locus-tag	class	description
GMA17_RS00020	COG1087	Belongs to the NAD(P)-dependent epimerase dehydratase family
GMA17_RS00030	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GMA17_RS00035	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
GMA17_RS00040	COG2509	5-formyltetrahydrofolate cyclo-ligase activity
GMA17_RS00045	COG0038	chloride channel
GMA17_RS00050	COG0262	Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis
GMA17_RS00060	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
GMA17_RS00065	COG1972	Belongs to the concentrative nucleoside transporter (CNT) (TC 2.A.41) family
GMA17_RS00075	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
GMA17_RS00080	COG2086	electron transfer activity
GMA17_RS00085	COG0022	dehydrogenase e1 component
GMA17_RS00085	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMA17_RS00095	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
GMA17_RS00100	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
GMA17_RS00110	COG1428	Deoxynucleoside kinase
GMA17_RS00150	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
GMA17_RS00185	COG1131	(ABC) transporter
GMA17_RS00190	COG0077	Prephenate dehydratase
GMA17_RS00190	COG1605	Chorismate mutase
GMA17_RS00195	COG0436	Aminotransferase
GMA17_RS00200	COG0287	Prephenate dehydrogenase
GMA17_RS00205	COG2876	3-deoxy-7-phosphoheptulonate synthase activity
GMA17_RS00210	COG1162	GTPase activity
GMA17_RS00215	COG1490	D-aminoacyl-tRNA deacylase activity
GMA17_RS00230	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
GMA17_RS00235	COG0820	rRNA (adenine-C2-)-methyltransferase activity
GMA17_RS00240	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
GMA17_RS00270	COG2936	dipeptidyl-peptidase activity
GMA17_RS00280	COG0358	DNA primase activity
GMA17_RS00290	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
GMA17_RS00310	COG0772	Belongs to the SEDS family
GMA17_RS00315	COG0768	penicillin binding
GMA17_RS00330	COG1077	Cell shape determining protein MreB Mrl
GMA17_RS00335	COG0138	bifunctional purine biosynthesis protein purh
GMA17_RS00380	COG0459	protein refolding
GMA17_RS00385	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
GMA17_RS00410	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GMA17_RS00420	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
GMA17_RS00420	COG1754	DNA topoisomerase type I activity
GMA17_RS00430	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMA17_RS00460	COG0488	(ABC) transporter
GMA17_RS00520	COG0668	transmembrane transport
GMA17_RS00525	COG0589	response to stress
GMA17_RS00545	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
GMA17_RS00555	COG0671	phosphoesterase, PA-phosphatase related
GMA17_RS00585	COG0587	DNA-directed DNA polymerase activity
GMA17_RS00590	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GMA17_RS00610	COG1132	(ABC) transporter
GMA17_RS00630	COG2003	Belongs to the UPF0758 family
GMA17_RS00645	COG1011	Hydrolase
GMA17_RS00655	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
GMA17_RS00665	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GMA17_RS00685	COG1629	transport
GMA17_RS00685	COG4206	TonB-dependent receptor
GMA17_RS00695	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
GMA17_RS00700	COG0049	tRNA binding
GMA17_RS00705	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
GMA17_RS00710	COG0051	transcription antitermination factor activity, RNA binding
GMA17_RS00715	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
GMA17_RS00720	COG0088	Forms part of the polypeptide exit tunnel
GMA17_RS00725	COG0089	rRNA binding
GMA17_RS00730	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
GMA17_RS00735	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
GMA17_RS00740	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
GMA17_RS00745	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
GMA17_RS00750	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
GMA17_RS00755	COG0255	Belongs to the universal ribosomal protein uL29 family
GMA17_RS00760	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
GMA17_RS00765	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
GMA17_RS00770	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
GMA17_RS00775	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
GMA17_RS00780	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
GMA17_RS00785	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
GMA17_RS00790	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
GMA17_RS00795	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
GMA17_RS00800	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
GMA17_RS00805	COG1841	ribosomal large subunit assembly
GMA17_RS00810	COG0200	Binds to the 23S rRNA
GMA17_RS00820	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
GMA17_RS00825	COG0257	Belongs to the bacterial ribosomal protein bL36 family
GMA17_RS00830	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
GMA17_RS00835	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
GMA17_RS00840	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
GMA17_RS00845	COG0202	RNA polymerase activity
GMA17_RS00850	COG0203	ribosomal protein L17
GMA17_RS00855	COG0505	Belongs to the CarA family
GMA17_RS00860	COG0148	phosphopyruvate hydratase activity
GMA17_RS00875	COG2234	aminopeptidase activity
GMA17_RS00880	COG2353	YceI-like domain
GMA17_RS00935	COG1190	Belongs to the class-II aminoacyl-tRNA synthetase family
GMA17_RS00940	COG0401	homolog of Blt101
GMA17_RS00945	COG0321	lipoyl(octanoyl) transferase activity
GMA17_RS01010	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
GMA17_RS01045	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GMA17_RS01050	COG1960	acyl-CoA dehydrogenase activity
GMA17_RS01070	COG0811	peptide transport
GMA17_RS01075	COG0848	biopolymer transport protein
GMA17_RS01085	COG0285	dihydrofolate synthase activity
GMA17_RS01100	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
GMA17_RS01120	COG0295	cytidine deaminase activity
GMA17_RS01130	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMA17_RS01140	COG4221	oxidoreductase activity
GMA17_RS01160	COG0018	arginyl-trna synthetase
GMA17_RS01195	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
GMA17_RS01205	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
GMA17_RS01220	COG1187	pseudouridine synthase activity
GMA17_RS01240	COG0433	COG0433 Predicted ATPase
GMA17_RS01245	COG0602	queuosine metabolic process
GMA17_RS01255	COG0367	asparagine synthase
GMA17_RS01270	COG0187	DNA topoisomerase II activity
GMA17_RS01285	COG0039	L-malate dehydrogenase activity
GMA17_RS01295	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
GMA17_RS01305	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GMA17_RS01310	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
GMA17_RS01315	COG0215	cysteine-tRNA ligase activity
GMA17_RS01325	COG0302	gtp cyclohydrolase
GMA17_RS01345	COG0442	prolyl-tRNA aminoacylation
GMA17_RS01355	COG0268	Binds directly to 16S ribosomal RNA
GMA17_RS01375	COG0101	tRNA pseudouridine synthase activity
GMA17_RS01380	COG1132	(ABC) transporter
GMA17_RS01395	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
GMA17_RS01415	COG0149	triose-phosphate isomerase activity
GMA17_RS01420	COG2264	protein methyltransferase activity
GMA17_RS01480	COG0610	Subunit R is required for both nuclease and ATPase activities, but not for modification
GMA17_RS01510	COG2356	endonuclease I
GMA17_RS01550	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
GMA17_RS01565	COG1121	(ABC) transporter
GMA17_RS01570	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
GMA17_RS01575	COG0284	orotidine-5'-phosphate decarboxylase activity
GMA17_RS01580	COG4607	ABC-type enterochelin transport system periplasmic component
GMA17_RS01600	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMA17_RS01600	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMA17_RS01600	COG1703	isobutyryl-CoA mutase activity
GMA17_RS01615	COG1595	DNA-templated transcription, initiation
GMA17_RS01620	COG0513	Belongs to the DEAD box helicase family
GMA17_RS01630	COG1522	sequence-specific DNA binding
GMA17_RS01655	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
GMA17_RS01680	COG0115	Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family
GMA17_RS01695	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
GMA17_RS01695	COG4121	Catalyzes the last two steps in the biosynthesis of 5- methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at the wobble position (U34) in tRNA. Catalyzes the FAD-dependent demodification of cmnm(5)s(2)U34 to nm(5)s(2)U34, followed by the transfer of a methyl group from S-adenosyl-L-methionine to nm(5)s(2)U34, to form mnm(5)s(2)U34
GMA17_RS01710	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
GMA17_RS01715	COG0484	heat shock protein binding
GMA17_RS01720	COG4152	abc transporter atp-binding protein
GMA17_RS01725	COG1668	transmembrane transport
GMA17_RS01730	COG1196	nuclear chromosome segregation
GMA17_RS01730	COG3264	Mechanosensitive ion channel
GMA17_RS01740	COG2326	polyphosphate kinase activity
GMA17_RS01805	COG3279	Response regulator of the LytR AlgR family
GMA17_RS01820	COG0045	succinate-CoA ligase (ADP-forming) activity
GMA17_RS01825	COG0175	sulfate reduction
GMA17_RS01840	COG0556	nucleotide-excision repair
GMA17_RS01890	COG1612	heme a metabolic process
GMA17_RS01900	COG0617	tRNA 3'-terminal CCA addition
GMA17_RS01905	COG0009	L-threonylcarbamoyladenylate synthase
GMA17_RS01925	COG1216	Glycosyl transferase, family 2
GMA17_RS01930	COG1216	Glycosyl transferase, family 2
GMA17_RS01950	COG0463	Glycosyl transferase, family 2
GMA17_RS01960	COG2171	N-acyltransferase activity
GMA17_RS01965	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
GMA17_RS01980	COG0242	peptide deformylase activity
GMA17_RS01990	COG3956	TIGRFAM MazG family protein
GMA17_RS02000	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
GMA17_RS02020	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
GMA17_RS02030	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
GMA17_RS02040	COG0317	In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance
GMA17_RS02050	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMA17_RS02060	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
GMA17_RS02065	COG0714	Associated with various cellular activities
GMA17_RS02070	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
GMA17_RS02075	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMA17_RS02115	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
GMA17_RS02120	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GMA17_RS02125	COG1188	Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit, (S4 paralog))
GMA17_RS02140	COG3958	Transketolase
GMA17_RS02145	COG3959	Transketolase, thiamine diphosphate binding domain
GMA17_RS02150	COG0343	queuine tRNA-ribosyltransferase activity
GMA17_RS02165	COG0825	malonyl-CoA metabolic process
GMA17_RS02170	COG0305	Participates in initiation and elongation during chromosome replication
GMA17_RS02175	COG0628	permease
GMA17_RS02190	COG3279	Response regulator of the LytR AlgR family
GMA17_RS02200	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
GMA17_RS02205	COG0291	Belongs to the bacterial ribosomal protein bL35 family
GMA17_RS02210	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
GMA17_RS02215	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
GMA17_RS02250	COG2103	Specifically catalyzes the cleavage of the D-lactyl ether substituent of MurNAc 6-phosphate, producing GlcNAc 6- phosphate and D-lactate
GMA17_RS02290	COG0335	large ribosomal subunit rRNA binding
GMA17_RS02295	COG0336	Belongs to the RNA methyltransferase TrmD family
GMA17_RS02310	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
GMA17_RS02315	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
GMA17_RS02325	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
GMA17_RS02350	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
GMA17_RS02355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
GMA17_RS02360	COG0824	Thioesterase
GMA17_RS02365	COG1739	Uncharacterized protein family UPF0029
GMA17_RS02380	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GMA17_RS02380	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
GMA17_RS02385	COG0456	acetyltransferase
GMA17_RS02390	COG2890	protein-(glutamine-N5) methyltransferase activity
GMA17_RS02395	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GMA17_RS02410	COG0737	Belongs to the 5'-nucleotidase family
GMA17_RS02415	COG4085	toxin activity
GMA17_RS02415	COG1525	nuclease
GMA17_RS02415	COG0737	Belongs to the 5'-nucleotidase family
GMA17_RS02425	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
GMA17_RS02450	COG0497	DNA recombination
GMA17_RS02455	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
GMA17_RS02470	COG0463	Glycosyl transferase, family 2
GMA17_RS02470	COG1216	Glycosyl transferase, family 2
GMA17_RS02480	COG0237	dephospho-CoA kinase activity
GMA17_RS02495	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
GMA17_RS02500	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GMA17_RS02525	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMA17_RS02530	COG0673	inositol 2-dehydrogenase activity
GMA17_RS02535	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
GMA17_RS02550	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
GMA17_RS02565	COG0813	purine-nucleoside phosphorylase activity
GMA17_RS02570	COG0274	Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy- D-ribose 5-phosphate
GMA17_RS02575	COG3047	cAMP biosynthetic process
GMA17_RS02585	COG0542	response to heat
GMA17_RS02610	COG0385	Bile acid
GMA17_RS02620	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
GMA17_RS02645	COG0300	oxidoreductase activity
GMA17_RS02650	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
GMA17_RS02660	COG0488	(ABC) transporter
GMA17_RS02670	COG1278	Cold shock
GMA17_RS02690	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
GMA17_RS02720	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
GMA17_RS02735	COG3275	phosphorelay sensor kinase activity
GMA17_RS02740	COG3279	Response regulator of the LytR AlgR family
GMA17_RS02745	COG0069	glutamate synthase activity
GMA17_RS02755	COG0210	DNA helicase
GMA17_RS02765	COG0009	L-threonylcarbamoyladenylate synthase
GMA17_RS02795	COG0693	protein deglycase activity
GMA17_RS02805	COG2259	Doxx family
GMA17_RS02810	COG0022	dehydrogenase e1 component
GMA17_RS02825	COG1611	Belongs to the LOG family
GMA17_RS02835	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GMA17_RS02865	COG0405	Gamma-glutamyltransferase
GMA17_RS02875	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GMA17_RS02895	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMA17_RS02900	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
GMA17_RS02940	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
GMA17_RS02975	COG3279	Response regulator of the LytR AlgR family
GMA17_RS02980	COG2972	Histidine kinase
GMA17_RS02995	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GMA17_RS03020	COG2217	Heavy metal translocating P-type atpase
GMA17_RS03040	COG0006	proline dipeptidase activity
GMA17_RS03065	COG1289	transmembrane transporter activity
GMA17_RS03075	COG0592	DNA-directed DNA polymerase activity
GMA17_RS03095	COG1702	phosphate starvation-inducible protein PhoH
GMA17_RS03105	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
GMA17_RS03120	COG1115	amino acid carrier protein
GMA17_RS03135	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
GMA17_RS03145	COG0019	diaminopimelate decarboxylase activity
GMA17_RS03155	COG2095	MarC family integral membrane protein
GMA17_RS03160	COG2814	Major facilitator Superfamily
GMA17_RS03165	COG3852	Histidine kinase
GMA17_RS03180	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMA17_RS03185	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GMA17_RS03195	COG3591	Belongs to the peptidase S1B family
GMA17_RS03210	COG2319	Wd-40 repeat
GMA17_RS03210	COG4249	Peptidase C14 caspase catalytic subunit p20
GMA17_RS03230	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GMA17_RS03235	COG0439	Biotin carboxylase
GMA17_RS03245	COG2339	peptidase activity
GMA17_RS03250	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GMA17_RS03270	COG1272	protein, Hemolysin III
GMA17_RS03275	COG2095	MarC family integral membrane protein
GMA17_RS03295	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMA17_RS03295	COG0116	Belongs to the methyltransferase superfamily
GMA17_RS03310	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
GMA17_RS03360	COG1104	cysteine desulfurase activity
GMA17_RS03400	COG1418	mRNA catabolic process
GMA17_RS03405	COG4974	Belongs to the 'phage' integrase family
GMA17_RS03430	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
GMA17_RS03435	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMA17_RS03455	COG2270	Major facilitator Superfamily
GMA17_RS03495	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
GMA17_RS03505	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
GMA17_RS03510	COG0539	negative regulation of cytoplasmic translation
GMA17_RS03515	COG2065	Also displays a weak uracil phosphoribosyltransferase activity which is not physiologically significant
GMA17_RS03520	COG0540	Belongs to the ATCase OTCase family
GMA17_RS03530	COG1234	tRNA 3'-trailer cleavage
GMA17_RS03540	COG0259	pyridoxamine-phosphate oxidase activity
GMA17_RS03555	COG2885	chlorophyll binding
GMA17_RS03580	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
GMA17_RS03605	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
GMA17_RS03610	COG2226	methyltransferase
GMA17_RS03655	COG3657	addiction module killer protein
GMA17_RS03660	COG3636	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GMA17_RS03750	COG0656	L-ascorbic acid biosynthetic process
GMA17_RS03760	COG0742	ribosomal rna small subunit methyltransferase
GMA17_RS03775	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
GMA17_RS03785	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
GMA17_RS03795	COG1454	alcohol dehydrogenase
GMA17_RS03820	COG0217	transcriptional regulatory protein
GMA17_RS03825	COG2154	pterin-4-alpha-carbinolamine dehydratase
GMA17_RS03835	COG2066	Belongs to the glutaminase family
GMA17_RS03840	COG0404	The glycine cleavage system catalyzes the degradation of glycine
GMA17_RS03845	COG0006	proline dipeptidase activity
GMA17_RS03855	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
GMA17_RS03860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMA17_RS03865	COG2986	histidine ammonia-lyase
GMA17_RS03875	COG0542	response to heat
GMA17_RS03880	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
GMA17_RS03890	COG0791	NLP P60 protein
GMA17_RS03895	COG0183	Belongs to the thiolase family
GMA17_RS03905	COG1505	serine-type exopeptidase activity
GMA17_RS03925	COG0300	oxidoreductase activity
GMA17_RS03950	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
GMA17_RS03960	COG0628	permease
GMA17_RS03985	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
GMA17_RS03995	COG0205	6-phosphofructokinase activity
GMA17_RS04030	COG0251	oxidation-reduction process
GMA17_RS04040	COG0860	N-Acetylmuramoyl-L-alanine amidase
GMA17_RS04050	COG2181	nitrate reductase activity
GMA17_RS04050	COG0247	lactate metabolic process
GMA17_RS04065	COG2181	nitrate reductase activity
GMA17_RS04065	COG0247	lactate metabolic process
GMA17_RS04095	COG1472	Belongs to the glycosyl hydrolase 3 family
GMA17_RS04100	COG0438	transferase activity, transferring glycosyl groups
GMA17_RS04125	COG0277	FAD linked oxidase domain protein
GMA17_RS04125	COG0247	lactate metabolic process
GMA17_RS04130	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
GMA17_RS04135	COG1301	dicarboxylic acid transport
GMA17_RS04140	COG0189	ligase activity
GMA17_RS04185	COG4771	TonB-dependent receptor
GMA17_RS04205	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
GMA17_RS04210	COG1932	Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine
GMA17_RS04220	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
GMA17_RS04225	COG0012	GTP binding
GMA17_RS04255	COG0861	Integral membrane protein TerC family
GMA17_RS04275	COG1522	sequence-specific DNA binding
GMA17_RS04285	COG0337	Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ)
GMA17_RS04310	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GMA17_RS04330	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GMA17_RS04335	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GMA17_RS04345	COG0367	asparagine synthase
GMA17_RS04350	COG0297	glycogen (starch) synthase activity
GMA17_RS04350	COG0438	transferase activity, transferring glycosyl groups
GMA17_RS04360	COG0367	asparagine synthase
GMA17_RS04375	COG1215	transferase activity, transferring glycosyl groups
GMA17_RS04380	COG0438	transferase activity, transferring glycosyl groups
GMA17_RS04395	COG0686	Belongs to the AlaDH PNT family
GMA17_RS04410	COG0802	atpase or kinase
GMA17_RS04415	COG2204	response regulator
GMA17_RS04420	COG1078	dGTPase activity
GMA17_RS04425	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMA17_RS04435	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMA17_RS04440	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
GMA17_RS04445	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMA17_RS04455	COG0074	Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit
GMA17_RS04460	COG1028	Short-chain dehydrogenase reductase Sdr
GMA17_RS04475	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
GMA17_RS04480	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
GMA17_RS04485	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
GMA17_RS04490	COG0131	Imidazoleglycerol-phosphate dehydratase
GMA17_RS04500	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
GMA17_RS04505	COG0107	imidazoleglycerol-phosphate synthase activity
GMA17_RS04510	COG0140	phosphoribosyl-ATP diphosphatase activity
GMA17_RS04510	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
GMA17_RS04520	COG0101	tRNA pseudouridine synthase activity
GMA17_RS04550	COG1607	acyl-coa hydrolase
GMA17_RS04600	COG1979	alcohol dehydrogenase
GMA17_RS04605	COG2130	NADP-dependent
GMA17_RS04610	COG1309	transcriptional regulator
GMA17_RS04620	COG1012	belongs to the aldehyde dehydrogenase family
GMA17_RS04625	COG4221	oxidoreductase activity
GMA17_RS04650	COG0590	tRNA wobble adenosine to inosine editing
GMA17_RS04660	COG1529	Aldehyde oxidase and xanthine dehydrogenase
GMA17_RS04675	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
GMA17_RS04675	COG3608	succinylglutamate desuccinylase aspartoacylase
GMA17_RS04680	COG2807	transmembrane transport
GMA17_RS04685	COG2141	COG2141 Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases
GMA17_RS04700	COG4181	ATPase activity
GMA17_RS04705	COG0577	efflux transmembrane transporter activity
GMA17_RS04705	COG1136	(ABC) transporter
GMA17_RS04725	COG3279	Response regulator of the LytR AlgR family
GMA17_RS04730	COG3275	phosphorelay sensor kinase activity
GMA17_RS04735	COG1131	(ABC) transporter
GMA17_RS04760	COG1064	alcohol dehydrogenase
GMA17_RS04765	COG1902	pentaerythritol trinitrate reductase activity
GMA17_RS04770	COG0513	Belongs to the DEAD box helicase family
GMA17_RS04775	COG4942	peptidase
GMA17_RS04790	COG0798	PFAM Bile acid sodium symporter
GMA17_RS04830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMA17_RS04845	COG1131	(ABC) transporter
GMA17_RS04850	COG1131	(ABC) transporter
GMA17_RS04855	COG0842	Transport permease protein
GMA17_RS04860	COG0842	Transport permease protein
GMA17_RS04860	COG1129	ABC transporter
GMA17_RS04885	COG3129	Specifically methylates the adenine in position 1618 of 23S rRNA
GMA17_RS04890	COG1092	Specifically methylates the guanine in position 2445 (m2G2445) and the guanine in position 2069 (m7G2069) of 23S rRNA
GMA17_RS04895	COG0612	Peptidase, M16
GMA17_RS04905	COG2814	Major facilitator Superfamily
GMA17_RS04910	COG0668	transmembrane transport
GMA17_RS04915	COG1360	Flagellar Motor Protein
GMA17_RS04930	COG1187	pseudouridine synthase activity
GMA17_RS04955	COG0022	dehydrogenase e1 component
GMA17_RS04975	COG0813	purine-nucleoside phosphorylase activity
GMA17_RS04990	COG0692	Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine
GMA17_RS04995	COG1288	antiporter activity
GMA17_RS05005	COG1193	negative regulation of DNA recombination
GMA17_RS05010	COG3011	Protein conserved in bacteria
GMA17_RS05050	COG0463	Glycosyl transferase, family 2
GMA17_RS05060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GMA17_RS05100	COG1234	tRNA 3'-trailer cleavage
GMA17_RS05110	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMA17_RS05115	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
GMA17_RS05120	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
GMA17_RS05135	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
GMA17_RS05185	COG0156	8-amino-7-oxononanoate synthase activity
GMA17_RS05200	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
GMA17_RS05215	COG1393	Belongs to the ArsC family
GMA17_RS05235	COG0531	amino acid
GMA17_RS05250	COG1228	amidohydrolase
GMA17_RS05285	COG0488	(ABC) transporter
GMA17_RS05295	COG1741	Belongs to the pirin family
GMA17_RS05305	COG2388	GCN5-related N-acetyl-transferase
GMA17_RS05320	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
GMA17_RS05330	COG2304	oxidoreductase activity
GMA17_RS05345	COG4948	Mandelate Racemase Muconate Lactonizing
GMA17_RS05355	COG1028	Short-chain dehydrogenase reductase Sdr
GMA17_RS05365	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
GMA17_RS05370	COG1575	Belongs to the MenA family. Type 1 subfamily
GMA17_RS05385	COG2996	Protein conserved in bacteria
GMA17_RS05395	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
GMA17_RS05420	COG0443	Heat shock 70 kDa protein
GMA17_RS05430	COG1760	l-serine dehydratase
GMA17_RS05435	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
GMA17_RS05445	COG0564	pseudouridine synthase activity
GMA17_RS05470	COG0606	chelatase, subunit chli
GMA17_RS05485	COG1001	Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family
GMA17_RS05495	COG0037	tRNA processing
GMA17_RS05500	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GMA17_RS05505	COG0513	Belongs to the DEAD box helicase family
GMA17_RS05525	COG2972	Histidine kinase
GMA17_RS05530	COG3279	Response regulator of the LytR AlgR family
GMA17_RS05565	COG3279	Response regulator of the LytR AlgR family
GMA17_RS05570	COG3275	phosphorelay sensor kinase activity
GMA17_RS05580	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMA17_RS05605	COG1757	Na H antiporter
GMA17_RS05610	COG0450	alkyl hydroperoxide reductase
GMA17_RS05615	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
GMA17_RS05625	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GMA17_RS05630	COG2077	Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides
GMA17_RS05640	COG1674	ftsk spoiiie
GMA17_RS05655	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMA17_RS05655	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
GMA17_RS05700	COG0745	RESPONSE REGULATOR receiver
GMA17_RS05700	COG2205	protein histidine kinase activity
GMA17_RS05700	COG3292	Two component regulator propeller
GMA17_RS05715	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GMA17_RS05720	COG0778	Nitroreductase
GMA17_RS05730	COG4974	Belongs to the 'phage' integrase family
GMA17_RS05765	COG2217	Heavy metal translocating P-type atpase
GMA17_RS05770	COG2217	Heavy metal translocating P-type atpase
GMA17_RS05790	COG0531	amino acid
GMA17_RS05835	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
GMA17_RS05850	COG2207	Transcriptional regulator
GMA17_RS05855	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMA17_RS05895	COG2132	Multicopper oxidase
GMA17_RS05905	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
GMA17_RS05960	COG0531	amino acid
GMA17_RS05965	COG2608	mercury ion transmembrane transporter activity
GMA17_RS05975	COG1830	Aldolase
GMA17_RS05980	COG1301	dicarboxylic acid transport
GMA17_RS05990	COG0205	6-phosphofructokinase activity
GMA17_RS05995	COG3174	membrane
GMA17_RS06015	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GMA17_RS06035	COG2217	Heavy metal translocating P-type atpase
GMA17_RS06040	COG2814	Major facilitator Superfamily
GMA17_RS06100	COG0450	alkyl hydroperoxide reductase
GMA17_RS06105	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMA17_RS06110	COG2226	methyltransferase
GMA17_RS06130	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMA17_RS06150	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
GMA17_RS06200	COG2234	aminopeptidase activity
GMA17_RS06200	COG4935	Belongs to the peptidase S8 family
GMA17_RS06215	COG2120	A mycothiol (MSH, N-acetylcysteinyl-glucosaminyl- inositol) S-conjugate amidase, it recycles conjugated MSH to the N-acetyl cysteine conjugate (AcCys S-conjugate, a mercapturic acid) and the MSH precursor. Involved in MSH-dependent detoxification of a number of alkylating agents and antibiotics
GMA17_RS06220	COG0626	cystathionine gamma-synthase activity
GMA17_RS06230	COG1970	mechanosensitive ion channel activity
GMA17_RS06235	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
GMA17_RS06235	COG1333	cytochrome c biogenesis protein
GMA17_RS06270	COG0424	maF-like protein
GMA17_RS06280	COG0598	Magnesium transport protein CorA
GMA17_RS06305	COG1476	TRANSCRIPTIONal
GMA17_RS06340	COG0702	epimerase
GMA17_RS06350	COG0415	Belongs to the DNA photolyase family
GMA17_RS06355	COG3046	protein related to deoxyribodipyrimidine photolyase
GMA17_RS06360	COG0415	Belongs to the DNA photolyase family
GMA17_RS06375	COG0302	gtp cyclohydrolase
GMA17_RS06390	COG0386	Belongs to the glutathione peroxidase family
GMA17_RS06410	COG0415	Belongs to the DNA photolyase family
GMA17_RS06420	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
GMA17_RS06440	COG0514	ATP-dependent DNA helicase (RecQ)
GMA17_RS06445	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GMA17_RS06455	COG1678	Uncharacterized ACR, COG1678
GMA17_RS06520	COG1112	Superfamily I DNA and RNA helicases and helicase subunits
GMA17_RS06600	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GMA17_RS06605	COG1053	succinate dehydrogenase
GMA17_RS06665	COG0124	histidyl-tRNA synthetase
GMA17_RS06675	COG0584	glycerophosphoryl diester phosphodiesterase
GMA17_RS06680	COG0359	binds to the 23S rRNA
GMA17_RS06685	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
GMA17_RS06690	COG0360	Binds together with S18 to 16S ribosomal RNA
GMA17_RS06695	COG3279	Response regulator of the LytR AlgR family
GMA17_RS06700	COG1198	Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA
GMA17_RS06720	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
GMA17_RS06735	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
GMA17_RS06770	COG3250	beta-galactosidase activity
GMA17_RS06780	COG4413	Urea transporter
GMA17_RS06820	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
GMA17_RS06845	COG0488	(ABC) transporter
GMA17_RS06935	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
GMA17_RS06940	COG1120	ATPase activity
GMA17_RS06945	COG1322	Protein conserved in bacteria
GMA17_RS06955	COG1607	acyl-coa hydrolase
GMA17_RS06980	COG0230	Belongs to the bacterial ribosomal protein bL34 family
GMA17_RS06995	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMA17_RS07000	COG1388	LysM domain
GMA17_RS07000	COG0741	lytic transglycosylase activity
GMA17_RS07030	COG0254	rRNA binding
GMA17_RS07040	COG0463	Glycosyl transferase, family 2
GMA17_RS07045	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
GMA17_RS07050	COG1132	(ABC) transporter
GMA17_RS07075	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GMA17_RS07075	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
GMA17_RS07090	COG1022	Amp-dependent synthetase and ligase
GMA17_RS07100	COG1024	Enoyl-CoA hydratase
GMA17_RS07100	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMA17_RS07105	COG0183	Belongs to the thiolase family
GMA17_RS07110	COG1960	acyl-CoA dehydrogenase activity
GMA17_RS07135	COG4447	cellulose binding
GMA17_RS07140	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GMA17_RS07155	COG3278	Belongs to the heme-copper respiratory oxidase family
GMA17_RS07230	COG4263	nitrous-oxide reductase activity
GMA17_RS07235	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GMA17_RS07245	COG0589	response to stress
GMA17_RS07250	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMA17_RS07305	COG3275	phosphorelay sensor kinase activity
GMA17_RS07330	COG1252	NADH dehydrogenase
GMA17_RS07390	COG0714	Associated with various cellular activities
GMA17_RS07395	COG1721	protein (some members contain a von Willebrand factor type A (vWA) domain
GMA17_RS07405	COG0783	Belongs to the Dps family
GMA17_RS07445	COG0492	ferredoxin-NADP+ reductase activity
GMA17_RS07495	COG1012	belongs to the aldehyde dehydrogenase family
GMA17_RS07510	COG4251	negative regulation of phosphorylation
GMA17_RS07515	COG0784	Response regulator, receiver
GMA17_RS07580	COG1047	Peptidyl-prolyl cis-trans
GMA17_RS07595	COG2133	pyrroloquinoline quinone binding
GMA17_RS07600	COG0572	uridine kinase
GMA17_RS07610	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMA17_RS07615	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMA17_RS07615	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
GMA17_RS07625	COG2846	Di-iron-containing protein involved in the repair of iron-sulfur clusters
GMA17_RS07660	COG1192	Involved in chromosome partitioning
GMA17_RS07665	COG1475	DNA binding
GMA17_RS07675	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
GMA17_RS07680	COG0681	Belongs to the peptidase S26 family
GMA17_RS07710	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
GMA17_RS07720	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
GMA17_RS07730	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
GMA17_RS07750	COG0105	UTP biosynthetic process
GMA17_RS07755	COG0618	3'(2'),5'-bisphosphate nucleotidase activity
GMA17_RS07765	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GMA17_RS07780	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GMA17_RS07800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GMA17_RS07810	COG0501	Belongs to the peptidase M48B family
GMA17_RS07830	COG0517	IMP dehydrogenase activity
GMA17_RS07830	COG0516	GMP reductase activity
GMA17_RS07850	COG1730	sister chromatid segregation
GMA17_RS07870	COG0167	dihydroorotate dehydrogenase activity
GMA17_RS07875	COG2195	Cleaves the N-terminal amino acid of tripeptides
GMA17_RS07910	COG1862	Preprotein translocase
GMA17_RS07920	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
GMA17_RS07930	COG1132	(ABC) transporter
GMA17_RS07945	COG0385	Bile acid
GMA17_RS07960	COG0652	PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides
GMA17_RS07965	COG0514	ATP-dependent DNA helicase (RecQ)
GMA17_RS07970	COG0517	IMP dehydrogenase activity
GMA17_RS07970	COG0794	Belongs to the SIS family. GutQ KpsF subfamily
GMA17_RS07980	COG1137	ATPase activity
GMA17_RS07985	COG2354	Protein conserved in bacteria
GMA17_RS07990	COG1183	phosphatidylcholine synthase activity
GMA17_RS08005	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
GMA17_RS08065	COG0438	transferase activity, transferring glycosyl groups
GMA17_RS08070	COG3510	cephalosporin hydroxylase
GMA17_RS08080	COG0438	transferase activity, transferring glycosyl groups
GMA17_RS08105	COG0438	transferase activity, transferring glycosyl groups
GMA17_RS08120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GMA17_RS08120	COG0519	Catalyzes the synthesis of GMP from XMP
GMA17_RS08125	COG0367	asparagine synthase
GMA17_RS08135	COG1216	Glycosyl transferase, family 2
GMA17_RS08150	COG1215	transferase activity, transferring glycosyl groups
GMA17_RS08165	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMA17_RS08170	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
GMA17_RS08200	COG2852	Protein conserved in bacteria
GMA17_RS08225	COG0677	UDP-N-acetyl-D-mannosamine dehydrogenase activity
GMA17_RS08240	COG0488	(ABC) transporter
GMA17_RS08260	COG0653	protein targeting
GMA17_RS08290	COG1595	DNA-templated transcription, initiation
GMA17_RS08305	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMA17_RS08310	COG0463	Glycosyl transferase, family 2
GMA17_RS08325	COG0671	phosphoesterase, PA-phosphatase related
GMA17_RS08335	COG0534	Mate efflux family protein
GMA17_RS08350	COG0482	sulfurtransferase activity
GMA17_RS08355	COG2335	COG2335, Secreted and surface protein containing fasciclin-like repeats
GMA17_RS08365	COG0706	membrane insertase activity
GMA17_RS08370	COG0504	CTP synthase activity
GMA17_RS08375	COG3530	Putative quorum-sensing-regulated virulence factor
GMA17_RS08385	COG0791	NLP P60 protein
GMA17_RS08385	COG1388	LysM domain
GMA17_RS08390	COG0518	GMP synthase (glutamine-hydrolyzing) activity
GMA17_RS08390	COG0519	Catalyzes the synthesis of GMP from XMP
GMA17_RS08395	COG0076	glutamate decarboxylase activity
GMA17_RS08400	COG4365	Involved in bacillithiol (BSH) biosynthesis. May catalyze the last step of the pathway, the addition of cysteine to glucosamine malate (GlcN-Mal) to generate BSH
GMA17_RS08420	COG2239	Acts as a magnesium transporter
GMA17_RS08425	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
GMA17_RS08430	COG0552	protein localization to endoplasmic reticulum
GMA17_RS08440	COG0267	Belongs to the bacterial ribosomal protein bL33 family
GMA17_RS08445	COG0227	Belongs to the bacterial ribosomal protein bL28 family
GMA17_RS08450	COG1058	Belongs to the CinA family
GMA17_RS08450	COG1546	Belongs to the CinA family
GMA17_RS08460	COG0179	Fumarylacetoacetate (FAA) hydrolase
GMA17_RS08465	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
GMA17_RS08485	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMA17_RS08495	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
GMA17_RS08510	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMA17_RS08515	COG1506	peptidase
GMA17_RS08525	COG0326	Molecular chaperone. Has ATPase activity
GMA17_RS08575	COG1741	Belongs to the pirin family
GMA17_RS08620	COG0513	Belongs to the DEAD box helicase family
GMA17_RS08695	COG1482	cell wall glycoprotein biosynthetic process
GMA17_RS08705	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
GMA17_RS08710	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
GMA17_RS08725	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
GMA17_RS08730	COG0085	RNA polymerase activity
GMA17_RS08735	COG0222	ribosome binding
GMA17_RS08740	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
GMA17_RS08745	COG0081	regulation of translation
GMA17_RS08750	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
GMA17_RS08770	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
GMA17_RS08795	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
GMA17_RS08800	COG4974	Belongs to the 'phage' integrase family
GMA17_RS08805	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GMA17_RS08845	COG1960	acyl-CoA dehydrogenase activity
GMA17_RS08855	COG1115	amino acid carrier protein
GMA17_RS08860	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
GMA17_RS08900	COG0577	efflux transmembrane transporter activity
GMA17_RS08905	COG3876	Protein conserved in bacteria
GMA17_RS08930	COG3118	belongs to the thioredoxin family
GMA17_RS08945	COG1574	metal-dependent hydrolase with the TIM-barrel fold
GMA17_RS08960	COG2884	Cell division ATP-binding protein ftsE
GMA17_RS08970	COG1216	Glycosyl transferase, family 2
GMA17_RS09015	COG1215	transferase activity, transferring glycosyl groups
GMA17_RS09030	COG1217	gtp-binding protein TYPA
GMA17_RS09040	COG2877	3-deoxy-8-phosphooctulonate synthase activity
GMA17_RS09070	COG4452	Inner membrane protein CreD
GMA17_RS09090	COG0300	oxidoreductase activity
GMA17_RS09150	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMA17_RS09155	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMA17_RS09170	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
GMA17_RS09180	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
GMA17_RS09185	COG0134	indole-3-glycerol-phosphate synthase activity
GMA17_RS09190	COG0135	phosphoribosylanthranilate isomerase activity
GMA17_RS09195	COG0133	tryptophan synthase activity
GMA17_RS09200	COG0159	tryptophan synthase activity
GMA17_RS09215	COG4628	conserved protein (DUF2132)
GMA17_RS09225	COG0513	Belongs to the DEAD box helicase family
GMA17_RS09250	COG1127	ABC transporter
GMA17_RS09255	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
GMA17_RS09260	COG1524	type I phosphodiesterase nucleotide pyrophosphatase
GMA17_RS09270	COG0688	phosphatidylethanolamine metabolic process
GMA17_RS09275	COG4589	Belongs to the CDS family
GMA17_RS09285	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
GMA17_RS09290	COG0799	negative regulation of ribosome biogenesis
GMA17_RS09295	COG1654	Acts both as a biotin-- acetyl-CoA-carboxylase ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio- 5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon
GMA17_RS09295	COG0340	biotin-[acetyl-CoA-carboxylase] ligase activity
GMA17_RS09305	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
GMA17_RS09320	COG2170	ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity
GMA17_RS09335	COG0659	secondary active sulfate transmembrane transporter activity
GMA17_RS09340	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
GMA17_RS09345	COG1181	Belongs to the D-alanine--D-alanine ligase family
GMA17_RS09350	COG2815	serine threonine protein kinase
GMA17_RS09350	COG0515	serine threonine protein kinase
GMA17_RS09355	COG0564	pseudouridine synthase activity
GMA17_RS09360	COG3022	response to hydroperoxide
GMA17_RS09395	COG0001	glutamate-1-semialdehyde 2,1-aminomutase activity
GMA17_RS09425	COG2987	Catalyzes the conversion of urocanate to 4-imidazolone- 5-propionate
GMA17_RS09440	COG1278	Cold shock
GMA17_RS09450	COG0022	dehydrogenase e1 component
GMA17_RS09455	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMA17_RS09460	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GMA17_RS09470	COG2030	dehydratase
GMA17_RS09470	COG1012	belongs to the aldehyde dehydrogenase family
GMA17_RS09475	COG0183	Belongs to the thiolase family
GMA17_RS09480	COG2321	neutral zinc metallopeptidase
GMA17_RS09495	COG1250	3-hydroxyacyl-CoA dehydrogenase
GMA17_RS09505	COG1024	Enoyl-CoA hydratase
GMA17_RS09510	COG2151	metal-sulfur cluster biosynthetic enzyme
GMA17_RS09515	COG3396	Phenylacetate-CoA oxygenase
GMA17_RS09520	COG3460	Phenylacetate-CoA oxygenase
GMA17_RS09525	COG3396	Phenylacetate-CoA oxygenase
GMA17_RS09530	COG1018	Is involved in NO detoxification in an aerobic process, termed nitric oxide dioxygenase (NOD) reaction that utilizes O(2) and NAD(P)H to convert NO to nitrate, which protects the bacterium from various noxious nitrogen compounds. Therefore, plays a central role in the inducible response to nitrosative stress
GMA17_RS09535	COG1309	transcriptional regulator
GMA17_RS09550	COG2197	response regulator
GMA17_RS09555	COG4585	Histidine kinase
GMA17_RS09575	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
GMA17_RS09580	COG0739	heme binding
GMA17_RS09600	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
GMA17_RS09610	COG1160	GTP binding
GMA17_RS09635	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
GMA17_RS09650	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GMA17_RS09660	COG2373	Large extracellular alpha-helical protein
GMA17_RS09680	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
GMA17_RS09685	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
GMA17_RS09690	COG0563	adenylate kinase activity
GMA17_RS09695	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
GMA17_RS09700	COG0041	Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR)
GMA17_RS09725	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GMA17_RS09725	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
GMA17_RS09730	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMA17_RS09740	COG1215	transferase activity, transferring glycosyl groups
GMA17_RS09750	COG0525	valine-tRNA ligase activity
GMA17_RS09770	COG0436	Aminotransferase
GMA17_RS09775	COG0812	UDP-N-acetylmuramate dehydrogenase activity
GMA17_RS09780	COG1595	DNA-templated transcription, initiation
GMA17_RS09795	COG1216	Glycosyl transferase, family 2
GMA17_RS09805	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
GMA17_RS09810	COG0057	glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity
GMA17_RS09815	COG2205	protein histidine kinase activity
GMA17_RS09815	COG0784	Response regulator, receiver
GMA17_RS09820	COG1663	tetraacyldisaccharide 4'-kinase activity
GMA17_RS09825	COG0327	Belongs to the GTP cyclohydrolase I type 2 NIF3 family
GMA17_RS09850	COG3844	kynureninase activity
GMA17_RS09855	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
GMA17_RS09870	COG1028	Short-chain dehydrogenase reductase Sdr
GMA17_RS09880	COG0662	Cupin 2, conserved barrel domain protein
GMA17_RS09915	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMA17_RS09950	COG3340	Belongs to the peptidase S51 family
GMA17_RS09960	COG0696	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate
GMA17_RS09970	COG0427	acetyl-CoA hydrolase
GMA17_RS09980	COG2226	methyltransferase
GMA17_RS09985	COG2363	Small membrane protein
GMA17_RS09995	COG1477	protein flavinylation
GMA17_RS10010	COG2209	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GMA17_RS10020	COG2869	NQR complex catalyzes the reduction of ubiquinone-1 to ubiquinol by two successive reactions, coupled with the transport of Na( ) ions from the cytoplasm to the periplasm. NqrA to NqrE are probably involved in the second step, the conversion of ubisemiquinone to ubiquinol
GMA17_RS10025	COG1805	sodium ion transport
GMA17_RS10050	COG1012	belongs to the aldehyde dehydrogenase family
GMA17_RS10060	COG0357	Ribosomal RNA small subunit methyltransferase G
GMA17_RS10065	COG3239	Fatty acid desaturase
GMA17_RS10070	COG0436	Aminotransferase
GMA17_RS10085	COG2226	methyltransferase
GMA17_RS10095	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
GMA17_RS10105	COG0191	fructose-bisphosphate aldolase activity
GMA17_RS10110	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
GMA17_RS10115	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
GMA17_RS10120	COG1185	polyribonucleotide nucleotidyltransferase activity
GMA17_RS10135	COG2205	protein histidine kinase activity
GMA17_RS10135	COG0784	Response regulator, receiver
GMA17_RS10140	COG4999	Histidine kinase
GMA17_RS10140	COG3850	Histidine kinase
GMA17_RS10140	COG3437	response regulator, receiver
GMA17_RS10140	COG2205	protein histidine kinase activity
GMA17_RS10155	COG0345	Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline
GMA17_RS10160	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
GMA17_RS10165	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
GMA17_RS10170	COG4974	Belongs to the 'phage' integrase family
GMA17_RS10250	COG3609	addiction module antidote protein, CC2985 family
GMA17_RS10285	COG1396	sequence-specific DNA binding
GMA17_RS10410	COG3263	regulation of cellular component size
GMA17_RS10415	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
GMA17_RS10420	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
GMA17_RS10425	COG0517	IMP dehydrogenase activity
GMA17_RS10445	COG1610	YqeY-like protein
GMA17_RS10450	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
GMA17_RS10465	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
GMA17_RS10470	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GMA17_RS10480	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
GMA17_RS10485	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
GMA17_RS10490	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GMA17_RS10505	COG0275	rRNA processing
GMA17_RS10510	COG2001	Belongs to the MraZ family
GMA17_RS10515	COG2267	carboxylic ester hydrolase activity
GMA17_RS10520	COG0218	Necessary for normal cell division and for the maintenance of normal septation
GMA17_RS10525	COG1173	ABC-type dipeptide oligopeptide nickel transport systems, permease components
GMA17_RS10530	COG0793	Belongs to the peptidase S41A family
GMA17_RS10535	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
GMA17_RS10545	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMA17_RS10555	COG0791	NLP P60 protein
GMA17_RS10560	COG0658	competence protein
GMA17_RS10560	COG2333	competence protein COMEC
GMA17_RS10565	COG4232	protein-disulfide reductase activity
GMA17_RS10575	COG3104	oligopeptide transport
GMA17_RS10600	COG1253	flavin adenine dinucleotide binding
GMA17_RS10625	COG1521	Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis
GMA17_RS10675	COG1054	Belongs to the UPF0176 family
GMA17_RS10680	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMA17_RS10680	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMA17_RS10685	COG0730	response to heat
GMA17_RS10705	COG0607	Catalyzes the ATP-dependent transfer of a sulfur to tRNA to produce 4-thiouridine in position 8 of tRNAs, which functions as a near-UV photosensor. Also catalyzes the transfer of sulfur to the sulfur carrier protein ThiS, forming ThiS-thiocarboxylate. This is a step in the synthesis of thiazole, in the thiamine biosynthesis pathway. The sulfur is donated as persulfide by IscS
GMA17_RS10715	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
GMA17_RS10720	COG2226	methyltransferase
GMA17_RS10745	COG1251	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
GMA17_RS10760	COG1215	transferase activity, transferring glycosyl groups
GMA17_RS10765	COG0702	epimerase
GMA17_RS10795	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
GMA17_RS10795	COG3153	acetyltransferase
GMA17_RS10800	COG1899	peptidyl-lysine modification to peptidyl-hypusine
GMA17_RS10805	COG0010	Belongs to the arginase family
GMA17_RS10810	COG1166	arginine decarboxylase activity
GMA17_RS10820	COG1187	pseudouridine synthase activity
GMA17_RS10855	COG2081	HI0933 family
GMA17_RS10860	COG0584	glycerophosphoryl diester phosphodiesterase
GMA17_RS10870	COG1946	Acyl-CoA thioesterase
GMA17_RS10885	COG1262	PFAM Formylglycine-generating sulfatase enzyme
GMA17_RS10895	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GMA17_RS10915	COG0397	Uncharacterized ACR, YdiU/UPF0061 family
GMA17_RS10925	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
GMA17_RS10950	COG0129	dihydroxy-acid dehydratase activity
GMA17_RS10955	COG0028	Belongs to the TPP enzyme family
GMA17_RS10965	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
GMA17_RS10970	COG1171	Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short- lived. The second step is the nonenzymatic hydrolysis of the enamine imine intermediates to form 2-ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA
GMA17_RS10975	COG0753	catalase activity
GMA17_RS11000	COG0431	NADPH-dependent FMN reductase
GMA17_RS11010	COG2353	YceI-like domain
GMA17_RS11025	COG2761	dithiol-disulfide isomerase involved in polyketide biosynthesis
GMA17_RS11050	COG1063	alcohol dehydrogenase
GMA17_RS11055	COG0783	Belongs to the Dps family
GMA17_RS11065	COG1741	Belongs to the pirin family
GMA17_RS11070	COG0402	S-adenosylhomocysteine deaminase activity
GMA17_RS11075	COG0402	S-adenosylhomocysteine deaminase activity
GMA17_RS11080	COG0402	S-adenosylhomocysteine deaminase activity
GMA17_RS11085	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
GMA17_RS11140	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMA17_RS11150	COG2824	Alkylphosphonate utilization operon protein PhnA
GMA17_RS11155	COG2315	Protein conserved in bacteria
GMA17_RS11170	COG0635	Involved in the biosynthesis of porphyrin-containing compound
GMA17_RS11175	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
GMA17_RS11190	COG0463	Glycosyl transferase, family 2
GMA17_RS11225	COG2197	response regulator
GMA17_RS11230	COG4585	Histidine kinase
GMA17_RS11255	COG0643	Histidine kinase
GMA17_RS11255	COG0784	Response regulator, receiver
GMA17_RS11255	COG2198	Histidine kinase
GMA17_RS11260	COG5002	protein histidine kinase activity
GMA17_RS11270	COG3604	Transcriptional regulator
GMA17_RS11285	COG3118	belongs to the thioredoxin family
GMA17_RS11305	COG0228	four-way junction DNA binding
GMA17_RS11310	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
GMA17_RS11315	COG5002	protein histidine kinase activity
GMA17_RS11325	COG4123	Specifically methylates the adenine in position 37 of tRNA(1)(Val) (anticodon cmo5UAC)
GMA17_RS11330	COG0628	permease
GMA17_RS11350	COG0633	Ferredoxin
GMA17_RS11355	COG0492	ferredoxin-NADP+ reductase activity
GMA17_RS11365	COG0489	protein tyrosine kinase activity
GMA17_RS11380	COG0220	tRNA (guanine-N7-)-methyltransferase activity
GMA17_RS11385	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
GMA17_RS11390	COG5002	protein histidine kinase activity
GMA17_RS11395	COG0745	RESPONSE REGULATOR receiver
GMA17_RS11415	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
GMA17_RS11430	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
GMA17_RS11435	COG0463	Glycosyl transferase, family 2
GMA17_RS11455	COG1866	Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA
GMA17_RS11460	COG2363	Small membrane protein
GMA17_RS11470	COG1522	sequence-specific DNA binding
GMA17_RS11485	COG0495	leucyl-tRNA aminoacylation
GMA17_RS11490	COG2177	Part of the ABC transporter FtsEX involved in
GMA17_RS11500	COG1968	undecaprenyl-diphosphatase activity
GMA17_RS11505	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
GMA17_RS11520	COG0519	Catalyzes the synthesis of GMP from XMP
GMA17_RS11525	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
GMA17_RS11535	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
GMA17_RS11540	COG3852	Histidine kinase
GMA17_RS11555	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
GMA17_RS11570	COG1186	Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA
GMA17_RS11595	COG1646	35 carbon atoms) to the C3 hydroxyl of sn-glycerol-1-phosphate (G1P), producing heptaprenylglyceryl phosphate (HepGP). This reaction is an ether-bond-formation step in the biosynthesis of archaea-type G1P-based membrane lipids found in Bacillales
GMA17_RS11605	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
GMA17_RS11615	COG0211	Belongs to the bacterial ribosomal protein bL27 family
GMA17_RS11620	COG0261	This protein binds to 23S rRNA in the presence of protein L20
GMA17_RS11630	COG0612	Peptidase, M16
GMA17_RS11635	COG0612	Peptidase, M16
GMA17_RS11670	COG0776	regulation of translation
GMA17_RS11675	COG1530	ribonuclease E activity
GMA17_RS11695	COG0667	Aldo Keto reductase
GMA17_RS11700	COG1360	Flagellar Motor Protein
GMA17_RS11705	COG0708	Exodeoxyribonuclease III
GMA17_RS11735	COG0423	glycine-tRNA ligase activity
GMA17_RS11745	COG1040	competence protein
GMA17_RS11765	COG0436	Aminotransferase
GMA17_RS11770	COG4717	serine-type aminopeptidase activity
GMA17_RS11775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GMA17_RS11780	COG4935	Belongs to the peptidase S8 family
GMA17_RS11780	COG2234	aminopeptidase activity
GMA17_RS11785	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
GMA17_RS11790	COG1053	succinate dehydrogenase
GMA17_RS11810	COG0006	proline dipeptidase activity
GMA17_RS11820	COG3118	belongs to the thioredoxin family
GMA17_RS11830	COG1917	Cupin 2, conserved barrel domain protein
GMA17_RS11830	COG2169	Transcriptional regulator
GMA17_RS11835	COG1114	Component of the transport system for branched-chain amino acids
GMA17_RS11850	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
GMA17_RS11880	COG0719	Fe-S assembly protein
GMA17_RS11890	COG0396	ATPase activity
GMA17_RS11895	COG0719	Fe-S assembly protein
GMA17_RS11900	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
GMA17_RS11915	COG2166	iron-sulfur cluster assembly
GMA17_RS11920	COG2151	metal-sulfur cluster biosynthetic enzyme
GMA17_RS11940	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
GMA17_RS11945	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
GMA17_RS11980	COG4771	TonB-dependent receptor
GMA17_RS11985	COG0166	Belongs to the GPI family
GMA17_RS11995	COG3483	tryptophan 2,3-dioxygenase activity
GMA17_RS12005	COG3185	4-Hydroxyphenylpyruvate dioxygenase
GMA17_RS12010	COG3508	Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate
GMA17_RS12015	COG1752	Esterase of the alpha-beta hydrolase superfamily
GMA17_RS12020	COG0322	excinuclease ABC activity
GMA17_RS12025	COG0189	ligase activity
GMA17_RS12025	COG4067	protein conserved in archaea
GMA17_RS12030	COG0189	ligase activity
GMA17_RS12040	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
GMA17_RS12045	COG0739	heme binding
GMA17_RS12050	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
GMA17_RS12065	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
GMA17_RS12075	COG1066	DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function
GMA17_RS12090	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
GMA17_RS12095	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
GMA17_RS12100	COG0297	glycogen (starch) synthase activity
GMA17_RS12110	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
GMA17_RS12115	COG4206	TonB-dependent receptor
GMA17_RS12115	COG1629	transport
GMA17_RS12130	COG0355	proton-transporting ATP synthase activity, rotational mechanism
GMA17_RS12135	COG0591	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
GMA17_RS12155	COG4206	TonB-dependent receptor
GMA17_RS12165	COG2268	Band 7 protein
GMA17_RS12195	COG1381	Involved in DNA repair and RecF pathway recombination
GMA17_RS12215	COG0334	Belongs to the Glu Leu Phe Val dehydrogenases family
GMA17_RS12225	COG0626	cystathionine gamma-synthase activity
GMA17_RS12245	COG1561	YicC-like family, N-terminal region
GMA17_RS12250	COG0194	GDP metabolic process
GMA17_RS12255	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
GMA17_RS12265	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
GMA17_RS12290	COG2267	carboxylic ester hydrolase activity
GMA17_RS12315	COG0750	zinc metalloprotease
GMA17_RS12325	COG1999	signal sequence binding
GMA17_RS12355	COG4771	TonB-dependent receptor
GMA17_RS12360	COG0803	Belongs to the bacterial solute-binding protein 9 family
GMA17_RS12365	COG1121	(ABC) transporter
GMA17_RS12370	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMA17_RS12375	COG1108	ABC-type Mn2 Zn2 transport systems permease components
GMA17_RS12390	COG0484	heat shock protein binding
GMA17_RS12410	COG1418	mRNA catabolic process
GMA17_RS12415	COG1024	Enoyl-CoA hydratase
GMA17_RS12420	COG5000	phosphorelay sensor kinase activity
GMA17_RS12425	COG1981	membrane
GMA17_RS12435	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
GMA17_RS12445	COG0373	Catalyzes the NADPH-dependent reduction of glutamyl- tRNA(Glu) to glutamate 1-semialdehyde (GSA)
GMA17_RS12450	COG0181	hydroxymethylbilane synthase activity
GMA17_RS12455	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
GMA17_RS12465	COG0408	coproporphyrinogen oxidase activity
GMA17_RS12475	COG0113	porphobilinogen synthase activity
GMA17_RS12485	COG1253	flavin adenine dinucleotide binding
GMA17_RS12580	COG1774	PSP1 C-terminal conserved region
GMA17_RS12585	COG0739	heme binding
GMA17_RS12585	COG1196	nuclear chromosome segregation
GMA17_RS12585	COG0741	lytic transglycosylase activity
GMA17_RS12590	COG0535	radical SAM domain protein
GMA17_RS12600	COG0826	peptidase U32
GMA17_RS12610	COG0468	Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage
GMA17_RS12645	COG0180	Tryptophanyl-tRNA synthetase
GMA17_RS12650	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
GMA17_RS12650	COG0758	DNA mediated transformation
GMA17_RS12660	COG2827	Endonuclease containing a URI domain
GMA17_RS12665	COG1607	acyl-coa hydrolase
GMA17_RS12720	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
GMA17_RS12725	COG0756	dUTP diphosphatase activity
GMA17_RS12740	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
GMA17_RS12745	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
GMA17_RS12755	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GMA17_RS12760	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
GMA17_RS12765	COG0636	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
GMA17_RS12770	COG0356	it plays a direct role in the translocation of protons across the membrane
GMA17_RS12815	COG0859	PFAM glycosyl transferase family 9
GMA17_RS12825	COG0035	Catalyzes the conversion of uracil and 5-phospho-alpha- D-ribose 1-diphosphate (PRPP) to UMP and diphosphate
GMA17_RS12840	COG0151	Belongs to the GarS family
GMA17_RS12865	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMA17_RS12870	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
GMA17_RS12925	COG2089	acid synthase
GMA17_RS12930	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMA17_RS12930	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
GMA17_RS12940	COG1083	cytidylyl-transferase
GMA17_RS12945	COG0399	UDP-4-amino-4-deoxy-L-arabinose aminotransferase
GMA17_RS12950	COG1086	Polysaccharide biosynthesis protein
GMA17_RS12965	COG0529	Catalyzes the synthesis of activated sulfate
GMA17_RS12990	COG1209	Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis
GMA17_RS13015	COG4942	peptidase
GMA17_RS13020	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
GMA17_RS13030	COG0741	lytic transglycosylase activity
GMA17_RS13030	COG1388	LysM domain
GMA17_RS13035	COG0126	phosphoglycerate kinase activity
GMA17_RS13040	COG0470	DNA polymerase III
GMA17_RS13055	COG0445	tRNA wobble uridine modification
GMA17_RS13060	COG0319	Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA
GMA17_RS13070	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GMA17_RS13100	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
GMA17_RS13110	COG1539	Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin
GMA17_RS13135	COG0557	exoribonuclease II activity
GMA17_RS13155	COG2153	protein acetylation
GMA17_RS13165	COG0793	Belongs to the peptidase S41A family
GMA17_RS13170	COG0594	ribonuclease P activity
GMA17_RS13185	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
GMA17_RS13195	COG0471	metal ion transport
GMA17_RS13195	COG3273	potassium ion transport
GMA17_RS13205	COG0481	GTPase activity
GMA17_RS13220	COG2234	aminopeptidase activity
GMA17_RS13235	COG4591	ABC-type transport system involved in lipoprotein release permease component
GMA17_RS13240	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
GMA17_RS13245	COG0346	lactoylglutathione lyase activity
GMA17_RS13260	COG3645	SOS response
GMA17_RS13265	COG1002	Type II restriction enzyme, methylase subunits
GMA17_RS13280	COG4771	TonB-dependent receptor
GMA17_RS13290	COG0823	Involved in the tonB-independent uptake of proteins
GMA17_RS13290	COG1506	peptidase
GMA17_RS13290	COG4946	Tricorn protease homolog
GMA17_RS13335	COG3291	Pkd domain containing protein
GMA17_RS13350	COG1752	Esterase of the alpha-beta hydrolase superfamily
GMA17_RS13380	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
GMA17_RS13390	COG0333	Belongs to the bacterial ribosomal protein bL32 family
GMA17_RS13395	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMA17_RS13400	COG0511	ligase activity, forming carbon-carbon bonds
GMA17_RS13405	COG0439	Biotin carboxylase
GMA17_RS13420	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
GMA17_RS13445	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
GMA17_RS13450	COG1970	mechanosensitive ion channel activity
GMA17_RS13455	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
GMA17_RS13460	COG1435	thymidine kinase activity
GMA17_RS13470	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
GMA17_RS13480	COG1573	uracil-dna glycosylase
GMA17_RS13505	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
GMA17_RS13505	COG4199	Single-strand DNA-specific exonuclease, C terminal domain
GMA17_RS13510	COG3047	cAMP biosynthetic process
GMA17_RS13510	COG2885	chlorophyll binding
GMA17_RS13530	COG2908	Hydrolyzes the pyrophosphate bond of UDP-2,3- diacylglucosamine to yield 2,3-diacylglucosamine 1-phosphate (lipid X) and UMP by catalyzing the attack of water at the alpha-P atom. Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
GMA17_RS13535	COG0720	synthase
GMA17_RS13570	COG2205	protein histidine kinase activity
GMA17_RS13570	COG3850	Histidine kinase
GMA17_RS13570	COG4999	Histidine kinase
GMA17_RS13570	COG3437	response regulator, receiver
GMA17_RS13575	COG0784	Response regulator, receiver
GMA17_RS13575	COG2205	protein histidine kinase activity
GMA17_RS13590	COG0210	DNA helicase
GMA17_RS13600	COG0156	8-amino-7-oxononanoate synthase activity
GMA17_RS13605	COG1074	ATP-dependent DNA helicase activity
GMA17_RS13620	COG0352	thiamine-phosphate diphosphorylase activity
GMA17_RS13620	COG0351	phosphomethylpyrimidine kinase
GMA17_RS13630	COG3341	Caulimovirus viroplasmin
GMA17_RS13630	COG0328	RNA-DNA hybrid ribonuclease activity
GMA17_RS13635	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
GMA17_RS13640	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GMA17_RS13645	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMA17_RS13650	COG0571	ribonuclease III activity
GMA17_RS13660	COG0469	pyruvate kinase activity
GMA17_RS13665	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
GMA17_RS13670	COG0702	epimerase
GMA17_RS13675	COG2954	triphosphatase activity
GMA17_RS13685	COG4953	penicillin-binding protein 1C
GMA17_RS13690	COG2329	Antibiotic biosynthesis monooxygenase
GMA17_RS13695	COG3361	conserved protein (COG2071)
GMA17_RS13705	COG1446	asparaginase
GMA17_RS13710	COG1012	belongs to the aldehyde dehydrogenase family
GMA17_RS13720	COG4221	oxidoreductase activity
GMA17_RS13725	COG0714	Associated with various cellular activities
GMA17_RS13740	COG2304	oxidoreductase activity
GMA17_RS13745	COG2304	oxidoreductase activity
GMA17_RS13770	COG0659	secondary active sulfate transmembrane transporter activity
GMA17_RS13775	COG0288	reversible hydration of carbon dioxide
GMA17_RS13785	COG4206	TonB-dependent receptor
GMA17_RS13820	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
GMA17_RS13830	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMA17_RS13840	COG1538	Outer membrane efflux protein
GMA17_RS13860	COG0300	oxidoreductase activity
GMA17_RS13880	COG1652	LysM domain
GMA17_RS13895	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
GMA17_RS13930	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GMA17_RS13960	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMA17_RS13965	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GMA17_RS13990	COG0842	Transport permease protein
GMA17_RS13995	COG1131	(ABC) transporter
GMA17_RS14010	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
GMA17_RS14020	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
GMA17_RS14035	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
GMA17_RS14040	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
GMA17_RS14070	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
GMA17_RS14080	COG3590	peptidase
GMA17_RS14105	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
GMA17_RS14110	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
GMA17_RS14125	COG1845	cytochrome c oxidase, subunit III
GMA17_RS14135	COG4548	von Willebrand factor, type A
GMA17_RS14140	COG0714	Associated with various cellular activities
GMA17_RS14145	COG3256	nitric oxide reductase
GMA17_RS14150	COG2010	Cytochrome c
GMA17_RS14165	COG0095	Lipoate-protein ligase
GMA17_RS14180	COG1396	sequence-specific DNA binding
GMA17_RS14195	COG0629	single-stranded DNA binding
GMA17_RS14205	COG1528	Iron-storage protein
GMA17_RS14210	COG2076	Multidrug Resistance protein
GMA17_RS14215	COG0697	spore germination
GMA17_RS14220	COG0123	including yeast histone deacetylase and acetoin utilization protein
GMA17_RS14230	COG2183	response to ionizing radiation
GMA17_RS14240	COG3015	lipoprotein NlpE involved in copper resistance
GMA17_RS14245	COG2885	chlorophyll binding
GMA17_RS14260	COG0143	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMA17_RS14260	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
GMA17_RS14265	COG1619	proteins homologs of microcin C7 resistance protein MccF
GMA17_RS14290	COG0792	nuclease activity
GMA17_RS14300	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
GMA17_RS14310	COG0158	D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1
GMA17_RS14320	COG0527	aspartate kinase activity
GMA17_RS14345	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
GMA17_RS14350	COG2239	Acts as a magnesium transporter
GMA17_RS14355	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
GMA17_RS14370	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
GMA17_RS14380	COG0196	riboflavin kinase activity
GMA17_RS14395	COG0193	aminoacyl-tRNA hydrolase activity
GMA17_RS14400	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
GMA17_RS14405	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
GMA17_RS14470	COG0582	viral genome integration into host DNA
GMA17_RS14530	COG1115	amino acid carrier protein
GMA17_RS14540	COG1028	Short-chain dehydrogenase reductase Sdr
GMA17_RS14545	COG0697	spore germination
GMA17_RS14555	COG1502	Catalyzes the reversible phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol
GMA17_RS14560	COG0668	transmembrane transport
GMA17_RS14575	COG3409	Peptidoglycan-binding domain 1 protein
GMA17_RS14575	COG0793	Belongs to the peptidase S41A family
GMA17_RS14610	COG3275	phosphorelay sensor kinase activity
GMA17_RS14615	COG3279	Response regulator of the LytR AlgR family
GMA17_RS14625	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
GMA17_RS14625	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
GMA17_RS14640	COG4771	TonB-dependent receptor
GMA17_RS14645	COG0232	Belongs to the dGTPase family. Type 2 subfamily
GMA17_RS14650	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
GMA17_RS14685	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
GMA17_RS14705	COG1309	transcriptional regulator
GMA17_RS14725	COG0567	Dehydrogenase, E1 component
GMA17_RS14730	COG0508	dehydrogenase complex catalyzes the overall conversion of
GMA17_RS14735	COG2197	response regulator
GMA17_RS14775	COG0084	hydrolase, TatD family'
GMA17_RS14780	COG0252	asparaginase activity
GMA17_RS14790	COG0811	peptide transport
GMA17_RS14820	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
GMA17_RS14825	COG0017	Asparaginyl-tRNA synthetase
GMA17_RS14840	COG0233	cytoplasmic translational termination
GMA17_RS14845	COG0528	UMP kinase activity
GMA17_RS14850	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
GMA17_RS14855	COG0052	Belongs to the universal ribosomal protein uS2 family
GMA17_RS14860	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
GMA17_RS14865	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
GMA17_RS14880	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMA17_RS14880	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
GMA17_RS14885	COG1446	asparaginase
GMA17_RS14890	COG4242	Belongs to the peptidase S51 family
GMA17_RS14895	COG0189	ligase activity
GMA17_RS14895	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
GMA17_RS14905	COG1446	asparaginase
GMA17_RS14915	COG3537	Alpha-1,2-mannosidase
GMA17_RS14920	COG3525	Glycosyl hydrolase, family 20, catalytic domain
GMA17_RS14925	COG3142	Participates in the control of copper homeostasis
GMA17_RS14940	COG1408	metallophosphoesterase
GMA17_RS14945	COG3118	belongs to the thioredoxin family
GMA17_RS14965	COG0589	response to stress
GMA17_RS14970	COG0779	Required for maturation of 30S ribosomal subunits
GMA17_RS14975	COG0195	Participates in both transcription termination and antitermination
GMA17_RS14975	COG2251	uridine kinase activity
GMA17_RS14980	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
GMA17_RS14995	COG0437	4 iron, 4 sulfur cluster binding
GMA17_RS15000	COG0052	Belongs to the universal ribosomal protein uS2 family
GMA17_RS15020	COG1622	oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor
GMA17_RS15025	COG0843	Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1- 3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B
GMA17_RS15030	COG2255	four-way junction helicase activity
GMA17_RS15035	COG2124	cytochrome p450
GMA17_RS15040	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
GMA17_RS15050	COG0632	four-way junction helicase activity
GMA17_RS15060	COG0509	glycine decarboxylation via glycine cleavage system
GMA17_RS15085	COG0109	protoheme IX farnesyltransferase activity
GMA17_RS15090	COG1845	cytochrome c oxidase, subunit III
GMA17_RS15095	COG1845	cytochrome c oxidase, subunit III
GMA17_RS15110	COG1999	signal sequence binding
GMA17_RS15115	COG2322	membrane
GMA17_RS15130	COG1136	(ABC) transporter
GMA17_RS15135	COG1136	(ABC) transporter
GMA17_RS15135	COG0577	efflux transmembrane transporter activity
GMA17_RS15140	COG0577	efflux transmembrane transporter activity
GMA17_RS15140	COG1136	(ABC) transporter
GMA17_RS15145	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
GMA17_RS15160	COG0668	transmembrane transport
GMA17_RS15180	COG3275	phosphorelay sensor kinase activity
GMA17_RS15185	COG3279	Response regulator of the LytR AlgR family
GMA17_RS15190	COG0663	COG0663 Carbonic anhydrases acetyltransferases, isoleucine patch superfamily
GMA17_RS15195	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
GMA17_RS15210	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
GMA17_RS15215	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
GMA17_RS15225	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
GMA17_RS15235	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
GMA17_RS15240	COG0596	Alpha beta hydrolase
GMA17_RS15245	COG1950	PFAM Membrane protein of
GMA17_RS15250	COG0544	peptidyl-prolyl cis-trans isomerase activity
GMA17_RS15260	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
GMA17_RS15275	COG0828	Belongs to the bacterial ribosomal protein bS21 family
GMA17_RS15285	COG1428	Deoxynucleoside kinase
GMA17_RS15310	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
GMA17_RS15345	COG1408	metallophosphoesterase
GMA17_RS15365	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
GMA17_RS15420	COG2814	Major facilitator Superfamily