locus-tag	class	description
KYE73_RS00010	COG0592	DNA-directed DNA polymerase activity
KYE73_RS00025	COG0187	DNA topoisomerase II activity
KYE73_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KYE73_RS00040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KYE73_RS00045	COG1970	mechanosensitive ion channel activity
KYE73_RS00070	COG0039	L-malate dehydrogenase activity
KYE73_RS00075	COG1253	flavin adenine dinucleotide binding
KYE73_RS00090	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KYE73_RS00100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KYE73_RS00105	COG0180	Tryptophanyl-tRNA synthetase
KYE73_RS00120	COG0058	SHG alpha-glucan phosphorylase activity
KYE73_RS00150	COG3764	Sortase (surface protein transpeptidase)
KYE73_RS00165	COG0515	serine threonine protein kinase
KYE73_RS00170	COG0768	penicillin binding
KYE73_RS00205	COG2197	response regulator
KYE73_RS00255	COG2197	response regulator
KYE73_RS00260	COG0343	queuine tRNA-ribosyltransferase activity
KYE73_RS00270	COG2217	Heavy metal translocating P-type atpase
KYE73_RS00275	COG0252	asparaginase activity
KYE73_RS00315	COG0191	fructose-bisphosphate aldolase activity
KYE73_RS00360	COG0366	Alpha amylase catalytic
KYE73_RS00385	COG0477	Major facilitator Superfamily
KYE73_RS00410	COG1609	Transcriptional regulator
KYE73_RS00420	COG1113	amino acid transport
KYE73_RS00430	COG0475	glutathione-regulated potassium exporter activity
KYE73_RS00430	COG0569	domain protein
KYE73_RS00435	COG1113	amino acid transport
KYE73_RS00455	COG0667	Aldo Keto reductase
KYE73_RS00460	COG1846	Transcriptional regulator
KYE73_RS00470	COG1132	(ABC) transporter
KYE73_RS00485	COG0672	)-iron permease
KYE73_RS00490	COG3470	protein probably involved in high-affinity Fe2 transport
KYE73_RS00510	COG1136	(ABC) transporter
KYE73_RS00510	COG0577	efflux transmembrane transporter activity
KYE73_RS00540	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KYE73_RS00560	COG1215	transferase activity, transferring glycosyl groups
KYE73_RS00565	COG1309	transcriptional regulator
KYE73_RS00585	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KYE73_RS00590	COG0305	Participates in initiation and elongation during chromosome replication
KYE73_RS00595	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KYE73_RS00600	COG3442	glutamine amidotransferase
KYE73_RS00625	COG1175	transmembrane transport
KYE73_RS00630	COG0395	ABC-type sugar transport system, permease component
KYE73_RS00645	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS00650	COG0584	glycerophosphoryl diester phosphodiesterase
KYE73_RS00665	COG0494	nUDIX hydrolase
KYE73_RS00665	COG0406	alpha-ribazole phosphatase activity
KYE73_RS00670	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KYE73_RS00710	COG1597	lipid kinase activity
KYE73_RS00720	COG1309	transcriptional regulator
KYE73_RS00740	COG0527	aspartate kinase activity
KYE73_RS00775	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS00780	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS00790	COG1609	Transcriptional regulator
KYE73_RS00795	COG3940	Belongs to the glycosyl hydrolase 43 family
KYE73_RS00805	COG4209	transmembrane transport
KYE73_RS00810	COG0395	ABC-type sugar transport system, permease component
KYE73_RS00830	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KYE73_RS00835	COG1260	myo-inositol-1-phosphate synthase
KYE73_RS00855	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KYE73_RS00855	COG1754	DNA topoisomerase type I activity
KYE73_RS00865	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KYE73_RS00870	COG1609	Transcriptional regulator
KYE73_RS00875	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYE73_RS00875	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KYE73_RS00880	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KYE73_RS00970	COG0167	dihydroorotate dehydrogenase activity
KYE73_RS00975	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KYE73_RS01010	COG3842	ATPase activity
KYE73_RS01035	COG1309	transcriptional regulator
KYE73_RS01040	COG0436	Aminotransferase
KYE73_RS01045	COG3265	gluconokinase activity
KYE73_RS01055	COG2270	Major facilitator Superfamily
KYE73_RS01075	COG0742	ribosomal rna small subunit methyltransferase
KYE73_RS01090	COG1837	Belongs to the UPF0109 family
KYE73_RS01120	COG0488	(ABC) transporter
KYE73_RS01170	COG0667	Aldo Keto reductase
KYE73_RS01175	COG0789	Transcriptional regulator
KYE73_RS01200	COG2348	transferase activity, transferring amino-acyl groups
KYE73_RS01230	COG0681	Belongs to the peptidase S26 family
KYE73_RS01235	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KYE73_RS01240	COG1136	(ABC) transporter
KYE73_RS01255	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KYE73_RS01260	COG1530	ribonuclease E activity
KYE73_RS01285	COG0436	Aminotransferase
KYE73_RS01295	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KYE73_RS01300	COG0250	Participates in transcription elongation, termination and antitermination
KYE73_RS01330	COG1268	BioY protein
KYE73_RS01335	COG4770	biotin carboxylase activity
KYE73_RS01340	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KYE73_RS01380	COG1704	LemA family
KYE73_RS01395	COG0826	peptidase U32
KYE73_RS01410	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KYE73_RS01420	COG3579	cysteine-type endopeptidase activity
KYE73_RS01425	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KYE73_RS01430	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KYE73_RS01440	COG5002	protein histidine kinase activity
KYE73_RS01445	COG0745	RESPONSE REGULATOR receiver
KYE73_RS01475	COG2252	PERMEase
KYE73_RS01515	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KYE73_RS01555	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KYE73_RS01560	COG0531	amino acid
KYE73_RS01575	COG4166	transmembrane transport
KYE73_RS01580	COG0601	transmembrane transport
KYE73_RS01585	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYE73_RS01590	COG0444	Belongs to the ABC transporter superfamily
KYE73_RS01595	COG4608	Belongs to the ABC transporter superfamily
KYE73_RS01600	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS01615	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS01620	COG2272	Belongs to the type-B carboxylesterase lipase family
KYE73_RS01630	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KYE73_RS01640	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KYE73_RS01645	COG1739	Uncharacterized protein family UPF0029
KYE73_RS01700	COG1063	alcohol dehydrogenase
KYE73_RS01710	COG1012	belongs to the aldehyde dehydrogenase family
KYE73_RS01710	COG1454	alcohol dehydrogenase
KYE73_RS01820	COG0201	protein transport
KYE73_RS01895	COG0196	riboflavin kinase activity
KYE73_RS01920	COG0328	RNA-DNA hybrid ribonuclease activity
KYE73_RS01945	COG3711	transcriptional antiterminator
KYE73_RS01950	COG1803	Methylglyoxal synthase
KYE73_RS01950	COG1597	lipid kinase activity
KYE73_RS01965	COG1397	ADP-ribosylglycohydrolase
KYE73_RS01970	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KYE73_RS01970	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KYE73_RS01995	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KYE73_RS02035	COG2814	Major facilitator Superfamily
KYE73_RS02045	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KYE73_RS02050	COG1609	Transcriptional regulator
KYE73_RS02065	COG1575	Belongs to the MenA family. Type 1 subfamily
KYE73_RS02075	COG4716	Myosin-crossreactive antigen
KYE73_RS02080	COG0704	Plays a role in the regulation of phosphate uptake
KYE73_RS02085	COG5002	protein histidine kinase activity
KYE73_RS02095	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KYE73_RS02100	COG3942	CHAP domain
KYE73_RS02100	COG1705	Flagellar rod assembly protein muramidase FlgJ
KYE73_RS02105	COG0791	NLP P60 protein
KYE73_RS02110	COG0589	response to stress
KYE73_RS02125	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KYE73_RS02140	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KYE73_RS02210	COG1716	ATPase activity
KYE73_RS02210	COG5001	Diguanylate cyclase
KYE73_RS02215	COG1454	alcohol dehydrogenase
KYE73_RS02220	COG1216	Glycosyl transferase, family 2
KYE73_RS02235	COG2027	D-alanyl-D-alanine carboxypeptidase
KYE73_RS02245	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KYE73_RS02250	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KYE73_RS02265	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KYE73_RS02275	COG1946	Acyl-CoA thioesterase
KYE73_RS02290	COG0242	peptide deformylase activity
KYE73_RS02305	COG1175	transmembrane transport
KYE73_RS02320	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS02340	COG2801	Transposase and inactivated derivatives
KYE73_RS02395	COG2873	o-acetylhomoserine
KYE73_RS02405	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS02420	COG1175	transmembrane transport
KYE73_RS02425	COG0395	ABC-type sugar transport system, permease component
KYE73_RS02430	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS02450	COG1070	Carbohydrate kinase
KYE73_RS02510	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KYE73_RS02530	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KYE73_RS02545	COG3590	peptidase
KYE73_RS02570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KYE73_RS02575	COG2884	Cell division ATP-binding protein ftsE
KYE73_RS02580	COG2177	Part of the ABC transporter FtsEX involved in
KYE73_RS02585	COG1388	LysM domain
KYE73_RS02585	COG3942	CHAP domain
KYE73_RS02620	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KYE73_RS02640	COG1175	transmembrane transport
KYE73_RS02645	COG0395	ABC-type sugar transport system, permease component
KYE73_RS02655	COG3534	alpha-L-arabinofuranosidase
KYE73_RS02670	COG0745	RESPONSE REGULATOR receiver
KYE73_RS02675	COG2205	protein histidine kinase activity
KYE73_RS02690	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KYE73_RS02695	COG0747	negative chemotaxis
KYE73_RS02705	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYE73_RS02730	COG1136	(ABC) transporter
KYE73_RS02730	COG0577	efflux transmembrane transporter activity
KYE73_RS02735	COG0514	ATP-dependent DNA helicase (RecQ)
KYE73_RS02750	COG0531	amino acid
KYE73_RS02755	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KYE73_RS02805	COG0765	amino acid transport
KYE73_RS02810	COG0765	amino acid transport
KYE73_RS02815	COG1126	abc transporter atp-binding protein
KYE73_RS02825	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KYE73_RS02830	COG1464	Belongs to the NlpA lipoprotein family
KYE73_RS02835	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KYE73_RS02840	COG2011	ABC-type metal ion transport system permease component
KYE73_RS02845	COG0436	Aminotransferase
KYE73_RS02875	COG1136	(ABC) transporter
KYE73_RS02875	COG0577	efflux transmembrane transporter activity
KYE73_RS02885	COG0577	efflux transmembrane transporter activity
KYE73_RS02890	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KYE73_RS02900	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KYE73_RS02905	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KYE73_RS02920	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYE73_RS02920	COG1522	sequence-specific DNA binding
KYE73_RS02925	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYE73_RS02930	COG0135	phosphoribosylanthranilate isomerase activity
KYE73_RS02945	COG0477	Major facilitator Superfamily
KYE73_RS02965	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KYE73_RS02975	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KYE73_RS03005	COG0385	Bile acid
KYE73_RS03050	COG0284	orotidine-5'-phosphate decarboxylase activity
KYE73_RS03075	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KYE73_RS03080	COG1011	Hydrolase
KYE73_RS03090	COG0560	Phosphoserine phosphatase
KYE73_RS03095	COG1222	aaa ATPase
KYE73_RS03100	COG4122	O-methyltransferase activity
KYE73_RS03115	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KYE73_RS03140	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KYE73_RS03180	COG0714	Associated with various cellular activities
KYE73_RS03215	COG0745	RESPONSE REGULATOR receiver
KYE73_RS03220	COG2205	protein histidine kinase activity
KYE73_RS03235	COG0589	response to stress
KYE73_RS03245	COG0402	S-adenosylhomocysteine deaminase activity
KYE73_RS03255	COG0477	Major facilitator Superfamily
KYE73_RS03265	COG1196	nuclear chromosome segregation
KYE73_RS03280	COG0765	amino acid transport
KYE73_RS03290	COG1126	abc transporter atp-binding protein
KYE73_RS03295	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYE73_RS03300	COG0765	amino acid transport
KYE73_RS03305	COG0765	amino acid transport
KYE73_RS03310	COG2326	polyphosphate kinase activity
KYE73_RS03325	COG0745	RESPONSE REGULATOR receiver
KYE73_RS03330	COG5000	phosphorelay sensor kinase activity
KYE73_RS03330	COG5002	protein histidine kinase activity
KYE73_RS03360	COG2814	Major facilitator Superfamily
KYE73_RS03405	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KYE73_RS03410	COG1053	succinate dehydrogenase
KYE73_RS03435	COG2873	o-acetylhomoserine
KYE73_RS03445	COG1122	ATPase activity
KYE73_RS03450	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KYE73_RS03460	COG1136	(ABC) transporter
KYE73_RS03465	COG1136	(ABC) transporter
KYE73_RS03465	COG0577	efflux transmembrane transporter activity
KYE73_RS03470	COG2197	response regulator
KYE73_RS03475	COG4585	Histidine kinase
KYE73_RS03485	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KYE73_RS03490	COG0012	GTP binding
KYE73_RS03500	COG2814	Major facilitator Superfamily
KYE73_RS03550	COG2207	Transcriptional regulator
KYE73_RS03550	COG1917	Cupin 2, conserved barrel domain protein
KYE73_RS03560	COG2233	PERMEase
KYE73_RS03565	COG4221	oxidoreductase activity
KYE73_RS03575	COG0390	transport system, permease component
KYE73_RS03580	COG1136	(ABC) transporter
KYE73_RS03580	COG0577	efflux transmembrane transporter activity
KYE73_RS03590	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KYE73_RS03595	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KYE73_RS03600	COG0300	oxidoreductase activity
KYE73_RS03605	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KYE73_RS03620	COG0363	glucosamine-6-phosphate deaminase activity
KYE73_RS03640	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KYE73_RS03645	COG1687	branched-chain amino acid
KYE73_RS03650	COG1966	Carbon starvation protein
KYE73_RS03720	COG1760	l-serine dehydratase
KYE73_RS03730	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KYE73_RS03755	COG1316	TRANSCRIPTIONal
KYE73_RS03760	COG1316	TRANSCRIPTIONal
KYE73_RS03790	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KYE73_RS03795	COG2205	protein histidine kinase activity
KYE73_RS03800	COG0745	RESPONSE REGULATOR receiver
KYE73_RS03810	COG1329	Transcriptional regulator
KYE73_RS03825	COG1121	(ABC) transporter
KYE73_RS03830	COG0803	Belongs to the bacterial solute-binding protein 9 family
KYE73_RS03840	COG0539	negative regulation of cytoplasmic translation
KYE73_RS03860	COG0469	pyruvate kinase activity
KYE73_RS03880	COG0626	cystathionine gamma-synthase activity
KYE73_RS03890	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYE73_RS03895	COG0765	amino acid transport
KYE73_RS03900	COG0210	DNA helicase
KYE73_RS03905	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KYE73_RS03910	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KYE73_RS03925	COG4974	Belongs to the 'phage' integrase family
KYE73_RS03935	COG0676	glucose-6-phosphate 1-epimerase activity
KYE73_RS03950	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KYE73_RS03985	COG0519	Catalyzes the synthesis of GMP from XMP
KYE73_RS04000	COG0857	belongs to the CobB CobQ family
KYE73_RS04000	COG0280	phosphate acetyltransferase
KYE73_RS04005	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KYE73_RS04010	COG2755	lipolytic protein G-D-S-L family
KYE73_RS04010	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KYE73_RS04040	COG0577	efflux transmembrane transporter activity
KYE73_RS04040	COG1136	(ABC) transporter
KYE73_RS04055	COG0588	phosphoglycerate mutase activity
KYE73_RS04100	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KYE73_RS04105	COG1523	belongs to the glycosyl hydrolase 13 family
KYE73_RS04125	COG0719	Fe-S assembly protein
KYE73_RS04130	COG0396	ATPase activity
KYE73_RS04145	COG2151	metal-sulfur cluster biosynthetic enzyme
KYE73_RS04165	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KYE73_RS04170	COG0537	adenosine 5'-monophosphoramidase activity
KYE73_RS04175	COG1702	phosphate starvation-inducible protein PhoH
KYE73_RS04200	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KYE73_RS04225	COG1309	transcriptional regulator
KYE73_RS04245	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KYE73_RS04285	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KYE73_RS04290	COG2860	membrane
KYE73_RS04310	COG1028	Short-chain dehydrogenase reductase Sdr
KYE73_RS04330	COG0069	glutamate synthase activity
KYE73_RS04330	COG0070	glutamate synthase
KYE73_RS04330	COG0067	glutamate synthase
KYE73_RS04345	COG0297	glycogen (starch) synthase activity
KYE73_RS04350	COG1119	ATPase activity
KYE73_RS04370	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KYE73_RS04390	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KYE73_RS04395	COG0284	orotidine-5'-phosphate decarboxylase activity
KYE73_RS04400	COG0543	2 iron, 2 sulfur cluster binding
KYE73_RS04405	COG0167	dihydroorotate dehydrogenase activity
KYE73_RS04415	COG0583	DNA-binding transcription factor activity
KYE73_RS04435	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KYE73_RS04440	COG0110	maltose O-acetyltransferase activity
KYE73_RS04445	COG0640	Transcriptional regulator
KYE73_RS04455	COG1011	Hydrolase
KYE73_RS04490	COG1022	Amp-dependent synthetase and ligase
KYE73_RS04505	COG0516	GMP reductase activity
KYE73_RS04530	COG0799	negative regulation of ribosome biogenesis
KYE73_RS04535	COG0406	alpha-ribazole phosphatase activity
KYE73_RS04550	COG3177	Filamentation induced by cAMP protein fic
KYE73_RS04570	COG0406	alpha-ribazole phosphatase activity
KYE73_RS04575	COG0598	Magnesium transport protein CorA
KYE73_RS04580	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYE73_RS04590	COG1596	polysaccharide export
KYE73_RS04590	COG1555	photosystem II stabilization
KYE73_RS04595	COG2333	competence protein COMEC
KYE73_RS04595	COG0658	competence protein
KYE73_RS04605	COG0802	atpase or kinase
KYE73_RS04615	COG0456	acetyltransferase
KYE73_RS04630	COG0456	acetyltransferase
KYE73_RS04650	COG1063	alcohol dehydrogenase
KYE73_RS04660	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KYE73_RS04700	COG3579	cysteine-type endopeptidase activity
KYE73_RS04705	COG0517	IMP dehydrogenase activity
KYE73_RS04710	COG0488	(ABC) transporter
KYE73_RS04715	COG1335	isochorismatase
KYE73_RS04760	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KYE73_RS04785	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KYE73_RS04790	COG0561	phosphatase activity
KYE73_RS04795	COG0436	Aminotransferase
KYE73_RS04805	COG3201	nicotinamide mononucleotide transporter
KYE73_RS04820	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KYE73_RS04895	COG1716	ATPase activity
KYE73_RS04960	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KYE73_RS04985	COG0045	succinate-CoA ligase (ADP-forming) activity
KYE73_RS05020	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KYE73_RS05060	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KYE73_RS05075	COG0133	tryptophan synthase activity
KYE73_RS05130	COG1022	Amp-dependent synthetase and ligase
KYE73_RS05265	COG3177	Filamentation induced by cAMP protein fic
KYE73_RS05425	COG0551	DNA topoisomerase type I activity
KYE73_RS05425	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KYE73_RS05440	COG4115	mRNA cleavage
KYE73_RS05445	COG2161	toxin-antitoxin pair type II binding
KYE73_RS05455	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KYE73_RS05475	COG0629	single-stranded DNA binding
KYE73_RS05485	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
KYE73_RS05610	COG0514	ATP-dependent DNA helicase (RecQ)
KYE73_RS05635	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
KYE73_RS05765	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KYE73_RS05870	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYE73_RS05875	COG0497	DNA recombination
KYE73_RS05885	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KYE73_RS05890	COG0569	domain protein
KYE73_RS05985	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KYE73_RS05995	COG1611	Belongs to the LOG family
KYE73_RS06030	COG1122	ATPase activity
KYE73_RS06035	COG4721	ABC-type cobalt transport system, permease component
KYE73_RS06065	COG1122	ATPase activity
KYE73_RS06070	COG0436	Aminotransferase
KYE73_RS06085	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KYE73_RS06110	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KYE73_RS06205	COG0667	Aldo Keto reductase
KYE73_RS06230	COG2197	response regulator
KYE73_RS06235	COG0515	serine threonine protein kinase
KYE73_RS06240	COG1132	(ABC) transporter
KYE73_RS06245	COG1132	(ABC) transporter
KYE73_RS06270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
KYE73_RS06285	COG1882	Formate acetyltransferase
KYE73_RS06300	COG1473	amidohydrolase
KYE73_RS06310	COG1464	Belongs to the NlpA lipoprotein family
KYE73_RS06315	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KYE73_RS06320	COG2011	ABC-type metal ion transport system permease component
KYE73_RS06345	COG2801	Transposase and inactivated derivatives
KYE73_RS06365	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KYE73_RS06370	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KYE73_RS06395	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KYE73_RS06400	COG1201	RNA secondary structure unwinding
KYE73_RS06405	COG3655	Transcriptional regulator
KYE73_RS06425	COG0187	DNA topoisomerase II activity
KYE73_RS06430	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KYE73_RS06440	COG0142	geranyltranstransferase activity
KYE73_RS06460	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KYE73_RS06470	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KYE73_RS06495	COG1396	sequence-specific DNA binding
KYE73_RS06500	COG1058	Belongs to the CinA family
KYE73_RS06500	COG1546	Belongs to the CinA family
KYE73_RS06505	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KYE73_RS06525	COG2357	RelA SpoT domain protein
KYE73_RS06535	COG0670	Belongs to the BI1 family
KYE73_RS06550	COG2197	response regulator
KYE73_RS06565	COG4585	Histidine kinase
KYE73_RS06570	COG1131	(ABC) transporter
KYE73_RS06585	COG3292	Two component regulator propeller
KYE73_RS06585	COG2205	protein histidine kinase activity
KYE73_RS06585	COG0745	RESPONSE REGULATOR receiver
KYE73_RS06590	COG0110	maltose O-acetyltransferase activity
KYE73_RS06595	COG0534	Mate efflux family protein
KYE73_RS06600	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KYE73_RS06630	COG0708	Exodeoxyribonuclease III
KYE73_RS06640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYE73_RS06645	COG0601	transmembrane transport
KYE73_RS06650	COG4166	transmembrane transport
KYE73_RS06655	COG4166	transmembrane transport
KYE73_RS06670	COG0287	Prephenate dehydrogenase
KYE73_RS06685	COG1217	gtp-binding protein TYPA
KYE73_RS06690	COG0477	Major facilitator Superfamily
KYE73_RS06720	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KYE73_RS06735	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KYE73_RS06755	COG1595	DNA-templated transcription, initiation
KYE73_RS06770	COG0285	dihydrofolate synthase activity
KYE73_RS06775	COG0006	proline dipeptidase activity
KYE73_RS06795	COG0601	transmembrane transport
KYE73_RS06810	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYE73_RS06860	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KYE73_RS06870	COG0768	penicillin binding
KYE73_RS06895	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KYE73_RS06925	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KYE73_RS06930	COG2813	Specifically methylates the guanine in position
KYE73_RS06935	COG1643	Atp-dependent helicase
KYE73_RS06955	COG1136	(ABC) transporter
KYE73_RS06960	COG2814	Major facilitator Superfamily
KYE73_RS07010	COG0587	DNA-directed DNA polymerase activity
KYE73_RS07040	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KYE73_RS07070	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KYE73_RS07080	COG1459	type II secretion system
KYE73_RS07085	COG4969	Belongs to the N-Me-Phe pilin family
KYE73_RS07100	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KYE73_RS07130	COG0351	phosphomethylpyrimidine kinase
KYE73_RS07155	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KYE73_RS07210	COG3480	Lon protease (S16) C-terminal proteolytic domain
KYE73_RS07235	COG0613	PHP domain protein
KYE73_RS07245	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KYE73_RS07260	COG4166	transmembrane transport
KYE73_RS07335	COG3513	CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). In type II CRISPR systems correct processing of pre-crRNA requires a trans-encoded small RNA (tracrRNA), endogenous ribonuclease 3 (rnc) and this protein. The tracrRNA serves as a guide for ribonuclease 3-aided processing of pre-crRNA. Subsequently Cas9 crRNA tracrRNA endonucleolytically cleaves linear or circular dsDNA target complementary to the spacer
KYE73_RS07350	COG1609	Transcriptional regulator
KYE73_RS07355	COG1132	(ABC) transporter
KYE73_RS07360	COG1132	(ABC) transporter
KYE73_RS07380	COG1929	Belongs to the glycerate kinase type-1 family
KYE73_RS07385	COG2211	Major facilitator Superfamily
KYE73_RS07390	COG3250	beta-galactosidase activity
KYE73_RS07400	COG1609	Transcriptional regulator
KYE73_RS07415	COG0477	Major facilitator Superfamily
KYE73_RS07425	COG1309	transcriptional regulator
KYE73_RS07435	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE73_RS07445	COG2211	Major facilitator Superfamily
KYE73_RS07460	COG1309	transcriptional regulator
KYE73_RS07475	COG0602	queuosine metabolic process
KYE73_RS07480	COG1328	CTP reductase activity
KYE73_RS07480	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KYE73_RS07485	COG1570	exodeoxyribonuclease VII activity
KYE73_RS07490	COG1722	exodeoxyribonuclease VII activity
KYE73_RS07525	COG0248	Ppx GppA phosphatase
KYE73_RS07530	COG0436	Aminotransferase
KYE73_RS07545	COG0210	DNA helicase
KYE73_RS07605	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KYE73_RS07620	COG1937	Protein conserved in bacteria
KYE73_RS07645	COG2815	serine threonine protein kinase
KYE73_RS07645	COG0515	serine threonine protein kinase
KYE73_RS07655	COG0714	Associated with various cellular activities
KYE73_RS07670	COG0631	protein serine/threonine phosphatase activity
KYE73_RS07700	COG1194	a g-specific adenine glycosylase
KYE73_RS07705	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KYE73_RS07720	COG1621	beta-fructofuranosidase activity
KYE73_RS07735	COG0395	ABC-type sugar transport system, permease component
KYE73_RS07740	COG4209	transmembrane transport
KYE73_RS07750	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KYE73_RS07760	COG1349	DNA-binding transcription factor activity
KYE73_RS07765	COG0167	dihydroorotate dehydrogenase activity
KYE73_RS07770	COG1902	pentaerythritol trinitrate reductase activity
KYE73_RS07775	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KYE73_RS07775	COG4499	WXG100 protein secretion system (Wss), protein YukC
KYE73_RS07785	COG0095	Lipoate-protein ligase
KYE73_RS07800	COG1770	oligopeptidase
KYE73_RS07830	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KYE73_RS07850	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KYE73_RS07855	COG1501	Belongs to the glycosyl hydrolase 31 family
KYE73_RS07860	COG0395	ABC-type sugar transport system, permease component
KYE73_RS07865	COG1175	transmembrane transport
KYE73_RS07875	COG1609	Transcriptional regulator
KYE73_RS07880	COG5290	Psort location Cytoplasmic, score
KYE73_RS07975	COG1216	Glycosyl transferase, family 2
KYE73_RS07985	COG0438	transferase activity, transferring glycosyl groups
KYE73_RS07990	COG0438	transferase activity, transferring glycosyl groups
KYE73_RS08005	COG1216	Glycosyl transferase, family 2
KYE73_RS08005	COG1442	glycosyl transferase family 8
KYE73_RS08065	COG0489	protein tyrosine kinase activity
KYE73_RS08075	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KYE73_RS08090	COG2814	Major facilitator Superfamily
KYE73_RS08095	COG3300	MHYT domain
KYE73_RS08095	COG5001	Diguanylate cyclase
KYE73_RS08105	COG0656	L-ascorbic acid biosynthetic process
KYE73_RS08115	COG1609	Transcriptional regulator
KYE73_RS08125	COG0395	ABC-type sugar transport system, permease component
KYE73_RS08130	COG1175	transmembrane transport
KYE73_RS08135	COG1653	transport
KYE73_RS08150	COG4988	ABC transporter
KYE73_RS08175	COG1609	Transcriptional regulator
KYE73_RS08185	COG0083	homoserine kinase activity
KYE73_RS08190	COG0460	homoserine dehydrogenase
KYE73_RS08205	COG0833	amino acid
KYE73_RS08210	COG0251	oxidation-reduction process
KYE73_RS08240	COG0545	Peptidyl-prolyl cis-trans isomerase
KYE73_RS08285	COG0356	it plays a direct role in the translocation of protons across the membrane
KYE73_RS08305	COG0679	Auxin Efflux Carrier
KYE73_RS08310	COG0028	Belongs to the TPP enzyme family
KYE73_RS08325	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KYE73_RS08340	COG0745	RESPONSE REGULATOR receiver
KYE73_RS08350	COG0747	negative chemotaxis
KYE73_RS08365	COG1605	Chorismate mutase
KYE73_RS08365	COG0287	Prephenate dehydrogenase
KYE73_RS08370	COG1522	sequence-specific DNA binding
KYE73_RS08430	COG1322	Protein conserved in bacteria
KYE73_RS08445	COG0179	Fumarylacetoacetate (FAA) hydrolase
KYE73_RS08450	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KYE73_RS08480	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KYE73_RS08515	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYE73_RS08540	COG1373	ATPase (AAA superfamily
KYE73_RS08545	COG1088	dTDP-glucose 4,6-dehydratase activity
KYE73_RS08565	COG1368	sulfuric ester hydrolase activity
KYE73_RS08575	COG0463	Glycosyl transferase, family 2
KYE73_RS08590	COG1088	dTDP-glucose 4,6-dehydratase activity
KYE73_RS08605	COG1442	glycosyl transferase family 8
KYE73_RS08610	COG1216	Glycosyl transferase, family 2
KYE73_RS08610	COG0438	transferase activity, transferring glycosyl groups
KYE73_RS08630	COG0438	transferase activity, transferring glycosyl groups
KYE73_RS08630	COG1216	Glycosyl transferase, family 2
KYE73_RS08635	COG1215	transferase activity, transferring glycosyl groups
KYE73_RS08640	COG1442	glycosyl transferase family 8
KYE73_RS08735	COG1136	(ABC) transporter
KYE73_RS08755	COG0084	hydrolase, TatD family'
KYE73_RS08785	COG1132	(ABC) transporter
KYE73_RS08790	COG1132	(ABC) transporter
KYE73_RS08825	COG1609	Transcriptional regulator
KYE73_RS08845	COG1940	carbohydrate kinase activity
KYE73_RS08850	COG0395	ABC-type sugar transport system, permease component
KYE73_RS08855	COG1175	transmembrane transport
KYE73_RS08875	COG3250	beta-galactosidase activity
KYE73_RS08915	COG0586	Pfam SNARE associated Golgi protein
KYE73_RS08925	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYE73_RS08935	COG0789	Transcriptional regulator
KYE73_RS08940	COG0484	heat shock protein binding
KYE73_RS08965	COG0730	response to heat
KYE73_RS08970	COG1609	Transcriptional regulator
KYE73_RS08980	COG0546	phosphoglycolate phosphatase activity
KYE73_RS08985	COG1523	belongs to the glycosyl hydrolase 13 family
KYE73_RS09020	COG1609	Transcriptional regulator
KYE73_RS09025	COG1609	Transcriptional regulator
KYE73_RS09030	COG0366	Alpha amylase catalytic
KYE73_RS09040	COG0588	phosphoglycerate mutase activity
KYE73_RS09080	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KYE73_RS09085	COG3250	beta-galactosidase activity
KYE73_RS09120	COG3842	ATPase activity
KYE73_RS09125	COG2204	response regulator
KYE73_RS09185	COG1472	Belongs to the glycosyl hydrolase 3 family
KYE73_RS09210	COG0577	efflux transmembrane transporter activity
KYE73_RS09265	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KYE73_RS09270	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KYE73_RS09275	COG0366	Alpha amylase catalytic
KYE73_RS09280	COG0395	ABC-type sugar transport system, permease component
KYE73_RS09285	COG1175	transmembrane transport
KYE73_RS09290	COG1653	transport
KYE73_RS09305	COG0037	tRNA processing
KYE73_RS09305	COG0590	tRNA wobble adenosine to inosine editing
KYE73_RS09310	COG0025	NhaP-type Na H and K H
KYE73_RS09360	COG3583	domain protein
KYE73_RS09380	COG0617	tRNA 3'-terminal CCA addition
KYE73_RS09405	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KYE73_RS09410	COG0492	ferredoxin-NADP+ reductase activity
KYE73_RS09420	COG1192	Involved in chromosome partitioning
KYE73_RS09430	COG1847	R3H domain protein
KYE73_RS09455	COG1979	alcohol dehydrogenase
KYE73_RS09500	COG2814	Major facilitator Superfamily