locus-tag	class	description
HUE67_RS00030	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
HUE67_RS00040	COG1131	(ABC) transporter
HUE67_RS00085	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
HUE67_RS00105	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUE67_RS00110	COG0305	Participates in initiation and elongation during chromosome replication
HUE67_RS00120	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
HUE67_RS00145	COG1309	transcriptional regulator
HUE67_RS00150	COG1216	Glycosyl transferase, family 2
HUE67_RS00185	COG0363	glucosamine-6-phosphate deaminase activity
HUE67_RS00190	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
HUE67_RS00220	COG1136	(ABC) transporter
HUE67_RS00225	COG0577	efflux transmembrane transporter activity
HUE67_RS00240	COG3470	protein probably involved in high-affinity Fe2 transport
HUE67_RS00245	COG0672	)-iron permease
HUE67_RS00265	COG3619	membrane
HUE67_RS00290	COG3152	Membrane
HUE67_RS00340	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE67_RS00370	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
HUE67_RS00370	COG1754	DNA topoisomerase type I activity
HUE67_RS00410	COG0527	aspartate kinase activity
HUE67_RS00485	COG0586	Pfam SNARE associated Golgi protein
HUE67_RS00490	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE67_RS00515	COG0789	Transcriptional regulator
HUE67_RS00580	COG1268	BioY protein
HUE67_RS00585	COG1122	ATPase activity
HUE67_RS00590	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
HUE67_RS00610	COG0477	Major facilitator Superfamily
HUE67_RS00660	COG0191	fructose-bisphosphate aldolase activity
HUE67_RS00685	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUE67_RS00685	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUE67_RS00690	COG1397	ADP-ribosylglycohydrolase
HUE67_RS00695	COG2188	Transcriptional regulator
HUE67_RS00705	COG4974	Belongs to the 'phage' integrase family
HUE67_RS00710	COG2226	methyltransferase
HUE67_RS00755	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
HUE67_RS00770	COG0804	urea catabolic process
HUE67_RS00780	COG3376	Belongs to the NiCoT transporter (TC 2.A.52) family
HUE67_RS00800	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE67_RS00820	COG0343	queuine tRNA-ribosyltransferase activity
HUE67_RS00860	COG0071	Belongs to the small heat shock protein (HSP20) family
HUE67_RS00890	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE67_RS00890	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
HUE67_RS00895	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
HUE67_RS00940	COG0768	penicillin binding
HUE67_RS00945	COG0515	serine threonine protein kinase
HUE67_RS00985	COG0058	SHG alpha-glucan phosphorylase activity
HUE67_RS01005	COG2197	response regulator
HUE67_RS01015	COG0180	Tryptophanyl-tRNA synthetase
HUE67_RS01030	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
HUE67_RS01050	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
HUE67_RS01065	COG1373	ATPase (AAA superfamily
HUE67_RS01100	COG0842	Transport permease protein
HUE67_RS01100	COG1131	(ABC) transporter
HUE67_RS01100	COG1716	ATPase activity
HUE67_RS01110	COG1253	flavin adenine dinucleotide binding
HUE67_RS01115	COG0783	Belongs to the Dps family
HUE67_RS01140	COG1737	Transcriptional regulator
HUE67_RS01155	COG3639	organic phosphonate transmembrane transporter activity
HUE67_RS01205	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
HUE67_RS01215	COG0542	response to heat
HUE67_RS01220	COG3266	domain, Protein
HUE67_RS01225	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE67_RS01230	COG0187	DNA topoisomerase II activity
HUE67_RS01245	COG0592	DNA-directed DNA polymerase activity
HUE67_RS01285	COG1192	Involved in chromosome partitioning
HUE67_RS01290	COG1475	DNA binding
HUE67_RS01315	COG0617	tRNA 3'-terminal CCA addition
HUE67_RS01335	COG3583	domain protein
HUE67_RS01360	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
HUE67_RS01385	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
HUE67_RS01395	COG1215	transferase activity, transferring glycosyl groups
HUE67_RS01400	COG3842	ATPase activity
HUE67_RS01410	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE67_RS01420	COG1263	PTS System
HUE67_RS01420	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE67_RS01425	COG2190	(PTS) system
HUE67_RS01425	COG1263	PTS System
HUE67_RS01425	COG1264	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
HUE67_RS01435	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
HUE67_RS01465	COG1349	DNA-binding transcription factor activity
HUE67_RS01470	COG1486	melibiose metabolic process
HUE67_RS01475	COG1653	transport
HUE67_RS01480	COG1175	transmembrane transport
HUE67_RS01485	COG3833	ABC-type maltose transport systems, permease component
HUE67_RS01515	COG0025	NhaP-type Na H and K H
HUE67_RS01520	COG0037	tRNA processing
HUE67_RS01520	COG0590	tRNA wobble adenosine to inosine editing
HUE67_RS01540	COG1175	transmembrane transport
HUE67_RS01545	COG0395	ABC-type sugar transport system, permease component
HUE67_RS01550	COG0366	Alpha amylase catalytic
HUE67_RS01555	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
HUE67_RS01560	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
HUE67_RS01610	COG0778	Nitroreductase
HUE67_RS01620	COG0588	phosphoglycerate mutase activity
HUE67_RS01650	COG1113	amino acid transport
HUE67_RS01655	COG1136	(ABC) transporter
HUE67_RS01655	COG0577	efflux transmembrane transporter activity
HUE67_RS01665	COG1113	amino acid transport
HUE67_RS01670	COG1846	Transcriptional regulator
HUE67_RS01680	COG1132	(ABC) transporter
HUE67_RS01745	COG4166	transmembrane transport
HUE67_RS01775	COG1132	(ABC) transporter
HUE67_RS01780	COG1132	(ABC) transporter
HUE67_RS01790	COG3177	Filamentation induced by cAMP protein fic
HUE67_RS01800	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HUE67_RS01810	COG0477	Major facilitator Superfamily
HUE67_RS01825	COG0084	hydrolase, TatD family'
HUE67_RS01845	COG1129	ABC transporter
HUE67_RS01865	COG1088	dTDP-glucose 4,6-dehydratase activity
HUE67_RS01870	COG1216	Glycosyl transferase, family 2
HUE67_RS01880	COG1216	Glycosyl transferase, family 2
HUE67_RS01895	COG1216	Glycosyl transferase, family 2
HUE67_RS01905	COG0463	Glycosyl transferase, family 2
HUE67_RS01930	COG1175	transmembrane transport
HUE67_RS01935	COG0395	ABC-type sugar transport system, permease component
HUE67_RS01960	COG0179	Fumarylacetoacetate (FAA) hydrolase
HUE67_RS01980	COG0584	glycerophosphoryl diester phosphodiesterase
HUE67_RS01985	COG1175	transmembrane transport
HUE67_RS01990	COG0395	ABC-type sugar transport system, permease component
HUE67_RS02040	COG3842	ATPase activity
HUE67_RS02050	COG0395	ABC-type sugar transport system, permease component
HUE67_RS02090	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE67_RS02105	COG4209	transmembrane transport
HUE67_RS02110	COG0395	ABC-type sugar transport system, permease component
HUE67_RS02120	COG4948	Mandelate Racemase Muconate Lactonizing
HUE67_RS02130	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE67_RS02135	COG4154	Belongs to the RbsD FucU family
HUE67_RS02150	COG3250	beta-galactosidase activity
HUE67_RS02170	COG0406	alpha-ribazole phosphatase activity
HUE67_RS02170	COG0494	nUDIX hydrolase
HUE67_RS02175	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
HUE67_RS02200	COG0167	dihydroorotate dehydrogenase activity
HUE67_RS02205	COG0446	pyridine nucleotide-disulphide oxidoreductase
HUE67_RS02210	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
HUE67_RS02220	COG0583	DNA-binding transcription factor activity
HUE67_RS02230	COG1309	transcriptional regulator
HUE67_RS02275	COG0460	homoserine dehydrogenase
HUE67_RS02280	COG0083	homoserine kinase activity
HUE67_RS02295	COG1136	(ABC) transporter
HUE67_RS02305	COG1609	Transcriptional regulator
HUE67_RS02310	COG4948	Mandelate Racemase Muconate Lactonizing
HUE67_RS02330	COG4154	Belongs to the RbsD FucU family
HUE67_RS02340	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE67_RS02345	COG1530	ribonuclease E activity
HUE67_RS02370	COG0436	Aminotransferase
HUE67_RS02380	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUE67_RS02385	COG0250	Participates in transcription elongation, termination and antitermination
HUE67_RS02440	COG1414	Transcriptional regulator
HUE67_RS02450	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE67_RS02460	COG4977	sequence-specific DNA binding
HUE67_RS02460	COG1917	Cupin 2, conserved barrel domain protein
HUE67_RS02465	COG0673	inositol 2-dehydrogenase activity
HUE67_RS02470	COG0673	inositol 2-dehydrogenase activity
HUE67_RS02475	COG1082	Xylose isomerase domain protein TIM barrel
HUE67_RS02480	COG2814	Major facilitator Superfamily
HUE67_RS02490	COG2814	Major facilitator Superfamily
HUE67_RS02495	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
HUE67_RS02495	COG0574	Belongs to the PEP-utilizing enzyme family
HUE67_RS02500	COG3959	Transketolase, thiamine diphosphate binding domain
HUE67_RS02530	COG4770	biotin carboxylase activity
HUE67_RS02535	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
HUE67_RS02545	COG1621	beta-fructofuranosidase activity
HUE67_RS02550	COG0395	ABC-type sugar transport system, permease component
HUE67_RS02555	COG1175	transmembrane transport
HUE67_RS02690	COG1122	ATPase activity
HUE67_RS02695	COG1132	(ABC) transporter
HUE67_RS02710	COG2252	PERMEase
HUE67_RS02775	COG0626	cystathionine gamma-synthase activity
HUE67_RS02800	COG0812	UDP-N-acetylmuramate dehydrogenase activity
HUE67_RS02805	COG0531	amino acid
HUE67_RS02820	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUE67_RS02830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE67_RS02835	COG1739	Uncharacterized protein family UPF0029
HUE67_RS02870	COG1454	alcohol dehydrogenase
HUE67_RS02870	COG1012	belongs to the aldehyde dehydrogenase family
HUE67_RS02880	COG3527	Alpha-acetolactate decarboxylase
HUE67_RS02930	COG0255	Belongs to the universal ribosomal protein uL29 family
HUE67_RS03035	COG2308	Evidence 4 Homologs of previously reported genes of
HUE67_RS03060	COG1175	transmembrane transport
HUE67_RS03065	COG0395	ABC-type sugar transport system, permease component
HUE67_RS03105	COG0196	riboflavin kinase activity
HUE67_RS03130	COG0328	RNA-DNA hybrid ribonuclease activity
HUE67_RS03140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
HUE67_RS03170	COG1803	Methylglyoxal synthase
HUE67_RS03170	COG1597	lipid kinase activity
HUE67_RS03205	COG2197	response regulator
HUE67_RS03245	COG2814	Major facilitator Superfamily
HUE67_RS03255	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
HUE67_RS03285	COG1575	Belongs to the MenA family. Type 1 subfamily
HUE67_RS03315	COG0704	Plays a role in the regulation of phosphate uptake
HUE67_RS03320	COG5002	protein histidine kinase activity
HUE67_RS03330	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
HUE67_RS03335	COG1705	Flagellar rod assembly protein muramidase FlgJ
HUE67_RS03335	COG3942	CHAP domain
HUE67_RS03345	COG0791	NLP P60 protein
HUE67_RS03350	COG0589	response to stress
HUE67_RS03370	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE67_RS03385	COG0577	efflux transmembrane transporter activity
HUE67_RS03415	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
HUE67_RS03420	COG0560	Phosphoserine phosphatase
HUE67_RS03425	COG0586	Pfam SNARE associated Golgi protein
HUE67_RS03435	COG4122	O-methyltransferase activity
HUE67_RS03505	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE67_RS03545	COG4641	Protein conserved in bacteria
HUE67_RS03545	COG0438	transferase activity, transferring glycosyl groups
HUE67_RS03560	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
HUE67_RS03570	COG0438	transferase activity, transferring glycosyl groups
HUE67_RS03585	COG0297	glycogen (starch) synthase activity
HUE67_RS03590	COG0438	transferase activity, transferring glycosyl groups
HUE67_RS03595	COG1088	dTDP-glucose 4,6-dehydratase activity
HUE67_RS03630	COG0758	DNA mediated transformation
HUE67_RS03645	COG0489	protein tyrosine kinase activity
HUE67_RS03655	COG1484	DNA-dependent DNA replication
HUE67_RS03730	COG0095	Lipoate-protein ligase
HUE67_RS03740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
HUE67_RS03740	COG4499	WXG100 protein secretion system (Wss), protein YukC
HUE67_RS03745	COG1902	pentaerythritol trinitrate reductase activity
HUE67_RS03750	COG0167	dihydroorotate dehydrogenase activity
HUE67_RS03755	COG1349	DNA-binding transcription factor activity
HUE67_RS03765	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
HUE67_RS03770	COG0477	Major facilitator Superfamily
HUE67_RS03785	COG0477	Major facilitator Superfamily
HUE67_RS03810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
HUE67_RS03820	COG2814	Major facilitator Superfamily
HUE67_RS03840	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
HUE67_RS03890	COG0714	Associated with various cellular activities
HUE67_RS03910	COG0210	DNA helicase
HUE67_RS03930	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
HUE67_RS03945	COG1653	transport
HUE67_RS03950	COG0395	ABC-type sugar transport system, permease component
HUE67_RS03955	COG1175	transmembrane transport
HUE67_RS03980	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
HUE67_RS03985	COG2884	Cell division ATP-binding protein ftsE
HUE67_RS03990	COG2177	Part of the ABC transporter FtsEX involved in
HUE67_RS03995	COG3942	CHAP domain
HUE67_RS03995	COG1388	LysM domain
HUE67_RS04030	COG0564	pseudouridine synthase activity
HUE67_RS04055	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
HUE67_RS04060	COG0747	negative chemotaxis
HUE67_RS04080	COG4608	Belongs to the ABC transporter superfamily
HUE67_RS04105	COG0626	cystathionine gamma-synthase activity
HUE67_RS04115	COG0514	ATP-dependent DNA helicase (RecQ)
HUE67_RS04130	COG0531	amino acid
HUE67_RS04135	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
HUE67_RS04145	COG0358	DNA primase activity
HUE67_RS04160	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUE67_RS04180	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
HUE67_RS04195	COG0577	efflux transmembrane transporter activity
HUE67_RS04195	COG1136	(ABC) transporter
HUE67_RS04205	COG0577	efflux transmembrane transporter activity
HUE67_RS04205	COG0577	efflux transmembrane transporter activity
HUE67_RS04210	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
HUE67_RS04220	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
HUE67_RS04225	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
HUE67_RS04270	COG0701	Predicted permease
HUE67_RS04285	COG0257	Belongs to the bacterial ribosomal protein bL36 family
HUE67_RS04295	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
HUE67_RS04300	COG0267	Belongs to the bacterial ribosomal protein bL33 family
HUE67_RS04305	COG0227	Belongs to the bacterial ribosomal protein bL28 family
HUE67_RS04325	COG1012	belongs to the aldehyde dehydrogenase family
HUE67_RS04355	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE67_RS04365	COG0402	S-adenosylhomocysteine deaminase activity
HUE67_RS04370	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
HUE67_RS04375	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
HUE67_RS04385	COG0667	Aldo Keto reductase
HUE67_RS04425	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
HUE67_RS04445	COG0436	Aminotransferase
HUE67_RS04465	COG0385	Bile acid
HUE67_RS04530	COG0583	DNA-binding transcription factor activity
HUE67_RS04555	COG1063	alcohol dehydrogenase
HUE67_RS04565	COG2801	Transposase and inactivated derivatives
HUE67_RS04625	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
HUE67_RS04680	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
HUE67_RS04685	COG4721	ABC-type cobalt transport system, permease component
HUE67_RS04690	COG1122	ATPase activity
HUE67_RS04700	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
HUE67_RS04770	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
HUE67_RS04775	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
HUE67_RS04800	COG0647	UMP catabolic process
HUE67_RS04825	COG0497	DNA recombination
HUE67_RS04830	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
HUE67_RS04835	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
HUE67_RS04840	COG2814	Major facilitator Superfamily
HUE67_RS04880	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
HUE67_RS04910	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
HUE67_RS04950	COG0667	Aldo Keto reductase
HUE67_RS04985	COG1760	l-serine dehydratase
HUE67_RS04995	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
HUE67_RS05020	COG1316	TRANSCRIPTIONal
HUE67_RS05050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
HUE67_RS05060	COG2205	protein histidine kinase activity
HUE67_RS05065	COG0745	RESPONSE REGULATOR receiver
HUE67_RS05075	COG1329	Transcriptional regulator
HUE67_RS05090	COG1121	(ABC) transporter
HUE67_RS05095	COG0803	Belongs to the bacterial solute-binding protein 9 family
HUE67_RS05105	COG0539	negative regulation of cytoplasmic translation
HUE67_RS05115	COG0577	efflux transmembrane transporter activity
HUE67_RS05115	COG1136	(ABC) transporter
HUE67_RS05130	COG2197	response regulator
HUE67_RS05150	COG0469	pyruvate kinase activity
HUE67_RS05170	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
HUE67_RS05175	COG1051	belongs to the nudix hydrolase family
HUE67_RS05200	COG0519	Catalyzes the synthesis of GMP from XMP
HUE67_RS05225	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
HUE67_RS05230	COG0280	phosphate acetyltransferase
HUE67_RS05230	COG0857	belongs to the CobB CobQ family
HUE67_RS05245	COG0406	alpha-ribazole phosphatase activity
HUE67_RS05250	COG0799	negative regulation of ribosome biogenesis
HUE67_RS05270	COG2755	lipolytic protein G-D-S-L family
HUE67_RS05270	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
HUE67_RS05305	COG2011	ABC-type metal ion transport system permease component
HUE67_RS05310	COG1473	amidohydrolase
HUE67_RS05325	COG1882	Formate acetyltransferase
HUE67_RS05330	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
HUE67_RS05390	COG1611	Belongs to the LOG family
HUE67_RS05405	COG1053	succinate dehydrogenase
HUE67_RS05410	COG0758	DNA mediated transformation
HUE67_RS05430	COG2873	o-acetylhomoserine
HUE67_RS05435	COG1136	(ABC) transporter
HUE67_RS05440	COG1136	(ABC) transporter
HUE67_RS05440	COG0577	efflux transmembrane transporter activity
HUE67_RS05445	COG2197	response regulator
HUE67_RS05460	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUE67_RS05465	COG0012	GTP binding
HUE67_RS05515	COG3177	Filamentation induced by cAMP protein fic
HUE67_RS05560	COG1309	transcriptional regulator
HUE67_RS05565	COG2814	Major facilitator Superfamily
HUE67_RS05575	COG0515	serine threonine protein kinase
HUE67_RS05575	COG2815	serine threonine protein kinase
HUE67_RS05645	COG2233	PERMEase
HUE67_RS05650	COG0513	Belongs to the DEAD box helicase family
HUE67_RS05665	COG0366	Alpha amylase catalytic
HUE67_RS05670	COG0306	phosphate transporter
HUE67_RS05680	COG2197	response regulator
HUE67_RS05685	COG4585	Histidine kinase
HUE67_RS05690	COG1131	(ABC) transporter
HUE67_RS05735	COG3340	Belongs to the peptidase S51 family
HUE67_RS05740	COG1335	isochorismatase
HUE67_RS05765	COG3655	Transcriptional regulator
HUE67_RS05795	COG0577	efflux transmembrane transporter activity
HUE67_RS05795	COG1136	(ABC) transporter
HUE67_RS05805	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
HUE67_RS05885	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
HUE67_RS05900	COG0719	Fe-S assembly protein
HUE67_RS05905	COG0396	ATPase activity
HUE67_RS05910	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
HUE67_RS05920	COG2151	metal-sulfur cluster biosynthetic enzyme
HUE67_RS05940	COG1385	rRNA (uridine-N3-)-methyltransferase activity
HUE67_RS05945	COG0537	adenosine 5'-monophosphoramidase activity
HUE67_RS05950	COG1702	phosphate starvation-inducible protein PhoH
HUE67_RS05975	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
HUE67_RS06000	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
HUE67_RS06010	COG2860	membrane
HUE67_RS06030	COG1929	Belongs to the glycerate kinase type-1 family
HUE67_RS06035	COG1609	Transcriptional regulator
HUE67_RS06040	COG0067	glutamate synthase
HUE67_RS06040	COG0070	glutamate synthase
HUE67_RS06040	COG0069	glutamate synthase activity
HUE67_RS06050	COG4166	transmembrane transport
HUE67_RS06065	COG0297	glycogen (starch) synthase activity
HUE67_RS06070	COG1119	ATPase activity
HUE67_RS06085	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
HUE67_RS06105	COG4221	oxidoreductase activity
HUE67_RS06195	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
HUE67_RS06220	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
HUE67_RS06225	COG0284	orotidine-5'-phosphate decarboxylase activity
HUE67_RS06235	COG0167	dihydroorotate dehydrogenase activity
HUE67_RS06255	COG0583	DNA-binding transcription factor activity
HUE67_RS06280	COG3189	MarR family transcriptional regulator
HUE67_RS06310	COG3189	MarR family transcriptional regulator
HUE67_RS06320	COG0833	amino acid
HUE67_RS06335	COG0706	membrane insertase activity
HUE67_RS06340	COG1051	belongs to the nudix hydrolase family
HUE67_RS06410	COG3293	Transposase
HUE67_RS06425	COG3293	Transposase
HUE67_RS06485	COG0833	amino acid
HUE67_RS06495	COG2135	peptidase activity
HUE67_RS06500	COG0133	tryptophan synthase activity
HUE67_RS06515	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
HUE67_RS06530	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
HUE67_RS06550	COG1716	ATPase activity
HUE67_RS06570	COG1136	(ABC) transporter
HUE67_RS06615	COG1187	pseudouridine synthase activity
HUE67_RS06620	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
HUE67_RS06645	COG0045	succinate-CoA ligase (ADP-forming) activity
HUE67_RS06730	COG4974	Belongs to the 'phage' integrase family
HUE67_RS07020	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
HUE67_RS07035	COG0436	Aminotransferase
HUE67_RS07050	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
HUE67_RS07075	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
HUE67_RS07115	COG1136	(ABC) transporter
HUE67_RS07115	COG0577	efflux transmembrane transporter activity
HUE67_RS07120	COG1136	(ABC) transporter
HUE67_RS07120	COG0577	efflux transmembrane transporter activity
HUE67_RS07135	COG0745	RESPONSE REGULATOR receiver
HUE67_RS07140	COG2205	protein histidine kinase activity
HUE67_RS07165	COG4221	oxidoreductase activity
HUE67_RS07170	COG0488	(ABC) transporter
HUE67_RS07185	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUE67_RS07215	COG0575	Belongs to the CDS family
HUE67_RS07255	COG0516	GMP reductase activity
HUE67_RS07285	COG2197	response regulator
HUE67_RS07290	COG4585	Histidine kinase
HUE67_RS07365	COG0456	acetyltransferase
HUE67_RS07375	COG0802	atpase or kinase
HUE67_RS07390	COG1596	polysaccharide export
HUE67_RS07390	COG1555	photosystem II stabilization
HUE67_RS07400	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE67_RS07405	COG0598	Magnesium transport protein CorA
HUE67_RS07410	COG0406	alpha-ribazole phosphatase activity
HUE67_RS07440	COG3850	Histidine kinase
HUE67_RS07440	COG5002	protein histidine kinase activity
HUE67_RS07465	COG1131	(ABC) transporter
HUE67_RS07480	COG0577	efflux transmembrane transporter activity
HUE67_RS07480	COG1136	(ABC) transporter
HUE67_RS07535	COG4974	Belongs to the 'phage' integrase family
HUE67_RS07595	COG0477	Major facilitator Superfamily
HUE67_RS07605	COG2977	Belongs to the P-Pant transferase superfamily
HUE67_RS07635	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
HUE67_RS07660	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
HUE67_RS07670	COG1201	RNA secondary structure unwinding
HUE67_RS07675	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUE67_RS07685	COG0187	DNA topoisomerase II activity
HUE67_RS07690	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
HUE67_RS07700	COG0142	geranyltranstransferase activity
HUE67_RS07720	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
HUE67_RS07735	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
HUE67_RS07760	COG1396	sequence-specific DNA binding
HUE67_RS07795	COG2357	RelA SpoT domain protein
HUE67_RS07805	COG0670	Belongs to the BI1 family
HUE67_RS07855	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
HUE67_RS07875	COG0708	Exodeoxyribonuclease III
HUE67_RS07885	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE67_RS07890	COG0601	transmembrane transport
HUE67_RS07895	COG4166	transmembrane transport
HUE67_RS07905	COG0577	efflux transmembrane transporter activity
HUE67_RS07905	COG1136	(ABC) transporter
HUE67_RS07910	COG0577	efflux transmembrane transporter activity
HUE67_RS07920	COG0287	Prephenate dehydrogenase
HUE67_RS07935	COG1217	gtp-binding protein TYPA
HUE67_RS07950	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
HUE67_RS07955	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
HUE67_RS07965	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
HUE67_RS07970	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
HUE67_RS07995	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
HUE67_RS08010	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
HUE67_RS08020	COG2017	converts alpha-aldose to the beta-anomer
HUE67_RS08025	COG2017	converts alpha-aldose to the beta-anomer
HUE67_RS08035	COG1595	DNA-templated transcription, initiation
HUE67_RS08050	COG1196	nuclear chromosome segregation
HUE67_RS08055	COG0285	dihydrofolate synthase activity
HUE67_RS08065	COG0006	proline dipeptidase activity
HUE67_RS08080	COG0395	ABC-type sugar transport system, permease component
HUE67_RS08085	COG1175	transmembrane transport
HUE67_RS08110	COG1940	carbohydrate kinase activity
HUE67_RS08140	COG4172	Belongs to the ABC transporter superfamily
HUE67_RS08150	COG0601	transmembrane transport
HUE67_RS08155	COG4166	transmembrane transport
HUE67_RS08180	COG3657	addiction module killer protein
HUE67_RS08185	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE67_RS08250	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
HUE67_RS08260	COG0768	penicillin binding
HUE67_RS08285	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE67_RS08315	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
HUE67_RS08320	COG2813	Specifically methylates the guanine in position
HUE67_RS08325	COG1643	Atp-dependent helicase
HUE67_RS08340	COG0747	negative chemotaxis
HUE67_RS08355	COG2814	Major facilitator Superfamily
HUE67_RS08360	COG0174	glutamine synthetase
HUE67_RS08405	COG0656	L-ascorbic acid biosynthetic process
HUE67_RS08425	COG4716	Myosin-crossreactive antigen
HUE67_RS08435	COG0587	DNA-directed DNA polymerase activity
HUE67_RS08450	COG1136	(ABC) transporter
HUE67_RS08450	COG0577	efflux transmembrane transporter activity
HUE67_RS08480	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
HUE67_RS08505	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE67_RS08510	COG0351	phosphomethylpyrimidine kinase
HUE67_RS08510	COG0352	thiamine-phosphate diphosphorylase activity
HUE67_RS08550	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
HUE67_RS08560	COG1957	nucleoside hydrolase
HUE67_RS08605	COG3480	Lon protease (S16) C-terminal proteolytic domain
HUE67_RS08640	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
HUE67_RS08665	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
HUE67_RS08680	COG0765	amino acid transport
HUE67_RS08685	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE67_RS08690	COG1126	abc transporter atp-binding protein
HUE67_RS08705	COG1473	amidohydrolase
HUE67_RS08715	COG0559	Belongs to the binding-protein-dependent transport system permease family
HUE67_RS08730	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
HUE67_RS08745	COG0626	cystathionine gamma-synthase activity
HUE67_RS08750	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE67_RS08755	COG1126	abc transporter atp-binding protein
HUE67_RS08760	COG0765	amino acid transport
HUE67_RS08775	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
HUE67_RS08780	COG2176	DNA-directed DNA polymerase activity
HUE67_RS08790	COG0284	orotidine-5'-phosphate decarboxylase activity
HUE67_RS08815	COG0577	efflux transmembrane transporter activity
HUE67_RS08815	COG1136	(ABC) transporter
HUE67_RS08850	COG1122	ATPase activity
HUE67_RS08895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
HUE67_RS08900	COG2814	Major facilitator Superfamily
HUE67_RS08910	COG4581	dead DEAH box helicase
HUE67_RS08915	COG2326	polyphosphate kinase activity
HUE67_RS08925	COG0765	amino acid transport
HUE67_RS08930	COG0765	amino acid transport
HUE67_RS08935	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
HUE67_RS08940	COG1126	abc transporter atp-binding protein
HUE67_RS08960	COG1196	nuclear chromosome segregation
HUE67_RS08975	COG0589	response to stress
HUE67_RS08985	COG1278	Cold shock
HUE67_RS08990	COG2205	protein histidine kinase activity
HUE67_RS08995	COG0745	RESPONSE REGULATOR receiver
HUE67_RS09015	COG1278	Cold shock
HUE67_RS09030	COG0714	Associated with various cellular activities
HUE67_RS09075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
HUE67_RS09105	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
HUE67_RS09140	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
HUE67_RS09145	COG1518	maintenance of DNA repeat elements
HUE67_RS09170	COG1309	transcriptional regulator
HUE67_RS09175	COG2723	6-phospho-beta-galactosidase activity
HUE67_RS09180	COG4608	Belongs to the ABC transporter superfamily
HUE67_RS09185	COG0444	Belongs to the ABC transporter superfamily
HUE67_RS09190	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
HUE67_RS09230	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
HUE67_RS09235	COG1518	maintenance of DNA repeat elements
HUE67_RS09270	COG3177	Filamentation induced by cAMP protein fic
HUE67_RS09280	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
HUE67_RS09285	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
HUE67_RS09290	COG4608	Belongs to the ABC transporter superfamily
HUE67_RS09295	COG0444	Belongs to the ABC transporter superfamily
HUE67_RS09305	COG0747	negative chemotaxis
HUE67_RS09315	COG3010	Converts N-acetylmannosamine-6-phosphate (ManNAc-6-P) to N-acetylglucosamine-6-phosphate (GlcNAc-6-P)
HUE67_RS09320	COG1940	carbohydrate kinase activity
HUE67_RS09330	COG2186	Transcriptional regulator
HUE67_RS09335	COG1609	Transcriptional regulator
HUE67_RS09340	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
HUE67_RS09345	COG3069	C4-dicarboxylate transmembrane transporter activity
HUE67_RS09365	COG1132	(ABC) transporter
HUE67_RS09370	COG1132	(ABC) transporter
HUE67_RS09380	COG2203	Gaf domain
HUE67_RS09380	COG3706	GGDEF domain
HUE67_RS09380	COG5001	Diguanylate cyclase
HUE67_RS09380	COG4251	negative regulation of phosphorylation
HUE67_RS09475	COG0602	queuosine metabolic process
HUE67_RS09480	COG1328	CTP reductase activity
HUE67_RS09480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
HUE67_RS09485	COG1570	exodeoxyribonuclease VII activity
HUE67_RS09490	COG1722	exodeoxyribonuclease VII activity
HUE67_RS09500	COG2249	NAD(P)H dehydrogenase (quinone) activity
HUE67_RS09505	COG1022	Amp-dependent synthetase and ligase
HUE67_RS09535	COG0436	Aminotransferase
HUE67_RS09590	COG3590	peptidase
HUE67_RS09630	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
HUE67_RS09645	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
HUE67_RS09650	COG0009	L-threonylcarbamoyladenylate synthase
HUE67_RS09705	COG1070	Carbohydrate kinase
HUE67_RS09720	COG4214	carbohydrate transport
HUE67_RS09725	COG1129	ABC transporter
HUE67_RS09730	COG4213	ABC transporter substrate-binding protein
HUE67_RS09745	COG0110	maltose O-acetyltransferase activity
HUE67_RS09750	COG3507	Belongs to the glycosyl hydrolase 43 family
HUE67_RS09755	COG3507	Belongs to the glycosyl hydrolase 43 family
HUE67_RS09760	COG0395	ABC-type sugar transport system, permease component
HUE67_RS09775	COG1609	Transcriptional regulator
HUE67_RS09780	COG1979	alcohol dehydrogenase
HUE67_RS09790	COG2814	Major facilitator Superfamily
HUE67_RS09795	COG2814	Major facilitator Superfamily
HUE67_RS09805	COG0242	peptide deformylase activity
HUE67_RS09820	COG1940	carbohydrate kinase activity
HUE67_RS09840	COG0577	efflux transmembrane transporter activity
HUE67_RS09840	COG1136	(ABC) transporter
HUE67_RS09845	COG1136	(ABC) transporter
HUE67_RS09845	COG4591	ABC-type transport system involved in lipoprotein release permease component
HUE67_RS09890	COG1946	Acyl-CoA thioesterase
HUE67_RS09900	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
HUE67_RS09905	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
HUE67_RS09915	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
HUE67_RS09920	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
HUE67_RS09960	COG1454	alcohol dehydrogenase
HUE67_RS09965	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
HUE67_RS09980	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
HUE67_RS10015	COG1192	Involved in chromosome partitioning
HUE67_RS10055	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
HUE67_RS10100	COG1131	(ABC) transporter
HUE67_RS10205	COG4585	Histidine kinase
HUE67_RS10210	COG2197	response regulator
HUE67_RS10220	COG1505	serine-type exopeptidase activity
HUE67_RS10245	COG4585	Histidine kinase
HUE67_RS10285	COG1131	(ABC) transporter
HUE67_RS10295	COG1132	(ABC) transporter
HUE67_RS10300	COG1136	(ABC) transporter
HUE67_RS10300	COG0577	efflux transmembrane transporter activity
HUE67_RS10310	COG4585	Histidine kinase
HUE67_RS10335	COG4974	Belongs to the 'phage' integrase family
HUE67_RS10375	COG0577	efflux transmembrane transporter activity
HUE67_RS10380	COG1136	(ABC) transporter
HUE67_RS10385	COG5002	protein histidine kinase activity
HUE67_RS10440	COG0577	efflux transmembrane transporter activity
HUE67_RS10520	COG2814	Major facilitator Superfamily
HUE67_RS10570	COG1136	(ABC) transporter
HUE67_RS10595	COG2814	Major facilitator Superfamily
HUE67_RS10630	COG1609	Transcriptional regulator
HUE67_RS10635	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
HUE67_RS10655	COG1116	anion transmembrane transporter activity
HUE67_RS10685	COG2348	transferase activity, transferring amino-acyl groups
HUE67_RS10730	COG0667	Aldo Keto reductase
HUE67_RS10770	COG0440	acetolactate synthase activity
HUE67_RS10780	COG1487	ribonuclease activity
HUE67_RS10800	COG0505	Belongs to the CarA family
HUE67_RS10830	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE67_RS10830	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
HUE67_RS10860	COG1837	Belongs to the UPF0109 family
HUE67_RS10885	COG1957	nucleoside hydrolase
HUE67_RS10910	COG1704	LemA family
HUE67_RS10935	COG0745	RESPONSE REGULATOR receiver
HUE67_RS10940	COG5002	protein histidine kinase activity
HUE67_RS10945	COG0477	Major facilitator Superfamily
HUE67_RS10950	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
HUE67_RS10955	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUE67_RS10960	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
HUE67_RS10965	COG3579	cysteine-type endopeptidase activity
HUE67_RS10975	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
HUE67_RS10985	COG1496	oxidoreductase activity
HUE67_RS10990	COG0826	peptidase U32
HUE67_RS11000	COG0742	ribosomal rna small subunit methyltransferase
HUE67_RS11005	COG1301	dicarboxylic acid transport
HUE67_RS11035	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
HUE67_RS11035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
HUE67_RS11040	COG2270	Major facilitator Superfamily
HUE67_RS11090	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
HUE67_RS11105	COG1027	Aspartate ammonia-lyase
HUE67_RS11120	COG3842	ATPase activity
HUE67_RS11155	COG0251	oxidation-reduction process
HUE67_RS11205	COG0545	Peptidyl-prolyl cis-trans isomerase
HUE67_RS11215	COG0355	proton-transporting ATP synthase activity, rotational mechanism
HUE67_RS11250	COG0356	it plays a direct role in the translocation of protons across the membrane
HUE67_RS11325	COG0582	viral genome integration into host DNA
HUE67_RS11375	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
HUE67_RS11390	COG0745	RESPONSE REGULATOR receiver
HUE67_RS11475	COG1322	Protein conserved in bacteria
HUE67_RS11480	COG1937	Protein conserved in bacteria
HUE67_RS11490	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family