locus-tag	class	description
ESN35_RS00020	COG1523	belongs to the glycosyl hydrolase 13 family
ESN35_RS00025	COG3833	ABC-type maltose transport systems, permease component
ESN35_RS00030	COG1175	transmembrane transport
ESN35_RS00050	COG1609	Transcriptional regulator
ESN35_RS00055	COG0406	alpha-ribazole phosphatase activity
ESN35_RS00070	COG4989	oxidoreductase activity
ESN35_RS00120	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
ESN35_RS00130	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
ESN35_RS00140	COG0395	ABC-type sugar transport system, permease component
ESN35_RS00165	COG0288	reversible hydration of carbon dioxide
ESN35_RS00175	COG0450	alkyl hydroperoxide reductase
ESN35_RS00180	COG1253	flavin adenine dinucleotide binding
ESN35_RS00185	COG0783	Belongs to the Dps family
ESN35_RS00205	COG0208	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ESN35_RS00210	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
ESN35_RS00230	COG0269	3-dehydro-L-gulonate-6-phosphate decarboxylase activity
ESN35_RS00235	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ESN35_RS00250	COG1609	Transcriptional regulator
ESN35_RS00255	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
ESN35_RS00265	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ESN35_RS00270	COG0187	DNA topoisomerase II activity
ESN35_RS00285	COG0592	DNA-directed DNA polymerase activity
ESN35_RS00320	COG1847	R3H domain protein
ESN35_RS00330	COG1192	Involved in chromosome partitioning
ESN35_RS00340	COG0492	ferredoxin-NADP+ reductase activity
ESN35_RS00370	COG0617	tRNA 3'-terminal CCA addition
ESN35_RS00415	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
ESN35_RS00420	COG1472	Belongs to the glycosyl hydrolase 3 family
ESN35_RS00440	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
ESN35_RS00455	COG3842	ATPase activity
ESN35_RS00470	COG1609	Transcriptional regulator
ESN35_RS00480	COG1175	transmembrane transport
ESN35_RS00490	COG2723	6-phospho-beta-galactosidase activity
ESN35_RS00495	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ESN35_RS00505	COG0474	ATPase, P-type transporting, HAD superfamily, subfamily IC
ESN35_RS00520	COG0025	NhaP-type Na H and K H
ESN35_RS00525	COG0590	tRNA wobble adenosine to inosine editing
ESN35_RS00525	COG0037	tRNA processing
ESN35_RS00545	COG1175	transmembrane transport
ESN35_RS00560	COG0366	Alpha amylase catalytic
ESN35_RS00565	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
ESN35_RS00575	COG0180	Tryptophanyl-tRNA synthetase
ESN35_RS00620	COG0058	SHG alpha-glucan phosphorylase activity
ESN35_RS00660	COG3764	Sortase (surface protein transpeptidase)
ESN35_RS00670	COG0515	serine threonine protein kinase
ESN35_RS00675	COG0768	penicillin binding
ESN35_RS00690	COG0842	Transport permease protein
ESN35_RS00690	COG1131	(ABC) transporter
ESN35_RS00690	COG1716	ATPase activity
ESN35_RS00715	COG1970	mechanosensitive ion channel activity
ESN35_RS00720	COG3760	aminoacyl-tRNA metabolism involved in translational fidelity
ESN35_RS00725	COG2226	methyltransferase
ESN35_RS00730	COG0697	spore germination
ESN35_RS00740	COG3328	transposase activity
ESN35_RS00750	COG3655	Transcriptional regulator
ESN35_RS00765	COG1476	TRANSCRIPTIONal
ESN35_RS00790	COG0343	queuine tRNA-ribosyltransferase activity
ESN35_RS00795	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
ESN35_RS00870	COG0477	Major facilitator Superfamily
ESN35_RS00880	COG1373	ATPase (AAA superfamily
ESN35_RS00895	COG0730	response to heat
ESN35_RS00900	COG1609	Transcriptional regulator
ESN35_RS00915	COG1113	amino acid transport
ESN35_RS00920	COG1175	transmembrane transport
ESN35_RS00925	COG0395	ABC-type sugar transport system, permease component
ESN35_RS00960	COG0577	efflux transmembrane transporter activity
ESN35_RS00960	COG1136	(ABC) transporter
ESN35_RS00970	COG1113	amino acid transport
ESN35_RS00975	COG1846	Transcriptional regulator
ESN35_RS00985	COG3470	protein probably involved in high-affinity Fe2 transport
ESN35_RS01055	COG1609	Transcriptional regulator
ESN35_RS01070	COG0395	ABC-type sugar transport system, permease component
ESN35_RS01100	COG1028	Short-chain dehydrogenase reductase Sdr
ESN35_RS01105	COG1075	acetyltransferases and hydrolases with the alpha beta hydrolase fold
ESN35_RS01125	COG1215	transferase activity, transferring glycosyl groups
ESN35_RS01130	COG1309	transcriptional regulator
ESN35_RS01150	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
ESN35_RS01160	COG0305	Participates in initiation and elongation during chromosome replication
ESN35_RS01165	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
ESN35_RS01190	COG0584	glycerophosphoryl diester phosphodiesterase
ESN35_RS01200	COG1484	DNA-dependent DNA replication
ESN35_RS01210	COG1653	transport
ESN35_RS01220	COG0395	ABC-type sugar transport system, permease component
ESN35_RS01235	COG3507	Belongs to the glycosyl hydrolase 43 family
ESN35_RS01280	COG0167	dihydroorotate dehydrogenase activity
ESN35_RS01285	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
ESN35_RS01295	COG1309	transcriptional regulator
ESN35_RS01315	COG1840	ABC-type Fe3 transport system, periplasmic component
ESN35_RS01350	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
ESN35_RS01355	COG1518	maintenance of DNA repeat elements
ESN35_RS01385	COG2826	transposase and inactivated derivatives, IS30 family
ESN35_RS01425	COG1088	dTDP-glucose 4,6-dehydratase activity
ESN35_RS01440	COG0463	Glycosyl transferase, family 2
ESN35_RS01465	COG1442	glycosyl transferase family 8
ESN35_RS01465	COG1216	Glycosyl transferase, family 2
ESN35_RS01470	COG1216	Glycosyl transferase, family 2
ESN35_RS01470	COG1442	glycosyl transferase family 8
ESN35_RS01475	COG1368	sulfuric ester hydrolase activity
ESN35_RS01540	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ESN35_RS01570	COG0325	Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis
ESN35_RS01575	COG0179	Fumarylacetoacetate (FAA) hydrolase
ESN35_RS01585	COG1322	Protein conserved in bacteria
ESN35_RS01605	COG1131	(ABC) transporter
ESN35_RS01655	COG0287	Prephenate dehydrogenase
ESN35_RS01655	COG1605	Chorismate mutase
ESN35_RS01665	COG0747	negative chemotaxis
ESN35_RS01675	COG0745	RESPONSE REGULATOR receiver
ESN35_RS01685	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
ESN35_RS01710	COG0356	it plays a direct role in the translocation of protons across the membrane
ESN35_RS01745	COG0355	proton-transporting ATP synthase activity, rotational mechanism
ESN35_RS01755	COG0545	Peptidyl-prolyl cis-trans isomerase
ESN35_RS01785	COG0251	oxidation-reduction process
ESN35_RS01800	COG0460	homoserine dehydrogenase
ESN35_RS01805	COG0083	homoserine kinase activity
ESN35_RS01815	COG1609	Transcriptional regulator
ESN35_RS01845	COG1022	Amp-dependent synthetase and ligase
ESN35_RS01850	COG1132	(ABC) transporter
ESN35_RS01855	COG0656	L-ascorbic acid biosynthetic process
ESN35_RS01870	COG1175	transmembrane transport
ESN35_RS01875	COG0395	ABC-type sugar transport system, permease component
ESN35_RS01890	COG1316	TRANSCRIPTIONal
ESN35_RS01895	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
ESN35_RS01925	COG3328	transposase activity
ESN35_RS01940	COG1484	DNA-dependent DNA replication
ESN35_RS01970	COG1442	glycosyl transferase family 8
ESN35_RS01970	COG1216	Glycosyl transferase, family 2
ESN35_RS01985	COG0438	transferase activity, transferring glycosyl groups
ESN35_RS01990	COG0438	transferase activity, transferring glycosyl groups
ESN35_RS02005	COG1216	Glycosyl transferase, family 2
ESN35_RS02030	COG2801	Transposase and inactivated derivatives
ESN35_RS02110	COG0489	protein tyrosine kinase activity
ESN35_RS02135	COG2814	Major facilitator Superfamily
ESN35_RS02140	COG1874	Beta-galactosidase
ESN35_RS02155	COG0395	ABC-type sugar transport system, permease component
ESN35_RS02170	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
ESN35_RS02205	COG1770	oligopeptidase
ESN35_RS02225	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ESN35_RS02230	COG1902	pentaerythritol trinitrate reductase activity
ESN35_RS02235	COG0167	dihydroorotate dehydrogenase activity
ESN35_RS02240	COG1349	DNA-binding transcription factor activity
ESN35_RS02250	COG0153	Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P)
ESN35_RS02285	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
ESN35_RS02290	COG1194	a g-specific adenine glycosylase
ESN35_RS02340	COG0210	DNA helicase
ESN35_RS02355	COG0595	An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and or decay
ESN35_RS02390	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
ESN35_RS02400	COG1653	transport
ESN35_RS02405	COG4209	transmembrane transport
ESN35_RS02410	COG0395	ABC-type sugar transport system, permease component
ESN35_RS02430	COG1621	beta-fructofuranosidase activity
ESN35_RS02450	COG0248	Ppx GppA phosphatase
ESN35_RS02460	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
ESN35_RS02480	COG1722	exodeoxyribonuclease VII activity
ESN35_RS02485	COG1570	exodeoxyribonuclease VII activity
ESN35_RS02490	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
ESN35_RS02490	COG1328	CTP reductase activity
ESN35_RS02495	COG0602	queuosine metabolic process
ESN35_RS02500	COG1940	carbohydrate kinase activity
ESN35_RS02505	COG0395	ABC-type sugar transport system, permease component
ESN35_RS02510	COG1175	transmembrane transport
ESN35_RS02515	COG2182	Extracellular solute-binding protein
ESN35_RS02520	COG1455	protein-N(PI)-phosphohistidine-lactose phosphotransferase system transporter activity
ESN35_RS02540	COG2211	Major facilitator Superfamily
ESN35_RS02570	COG1609	Transcriptional regulator
ESN35_RS02575	COG2801	Transposase and inactivated derivatives
ESN35_RS02590	COG3069	C4-dicarboxylate transmembrane transporter activity
ESN35_RS02595	COG3069	C4-dicarboxylate transmembrane transporter activity
ESN35_RS02620	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
ESN35_RS02645	COG3250	beta-galactosidase activity
ESN35_RS02650	COG1609	Transcriptional regulator
ESN35_RS02710	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
ESN35_RS02745	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
ESN35_RS02830	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
ESN35_RS02875	COG0587	DNA-directed DNA polymerase activity
ESN35_RS02885	COG0110	maltose O-acetyltransferase activity
ESN35_RS02930	COG0174	glutamine synthetase
ESN35_RS02950	COG1643	Atp-dependent helicase
ESN35_RS02960	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
ESN35_RS02990	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
ESN35_RS03015	COG0768	penicillin binding
ESN35_RS03070	COG0758	DNA mediated transformation
ESN35_RS03400	COG1940	carbohydrate kinase activity
ESN35_RS03430	COG0601	transmembrane transport
ESN35_RS03470	COG0395	ABC-type sugar transport system, permease component
ESN35_RS03480	COG1472	Belongs to the glycosyl hydrolase 3 family
ESN35_RS03495	COG0006	proline dipeptidase activity
ESN35_RS03525	COG0285	dihydrofolate synthase activity
ESN35_RS03530	COG1196	nuclear chromosome segregation
ESN35_RS03535	COG1794	racemase activity, acting on amino acids and derivatives
ESN35_RS03570	COG2017	converts alpha-aldose to the beta-anomer
ESN35_RS03580	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
ESN35_RS03595	COG0367	asparagine synthase
ESN35_RS03600	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
ESN35_RS03625	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
ESN35_RS03630	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
ESN35_RS03640	COG0477	Major facilitator Superfamily
ESN35_RS03645	COG0577	efflux transmembrane transporter activity
ESN35_RS03645	COG1136	(ABC) transporter
ESN35_RS03650	COG1217	gtp-binding protein TYPA
ESN35_RS03665	COG0287	Prephenate dehydrogenase
ESN35_RS03675	COG4166	transmembrane transport
ESN35_RS03690	COG4166	transmembrane transport
ESN35_RS03695	COG0601	transmembrane transport
ESN35_RS03700	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ESN35_RS03710	COG0708	Exodeoxyribonuclease III
ESN35_RS03740	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
ESN35_RS03775	COG2814	Major facilitator Superfamily
ESN35_RS03780	COG0670	Belongs to the BI1 family
ESN35_RS03785	COG2357	RelA SpoT domain protein
ESN35_RS03810	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ESN35_RS03820	COG1396	sequence-specific DNA binding
ESN35_RS03845	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
ESN35_RS03855	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ESN35_RS03875	COG0142	geranyltranstransferase activity
ESN35_RS03885	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
ESN35_RS03890	COG0187	DNA topoisomerase II activity
ESN35_RS03900	COG1397	ADP-ribosylglycohydrolase
ESN35_RS03905	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
ESN35_RS03905	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
ESN35_RS03925	COG1201	RNA secondary structure unwinding
ESN35_RS03930	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
ESN35_RS03955	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
ESN35_RS03975	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ESN35_RS03980	COG1055	Involved in arsenical resistance. Thought to form the channel of an arsenite pump
ESN35_RS03995	COG1882	Formate acetyltransferase
ESN35_RS04000	COG1180	Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S- adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine
ESN35_RS04050	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ESN35_RS04060	COG1611	Belongs to the LOG family
ESN35_RS04070	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
ESN35_RS04075	COG1053	succinate dehydrogenase
ESN35_RS04105	COG2873	o-acetylhomoserine
ESN35_RS04110	COG1136	(ABC) transporter
ESN35_RS04120	COG2197	response regulator
ESN35_RS04135	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
ESN35_RS04140	COG0012	GTP binding
ESN35_RS04175	COG0583	DNA-binding transcription factor activity
ESN35_RS04205	COG2233	PERMEase
ESN35_RS04210	COG0390	transport system, permease component
ESN35_RS04215	COG1136	(ABC) transporter
ESN35_RS04220	COG4221	oxidoreductase activity
ESN35_RS04230	COG1284	Uncharacterised 5xTM membrane BCR, YitT family COG1284
ESN35_RS04235	COG1114	Component of the transport system for branched-chain amino acids
ESN35_RS04240	COG1168	Bifunctional PLP-dependent enzyme with beta-cystaTHIonase and maltose regulon repressor activities
ESN35_RS04255	COG1472	Belongs to the glycosyl hydrolase 3 family
ESN35_RS04280	COG2116	formate transmembrane transporter activity
ESN35_RS04290	COG1116	anion transmembrane transporter activity
ESN35_RS04300	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ESN35_RS04330	COG1760	l-serine dehydratase
ESN35_RS04340	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
ESN35_RS04365	COG1316	TRANSCRIPTIONal
ESN35_RS04370	COG1316	TRANSCRIPTIONal
ESN35_RS04400	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
ESN35_RS04405	COG2205	protein histidine kinase activity
ESN35_RS04410	COG0745	RESPONSE REGULATOR receiver
ESN35_RS04420	COG1329	Transcriptional regulator
ESN35_RS04435	COG1121	(ABC) transporter
ESN35_RS04450	COG0539	negative regulation of cytoplasmic translation
ESN35_RS04465	COG0469	pyruvate kinase activity
ESN35_RS04485	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
ESN35_RS04520	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
ESN35_RS04525	COG0280	phosphate acetyltransferase
ESN35_RS04525	COG0857	belongs to the CobB CobQ family
ESN35_RS04545	COG0306	phosphate transporter
ESN35_RS04555	COG2197	response regulator
ESN35_RS04560	COG4585	Histidine kinase
ESN35_RS04565	COG1131	(ABC) transporter
ESN35_RS04610	COG0588	phosphoglycerate mutase activity
ESN35_RS04655	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
ESN35_RS04660	COG2153	protein acetylation
ESN35_RS04675	COG0719	Fe-S assembly protein
ESN35_RS04680	COG0396	ATPase activity
ESN35_RS04685	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
ESN35_RS04695	COG2151	metal-sulfur cluster biosynthetic enzyme
ESN35_RS04780	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
ESN35_RS04990	COG1388	LysM domain
ESN35_RS04990	COG3942	CHAP domain
ESN35_RS05005	COG1385	rRNA (uridine-N3-)-methyltransferase activity
ESN35_RS05010	COG0537	adenosine 5'-monophosphoramidase activity
ESN35_RS05015	COG1702	phosphate starvation-inducible protein PhoH
ESN35_RS05035	COG1022	Amp-dependent synthetase and ligase
ESN35_RS05040	COG3288	NAD(P)+ transhydrogenase (AB-specific) activity
ESN35_RS05065	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
ESN35_RS05070	COG2860	membrane
ESN35_RS05085	COG0635	Involved in the biosynthesis of porphyrin-containing compound
ESN35_RS05090	COG0067	glutamate synthase
ESN35_RS05090	COG0069	glutamate synthase activity
ESN35_RS05090	COG0070	glutamate synthase
ESN35_RS05105	COG0297	glycogen (starch) synthase activity
ESN35_RS05110	COG1119	ATPase activity
ESN35_RS05140	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
ESN35_RS05160	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
ESN35_RS05165	COG0284	orotidine-5'-phosphate decarboxylase activity
ESN35_RS05170	COG0543	2 iron, 2 sulfur cluster binding
ESN35_RS05175	COG0167	dihydroorotate dehydrogenase activity
ESN35_RS05210	COG1686	Belongs to the peptidase S11 family
ESN35_RS05225	COG0583	DNA-binding transcription factor activity
ESN35_RS05230	COG1011	Hydrolase
ESN35_RS05240	COG1063	alcohol dehydrogenase
ESN35_RS05285	COG0488	(ABC) transporter
ESN35_RS05305	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
ESN35_RS05330	COG1314	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
ESN35_RS05345	COG0436	Aminotransferase
ESN35_RS05350	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
ESN35_RS05370	COG3001	Fructosamine kinase
ESN35_RS05460	COG0045	succinate-CoA ligase (ADP-forming) activity
ESN35_RS05485	COG0580	Belongs to the MIP aquaporin (TC 1.A.8) family
ESN35_RS05530	COG0546	phosphoglycolate phosphatase activity
ESN35_RS05575	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
ESN35_RS05580	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
ESN35_RS05585	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
ESN35_RS05685	COG1716	ATPase activity
ESN35_RS05705	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
ESN35_RS05720	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
ESN35_RS05735	COG0133	tryptophan synthase activity
ESN35_RS05755	COG0575	Belongs to the CDS family
ESN35_RS05790	COG1022	Amp-dependent synthetase and ligase
ESN35_RS05800	COG0516	GMP reductase activity
ESN35_RS05815	COG1022	Amp-dependent synthetase and ligase
ESN35_RS05890	COG1192	Involved in chromosome partitioning
ESN35_RS06120	COG0551	DNA topoisomerase type I activity
ESN35_RS06120	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ESN35_RS06200	COG3550	peptidyl-serine autophosphorylation
ESN35_RS06205	COG4974	Belongs to the 'phage' integrase family
ESN35_RS06235	COG0802	atpase or kinase
ESN35_RS06250	COG1596	polysaccharide export
ESN35_RS06250	COG1555	photosystem II stabilization
ESN35_RS06260	COG0598	Magnesium transport protein CorA
ESN35_RS06275	COG1131	(ABC) transporter
ESN35_RS06280	COG1725	Transcriptional regulator
ESN35_RS06330	COG3657	addiction module killer protein
ESN35_RS06370	COG0406	alpha-ribazole phosphatase activity
ESN35_RS06375	COG0799	negative regulation of ribosome biogenesis
ESN35_RS06395	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
ESN35_RS06470	COG0582	viral genome integration into host DNA
ESN35_RS06885	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ESN35_RS06900	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
ESN35_RS06905	COG0569	domain protein
ESN35_RS06950	COG0512	Glutamine amidotransferase of anthranilate synthase
ESN35_RS06950	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
ESN35_RS07030	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
ESN35_RS07050	COG1122	ATPase activity
ESN35_RS07055	COG4721	ABC-type cobalt transport system, permease component
ESN35_RS07090	COG0488	(ABC) transporter
ESN35_RS07100	COG0446	pyridine nucleotide-disulphide oxidoreductase
ESN35_RS07125	COG1122	ATPase activity
ESN35_RS07170	COG0819	Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway
ESN35_RS07175	COG1534	Rna-binding protein
ESN35_RS07185	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
ESN35_RS07200	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
ESN35_RS07220	COG3549	Plasmid maintenance system killer
ESN35_RS07235	COG1929	Belongs to the glycerate kinase type-1 family
ESN35_RS07240	COG0456	acetyltransferase
ESN35_RS07250	COG2361	Protein of unknown function DUF86
ESN35_RS07275	COG0494	nUDIX hydrolase
ESN35_RS07300	COG2801	Transposase and inactivated derivatives
ESN35_RS07360	COG1484	DNA-dependent DNA replication
ESN35_RS07410	COG0477	Major facilitator Superfamily
ESN35_RS07420	COG2071	gamma-glutamyl-gamma-aminobutyrate hydrolase activity
ESN35_RS07435	COG2326	polyphosphate kinase activity
ESN35_RS07440	COG0765	amino acid transport
ESN35_RS07445	COG0765	amino acid transport
ESN35_RS07450	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ESN35_RS07455	COG1126	abc transporter atp-binding protein
ESN35_RS07470	COG1196	nuclear chromosome segregation
ESN35_RS07485	COG1278	Cold shock
ESN35_RS07490	COG2205	protein histidine kinase activity
ESN35_RS07495	COG0745	RESPONSE REGULATOR receiver
ESN35_RS07525	COG0714	Associated with various cellular activities
ESN35_RS07580	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
ESN35_RS07610	COG4122	O-methyltransferase activity
ESN35_RS07615	COG1222	aaa ATPase
ESN35_RS07620	COG0586	Pfam SNARE associated Golgi protein
ESN35_RS07625	COG0560	Phosphoserine phosphatase
ESN35_RS07640	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
ESN35_RS07670	COG0463	Glycosyl transferase, family 2
ESN35_RS07680	COG0284	orotidine-5'-phosphate decarboxylase activity
ESN35_RS07750	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
ESN35_RS07775	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ESN35_RS07795	COG1012	belongs to the aldehyde dehydrogenase family
ESN35_RS07800	COG1028	Short-chain dehydrogenase reductase Sdr
ESN35_RS07820	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
ESN35_RS07825	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
ESN35_RS07835	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
ESN35_RS07885	COG0789	Transcriptional regulator
ESN35_RS07890	COG3655	Transcriptional regulator
ESN35_RS07910	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
ESN35_RS07925	COG0514	ATP-dependent DNA helicase (RecQ)
ESN35_RS07980	COG1129	ABC transporter
ESN35_RS07995	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
ESN35_RS08000	COG0601	transmembrane transport
ESN35_RS08005	COG4166	transmembrane transport
ESN35_RS08020	COG1653	transport
ESN35_RS08025	COG3534	alpha-L-arabinofuranosidase
ESN35_RS08035	COG0395	ABC-type sugar transport system, permease component
ESN35_RS08040	COG1175	transmembrane transport
ESN35_RS08045	COG1609	Transcriptional regulator
ESN35_RS08050	COG0564	pseudouridine synthase activity
ESN35_RS08055	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
ESN35_RS08065	COG1705	Flagellar rod assembly protein muramidase FlgJ
ESN35_RS08065	COG3942	CHAP domain
ESN35_RS08070	COG2177	Part of the ABC transporter FtsEX involved in
ESN35_RS08075	COG2884	Cell division ATP-binding protein ftsE
ESN35_RS08080	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
ESN35_RS08120	COG0024	Methionine aminopeptidase
ESN35_RS08130	COG3590	peptidase
ESN35_RS08155	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
ESN35_RS08170	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
ESN35_RS08215	COG1070	Carbohydrate kinase
ESN35_RS08225	COG1979	alcohol dehydrogenase
ESN35_RS08240	COG2272	Belongs to the type-B carboxylesterase lipase family
ESN35_RS08250	COG3507	Belongs to the glycosyl hydrolase 43 family
ESN35_RS08255	COG0395	ABC-type sugar transport system, permease component
ESN35_RS08260	COG1175	transmembrane transport
ESN35_RS08270	COG1609	Transcriptional regulator
ESN35_RS08280	COG3507	Belongs to the glycosyl hydrolase 43 family
ESN35_RS08295	COG1373	ATPase (AAA superfamily
ESN35_RS08305	COG2873	o-acetylhomoserine
ESN35_RS08315	COG3328	transposase activity
ESN35_RS08340	COG0242	peptide deformylase activity
ESN35_RS08395	COG1946	Acyl-CoA thioesterase
ESN35_RS08410	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
ESN35_RS08415	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
ESN35_RS08450	COG1454	alcohol dehydrogenase
ESN35_RS08465	COG0583	DNA-binding transcription factor activity
ESN35_RS08470	COG2249	NAD(P)H dehydrogenase (quinone) activity
ESN35_RS08510	COG3177	Filamentation induced by cAMP protein fic
ESN35_RS08540	COG4721	ABC-type cobalt transport system, permease component
ESN35_RS08545	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
ESN35_RS08600	COG0589	response to stress
ESN35_RS08605	COG1388	LysM domain
ESN35_RS08605	COG0791	NLP P60 protein
ESN35_RS08605	COG3103	Sh3 type 3 domain protein
ESN35_RS08610	COG3942	CHAP domain
ESN35_RS08610	COG1388	LysM domain
ESN35_RS08615	COG1388	LysM domain
ESN35_RS08615	COG3942	CHAP domain
ESN35_RS08620	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
ESN35_RS08630	COG5002	protein histidine kinase activity
ESN35_RS08635	COG0704	Plays a role in the regulation of phosphate uptake
ESN35_RS08640	COG4716	Myosin-crossreactive antigen
ESN35_RS08660	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
ESN35_RS08670	COG2814	Major facilitator Superfamily
ESN35_RS08700	COG2197	response regulator
ESN35_RS08725	COG0395	ABC-type sugar transport system, permease component
ESN35_RS08730	COG1175	transmembrane transport
ESN35_RS08760	COG1597	lipid kinase activity
ESN35_RS08760	COG1803	Methylglyoxal synthase
ESN35_RS08770	COG0366	Alpha amylase catalytic
ESN35_RS08775	COG0328	RNA-DNA hybrid ribonuclease activity
ESN35_RS08800	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
ESN35_RS08805	COG0402	S-adenosylhomocysteine deaminase activity
ESN35_RS08815	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
ESN35_RS08820	COG0765	amino acid transport
ESN35_RS08825	COG1126	abc transporter atp-binding protein
ESN35_RS08830	COG0196	riboflavin kinase activity
ESN35_RS08965	COG0255	Belongs to the universal ribosomal protein uL29 family
ESN35_RS09020	COG1012	belongs to the aldehyde dehydrogenase family
ESN35_RS09020	COG1454	alcohol dehydrogenase
ESN35_RS09025	COG1523	belongs to the glycosyl hydrolase 13 family
ESN35_RS09050	COG1739	Uncharacterized protein family UPF0029
ESN35_RS09060	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
ESN35_RS09095	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
ESN35_RS09110	COG0531	amino acid
ESN35_RS09115	COG0812	UDP-N-acetylmuramate dehydrogenase activity
ESN35_RS09140	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
ESN35_RS09150	COG0714	Associated with various cellular activities
ESN35_RS09210	COG2252	PERMEase
ESN35_RS09235	COG0745	RESPONSE REGULATOR receiver
ESN35_RS09240	COG5002	protein histidine kinase activity
ESN35_RS09245	COG0775	Catalyzes the irreversible cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH AdoHcy) to adenine and the corresponding thioribose, 5'-methylthioribose and S-ribosylhomocysteine, respectively
ESN35_RS09250	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ESN35_RS09255	COG0722	Stereospecific condensation of phosphoenolpyruvate (PEP) and D-erythrose-4-phosphate (E4P) giving rise to 3-deoxy-D- arabino-heptulosonate-7-phosphate (DAHP)
ESN35_RS09260	COG3579	cysteine-type endopeptidase activity
ESN35_RS09270	COG2039	Removes 5-oxoproline from various penultimate amino acid residues except L-proline
ESN35_RS09280	COG1496	oxidoreductase activity
ESN35_RS09285	COG0826	peptidase U32
ESN35_RS09300	COG1704	LemA family
ESN35_RS09345	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
ESN35_RS09350	COG4770	biotin carboxylase activity
ESN35_RS09355	COG1268	BioY protein
ESN35_RS09360	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
ESN35_RS09360	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
ESN35_RS09390	COG0250	Participates in transcription elongation, termination and antitermination
ESN35_RS09405	COG0436	Aminotransferase
ESN35_RS09430	COG1530	ribonuclease E activity
ESN35_RS09435	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
ESN35_RS09455	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
ESN35_RS09525	COG0667	Aldo Keto reductase
ESN35_RS09575	COG1487	ribonuclease activity
ESN35_RS09580	COG0488	(ABC) transporter
ESN35_RS09585	COG0505	Belongs to the CarA family
ESN35_RS09615	COG1837	Belongs to the UPF0109 family
ESN35_RS09665	COG2270	Major facilitator Superfamily
ESN35_RS09680	COG0110	maltose O-acetyltransferase activity
ESN35_RS09700	COG1414	Transcriptional regulator
ESN35_RS09735	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
ESN35_RS09745	COG0395	ABC-type sugar transport system, permease component
ESN35_RS09750	COG1175	transmembrane transport
ESN35_RS09755	COG1653	transport
ESN35_RS09760	COG1609	Transcriptional regulator
ESN35_RS09765	COG3152	Membrane
ESN35_RS09815	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
ESN35_RS09825	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
ESN35_RS09825	COG1754	DNA topoisomerase type I activity
ESN35_RS09850	COG1260	myo-inositol-1-phosphate synthase
ESN35_RS09855	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
ESN35_RS09865	COG1609	Transcriptional regulator
ESN35_RS09870	COG0395	ABC-type sugar transport system, permease component
ESN35_RS09875	COG1175	transmembrane transport
ESN35_RS09880	COG1653	transport
ESN35_RS09885	COG3940	Belongs to the glycosyl hydrolase 43 family
ESN35_RS09890	COG1609	Transcriptional regulator
ESN35_RS09900	COG3507	Belongs to the glycosyl hydrolase 43 family
ESN35_RS09905	COG3507	Belongs to the glycosyl hydrolase 43 family
ESN35_RS09970	COG1597	lipid kinase activity
ESN35_RS10010	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
ESN35_RS10015	COG0406	alpha-ribazole phosphatase activity
ESN35_RS10015	COG0494	nUDIX hydrolase
ESN35_RS10025	COG1609	Transcriptional regulator
ESN35_RS10045	COG1501	Belongs to the glycosyl hydrolase 31 family
ESN35_RS10055	COG1501	Belongs to the glycosyl hydrolase 31 family
ESN35_RS10060	COG0395	ABC-type sugar transport system, permease component
ESN35_RS10065	COG1175	transmembrane transport
ESN35_RS10080	COG3534	alpha-L-arabinofuranosidase
ESN35_RS10095	COG0084	hydrolase, TatD family'
ESN35_RS10155	COG1132	(ABC) transporter
ESN35_RS10160	COG1132	(ABC) transporter
ESN35_RS10165	COG0667	Aldo Keto reductase
ESN35_RS10175	COG2211	Major facilitator Superfamily
ESN35_RS10180	COG2211	Major facilitator Superfamily
ESN35_RS10220	COG1959	2 iron, 2 sulfur cluster binding
ESN35_RS10225	COG2910	NAD(P)H-binding
ESN35_RS10230	COG3459	Glycosyltransferase 36 associated
ESN35_RS10245	COG1940	carbohydrate kinase activity
ESN35_RS10255	COG3507	Belongs to the glycosyl hydrolase 43 family
ESN35_RS10260	COG2730	Belongs to the glycosyl hydrolase 5 (cellulase A) family
ESN35_RS10265	COG1501	Belongs to the glycosyl hydrolase 31 family
ESN35_RS10280	COG1472	Belongs to the glycosyl hydrolase 3 family
ESN35_RS10300	COG0395	ABC-type sugar transport system, permease component
ESN35_RS10305	COG4209	transmembrane transport
ESN35_RS10330	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
ESN35_RS10335	COG0789	Transcriptional regulator
ESN35_RS10340	COG0484	heat shock protein binding
ESN35_RS10370	COG0395	ABC-type sugar transport system, permease component
ESN35_RS10375	COG1175	transmembrane transport
ESN35_RS10385	COG1609	Transcriptional regulator
ESN35_RS10390	COG0366	Alpha amylase catalytic
ESN35_RS10415	COG1192	Involved in chromosome partitioning
ESN35_RS10435	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis