locus-tag	class	description
BLNIAS_RS00005	COG2826	transposase and inactivated derivatives, IS30 family
BLNIAS_RS00030	COG0588	phosphoglycerate mutase activity
BLNIAS_RS00040	COG1609	Transcriptional regulator
BLNIAS_RS00075	COG1113	amino acid transport
BLNIAS_RS00085	COG1136	(ABC) transporter
BLNIAS_RS00085	COG0577	efflux transmembrane transporter activity
BLNIAS_RS00095	COG1113	amino acid transport
BLNIAS_RS00115	COG3645	SOS response
BLNIAS_RS00130	COG1132	(ABC) transporter
BLNIAS_RS00195	COG1609	Transcriptional regulator
BLNIAS_RS00205	COG1132	(ABC) transporter
BLNIAS_RS00210	COG1132	(ABC) transporter
BLNIAS_RS00220	COG0084	hydrolase, TatD family'
BLNIAS_RS00240	COG1129	ABC transporter
BLNIAS_RS00290	COG1216	Glycosyl transferase, family 2
BLNIAS_RS00315	COG1088	dTDP-glucose 4,6-dehydratase activity
BLNIAS_RS00350	COG0179	Fumarylacetoacetate (FAA) hydrolase
BLNIAS_RS00360	COG2986	histidine ammonia-lyase
BLNIAS_RS00375	COG0584	glycerophosphoryl diester phosphodiesterase
BLNIAS_RS00390	COG2801	Transposase and inactivated derivatives
BLNIAS_RS00405	COG0494	nUDIX hydrolase
BLNIAS_RS00405	COG0406	alpha-ribazole phosphatase activity
BLNIAS_RS00410	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BLNIAS_RS00435	COG0167	dihydroorotate dehydrogenase activity
BLNIAS_RS00440	COG0446	pyridine nucleotide-disulphide oxidoreductase
BLNIAS_RS00445	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLNIAS_RS00465	COG1309	transcriptional regulator
BLNIAS_RS00480	COG0460	homoserine dehydrogenase
BLNIAS_RS00485	COG0083	homoserine kinase activity
BLNIAS_RS00515	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLNIAS_RS00520	COG1530	ribonuclease E activity
BLNIAS_RS00545	COG0436	Aminotransferase
BLNIAS_RS00555	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLNIAS_RS00560	COG0250	Participates in transcription elongation, termination and antitermination
BLNIAS_RS00615	COG1268	BioY protein
BLNIAS_RS00620	COG4770	biotin carboxylase activity
BLNIAS_RS00625	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLNIAS_RS00655	COG3507	Belongs to the glycosyl hydrolase 43 family
BLNIAS_RS00660	COG3507	Belongs to the glycosyl hydrolase 43 family
BLNIAS_RS00670	COG2826	transposase and inactivated derivatives, IS30 family
BLNIAS_RS00680	COG1122	ATPase activity
BLNIAS_RS00685	COG1132	(ABC) transporter
BLNIAS_RS00700	COG2252	PERMEase
BLNIAS_RS00790	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BLNIAS_RS00795	COG0531	amino acid
BLNIAS_RS00810	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLNIAS_RS00830	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLNIAS_RS00835	COG1739	Uncharacterized protein family UPF0029
BLNIAS_RS00865	COG1063	alcohol dehydrogenase
BLNIAS_RS00885	COG1063	alcohol dehydrogenase
BLNIAS_RS00900	COG1454	alcohol dehydrogenase
BLNIAS_RS00900	COG1012	belongs to the aldehyde dehydrogenase family
BLNIAS_RS00955	COG0255	Belongs to the universal ribosomal protein uL29 family
BLNIAS_RS01060	COG2308	Evidence 4 Homologs of previously reported genes of
BLNIAS_RS01075	COG3534	alpha-L-arabinofuranosidase
BLNIAS_RS01110	COG0196	riboflavin kinase activity
BLNIAS_RS01130	COG0328	RNA-DNA hybrid ribonuclease activity
BLNIAS_RS01140	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLNIAS_RS01170	COG3711	transcriptional antiterminator
BLNIAS_RS01175	COG1803	Methylglyoxal synthase
BLNIAS_RS01175	COG1597	lipid kinase activity
BLNIAS_RS01195	COG1175	transmembrane transport
BLNIAS_RS01200	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS01225	COG2197	response regulator
BLNIAS_RS01260	COG2814	Major facilitator Superfamily
BLNIAS_RS01270	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BLNIAS_RS01275	COG1575	Belongs to the MenA family. Type 1 subfamily
BLNIAS_RS01285	COG0704	Plays a role in the regulation of phosphate uptake
BLNIAS_RS01290	COG5002	protein histidine kinase activity
BLNIAS_RS01300	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BLNIAS_RS01305	COG1705	Flagellar rod assembly protein muramidase FlgJ
BLNIAS_RS01305	COG3942	CHAP domain
BLNIAS_RS01315	COG0791	NLP P60 protein
BLNIAS_RS01320	COG0589	response to stress
BLNIAS_RS01340	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLNIAS_RS01345	COG1687	branched-chain amino acid
BLNIAS_RS01350	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
BLNIAS_RS01400	COG1705	Flagellar rod assembly protein muramidase FlgJ
BLNIAS_RS01400	COG3942	CHAP domain
BLNIAS_RS01435	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BLNIAS_RS01455	COG1192	Involved in chromosome partitioning
BLNIAS_RS01485	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BLNIAS_RS01500	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BLNIAS_RS01505	COG1454	alcohol dehydrogenase
BLNIAS_RS01545	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BLNIAS_RS01550	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLNIAS_RS01560	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BLNIAS_RS01565	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
BLNIAS_RS01575	COG1946	Acyl-CoA thioesterase
BLNIAS_RS01590	COG1940	carbohydrate kinase activity
BLNIAS_RS01595	COG1129	ABC transporter
BLNIAS_RS01615	COG4214	carbohydrate transport
BLNIAS_RS01630	COG2814	Major facilitator Superfamily
BLNIAS_RS01645	COG0242	peptide deformylase activity
BLNIAS_RS01655	COG2814	Major facilitator Superfamily
BLNIAS_RS01660	COG2814	Major facilitator Superfamily
BLNIAS_RS01670	COG1979	alcohol dehydrogenase
BLNIAS_RS01675	COG1609	Transcriptional regulator
BLNIAS_RS01685	COG1175	transmembrane transport
BLNIAS_RS01690	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS01695	COG3507	Belongs to the glycosyl hydrolase 43 family
BLNIAS_RS01700	COG3507	Belongs to the glycosyl hydrolase 43 family
BLNIAS_RS01730	COG1070	Carbohydrate kinase
BLNIAS_RS01785	COG0110	maltose O-acetyltransferase activity
BLNIAS_RS01790	COG0009	L-threonylcarbamoyladenylate synthase
BLNIAS_RS01795	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLNIAS_RS01810	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLNIAS_RS01845	COG3590	peptidase
BLNIAS_RS01910	COG0436	Aminotransferase
BLNIAS_RS01915	COG0248	Ppx GppA phosphatase
BLNIAS_RS01940	COG1970	mechanosensitive ion channel activity
BLNIAS_RS01945	COG1022	Amp-dependent synthetase and ligase
BLNIAS_RS01950	COG2249	NAD(P)H dehydrogenase (quinone) activity
BLNIAS_RS01955	COG1722	exodeoxyribonuclease VII activity
BLNIAS_RS01960	COG1570	exodeoxyribonuclease VII activity
BLNIAS_RS01965	COG1328	CTP reductase activity
BLNIAS_RS01965	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLNIAS_RS01970	COG0602	queuosine metabolic process
BLNIAS_RS01985	COG1309	transcriptional regulator
BLNIAS_RS02010	COG3293	Transposase
BLNIAS_RS02020	COG2182	Extracellular solute-binding protein
BLNIAS_RS02030	COG0154	amidase activity
BLNIAS_RS02040	COG1609	Transcriptional regulator
BLNIAS_RS02105	COG1472	Belongs to the glycosyl hydrolase 3 family
BLNIAS_RS02115	COG1132	(ABC) transporter
BLNIAS_RS02120	COG1132	(ABC) transporter
BLNIAS_RS02140	COG3069	C4-dicarboxylate transmembrane transporter activity
BLNIAS_RS02145	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLNIAS_RS02155	COG1609	Transcriptional regulator
BLNIAS_RS02160	COG3250	beta-galactosidase activity
BLNIAS_RS02165	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
BLNIAS_RS02190	COG1715	Restriction endonuclease
BLNIAS_RS02210	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
BLNIAS_RS02245	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BLNIAS_RS02250	COG0560	Phosphoserine phosphatase
BLNIAS_RS02255	COG0586	Pfam SNARE associated Golgi protein
BLNIAS_RS02285	COG3279	Response regulator of the LytR AlgR family
BLNIAS_RS02295	COG1472	Belongs to the glycosyl hydrolase 3 family
BLNIAS_RS02310	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLNIAS_RS02365	COG0714	Associated with various cellular activities
BLNIAS_RS02380	COG1278	Cold shock
BLNIAS_RS02400	COG0745	RESPONSE REGULATOR receiver
BLNIAS_RS02405	COG2205	protein histidine kinase activity
BLNIAS_RS02410	COG1278	Cold shock
BLNIAS_RS02420	COG0589	response to stress
BLNIAS_RS02430	COG0402	S-adenosylhomocysteine deaminase activity
BLNIAS_RS02440	COG0477	Major facilitator Superfamily
BLNIAS_RS02455	COG1196	nuclear chromosome segregation
BLNIAS_RS02475	COG1126	abc transporter atp-binding protein
BLNIAS_RS02480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLNIAS_RS02485	COG0765	amino acid transport
BLNIAS_RS02490	COG0765	amino acid transport
BLNIAS_RS02515	COG2326	polyphosphate kinase activity
BLNIAS_RS02520	COG4581	dead DEAH box helicase
BLNIAS_RS02530	COG0745	RESPONSE REGULATOR receiver
BLNIAS_RS02565	COG2814	Major facilitator Superfamily
BLNIAS_RS02570	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLNIAS_RS02625	COG1122	ATPase activity
BLNIAS_RS02665	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS02680	COG1501	Belongs to the glycosyl hydrolase 31 family
BLNIAS_RS02685	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLNIAS_RS02700	COG4106	trans-aconitate 2-methyltransferase activity
BLNIAS_RS02710	COG1376	ErfK ybiS ycfS ynhG family protein
BLNIAS_RS02715	COG0390	transport system, permease component
BLNIAS_RS02720	COG0577	efflux transmembrane transporter activity
BLNIAS_RS02720	COG1136	(ABC) transporter
BLNIAS_RS02745	COG0284	orotidine-5'-phosphate decarboxylase activity
BLNIAS_RS02760	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BLNIAS_RS02775	COG0765	amino acid transport
BLNIAS_RS02780	COG1126	abc transporter atp-binding protein
BLNIAS_RS02785	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLNIAS_RS02790	COG0626	cystathionine gamma-synthase activity
BLNIAS_RS02815	COG2873	o-acetylhomoserine
BLNIAS_RS02835	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BLNIAS_RS02870	COG3480	Lon protease (S16) C-terminal proteolytic domain
BLNIAS_RS02915	COG1957	nucleoside hydrolase
BLNIAS_RS02925	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLNIAS_RS02955	COG2271	Major facilitator Superfamily
BLNIAS_RS02965	COG0352	thiamine-phosphate diphosphorylase activity
BLNIAS_RS02965	COG0351	phosphomethylpyrimidine kinase
BLNIAS_RS02995	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLNIAS_RS03025	COG1373	ATPase (AAA superfamily
BLNIAS_RS03045	COG3857	The heterodimer acts as both an ATP-dependent DNA helicase and an ATP-dependent, dual-direction single-stranded exonuclease. Recognizes the chi site generating a DNA molecule suitable for the initiation of homologous recombination
BLNIAS_RS03050	COG1074	ATP-dependent DNA helicase activity
BLNIAS_RS03065	COG1484	DNA-dependent DNA replication
BLNIAS_RS03095	COG4974	Belongs to the 'phage' integrase family
BLNIAS_RS03140	COG0587	DNA-directed DNA polymerase activity
BLNIAS_RS03150	COG4716	Myosin-crossreactive antigen
BLNIAS_RS03175	COG0656	L-ascorbic acid biosynthetic process
BLNIAS_RS03225	COG0174	glutamine synthetase
BLNIAS_RS03240	COG1643	Atp-dependent helicase
BLNIAS_RS03245	COG2813	Specifically methylates the guanine in position
BLNIAS_RS03250	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BLNIAS_RS03280	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLNIAS_RS03305	COG0768	penicillin binding
BLNIAS_RS03315	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLNIAS_RS03350	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BLNIAS_RS03365	COG0738	Major facilitator superfamily
BLNIAS_RS03385	COG1940	carbohydrate kinase activity
BLNIAS_RS03405	COG4166	transmembrane transport
BLNIAS_RS03410	COG0601	transmembrane transport
BLNIAS_RS03430	COG0006	proline dipeptidase activity
BLNIAS_RS03440	COG0285	dihydrofolate synthase activity
BLNIAS_RS03445	COG1196	nuclear chromosome segregation
BLNIAS_RS03460	COG1595	DNA-templated transcription, initiation
BLNIAS_RS03470	COG2017	converts alpha-aldose to the beta-anomer
BLNIAS_RS03475	COG2017	converts alpha-aldose to the beta-anomer
BLNIAS_RS03485	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BLNIAS_RS03505	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLNIAS_RS03525	COG0577	efflux transmembrane transporter activity
BLNIAS_RS03525	COG1136	(ABC) transporter
BLNIAS_RS03535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BLNIAS_RS03540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BLNIAS_RS03550	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BLNIAS_RS03555	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BLNIAS_RS03565	COG1104	cysteine desulfurase activity
BLNIAS_RS03570	COG0477	Major facilitator Superfamily
BLNIAS_RS03575	COG1217	gtp-binding protein TYPA
BLNIAS_RS03585	COG0077	Prephenate dehydratase
BLNIAS_RS03585	COG1605	Chorismate mutase
BLNIAS_RS03590	COG0287	Prephenate dehydrogenase
BLNIAS_RS03605	COG4166	transmembrane transport
BLNIAS_RS03610	COG0601	transmembrane transport
BLNIAS_RS03615	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLNIAS_RS03625	COG0708	Exodeoxyribonuclease III
BLNIAS_RS03680	COG2197	response regulator
BLNIAS_RS03695	COG0670	Belongs to the BI1 family
BLNIAS_RS03705	COG2357	RelA SpoT domain protein
BLNIAS_RS03735	COG1546	Belongs to the CinA family
BLNIAS_RS03735	COG1058	Belongs to the CinA family
BLNIAS_RS03740	COG1396	sequence-specific DNA binding
BLNIAS_RS03760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLNIAS_RS03780	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLNIAS_RS03800	COG0142	geranyltranstransferase activity
BLNIAS_RS03810	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLNIAS_RS03815	COG0187	DNA topoisomerase II activity
BLNIAS_RS03825	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLNIAS_RS03830	COG1201	RNA secondary structure unwinding
BLNIAS_RS03840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLNIAS_RS03865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BLNIAS_RS03870	COG2801	Transposase and inactivated derivatives
BLNIAS_RS03890	COG3328	transposase activity
BLNIAS_RS03895	COG3328	transposase activity
BLNIAS_RS03915	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BLNIAS_RS03955	COG0305	Participates in initiation and elongation during chromosome replication
BLNIAS_RS03980	COG0406	alpha-ribazole phosphatase activity
BLNIAS_RS03985	COG0598	Magnesium transport protein CorA
BLNIAS_RS03990	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLNIAS_RS04000	COG1555	photosystem II stabilization
BLNIAS_RS04000	COG1596	polysaccharide export
BLNIAS_RS04010	COG1228	amidohydrolase
BLNIAS_RS04020	COG0802	atpase or kinase
BLNIAS_RS04030	COG0456	acetyltransferase
BLNIAS_RS04090	COG3942	CHAP domain
BLNIAS_RS04110	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLNIAS_RS04110	COG0551	DNA topoisomerase type I activity
BLNIAS_RS04260	COG1192	Involved in chromosome partitioning
BLNIAS_RS04320	COG0516	GMP reductase activity
BLNIAS_RS04360	COG0575	Belongs to the CDS family
BLNIAS_RS04370	COG0693	protein deglycase activity
BLNIAS_RS04395	COG0488	(ABC) transporter
BLNIAS_RS04400	COG4221	oxidoreductase activity
BLNIAS_RS04415	COG1129	ABC transporter
BLNIAS_RS04465	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BLNIAS_RS04490	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLNIAS_RS04505	COG0436	Aminotransferase
BLNIAS_RS04520	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BLNIAS_RS04620	COG0045	succinate-CoA ligase (ADP-forming) activity
BLNIAS_RS04640	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLNIAS_RS04645	COG1187	pseudouridine synthase activity
BLNIAS_RS04720	COG0513	Belongs to the DEAD box helicase family
BLNIAS_RS04785	COG1803	Methylglyoxal synthase
BLNIAS_RS04800	COG1716	ATPase activity
BLNIAS_RS04820	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLNIAS_RS04835	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BLNIAS_RS04850	COG0133	tryptophan synthase activity
BLNIAS_RS04880	COG2826	transposase and inactivated derivatives, IS30 family
BLNIAS_RS04925	COG1131	(ABC) transporter
BLNIAS_RS04930	COG0745	RESPONSE REGULATOR receiver
BLNIAS_RS04955	COG1131	(ABC) transporter
BLNIAS_RS04960	COG2826	transposase and inactivated derivatives, IS30 family
BLNIAS_RS04965	COG2197	response regulator
BLNIAS_RS04970	COG4585	Histidine kinase
BLNIAS_RS04980	COG1136	(ABC) transporter
BLNIAS_RS04980	COG0577	efflux transmembrane transporter activity
BLNIAS_RS05020	COG1051	belongs to the nudix hydrolase family
BLNIAS_RS05025	COG0706	membrane insertase activity
BLNIAS_RS05030	COG0706	membrane insertase activity
BLNIAS_RS05045	COG0833	amino acid
BLNIAS_RS05050	COG0681	Belongs to the peptidase S26 family
BLNIAS_RS05085	COG0583	DNA-binding transcription factor activity
BLNIAS_RS05100	COG0167	dihydroorotate dehydrogenase activity
BLNIAS_RS05105	COG0543	2 iron, 2 sulfur cluster binding
BLNIAS_RS05110	COG0284	orotidine-5'-phosphate decarboxylase activity
BLNIAS_RS05115	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLNIAS_RS05140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BLNIAS_RS05150	COG0588	phosphoglycerate mutase activity
BLNIAS_RS05175	COG4989	oxidoreductase activity
BLNIAS_RS05240	COG1397	ADP-ribosylglycohydrolase
BLNIAS_RS05260	COG0561	phosphatase activity
BLNIAS_RS05265	COG1119	ATPase activity
BLNIAS_RS05270	COG0297	glycogen (starch) synthase activity
BLNIAS_RS05285	COG4166	transmembrane transport
BLNIAS_RS05305	COG0070	glutamate synthase
BLNIAS_RS05305	COG0069	glutamate synthase activity
BLNIAS_RS05305	COG0067	glutamate synthase
BLNIAS_RS05310	COG1609	Transcriptional regulator
BLNIAS_RS05315	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BLNIAS_RS05330	COG1609	Transcriptional regulator
BLNIAS_RS05345	COG1929	Belongs to the glycerate kinase type-1 family
BLNIAS_RS05370	COG2860	membrane
BLNIAS_RS05380	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BLNIAS_RS05405	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BLNIAS_RS05430	COG1702	phosphate starvation-inducible protein PhoH
BLNIAS_RS05435	COG0537	adenosine 5'-monophosphoramidase activity
BLNIAS_RS05440	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BLNIAS_RS05460	COG2151	metal-sulfur cluster biosynthetic enzyme
BLNIAS_RS05470	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLNIAS_RS05475	COG0396	ATPase activity
BLNIAS_RS05480	COG0719	Fe-S assembly protein
BLNIAS_RS05510	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BLNIAS_RS05555	COG0588	phosphoglycerate mutase activity
BLNIAS_RS05560	COG2755	lipolytic protein G-D-S-L family
BLNIAS_RS05560	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BLNIAS_RS05570	COG1136	(ABC) transporter
BLNIAS_RS05570	COG0577	efflux transmembrane transporter activity
BLNIAS_RS05600	COG3655	Transcriptional regulator
BLNIAS_RS05645	COG1131	(ABC) transporter
BLNIAS_RS05650	COG4585	Histidine kinase
BLNIAS_RS05655	COG2197	response regulator
BLNIAS_RS05665	COG0306	phosphate transporter
BLNIAS_RS05675	COG1966	Carbon starvation protein
BLNIAS_RS05685	COG1309	transcriptional regulator
BLNIAS_RS05690	COG0513	Belongs to the DEAD box helicase family
BLNIAS_RS05695	COG2233	PERMEase
BLNIAS_RS05740	COG0515	serine threonine protein kinase
BLNIAS_RS05740	COG2815	serine threonine protein kinase
BLNIAS_RS05750	COG2814	Major facilitator Superfamily
BLNIAS_RS05795	COG4974	Belongs to the 'phage' integrase family
BLNIAS_RS05800	COG0012	GTP binding
BLNIAS_RS05805	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BLNIAS_RS05820	COG2197	response regulator
BLNIAS_RS05825	COG0577	efflux transmembrane transporter activity
BLNIAS_RS05825	COG1136	(ABC) transporter
BLNIAS_RS05830	COG1136	(ABC) transporter
BLNIAS_RS05835	COG2873	o-acetylhomoserine
BLNIAS_RS05855	COG0758	DNA mediated transformation
BLNIAS_RS05860	COG1053	succinate dehydrogenase
BLNIAS_RS05875	COG1611	Belongs to the LOG family
BLNIAS_RS05935	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BLNIAS_RS05940	COG1882	Formate acetyltransferase
BLNIAS_RS05955	COG1473	amidohydrolase
BLNIAS_RS05960	COG2011	ABC-type metal ion transport system permease component
BLNIAS_RS06030	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BLNIAS_RS06030	COG2755	lipolytic protein G-D-S-L family
BLNIAS_RS06050	COG0799	negative regulation of ribosome biogenesis
BLNIAS_RS06055	COG0406	alpha-ribazole phosphatase activity
BLNIAS_RS06070	COG0857	belongs to the CobB CobQ family
BLNIAS_RS06070	COG0280	phosphate acetyltransferase
BLNIAS_RS06075	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLNIAS_RS06110	COG3250	beta-galactosidase activity
BLNIAS_RS06120	COG0519	Catalyzes the synthesis of GMP from XMP
BLNIAS_RS06145	COG1051	belongs to the nudix hydrolase family
BLNIAS_RS06150	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BLNIAS_RS06170	COG0494	nUDIX hydrolase
BLNIAS_RS06175	COG0469	pyruvate kinase activity
BLNIAS_RS06195	COG0539	negative regulation of cytoplasmic translation
BLNIAS_RS06205	COG0803	Belongs to the bacterial solute-binding protein 9 family
BLNIAS_RS06210	COG1121	(ABC) transporter
BLNIAS_RS06225	COG1329	Transcriptional regulator
BLNIAS_RS06235	COG0745	RESPONSE REGULATOR receiver
BLNIAS_RS06240	COG2205	protein histidine kinase activity
BLNIAS_RS06250	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLNIAS_RS06285	COG1316	TRANSCRIPTIONal
BLNIAS_RS06315	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLNIAS_RS06325	COG1760	l-serine dehydratase
BLNIAS_RS06360	COG0667	Aldo Keto reductase
BLNIAS_RS06375	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLNIAS_RS06375	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLNIAS_RS06390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLNIAS_RS06420	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BLNIAS_RS06445	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLNIAS_RS06450	COG0497	DNA recombination
BLNIAS_RS06460	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLNIAS_RS06465	COG0569	domain protein
BLNIAS_RS06505	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
BLNIAS_RS06510	COG0476	Involved in molybdopterin and thiamine biosynthesis, family 2
BLNIAS_RS06580	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLNIAS_RS06590	COG1122	ATPase activity
BLNIAS_RS06595	COG4721	ABC-type cobalt transport system, permease component
BLNIAS_RS06600	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLNIAS_RS06625	COG3250	beta-galactosidase activity
BLNIAS_RS06645	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BLNIAS_RS06690	COG1063	alcohol dehydrogenase
BLNIAS_RS06715	COG0583	DNA-binding transcription factor activity
BLNIAS_RS06745	COG0385	Bile acid
BLNIAS_RS06775	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLNIAS_RS06805	COG0667	Aldo Keto reductase
BLNIAS_RS06815	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLNIAS_RS06820	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BLNIAS_RS06825	COG0402	S-adenosylhomocysteine deaminase activity
BLNIAS_RS06835	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLNIAS_RS06865	COG1012	belongs to the aldehyde dehydrogenase family
BLNIAS_RS06890	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BLNIAS_RS06895	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BLNIAS_RS06905	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BLNIAS_RS06910	COG1136	(ABC) transporter
BLNIAS_RS06910	COG0577	efflux transmembrane transporter activity
BLNIAS_RS06920	COG1136	(ABC) transporter
BLNIAS_RS06920	COG0577	efflux transmembrane transporter activity
BLNIAS_RS06935	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BLNIAS_RS06950	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BLNIAS_RS06960	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BLNIAS_RS06975	COG3655	Transcriptional regulator
BLNIAS_RS06985	COG0358	DNA primase activity
BLNIAS_RS06995	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLNIAS_RS07000	COG0531	amino acid
BLNIAS_RS07005	COG2826	transposase and inactivated derivatives, IS30 family
BLNIAS_RS07025	COG0514	ATP-dependent DNA helicase (RecQ)
BLNIAS_RS07035	COG0626	cystathionine gamma-synthase activity
BLNIAS_RS07045	COG4608	Belongs to the ABC transporter superfamily
BLNIAS_RS07055	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BLNIAS_RS07060	COG0601	transmembrane transport
BLNIAS_RS07065	COG0747	negative chemotaxis
BLNIAS_RS07080	COG1653	transport
BLNIAS_RS07085	COG1653	transport
BLNIAS_RS07090	COG3534	alpha-L-arabinofuranosidase
BLNIAS_RS07095	COG1609	Transcriptional regulator
BLNIAS_RS07105	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS07110	COG1175	transmembrane transport
BLNIAS_RS07125	COG3550	peptidyl-serine autophosphorylation
BLNIAS_RS07130	COG0564	pseudouridine synthase activity
BLNIAS_RS07170	COG2177	Part of the ABC transporter FtsEX involved in
BLNIAS_RS07175	COG2884	Cell division ATP-binding protein ftsE
BLNIAS_RS07180	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BLNIAS_RS07220	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BLNIAS_RS07240	COG0210	DNA helicase
BLNIAS_RS07260	COG0714	Associated with various cellular activities
BLNIAS_RS07305	COG1194	a g-specific adenine glycosylase
BLNIAS_RS07310	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BLNIAS_RS07325	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BLNIAS_RS07335	COG1349	DNA-binding transcription factor activity
BLNIAS_RS07340	COG0167	dihydroorotate dehydrogenase activity
BLNIAS_RS07345	COG1902	pentaerythritol trinitrate reductase activity
BLNIAS_RS07350	COG4499	WXG100 protein secretion system (Wss), protein YukC
BLNIAS_RS07350	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLNIAS_RS07360	COG0095	Lipoate-protein ligase
BLNIAS_RS07400	COG3118	belongs to the thioredoxin family
BLNIAS_RS07400	COG0492	ferredoxin-NADP+ reductase activity
BLNIAS_RS07415	COG0489	protein tyrosine kinase activity
BLNIAS_RS07470	COG2801	Transposase and inactivated derivatives
BLNIAS_RS07555	COG1216	Glycosyl transferase, family 2
BLNIAS_RS07555	COG1442	glycosyl transferase family 8
BLNIAS_RS07565	COG0438	transferase activity, transferring glycosyl groups
BLNIAS_RS07580	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLNIAS_RS07595	COG2814	Major facilitator Superfamily
BLNIAS_RS07600	COG2801	Transposase and inactivated derivatives
BLNIAS_RS07620	COG0656	L-ascorbic acid biosynthetic process
BLNIAS_RS07650	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS07655	COG1175	transmembrane transport
BLNIAS_RS07660	COG1653	transport
BLNIAS_RS07665	COG2814	Major facilitator Superfamily
BLNIAS_RS07670	COG4988	ABC transporter
BLNIAS_RS07675	COG2814	Major facilitator Superfamily
BLNIAS_RS07695	COG0577	efflux transmembrane transporter activity
BLNIAS_RS07705	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BLNIAS_RS07725	COG1609	Transcriptional regulator
BLNIAS_RS07730	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLNIAS_RS07770	COG2348	transferase activity, transferring amino-acyl groups
BLNIAS_RS07800	COG2826	transposase and inactivated derivatives, IS30 family
BLNIAS_RS07820	COG0667	Aldo Keto reductase
BLNIAS_RS07860	COG0440	acetolactate synthase activity
BLNIAS_RS07875	COG0488	(ABC) transporter
BLNIAS_RS07880	COG0505	Belongs to the CarA family
BLNIAS_RS07910	COG1837	Belongs to the UPF0109 family
BLNIAS_RS07920	COG1957	nucleoside hydrolase
BLNIAS_RS07935	COG1704	LemA family
BLNIAS_RS07960	COG0745	RESPONSE REGULATOR receiver
BLNIAS_RS07965	COG5002	protein histidine kinase activity
BLNIAS_RS07970	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BLNIAS_RS07975	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BLNIAS_RS07980	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BLNIAS_RS07985	COG3579	cysteine-type endopeptidase activity
BLNIAS_RS07995	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BLNIAS_RS08005	COG1496	oxidoreductase activity
BLNIAS_RS08010	COG0826	peptidase U32
BLNIAS_RS08020	COG0742	ribosomal rna small subunit methyltransferase
BLNIAS_RS08035	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BLNIAS_RS08035	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BLNIAS_RS08040	COG2270	Major facilitator Superfamily
BLNIAS_RS08065	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BLNIAS_RS08080	COG1027	Aspartate ammonia-lyase
BLNIAS_RS08095	COG3842	ATPase activity
BLNIAS_RS08130	COG0251	oxidation-reduction process
BLNIAS_RS08160	COG2801	Transposase and inactivated derivatives
BLNIAS_RS08165	COG0545	Peptidyl-prolyl cis-trans isomerase
BLNIAS_RS08175	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BLNIAS_RS08210	COG0356	it plays a direct role in the translocation of protons across the membrane
BLNIAS_RS08240	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BLNIAS_RS08255	COG0745	RESPONSE REGULATOR receiver
BLNIAS_RS08280	COG1605	Chorismate mutase
BLNIAS_RS08280	COG0287	Prephenate dehydrogenase
BLNIAS_RS08330	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLNIAS_RS08340	COG1322	Protein conserved in bacteria
BLNIAS_RS08345	COG1937	Protein conserved in bacteria
BLNIAS_RS08355	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BLNIAS_RS08360	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BLNIAS_RS08365	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLNIAS_RS08405	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BLNIAS_RS08425	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS08430	COG1175	transmembrane transport
BLNIAS_RS08440	COG1609	Transcriptional regulator
BLNIAS_RS08460	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLNIAS_RS08465	COG0305	Participates in initiation and elongation during chromosome replication
BLNIAS_RS08475	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BLNIAS_RS08495	COG1309	transcriptional regulator
BLNIAS_RS08500	COG1215	transferase activity, transferring glycosyl groups
BLNIAS_RS08525	COG0363	glucosamine-6-phosphate deaminase activity
BLNIAS_RS08530	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BLNIAS_RS08560	COG1136	(ABC) transporter
BLNIAS_RS08565	COG0577	efflux transmembrane transporter activity
BLNIAS_RS08580	COG3470	protein probably involved in high-affinity Fe2 transport
BLNIAS_RS08585	COG0672	)-iron permease
BLNIAS_RS08600	COG3619	membrane
BLNIAS_RS08605	COG0366	Alpha amylase catalytic
BLNIAS_RS08645	COG0732	type I restriction modification DNA specificity domain
BLNIAS_RS08660	COG3152	Membrane
BLNIAS_RS08725	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLNIAS_RS08725	COG1754	DNA topoisomerase type I activity
BLNIAS_RS08740	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BLNIAS_RS08765	COG0527	aspartate kinase activity
BLNIAS_RS08840	COG0586	Pfam SNARE associated Golgi protein
BLNIAS_RS08845	COG1609	Transcriptional regulator
BLNIAS_RS08860	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS08865	COG1175	transmembrane transport
BLNIAS_RS08870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLNIAS_RS08875	COG1028	Short-chain dehydrogenase reductase Sdr
BLNIAS_RS08895	COG0789	Transcriptional regulator
BLNIAS_RS08920	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS08925	COG1609	Transcriptional regulator
BLNIAS_RS08950	COG0366	Alpha amylase catalytic
BLNIAS_RS08965	COG0477	Major facilitator Superfamily
BLNIAS_RS09000	COG4974	Belongs to the 'phage' integrase family
BLNIAS_RS09020	COG3534	alpha-L-arabinofuranosidase
BLNIAS_RS09095	COG0343	queuine tRNA-ribosyltransferase activity
BLNIAS_RS09130	COG0494	nUDIX hydrolase
BLNIAS_RS09145	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BLNIAS_RS09165	COG0071	Belongs to the small heat shock protein (HSP20) family
BLNIAS_RS09220	COG0768	penicillin binding
BLNIAS_RS09225	COG0515	serine threonine protein kinase
BLNIAS_RS09265	COG0058	SHG alpha-glucan phosphorylase activity
BLNIAS_RS09280	COG0180	Tryptophanyl-tRNA synthetase
BLNIAS_RS09295	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLNIAS_RS09305	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BLNIAS_RS09355	COG1253	flavin adenine dinucleotide binding
BLNIAS_RS09360	COG0783	Belongs to the Dps family
BLNIAS_RS09370	COG3265	gluconokinase activity
BLNIAS_RS09380	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLNIAS_RS09385	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BLNIAS_RS09430	COG0436	Aminotransferase
BLNIAS_RS09435	COG1522	sequence-specific DNA binding
BLNIAS_RS09440	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BLNIAS_RS09445	COG4677	pectinesterase activity
BLNIAS_RS09455	COG2826	transposase and inactivated derivatives, IS30 family
BLNIAS_RS09460	COG3266	domain, Protein
BLNIAS_RS09465	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLNIAS_RS09470	COG0187	DNA topoisomerase II activity
BLNIAS_RS09485	COG0592	DNA-directed DNA polymerase activity
BLNIAS_RS09525	COG1192	Involved in chromosome partitioning
BLNIAS_RS09530	COG1475	DNA binding
BLNIAS_RS09535	COG3328	transposase activity
BLNIAS_RS09540	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS09545	COG1175	transmembrane transport
BLNIAS_RS09555	COG1609	Transcriptional regulator
BLNIAS_RS09560	COG0366	Alpha amylase catalytic
BLNIAS_RS09570	COG3328	transposase activity
BLNIAS_RS09600	COG0617	tRNA 3'-terminal CCA addition
BLNIAS_RS09620	COG3583	domain protein
BLNIAS_RS09650	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLNIAS_RS09665	COG1472	Belongs to the glycosyl hydrolase 3 family
BLNIAS_RS09690	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLNIAS_RS09710	COG1215	transferase activity, transferring glycosyl groups
BLNIAS_RS09715	COG3842	ATPase activity
BLNIAS_RS09745	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLNIAS_RS09760	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BLNIAS_RS09785	COG0025	NhaP-type Na H and K H
BLNIAS_RS09790	COG0590	tRNA wobble adenosine to inosine editing
BLNIAS_RS09790	COG0037	tRNA processing
BLNIAS_RS09810	COG1175	transmembrane transport
BLNIAS_RS09815	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS09820	COG1609	Transcriptional regulator
BLNIAS_RS09825	COG1609	Transcriptional regulator
BLNIAS_RS09845	COG0395	ABC-type sugar transport system, permease component
BLNIAS_RS09850	COG0366	Alpha amylase catalytic
BLNIAS_RS09860	COG0366	Alpha amylase catalytic
BLNIAS_RS09865	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BLNIAS_RS09870	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BLNIAS_RS09890	COG2826	transposase and inactivated derivatives, IS30 family