locus-tag	class	description
KYE74_RS00010	COG0592	DNA-directed DNA polymerase activity
KYE74_RS00025	COG0187	DNA topoisomerase II activity
KYE74_RS00030	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KYE74_RS00040	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
KYE74_RS00045	COG1970	mechanosensitive ion channel activity
KYE74_RS00070	COG0039	L-malate dehydrogenase activity
KYE74_RS00075	COG1253	flavin adenine dinucleotide binding
KYE74_RS00090	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
KYE74_RS00100	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
KYE74_RS00105	COG0180	Tryptophanyl-tRNA synthetase
KYE74_RS00120	COG0058	SHG alpha-glucan phosphorylase activity
KYE74_RS00150	COG3764	Sortase (surface protein transpeptidase)
KYE74_RS00165	COG0515	serine threonine protein kinase
KYE74_RS00170	COG0768	penicillin binding
KYE74_RS00205	COG2197	response regulator
KYE74_RS00250	COG2197	response regulator
KYE74_RS00255	COG0343	queuine tRNA-ribosyltransferase activity
KYE74_RS00265	COG2217	Heavy metal translocating P-type atpase
KYE74_RS00270	COG0252	asparaginase activity
KYE74_RS00310	COG0191	fructose-bisphosphate aldolase activity
KYE74_RS00355	COG0366	Alpha amylase catalytic
KYE74_RS00380	COG0477	Major facilitator Superfamily
KYE74_RS00405	COG1609	Transcriptional regulator
KYE74_RS00415	COG1113	amino acid transport
KYE74_RS00425	COG0475	glutathione-regulated potassium exporter activity
KYE74_RS00425	COG0569	domain protein
KYE74_RS00455	COG1113	amino acid transport
KYE74_RS00475	COG0667	Aldo Keto reductase
KYE74_RS00480	COG1846	Transcriptional regulator
KYE74_RS00490	COG1132	(ABC) transporter
KYE74_RS00505	COG0672	)-iron permease
KYE74_RS00510	COG3470	protein probably involved in high-affinity Fe2 transport
KYE74_RS00530	COG1136	(ABC) transporter
KYE74_RS00530	COG0577	efflux transmembrane transporter activity
KYE74_RS00560	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
KYE74_RS00580	COG1215	transferase activity, transferring glycosyl groups
KYE74_RS00585	COG1309	transcriptional regulator
KYE74_RS00605	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
KYE74_RS00610	COG0305	Participates in initiation and elongation during chromosome replication
KYE74_RS00615	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KYE74_RS00620	COG3442	glutamine amidotransferase
KYE74_RS00645	COG1175	transmembrane transport
KYE74_RS00650	COG0395	ABC-type sugar transport system, permease component
KYE74_RS00665	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE74_RS00670	COG0584	glycerophosphoryl diester phosphodiesterase
KYE74_RS00685	COG0494	nUDIX hydrolase
KYE74_RS00685	COG0406	alpha-ribazole phosphatase activity
KYE74_RS00690	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
KYE74_RS00730	COG1597	lipid kinase activity
KYE74_RS00740	COG1309	transcriptional regulator
KYE74_RS00760	COG0527	aspartate kinase activity
KYE74_RS00795	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE74_RS00800	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE74_RS00810	COG1609	Transcriptional regulator
KYE74_RS00815	COG3940	Belongs to the glycosyl hydrolase 43 family
KYE74_RS00820	COG1653	transport
KYE74_RS00825	COG1175	transmembrane transport
KYE74_RS00830	COG0395	ABC-type sugar transport system, permease component
KYE74_RS00840	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KYE74_RS00845	COG1260	myo-inositol-1-phosphate synthase
KYE74_RS00865	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
KYE74_RS00865	COG1754	DNA topoisomerase type I activity
KYE74_RS00875	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
KYE74_RS00880	COG1609	Transcriptional regulator
KYE74_RS00885	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KYE74_RS00885	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
KYE74_RS00890	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
KYE74_RS00980	COG0167	dihydroorotate dehydrogenase activity
KYE74_RS00985	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
KYE74_RS01020	COG3842	ATPase activity
KYE74_RS01045	COG1309	transcriptional regulator
KYE74_RS01050	COG0436	Aminotransferase
KYE74_RS01055	COG1023	phosphogluconate dehydrogenase (decarboxylating) activity
KYE74_RS01065	COG3265	gluconokinase activity
KYE74_RS01075	COG2270	Major facilitator Superfamily
KYE74_RS01095	COG0742	ribosomal rna small subunit methyltransferase
KYE74_RS01125	COG1837	Belongs to the UPF0109 family
KYE74_RS01155	COG0488	(ABC) transporter
KYE74_RS01205	COG0667	Aldo Keto reductase
KYE74_RS01210	COG0789	Transcriptional regulator
KYE74_RS01235	COG2348	transferase activity, transferring amino-acyl groups
KYE74_RS01265	COG0681	Belongs to the peptidase S26 family
KYE74_RS01270	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
KYE74_RS01275	COG1136	(ABC) transporter
KYE74_RS01290	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
KYE74_RS01295	COG1530	ribonuclease E activity
KYE74_RS01320	COG0436	Aminotransferase
KYE74_RS01330	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KYE74_RS01335	COG0250	Participates in transcription elongation, termination and antitermination
KYE74_RS01365	COG1268	BioY protein
KYE74_RS01370	COG4770	biotin carboxylase activity
KYE74_RS01375	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
KYE74_RS01415	COG1704	LemA family
KYE74_RS01430	COG0826	peptidase U32
KYE74_RS01435	COG1496	oxidoreductase activity
KYE74_RS01445	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
KYE74_RS01455	COG3579	cysteine-type endopeptidase activity
KYE74_RS01460	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KYE74_RS01465	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
KYE74_RS01475	COG5002	protein histidine kinase activity
KYE74_RS01480	COG0745	RESPONSE REGULATOR receiver
KYE74_RS01510	COG2252	PERMEase
KYE74_RS01550	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
KYE74_RS01590	COG0812	UDP-N-acetylmuramate dehydrogenase activity
KYE74_RS01595	COG0531	amino acid
KYE74_RS01610	COG4166	transmembrane transport
KYE74_RS01615	COG0601	transmembrane transport
KYE74_RS01620	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYE74_RS01625	COG0444	Belongs to the ABC transporter superfamily
KYE74_RS01630	COG4608	Belongs to the ABC transporter superfamily
KYE74_RS01635	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE74_RS01650	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE74_RS01655	COG2272	Belongs to the type-B carboxylesterase lipase family
KYE74_RS01665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KYE74_RS01675	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KYE74_RS01680	COG1739	Uncharacterized protein family UPF0029
KYE74_RS01725	COG1063	alcohol dehydrogenase
KYE74_RS01735	COG1454	alcohol dehydrogenase
KYE74_RS01735	COG1012	belongs to the aldehyde dehydrogenase family
KYE74_RS01845	COG0201	protein transport
KYE74_RS01930	COG0196	riboflavin kinase activity
KYE74_RS01955	COG0328	RNA-DNA hybrid ribonuclease activity
KYE74_RS01980	COG3711	transcriptional antiterminator
KYE74_RS01985	COG1597	lipid kinase activity
KYE74_RS01985	COG1803	Methylglyoxal synthase
KYE74_RS02000	COG1397	ADP-ribosylglycohydrolase
KYE74_RS02005	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
KYE74_RS02005	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
KYE74_RS02030	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
KYE74_RS02070	COG2814	Major facilitator Superfamily
KYE74_RS02080	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
KYE74_RS02085	COG1609	Transcriptional regulator
KYE74_RS02100	COG1575	Belongs to the MenA family. Type 1 subfamily
KYE74_RS02110	COG4716	Myosin-crossreactive antigen
KYE74_RS02115	COG0704	Plays a role in the regulation of phosphate uptake
KYE74_RS02120	COG5002	protein histidine kinase activity
KYE74_RS02130	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
KYE74_RS02135	COG3942	CHAP domain
KYE74_RS02135	COG1705	Flagellar rod assembly protein muramidase FlgJ
KYE74_RS02140	COG0791	NLP P60 protein
KYE74_RS02145	COG0589	response to stress
KYE74_RS02160	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
KYE74_RS02175	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
KYE74_RS02245	COG2203	Gaf domain
KYE74_RS02245	COG3706	GGDEF domain
KYE74_RS02245	COG4251	negative regulation of phosphorylation
KYE74_RS02245	COG5001	Diguanylate cyclase
KYE74_RS02250	COG1454	alcohol dehydrogenase
KYE74_RS02255	COG1216	Glycosyl transferase, family 2
KYE74_RS02270	COG2027	D-alanyl-D-alanine carboxypeptidase
KYE74_RS02280	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
KYE74_RS02285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
KYE74_RS02300	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
KYE74_RS02310	COG1946	Acyl-CoA thioesterase
KYE74_RS02325	COG0242	peptide deformylase activity
KYE74_RS02370	COG2873	o-acetylhomoserine
KYE74_RS02380	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE74_RS02385	COG1609	Transcriptional regulator
KYE74_RS02395	COG1175	transmembrane transport
KYE74_RS02400	COG0395	ABC-type sugar transport system, permease component
KYE74_RS02405	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE74_RS02425	COG1070	Carbohydrate kinase
KYE74_RS02485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
KYE74_RS02505	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KYE74_RS02520	COG3590	peptidase
KYE74_RS02545	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
KYE74_RS02550	COG2884	Cell division ATP-binding protein ftsE
KYE74_RS02555	COG2177	Part of the ABC transporter FtsEX involved in
KYE74_RS02560	COG3942	CHAP domain
KYE74_RS02560	COG1388	LysM domain
KYE74_RS02595	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
KYE74_RS02625	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
KYE74_RS02630	COG0747	negative chemotaxis
KYE74_RS02640	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYE74_RS02665	COG1136	(ABC) transporter
KYE74_RS02665	COG0577	efflux transmembrane transporter activity
KYE74_RS02670	COG0514	ATP-dependent DNA helicase (RecQ)
KYE74_RS02685	COG0531	amino acid
KYE74_RS02690	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
KYE74_RS02745	COG0765	amino acid transport
KYE74_RS02750	COG1126	abc transporter atp-binding protein
KYE74_RS02760	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
KYE74_RS02765	COG1464	Belongs to the NlpA lipoprotein family
KYE74_RS02770	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
KYE74_RS02775	COG2011	ABC-type metal ion transport system permease component
KYE74_RS02780	COG0436	Aminotransferase
KYE74_RS02810	COG0577	efflux transmembrane transporter activity
KYE74_RS02810	COG1136	(ABC) transporter
KYE74_RS02820	COG0577	efflux transmembrane transporter activity
KYE74_RS02825	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
KYE74_RS02835	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
KYE74_RS02840	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
KYE74_RS02855	COG1522	sequence-specific DNA binding
KYE74_RS02855	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYE74_RS02860	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYE74_RS02865	COG0135	phosphoribosylanthranilate isomerase activity
KYE74_RS02880	COG0477	Major facilitator Superfamily
KYE74_RS02900	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
KYE74_RS02910	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
KYE74_RS02940	COG0385	Bile acid
KYE74_RS02985	COG0284	orotidine-5'-phosphate decarboxylase activity
KYE74_RS03010	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
KYE74_RS03015	COG1011	Hydrolase
KYE74_RS03025	COG0560	Phosphoserine phosphatase
KYE74_RS03030	COG1222	aaa ATPase
KYE74_RS03050	COG0638	Catalyzes the covalent attachment of the prokaryotic ubiquitin-like protein modifier Pup to the proteasomal substrate proteins, thereby targeting them for proteasomal degradation. This tagging system is termed pupylation. The ligation reaction involves the side-chain carboxylate of the C-terminal glutamate of Pup and the side-chain amino group of a substrate lysine
KYE74_RS03075	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
KYE74_RS03115	COG0714	Associated with various cellular activities
KYE74_RS03150	COG0745	RESPONSE REGULATOR receiver
KYE74_RS03155	COG2205	protein histidine kinase activity
KYE74_RS03170	COG0589	response to stress
KYE74_RS03180	COG0402	S-adenosylhomocysteine deaminase activity
KYE74_RS03190	COG0477	Major facilitator Superfamily
KYE74_RS03200	COG1196	nuclear chromosome segregation
KYE74_RS03215	COG0765	amino acid transport
KYE74_RS03225	COG1126	abc transporter atp-binding protein
KYE74_RS03230	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYE74_RS03235	COG0765	amino acid transport
KYE74_RS03240	COG0765	amino acid transport
KYE74_RS03245	COG2326	polyphosphate kinase activity
KYE74_RS03260	COG0745	RESPONSE REGULATOR receiver
KYE74_RS03265	COG5002	protein histidine kinase activity
KYE74_RS03265	COG5000	phosphorelay sensor kinase activity
KYE74_RS03295	COG0477	Major facilitator Superfamily
KYE74_RS03340	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
KYE74_RS03345	COG1053	succinate dehydrogenase
KYE74_RS03370	COG2873	o-acetylhomoserine
KYE74_RS03380	COG1122	ATPase activity
KYE74_RS03385	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
KYE74_RS03395	COG1136	(ABC) transporter
KYE74_RS03400	COG1136	(ABC) transporter
KYE74_RS03400	COG0577	efflux transmembrane transporter activity
KYE74_RS03405	COG2197	response regulator
KYE74_RS03410	COG4585	Histidine kinase
KYE74_RS03420	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
KYE74_RS03425	COG0012	GTP binding
KYE74_RS03435	COG2814	Major facilitator Superfamily
KYE74_RS03485	COG2207	Transcriptional regulator
KYE74_RS03485	COG1917	Cupin 2, conserved barrel domain protein
KYE74_RS03495	COG2233	PERMEase
KYE74_RS03500	COG4221	oxidoreductase activity
KYE74_RS03510	COG0390	transport system, permease component
KYE74_RS03515	COG1136	(ABC) transporter
KYE74_RS03515	COG0577	efflux transmembrane transporter activity
KYE74_RS03530	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
KYE74_RS03535	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
KYE74_RS03540	COG0300	oxidoreductase activity
KYE74_RS03545	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
KYE74_RS03560	COG0363	glucosamine-6-phosphate deaminase activity
KYE74_RS03575	COG1296	Branched-chain amino acid permease (Azaleucine resistance)
KYE74_RS03580	COG1687	branched-chain amino acid
KYE74_RS03585	COG1966	Carbon starvation protein
KYE74_RS03655	COG1760	l-serine dehydratase
KYE74_RS03665	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
KYE74_RS03690	COG1316	TRANSCRIPTIONal
KYE74_RS03695	COG1316	TRANSCRIPTIONal
KYE74_RS03725	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
KYE74_RS03730	COG2205	protein histidine kinase activity
KYE74_RS03735	COG0745	RESPONSE REGULATOR receiver
KYE74_RS03745	COG1329	Transcriptional regulator
KYE74_RS03760	COG1121	(ABC) transporter
KYE74_RS03765	COG0803	Belongs to the bacterial solute-binding protein 9 family
KYE74_RS03775	COG0539	negative regulation of cytoplasmic translation
KYE74_RS03795	COG0469	pyruvate kinase activity
KYE74_RS03815	COG0626	cystathionine gamma-synthase activity
KYE74_RS03825	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYE74_RS03830	COG0765	amino acid transport
KYE74_RS03835	COG0210	DNA helicase
KYE74_RS03840	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
KYE74_RS03845	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
KYE74_RS03855	COG0732	type I restriction modification DNA specificity domain
KYE74_RS03860	COG4974	Belongs to the 'phage' integrase family
KYE74_RS03865	COG0732	type I restriction modification DNA specificity domain
KYE74_RS03870	COG0676	glucose-6-phosphate 1-epimerase activity
KYE74_RS03885	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
KYE74_RS03910	COG4974	Belongs to the 'phage' integrase family
KYE74_RS03970	COG1475	DNA binding
KYE74_RS04160	COG0582	viral genome integration into host DNA
KYE74_RS04220	COG0519	Catalyzes the synthesis of GMP from XMP
KYE74_RS04235	COG0857	belongs to the CobB CobQ family
KYE74_RS04235	COG0280	phosphate acetyltransferase
KYE74_RS04240	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
KYE74_RS04245	COG2755	lipolytic protein G-D-S-L family
KYE74_RS04245	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
KYE74_RS04275	COG1136	(ABC) transporter
KYE74_RS04275	COG0577	efflux transmembrane transporter activity
KYE74_RS04290	COG0588	phosphoglycerate mutase activity
KYE74_RS04335	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
KYE74_RS04340	COG1523	belongs to the glycosyl hydrolase 13 family
KYE74_RS04360	COG0719	Fe-S assembly protein
KYE74_RS04365	COG0396	ATPase activity
KYE74_RS04380	COG2151	metal-sulfur cluster biosynthetic enzyme
KYE74_RS04400	COG1385	rRNA (uridine-N3-)-methyltransferase activity
KYE74_RS04405	COG0537	adenosine 5'-monophosphoramidase activity
KYE74_RS04410	COG1702	phosphate starvation-inducible protein PhoH
KYE74_RS04435	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
KYE74_RS04460	COG1309	transcriptional regulator
KYE74_RS04480	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
KYE74_RS04525	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
KYE74_RS04530	COG2860	membrane
KYE74_RS04550	COG1028	Short-chain dehydrogenase reductase Sdr
KYE74_RS04570	COG0070	glutamate synthase
KYE74_RS04570	COG0069	glutamate synthase activity
KYE74_RS04570	COG0067	glutamate synthase
KYE74_RS04585	COG0297	glycogen (starch) synthase activity
KYE74_RS04590	COG1119	ATPase activity
KYE74_RS04610	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
KYE74_RS04630	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
KYE74_RS04635	COG0284	orotidine-5'-phosphate decarboxylase activity
KYE74_RS04640	COG0543	2 iron, 2 sulfur cluster binding
KYE74_RS04645	COG0167	dihydroorotate dehydrogenase activity
KYE74_RS04655	COG0583	DNA-binding transcription factor activity
KYE74_RS04675	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KYE74_RS04680	COG0110	maltose O-acetyltransferase activity
KYE74_RS04685	COG0640	Transcriptional regulator
KYE74_RS04695	COG1011	Hydrolase
KYE74_RS04730	COG1022	Amp-dependent synthetase and ligase
KYE74_RS04745	COG0516	GMP reductase activity
KYE74_RS04770	COG0799	negative regulation of ribosome biogenesis
KYE74_RS04775	COG0406	alpha-ribazole phosphatase activity
KYE74_RS04790	COG3177	Filamentation induced by cAMP protein fic
KYE74_RS04810	COG0406	alpha-ribazole phosphatase activity
KYE74_RS04815	COG0598	Magnesium transport protein CorA
KYE74_RS04820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
KYE74_RS04830	COG1596	polysaccharide export
KYE74_RS04830	COG1555	photosystem II stabilization
KYE74_RS04835	COG0658	competence protein
KYE74_RS04835	COG2333	competence protein COMEC
KYE74_RS04845	COG0802	atpase or kinase
KYE74_RS04870	COG0456	acetyltransferase
KYE74_RS04890	COG1063	alcohol dehydrogenase
KYE74_RS04900	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
KYE74_RS04940	COG3579	cysteine-type endopeptidase activity
KYE74_RS04945	COG0517	IMP dehydrogenase activity
KYE74_RS04950	COG0488	(ABC) transporter
KYE74_RS04955	COG1335	isochorismatase
KYE74_RS05000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
KYE74_RS05025	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
KYE74_RS05030	COG0561	phosphatase activity
KYE74_RS05035	COG0436	Aminotransferase
KYE74_RS05045	COG3201	nicotinamide mononucleotide transporter
KYE74_RS05060	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
KYE74_RS05135	COG1716	ATPase activity
KYE74_RS05200	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KYE74_RS05225	COG0045	succinate-CoA ligase (ADP-forming) activity
KYE74_RS05260	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KYE74_RS05300	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
KYE74_RS05315	COG0133	tryptophan synthase activity
KYE74_RS05370	COG1022	Amp-dependent synthetase and ligase
KYE74_RS05390	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
KYE74_RS05495	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYE74_RS05500	COG0497	DNA recombination
KYE74_RS05510	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
KYE74_RS05515	COG0569	domain protein
KYE74_RS05610	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
KYE74_RS05620	COG1611	Belongs to the LOG family
KYE74_RS05630	COG1573	uracil-dna glycosylase
KYE74_RS05670	COG1122	ATPase activity
KYE74_RS05675	COG4721	ABC-type cobalt transport system, permease component
KYE74_RS05705	COG1122	ATPase activity
KYE74_RS05710	COG0436	Aminotransferase
KYE74_RS05725	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
KYE74_RS05755	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
KYE74_RS05840	COG0667	Aldo Keto reductase
KYE74_RS05880	COG1882	Formate acetyltransferase
KYE74_RS05895	COG1473	amidohydrolase
KYE74_RS05900	COG2011	ABC-type metal ion transport system permease component
KYE74_RS05910	COG1464	Belongs to the NlpA lipoprotein family
KYE74_RS05930	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
KYE74_RS05935	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
KYE74_RS05960	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
KYE74_RS05965	COG1201	RNA secondary structure unwinding
KYE74_RS05970	COG3655	Transcriptional regulator
KYE74_RS05990	COG0187	DNA topoisomerase II activity
KYE74_RS05995	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
KYE74_RS06005	COG0142	geranyltranstransferase activity
KYE74_RS06025	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
KYE74_RS06035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
KYE74_RS06060	COG1396	sequence-specific DNA binding
KYE74_RS06065	COG1546	Belongs to the CinA family
KYE74_RS06065	COG1058	Belongs to the CinA family
KYE74_RS06070	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
KYE74_RS06090	COG2357	RelA SpoT domain protein
KYE74_RS06100	COG0670	Belongs to the BI1 family
KYE74_RS06115	COG2197	response regulator
KYE74_RS06125	COG2197	response regulator
KYE74_RS06130	COG4585	Histidine kinase
KYE74_RS06135	COG1131	(ABC) transporter
KYE74_RS06150	COG3292	Two component regulator propeller
KYE74_RS06150	COG0745	RESPONSE REGULATOR receiver
KYE74_RS06150	COG2205	protein histidine kinase activity
KYE74_RS06155	COG0110	maltose O-acetyltransferase activity
KYE74_RS06160	COG0534	Mate efflux family protein
KYE74_RS06165	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
KYE74_RS06195	COG0708	Exodeoxyribonuclease III
KYE74_RS06205	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
KYE74_RS06210	COG0601	transmembrane transport
KYE74_RS06215	COG4166	transmembrane transport
KYE74_RS06220	COG4166	transmembrane transport
KYE74_RS06235	COG0287	Prephenate dehydrogenase
KYE74_RS06250	COG1217	gtp-binding protein TYPA
KYE74_RS06255	COG0477	Major facilitator Superfamily
KYE74_RS06285	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
KYE74_RS06300	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
KYE74_RS06320	COG1595	DNA-templated transcription, initiation
KYE74_RS06335	COG0285	dihydrofolate synthase activity
KYE74_RS06340	COG0006	proline dipeptidase activity
KYE74_RS06360	COG0601	transmembrane transport
KYE74_RS06375	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYE74_RS06425	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
KYE74_RS06435	COG0768	penicillin binding
KYE74_RS06460	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
KYE74_RS06490	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
KYE74_RS06495	COG2813	Specifically methylates the guanine in position
KYE74_RS06500	COG1643	Atp-dependent helicase
KYE74_RS06520	COG1136	(ABC) transporter
KYE74_RS06525	COG2814	Major facilitator Superfamily
KYE74_RS06575	COG0587	DNA-directed DNA polymerase activity
KYE74_RS06605	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
KYE74_RS06635	COG1989	Cleaves type-4 fimbrial leader sequence and methylates the N-terminal (generally Phe) residue
KYE74_RS06645	COG1459	type II secretion system
KYE74_RS06650	COG4969	Belongs to the N-Me-Phe pilin family
KYE74_RS06665	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
KYE74_RS06690	COG0351	phosphomethylpyrimidine kinase
KYE74_RS06715	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
KYE74_RS06770	COG3480	Lon protease (S16) C-terminal proteolytic domain
KYE74_RS06795	COG0613	PHP domain protein
KYE74_RS06805	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
KYE74_RS06820	COG0747	negative chemotaxis
KYE74_RS06850	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
KYE74_RS06855	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
KYE74_RS06860	COG1518	maintenance of DNA repeat elements
KYE74_RS06900	COG1609	Transcriptional regulator
KYE74_RS06910	COG1132	(ABC) transporter
KYE74_RS06915	COG1132	(ABC) transporter
KYE74_RS06935	COG1929	Belongs to the glycerate kinase type-1 family
KYE74_RS06940	COG2211	Major facilitator Superfamily
KYE74_RS06945	COG3250	beta-galactosidase activity
KYE74_RS06955	COG1609	Transcriptional regulator
KYE74_RS06970	COG0477	Major facilitator Superfamily
KYE74_RS06980	COG1309	transcriptional regulator
KYE74_RS06990	COG3507	Belongs to the glycosyl hydrolase 43 family
KYE74_RS07000	COG2211	Major facilitator Superfamily
KYE74_RS07015	COG1309	transcriptional regulator
KYE74_RS07030	COG0602	queuosine metabolic process
KYE74_RS07035	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
KYE74_RS07035	COG1328	CTP reductase activity
KYE74_RS07040	COG1570	exodeoxyribonuclease VII activity
KYE74_RS07045	COG1722	exodeoxyribonuclease VII activity
KYE74_RS07080	COG0248	Ppx GppA phosphatase
KYE74_RS07085	COG0436	Aminotransferase
KYE74_RS07100	COG0210	DNA helicase
KYE74_RS07160	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
KYE74_RS07175	COG1937	Protein conserved in bacteria
KYE74_RS07200	COG2815	serine threonine protein kinase
KYE74_RS07200	COG0515	serine threonine protein kinase
KYE74_RS07210	COG0714	Associated with various cellular activities
KYE74_RS07225	COG0631	protein serine/threonine phosphatase activity
KYE74_RS07255	COG1194	a g-specific adenine glycosylase
KYE74_RS07260	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
KYE74_RS07275	COG1621	beta-fructofuranosidase activity
KYE74_RS07290	COG0395	ABC-type sugar transport system, permease component
KYE74_RS07295	COG4209	transmembrane transport
KYE74_RS07305	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
KYE74_RS07315	COG1349	DNA-binding transcription factor activity
KYE74_RS07320	COG0167	dihydroorotate dehydrogenase activity
KYE74_RS07325	COG1902	pentaerythritol trinitrate reductase activity
KYE74_RS07330	COG4499	WXG100 protein secretion system (Wss), protein YukC
KYE74_RS07330	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
KYE74_RS07340	COG0095	Lipoate-protein ligase
KYE74_RS07355	COG1770	oligopeptidase
KYE74_RS07385	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
KYE74_RS07400	COG0366	Alpha amylase catalytic
KYE74_RS07420	COG0438	transferase activity, transferring glycosyl groups
KYE74_RS07435	COG1216	Glycosyl transferase, family 2
KYE74_RS07445	COG0366	Alpha amylase catalytic
KYE74_RS07465	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
KYE74_RS07470	COG0489	protein tyrosine kinase activity
KYE74_RS07475	COG1501	Belongs to the glycosyl hydrolase 31 family
KYE74_RS07480	COG0395	ABC-type sugar transport system, permease component
KYE74_RS07485	COG1175	transmembrane transport
KYE74_RS07495	COG1609	Transcriptional regulator
KYE74_RS07500	COG5290	Psort location Cytoplasmic, score
KYE74_RS07580	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
KYE74_RS07620	COG0463	Glycosyl transferase, family 2
KYE74_RS07620	COG1887	Glycosyl glycerophosphate transferases involved in teichoic acid biosynthesis TagF TagB EpsJ RodC
KYE74_RS07640	COG1442	glycosyl transferase family 8
KYE74_RS07650	COG0438	transferase activity, transferring glycosyl groups
KYE74_RS07655	COG0438	transferase activity, transferring glycosyl groups
KYE74_RS07660	COG0438	transferase activity, transferring glycosyl groups
KYE74_RS07675	COG1216	Glycosyl transferase, family 2
KYE74_RS07675	COG1442	glycosyl transferase family 8
KYE74_RS07680	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
KYE74_RS07740	COG1609	Transcriptional regulator
KYE74_RS07770	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
KYE74_RS07790	COG2814	Major facilitator Superfamily
KYE74_RS07795	COG3300	MHYT domain
KYE74_RS07795	COG5001	Diguanylate cyclase
KYE74_RS07805	COG0656	L-ascorbic acid biosynthetic process
KYE74_RS07815	COG1609	Transcriptional regulator
KYE74_RS07825	COG0395	ABC-type sugar transport system, permease component
KYE74_RS07830	COG1175	transmembrane transport
KYE74_RS07835	COG1653	transport
KYE74_RS07850	COG4988	ABC transporter
KYE74_RS07880	COG1609	Transcriptional regulator
KYE74_RS07890	COG0083	homoserine kinase activity
KYE74_RS07895	COG0460	homoserine dehydrogenase
KYE74_RS07910	COG0833	amino acid
KYE74_RS07915	COG0251	oxidation-reduction process
KYE74_RS07945	COG0545	Peptidyl-prolyl cis-trans isomerase
KYE74_RS07955	COG0355	proton-transporting ATP synthase activity, rotational mechanism
KYE74_RS07990	COG0356	it plays a direct role in the translocation of protons across the membrane
KYE74_RS08010	COG0679	Auxin Efflux Carrier
KYE74_RS08015	COG0028	Belongs to the TPP enzyme family
KYE74_RS08030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
KYE74_RS08045	COG0745	RESPONSE REGULATOR receiver
KYE74_RS08055	COG0747	negative chemotaxis
KYE74_RS08075	COG1522	sequence-specific DNA binding
KYE74_RS08130	COG1322	Protein conserved in bacteria
KYE74_RS08145	COG0179	Fumarylacetoacetate (FAA) hydrolase
KYE74_RS08150	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
KYE74_RS08175	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
KYE74_RS08225	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
KYE74_RS08260	COG1088	dTDP-glucose 4,6-dehydratase activity
KYE74_RS08270	COG1368	sulfuric ester hydrolase activity
KYE74_RS08280	COG1216	Glycosyl transferase, family 2
KYE74_RS08320	COG3475	LICD family
KYE74_RS08325	COG1216	Glycosyl transferase, family 2
KYE74_RS08345	COG0463	Glycosyl transferase, family 2
KYE74_RS08420	COG1136	(ABC) transporter
KYE74_RS08440	COG0084	hydrolase, TatD family'
KYE74_RS08470	COG1132	(ABC) transporter
KYE74_RS08475	COG1132	(ABC) transporter
KYE74_RS08500	COG0395	ABC-type sugar transport system, permease component
KYE74_RS08505	COG1609	Transcriptional regulator
KYE74_RS08515	COG3469	chitinase activity
KYE74_RS08520	COG2199	diguanylate cyclase activity
KYE74_RS08525	COG1609	Transcriptional regulator
KYE74_RS08545	COG1940	carbohydrate kinase activity
KYE74_RS08550	COG0395	ABC-type sugar transport system, permease component
KYE74_RS08555	COG1175	transmembrane transport
KYE74_RS08575	COG3250	beta-galactosidase activity
KYE74_RS08615	COG0586	Pfam SNARE associated Golgi protein
KYE74_RS08625	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
KYE74_RS08635	COG0789	Transcriptional regulator
KYE74_RS08640	COG0484	heat shock protein binding
KYE74_RS08665	COG0730	response to heat
KYE74_RS08670	COG1609	Transcriptional regulator
KYE74_RS08680	COG0546	phosphoglycolate phosphatase activity
KYE74_RS08700	COG3340	Belongs to the peptidase S51 family
KYE74_RS08720	COG1609	Transcriptional regulator
KYE74_RS08725	COG1609	Transcriptional regulator
KYE74_RS08735	COG0366	Alpha amylase catalytic
KYE74_RS08745	COG0588	phosphoglycerate mutase activity
KYE74_RS08785	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
KYE74_RS08790	COG3250	beta-galactosidase activity
KYE74_RS08825	COG3842	ATPase activity
KYE74_RS08830	COG2204	response regulator
KYE74_RS08890	COG1472	Belongs to the glycosyl hydrolase 3 family
KYE74_RS08915	COG0577	efflux transmembrane transporter activity
KYE74_RS08925	COG3250	beta-galactosidase activity
KYE74_RS08930	COG1609	Transcriptional regulator
KYE74_RS08940	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
KYE74_RS08950	COG1028	Short-chain dehydrogenase reductase Sdr
KYE74_RS08955	COG4948	Mandelate Racemase Muconate Lactonizing
KYE74_RS08965	COG0395	ABC-type sugar transport system, permease component
KYE74_RS08970	COG1175	transmembrane transport
KYE74_RS08990	COG1609	Transcriptional regulator
KYE74_RS09000	COG0366	Alpha amylase catalytic
KYE74_RS09005	COG1175	transmembrane transport
KYE74_RS09010	COG0395	ABC-type sugar transport system, permease component
KYE74_RS09055	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
KYE74_RS09060	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
KYE74_RS09065	COG0366	Alpha amylase catalytic
KYE74_RS09070	COG0395	ABC-type sugar transport system, permease component
KYE74_RS09075	COG1175	transmembrane transport
KYE74_RS09080	COG1653	transport
KYE74_RS09095	COG0037	tRNA processing
KYE74_RS09095	COG0590	tRNA wobble adenosine to inosine editing
KYE74_RS09100	COG0025	NhaP-type Na H and K H
KYE74_RS09150	COG3583	domain protein
KYE74_RS09170	COG0617	tRNA 3'-terminal CCA addition
KYE74_RS09195	COG4502	5' nucleotidase, deoxy (Pyrimidine), cytosolic type C protein (NT5C)
KYE74_RS09200	COG0492	ferredoxin-NADP+ reductase activity
KYE74_RS09210	COG1192	Involved in chromosome partitioning
KYE74_RS09220	COG1847	R3H domain protein
KYE74_RS09330	COG2814	Major facilitator Superfamily