily
HUE62_RS01190	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUE62_RS01195	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUE62_RS01200	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUE62_RS01205	COG3579	cysteine-type endopeptidase activity
HUE62_RS01215	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUE62_RS01225	COG1496	oxidoreductase activity
HUE62_RS01230	COG0826	peptidase U32
HUE62_RS01240	COG0742	ribosomal rna small subunit methyltransferase
HUE62_RS01245	COG1301	dicarboxylic acid transport
HUE62_RS01275	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUE62_RS01275	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUE62_RS01280	COG2270	Major facilitator Superfamily
HUE62_RS01330	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUE62_RS01345	COG1027	Aspartate ammonia-lyase
HUE62_RS01360	COG3842	ATPase activity
HUE62_RS01395	COG0251	oxidation-reduction process
HUE62_RS01445	COG0545	Peptidyl-prolyl cis-trans isomerase
HUE62_RS01455	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUE62_RS01490	COG0356	it plays a direct role in the translocation of protons across the membrane
HUE62_RS01570	COG0582	viral genome integration into host DNA
HUE62_RS01620	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUE62_RS01635	COG0745	RESPONSE REGULATOR receiver
HUE62_RS01720	COG1322	Protein conserved in bacteria
HUE62_RS01725	COG1937	Protein conserved in bacteria
HUE62_RS01735	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE62_RS01775	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUE62_RS01785	COG1131	(ABC) transporter
HUE62_RS01830	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUE62_RS01850	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUE62_RS01855	COG0305	Participates in initiation and elongation during chromosome replication
HUE62_RS01865	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUE62_RS01890	COG1309	transcriptional regulator
HUE62_RS01895	COG1216	Glycosyl transferase, family 2
HUE62_RS01930	COG0363	glucosamine-6-phosphate deaminase activity
HUE62_RS01935	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUE62_RS01965	COG1136	(ABC) transporter
HUE62_RS01970	COG0577	efflux transmembrane transporter activity
HUE62_RS01985	COG3470	protein probably involved in high-affinity Fe2 transport
HUE62_RS01990	COG0672	)-iron permease
HUE62_RS02010	COG3619	membrane
HUE62_RS02035	COG3152	Membrane
HUE62_RS02085	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE62_RS02115	COG1754	DNA topoisomerase type I activity
HUE62_RS02115	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUE62_RS02155	COG0527	aspartate kinase activity
HUE62_RS02230	COG0586	Pfam SNARE associated Golgi protein
HUE62_RS02235	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE62_RS02260	COG0789	Transcriptional regulator
HUE62_RS02325	COG1268	BioY protein
HUE62_RS02330	COG1122	ATPase activity
HUE62_RS02335	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HUE62_RS02355	COG0477	Major facilitator Superfamily
HUE62_RS02405	COG0191	fructose-bisphosphate aldolase activity
HUE62_RS02430	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUE62_RS02430	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUE62_RS02435	COG1397	ADP-ribosylglycohydrolase
HUE62_RS02440	COG2188	Transcriptional regulator
HUE62_RS02455	COG4974	Belongs to the 'phage' integrase family
HUE62_RS02460	COG2226	methyltransferase
HUE62_RS02505	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUE62_RS02520	COG0804	urea catabolic process
HUE62_RS02530	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HUE62_RS02550	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE62_RS02570	COG0343	queuine tRNA-ribosyltransferase activity
HUE62_RS02610	COG0071	Belongs to the small heat shock protein (HSP20) family
HUE62_RS02640	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE62_RS02640	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE62_RS02645	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUE62_RS02690	COG0768	penicillin binding
HUE62_RS02695	COG0515	serine threonine protein kinase
HUE62_RS02735	COG0058	SHG alpha-glucan phosphorylase activity
HUE62_RS02755	COG2197	response regulator
HUE62_RS02765	COG0180	Tryptophanyl-tRNA synthetase
HUE62_RS02780	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUE62_RS02800	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUE62_RS02815	COG1373	ATPase (AAA superfamily
HUE62_RS02850	COG1716	ATPase activity
HUE62_RS02850	COG1131	(ABC) transporter
HUE62_RS02850	COG0842	Transport permease protein
HUE62_RS02855	COG1716	ATPase activity
HUE62_RS02855	COG1131	(ABC) transporter
HUE62_RS02855	COG0842	Transport permease protein
HUE62_RS02865	COG1253	flavin adenine dinucleotide binding
HUE62_RS02870	COG0783	Belongs to the Dps family
HUE62_RS02895	COG1737	Transcriptional regulator
HUE62_RS02910	COG3639	organic phosphonate transmembrane transporter activity
HUE62_RS02960	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUE62_RS02970	COG0542	response to heat
HUE62_RS02975	COG3266	domain, Protein
HUE62_RS02980	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE62_RS02985	COG0187	DNA topoisomerase II activity
HUE62_RS03000	COG0592	DNA-directed DNA polymerase activity
HUE62_RS03040	COG1192	Involved in chromosome partitioning
HUE62_RS03045	COG1475	DNA binding
HUE62_RS03070	COG0617	tRNA 3'-terminal CCA addition
HUE62_RS03090	COG3583	domain protein
HUE62_RS03115	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE62_RS03140	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUE62_RS03150	COG1215	transferase activity, transferring glycosyl groups
HUE62_RS03155	COG3842	ATPase activity
HUE62_RS03165	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE62_RS03175	COG1263	PTS System
HUE62_RS03175	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE62_RS03180	COG1263	PTS System
HUE62_RS03180	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE62_RS03180	COG2190	(PTS) system
HUE62_RS03190	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUE62_RS03220	COG1349	DNA-binding transcription factor activity
HUE62_RS03225	COG1486	melibiose metabolic process
HUE62_RS03230	COG1653	transport
HUE62_RS03235	COG1175	transmembrane transport
HUE62_RS03240	COG3833	ABC-type maltose transport systems, permease component
HUE62_RS03270	COG0025	NhaP-type Na H and K H
HUE62_RS03275	COG0037	tRNA processing
HUE62_RS03275	COG0590	tRNA wobble adenosine to inosine editing
HUE62_RS03295	COG1175	transmembrane transport
HUE62_RS03300	COG0395	ABC-type sugar transport system, permease component
HUE62_RS03305	COG0366	Alpha amylase catalytic
HUE62_RS03310	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUE62_RS03315	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUE62_RS03365	COG0778	Nitroreductase
HUE62_RS03375	COG0588	phosphoglycerate mutase activity
HUE62_RS03405	COG1113	amino acid transport
HUE62_RS03410	COG1136	(ABC) transporter
HUE62_RS03410	COG0577	efflux transmembrane transporter activity
HUE62_RS03420	COG1113	amino acid transport
HUE62_RS03425	COG1846	Transcriptional regulator
HUE62_RS03435	COG1132	(ABC) transporter
HUE62_RS03500	COG4166	transmembrane transport
HUE62_RS03530	COG1132	(ABC) transporter
HUE62_RS03535	COG1132	(ABC) transporter
HUE62_RS03545	COG3177	Filamentation induced by cAMP protein fic
HUE62_RS03555	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HUE62_RS03565	COG0477	Major facilitator Superfamily
HUE62_RS03580	COG0084	hydrolase, TatD family'
HUE62_RS03600	COG1129	ABC transporter
HUE62_RS03620	COG1088	dTDP-glucose 4,6-dehydratase activity
HUE62_RS03625	COG1216	Glycosyl transferase, family 2
HUE62_RS03635	COG1216	Glycosyl transferase, family 2
HUE62_RS03650	COG1216	Glycosyl transferase, family 2
HUE62_RS03660	COG0463	Glycosyl transferase, family 2
HUE62_RS03685	COG1175	transmembrane transport
HUE62_RS03690	COG0395	ABC-type sugar transport system, permease component
HUE62_RS03715	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUE62_RS03735	COG0584	glycerophosphoryl diester phosphodiesterase
HUE62_RS03740	COG1175	transmembrane transport
HUE62_RS03745	COG0395	ABC-type sugar transport system, permease component
HUE62_RS03795	COG3842	ATPase activity
HUE62_RS03805	COG0395	ABC-type sugar transport system, permease component
HUE62_RS03845	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE62_RS03860	COG4209	transmembrane transport
HUE62_RS03865	COG0395	ABC-type sugar transport system, permease component
HUE62_RS03875	COG4948	Mandelate Racemase Muconate Lactonizing
HUE62_RS03885	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE62_RS03890	COG4154	Belongs to the RbsD FucU family
HUE62_RS03905	COG3250	beta-galactosidase activity
HUE62_RS03925	COG0406	alpha-ribazole phosphatase activity
HUE62_RS03925	COG0494	nUDIX hydrolase
HUE62_RS03930	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUE62_RS03955	COG0167	dihydroorotate dehydrogenase activity
HUE62_RS03960	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUE62_RS03965	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUE62_RS03975	COG0583	DNA-binding transcription factor activity
HUE62_RS03985	COG1309	transcriptional regulator
HUE62_RS04030	COG0460	homoserine dehydrogenase
HUE62_RS04035	COG0083	homoserine kinase activity
HUE62_RS04050	COG1136	(ABC) transporter
HUE62_RS04060	COG1609	Transcriptional regulator
HUE62_RS04065	COG4948	Mandelate Racemase Muconate Lactonizing
HUE62_RS04085	COG4154	Belongs to the RbsD FucU family
HUE62_RS04095	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE62_RS04100	COG1530	ribonuclease E activity
HUE62_RS04125	COG0436	Aminotransferase
HUE62_RS04135	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUE62_RS04140	COG0250	Participates in transcription elongation, termination and antitermination
HUE62_RS04195	COG1414	Transcriptional regulator
HUE62_RS04205	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE62_RS04215	COG1917	Cupin 2, conserved barrel domain protein
HUE62_RS04215	COG4977	sequence-specific DNA binding
HUE62_RS04220	COG0673	inositol 2-dehydrogenase activity
HUE62_RS04225	COG0673	inositol 2-dehydrogenase activity
HUE62_RS04230	COG1082	Xylose isomerase domain protein TIM barrel
HUE62_RS04235	COG2814	Major facilitator Superfamily
HUE62_RS04245	COG2814	Major facilitator Superfamily
HUE62_RS04250	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE62_RS04250	COG0574	Belongs to the PEP-utilizing enzyme family
HUE62_RS04255	COG3959	Transketolase, thiamine diphosphate binding domain
HUE62_RS04290	COG4770	biotin carboxylase activity
HUE62_RS04295	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUE62_RS04305	COG1621	beta-fructofuranosidase activity
HUE62_RS04310	COG0395	ABC-type sugar transport system, permease component
HUE62_RS04315	COG1175	transmembrane transport
HUE62_RS04455	COG1122	ATPase activity
HUE62_RS04460	COG1132	(ABC) transporter
HUE62_RS04475	COG2252	PERMEase
HUE62_RS04540	COG0626	cystathionine gamma-synthase activity
HUE62_RS04565	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUE62_RS04570	COG0531	amino acid
HUE62_RS04585	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUE62_RS04595	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE62_RS04600	COG1739	Uncharacterized protein family UPF0029
HUE62_RS04635	COG1454	alcohol dehydrogenase
HUE62_RS04635	COG1012	belongs to the aldehyde dehydrogenase family
HUE62_RS04645	COG3527	Alpha-acetolactate decarboxylase
HUE62_RS04695	COG0255	Belongs to the universal ribosomal protein uL29 family
HUE62_RS04800	COG2308	Evidence 4 Homologs of previously reported genes of
HUE62_RS04825	COG1175	transmembrane transport
HUE62_RS04830	COG0395	ABC-type sugar transport system, permease component
HUE62_RS04870	COG0196	riboflavin kinase activity
HUE62_RS04895	COG0328	RNA-DNA hybrid ribonuclease activity
HUE62_RS04905	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE62_RS04935	COG1803	Methylglyoxal synthase
HUE62_RS04935	COG1597	lipid kinase activity
HUE62_RS04970	COG2197	response regulator
HUE62_RS05010	COG2814	Major facilitator Superfamily
HUE62_RS05020	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUE62_RS05050	COG1575	Belongs to the MenA family. Type 1 subfamily
HUE62_RS05080	COG0704	Plays a role in the regulation of phosphate uptake
HUE62_RS05085	COG5002	protein histidine kinase activity
HUE62_RS05095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUE62_RS05100	COG3942	CHAP domain
HUE62_RS05100	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUE62_RS05110	COG0791	NLP P60 protein
HUE62_RS05115	COG0589	response to stress
HUE62_RS05135	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE62_RS05150	COG0577	efflux transmembrane transporter activity
HUE62_RS05180	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUE62_RS05185	COG0560	Phosphoserine phosphatase
HUE62_RS05190	COG0586	Pfam SNARE associated Golgi protein
HUE62_RS05200	COG4122	O-methyltransferase activity
HUE62_RS05270	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE62_RS05315	COG4641	Protein conserved in bacteria
HUE62_RS05315	COG0438	transferase activity, transferring glycosyl groups
HUE62_RS05330	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUE62_RS05340	COG0438	transferase activity, transferring glycosyl groups
HUE62_RS05355	COG0297	glycogen (starch) synthase activity
HUE62_RS05360	COG0438	transferase activity, transferring glycosyl groups
HUE62_RS05365	COG1088	dTDP-glucose 4,6-dehydratase activity
HUE62_RS05400	COG0758	DNA mediated transformation
HUE62_RS05415	COG0489	protein tyrosine kinase activity
HUE62_RS05425	COG1484	DNA-dependent DNA replication
HUE62_RS05505	COG0095	Lipoate-protein ligase
HUE62_RS05515	COG4499	WXG100 protein secretion system (Wss), protein YukC
HUE62_RS05515	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUE62_RS05520	COG1902	pentaerythritol trinitrate reductase activity
HUE62_RS05525	COG0167	dihydroorotate dehydrogenase activity
HUE62_RS05530	COG1349	DNA-binding transcription factor activity
HUE62_RS05540	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUE62_RS05545	COG0477	Major facilitator Superfamily
HUE62_RS05560	COG0477	Major facilitator Superfamily
HUE62_RS05585	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUE62_RS05595	COG2814	Major facilitator Superfamily
HUE62_RS05615	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUE62_RS05665	COG0714	Associated with various cellular activities
HUE62_RS05685	COG0210	DNA helicase
HUE62_RS05705	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUE62_RS05720	COG1653	transport
HUE62_RS05725	COG0395	ABC-type sugar transport system, permease component
HUE62_RS05730	COG1175	transmembrane transport
HUE62_RS05755	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUE62_RS05760	COG2884	Cell division ATP-binding protein ftsE
HUE62_RS05765	COG2177	Part of the ABC transporter FtsEX involved in
HUE62_RS05770	COG1388	LysM domain
HUE62_RS05770	COG3942	CHAP domain
HUE62_RS05805	COG0564	pseudouridine synthase activity
HUE62_RS05830	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUE62_RS05835	COG0747	negative chemotaxis
HUE62_RS05855	COG4608	Belongs to the ABC transporter superfamily
HUE62_RS05880	COG0626	cystathionine gamma-synthase activity
HUE62_RS05890	COG0514	ATP-dependent DNA helicase (RecQ)
HUE62_RS05905	COG0531	amino acid
HUE62_RS05910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUE62_RS05920	COG0358	DNA primase activity
HUE62_RS05935	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUE62_RS05955	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUE62_RS05970	COG0577	efflux transmembrane transporter activity
HUE62_RS05970	COG1136	(ABC) transporter
HUE62_RS05980	COG0577	efflux transmembrane transporter activity
HUE62_RS05980	COG0577	efflux transmembrane transporter activity
HUE62_RS05985	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUE62_RS05995	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUE62_RS06000	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUE62_RS06045	COG0701	Predicted permease
HUE62_RS06060	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUE62_RS06070	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUE62_RS06075	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUE62_RS06080	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUE62_RS06100	COG1012	belongs to the aldehyde dehydrogenase family
HUE62_RS06130	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE62_RS06140	COG0402	S-adenosylhomocysteine deaminase activity
HUE62_RS06145	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUE62_RS06150	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUE62_RS06160	COG0667	Aldo Keto reductase
HUE62_RS06200	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUE62_RS06220	COG0436	Aminotransferase
HUE62_RS06240	COG0385	Bile acid
HUE62_RS06305	COG0583	DNA-binding transcription factor activity
HUE62_RS06330	COG1063	alcohol dehydrogenase
HUE62_RS06340	COG2801	Transposase and inactivated derivatives
HUE62_RS06400	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUE62_RS06455	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE62_RS06460	COG4721	ABC-type cobalt transport system, permease component
HUE62_RS06465	COG1122	ATPase activity
HUE62_RS06475	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE62_RS06545	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUE62_RS06550	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE62_RS06575	COG0647	UMP catabolic process
HUE62_RS06600	COG0497	DNA recombination
HUE62_RS06605	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE62_RS06610	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HUE62_RS06615	COG2814	Major facilitator Superfamily
HUE62_RS06655	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUE62_RS06685	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUE62_RS06725	COG0667	Aldo Keto reductase
HUE62_RS06760	COG1760	l-serine dehydratase
HUE62_RS06770	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUE62_RS06795	COG1316	TRANSCRIPTIONal
HUE62_RS06825	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUE62_RS06835	COG2205	protein histidine kinase activity
HUE62_RS06840	COG0745	RESPONSE REGULATOR receiver
HUE62_RS06850	COG1329	Transcriptional regulator
HUE62_RS06865	COG1121	(ABC) transporter
HUE62_RS06870	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUE62_RS06880	COG0539	negative regulation of cytoplasmic translation
HUE62_RS06890	COG0577	efflux transmembrane transporter activity
HUE62_RS06890	COG1136	(ABC) transporter
HUE62_RS06905	COG2197	response regulator
HUE62_RS06925	COG0469	pyruvate kinase activity
HUE62_RS06945	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUE62_RS06950	COG1051	belongs to the nudix hydrolase family
HUE62_RS06975	COG0519	Catalyzes the synthesis of GMP from XMP
HUE62_RS07000	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUE62_RS07005	COG0280	phosphate acetyltransferase
HUE62_RS07005	COG0857	belongs to the CobB CobQ family
HUE62_RS07020	COG0406	alpha-ribazole phosphatase activity
HUE62_RS07025	COG0799	negative regulation of ribosome biogenesis
HUE62_RS07045	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUE62_RS07045	COG2755	lipolytic protein G-D-S-L family
HUE62_RS07085	COG2011	ABC-type metal ion transport system permease component
HUE62_RS07090	COG1473	amidohydrolase
HUE62_RS07105	COG1882	Formate acetyltransferase
HUE62_RS07110	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUE62_RS07170	COG1611	Belongs to the LOG family
HUE62_RS07185	COG1053	succinate dehydrogenase
HUE62_RS07190	COG0758	DNA mediated transformation
HUE62_RS07210	COG2873	o-acetylhomoserine
HUE62_RS07215	COG1136	(ABC) transporter
HUE62_RS07220	COG1136	(ABC) transporter
HUE62_RS07220	COG0577	efflux transmembrane transporter activity
HUE62_RS07225	COG2197	response regulator
HUE62_RS07240	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUE62_RS07245	COG0012	GTP binding
HUE62_RS07295	COG3177	Filamentation induced by cAMP protein fic
HUE62_RS07340	COG1309	transcriptional regulator
HUE62_RS07345	COG2814	Major facilitator Superfamily
HUE62_RS07355	COG0515	serine threonine protein kinase
HUE62_RS07355	COG2815	serine threonine protein kinase
HUE62_RS07435	COG2233	PERMEase
HUE62_RS07440	COG0513	Belongs to the DEAD box helicase family
HUE62_RS07455	COG0366	Alpha amylase catalytic
HUE62_RS07460	COG0306	phosphate transporter
HUE62_RS07470	COG2197	response regulator
HUE62_RS07475	COG4585	Histidine kinase
HUE62_RS07480	COG1131	(ABC) transporter
HUE62_RS07525	COG3340	Belongs to the peptidase S51 family
HUE62_RS07530	COG1335	isochorismatase
HUE62_RS07555	COG3655	Transcriptional regulator
HUE62_RS07585	COG0577	efflux transmembrane transporter activity
HUE62_RS07585	COG1136	(ABC) transporter
HUE62_RS07595	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUE62_RS07675	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUE62_RS07690	COG0719	Fe-S assembly protein
HUE62_RS07695	COG0396	ATPase activity
HUE62_RS07700	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUE62_RS07710	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE62_RS07730	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUE62_RS07735	COG0537	adenosine 5'-monophosphoramidase activity
HUE62_RS07740	COG1702	phosphate starvation-inducible protein PhoH
HUE62_RS07765	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUE62_RS07790	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUE62_RS07800	COG2860	membrane
HUE62_RS07820	COG1929	Belongs to the glycerate kinase type-1 family
HUE62_RS07825	COG1609	Transcriptional regulator
HUE62_RS07830	COG0069	glutamate synthase activity
HUE62_RS07830	COG0070	glutamate synthase
HUE62_RS07830	COG0067	glutamate synthase
HUE62_RS07840	COG4166	transmembrane transport
HUE62_RS07855	COG0297	glycogen (starch) synthase activity
HUE62_RS07860	COG1119	ATPase activity
HUE62_RS07875	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUE62_RS07895	COG4221	oxidoreductase activity
HUE62_RS07985	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUE62_RS08010	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUE62_RS08015	COG0284	orotidine-5'-phosphate decarboxylase activity
HUE62_RS08025	COG0167	dihydroorotate dehydrogenase activity
HUE62_RS08045	COG0583	DNA-binding transcription factor activity
HUE62_RS08070	COG3189	MarR family transcriptional regulator
HUE62_RS08100	COG3189	MarR family transcriptional regulator
HUE62_RS08110	COG0833	amino acid
HUE62_RS08125	COG0706	membrane insertase activity
HUE62_RS08130	COG1051	belongs to the nudix hydrolase family
HUE62_RS08200	COG3293	Transposase
HUE62_RS08215	COG3293	Transposase
HUE62_RS08285	COG0833	amino acid
HUE62_RS08295	COG2135	peptidase activity
HUE62_RS08300	COG0133	tryptophan synthase activity
HUE62_RS08315	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUE62_RS08330	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUE62_RS08350	COG1716	ATPase activity
HUE62_RS08370	COG1136	(ABC) transporter
HUE62_RS08415	COG1187	pseudouridine synthase activity
HUE62_RS08420	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE62_RS08445	COG0045	succinate-CoA ligase (ADP-forming) activity
HUE62_RS08530	COG4974	Belongs to the 'phage' integrase family
HUE62_RS08825	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUE62_RS08840	COG0436	Aminotransferase
HUE62_RS08855	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUE62_RS08880	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUE62_RS08920	COG1136	(ABC) transporter
HUE62_RS08920	COG0577	efflux transmembrane transporter activity
HUE62_RS08925	COG1136	(ABC) transporter
HUE62_RS08925	COG0577	efflux transmembrane transporter activity
HUE62_RS08940	COG0745	RESPONSE REGULATOR receiver
HUE62_RS08945	COG2205	protein histidine kinase activity
HUE62_RS08970	COG4221	oxidoreductase activity
HUE62_RS08975	COG0488	(ABC) transporter
HUE62_RS08990	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUE62_RS09020	COG0575	Belongs to the CDS family
HUE62_RS09060	COG0516	GMP reductase activity
HUE62_RS09090	COG2197	response regulator
HUE62_RS09095	COG4585	Histidine kinase
HUE62_RS09175	COG0456	acetyltransferase
HUE62_RS09185	COG0802	atpase or kinase
HUE62_RS09200	COG1555	photosystem II stabilization
HUE62_RS09200	COG1596	polysaccharide export
HUE62_RS09210	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE62_RS09215	COG0598	Magnesium transport protein CorA
HUE62_RS09220	COG0406	alpha-ribazole phosphatase activity
HUE62_RS09250	COG5002	protein histidine kinase activity
HUE62_RS09250	COG3850	Histidine kinase
HUE62_RS09275	COG1131	(ABC) transporter
HUE62_RS09290	COG1136	(ABC) transporter
HUE62_RS09290	COG0577	efflux transmembrane transporter activity
HUE62_RS09345	COG4974	Belongs to the 'phage' integrase family
HUE62_RS09405	COG0477	Major facilitator Superfamily
HUE62_RS09415	COG2977	Belongs to the P-Pant transferase superfamily
HUE62_RS09445	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUE62_RS09470	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE62_RS09480	COG1201	RNA secondary structure unwinding
HUE62_RS09485	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUE62_RS09495	COG0187	DNA topoisomerase II activity
HUE62_RS09500	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUE62_RS09510	COG0142	geranyltranstransferase activity
HUE62_RS09530	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUE62_RS09545	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUE62_RS09570	COG1396	sequence-specific DNA binding
HUE62_RS09605	COG2357	RelA SpoT domain protein
HUE62_RS09615	COG0670	Belongs to the BI1 family
HUE62_RS09665	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUE62_RS09685	COG0708	Exodeoxyribonuclease III
HUE62_RS09695	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE62_RS09700	COG0601	transmembrane transport
HUE62_RS09705	COG4166	transmembrane transport
HUE62_RS09715	COG0577	efflux transmembrane transporter activity
HUE62_RS09715	COG1136	(ABC) transporter
HUE62_RS09720	COG0577	efflux transmembrane transporter activity
HUE62_RS09730	COG0287	Prephenate dehydrogenase
HUE62_RS09745	COG1217	gtp-binding protein TYPA
HUE62_RS09760	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUE62_RS09765	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUE62_RS09775	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUE62_RS09780	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUE62_RS09805	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUE62_RS09820	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUE62_RS09830	COG2017	converts alpha-aldose to the beta-anomer
HUE62_RS09835	COG2017	converts alpha-aldose to the beta-anomer
HUE62_RS09845	COG1595	DNA-templated transcription, initiation
HUE62_RS09860	COG1196	nuclear chromosome segregation
HUE62_RS09865	COG0285	dihydrofolate synthase activity
HUE62_RS09875	COG0006	proline dipeptidase activity
HUE62_RS09890	COG0395	ABC-type sugar transport system, permease component
HUE62_RS09895	COG1175	transmembrane transport
HUE62_RS09920	COG1940	carbohydrate kinase activity
HUE62_RS09950	COG4172	Belongs to the ABC transporter superfamily
HUE62_RS09960	COG0601	transmembrane transport
HUE62_RS09965	COG4166	transmembrane transport
HUE62_RS09990	COG3657	addiction module killer protein
HUE62_RS09995	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE62_RS10060	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUE62_RS10070	COG0768	penicillin binding
HUE62_RS10095	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE62_RS10125	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUE62_RS10130	COG2813	Specifically methylates the guanine in position
HUE62_RS10135	COG1643	Atp-dependent helicase
HUE62_RS10150	COG0747	negative chemotaxis
HUE62_RS10165	COG2814	Major facilitator Superfamily
HUE62_RS10170	COG0174	glutamine synthetase
HUE62_RS10215	COG0656	L-ascorbic acid biosynthetic process
HUE62_RS10235	COG4716	Myosin-crossreactive antigen
HUE62_RS10245	COG0587	DNA-directed DNA polymerase activity
HUE62_RS10260	COG0577	efflux transmembrane transporter activity
HUE62_RS10260	COG1136	(ABC) transporter
HUE62_RS10290	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUE62_RS10315	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE62_RS10320	COG0352	thiamine-phosphate diphosphorylase activity
HUE62_RS10320	COG0351	phosphomethylpyrimidine kinase
HUE62_RS10360	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE62_RS10370	COG1957	nucleoside hydrolase
HUE62_RS10415	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUE62_RS10450	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUE62_RS10475	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
HUE62_RS10490	COG0765	amino acid transport
HUE62_RS10495	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE62_RS10500	COG1126	abc transporter atp-binding protein
HUE62_RS10515	COG1473	amidohydrolase
HUE62_RS10525	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE62_RS10540	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUE62_RS10555	COG0626	cystathionine gamma-synthase activity
HUE62_RS10560	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE62_RS10565	COG1126	abc transporter atp-binding protein
HUE62_RS10570	COG0765	amino acid transport
HUE62_RS10585	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUE62_RS10590	COG2176	DNA-directed DNA polymerase activity
HUE62_RS10600	COG0284	orotidine-5'-phosphate decarboxylase activity
HUE62_RS10625	COG0577	efflux transmembrane transporter activity
HUE62_RS10625	COG1136	(ABC) transporter
HUE62_RS10660	COG1122	ATPase activity
HUE62_RS10705	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE62_RS10710	COG2814	Major facilitator Superfamily
HUE62_RS10720	COG4581	dead DEAH box helicase
HUE62_RS10725	COG2326	polyphosphate kinase activity
HUE62_RS10735	COG0765	amino acid transport
HUE62_RS10740	COG0765	amino acid transport
HUE62_RS10745	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE62_RS10750	COG1126	abc transporter atp-binding protein
HUE62_RS10775	COG1196	nuclear chromosome segregation
HUE62_RS10790	COG0589	response to stress
HUE62_RS10800	COG1278	Cold shock
HUE62_RS10805	COG2205	protein histidine kinase activity
HUE62_RS10810	COG0745	RESPONSE REGULATOR receiver
HUE62_RS10830	COG1278	Cold shock
HUE62_RS10845	COG0714	Associated with various cellular activities
HUE62_RS10890	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUE62_RS10920	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE62_RS10955	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HUE62_RS10960	COG1518	maintenance of DNA repeat elements
HUE62_RS10985	COG1309	transcriptional regulator
HUE62_RS10990	COG2723	6-phospho-beta-galactosidase activity
HUE62_RS10995	COG4608	Belongs to the ABC transporter superfamily
HUE62_RS11000	COG0444	Belongs to the ABC transporter superfamily
HUE62_RS11005	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE62_RS11045	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUE62_RS11050	COG1518	maintenance of DNA repeat elements
HUE62_RS11085	COG3177	Filamentation induced by cAMP protein fic
HUE62_RS11095	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUE62_RS11100	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE62_RS11105	COG4608	Belongs to the ABC transporter superfamily
HUE62_RS11110	COG0444	Belongs to the ABC transporter superfamily
HUE62_RS11120	COG0747	negative chemotaxis
HUE62_RS11130	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HUE62_RS11135	COG1940	carbohydrate kinase activity
HUE62_RS11145	COG2186	Transcriptional regulator
HUE62_RS11150	COG1609	Transcriptional regulator
HUE62_RS11155	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUE62_RS11160	COG3069	C4-dicarboxylate transmembrane transporter activity
HUE62_RS11180	COG1132	(ABC) transporter
HUE62_RS11185	COG1132	(ABC) transporter
HUE62_RS11195	COG2203	Gaf domain
HUE62_RS11195	COG3706	GGDEF domain
HUE62_RS11195	COG4251	negative regulation of phosphorylation
HUE62_RS11195	COG5001	Diguanylate cyclase
HUE62_RS11295	COG0602	queuosine metabolic process
HUE62_RS11300	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUE62_RS11300	COG1328	CTP reductase activity
HUE62_RS11310	COG1570	exodeoxyribonuclease VII activity
HUE62_RS11315	COG1722	exodeoxyribonuclease VII activity
HUE62_RS11325	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUE62_RS11330	COG1022	Amp-dependent synthetase and ligase
HUE62_RS11360	COG0436	Aminotransferase
HUE62_RS11415	COG3590	peptidase
HUE62_RS11455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE62_RS11470	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUE62_RS11475	COG0009	L-threonylcarbamoyladenylate synthase
HUE62_RS11530	COG1070	Carbohydrate kinase
HUE62_RS11545	COG4214	carbohydrate transport
HUE62_RS11550	COG1129	ABC transporter
HUE62_RS11555	COG4213	ABC transporter substrate-binding protein
HUE62_RS11570	COG0110	maltose O-acetyltransferase activity
HUE62_RS11575	COG3507	Belongs to the glycosyl hydrolase 43 family
HUE62_RS11580	COG3507	Belongs to the glycosyl hydrolase 43 family
HUE62_RS11585	COG0395	ABC-type sugar transport system, permease component
HUE62_RS11600	COG1609	Transcriptional regulator
HUE62_RS11605	COG1979	alcohol dehydrogenase