locus-tag	class	description
BP20092_RS00105	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BP20092_RS00110	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BP20092_RS00125	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BP20092_RS00125	COG1754	DNA topoisomerase type I activity
BP20092_RS00140	COG1260	myo-inositol-1-phosphate synthase
BP20092_RS00145	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BP20092_RS00165	COG0527	aspartate kinase activity
BP20092_RS00225	COG0406	alpha-ribazole phosphatase activity
BP20092_RS00225	COG0494	nUDIX hydrolase
BP20092_RS00240	COG2261	transglycosylase associated protein
BP20092_RS00245	COG2261	transglycosylase associated protein
BP20092_RS00255	COG0584	glycerophosphoryl diester phosphodiesterase
BP20092_RS00275	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BP20092_RS00280	COG0305	Participates in initiation and elongation during chromosome replication
BP20092_RS00285	COG1573	uracil-dna glycosylase
BP20092_RS00290	COG1573	uracil-dna glycosylase
BP20092_RS00295	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BP20092_RS00315	COG1309	transcriptional regulator
BP20092_RS00330	COG1129	ABC transporter
BP20092_RS00365	COG0671	phosphoesterase, PA-phosphatase related
BP20092_RS00375	COG0346	lactoylglutathione lyase activity
BP20092_RS00395	COG1846	Transcriptional regulator
BP20092_RS00400	COG1113	amino acid transport
BP20092_RS00410	COG1136	(ABC) transporter
BP20092_RS00410	COG4591	ABC-type transport system involved in lipoprotein release permease component
BP20092_RS00420	COG1113	amino acid transport
BP20092_RS00445	COG1609	Transcriptional regulator
BP20092_RS00455	COG1401	restriction endodeoxyribonuclease activity
BP20092_RS00490	COG2226	methyltransferase
BP20092_RS00510	COG0477	Major facilitator Superfamily
BP20092_RS00530	COG2315	Protein conserved in bacteria
BP20092_RS00555	COG0191	fructose-bisphosphate aldolase activity
BP20092_RS00580	COG0350	Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction the enzyme is irreversibly inactivated
BP20092_RS00595	COG2814	Major facilitator Superfamily
BP20092_RS00620	COG0493	'glutamate synthase
BP20092_RS00640	COG0343	queuine tRNA-ribosyltransferase activity
BP20092_RS00655	COG2226	methyltransferase
BP20092_RS00665	COG0697	spore germination
BP20092_RS00700	COG0768	penicillin binding
BP20092_RS00720	COG3764	Sortase (surface protein transpeptidase)
BP20092_RS00725	COG3879	Bacterial protein of unknown function (DUF881)
BP20092_RS00755	COG0058	SHG alpha-glucan phosphorylase activity
BP20092_RS00770	COG0180	Tryptophanyl-tRNA synthetase
BP20092_RS00780	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BP20092_RS00820	COG4214	carbohydrate transport
BP20092_RS00830	COG1609	Transcriptional regulator
BP20092_RS00835	COG0288	reversible hydration of carbon dioxide
BP20092_RS00845	COG1253	flavin adenine dinucleotide binding
BP20092_RS00850	COG0783	Belongs to the Dps family
BP20092_RS00935	COG3231	kanamycin kinase activity
BP20092_RS00975	COG2226	methyltransferase
BP20092_RS00980	COG0596	Alpha beta hydrolase
BP20092_RS01060	COG1970	mechanosensitive ion channel activity
BP20092_RS01070	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
BP20092_RS01075	COG1272	protein, Hemolysin III
BP20092_RS01095	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BP20092_RS01100	COG0187	DNA topoisomerase II activity
BP20092_RS01115	COG0592	DNA-directed DNA polymerase activity
BP20092_RS01145	COG1847	R3H domain protein
BP20092_RS01155	COG1192	Involved in chromosome partitioning
BP20092_RS01170	COG0492	ferredoxin-NADP+ reductase activity
BP20092_RS01180	COG1957	nucleoside hydrolase
BP20092_RS01210	COG0617	tRNA 3'-terminal CCA addition
BP20092_RS01230	COG3583	domain protein
BP20092_RS01250	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BP20092_RS01255	COG3842	ATPase activity
BP20092_RS01265	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BP20092_RS01270	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
BP20092_RS01275	COG0596	Alpha beta hydrolase
BP20092_RS01290	COG0025	NhaP-type Na H and K H
BP20092_RS01295	COG0590	tRNA wobble adenosine to inosine editing
BP20092_RS01295	COG0037	tRNA processing
BP20092_RS01310	COG1653	transport
BP20092_RS01315	COG1175	transmembrane transport
BP20092_RS01320	COG0395	ABC-type sugar transport system, permease component
BP20092_RS01335	COG0366	Alpha amylase catalytic
BP20092_RS01350	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
BP20092_RS01355	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BP20092_RS01375	COG0477	Major facilitator Superfamily
BP20092_RS01380	COG3177	Filamentation induced by cAMP protein fic
BP20092_RS01430	COG0588	phosphoglycerate mutase activity
BP20092_RS01435	COG0366	Alpha amylase catalytic
BP20092_RS01440	COG2182	Extracellular solute-binding protein
BP20092_RS01445	COG1609	Transcriptional regulator
BP20092_RS01530	COG1175	transmembrane transport
BP20092_RS01535	COG3833	ABC-type maltose transport systems, permease component
BP20092_RS01540	COG1523	belongs to the glycosyl hydrolase 13 family
BP20092_RS01545	COG1011	Hydrolase
BP20092_RS01555	COG1609	Transcriptional regulator
BP20092_RS01570	COG0484	heat shock protein binding
BP20092_RS01575	COG0789	Transcriptional regulator
BP20092_RS01580	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BP20092_RS01585	COG1472	Belongs to the glycosyl hydrolase 3 family
BP20092_RS01600	COG1609	Transcriptional regulator
BP20092_RS01615	COG0586	Pfam SNARE associated Golgi protein
BP20092_RS01660	COG1132	(ABC) transporter
BP20092_RS01675	COG0084	hydrolase, TatD family'
BP20092_RS01705	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BP20092_RS01720	COG1216	Glycosyl transferase, family 2
BP20092_RS01740	COG1216	Glycosyl transferase, family 2
BP20092_RS01770	COG1216	Glycosyl transferase, family 2
BP20092_RS01775	COG1368	sulfuric ester hydrolase activity
BP20092_RS01800	COG3594	Acyltransferase
BP20092_RS01870	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BP20092_RS01885	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
BP20092_RS01895	COG2826	transposase and inactivated derivatives, IS30 family
BP20092_RS01915	COG0179	Fumarylacetoacetate (FAA) hydrolase
BP20092_RS01925	COG2217	Heavy metal translocating P-type atpase
BP20092_RS01945	COG1131	(ABC) transporter
BP20092_RS01990	COG1522	sequence-specific DNA binding
BP20092_RS02020	COG0745	RESPONSE REGULATOR receiver
BP20092_RS02030	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BP20092_RS02050	COG0028	Belongs to the TPP enzyme family
BP20092_RS02055	COG0679	Auxin Efflux Carrier
BP20092_RS02075	COG0356	it plays a direct role in the translocation of protons across the membrane
BP20092_RS02110	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BP20092_RS02120	COG0545	Peptidyl-prolyl cis-trans isomerase
BP20092_RS02150	COG0251	oxidation-reduction process
BP20092_RS02165	COG0460	homoserine dehydrogenase
BP20092_RS02170	COG0083	homoserine kinase activity
BP20092_RS02175	COG0489	protein tyrosine kinase activity
BP20092_RS02185	COG0366	Alpha amylase catalytic
BP20092_RS02190	COG0366	Alpha amylase catalytic
BP20092_RS02195	COG0366	Alpha amylase catalytic
BP20092_RS02200	COG1216	Glycosyl transferase, family 2
BP20092_RS02205	COG5039	Polysaccharide pyruvyl transferase
BP20092_RS02220	COG0463	Glycosyl transferase, family 2
BP20092_RS02270	COG1216	Glycosyl transferase, family 2
BP20092_RS02275	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BP20092_RS02295	COG1132	(ABC) transporter
BP20092_RS02340	COG2814	Major facilitator Superfamily
BP20092_RS02350	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BP20092_RS02375	COG1216	Glycosyl transferase, family 2
BP20092_RS02405	COG1088	dTDP-glucose 4,6-dehydratase activity
BP20092_RS02435	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BP20092_RS02445	COG2267	carboxylic ester hydrolase activity
BP20092_RS02475	COG2314	TM2 domain
BP20092_RS02480	COG0095	Lipoate-protein ligase
BP20092_RS02485	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BP20092_RS02490	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BP20092_RS02490	COG4499	WXG100 protein secretion system (Wss), protein YukC
BP20092_RS02495	COG1902	pentaerythritol trinitrate reductase activity
BP20092_RS02500	COG0167	dihydroorotate dehydrogenase activity
BP20092_RS02505	COG0463	Glycosyl transferase, family 2
BP20092_RS02510	COG1349	DNA-binding transcription factor activity
BP20092_RS02520	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
BP20092_RS02540	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BP20092_RS02545	COG1194	a g-specific adenine glycosylase
BP20092_RS02590	COG0714	Associated with various cellular activities
BP20092_RS02600	COG0515	serine threonine protein kinase
BP20092_RS02600	COG2815	serine threonine protein kinase
BP20092_RS02610	COG0210	DNA helicase
BP20092_RS02635	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
BP20092_RS02660	COG3579	cysteine-type endopeptidase activity
BP20092_RS02665	COG0531	amino acid
BP20092_RS02685	COG0436	Aminotransferase
BP20092_RS02690	COG0248	Ppx GppA phosphatase
BP20092_RS02710	COG1722	exodeoxyribonuclease VII activity
BP20092_RS02715	COG1570	exodeoxyribonuclease VII activity
BP20092_RS02720	COG1328	CTP reductase activity
BP20092_RS02720	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BP20092_RS02725	COG0602	queuosine metabolic process
BP20092_RS02735	COG1924	4 iron, 4 sulfur cluster binding
BP20092_RS02805	COG1132	(ABC) transporter
BP20092_RS02810	COG1132	(ABC) transporter
BP20092_RS02835	COG2365	Tyrosine phosphatase family
BP20092_RS02860	COG1842	Phage shock protein A
BP20092_RS02870	COG4166	transmembrane transport
BP20092_RS02925	COG2176	DNA-directed DNA polymerase activity
BP20092_RS02935	COG0531	amino acid
BP20092_RS02940	COG1893	Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid
BP20092_RS02950	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BP20092_RS02955	COG2011	ABC-type metal ion transport system permease component
BP20092_RS02960	COG0436	Aminotransferase
BP20092_RS02965	COG0765	amino acid transport
BP20092_RS02970	COG0765	amino acid transport
BP20092_RS02975	COG1126	abc transporter atp-binding protein
BP20092_RS03000	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BP20092_RS03035	COG3480	Lon protease (S16) C-terminal proteolytic domain
BP20092_RS03095	COG1957	nucleoside hydrolase
BP20092_RS03105	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BP20092_RS03115	COG2826	transposase and inactivated derivatives, IS30 family
BP20092_RS03185	COG0587	DNA-directed DNA polymerase activity
BP20092_RS03225	COG0174	glutamine synthetase
BP20092_RS03235	COG1643	Atp-dependent helicase
BP20092_RS03240	COG2813	Specifically methylates the guanine in position
BP20092_RS03245	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BP20092_RS03265	COG3858	chitin binding
BP20092_RS03265	COG1388	LysM domain
BP20092_RS03275	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BP20092_RS03300	COG0768	penicillin binding
BP20092_RS03350	COG3250	beta-galactosidase activity
BP20092_RS03355	COG1609	Transcriptional regulator
BP20092_RS03410	COG0601	transmembrane transport
BP20092_RS03435	COG0006	proline dipeptidase activity
BP20092_RS03460	COG0285	dihydrofolate synthase activity
BP20092_RS03490	COG2017	converts alpha-aldose to the beta-anomer
BP20092_RS03500	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BP20092_RS03515	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BP20092_RS03545	COG0477	Major facilitator Superfamily
BP20092_RS03550	COG1217	gtp-binding protein TYPA
BP20092_RS03565	COG0287	Prephenate dehydrogenase
BP20092_RS03575	COG1929	Belongs to the glycerate kinase type-1 family
BP20092_RS03580	COG0577	efflux transmembrane transporter activity
BP20092_RS03585	COG1136	(ABC) transporter
BP20092_RS03585	COG4591	ABC-type transport system involved in lipoprotein release permease component
BP20092_RS03595	COG4166	transmembrane transport
BP20092_RS03600	COG0601	transmembrane transport
BP20092_RS03605	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP20092_RS03620	COG0708	Exodeoxyribonuclease III
BP20092_RS03650	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BP20092_RS03660	COG1335	isochorismatase
BP20092_RS03670	COG2826	transposase and inactivated derivatives, IS30 family
BP20092_RS03685	COG1131	(ABC) transporter
BP20092_RS03690	COG4585	Histidine kinase
BP20092_RS03695	COG2197	response regulator
BP20092_RS03700	COG0670	Belongs to the BI1 family
BP20092_RS03705	COG2357	RelA SpoT domain protein
BP20092_RS03725	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BP20092_RS03730	COG1058	Belongs to the CinA family
BP20092_RS03730	COG1546	Belongs to the CinA family
BP20092_RS03735	COG1396	sequence-specific DNA binding
BP20092_RS03760	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BP20092_RS03770	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BP20092_RS03790	COG0142	geranyltranstransferase activity
BP20092_RS03800	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BP20092_RS03805	COG0187	DNA topoisomerase II activity
BP20092_RS03830	COG1201	RNA secondary structure unwinding
BP20092_RS03835	COG4975	Glucose uptake
BP20092_RS03840	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BP20092_RS03865	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
BP20092_RS03870	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
BP20092_RS03880	COG1464	Belongs to the NlpA lipoprotein family
BP20092_RS03890	COG2011	ABC-type metal ion transport system permease component
BP20092_RS03895	COG1473	amidohydrolase
BP20092_RS03900	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BP20092_RS03900	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BP20092_RS03910	COG1882	Formate acetyltransferase
BP20092_RS03915	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
BP20092_RS03970	COG1611	Belongs to the LOG family
BP20092_RS03980	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BP20092_RS03985	COG1053	succinate dehydrogenase
BP20092_RS03990	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BP20092_RS03990	COG0758	DNA mediated transformation
BP20092_RS04005	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BP20092_RS04010	COG2873	o-acetylhomoserine
BP20092_RS04015	COG1122	ATPase activity
BP20092_RS04025	COG1136	(ABC) transporter
BP20092_RS04025	COG0577	efflux transmembrane transporter activity
BP20092_RS04035	COG2197	response regulator
BP20092_RS04040	COG4585	Histidine kinase
BP20092_RS04050	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
BP20092_RS04055	COG0012	GTP binding
BP20092_RS04075	COG2233	PERMEase
BP20092_RS04080	COG0513	Belongs to the DEAD box helicase family
BP20092_RS04085	COG4221	oxidoreductase activity
BP20092_RS04110	COG0362	Catalyzes the oxidative decarboxylation of 6- phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH
BP20092_RS04115	COG0363	glucosamine-6-phosphate deaminase activity
BP20092_RS04135	COG1918	ferrous iron import across plasma membrane
BP20092_RS04135	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BP20092_RS04145	COG1027	Aspartate ammonia-lyase
BP20092_RS04170	COG4552	Acetyltransferase involved in intracellular survival and related
BP20092_RS04185	COG1966	Carbon starvation protein
BP20092_RS04250	COG1760	l-serine dehydratase
BP20092_RS04260	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BP20092_RS04280	COG1674	ftsk spoiiie
BP20092_RS04285	COG1316	TRANSCRIPTIONal
BP20092_RS04290	COG1316	TRANSCRIPTIONal
BP20092_RS04320	COG2205	protein histidine kinase activity
BP20092_RS04325	COG0745	RESPONSE REGULATOR receiver
BP20092_RS04335	COG1329	Transcriptional regulator
BP20092_RS04350	COG1121	(ABC) transporter
BP20092_RS04365	COG0539	negative regulation of cytoplasmic translation
BP20092_RS04370	COG0237	dephospho-CoA kinase activity
BP20092_RS04385	COG0469	pyruvate kinase activity
BP20092_RS04395	COG3655	Transcriptional regulator
BP20092_RS04415	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
BP20092_RS04445	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BP20092_RS04450	COG0857	belongs to the CobB CobQ family
BP20092_RS04450	COG0280	phosphate acetyltransferase
BP20092_RS04485	COG1816	Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism
BP20092_RS04490	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
BP20092_RS04525	COG1950	PFAM Membrane protein of
BP20092_RS04530	COG0406	alpha-ribazole phosphatase activity
BP20092_RS04575	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BP20092_RS04620	COG1136	(ABC) transporter
BP20092_RS04620	COG0577	efflux transmembrane transporter activity
BP20092_RS04640	COG1376	ErfK ybiS ycfS ynhG family protein
BP20092_RS04655	COG0396	ATPase activity
BP20092_RS04670	COG2151	metal-sulfur cluster biosynthetic enzyme
BP20092_RS04680	COG1385	rRNA (uridine-N3-)-methyltransferase activity
BP20092_RS04690	COG0537	adenosine 5'-monophosphoramidase activity
BP20092_RS04720	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
BP20092_RS04745	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
BP20092_RS04750	COG2860	membrane
BP20092_RS04770	COG0067	glutamate synthase
BP20092_RS04770	COG0069	glutamate synthase activity
BP20092_RS04770	COG0070	glutamate synthase
BP20092_RS04790	COG1119	ATPase activity
BP20092_RS04810	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BP20092_RS04830	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BP20092_RS04835	COG0284	orotidine-5'-phosphate decarboxylase activity
BP20092_RS04840	COG0543	2 iron, 2 sulfur cluster binding
BP20092_RS04845	COG0167	dihydroorotate dehydrogenase activity
BP20092_RS04885	COG0583	DNA-binding transcription factor activity
BP20092_RS04895	COG0492	ferredoxin-NADP+ reductase activity
BP20092_RS04900	COG0450	alkyl hydroperoxide reductase
BP20092_RS04925	COG0488	(ABC) transporter
BP20092_RS04950	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BP20092_RS04975	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BP20092_RS04980	COG0561	phosphatase activity
BP20092_RS04985	COG0436	Aminotransferase
BP20092_RS04995	COG0436	Aminotransferase
BP20092_RS05000	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BP20092_RS05065	COG1131	(ABC) transporter
BP20092_RS05100	COG0488	(ABC) transporter
BP20092_RS05120	COG1560	Kdo2-lipid A biosynthetic process
BP20092_RS05125	COG0438	transferase activity, transferring glycosyl groups
BP20092_RS05150	COG1862	Preprotein translocase
BP20092_RS05160	COG0045	succinate-CoA ligase (ADP-forming) activity
BP20092_RS05185	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
BP20092_RS05245	COG1716	ATPase activity
BP20092_RS05265	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BP20092_RS05280	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BP20092_RS05295	COG0133	tryptophan synthase activity
BP20092_RS05340	COG0575	Belongs to the CDS family
BP20092_RS05370	COG1022	Amp-dependent synthetase and ligase
BP20092_RS05380	COG0516	GMP reductase activity
BP20092_RS05435	COG0802	atpase or kinase
BP20092_RS05450	COG1596	polysaccharide export
BP20092_RS05450	COG1555	photosystem II stabilization
BP20092_RS05465	COG0598	Magnesium transport protein CorA
BP20092_RS05470	COG0406	alpha-ribazole phosphatase activity
BP20092_RS05495	COG0588	phosphoglycerate mutase activity
BP20092_RS05500	COG0799	negative regulation of ribosome biogenesis
BP20092_RS05520	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BP20092_RS05545	COG0497	DNA recombination
BP20092_RS05555	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BP20092_RS05560	COG0569	domain protein
BP20092_RS05645	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BP20092_RS05650	COG0577	efflux transmembrane transporter activity
BP20092_RS05655	COG1136	(ABC) transporter
BP20092_RS05665	COG4721	ABC-type cobalt transport system, permease component
BP20092_RS05675	COG1136	(ABC) transporter
BP20092_RS05700	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP20092_RS05780	COG0489	protein tyrosine kinase activity
BP20092_RS05780	COG2151	metal-sulfur cluster biosynthetic enzyme
BP20092_RS05815	COG1122	ATPase activity
BP20092_RS05840	COG0656	L-ascorbic acid biosynthetic process
BP20092_RS05850	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
BP20092_RS05855	COG3304	Inner membrane component domain
BP20092_RS05880	COG1022	Amp-dependent synthetase and ligase
BP20092_RS05885	COG2814	Major facilitator Superfamily
BP20092_RS05900	COG2326	polyphosphate kinase activity
BP20092_RS05905	COG0765	amino acid transport
BP20092_RS05910	COG0765	amino acid transport
BP20092_RS05915	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP20092_RS05920	COG1126	abc transporter atp-binding protein
BP20092_RS05940	COG1196	nuclear chromosome segregation
BP20092_RS05950	COG0589	response to stress
BP20092_RS05965	COG1278	Cold shock
BP20092_RS05970	COG2205	protein histidine kinase activity
BP20092_RS05975	COG0745	RESPONSE REGULATOR receiver
BP20092_RS05995	COG1278	Cold shock
BP20092_RS06010	COG0714	Associated with various cellular activities
BP20092_RS06050	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BP20092_RS06085	COG1222	aaa ATPase
BP20092_RS06090	COG0586	Pfam SNARE associated Golgi protein
BP20092_RS06095	COG0560	Phosphoserine phosphatase
BP20092_RS06105	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
BP20092_RS06110	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BP20092_RS06135	COG0284	orotidine-5'-phosphate decarboxylase activity
BP20092_RS06215	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BP20092_RS06250	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BP20092_RS06265	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BP20092_RS06280	COG0151	Belongs to the GarS family
BP20092_RS06285	COG0477	Major facilitator Superfamily
BP20092_RS06300	COG0627	Serine hydrolase involved in the detoxification of formaldehyde
BP20092_RS06305	COG2898	Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), a major component of the bacterial membrane with a positive net charge. LPG synthesis contributes to bacterial virulence as it is involved in the resistance mechanism against cationic antimicrobial peptides (CAMP) produces by the host's immune system (defensins, cathelicidins) and by the competing microorganisms
BP20092_RS06315	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BP20092_RS06320	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
BP20092_RS06330	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BP20092_RS06355	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
BP20092_RS06370	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BP20092_RS06385	COG0371	Dehydrogenase
BP20092_RS06395	COG0514	ATP-dependent DNA helicase (RecQ)
BP20092_RS06415	COG4608	Belongs to the ABC transporter superfamily
BP20092_RS06420	COG0444	Belongs to the ABC transporter superfamily
BP20092_RS06425	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
BP20092_RS06430	COG0601	transmembrane transport
BP20092_RS06435	COG4166	transmembrane transport
BP20092_RS06445	COG1653	transport
BP20092_RS06455	COG0564	pseudouridine synthase activity
BP20092_RS06460	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BP20092_RS06475	COG0765	amino acid transport
BP20092_RS06480	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BP20092_RS06545	COG1971	Probably functions as a manganese efflux pump
BP20092_RS06570	COG3942	CHAP domain
BP20092_RS06570	COG1388	LysM domain
BP20092_RS06575	COG2177	Part of the ABC transporter FtsEX involved in
BP20092_RS06580	COG2884	Cell division ATP-binding protein ftsE
BP20092_RS06585	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
BP20092_RS06600	COG0372	Belongs to the citrate synthase family
BP20092_RS06615	COG3590	peptidase
BP20092_RS06635	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BP20092_RS06640	COG0561	phosphatase activity
BP20092_RS06665	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BP20092_RS06670	COG0009	L-threonylcarbamoyladenylate synthase
BP20092_RS06705	COG1940	carbohydrate kinase activity
BP20092_RS06710	COG1070	Carbohydrate kinase
BP20092_RS06720	COG2272	Belongs to the type-B carboxylesterase lipase family
BP20092_RS06730	COG3507	Belongs to the glycosyl hydrolase 43 family
BP20092_RS06740	COG1175	transmembrane transport
BP20092_RS06750	COG1609	Transcriptional regulator
BP20092_RS06755	COG3507	Belongs to the glycosyl hydrolase 43 family
BP20092_RS06765	COG2249	NAD(P)H dehydrogenase (quinone) activity
BP20092_RS06785	COG2873	o-acetylhomoserine
BP20092_RS06805	COG1946	Acyl-CoA thioesterase
BP20092_RS06820	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BP20092_RS06850	COG1215	transferase activity, transferring glycosyl groups
BP20092_RS06855	COG0628	permease
BP20092_RS06860	COG1216	Glycosyl transferase, family 2
BP20092_RS06865	COG0789	Transcriptional regulator
BP20092_RS06900	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BP20092_RS06905	COG0531	amino acid
BP20092_RS06915	COG1454	alcohol dehydrogenase
BP20092_RS06935	COG1397	ADP-ribosylglycohydrolase
BP20092_RS06965	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
BP20092_RS06975	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BP20092_RS06980	COG4721	ABC-type cobalt transport system, permease component
BP20092_RS06985	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BP20092_RS06990	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
BP20092_RS07005	COG0589	response to stress
BP20092_RS07010	COG0791	NLP P60 protein
BP20092_RS07010	COG3103	Sh3 type 3 domain protein
BP20092_RS07010	COG1388	LysM domain
BP20092_RS07015	COG1388	LysM domain
BP20092_RS07015	COG3942	CHAP domain
BP20092_RS07020	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
BP20092_RS07035	COG5002	protein histidine kinase activity
BP20092_RS07050	COG4716	Myosin-crossreactive antigen
BP20092_RS07065	COG0300	oxidoreductase activity
BP20092_RS07075	COG0559	Belongs to the binding-protein-dependent transport system permease family
BP20092_RS07085	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BP20092_RS07095	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
BP20092_RS07105	COG1062	S-(hydroxymethyl)glutathione dehydrogenase activity
BP20092_RS07115	COG0626	cystathionine gamma-synthase activity
BP20092_RS07120	COG0390	transport system, permease component
BP20092_RS07125	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BP20092_RS07145	COG2197	response regulator
BP20092_RS07180	COG1803	Methylglyoxal synthase
BP20092_RS07180	COG1597	lipid kinase activity
BP20092_RS07195	COG0328	RNA-DNA hybrid ribonuclease activity
BP20092_RS07220	COG0196	riboflavin kinase activity
BP20092_RS07355	COG0255	Belongs to the universal ribosomal protein uL29 family
BP20092_RS07415	COG1454	alcohol dehydrogenase
BP20092_RS07415	COG1012	belongs to the aldehyde dehydrogenase family
BP20092_RS07460	COG1739	Uncharacterized protein family UPF0029
BP20092_RS07475	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BP20092_RS07490	COG0531	amino acid
BP20092_RS07495	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BP20092_RS07535	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BP20092_RS07585	COG2252	PERMEase
BP20092_RS07595	COG0581	inorganic phosphate transmembrane transporter activity
BP20092_RS07610	COG0745	RESPONSE REGULATOR receiver
BP20092_RS07615	COG5002	protein histidine kinase activity
BP20092_RS07620	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
BP20092_RS07625	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BP20092_RS07630	COG2755	lipolytic protein G-D-S-L family
BP20092_RS07630	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BP20092_RS07635	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
BP20092_RS07640	COG3579	cysteine-type endopeptidase activity
BP20092_RS07650	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
BP20092_RS07665	COG0826	peptidase U32
BP20092_RS07685	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BP20092_RS07705	COG1704	LemA family
BP20092_RS07720	COG0039	L-malate dehydrogenase activity
BP20092_RS07745	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BP20092_RS07750	COG4770	biotin carboxylase activity
BP20092_RS07755	COG1268	BioY protein
BP20092_RS07800	COG0436	Aminotransferase
BP20092_RS07860	COG1530	ribonuclease E activity
BP20092_RS07865	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BP20092_RS07885	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BP20092_RS07955	COG0667	Aldo Keto reductase
BP20092_RS08005	COG0488	(ABC) transporter
BP20092_RS08050	COG1837	Belongs to the UPF0109 family
BP20092_RS08065	COG0742	ribosomal rna small subunit methyltransferase
BP20092_RS08070	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BP20092_RS08155	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine