locus-tag	class	description
BLTE_RS00010	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BLTE_RS00020	COG4974	Belongs to the 'phage' integrase family
BLTE_RS00025	COG0825	malonyl-CoA metabolic process
BLTE_RS00030	COG3034	peptidoglycan biosynthetic process
BLTE_RS00040	COG1040	competence protein
BLTE_RS00045	COG2226	methyltransferase
BLTE_RS00060	COG0494	nUDIX hydrolase
BLTE_RS00065	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BLTE_RS00070	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLTE_RS00075	COG0653	protein targeting
BLTE_RS00080	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BLTE_RS00095	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BLTE_RS00105	COG0527	aspartate kinase activity
BLTE_RS00115	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BLTE_RS00120	COG2890	protein-(glutamine-N5) methyltransferase activity
BLTE_RS00135	COG0542	response to heat
BLTE_RS00155	COG0739	heme binding
BLTE_RS00215	COG1960	acyl-CoA dehydrogenase activity
BLTE_RS00220	COG0009	L-threonylcarbamoyladenylate synthase
BLTE_RS00240	COG1083	cytidylyl-transferase
BLTE_RS00245	COG3959	Transketolase, thiamine diphosphate binding domain
BLTE_RS00255	COG2089	acid synthase
BLTE_RS00260	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS00265	COG1012	belongs to the aldehyde dehydrogenase family
BLTE_RS00270	COG0438	transferase activity, transferring glycosyl groups
BLTE_RS00275	COG0367	asparagine synthase
BLTE_RS00285	COG1132	(ABC) transporter
BLTE_RS00295	COG2089	acid synthase
BLTE_RS00305	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BLTE_RS00315	COG1086	Polysaccharide biosynthesis protein
BLTE_RS00330	COG0210	DNA helicase
BLTE_RS00335	COG2264	protein methyltransferase activity
BLTE_RS00345	COG0277	FAD linked oxidase domain protein
BLTE_RS00370	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BLTE_RS00375	COG0114	fumarate hydratase activity
BLTE_RS00390	COG0330	HflC and HflK could
BLTE_RS00395	COG0330	HflC and HflK could
BLTE_RS00405	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BLTE_RS00415	COG0560	Phosphoserine phosphatase
BLTE_RS00420	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BLTE_RS00425	COG0028	Belongs to the TPP enzyme family
BLTE_RS00430	COG0440	acetolactate synthase activity
BLTE_RS00435	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BLTE_RS00450	COG2192	nodulation
BLTE_RS00465	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BLTE_RS00490	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BLTE_RS00500	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLTE_RS00505	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BLTE_RS00515	COG0639	Hydrolyzes diadenosine 5',5'''-P1,P4-tetraphosphate to yield ADP
BLTE_RS00535	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BLTE_RS00545	COG0489	protein tyrosine kinase activity
BLTE_RS00545	COG3206	protein involved in exopolysaccharide biosynthesis
BLTE_RS00560	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BLTE_RS00565	COG0459	protein refolding
BLTE_RS00575	COG4178	(ABC) transporter
BLTE_RS00585	COG0463	Glycosyl transferase, family 2
BLTE_RS00595	COG0045	succinate-CoA ligase (ADP-forming) activity
BLTE_RS00595	COG1042	CoA-binding domain protein
BLTE_RS00595	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLTE_RS00605	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BLTE_RS00610	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BLTE_RS00620	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BLTE_RS00625	COG3001	Fructosamine kinase
BLTE_RS00670	COG4136	ATPase activity
BLTE_RS00675	COG4135	transport system, permease component
BLTE_RS00680	COG4134	Bacterial extracellular solute-binding protein
BLTE_RS00690	COG0512	Glutamine amidotransferase of anthranilate synthase
BLTE_RS00690	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLTE_RS00720	COG0590	tRNA wobble adenosine to inosine editing
BLTE_RS00725	COG1187	pseudouridine synthase activity
BLTE_RS00730	COG0742	ribosomal rna small subunit methyltransferase
BLTE_RS00745	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BLTE_RS00750	COG0604	alcohol dehydrogenase
BLTE_RS00760	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BLTE_RS00765	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BLTE_RS00775	COG2226	methyltransferase
BLTE_RS00780	COG0156	8-amino-7-oxononanoate synthase activity
BLTE_RS00790	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BLTE_RS00805	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLTE_RS00810	COG2204	response regulator
BLTE_RS00820	COG0124	histidyl-tRNA synthetase
BLTE_RS00840	COG0745	RESPONSE REGULATOR receiver
BLTE_RS00845	COG2030	dehydratase
BLTE_RS00850	COG0196	riboflavin kinase activity
BLTE_RS00860	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BLTE_RS00875	COG0612	Peptidase, M16
BLTE_RS00880	COG0612	Peptidase, M16
BLTE_RS00890	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BLTE_RS00895	COG0509	glycine decarboxylation via glycine cleavage system
BLTE_RS00900	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLTE_RS00905	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BLTE_RS00915	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BLTE_RS00940	COG1196	nuclear chromosome segregation
BLTE_RS00955	COG1194	a g-specific adenine glycosylase
BLTE_RS00965	COG2217	Heavy metal translocating P-type atpase
BLTE_RS01025	COG3387	PFAM Glycoside hydrolase 15-related
BLTE_RS01030	COG1877	trehalose-phosphatase activity
BLTE_RS01035	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BLTE_RS01040	COG4221	oxidoreductase activity
BLTE_RS01050	COG0644	oxidoreductase
BLTE_RS01055	COG2211	Major facilitator Superfamily
BLTE_RS01060	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BLTE_RS01080	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BLTE_RS01085	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BLTE_RS01090	COG1429	ligase activity, forming nitrogen-metal bonds
BLTE_RS01095	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BLTE_RS01130	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BLTE_RS01165	COG1850	ribulose-bisphosphate carboxylase activity
BLTE_RS01180	COG1562	ergosterol biosynthetic process
BLTE_RS01185	COG1233	COG1233 Phytoene dehydrogenase and related
BLTE_RS01195	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BLTE_RS01205	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BLTE_RS01215	COG0142	geranyltranstransferase activity
BLTE_RS01220	COG1063	alcohol dehydrogenase
BLTE_RS01225	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BLTE_RS01230	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BLTE_RS01235	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BLTE_RS01270	COG1009	NADH ubiquinone oxidoreductase subunit 5 chain L Multisubunit Na H antiporter, MnhA subunit
BLTE_RS01270	COG2111	Na H antiporter
BLTE_RS01275	COG1006	Multisubunit Na H antiporter MnhC subunit
BLTE_RS01280	COG0651	ATP synthesis coupled electron transport
BLTE_RS01285	COG1863	multisubunit Na H antiporter MnhE subunit
BLTE_RS01290	COG2212	antiporter activity
BLTE_RS01295	COG1320	monovalent cation:proton antiporter activity
BLTE_RS01305	COG2890	protein-(glutamine-N5) methyltransferase activity
BLTE_RS01330	COG0589	response to stress
BLTE_RS01340	COG3300	MHYT domain
BLTE_RS01340	COG5001	Diguanylate cyclase
BLTE_RS01350	COG0800	Aldolase
BLTE_RS01375	COG2151	metal-sulfur cluster biosynthetic enzyme
BLTE_RS01390	COG0515	serine threonine protein kinase
BLTE_RS01390	COG2815	serine threonine protein kinase
BLTE_RS01395	COG0631	protein serine/threonine phosphatase activity
BLTE_RS01415	COG3023	N-Acetylmuramoyl-L-alanine amidase
BLTE_RS01420	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BLTE_RS01425	COG2001	Belongs to the MraZ family
BLTE_RS01430	COG0275	rRNA processing
BLTE_RS01445	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BLTE_RS01450	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLTE_RS01455	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BLTE_RS01465	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLTE_RS01470	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BLTE_RS01485	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BLTE_RS01490	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BLTE_RS01495	COG0849	cell division
BLTE_RS01500	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BLTE_RS01510	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BLTE_RS01520	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BLTE_RS01530	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BLTE_RS01535	COG1278	Cold shock
BLTE_RS01565	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BLTE_RS01570	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS01575	COG0006	proline dipeptidase activity
BLTE_RS01580	COG4095	Psort location CytoplasmicMembrane, score
BLTE_RS01585	COG1278	Cold shock
BLTE_RS01610	COG2003	Belongs to the UPF0758 family
BLTE_RS01615	COG0024	Methionine aminopeptidase
BLTE_RS01630	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BLTE_RS01650	COG1376	ErfK ybiS ycfS ynhG family protein
BLTE_RS01660	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BLTE_RS01675	COG1013	pyruvate-flavodoxin oxidoreductase activity
BLTE_RS01680	COG0674	pyruvate-flavodoxin oxidoreductase activity
BLTE_RS01680	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BLTE_RS01710	COG0559	Belongs to the binding-protein-dependent transport system permease family
BLTE_RS01720	COG0683	leucine binding
BLTE_RS01725	COG2050	protein possibly involved in aromatic compounds catabolism
BLTE_RS01760	COG1218	3'(2'),5'-bisphosphate nucleotidase
BLTE_RS01770	COG2198	Histidine kinase
BLTE_RS01770	COG0784	Response regulator, receiver
BLTE_RS01770	COG0643	Histidine kinase
BLTE_RS01780	COG2201	protein-glutamate methylesterase activity
BLTE_RS01785	COG2201	protein-glutamate methylesterase activity
BLTE_RS01790	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BLTE_RS01800	COG0745	RESPONSE REGULATOR receiver
BLTE_RS01845	COG1846	Transcriptional regulator
BLTE_RS01865	COG2968	Membrane
BLTE_RS01885	COG1561	YicC-like family, N-terminal region
BLTE_RS01890	COG0194	GDP metabolic process
BLTE_RS01905	COG3300	MHYT domain
BLTE_RS01905	COG5001	Diguanylate cyclase
BLTE_RS01910	COG0840	transmembrane signaling receptor activity
BLTE_RS01920	COG2030	dehydratase
BLTE_RS01925	COG0012	GTP binding
BLTE_RS01930	COG0193	aminoacyl-tRNA hydrolase activity
BLTE_RS01935	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BLTE_RS01945	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BLTE_RS01975	COG0322	excinuclease ABC activity
BLTE_RS01980	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BLTE_RS01990	COG0314	molybdopterin synthase activity
BLTE_RS02005	COG1846	Transcriptional regulator
BLTE_RS02010	COG0745	RESPONSE REGULATOR receiver
BLTE_RS02015	COG2205	protein histidine kinase activity
BLTE_RS02020	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS02025	COG0463	Glycosyl transferase, family 2
BLTE_RS02035	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BLTE_RS02060	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BLTE_RS02075	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BLTE_RS02085	COG0795	lipopolysaccharide-transporting ATPase activity
BLTE_RS02090	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BLTE_RS02115	COG0488	(ABC) transporter
BLTE_RS02120	COG0297	glycogen (starch) synthase activity
BLTE_RS02130	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BLTE_RS02135	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BLTE_RS02155	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BLTE_RS02160	COG0408	coproporphyrinogen oxidase activity
BLTE_RS02170	COG0617	tRNA 3'-terminal CCA addition
BLTE_RS02180	COG0494	nUDIX hydrolase
BLTE_RS02190	COG0714	Associated with various cellular activities
BLTE_RS02220	COG1253	flavin adenine dinucleotide binding
BLTE_RS02230	COG0546	phosphoglycolate phosphatase activity
BLTE_RS02235	COG0154	amidase activity
BLTE_RS02240	COG0598	Magnesium transport protein CorA
BLTE_RS02250	COG1376	ErfK ybiS ycfS ynhG family protein
BLTE_RS02255	COG1408	metallophosphoesterase
BLTE_RS02260	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BLTE_RS02290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BLTE_RS02300	COG3447	MASE1 domain protein
BLTE_RS02300	COG5001	Diguanylate cyclase
BLTE_RS02300	COG5002	protein histidine kinase activity
BLTE_RS02305	COG0328	RNA-DNA hybrid ribonuclease activity
BLTE_RS02310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BLTE_RS02315	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BLTE_RS02320	COG0469	pyruvate kinase activity
BLTE_RS02340	COG0632	four-way junction helicase activity
BLTE_RS02350	COG3609	addiction module antidote protein, CC2985 family
BLTE_RS02360	COG2255	four-way junction helicase activity
BLTE_RS02375	COG0824	Thioesterase
BLTE_RS02405	COG0848	biopolymer transport protein
BLTE_RS02415	COG0823	Involved in the tonB-independent uptake of proteins
BLTE_RS02430	COG1278	Cold shock
BLTE_RS02445	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS02450	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BLTE_RS02455	COG2885	chlorophyll binding
BLTE_RS02465	COG0037	tRNA processing
BLTE_RS02470	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLTE_RS02480	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BLTE_RS02490	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BLTE_RS02505	COG4948	Mandelate Racemase Muconate Lactonizing
BLTE_RS02515	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BLTE_RS02520	COG1127	ABC transporter
BLTE_RS02525	COG3218	ABC-type transport auxiliary lipoprotein component
BLTE_RS02525	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BLTE_RS02530	COG3218	ABC-type transport auxiliary lipoprotein component
BLTE_RS02530	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BLTE_RS02555	COG0633	Ferredoxin
BLTE_RS02560	COG0492	ferredoxin-NADP+ reductase activity
BLTE_RS02600	COG3768	UPF0283 membrane protein
BLTE_RS02605	COG3106	COG3106 Predicted ATPase
BLTE_RS02615	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLTE_RS02620	COG0542	response to heat
BLTE_RS02625	COG5443	negative regulation of bacterial-type flagellum assembly
BLTE_RS02655	COG1706	bacterial-type flagellum-dependent cell motility
BLTE_RS02675	COG0667	Aldo Keto reductase
BLTE_RS02680	COG1064	alcohol dehydrogenase
BLTE_RS02695	COG4786	Flagellar basal body rod
BLTE_RS02700	COG4786	Flagellar basal body rod
BLTE_RS02730	COG1338	Plays a role in the flagellum-specific transport system
BLTE_RS02740	COG1815	bacterial-type flagellum-dependent cell motility
BLTE_RS02745	COG1558	bacterial-type flagellum-dependent cell motility
BLTE_RS02750	COG1677	Flagellar hook-basal body complex protein FliE
BLTE_RS02755	COG1987	bacterial-type flagellum assembly
BLTE_RS02760	COG1684	flagellar biosynthetic protein fliR
BLTE_RS02765	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLTE_RS02785	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BLTE_RS02805	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BLTE_RS02810	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BLTE_RS02815	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BLTE_RS02820	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BLTE_RS02830	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLTE_RS02840	COG0047	phosphoribosylformylglycinamidine synthase activity
BLTE_RS02845	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BLTE_RS02850	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BLTE_RS02860	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BLTE_RS02880	COG1984	allophanate hydrolase subunit 2
BLTE_RS02885	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BLTE_RS02895	COG1920	GTP binding
BLTE_RS02900	COG3191	aminopeptidase activity
BLTE_RS02905	COG2133	pyrroloquinoline quinone binding
BLTE_RS02915	COG0785	Cytochrome C biogenesis protein
BLTE_RS02950	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BLTE_RS02970	COG1309	transcriptional regulator
BLTE_RS02980	COG1131	(ABC) transporter
BLTE_RS03005	COG3932	Exopolysaccharide synthesis, ExoD
BLTE_RS03010	COG5425	PFAM Usg family protein
BLTE_RS03020	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS03025	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BLTE_RS03030	COG0459	protein refolding
BLTE_RS03045	COG2308	Evidence 4 Homologs of previously reported genes of
BLTE_RS03050	COG1058	Belongs to the CinA family
BLTE_RS03050	COG1546	Belongs to the CinA family
BLTE_RS03060	COG0577	efflux transmembrane transporter activity
BLTE_RS03060	COG1136	(ABC) transporter
BLTE_RS03065	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS03080	COG1696	Membrane protein involved in D-alanine export
BLTE_RS03145	COG0439	Biotin carboxylase
BLTE_RS03160	COG1116	anion transmembrane transporter activity
BLTE_RS03165	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLTE_RS03175	COG1496	oxidoreductase activity
BLTE_RS03185	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLTE_RS03200	COG0835	chemotaxis
BLTE_RS03205	COG2201	protein-glutamate methylesterase activity
BLTE_RS03215	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BLTE_RS03225	COG2198	Histidine kinase
BLTE_RS03225	COG0643	Histidine kinase
BLTE_RS03225	COG0784	Response regulator, receiver
BLTE_RS03230	COG1192	Involved in chromosome partitioning
BLTE_RS03235	COG0745	RESPONSE REGULATOR receiver
BLTE_RS03240	COG0840	transmembrane signaling receptor activity
BLTE_RS03255	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BLTE_RS03280	COG4716	Myosin-crossreactive antigen
BLTE_RS03300	COG1902	pentaerythritol trinitrate reductase activity
BLTE_RS03305	COG1309	transcriptional regulator
BLTE_RS03345	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BLTE_RS03345	COG1918	ferrous iron import across plasma membrane
BLTE_RS03350	COG1918	ferrous iron import across plasma membrane
BLTE_RS03370	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BLTE_RS03380	COG0640	Transcriptional regulator
BLTE_RS03390	COG0785	Cytochrome C biogenesis protein
BLTE_RS03405	COG2010	Cytochrome c
BLTE_RS03410	COG3258	Cytochrome c
BLTE_RS03425	COG0737	Belongs to the 5'-nucleotidase family
BLTE_RS03430	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLTE_RS03445	COG0446	pyridine nucleotide-disulphide oxidoreductase
BLTE_RS03450	COG0446	pyridine nucleotide-disulphide oxidoreductase
BLTE_RS03460	COG0310	cobalt ion transport
BLTE_RS03490	COG1607	acyl-coa hydrolase
BLTE_RS03520	COG0534	Mate efflux family protein
BLTE_RS03550	COG4771	TonB-dependent receptor
BLTE_RS03590	COG2207	Transcriptional regulator
BLTE_RS03595	COG2226	methyltransferase
BLTE_RS03610	COG0438	transferase activity, transferring glycosyl groups
BLTE_RS03620	COG1272	protein, Hemolysin III
BLTE_RS03640	COG3237	CsbD-like
BLTE_RS03655	COG5487	UPF0391 membrane protein
BLTE_RS03660	COG2963	transposase activity
BLTE_RS03665	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS03670	COG4372	Transposase
BLTE_RS03680	COG1278	Cold shock
BLTE_RS03685	COG1278	Cold shock
BLTE_RS03700	COG3004	Na( ) H( ) antiporter that extrudes sodium in exchange for external protons
BLTE_RS03710	COG4372	Transposase
BLTE_RS03715	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS03720	COG2963	transposase activity
BLTE_RS03760	COG4691	Plasmid stability protein
BLTE_RS03845	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLTE_RS03855	COG4566	intracellular signal transduction
BLTE_RS03860	COG4191	Histidine kinase
BLTE_RS03865	COG1122	ATPase activity
BLTE_RS03870	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BLTE_RS03875	COG1268	BioY protein
BLTE_RS03880	COG0151	Belongs to the GarS family
BLTE_RS03895	COG1968	undecaprenyl-diphosphatase activity
BLTE_RS03900	COG0268	Binds directly to 16S ribosomal RNA
BLTE_RS03905	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BLTE_RS03915	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BLTE_RS03935	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLTE_RS03940	COG0564	pseudouridine synthase activity
BLTE_RS04130	COG0507	A helicase nuclease that prepares dsDNA breaks (DSB) for recombinational DNA repair. Binds to DSBs and unwinds DNA via a highly rapid and processive ATP-dependent bidirectional helicase activity. Unwinds dsDNA until it encounters a Chi (crossover hotspot instigator) sequence from the 3' direction. Cuts ssDNA a few nucleotides 3' to the Chi site. The properties and activities of the enzyme are changed at Chi. The Chi-altered holoenzyme produces a long 3'-ssDNA overhang and facilitates RecA-binding to the ssDNA for homologous DNA recombination and repair. Holoenzyme degrades any linearized DNA that is unable to undergo homologous recombination. In the holoenzyme this subunit has ssDNA-dependent ATPase and 5'-3' helicase activity. When added to pre-assembled RecBC greatly stimulates nuclease activity and augments holoenzyme processivity. Negatively regulates the RecA-loading ability of RecBCD
BLTE_RS04145	COG1525	nuclease
BLTE_RS04150	COG1078	dGTPase activity
BLTE_RS04275	COG0446	pyridine nucleotide-disulphide oxidoreductase
BLTE_RS04280	COG2863	cytochrome
BLTE_RS04295	COG1396	sequence-specific DNA binding
BLTE_RS04305	COG1522	sequence-specific DNA binding
BLTE_RS04310	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BLTE_RS04320	COG1741	Belongs to the pirin family
BLTE_RS04355	COG1299	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLTE_RS04355	COG1445	protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity
BLTE_RS04360	COG1105	Belongs to the carbohydrate kinase PfkB family
BLTE_RS04365	COG4668	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLTE_RS04365	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BLTE_RS04380	COG2352	Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle
BLTE_RS04385	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BLTE_RS04400	COG1462	curli production assembly transport component CsgG
BLTE_RS04430	COG2307	Protein conserved in bacteria
BLTE_RS04430	COG2308	Evidence 4 Homologs of previously reported genes of
BLTE_RS04440	COG2252	PERMEase
BLTE_RS04535	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BLTE_RS04540	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BLTE_RS04545	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BLTE_RS04550	COG0649	NAD binding
BLTE_RS04560	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BLTE_RS04565	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BLTE_RS04575	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BLTE_RS04590	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BLTE_RS04600	COG0713	ATP synthesis coupled electron transport
BLTE_RS04615	COG1007	ATP synthesis coupled electron transport
BLTE_RS04630	COG0346	lactoylglutathione lyase activity
BLTE_RS04635	COG0442	prolyl-tRNA aminoacylation
BLTE_RS04645	COG1136	(ABC) transporter
BLTE_RS04655	COG0052	Belongs to the universal ribosomal protein uS2 family
BLTE_RS04660	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BLTE_RS04665	COG0528	UMP kinase activity
BLTE_RS04670	COG0233	cytoplasmic translational termination
BLTE_RS04675	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BLTE_RS04685	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BLTE_RS04690	COG0750	zinc metalloprotease
BLTE_RS04695	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BLTE_RS04700	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BLTE_RS04705	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLTE_RS04710	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BLTE_RS04715	COG3494	Protein of unknown function (DUF1009)
BLTE_RS04720	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BLTE_RS04745	COG2267	carboxylic ester hydrolase activity
BLTE_RS04775	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BLTE_RS04780	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BLTE_RS04785	COG2832	Protein of unknown function (DUF454)
BLTE_RS04790	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BLTE_RS04805	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BLTE_RS04810	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BLTE_RS04825	COG4166	transmembrane transport
BLTE_RS04840	COG2301	Belongs to the HpcH HpaI aldolase family
BLTE_RS04845	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BLTE_RS04850	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BLTE_RS04860	COG1183	phosphatidylcholine synthase activity
BLTE_RS04865	COG0861	Integral membrane protein TerC family
BLTE_RS04875	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLTE_RS04890	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BLTE_RS04930	COG0354	folic acid binding
BLTE_RS04940	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS04945	COG0259	pyridoxamine-phosphate oxidase activity
BLTE_RS04955	COG0484	heat shock protein binding
BLTE_RS04960	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BLTE_RS04980	COG1376	ErfK ybiS ycfS ynhG family protein
BLTE_RS05000	COG2197	response regulator
BLTE_RS05005	COG3916	Acyl-homoserine-lactone synthase
BLTE_RS05030	COG0746	molybdenum cofactor guanylyltransferase activity
BLTE_RS05040	COG1393	Belongs to the ArsC family
BLTE_RS05050	COG0640	Transcriptional regulator
BLTE_RS05070	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLTE_RS05075	COG4232	protein-disulfide reductase activity
BLTE_RS05085	COG1618	nucleotide phosphatase activity, acting on free nucleotides
BLTE_RS05085	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BLTE_RS05230	COG4397	Mu-like prophage major head subunit gpT
BLTE_RS05250	COG4383	Mu-like prophage protein gp29
BLTE_RS05355	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BLTE_RS05405	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BLTE_RS05450	COG0546	phosphoglycolate phosphatase activity
BLTE_RS05455	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BLTE_RS05490	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BLTE_RS05495	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BLTE_RS05510	COG1846	Transcriptional regulator
BLTE_RS05515	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BLTE_RS05520	COG3045	CreA protein
BLTE_RS05540	COG0215	cysteine-tRNA ligase activity
BLTE_RS05550	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BLTE_RS05560	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLTE_RS05570	COG1573	uracil-dna glycosylase
BLTE_RS05580	COG1758	RNA polymerase activity
BLTE_RS05590	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BLTE_RS05595	COG0736	holo-[acyl-carrier-protein] synthase activity
BLTE_RS05600	COG0681	Belongs to the peptidase S26 family
BLTE_RS05605	COG0571	ribonuclease III activity
BLTE_RS05610	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BLTE_RS05620	COG1381	Involved in DNA repair and RecF pathway recombination
BLTE_RS05635	COG3206	protein involved in exopolysaccharide biosynthesis
BLTE_RS05635	COG0489	protein tyrosine kinase activity
BLTE_RS05640	COG1278	Cold shock
BLTE_RS05765	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BLTE_RS05775	COG0583	DNA-binding transcription factor activity
BLTE_RS05780	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BLTE_RS05790	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLTE_RS05795	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BLTE_RS05820	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BLTE_RS05825	COG0629	single-stranded DNA binding
BLTE_RS05830	COG2202	Pas domain
BLTE_RS05830	COG3920	Histidine kinase
BLTE_RS05835	COG1473	amidohydrolase
BLTE_RS05845	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BLTE_RS05845	COG0493	'glutamate synthase
BLTE_RS05850	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BLTE_RS05850	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BLTE_RS05850	COG1013	pyruvate-flavodoxin oxidoreductase activity
BLTE_RS05850	COG0674	pyruvate-flavodoxin oxidoreductase activity
BLTE_RS05855	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS05860	COG3604	Transcriptional regulator
BLTE_RS05865	COG0535	radical SAM domain protein
BLTE_RS05870	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BLTE_RS05880	COG5554	nitrogen fixation
BLTE_RS05885	COG5554	nitrogen fixation
BLTE_RS05900	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BLTE_RS05905	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BLTE_RS05910	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BLTE_RS05915	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BLTE_RS05920	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BLTE_RS05925	COG1433	Dinitrogenase iron-molybdenum cofactor
BLTE_RS05935	COG3383	formate dehydrogenase (NAD+) activity
BLTE_RS05950	COG0316	Belongs to the HesB IscA family
BLTE_RS05975	COG2086	electron transfer activity
BLTE_RS05980	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BLTE_RS05985	COG0644	oxidoreductase
BLTE_RS05990	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BLTE_RS06000	COG1376	ErfK ybiS ycfS ynhG family protein
BLTE_RS06010	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BLTE_RS06025	COG0525	valine-tRNA ligase activity
BLTE_RS06030	COG2094	Belongs to the DNA glycosylase MPG family
BLTE_RS06040	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BLTE_RS06045	COG0708	Exodeoxyribonuclease III
BLTE_RS06050	COG0316	Belongs to the HesB IscA family
BLTE_RS06055	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BLTE_RS06060	COG0018	arginyl-trna synthetase
BLTE_RS06075	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BLTE_RS06080	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BLTE_RS06090	COG4372	Transposase
BLTE_RS06095	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS06100	COG2963	transposase activity
BLTE_RS06120	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS06175	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BLTE_RS06190	COG0484	heat shock protein binding
BLTE_RS06195	COG1686	Belongs to the peptidase S11 family
BLTE_RS06210	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BLTE_RS06280	COG2274	protein secretion by the type I secretion system
BLTE_RS06295	COG1236	Exonuclease of the beta-lactamase fold involved in RNA processing
BLTE_RS06305	COG2235	arginine
BLTE_RS06320	COG4372	Transposase
BLTE_RS06325	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS06330	COG2963	transposase activity
BLTE_RS06340	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLTE_RS06345	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BLTE_RS06375	COG1492	cobalamin metabolic process
BLTE_RS06395	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BLTE_RS06405	COG0784	Response regulator, receiver
BLTE_RS06450	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BLTE_RS06615	COG0717	Belongs to the dCTP deaminase family
BLTE_RS06625	COG3750	Belongs to the UPF0335 family
BLTE_RS06630	COG0629	single-stranded DNA binding
BLTE_RS06710	COG4570	Endonuclease that resolves Holliday junction intermediates made during homologous genetic recombination and DNA repair. Exhibits sequence and structure-selective cleavage of four-way DNA junctions, where it introduces symmetrical nicks in two strands of the same polarity at the 5' side of dinucleotides. Corrects the defects in genetic recombination and DNA repair associated with inactivation of ruvAB or ruvC
BLTE_RS06800	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BLTE_RS06815	COG1396	sequence-specific DNA binding
BLTE_RS06820	COG2188	Transcriptional regulator
BLTE_RS06855	COG0438	transferase activity, transferring glycosyl groups
BLTE_RS06860	COG1192	Involved in chromosome partitioning
BLTE_RS06865	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLTE_RS06870	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BLTE_RS06875	COG0805	protein transport
BLTE_RS06880	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BLTE_RS06885	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BLTE_RS06890	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BLTE_RS06915	COG1862	Preprotein translocase
BLTE_RS06920	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BLTE_RS06940	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BLTE_RS06945	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BLTE_RS06950	COG1530	ribonuclease E activity
BLTE_RS06950	COG1530	ribonuclease E activity
BLTE_RS06955	COG0860	N-Acetylmuramoyl-L-alanine amidase
BLTE_RS06975	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS06980	COG1129	ABC transporter
BLTE_RS06980	COG0842	Transport permease protein
BLTE_RS06985	COG0842	Transport permease protein
BLTE_RS07020	COG1121	(ABC) transporter
BLTE_RS07025	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLTE_RS07030	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BLTE_RS07035	COG0463	Glycosyl transferase, family 2
BLTE_RS07050	COG0626	cystathionine gamma-synthase activity
BLTE_RS07055	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLTE_RS07060	COG4597	amino acid ABC transporter
BLTE_RS07065	COG0765	amino acid transport
BLTE_RS07070	COG1126	abc transporter atp-binding protein
BLTE_RS07075	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BLTE_RS07080	COG2897	thiosulfate sulfurtransferase activity
BLTE_RS07090	COG0300	oxidoreductase activity
BLTE_RS07095	COG2211	Major facilitator Superfamily
BLTE_RS07100	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BLTE_RS07110	COG3349	Catalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'
BLTE_RS07115	COG0415	Belongs to the DNA photolyase family
BLTE_RS07120	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BLTE_RS07130	COG0840	transmembrane signaling receptor activity
BLTE_RS07145	COG2326	polyphosphate kinase activity
BLTE_RS07150	COG0739	heme binding
BLTE_RS07155	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BLTE_RS07165	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLTE_RS07170	COG0154	amidase activity
BLTE_RS07195	COG0326	Molecular chaperone. Has ATPase activity
BLTE_RS07200	COG0667	Aldo Keto reductase
BLTE_RS07210	COG3956	TIGRFAM MazG family protein
BLTE_RS07215	COG1235	May be involved in the transport of PQQ or its precursor to the periplasm
BLTE_RS07220	COG0084	hydrolase, TatD family'
BLTE_RS07230	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLTE_RS07235	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BLTE_RS07240	COG1686	Belongs to the peptidase S11 family
BLTE_RS07275	COG1392	Phosphate transport regulator
BLTE_RS07280	COG0306	phosphate transporter
BLTE_RS07295	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLTE_RS07300	COG3162	membrane
BLTE_RS07310	COG1053	succinate dehydrogenase
BLTE_RS07315	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLTE_RS07315	COG1648	precorrin-2 dehydrogenase activity
BLTE_RS07320	COG1797	cobyrinic acid a,c-diamide synthase activity
BLTE_RS07395	COG1053	succinate dehydrogenase
BLTE_RS07395	COG3976	FMN-binding domain protein
BLTE_RS07405	COG1013	pyruvate-flavodoxin oxidoreductase activity
BLTE_RS07410	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BLTE_RS07410	COG0674	pyruvate-flavodoxin oxidoreductase activity
BLTE_RS07420	COG2048	Heterodisulfide reductase, subunit B
BLTE_RS07465	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BLTE_RS07470	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BLTE_RS07475	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BLTE_RS07480	COG2205	protein histidine kinase activity
BLTE_RS07485	COG0745	RESPONSE REGULATOR receiver
BLTE_RS07490	COG2860	membrane
BLTE_RS07505	COG3119	arylsulfatase activity
BLTE_RS07625	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BLTE_RS07635	COG0540	Belongs to the ATCase OTCase family
BLTE_RS07640	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BLTE_RS07645	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BLTE_RS07650	COG0758	DNA mediated transformation
BLTE_RS07655	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BLTE_RS07655	COG1754	DNA topoisomerase type I activity
BLTE_RS07660	COG0557	exoribonuclease II activity
BLTE_RS07685	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLTE_RS07690	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BLTE_RS07700	COG1376	ErfK ybiS ycfS ynhG family protein
BLTE_RS07705	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BLTE_RS07710	COG0436	Aminotransferase
BLTE_RS07725	COG0511	ligase activity, forming carbon-carbon bonds
BLTE_RS07730	COG0439	Biotin carboxylase
BLTE_RS07750	COG0848	biopolymer transport protein
BLTE_RS07775	COG4771	TonB-dependent receptor
BLTE_RS07790	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BLTE_RS07795	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BLTE_RS07800	COG0589	response to stress
BLTE_RS07805	COG0659	secondary active sulfate transmembrane transporter activity
BLTE_RS07810	COG0625	glutathione transferase activity
BLTE_RS07820	COG3685	Protein conserved in bacteria
BLTE_RS07825	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BLTE_RS07835	COG2099	Precorrin-6x reductase
BLTE_RS07850	COG1233	COG1233 Phytoene dehydrogenase and related
BLTE_RS07940	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BLTE_RS07955	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BLTE_RS07980	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS07985	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BLTE_RS08005	COG2342	PFAM TM1410 hypothetical-related protein
BLTE_RS08030	COG4372	Transposase
BLTE_RS08035	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS08040	COG2963	transposase activity
BLTE_RS08060	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BLTE_RS08065	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLTE_RS08070	COG0438	transferase activity, transferring glycosyl groups
BLTE_RS08070	COG0297	glycogen (starch) synthase activity
BLTE_RS08080	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLTE_RS08090	COG0183	Belongs to the thiolase family
BLTE_RS08120	COG1960	acyl-CoA dehydrogenase activity
BLTE_RS08140	COG0183	Belongs to the thiolase family
BLTE_RS08145	COG0300	oxidoreductase activity
BLTE_RS08145	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS08145	COG3321	synthase
BLTE_RS08145	COG0318	PFAM AMP-dependent synthetase and ligase
BLTE_RS08145	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BLTE_RS08150	COG1024	Enoyl-CoA hydratase
BLTE_RS08160	COG1959	2 iron, 2 sulfur cluster binding
BLTE_RS08165	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS08215	COG1960	acyl-CoA dehydrogenase activity
BLTE_RS08230	COG0641	radical SAM
BLTE_RS08245	COG1132	(ABC) transporter
BLTE_RS08260	COG0583	DNA-binding transcription factor activity
BLTE_RS08265	COG0687	Required for the activity of the bacterial periplasmic transport system of putrescine
BLTE_RS08270	COG3842	ATPase activity
BLTE_RS08275	COG1176	ABC-type spermidine putrescine transport system, permease component I
BLTE_RS08280	COG1177	transmembrane transport
BLTE_RS08300	COG2181	nitrate reductase activity
BLTE_RS08300	COG0247	lactate metabolic process
BLTE_RS08320	COG1917	Cupin 2, conserved barrel domain protein
BLTE_RS08325	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BLTE_RS08355	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLTE_RS08365	COG1464	Belongs to the NlpA lipoprotein family
BLTE_RS08375	COG2011	ABC-type metal ion transport system permease component
BLTE_RS08395	COG1024	Enoyl-CoA hydratase
BLTE_RS08425	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLTE_RS08435	COG0625	glutathione transferase activity
BLTE_RS08450	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BLTE_RS08460	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BLTE_RS08465	COG1960	acyl-CoA dehydrogenase activity
BLTE_RS08470	COG5001	Diguanylate cyclase
BLTE_RS08470	COG3300	MHYT domain
BLTE_RS08475	COG2239	Acts as a magnesium transporter
BLTE_RS08480	COG0726	polysaccharide deacetylase
BLTE_RS08485	COG0726	polysaccharide deacetylase
BLTE_RS08500	COG0321	lipoyl(octanoyl) transferase activity
BLTE_RS08510	COG1254	Belongs to the acylphosphatase family
BLTE_RS08515	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BLTE_RS08520	COG4770	biotin carboxylase activity
BLTE_RS08540	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BLTE_RS08550	COG0546	phosphoglycolate phosphatase activity
BLTE_RS08560	COG0564	pseudouridine synthase activity
BLTE_RS08570	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLTE_RS08585	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BLTE_RS08590	COG3454	Phosphonate metabolism
BLTE_RS08595	COG4778	phosphonate C-P lyase system protein PhnL
BLTE_RS08600	COG4107	phosphonate C-P lyase system protein PhnK
BLTE_RS08605	COG3627	carbon phosphorus lyase activity
BLTE_RS08610	COG3626	phosphonate metabolism
BLTE_RS08615	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BLTE_RS08620	COG3624	Phosphonate C-P lyase system protein PhnG
BLTE_RS08625	COG2188	Transcriptional regulator
BLTE_RS08635	COG3639	organic phosphonate transmembrane transporter activity
BLTE_RS08640	COG3639	organic phosphonate transmembrane transporter activity
BLTE_RS08650	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BLTE_RS08660	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BLTE_RS08665	COG1324	tolerance protein
BLTE_RS08670	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BLTE_RS08695	COG2030	dehydratase
BLTE_RS08700	COG2301	Belongs to the HpcH HpaI aldolase family
BLTE_RS08715	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BLTE_RS08730	COG0203	ribosomal protein L17
BLTE_RS08735	COG0202	RNA polymerase activity
BLTE_RS08740	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BLTE_RS08745	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BLTE_RS08750	COG0563	adenylate kinase activity
BLTE_RS08755	COG0201	protein transport
BLTE_RS08760	COG0200	Binds to the 23S rRNA
BLTE_RS08765	COG1841	ribosomal large subunit assembly
BLTE_RS08770	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BLTE_RS08775	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BLTE_RS08780	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BLTE_RS08785	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BLTE_RS08790	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BLTE_RS08795	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BLTE_RS08800	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BLTE_RS08805	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BLTE_RS08810	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BLTE_RS08815	COG0255	Belongs to the universal ribosomal protein uL29 family
BLTE_RS08820	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BLTE_RS08825	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BLTE_RS08830	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BLTE_RS08835	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BLTE_RS08840	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BLTE_RS08845	COG0089	rRNA binding
BLTE_RS08850	COG0088	Forms part of the polypeptide exit tunnel
BLTE_RS08855	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BLTE_RS08860	COG0051	transcription antitermination factor activity, RNA binding
BLTE_RS08865	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BLTE_RS08870	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BLTE_RS08880	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BLTE_RS08890	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BLTE_RS08895	COG0085	RNA polymerase activity
BLTE_RS08905	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BLTE_RS08910	COG0081	regulation of translation
BLTE_RS08915	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BLTE_RS08925	COG0690	P-P-bond-hydrolysis-driven protein transmembrane transporter activity
BLTE_RS08935	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BLTE_RS08950	COG3585	molybdate ion transport
BLTE_RS08960	COG3842	ATPase activity
BLTE_RS08975	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BLTE_RS09000	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BLTE_RS09010	COG0302	gtp cyclohydrolase
BLTE_RS09015	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BLTE_RS09020	COG1752	Esterase of the alpha-beta hydrolase superfamily
BLTE_RS09040	COG0697	spore germination
BLTE_RS09070	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BLTE_RS09075	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLTE_RS09095	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLTE_RS09125	COG2831	hemolysin activation secretion protein
BLTE_RS09150	COG3166	PFAM Fimbrial assembly family protein
BLTE_RS09185	COG1459	type II secretion system
BLTE_RS09190	COG2804	Type II secretory pathway, ATPase PulE Tfp pilus assembly pathway, ATPase PilB
BLTE_RS09215	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BLTE_RS09220	COG1923	regulation of RNA biosynthetic process
BLTE_RS09230	COG2204	response regulator
BLTE_RS09235	COG5000	phosphorelay sensor kinase activity
BLTE_RS09245	COG2204	response regulator
BLTE_RS09255	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BLTE_RS09260	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BLTE_RS09260	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BLTE_RS09265	COG1546	Belongs to the CinA family
BLTE_RS09270	COG2867	negative regulation of translational initiation
BLTE_RS09275	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BLTE_RS09285	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLTE_RS09295	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLTE_RS09300	COG0022	dehydrogenase e1 component
BLTE_RS09300	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLTE_RS09305	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BLTE_RS09320	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BLTE_RS09325	COG2814	Major facilitator Superfamily
BLTE_RS09335	COG2022	thiamine diphosphate biosynthetic process
BLTE_RS09340	COG0352	thiamine-phosphate diphosphorylase activity
BLTE_RS09350	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BLTE_RS09355	COG0148	phosphopyruvate hydratase activity
BLTE_RS09365	COG0343	queuine tRNA-ribosyltransferase activity
BLTE_RS09370	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BLTE_RS09390	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BLTE_RS09400	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BLTE_RS09405	COG2226	methyltransferase
BLTE_RS09440	COG2989	Protein conserved in bacteria
BLTE_RS09450	COG1846	Transcriptional regulator
BLTE_RS09465	COG1024	Enoyl-CoA hydratase
BLTE_RS09480	COG1960	acyl-CoA dehydrogenase activity
BLTE_RS09485	COG0113	porphobilinogen synthase activity
BLTE_RS09495	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BLTE_RS09500	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS09530	COG0513	Belongs to the DEAD box helicase family
BLTE_RS09545	COG2337	Toxic component of a toxin-antitoxin (TA) module
BLTE_RS09550	COG0316	Belongs to the HesB IscA family
BLTE_RS09555	COG2151	metal-sulfur cluster biosynthetic enzyme
BLTE_RS09560	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BLTE_RS09565	COG0719	Fe-S assembly protein
BLTE_RS09570	COG0396	ATPase activity
BLTE_RS09580	COG0719	Fe-S assembly protein
BLTE_RS09590	COG2945	thiolester hydrolase activity
BLTE_RS09595	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BLTE_RS09600	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BLTE_RS09605	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BLTE_RS09610	COG1494	fructose-1,6-bisphosphatase
BLTE_RS09620	COG0436	Aminotransferase
BLTE_RS09630	COG3243	poly(R)-hydroxyalkanoic acid synthase
BLTE_RS09635	COG3905	.,Oxidizes proline to glutamate for use as a carbon and nitrogen source
BLTE_RS09640	COG4651	solute:proton antiporter activity
BLTE_RS09640	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BLTE_RS09645	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BLTE_RS09655	COG0183	Belongs to the thiolase family
BLTE_RS09660	COG0318	PFAM AMP-dependent synthetase and ligase
BLTE_RS09665	COG0010	Belongs to the arginase family
BLTE_RS09670	COG0187	DNA topoisomerase II activity
BLTE_RS09680	COG3668	Plasmid stabilization system
BLTE_RS09690	COG0248	Ppx GppA phosphatase
BLTE_RS09695	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BLTE_RS09705	COG0628	permease
BLTE_RS09715	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BLTE_RS09720	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BLTE_RS09730	COG1773	rubredoxin
BLTE_RS09745	COG0789	Transcriptional regulator
BLTE_RS09755	COG0861	Integral membrane protein TerC family
BLTE_RS09760	COG0105	UTP biosynthetic process
BLTE_RS09775	COG3260	NADH ubiquinone oxidoreductase 20
BLTE_RS09780	COG3262	NADH dehydrogenase (ubiquinone), 30 kDa subunit
BLTE_RS09780	COG3261	NADH dehydrogenase
BLTE_RS09785	COG0651	ATP synthesis coupled electron transport
BLTE_RS09795	COG0650	Formate hydrogenlyase subunit 4
BLTE_RS09800	COG0651	ATP synthesis coupled electron transport
BLTE_RS09805	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BLTE_RS09810	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLTE_RS09815	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BLTE_RS09820	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BLTE_RS09840	COG1560	Kdo2-lipid A biosynthetic process
BLTE_RS09850	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLTE_RS09850	COG1024	Enoyl-CoA hydratase
BLTE_RS09860	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BLTE_RS09925	COG1183	phosphatidylcholine synthase activity
BLTE_RS09935	COG5265	(ABC) transporter
BLTE_RS09940	COG0688	phosphatidylethanolamine metabolic process
BLTE_RS09955	COG3033	Beta-eliminating lyase
BLTE_RS09960	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BLTE_RS09965	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BLTE_RS09975	COG1024	Enoyl-CoA hydratase
BLTE_RS09980	COG1832	CoA-binding protein
BLTE_RS10010	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BLTE_RS10030	COG0628	permease
BLTE_RS10125	COG0270	DNA (cytosine-5-)-methyltransferase activity
BLTE_RS10310	COG2963	transposase activity
BLTE_RS10315	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS10320	COG4372	Transposase
BLTE_RS10340	COG0464	growth
BLTE_RS10345	COG1404	Belongs to the peptidase S8 family
BLTE_RS10355	COG1404	Belongs to the peptidase S8 family
BLTE_RS10360	COG0286	site-specific DNA-methyltransferase (adenine-specific) activity
BLTE_RS10375	COG3177	Filamentation induced by cAMP protein fic
BLTE_RS10435	COG0776	regulation of translation
BLTE_RS10440	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BLTE_RS10445	COG0416	fatty acid biosynthetic process
BLTE_RS10465	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BLTE_RS10470	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BLTE_RS10475	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLTE_RS10475	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BLTE_RS10485	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BLTE_RS10490	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLTE_RS10495	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BLTE_RS10500	COG2200	EAL domain
BLTE_RS10505	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BLTE_RS10510	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BLTE_RS10520	COG1850	ribulose-bisphosphate carboxylase activity
BLTE_RS10540	COG0175	sulfate reduction
BLTE_RS10550	COG0175	sulfate reduction
BLTE_RS10555	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BLTE_RS10565	COG1648	precorrin-2 dehydrogenase activity
BLTE_RS10565	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLTE_RS10570	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BLTE_RS10575	COG4208	sulfate ABC transporter
BLTE_RS10585	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BLTE_RS10590	COG1464	Belongs to the NlpA lipoprotein family
BLTE_RS10595	COG1464	Belongs to the NlpA lipoprotein family
BLTE_RS10600	COG2011	ABC-type metal ion transport system permease component
BLTE_RS10605	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BLTE_RS10625	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BLTE_RS10655	COG0535	radical SAM domain protein
BLTE_RS10675	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLTE_RS10680	COG4555	ABC transporter
BLTE_RS10700	COG3300	MHYT domain
BLTE_RS10700	COG5001	Diguanylate cyclase
BLTE_RS10705	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BLTE_RS10715	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BLTE_RS10720	COG0489	protein tyrosine kinase activity
BLTE_RS10735	COG2205	protein histidine kinase activity
BLTE_RS10735	COG2202	Pas domain
BLTE_RS10780	COG2226	methyltransferase
BLTE_RS10785	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BLTE_RS10810	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BLTE_RS10820	COG0168	Low-affinity potassium transport system. Interacts with trk system potassium uptake protein TrkA
BLTE_RS10850	COG1414	Transcriptional regulator
BLTE_RS10860	COG1230	cation diffusion facilitator family transporter
BLTE_RS10870	COG0308	aminopeptidase N
BLTE_RS10875	COG2202	Pas domain
BLTE_RS10875	COG2205	protein histidine kinase activity
BLTE_RS10880	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BLTE_RS10885	COG2205	protein histidine kinase activity
BLTE_RS11060	COG4235	cytochrome complex assembly
BLTE_RS11065	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BLTE_RS11070	COG1138	Cytochrome C-type biogenesis protein
BLTE_RS11075	COG3088	subunit of a heme lyase
BLTE_RS11095	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BLTE_RS11115	COG0483	inositol monophosphate 1-phosphatase activity
BLTE_RS11120	COG2267	carboxylic ester hydrolase activity
BLTE_RS11125	COG0071	Belongs to the small heat shock protein (HSP20) family
BLTE_RS11135	COG0070	glutamate synthase
BLTE_RS11135	COG0067	glutamate synthase
BLTE_RS11135	COG0069	glutamate synthase activity
BLTE_RS11150	COG2951	lytic endotransglycosylase activity
BLTE_RS11155	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BLTE_RS11160	COG0330	HflC and HflK could
BLTE_RS11190	COG2226	methyltransferase
BLTE_RS11195	COG0482	sulfurtransferase activity
BLTE_RS11210	COG1766	The M ring may be actively involved in energy transduction
BLTE_RS11215	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLTE_RS11225	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BLTE_RS11230	COG2204	response regulator
BLTE_RS11250	COG0163	prenyltransferase activity
BLTE_RS11255	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BLTE_RS11260	COG4953	penicillin-binding protein 1C
BLTE_RS11265	COG2373	Large extracellular alpha-helical protein
BLTE_RS11270	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BLTE_RS11275	COG0579	oxidoreductase
BLTE_RS11280	COG1733	regulation of RNA biosynthetic process
BLTE_RS11285	COG0431	NADPH-dependent FMN reductase
BLTE_RS11290	COG0840	transmembrane signaling receptor activity
BLTE_RS11295	COG4214	carbohydrate transport
BLTE_RS11300	COG0559	Belongs to the binding-protein-dependent transport system permease family
BLTE_RS11325	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BLTE_RS11380	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS11390	COG0504	CTP synthase activity
BLTE_RS11400	COG0149	triose-phosphate isomerase activity
BLTE_RS11405	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BLTE_RS11410	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BLTE_RS11420	COG0737	Belongs to the 5'-nucleotidase family
BLTE_RS11430	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BLTE_RS11435	COG0134	indole-3-glycerol-phosphate synthase activity
BLTE_RS11440	COG0315	cyclic pyranopterin monophosphate synthase activity
BLTE_RS11445	COG0303	'Molybdopterin
BLTE_RS11475	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BLTE_RS11480	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BLTE_RS11485	COG0740	serine-type endopeptidase activity
BLTE_RS11490	COG0544	peptidyl-prolyl cis-trans isomerase activity
BLTE_RS11510	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BLTE_RS11510	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BLTE_RS11515	COG0347	Belongs to the P(II) protein family
BLTE_RS11520	COG0174	glutamine synthetase
BLTE_RS11525	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BLTE_RS11530	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BLTE_RS11545	COG3203	Forms passive diffusion pores that allow small molecular weight hydrophilic materials across the outer membrane
BLTE_RS11575	COG0523	cobalamin synthesis protein
BLTE_RS11590	COG1121	(ABC) transporter
BLTE_RS11595	COG2217	Heavy metal translocating P-type atpase
BLTE_RS11605	COG0778	Nitroreductase
BLTE_RS11615	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BLTE_RS11645	COG0312	modulator of DNA gyrase
BLTE_RS11650	COG0483	inositol monophosphate 1-phosphatase activity
BLTE_RS11660	COG1519	Transferase
BLTE_RS11665	COG1663	tetraacyldisaccharide 4'-kinase activity
BLTE_RS11675	COG1570	exodeoxyribonuclease VII activity
BLTE_RS11690	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BLTE_RS11700	COG0424	maF-like protein
BLTE_RS11715	COG5328	Belongs to the UPF0262 family
BLTE_RS11730	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BLTE_RS11735	COG0129	dihydroxy-acid dehydratase activity
BLTE_RS11745	COG2202	Pas domain
BLTE_RS11745	COG3920	Histidine kinase
BLTE_RS11755	COG0521	Mo-molybdopterin cofactor biosynthetic process
BLTE_RS11775	COG0247	lactate metabolic process
BLTE_RS11780	COG1139	Iron-sulfur cluster binding protein
BLTE_RS11785	COG1556	Lactate utilization protein
BLTE_RS11805	COG2989	Protein conserved in bacteria
BLTE_RS11810	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BLTE_RS11815	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BLTE_RS11835	COG0559	Belongs to the binding-protein-dependent transport system permease family
BLTE_RS11845	COG1022	Amp-dependent synthetase and ligase
BLTE_RS11855	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BLTE_RS11880	COG0071	Belongs to the small heat shock protein (HSP20) family
BLTE_RS11910	COG3038	cytochrome b561
BLTE_RS11940	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLTE_RS11985	COG1584	GPR1 FUN34 yaaH family protein
BLTE_RS12020	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BLTE_RS12040	COG1393	Belongs to the ArsC family
BLTE_RS12070	COG0123	including yeast histone deacetylase and acetoin utilization protein
BLTE_RS12085	COG0004	ammonium transporteR
BLTE_RS12090	COG1722	exodeoxyribonuclease VII activity
BLTE_RS12095	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BLTE_RS12105	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BLTE_RS12110	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BLTE_RS12130	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLTE_RS12130	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BLTE_RS12135	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BLTE_RS12150	COG0277	FAD linked oxidase domain protein
BLTE_RS12160	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BLTE_RS12175	COG0368	Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate
BLTE_RS12180	COG0406	alpha-ribazole phosphatase activity
BLTE_RS12185	COG1492	cobalamin metabolic process
BLTE_RS12195	COG1703	isobutyryl-CoA mutase activity
BLTE_RS12205	COG0574	Belongs to the PEP-utilizing enzyme family
BLTE_RS12205	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BLTE_RS12215	COG1335	isochorismatase
BLTE_RS12220	COG0752	glycyl-tRNA synthetase alpha subunit
BLTE_RS12225	COG2835	tetraacyldisaccharide 4'-kinase activity
BLTE_RS12235	COG3118	belongs to the thioredoxin family
BLTE_RS12255	COG1088	dTDP-glucose 4,6-dehydratase activity
BLTE_RS12260	COG0438	transferase activity, transferring glycosyl groups
BLTE_RS12260	COG1216	Glycosyl transferase, family 2
BLTE_RS12295	COG1032	radical SAM domain protein
BLTE_RS12305	COG0180	Tryptophanyl-tRNA synthetase
BLTE_RS12315	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BLTE_RS12340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLTE_RS12345	COG1702	phosphate starvation-inducible protein PhoH
BLTE_RS12360	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BLTE_RS12365	COG1396	sequence-specific DNA binding
BLTE_RS12370	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BLTE_RS12375	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BLTE_RS12395	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BLTE_RS12400	COG1053	succinate dehydrogenase
BLTE_RS12405	COG1215	transferase activity, transferring glycosyl groups
BLTE_RS12410	COG1752	Esterase of the alpha-beta hydrolase superfamily
BLTE_RS12415	COG0757	Catalyzes a trans-dehydration via an enolate intermediate
BLTE_RS12425	COG0475	glutathione-regulated potassium exporter activity
BLTE_RS12425	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BLTE_RS12445	COG0583	DNA-binding transcription factor activity
BLTE_RS12450	COG0456	acetyltransferase
BLTE_RS12455	COG0174	glutamine synthetase
BLTE_RS12460	COG3842	ATPase activity
BLTE_RS12465	COG1176	ABC-type spermidine putrescine transport system, permease component I
BLTE_RS12470	COG1177	transmembrane transport
BLTE_RS12475	COG0166	Belongs to the GPI family
BLTE_RS12485	COG3093	addiction module antidote protein HigA
BLTE_RS12490	COG0312	modulator of DNA gyrase
BLTE_RS12505	COG0612	Peptidase, M16
BLTE_RS12510	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BLTE_RS12515	COG1742	UPF0060 membrane protein
BLTE_RS12530	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BLTE_RS12540	COG2610	gluconate transmembrane transporter activity
BLTE_RS12560	COG0637	HAD-superfamily hydrolase subfamily IA, variant 3
BLTE_RS12595	COG2963	transposase activity
BLTE_RS12600	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS12620	COG4372	Transposase
BLTE_RS12625	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS12630	COG2963	transposase activity
BLTE_RS12640	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BLTE_RS12645	COG1089	Catalyzes the conversion of GDP-D-mannose to GDP-4- dehydro-6-deoxy-D-mannose
BLTE_RS12680	COG0110	maltose O-acetyltransferase activity
BLTE_RS12685	COG0297	glycogen (starch) synthase activity
BLTE_RS12715	COG2148	undecaprenyl-phosphate glucose phosphotransferase activity
BLTE_RS12725	COG0628	permease
BLTE_RS12730	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BLTE_RS12735	COG0282	Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction
BLTE_RS12810	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BLTE_RS12845	COG3300	MHYT domain
BLTE_RS12845	COG5001	Diguanylate cyclase
BLTE_RS12850	COG0436	Aminotransferase
BLTE_RS12860	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BLTE_RS12870	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BLTE_RS12875	COG0583	DNA-binding transcription factor activity
BLTE_RS12880	COG0492	ferredoxin-NADP+ reductase activity
BLTE_RS12890	COG1522	sequence-specific DNA binding
BLTE_RS12900	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BLTE_RS12905	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BLTE_RS12915	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BLTE_RS12920	COG0305	Participates in initiation and elongation during chromosome replication
BLTE_RS12925	COG0628	permease
BLTE_RS12940	COG1320	monovalent cation:proton antiporter activity
BLTE_RS12950	COG1006	Multisubunit Na H antiporter MnhC subunit
BLTE_RS12955	COG1007	ATP synthesis coupled electron transport
BLTE_RS12980	COG3064	Membrane
BLTE_RS12995	COG1280	lysine exporter protein (LysE YggA)
BLTE_RS13005	COG0778	Nitroreductase
BLTE_RS13015	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BLTE_RS13020	COG1468	defense response to virus
BLTE_RS13020	COG1518	maintenance of DNA repeat elements
BLTE_RS13080	COG2885	chlorophyll binding
BLTE_RS13090	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BLTE_RS13110	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BLTE_RS13115	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BLTE_RS13120	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BLTE_RS13135	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BLTE_RS13145	COG0360	Binds together with S18 to 16S ribosomal RNA
BLTE_RS13150	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BLTE_RS13160	COG0359	binds to the 23S rRNA
BLTE_RS13175	COG5001	Diguanylate cyclase
BLTE_RS13175	COG3300	MHYT domain
BLTE_RS13195	COG0488	(ABC) transporter
BLTE_RS13220	COG1376	ErfK ybiS ycfS ynhG family protein
BLTE_RS13225	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BLTE_RS13225	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BLTE_RS13240	COG0519	Catalyzes the synthesis of GMP from XMP
BLTE_RS13240	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BLTE_RS13260	COG0420	3'-5' exonuclease activity
BLTE_RS13275	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BLTE_RS13280	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BLTE_RS13315	COG0375	protein maturation
BLTE_RS13345	COG2204	response regulator
BLTE_RS13375	COG0864	Transcriptional regulator
BLTE_RS13380	COG1960	acyl-CoA dehydrogenase activity
BLTE_RS13385	COG0183	Belongs to the thiolase family
BLTE_RS13395	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLTE_RS13400	COG2207	Transcriptional regulator
BLTE_RS13405	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BLTE_RS13415	COG4208	sulfate ABC transporter
BLTE_RS13420	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BLTE_RS13435	COG0716	FMN binding
BLTE_RS13460	COG1342	Belongs to the UPF0251 family
BLTE_RS13485	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BLTE_RS13510	COG1136	(ABC) transporter
BLTE_RS13515	COG0577	efflux transmembrane transporter activity
BLTE_RS13515	COG1136	(ABC) transporter
BLTE_RS13550	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BLTE_RS13570	COG0438	transferase activity, transferring glycosyl groups
BLTE_RS13580	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BLTE_RS13585	COG0596	Alpha beta hydrolase
BLTE_RS13620	COG2824	Alkylphosphonate utilization operon protein PhnA
BLTE_RS13665	COG3617	BRO family, N-terminal domain
BLTE_RS13715	COG2205	protein histidine kinase activity
BLTE_RS13725	COG2166	iron-sulfur cluster assembly
BLTE_RS13760	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BLTE_RS13820	COG4957	zinc ion binding
BLTE_RS13825	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLTE_RS13840	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BLTE_RS13850	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BLTE_RS13860	COG5002	protein histidine kinase activity
BLTE_RS13860	COG2176	DNA-directed DNA polymerase activity
BLTE_RS13865	COG2176	DNA-directed DNA polymerase activity
BLTE_RS13870	COG1275	C4-dicarboxylate transporter malic acid transport protein
BLTE_RS13875	COG0640	Transcriptional regulator
BLTE_RS13880	COG0697	spore germination
BLTE_RS13885	COG2814	Major facilitator Superfamily
BLTE_RS13900	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BLTE_RS13910	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BLTE_RS13915	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BLTE_RS13920	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BLTE_RS13930	COG0072	phenylalanine-tRNA ligase activity
BLTE_RS13930	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BLTE_RS13945	COG1132	(ABC) transporter
BLTE_RS13965	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BLTE_RS13970	COG2171	N-acyltransferase activity
BLTE_RS13980	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BLTE_RS13990	COG2771	luxR family
BLTE_RS14025	COG1137	ATPase activity
BLTE_RS14030	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BLTE_RS14035	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BLTE_RS14040	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLTE_RS14080	COG2010	Cytochrome c
BLTE_RS14095	COG3278	Belongs to the heme-copper respiratory oxidase family
BLTE_RS14100	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLTE_RS14105	COG1999	signal sequence binding
BLTE_RS14160	COG0488	(ABC) transporter
BLTE_RS14165	COG1671	Belongs to the UPF0178 family
BLTE_RS14170	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BLTE_RS14190	COG1160	GTP binding
BLTE_RS14195	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BLTE_RS14205	COG0826	peptidase U32
BLTE_RS14210	COG0826	peptidase U32
BLTE_RS14220	COG1598	PFAM Uncharacterised protein family UPF0150
BLTE_RS14240	COG1404	Belongs to the peptidase S8 family
BLTE_RS14245	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BLTE_RS14255	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BLTE_RS14260	COG1703	isobutyryl-CoA mutase activity
BLTE_RS14270	COG0673	inositol 2-dehydrogenase activity
BLTE_RS14280	COG0728	peptidoglycan biosynthetic process
BLTE_RS14285	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS14315	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BLTE_RS14320	COG1181	Belongs to the D-alanine--D-alanine ligase family
BLTE_RS14330	COG2267	carboxylic ester hydrolase activity
BLTE_RS14335	COG0770	UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity
BLTE_RS14340	COG0725	ABC transporter, periplasmic molybdate-binding protein
BLTE_RS14345	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BLTE_RS14350	COG3422	double-strand break repair
BLTE_RS14390	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLTE_RS14440	COG0101	tRNA pseudouridine synthase activity
BLTE_RS14445	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BLTE_RS14450	COG0728	peptidoglycan biosynthetic process
BLTE_RS14455	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLTE_RS14460	COG0443	Heat shock 70 kDa protein
BLTE_RS14465	COG0484	heat shock protein binding
BLTE_RS14470	COG3963	phosphatidate phosphatase activity
BLTE_RS14475	COG0284	orotidine-5'-phosphate decarboxylase activity
BLTE_RS14485	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BLTE_RS14490	COG0588	phosphoglycerate mutase activity
BLTE_RS14500	COG0177	DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'-phosphate
BLTE_RS14505	COG1238	metal cluster binding
BLTE_RS14520	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BLTE_RS14530	COG4691	Plasmid stability protein
BLTE_RS14535	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BLTE_RS14540	COG2226	methyltransferase
BLTE_RS14545	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BLTE_RS14585	COG0433	COG0433 Predicted ATPase
BLTE_RS14600	COG5001	Diguanylate cyclase
BLTE_RS14600	COG3300	MHYT domain
BLTE_RS14605	COG1012	belongs to the aldehyde dehydrogenase family
BLTE_RS14615	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BLTE_RS14620	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BLTE_RS14630	COG0745	RESPONSE REGULATOR receiver
BLTE_RS14635	COG0704	Plays a role in the regulation of phosphate uptake
BLTE_RS14640	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BLTE_RS14650	COG0573	inorganic phosphate transmembrane transporter activity
BLTE_RS14660	COG5002	protein histidine kinase activity
BLTE_RS14675	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BLTE_RS14695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLTE_RS14695	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BLTE_RS14705	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BLTE_RS14710	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BLTE_RS14715	COG1185	polyribonucleotide nucleotidyltransferase activity
BLTE_RS14725	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BLTE_RS14730	COG2862	Uncharacterized protein family, UPF0114
BLTE_RS14755	COG0706	membrane insertase activity
BLTE_RS14760	COG0594	ribonuclease P activity
BLTE_RS14765	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BLTE_RS14775	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BLTE_RS14780	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BLTE_RS14785	COG0539	negative regulation of cytoplasmic translation
BLTE_RS14790	COG0616	signal peptide processing
BLTE_RS14795	COG0776	regulation of translation
BLTE_RS14815	COG0135	phosphoribosylanthranilate isomerase activity
BLTE_RS14820	COG0133	tryptophan synthase activity
BLTE_RS14825	COG0159	tryptophan synthase activity
BLTE_RS14830	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BLTE_RS14850	COG1286	toxin biosynthetic process
BLTE_RS14855	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BLTE_RS14860	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS14865	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BLTE_RS14870	COG0418	dihydroorotase activity
BLTE_RS14885	COG1086	Polysaccharide biosynthesis protein
BLTE_RS14895	COG0285	dihydrofolate synthase activity
BLTE_RS14900	COG3920	Histidine kinase
BLTE_RS14950	COG0358	DNA primase activity
BLTE_RS14955	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLTE_RS15030	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BLTE_RS15085	COG1674	ftsk spoiiie
BLTE_RS15100	COG4372	Transposase
BLTE_RS15105	COG3436	PFAM IS66 Orf2 family protein
BLTE_RS15110	COG2963	transposase activity
BLTE_RS15140	COG0378	Facilitates the functional incorporation of the urease nickel metallocenter. This process requires GTP hydrolysis, probably effectuated by UreG
BLTE_RS15145	COG0830	nickel cation binding
BLTE_RS15155	COG0804	urea catabolic process
BLTE_RS15160	COG0832	Belongs to the urease beta subunit family
BLTE_RS15165	COG0831	urea catabolic process
BLTE_RS15170	COG0829	nickel cation binding
BLTE_RS15225	COG0640	Transcriptional regulator
BLTE_RS15235	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BLTE_RS15235	COG1648	precorrin-2 dehydrogenase activity
BLTE_RS15245	COG1797	cobyrinic acid a,c-diamide synthase activity
BLTE_RS15290	COG2923	Belongs to the DsrF TusC family
BLTE_RS15295	COG1553	Part of a sulfur-relay system required for 2-thiolation of 5-methylaminomethyl-2-thiouridine (mnm(5)s(2)U) at tRNA wobble positions. Accepts sulfur from TusA and transfers it in turn to TusE
BLTE_RS15300	COG2221	Nitrite and sulphite reductase 4Fe-4S
BLTE_RS15305	COG2221	Nitrite and sulphite reductase 4Fe-4S
BLTE_RS15320	COG0446	pyridine nucleotide-disulphide oxidoreductase
BLTE_RS15325	COG2855	membrane
BLTE_RS15330	COG2210	Belongs to the sulfur carrier protein TusA family
BLTE_RS15335	COG0425	Belongs to the sulfur carrier protein TusA family
BLTE_RS15340	COG0640	Transcriptional regulator
BLTE_RS15350	COG2030	dehydratase
BLTE_RS15370	COG1053	succinate dehydrogenase
BLTE_RS15385	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BLTE_RS15390	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BLTE_RS15400	COG0508	dehydrogenase complex catalyzes the overall conversion of
BLTE_RS15420	COG0045	succinate-CoA ligase (ADP-forming) activity
BLTE_RS15435	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BLTE_RS15470	COG2606	Belongs to the prolyl-tRNA editing family. YbaK EbsC subfamily
BLTE_RS15480	COG0505	Belongs to the CarA family
BLTE_RS15500	COG0745	RESPONSE REGULATOR receiver
BLTE_RS15505	COG2205	protein histidine kinase activity
BLTE_RS15515	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BLTE_RS15515	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLTE_RS15520	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BLTE_RS15525	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BLTE_RS15530	COG0556	nucleotide-excision repair
BLTE_RS15535	COG2321	neutral zinc metallopeptidase
BLTE_RS15555	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BLTE_RS15565	COG1573	uracil-dna glycosylase
BLTE_RS15580	COG0596	Alpha beta hydrolase
BLTE_RS15585	COG0142	geranyltranstransferase activity
BLTE_RS15595	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BLTE_RS15600	COG4149	molybdate abc transporter
BLTE_RS15605	COG0725	ABC transporter, periplasmic molybdate-binding protein
BLTE_RS15630	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BLTE_RS15640	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BLTE_RS15645	COG0251	oxidation-reduction process
BLTE_RS15650	COG1509	lysine 2,3-aminomutase activity
BLTE_RS15655	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BLTE_RS15660	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BLTE_RS15665	COG0140	phosphoribosyl-ATP diphosphatase activity
BLTE_RS15670	COG1132	(ABC) transporter
BLTE_RS15680	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLTE_RS15680	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BLTE_RS15690	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BLTE_RS15735	COG1961	COG1961 Site-specific recombinases, DNA invertase Pin homologs
BLTE_RS15745	COG0784	Response regulator, receiver
BLTE_RS15745	COG5002	protein histidine kinase activity
BLTE_RS15745	COG2205	protein histidine kinase activity
BLTE_RS15765	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BLTE_RS15770	COG0280	phosphate acetyltransferase
BLTE_RS15770	COG0281	malic enzyme
BLTE_RS15775	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BLTE_RS15780	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BLTE_RS15795	COG2205	protein histidine kinase activity
BLTE_RS15800	COG3178	'Phosphotransferase
BLTE_RS15805	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BLTE_RS15825	COG1074	ATP-dependent DNA helicase activity
BLTE_RS15840	COG1487	ribonuclease activity
BLTE_RS15870	COG0179	Fumarylacetoacetate (FAA) hydrolase
BLTE_RS15880	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BLTE_RS15885	COG1309	transcriptional regulator
BLTE_RS15890	COG1396	sequence-specific DNA binding
BLTE_RS15895	COG0351	phosphomethylpyrimidine kinase
BLTE_RS15900	COG0352	thiamine-phosphate diphosphorylase activity
BLTE_RS15905	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BLTE_RS15915	COG0339	signal peptide processing
BLTE_RS15930	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLTE_RS15945	COG0189	ligase activity
BLTE_RS15950	COG0792	nuclease activity
BLTE_RS15955	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BLTE_RS15965	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BLTE_RS15970	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BLTE_RS15975	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BLTE_RS15980	COG1420	regulation of RNA biosynthetic process
BLTE_RS15985	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BLTE_RS15990	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BLTE_RS16010	COG0052	Belongs to the universal ribosomal protein uS2 family
BLTE_RS16025	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BLTE_RS16035	COG1072	(Pantothenic acid kinase))
BLTE_RS16040	COG0140	phosphoribosyl-ATP diphosphatase activity
BLTE_RS16045	COG0107	imidazoleglycerol-phosphate synthase activity
BLTE_RS16050	COG0106	1-(5-phosphoribosyl)-5- 5-phosphoribosylamino)methylideneamino imidazole-4-carboxamide isomerase
BLTE_RS16055	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BLTE_RS16065	COG0131	Imidazoleglycerol-phosphate dehydratase
BLTE_RS16070	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BLTE_RS16075	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BLTE_RS16080	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BLTE_RS16090	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BLTE_RS16100	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BLTE_RS16105	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BLTE_RS16110	COG0237	dephospho-CoA kinase activity
BLTE_RS16115	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BLTE_RS16120	COG0424	maF-like protein
BLTE_RS16125	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BLTE_RS16130	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BLTE_RS16135	COG1981	membrane
BLTE_RS16140	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BLTE_RS16145	COG1331	Highly conserved protein containing a thioredoxin domain
BLTE_RS16150	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BLTE_RS16155	COG0445	tRNA wobble uridine modification
BLTE_RS16160	COG0357	Ribosomal RNA small subunit methyltransferase G
BLTE_RS16185	COG0495	leucyl-tRNA aminoacylation
BLTE_RS16205	COG1595	DNA-templated transcription, initiation
BLTE_RS16215	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BLTE_RS16220	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BLTE_RS16225	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BLTE_RS16230	COG1764	response to oxidative stress
BLTE_RS16235	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BLTE_RS16240	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BLTE_RS16250	COG0494	nUDIX hydrolase
BLTE_RS16260	COG0793	Belongs to the peptidase S41A family
BLTE_RS16270	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BLTE_RS16275	COG0799	negative regulation of ribosome biogenesis
BLTE_RS16280	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BLTE_RS16300	COG2723	6-phospho-beta-galactosidase activity
BLTE_RS16310	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BLTE_RS16315	COG1993	acr, cog1993
BLTE_RS16335	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BLTE_RS16340	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BLTE_RS16345	COG3750	Belongs to the UPF0335 family
BLTE_RS16350	COG1704	LemA family
BLTE_RS16355	COG0501	Belongs to the peptidase M48B family
BLTE_RS16365	COG1611	Belongs to the LOG family
BLTE_RS16380	COG0678	peroxiredoxin activity
BLTE_RS16380	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BLTE_RS16390	COG1678	Uncharacterized ACR, COG1678
BLTE_RS16400	COG1028	Short-chain dehydrogenase reductase Sdr
BLTE_RS16400	COG3321	synthase
BLTE_RS16400	COG0604	alcohol dehydrogenase
BLTE_RS16415	COG0254	rRNA binding
BLTE_RS16420	COG1132	(ABC) transporter
BLTE_RS16445	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLTE_RS16450	COG1376	ErfK ybiS ycfS ynhG family protein
BLTE_RS16450	COG1388	LysM domain
BLTE_RS16455	COG2917	probably involved in intracellular septation
BLTE_RS16460	COG0552	protein localization to endoplasmic reticulum
BLTE_RS16465	COG0564	pseudouridine synthase activity
BLTE_RS16475	COG2989	Protein conserved in bacteria
BLTE_RS16500	COG3243	poly(R)-hydroxyalkanoic acid synthase
BLTE_RS16505	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BLTE_RS16510	COG0784	Response regulator, receiver
BLTE_RS16515	COG0058	SHG alpha-glucan phosphorylase activity
BLTE_RS16520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BLTE_RS16525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BLTE_RS16530	COG0297	glycogen (starch) synthase activity
BLTE_RS16535	COG1523	belongs to the glycosyl hydrolase 13 family
BLTE_RS16545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BLTE_RS16550	COG1946	Acyl-CoA thioesterase
BLTE_RS16555	COG0347	Belongs to the P(II) protein family
BLTE_RS16560	COG0004	ammonium transporteR
BLTE_RS16570	COG1674	ftsk spoiiie
BLTE_RS16575	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BLTE_RS16590	COG0066	3-isopropylmalate dehydratase activity
BLTE_RS16605	COG2154	pterin-4-alpha-carbinolamine dehydratase
BLTE_RS16610	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BLTE_RS16620	COG4181	ATPase activity
BLTE_RS16635	COG0670	Belongs to the BI1 family
BLTE_RS16655	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BLTE_RS16660	COG4133	protoheme IX ABC transporter activity
BLTE_RS16665	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLTE_RS16670	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BLTE_RS16680	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BLTE_RS16710	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BLTE_RS16725	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BLTE_RS16740	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BLTE_RS16760	COG0784	Response regulator, receiver
BLTE_RS16780	COG0181	hydroxymethylbilane synthase activity
BLTE_RS16785	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BLTE_RS16790	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BLTE_RS16795	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BLTE_RS16820	COG1329	Transcriptional regulator
BLTE_RS16825	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BLTE_RS16865	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BLTE_RS16880	COG3339	Conserved Protein
BLTE_RS16900	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BLTE_RS16905	COG0288	reversible hydration of carbon dioxide
BLTE_RS16920	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BLTE_RS16935	COG0473	3-isopropylmalate dehydrogenase activity
BLTE_RS16940	COG2951	lytic endotransglycosylase activity
BLTE_RS16960	COG0671	phosphoesterase, PA-phosphatase related
BLTE_RS16965	COG0137	argininosuccinate synthase activity
BLTE_RS16975	COG0501	Belongs to the peptidase M48B family
BLTE_RS16990	COG0138	bifunctional purine biosynthesis protein purh
BLTE_RS17000	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BLTE_RS17005	COG1247	-acetyltransferase
BLTE_RS17010	COG1994	Peptidase M50
BLTE_RS17010	COG0517	IMP dehydrogenase activity
BLTE_RS17015	COG1994	Peptidase M50
BLTE_RS17015	COG0517	IMP dehydrogenase activity
BLTE_RS17020	COG1217	gtp-binding protein TYPA
BLTE_RS17025	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BLTE_RS17025	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BLTE_RS17035	COG0604	alcohol dehydrogenase
BLTE_RS17045	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BLTE_RS17050	COG0183	Belongs to the thiolase family
BLTE_RS17060	COG0697	spore germination
BLTE_RS17070	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BLTE_RS17090	COG0287	Prephenate dehydrogenase
BLTE_RS17095	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BLTE_RS17105	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BLTE_RS17110	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BLTE_RS17110	COG2813	Specifically methylates the guanine in position
BLTE_RS17115	COG0668	transmembrane transport
BLTE_RS17145	COG2884	Cell division ATP-binding protein ftsE
BLTE_RS17155	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BLTE_RS17180	COG0019	diaminopimelate decarboxylase activity
BLTE_RS17190	COG0165	Argininosuccinate lyase
BLTE_RS17195	COG1250	3-hydroxyacyl-CoA dehydrogenase
BLTE_RS17200	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BLTE_RS17205	COG2086	electron transfer activity
BLTE_RS17240	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BLTE_RS17255	COG3158	transport of potassium into the cell
BLTE_RS17260	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BLTE_RS17265	COG0735	belongs to the Fur family
BLTE_RS17270	COG0443	Heat shock 70 kDa protein
BLTE_RS17275	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BLTE_RS17285	COG0335	large ribosomal subunit rRNA binding
BLTE_RS17290	COG0336	Belongs to the RNA methyltransferase TrmD family
BLTE_RS17295	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BLTE_RS17300	COG0228	four-way junction DNA binding
BLTE_RS17305	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BLTE_RS17315	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BLTE_RS17325	COG0483	inositol monophosphate 1-phosphatase activity
BLTE_RS17340	COG0126	phosphoglycerate kinase activity
BLTE_RS17375	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BLTE_RS17380	COG1692	metallophosphoesterase
BLTE_RS17385	COG3932	Exopolysaccharide synthesis, ExoD
BLTE_RS17395	COG0217	transcriptional regulatory protein
BLTE_RS17405	COG0765	amino acid transport
BLTE_RS17410	COG0765	amino acid transport
BLTE_RS17415	COG1126	abc transporter atp-binding protein
BLTE_RS17420	COG3264	Mechanosensitive ion channel
BLTE_RS17420	COG1196	nuclear chromosome segregation
BLTE_RS17430	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLTE_RS17445	COG0523	cobalamin synthesis protein
BLTE_RS17450	COG1686	Belongs to the peptidase S11 family
BLTE_RS17460	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BLTE_RS17465	COG1643	Atp-dependent helicase
BLTE_RS17490	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLTE_RS17535	COG4964	Belongs to the GSP D family
BLTE_RS17570	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BLTE_RS17580	COG0791	NLP P60 protein
BLTE_RS17600	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BLTE_RS17605	COG4166	transmembrane transport
BLTE_RS17610	COG4166	transmembrane transport
BLTE_RS17615	COG4174	ABC transporter (Permease)
BLTE_RS17620	COG4239	(ABC) transporter, permease
BLTE_RS17635	COG4172	Belongs to the ABC transporter superfamily
BLTE_RS17655	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BLTE_RS17660	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BLTE_RS17665	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BLTE_RS17670	COG2223	nitrite transmembrane transporter activity
BLTE_RS17675	COG0242	peptide deformylase activity
BLTE_RS17680	COG0789	Transcriptional regulator
BLTE_RS17690	COG0730	response to heat
BLTE_RS17700	COG2226	methyltransferase
BLTE_RS17710	COG0167	dihydroorotate dehydrogenase activity
BLTE_RS17730	COG0657	acetylesterase activity
BLTE_RS17735	COG0432	Pfam Uncharacterised protein family UPF0047
BLTE_RS17750	COG2205	protein histidine kinase activity
BLTE_RS17750	COG0784	Response regulator, receiver
BLTE_RS17750	COG2198	Histidine kinase
BLTE_RS17760	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BLTE_RS17765	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BLTE_RS17785	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BLTE_RS17800	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BLTE_RS17830	COG1598	PFAM Uncharacterised protein family UPF0150
BLTE_RS17910	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)