locus-tag	class	description
BVIR_RS00005	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVIR_RS00015	COG0755	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVIR_RS00020	COG2386	Required for the export of heme to the periplasm for the biogenesis of c-type cytochromes
BVIR_RS00025	COG4133	protoheme IX ABC transporter activity
BVIR_RS00030	COG1048	Catalyzes the isomerization of citrate to isocitrate via cis-aconitate
BVIR_RS00065	COG0670	Belongs to the BI1 family
BVIR_RS00075	COG3127	ABC-type transport system involved in lysophospholipase L1, biosynthesis, permease component
BVIR_RS00080	COG4181	ATPase activity
BVIR_RS00090	COG1514	Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'- phosphomonoester
BVIR_RS00095	COG2154	pterin-4-alpha-carbinolamine dehydratase
BVIR_RS00110	COG2723	6-phospho-beta-galactosidase activity
BVIR_RS00120	COG0239	Important for reducing fluoride concentration in the cell, thus reducing its toxicity
BVIR_RS00125	COG1993	acr, cog1993
BVIR_RS00130	COG0300	oxidoreductase activity
BVIR_RS00145	COG0253	Catalyzes the stereoinversion of LL-2,6- diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso- DAP), a precursor of L-lysine and an essential component of the bacterial peptidoglycan
BVIR_RS00150	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVIR_RS00155	COG0501	Belongs to the peptidase M48B family
BVIR_RS00160	COG1704	LemA family
BVIR_RS00170	COG0227	Belongs to the bacterial ribosomal protein bL28 family
BVIR_RS00195	COG1329	Transcriptional regulator
BVIR_RS00210	COG4783	chaperone-mediated protein folding
BVIR_RS00235	COG0712	F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation
BVIR_RS00240	COG0056	Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit
BVIR_RS00245	COG0224	Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex
BVIR_RS00250	COG1764	response to oxidative stress
BVIR_RS00255	COG0055	Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits
BVIR_RS00260	COG0355	proton-transporting ATP synthase activity, rotational mechanism
BVIR_RS00270	COG0494	nUDIX hydrolase
BVIR_RS00285	COG0793	Belongs to the peptidase S41A family
BVIR_RS00295	COG1576	Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA
BVIR_RS00300	COG0799	negative regulation of ribosome biogenesis
BVIR_RS00305	COG1057	Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD)
BVIR_RS00310	COG0014	Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5- carboxylate
BVIR_RS00320	COG0263	Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate
BVIR_RS00325	COG0536	An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control
BVIR_RS00335	COG0211	Belongs to the bacterial ribosomal protein bL27 family
BVIR_RS00340	COG0261	This protein binds to 23S rRNA in the presence of protein L20
BVIR_RS00345	COG1132	(ABC) transporter
BVIR_RS00380	COG1678	Uncharacterized ACR, COG1678
BVIR_RS00390	COG0678	peroxiredoxin activity
BVIR_RS00390	COG0695	Has a glutathione-disulfide oxidoreductase activity in the presence of NADPH and glutathione reductase. Reduces low molecular weight disulfides and proteins
BVIR_RS00405	COG1611	Belongs to the LOG family
BVIR_RS00410	COG1309	transcriptional regulator
BVIR_RS00430	COG0604	alcohol dehydrogenase
BVIR_RS00440	COG2185	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BVIR_RS00440	COG1884	Catalyzes the reversible interconversion of isobutyryl- CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly
BVIR_RS00480	COG2989	Protein conserved in bacteria
BVIR_RS00500	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVIR_RS00510	COG1597	lipid kinase activity
BVIR_RS00515	COG0058	SHG alpha-glucan phosphorylase activity
BVIR_RS00520	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BVIR_RS00525	COG0448	Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans
BVIR_RS00530	COG0297	glycogen (starch) synthase activity
BVIR_RS00535	COG1523	belongs to the glycosyl hydrolase 13 family
BVIR_RS00545	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVIR_RS00550	COG1946	Acyl-CoA thioesterase
BVIR_RS00555	COG0347	Belongs to the P(II) protein family
BVIR_RS00560	COG0004	ammonium transporteR
BVIR_RS00565	COG1674	ftsk spoiiie
BVIR_RS00570	COG2834	Participates in the translocation of lipoproteins from the inner membrane to the outer membrane. Only forms a complex with a lipoprotein if the residue after the N-terminal Cys is not an aspartate (The Asp acts as a targeting signal to indicate that the lipoprotein should stay in the inner membrane)
BVIR_RS00580	COG0066	3-isopropylmalate dehydratase activity
BVIR_RS00595	COG0628	permease
BVIR_RS00615	COG5487	UPF0391 membrane protein
BVIR_RS00630	COG0784	Response regulator, receiver
BVIR_RS00640	COG3237	CsbD-like
BVIR_RS00660	COG0181	hydroxymethylbilane synthase activity
BVIR_RS00665	COG0533	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction
BVIR_RS00670	COG0240	glycerol-3-phosphate dehydrogenase [NAD(P)+] activity
BVIR_RS00685	COG2264	protein methyltransferase activity
BVIR_RS00690	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVIR_RS00695	COG1388	LysM domain
BVIR_RS00695	COG1376	ErfK ybiS ycfS ynhG family protein
BVIR_RS00700	COG2917	probably involved in intracellular septation
BVIR_RS00705	COG0552	protein localization to endoplasmic reticulum
BVIR_RS00710	COG0564	pseudouridine synthase activity
BVIR_RS00725	COG5394	Polyhydroxyalkanoate synthesis repressor PhaR
BVIR_RS00740	COG0697	spore germination
BVIR_RS00750	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVIR_RS00760	COG1742	UPF0060 membrane protein
BVIR_RS00765	COG0287	Prephenate dehydrogenase
BVIR_RS00770	COG0079	Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily
BVIR_RS00780	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVIR_RS00785	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVIR_RS00785	COG2813	Specifically methylates the guanine in position
BVIR_RS00820	COG2884	Cell division ATP-binding protein ftsE
BVIR_RS00830	COG0634	Belongs to the purine pyrimidine phosphoribosyltransferase family
BVIR_RS00845	COG0019	diaminopimelate decarboxylase activity
BVIR_RS00855	COG0165	Argininosuccinate lyase
BVIR_RS00860	COG0526	COG0526, thiol-disulfide isomerase and thioredoxins
BVIR_RS00865	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVIR_RS00870	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BVIR_RS00875	COG2086	electron transfer activity
BVIR_RS00880	COG0027	Involved in the de novo purine biosynthesis. Catalyzes the transfer of formate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR). Formate is provided by PurU via hydrolysis of 10-formyl-tetrahydrofolate
BVIR_RS00915	COG0333	Belongs to the bacterial ribosomal protein bL32 family
BVIR_RS00920	COG0744	Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors
BVIR_RS00930	COG3158	transport of potassium into the cell
BVIR_RS00935	COG0821	Converts 2C-methyl-D-erythritol 2,4-cyclodiphosphate (ME-2,4cPP) into 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate
BVIR_RS00940	COG0735	belongs to the Fur family
BVIR_RS00945	COG2110	phosphatase homologous to the C-terminal domain of histone macroH2A1
BVIR_RS00950	COG0443	Heat shock 70 kDa protein
BVIR_RS00960	COG0065	Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate
BVIR_RS00970	COG0335	large ribosomal subunit rRNA binding
BVIR_RS00985	COG0806	An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes
BVIR_RS00990	COG0228	four-way junction DNA binding
BVIR_RS00995	COG0541	Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY
BVIR_RS01010	COG0402	S-adenosylhomocysteine deaminase activity
BVIR_RS01015	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BVIR_RS01020	COG2267	carboxylic ester hydrolase activity
BVIR_RS01030	COG1181	Belongs to the D-alanine--D-alanine ligase family
BVIR_RS01040	COG0728	peptidoglycan biosynthetic process
BVIR_RS01045	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVIR_RS01055	COG0225	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVIR_RS01065	COG0817	Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group
BVIR_RS01070	COG0632	four-way junction helicase activity
BVIR_RS01080	COG0420	3'-5' exonuclease activity
BVIR_RS01095	COG1376	ErfK ybiS ycfS ynhG family protein
BVIR_RS01100	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA
BVIR_RS01100	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVIR_RS01115	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BVIR_RS01120	COG0518	GMP synthase (glutamine-hydrolyzing) activity
BVIR_RS01120	COG0519	Catalyzes the synthesis of GMP from XMP
BVIR_RS01125	COG4973	Belongs to the 'phage' integrase family. XerC subfamily
BVIR_RS01150	COG0483	inositol monophosphate 1-phosphatase activity
BVIR_RS01160	COG0352	thiamine-phosphate diphosphorylase activity
BVIR_RS01165	COG0126	phosphoglycerate kinase activity
BVIR_RS01185	COG0212	Belongs to the 5-formyltetrahydrofolate cyclo-ligase family
BVIR_RS01190	COG1692	metallophosphoesterase
BVIR_RS01195	COG3932	Exopolysaccharide synthesis, ExoD
BVIR_RS01205	COG0217	transcriptional regulatory protein
BVIR_RS01215	COG0765	amino acid transport
BVIR_RS01220	COG0765	amino acid transport
BVIR_RS01225	COG1126	abc transporter atp-binding protein
BVIR_RS01230	COG3264	Mechanosensitive ion channel
BVIR_RS01230	COG1196	nuclear chromosome segregation
BVIR_RS01240	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVIR_RS01245	COG0840	transmembrane signaling receptor activity
BVIR_RS01250	COG0523	cobalamin synthesis protein
BVIR_RS01255	COG1686	Belongs to the peptidase S11 family
BVIR_RS01270	COG1132	(ABC) transporter
BVIR_RS01280	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVIR_RS01350	COG1344	Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella
BVIR_RS01360	COG0457	Tetratricopeptide repeat
BVIR_RS01360	COG0463	Glycosyl transferase, family 2
BVIR_RS01380	COG0703	Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate
BVIR_RS01390	COG4974	Belongs to the 'phage' integrase family
BVIR_RS01395	COG0825	malonyl-CoA metabolic process
BVIR_RS01400	COG3034	peptidoglycan biosynthetic process
BVIR_RS01410	COG0653	protein targeting
BVIR_RS01415	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVIR_RS01420	COG1364	Catalyzes two activities which are involved in the cyclic version of arginine biosynthesis the synthesis of N- acetylglutamate from glutamate and acetyl-CoA as the acetyl donor, and of ornithine by transacetylation between N(2)-acetylornithine and glutamate
BVIR_RS01425	COG0494	nUDIX hydrolase
BVIR_RS01440	COG2226	methyltransferase
BVIR_RS01445	COG1040	competence protein
BVIR_RS01455	COG0388	Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source
BVIR_RS01465	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVIR_RS01490	COG0216	Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA
BVIR_RS01495	COG2890	protein-(glutamine-N5) methyltransferase activity
BVIR_RS01510	COG0542	response to heat
BVIR_RS01520	COG0739	heme binding
BVIR_RS01600	COG0009	L-threonylcarbamoyladenylate synthase
BVIR_RS01610	COG1132	(ABC) transporter
BVIR_RS01640	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS01740	COG0450	alkyl hydroperoxide reductase
BVIR_RS01745	COG0599	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVIR_RS01765	COG0800	Aldolase
BVIR_RS01775	COG3300	MHYT domain
BVIR_RS01775	COG5001	Diguanylate cyclase
BVIR_RS01790	COG0626	cystathionine gamma-synthase activity
BVIR_RS01805	COG1135	Part of the ABC transporter complex MetNIQ involved in methionine import. Responsible for energy coupling to the transport system
BVIR_RS01810	COG2011	ABC-type metal ion transport system permease component
BVIR_RS01815	COG1464	Belongs to the NlpA lipoprotein family
BVIR_RS01825	COG1541	Catalyzes the activation of phenylacetic acid (PA) to phenylacetyl-CoA (PA-CoA)
BVIR_RS01830	COG1960	acyl-CoA dehydrogenase activity
BVIR_RS01840	COG0183	Belongs to the thiolase family
BVIR_RS01850	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVIR_RS01865	COG2890	protein-(glutamine-N5) methyltransferase activity
BVIR_RS01890	COG2226	methyltransferase
BVIR_RS01895	COG0685	methylenetetrahydrofolate reductase (NAD(P)H) activity
BVIR_RS01920	COG1966	Carbon starvation protein
BVIR_RS01930	COG3023	N-Acetylmuramoyl-L-alanine amidase
BVIR_RS01935	COG1076	Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA
BVIR_RS01940	COG2001	Belongs to the MraZ family
BVIR_RS01945	COG0275	rRNA processing
BVIR_RS01960	COG0769	Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan
BVIR_RS01965	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVIR_RS01970	COG0771	Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA)
BVIR_RS01980	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVIR_RS01985	COG0773	UDP-N-acetylmuramate-L-alanine ligase activity
BVIR_RS02000	COG0812	UDP-N-acetylmuramate dehydrogenase activity
BVIR_RS02005	COG1589	Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly
BVIR_RS02010	COG0849	cell division
BVIR_RS02015	COG0206	Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity
BVIR_RS02025	COG4105	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVIR_RS02035	COG0272	DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA
BVIR_RS02040	COG2197	response regulator
BVIR_RS02050	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BVIR_RS02055	COG1278	Cold shock
BVIR_RS02070	COG0853	Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine
BVIR_RS02080	COG0006	proline dipeptidase activity
BVIR_RS02085	COG4095	Psort location CytoplasmicMembrane, score
BVIR_RS02090	COG1278	Cold shock
BVIR_RS02100	COG0040	Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of hisG enzymatic activity
BVIR_RS02105	COG3705	Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine
BVIR_RS02115	COG0394	Belongs to the low molecular weight phosphotyrosine protein phosphatase family
BVIR_RS02120	COG3001	Fructosamine kinase
BVIR_RS02125	COG3263	regulation of cellular component size
BVIR_RS02140	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVIR_RS02150	COG3131	Involved in the biosynthesis of osmoregulated periplasmic glucans (OPGs)
BVIR_RS02155	COG2943	transferase activity, transferring hexosyl groups
BVIR_RS02160	COG2003	Belongs to the UPF0758 family
BVIR_RS02165	COG0024	Methionine aminopeptidase
BVIR_RS02180	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVIR_RS02200	COG0189	ligase activity
BVIR_RS02205	COG0456	acetyltransferase
BVIR_RS02205	COG1214	PFAM Peptidase M22, glycoprotease
BVIR_RS02220	COG2215	Belongs to the NiCoT transporter (TC 2.A.52) family
BVIR_RS02230	COG1013	pyruvate-flavodoxin oxidoreductase activity
BVIR_RS02235	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BVIR_RS02235	COG0674	pyruvate-flavodoxin oxidoreductase activity
BVIR_RS02265	COG0559	Belongs to the binding-protein-dependent transport system permease family
BVIR_RS02270	COG0683	leucine binding
BVIR_RS02275	COG2050	protein possibly involved in aromatic compounds catabolism
BVIR_RS02310	COG1218	3'(2'),5'-bisphosphate nucleotidase
BVIR_RS02320	COG0643	Histidine kinase
BVIR_RS02320	COG0784	Response regulator, receiver
BVIR_RS02320	COG2198	Histidine kinase
BVIR_RS02335	COG2201	protein-glutamate methylesterase activity
BVIR_RS02340	COG1352	Methylation of the membrane-bound methyl-accepting chemotaxis proteins (MCP) to form gamma-glutamyl methyl ester residues in MCP
BVIR_RS02350	COG0745	RESPONSE REGULATOR receiver
BVIR_RS02365	COG4106	trans-aconitate 2-methyltransferase activity
BVIR_RS02375	COG4566	intracellular signal transduction
BVIR_RS02415	COG3005	denitrification pathway
BVIR_RS02420	COG5433	transposase activity
BVIR_RS02430	COG0293	Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit
BVIR_RS02435	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BVIR_RS02445	COG2367	Beta-lactamase
BVIR_RS02450	COG0840	transmembrane signaling receptor activity
BVIR_RS02460	COG0745	RESPONSE REGULATOR receiver
BVIR_RS02465	COG2198	Histidine kinase
BVIR_RS02465	COG0643	Histidine kinase
BVIR_RS02470	COG0835	chemotaxis
BVIR_RS02475	COG0840	transmembrane signaling receptor activity
BVIR_RS02480	COG0835	chemotaxis
BVIR_RS02490	COG2201	protein-glutamate methylesterase activity
BVIR_RS02495	COG1871	Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis
BVIR_RS02510	COG0071	Belongs to the small heat shock protein (HSP20) family
BVIR_RS02520	COG1762	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVIR_RS02525	COG1544	Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase
BVIR_RS02530	COG1508	bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding
BVIR_RS02535	COG1137	ATPase activity
BVIR_RS02540	COG1934	Involved in the assembly of lipopolysaccharide (LPS). Required for the translocation of LPS from the inner membrane to the outer membrane. May form a bridge between the inner membrane and the outer membrane, via interactions with LptC and LptD, thereby facilitating LPS transfer across the periplasm
BVIR_RS02570	COG5001	Diguanylate cyclase
BVIR_RS02570	COG3300	MHYT domain
BVIR_RS02575	COG0101	tRNA pseudouridine synthase activity
BVIR_RS02585	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVIR_RS02590	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BVIR_RS02605	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BVIR_RS02605	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BVIR_RS02620	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BVIR_RS02630	COG0624	Catalyzes the hydrolysis of N-succinyl-L,L- diaminopimelic acid (SDAP), forming succinate and LL-2,6- diaminoheptanedioate (DAP), an intermediate involved in the bacterial biosynthesis of lysine and meso-diaminopimelic acid, an essential component of bacterial cell walls
BVIR_RS02635	COG2171	N-acyltransferase activity
BVIR_RS02645	COG0548	Belongs to the acetylglutamate kinase family. ArgB subfamily
BVIR_RS02655	COG2197	response regulator
BVIR_RS02660	COG2197	response regulator
BVIR_RS02675	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVIR_RS02685	COG4566	intracellular signal transduction
BVIR_RS02690	COG4191	Histidine kinase
BVIR_RS02695	COG1122	ATPase activity
BVIR_RS02700	COG0619	Transmembrane (T) component of an energy-coupling factor (ECF) ABC-transporter complex. Unlike classic ABC transporters this ECF transporter provides the energy necessary to transport a number of different substrates
BVIR_RS02705	COG1268	BioY protein
BVIR_RS02710	COG0151	Belongs to the GarS family
BVIR_RS02720	COG1968	undecaprenyl-diphosphatase activity
BVIR_RS02725	COG0268	Binds directly to 16S ribosomal RNA
BVIR_RS02730	COG0593	it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box) 5'-TTATC CA A CA A-3'. DnaA binds to ATP and to acidic phospholipids
BVIR_RS02740	COG1195	it is required for DNA replication and normal SOS inducibility. RecF binds preferentially to single-stranded, linear DNA. It also seems to bind ATP
BVIR_RS02745	COG0156	8-amino-7-oxononanoate synthase activity
BVIR_RS02750	COG1349	DNA-binding transcription factor activity
BVIR_RS02755	COG2226	methyltransferase
BVIR_RS02765	COG0644	oxidoreductase
BVIR_RS02770	COG2211	Major facilitator Superfamily
BVIR_RS02775	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BVIR_RS02795	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS02800	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS02805	COG1429	ligase activity, forming nitrogen-metal bonds
BVIR_RS02810	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BVIR_RS02845	COG0036	Belongs to the ribulose-phosphate 3-epimerase family
BVIR_RS02890	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BVIR_RS02900	COG1240	Involved in chlorophyll biosynthesis. Catalyzes the insertion of magnesium ion into protoporphyrin IX to yield Mg- protoporphyrin IX
BVIR_RS02910	COG1233	COG1233 Phytoene dehydrogenase and related
BVIR_RS02915	COG1562	ergosterol biosynthetic process
BVIR_RS02930	COG0142	geranyltranstransferase activity
BVIR_RS02935	COG1063	alcohol dehydrogenase
BVIR_RS02940	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BVIR_RS02945	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS02950	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS02985	COG0367	asparagine synthase
BVIR_RS02995	COG0180	Tryptophanyl-tRNA synthetase
BVIR_RS03005	COG0694	Involved in iron-sulfur cluster biogenesis. Binds a 4Fe- 4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe S proteins. Could also act as a scaffold chaperone for damaged Fe S proteins
BVIR_RS03030	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVIR_RS03035	COG1702	phosphate starvation-inducible protein PhoH
BVIR_RS03045	COG1253	flavin adenine dinucleotide binding
BVIR_RS03050	COG0815	Transfers the fatty acyl group on membrane lipoproteins
BVIR_RS03055	COG1396	sequence-specific DNA binding
BVIR_RS03060	COG0192	Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme
BVIR_RS03065	COG0220	tRNA (guanine-N7-)-methyltransferase activity
BVIR_RS03085	COG2176	DNA-directed DNA polymerase activity
BVIR_RS03090	COG5002	protein histidine kinase activity
BVIR_RS03090	COG2176	DNA-directed DNA polymerase activity
BVIR_RS03100	COG2205	protein histidine kinase activity
BVIR_RS03120	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVIR_RS03125	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVIR_RS03130	COG0564	pseudouridine synthase activity
BVIR_RS03145	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVIR_RS03155	COG1898	dTDP-4-dehydrorhamnose 3,5-epimerase activity
BVIR_RS03165	COG0684	Catalyzes the aldol cleavage of 4-hydroxy-4-methyl-2- oxoglutarate (HMG) into 2 molecules of pyruvate. Also contains a secondary oxaloacetate (OAA) decarboxylase activity due to the common pyruvate enolate transition state formed following C-C bond cleavage in the retro-aldol and decarboxylation reactions
BVIR_RS03165	COG0473	3-isopropylmalate dehydrogenase activity
BVIR_RS03205	COG0438	transferase activity, transferring glycosyl groups
BVIR_RS03210	COG0004	ammonium transporteR
BVIR_RS03220	COG0628	permease
BVIR_RS03225	COG0413	3-methyl-2-oxobutanoate hydroxymethyltransferase activity
BVIR_RS03245	COG1160	GTP binding
BVIR_RS03250	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS03255	COG0034	Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine
BVIR_RS03270	COG0787	Catalyzes the interconversion of L-alanine and D- alanine. May also act on other amino acids
BVIR_RS03275	COG0305	Participates in initiation and elongation during chromosome replication
BVIR_RS03280	COG0359	binds to the 23S rRNA
BVIR_RS03290	COG0238	Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit
BVIR_RS03295	COG0360	Binds together with S18 to 16S ribosomal RNA
BVIR_RS03300	COG0331	[acyl-carrier-protein] S-malonyltransferase activity
BVIR_RS03315	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVIR_RS03320	COG1559	Functions as a peptidoglycan terminase that cleaves nascent peptidoglycan strands endolytically to terminate their elongation
BVIR_RS03325	COG1561	YicC-like family, N-terminal region
BVIR_RS03330	COG0194	GDP metabolic process
BVIR_RS03335	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVIR_RS03340	COG1995	Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)
BVIR_RS03350	COG1452	involved in the assembly of lipopolysaccharide (LPS) at the surface of the outer membrane
BVIR_RS03365	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BVIR_RS03390	COG0488	(ABC) transporter
BVIR_RS03410	COG4148	Part of the ABC transporter complex ModABC involved in molybdenum import. Responsible for energy coupling to the transport system
BVIR_RS03415	COG4149	molybdate abc transporter
BVIR_RS03420	COG0725	ABC transporter, periplasmic molybdate-binding protein
BVIR_RS03425	COG0461	Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP)
BVIR_RS03430	COG0418	dihydroorotase activity
BVIR_RS03450	COG1573	uracil-dna glycosylase
BVIR_RS03465	COG1022	Amp-dependent synthetase and ligase
BVIR_RS03500	COG0276	Catalyzes the ferrous insertion into protoporphyrin IX
BVIR_RS03520	COG2225	Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl-CoA) and glyoxylate to form malate and CoA
BVIR_RS03560	COG1556	Lactate utilization protein
BVIR_RS03565	COG1139	Iron-sulfur cluster binding protein
BVIR_RS03570	COG0247	lactate metabolic process
BVIR_RS03585	COG0521	Mo-molybdopterin cofactor biosynthetic process
BVIR_RS03595	COG3920	Histidine kinase
BVIR_RS03605	COG0129	dihydroxy-acid dehydratase activity
BVIR_RS03610	COG0766	Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine
BVIR_RS03620	COG0141	Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine
BVIR_RS03625	COG5328	Belongs to the UPF0262 family
BVIR_RS03640	COG0424	maF-like protein
BVIR_RS03645	COG3024	Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C-terminal domain of GyrB, which probably disrupts DNA binding by the gyrase
BVIR_RS03650	COG1570	exodeoxyribonuclease VII activity
BVIR_RS03660	COG1663	tetraacyldisaccharide 4'-kinase activity
BVIR_RS03665	COG1519	Transferase
BVIR_RS03680	COG0312	modulator of DNA gyrase
BVIR_RS03690	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BVIR_RS03700	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BVIR_RS03720	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS03735	COG0625	glutathione transferase activity
BVIR_RS03740	COG2961	Specifically methylates the adenine in position 2030 of 23S rRNA
BVIR_RS03770	COG0257	Belongs to the bacterial ribosomal protein bL36 family
BVIR_RS03780	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BVIR_RS03785	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BVIR_RS03805	COG1376	ErfK ybiS ycfS ynhG family protein
BVIR_RS03855	COG0818	Recycling of diacylglycerol produced during the turnover of membrane phospholipid
BVIR_RS03860	COG3200	phospho-2-dehydro-3-deoxyheptonate aldolase
BVIR_RS03880	COG0120	Catalyzes the reversible conversion of ribose-5- phosphate to ribulose 5-phosphate
BVIR_RS03885	COG0546	phosphoglycolate phosphatase activity
BVIR_RS03900	COG4663	Part of the tripartite ATP-independent periplasmic (TRAP) transport system
BVIR_RS03905	COG3045	CreA protein
BVIR_RS03920	COG0215	cysteine-tRNA ligase activity
BVIR_RS03930	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVIR_RS03940	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVIR_RS03945	COG1573	uracil-dna glycosylase
BVIR_RS03955	COG1758	RNA polymerase activity
BVIR_RS03965	COG0854	Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino-2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate
BVIR_RS03970	COG0736	holo-[acyl-carrier-protein] synthase activity
BVIR_RS03975	COG0681	Belongs to the peptidase S26 family
BVIR_RS03980	COG0571	ribonuclease III activity
BVIR_RS03985	COG1159	An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism
BVIR_RS03995	COG1381	Involved in DNA repair and RecF pathway recombination
BVIR_RS04010	COG3318	Belongs to the UPF0149 family
BVIR_RS04010	COG3012	SEC-C Motif Domain Protein
BVIR_RS04015	COG4191	Histidine kinase
BVIR_RS04020	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVIR_RS04035	COG2989	Protein conserved in bacteria
BVIR_RS04055	COG1024	Enoyl-CoA hydratase
BVIR_RS04070	COG0113	porphobilinogen synthase activity
BVIR_RS04115	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVIR_RS04125	COG1291	archaeal or bacterial-type flagellum-dependent cell motility
BVIR_RS04140	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVIR_RS04155	COG5433	transposase activity
BVIR_RS04160	COG2038	nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase activity
BVIR_RS04170	COG2202	Pas domain
BVIR_RS04170	COG2205	protein histidine kinase activity
BVIR_RS04205	COG0625	glutathione transferase activity
BVIR_RS04215	COG3300	MHYT domain
BVIR_RS04215	COG5001	Diguanylate cyclase
BVIR_RS04220	COG0840	transmembrane signaling receptor activity
BVIR_RS04225	COG0436	Aminotransferase
BVIR_RS04235	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVIR_RS04240	COG2041	Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide
BVIR_RS04245	COG0583	DNA-binding transcription factor activity
BVIR_RS04250	COG0492	ferredoxin-NADP+ reductase activity
BVIR_RS04260	COG1522	sequence-specific DNA binding
BVIR_RS04270	COG0782	Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus
BVIR_RS04275	COG0458	carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity
BVIR_RS04290	COG1012	belongs to the aldehyde dehydrogenase family
BVIR_RS04300	COG1835	transferase activity, transferring acyl groups other than amino-acyl groups
BVIR_RS04305	COG2951	lytic endotransglycosylase activity
BVIR_RS04320	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS04325	COG4618	COG4618 ABC-type protease lipase transport system, ATPase and permease components
BVIR_RS04355	COG0568	sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released
BVIR_RS04360	COG0358	DNA primase activity
BVIR_RS04375	COG0505	Belongs to the CarA family
BVIR_RS04400	COG0778	Nitroreductase
BVIR_RS04415	COG1846	Transcriptional regulator
BVIR_RS04420	COG0451	ADP-glyceromanno-heptose 6-epimerase activity
BVIR_RS04445	COG0171	NAD+ synthase (glutamine-hydrolyzing) activity
BVIR_RS04450	COG0318	PFAM AMP-dependent synthetase and ligase
BVIR_RS04460	COG0367	asparagine synthase
BVIR_RS04490	COG1165	Catalyzes the thiamine diphosphate-dependent decarboxylation of 2-oxoglutarate and the subsequent addition of the resulting succinic semialdehyde-thiamine pyrophosphate anion to isochorismate to yield 2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylate (SEPHCHC)
BVIR_RS04495	COG1169	isochorismate synthase
BVIR_RS04500	COG0438	transferase activity, transferring glycosyl groups
BVIR_RS04520	COG0472	First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan
BVIR_RS04530	COG0546	phosphoglycolate phosphatase activity
BVIR_RS04540	COG1132	(ABC) transporter
BVIR_RS04545	COG0176	Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway
BVIR_RS04555	COG0673	inositol 2-dehydrogenase activity
BVIR_RS04565	COG0728	peptidoglycan biosynthetic process
BVIR_RS04580	COG0697	spore germination
BVIR_RS04590	COG2145	Catalyzes the phosphorylation of the hydroxyl group of 4-methyl-5-beta-hydroxyethylthiazole (THZ)
BVIR_RS04595	COG0352	thiamine-phosphate diphosphorylase activity
BVIR_RS04600	COG0351	phosphomethylpyrimidine kinase
BVIR_RS04605	COG1396	sequence-specific DNA binding
BVIR_RS04610	COG1309	transcriptional regulator
BVIR_RS04615	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS04625	COG0179	Fumarylacetoacetate (FAA) hydrolase
BVIR_RS04640	COG0707	Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II)
BVIR_RS04660	COG4948	Mandelate Racemase Muconate Lactonizing
BVIR_RS04670	COG0767	ABC-type transport system involved in resistance to organic solvents, permease component
BVIR_RS04675	COG1127	ABC transporter
BVIR_RS04680	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVIR_RS04680	COG3218	ABC-type transport auxiliary lipoprotein component
BVIR_RS04685	COG3218	ABC-type transport auxiliary lipoprotein component
BVIR_RS04685	COG1463	ABC-type transport system involved in resistance to organic solvents, periplasmic component
BVIR_RS04710	COG0633	Ferredoxin
BVIR_RS04720	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS04725	COG0492	ferredoxin-NADP+ reductase activity
BVIR_RS04730	COG2226	methyltransferase
BVIR_RS04735	COG1295	ribonuclease BN
BVIR_RS04765	COG3637	Has lipid A 3-O-deacylase activity. Hydrolyzes the ester bond at the 3 position of lipid A, a bioactive component of lipopolysaccharide (LPS), thereby releasing the primary fatty acyl moiety
BVIR_RS04790	COG3768	UPF0283 membrane protein
BVIR_RS04795	COG3106	COG3106 Predicted ATPase
BVIR_RS04805	COG0665	tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase activity
BVIR_RS04810	COG3655	Transcriptional regulator
BVIR_RS04845	COG1706	bacterial-type flagellum-dependent cell motility
BVIR_RS04870	COG4786	Flagellar basal body rod
BVIR_RS04875	COG4786	Flagellar basal body rod
BVIR_RS04905	COG1338	Plays a role in the flagellum-specific transport system
BVIR_RS04915	COG1815	bacterial-type flagellum-dependent cell motility
BVIR_RS04920	COG1558	bacterial-type flagellum-dependent cell motility
BVIR_RS04925	COG1677	Flagellar hook-basal body complex protein FliE
BVIR_RS04930	COG1987	bacterial-type flagellum assembly
BVIR_RS04935	COG1684	flagellar biosynthetic protein fliR
BVIR_RS04940	COG1377	Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVIR_RS04960	COG0013	Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain
BVIR_RS04970	COG0538	isocitrate dehydrogenase activity
BVIR_RS04985	COG0796	Provides the (R)-glutamate required for cell wall biosynthesis
BVIR_RS04990	COG0522	One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit
BVIR_RS04995	COG0278	Belongs to the glutaredoxin family. Monothiol subfamily
BVIR_RS05005	COG0046	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVIR_RS05015	COG0047	phosphoribosylformylglycinamidine synthase activity
BVIR_RS05020	COG1828	Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the ammonia molecule from PurQ to PurL
BVIR_RS05025	COG0152	phosphoribosylaminoimidazolesuccinocarboxamide synthase activity
BVIR_RS05035	COG0015	Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily
BVIR_RS05050	COG0174	glutamine synthetase
BVIR_RS05055	COG0347	Belongs to the P(II) protein family
BVIR_RS05060	COG0062	Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration
BVIR_RS05060	COG0063	ADP-dependent NAD(P)H-hydrate dehydratase activity
BVIR_RS05075	COG0544	peptidyl-prolyl cis-trans isomerase activity
BVIR_RS05085	COG1219	ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP
BVIR_RS05090	COG0466	ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner
BVIR_RS05095	COG0776	regulation of translation
BVIR_RS05135	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS05140	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVIR_RS05145	COG0304	beta-ketoacyl-acyl-carrier-protein synthase II activity
BVIR_RS05150	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVIR_RS05155	COG0236	Carrier of the growing fatty acid chain in fatty acid biosynthesis
BVIR_RS05160	COG5433	transposase activity
BVIR_RS05165	COG0651	ATP synthesis coupled electron transport
BVIR_RS05170	COG0650	Formate hydrogenlyase subunit 4
BVIR_RS05180	COG0651	ATP synthesis coupled electron transport
BVIR_RS05190	COG3260	NADH ubiquinone oxidoreductase 20
BVIR_RS05200	COG1802	Transcriptional regulator
BVIR_RS05215	COG0105	UTP biosynthetic process
BVIR_RS05220	COG0861	Integral membrane protein TerC family
BVIR_RS05235	COG0299	Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate
BVIR_RS05240	COG0150	phosphoribosylformylglycinamidine cyclo-ligase activity
BVIR_RS05250	COG0628	permease
BVIR_RS05260	COG0855	Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP)
BVIR_RS05265	COG0248	Ppx GppA phosphatase
BVIR_RS05270	COG0349	Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides
BVIR_RS05275	COG0173	Aspartyl-tRNA synthetase with relaxed tRNA specificity since it is able to aspartylate not only its cognate tRNA(Asp) but also tRNA(Asn). Reaction proceeds in two steps L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp Asn)
BVIR_RS05280	COG2200	EAL domain
BVIR_RS05290	COG1346	cytolysis
BVIR_RS05335	COG1393	Belongs to the ArsC family
BVIR_RS05345	COG1598	PFAM Uncharacterised protein family UPF0150
BVIR_RS05360	COG0209	Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides
BVIR_RS05380	COG2360	Functions in the N-end rule pathway of protein degradation where it conjugates Leu, Phe and, less efficiently, Met from aminoacyl-tRNAs to the N-termini of proteins containing an N-terminal arginine or lysine
BVIR_RS05385	COG0439	Biotin carboxylase
BVIR_RS05390	COG0511	ligase activity, forming carbon-carbon bonds
BVIR_RS05405	COG0436	Aminotransferase
BVIR_RS05410	COG1530	ribonuclease E activity
BVIR_RS05410	COG1530	ribonuclease E activity
BVIR_RS05415	COG0860	N-Acetylmuramoyl-L-alanine amidase
BVIR_RS05430	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS05435	COG0842	Transport permease protein
BVIR_RS05435	COG1129	ABC transporter
BVIR_RS05440	COG0842	Transport permease protein
BVIR_RS05445	COG1350	The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine
BVIR_RS05455	COG0840	transmembrane signaling receptor activity
BVIR_RS05460	COG5433	transposase activity
BVIR_RS05475	COG2326	polyphosphate kinase activity
BVIR_RS05480	COG0739	heme binding
BVIR_RS05485	COG1225	Alkyl hydroperoxide reductase Thiol specific antioxidant Mal allergen
BVIR_RS05495	COG0162	Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two-step reaction tyrosine is first activated by ATP to form Tyr- AMP and then transferred to the acceptor end of tRNA(Tyr)
BVIR_RS05500	COG2377	Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling
BVIR_RS05505	COG3284	Transcriptional regulator
BVIR_RS05510	COG1012	belongs to the aldehyde dehydrogenase family
BVIR_RS05515	COG1454	alcohol dehydrogenase
BVIR_RS05520	COG3237	CsbD-like
BVIR_RS05525	COG1278	Cold shock
BVIR_RS05545	COG2945	thiolester hydrolase activity
BVIR_RS05550	COG1104	cysteine desulfurase activity
BVIR_RS05555	COG0719	Fe-S assembly protein
BVIR_RS05565	COG0396	ATPase activity
BVIR_RS05575	COG0719	Fe-S assembly protein
BVIR_RS05580	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVIR_RS05585	COG2151	metal-sulfur cluster biosynthetic enzyme
BVIR_RS05590	COG0316	Belongs to the HesB IscA family
BVIR_RS05600	COG0513	Belongs to the DEAD box helicase family
BVIR_RS05605	COG1638	TRAP-type C4-dicarboxylate transport system periplasmic component
BVIR_RS05615	COG1593	TRAP-type C4-dicarboxylate transport system, large permease component
BVIR_RS05615	COG3090	Trap-type c4-dicarboxylate transport system, small permease component
BVIR_RS05640	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BVIR_RS05645	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVIR_RS05650	COG4558	Periplasmic binding protein
BVIR_RS05670	COG0667	Aldo Keto reductase
BVIR_RS05675	COG2814	Major facilitator Superfamily
BVIR_RS05705	COG1073	alpha beta
BVIR_RS05825	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVIR_RS05985	COG1475	DNA binding
BVIR_RS06015	COG1061	Type III restriction enzyme res subunit
BVIR_RS06135	COG2301	Belongs to the HpcH HpaI aldolase family
BVIR_RS06140	COG2030	dehydratase
BVIR_RS06165	COG0061	Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP
BVIR_RS06170	COG1324	tolerance protein
BVIR_RS06190	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BVIR_RS06200	COG3638	Part of the ABC transporter complex PhnCDE involved in phosphonates import. Responsible for energy coupling to the transport system
BVIR_RS06210	COG3639	organic phosphonate transmembrane transporter activity
BVIR_RS06215	COG3639	organic phosphonate transmembrane transporter activity
BVIR_RS06220	COG2188	Transcriptional regulator
BVIR_RS06225	COG3624	Phosphonate C-P lyase system protein PhnG
BVIR_RS06230	COG3625	alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase activity
BVIR_RS06235	COG3626	phosphonate metabolism
BVIR_RS06240	COG3627	carbon phosphorus lyase activity
BVIR_RS06245	COG4107	phosphonate C-P lyase system protein PhnK
BVIR_RS06250	COG4778	phosphonate C-P lyase system protein PhnL
BVIR_RS06255	COG3454	Phosphonate metabolism
BVIR_RS06260	COG3709	Catalyzes the phosphorylation of ribose 1,5-bisphosphate to 5-phospho-D-ribosyl alpha-1-diphosphate (PRPP)
BVIR_RS06270	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVIR_RS06275	COG1120	ATPase activity
BVIR_RS06295	COG1270	Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group
BVIR_RS06310	COG0438	transferase activity, transferring glycosyl groups
BVIR_RS06330	COG0459	protein refolding
BVIR_RS06335	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BVIR_RS06340	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS06345	COG5425	PFAM Usg family protein
BVIR_RS06350	COG3932	Exopolysaccharide synthesis, ExoD
BVIR_RS06355	COG0602	queuosine metabolic process
BVIR_RS06360	COG0720	synthase
BVIR_RS06380	COG2308	Evidence 4 Homologs of previously reported genes of
BVIR_RS06385	COG1058	Belongs to the CinA family
BVIR_RS06385	COG1546	Belongs to the CinA family
BVIR_RS06390	COG1136	(ABC) transporter
BVIR_RS06390	COG0577	efflux transmembrane transporter activity
BVIR_RS06395	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS06410	COG0838	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVIR_RS06415	COG0377	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVIR_RS06420	COG0852	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVIR_RS06425	COG0649	NAD binding
BVIR_RS06430	COG1905	PFAM NADH dehydrogenase (ubiquinone) 24 kDa subunit
BVIR_RS06435	COG1894	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain
BVIR_RS06445	COG1005	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient. This subunit may bind ubiquinone
BVIR_RS06455	COG1143	NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient
BVIR_RS06465	COG0713	ATP synthesis coupled electron transport
BVIR_RS06480	COG1007	ATP synthesis coupled electron transport
BVIR_RS06495	COG0346	lactoylglutathione lyase activity
BVIR_RS06500	COG0442	prolyl-tRNA aminoacylation
BVIR_RS06510	COG1136	(ABC) transporter
BVIR_RS06515	COG0415	Belongs to the DNA photolyase family
BVIR_RS06520	COG1522	sequence-specific DNA binding
BVIR_RS06525	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVIR_RS06535	COG5433	transposase activity
BVIR_RS06555	COG1024	Enoyl-CoA hydratase
BVIR_RS06585	COG3585	molybdate ion transport
BVIR_RS06595	COG3608	succinylglutamate desuccinylase aspartoacylase
BVIR_RS06595	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BVIR_RS06600	COG3476	COG3476 Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog)
BVIR_RS06615	COG0250	Participates in transcription elongation, termination and antitermination
BVIR_RS06620	COG0080	Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors
BVIR_RS06625	COG0081	regulation of translation
BVIR_RS06630	COG0244	Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors
BVIR_RS06635	COG0222	ribosome binding
BVIR_RS06640	COG0085	RNA polymerase activity
BVIR_RS06645	COG0086	DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates
BVIR_RS06655	COG0048	Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit
BVIR_RS06660	COG0049	tRNA binding
BVIR_RS06665	COG0480	Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome
BVIR_RS06670	COG0050	This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis
BVIR_RS06675	COG0051	transcription antitermination factor activity, RNA binding
BVIR_RS06680	COG0087	One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit
BVIR_RS06685	COG0088	Forms part of the polypeptide exit tunnel
BVIR_RS06690	COG0089	rRNA binding
BVIR_RS06695	COG0090	One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity
BVIR_RS06700	COG0185	Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA
BVIR_RS06705	COG0091	The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome
BVIR_RS06710	COG0092	Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation
BVIR_RS06715	COG0197	Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs
BVIR_RS06720	COG0255	Belongs to the universal ribosomal protein uL29 family
BVIR_RS06725	COG0186	One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA
BVIR_RS06730	COG0093	Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome
BVIR_RS06735	COG0198	One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit
BVIR_RS06740	COG0094	This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits
BVIR_RS06745	COG0199	Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site
BVIR_RS06750	COG0096	One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit
BVIR_RS06755	COG0097	This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7 L12 stalk, and near the tRNA binding site of the peptidyltransferase center
BVIR_RS06760	COG0256	This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance
BVIR_RS06765	COG0098	Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body
BVIR_RS06770	COG1841	ribosomal large subunit assembly
BVIR_RS06775	COG0200	Binds to the 23S rRNA
BVIR_RS06780	COG0201	protein transport
BVIR_RS06785	COG0563	adenylate kinase activity
BVIR_RS06790	COG0099	Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits
BVIR_RS06795	COG0100	Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome
BVIR_RS06800	COG0202	RNA polymerase activity
BVIR_RS06805	COG0203	ribosomal protein L17
BVIR_RS06815	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVIR_RS06820	COG2256	atpase related to the helicase subunit of the holliday junction resolvase
BVIR_RS06825	COG0564	pseudouridine synthase activity
BVIR_RS06835	COG0546	phosphoglycolate phosphatase activity
BVIR_RS06850	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVIR_RS06860	COG0346	lactoylglutathione lyase activity
BVIR_RS06870	COG4770	biotin carboxylase activity
BVIR_RS06875	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVIR_RS06885	COG1254	Belongs to the acylphosphatase family
BVIR_RS06890	COG0321	lipoyl(octanoyl) transferase activity
BVIR_RS06910	COG1404	Belongs to the peptidase S8 family
BVIR_RS06915	COG1960	acyl-CoA dehydrogenase activity
BVIR_RS06920	COG3300	MHYT domain
BVIR_RS06920	COG5001	Diguanylate cyclase
BVIR_RS06925	COG2239	Acts as a magnesium transporter
BVIR_RS06930	COG0726	polysaccharide deacetylase
BVIR_RS06940	COG0603	Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))
BVIR_RS06950	COG1434	Gram-negative-bacterium-type cell wall biogenesis
BVIR_RS06965	COG0625	glutathione transferase activity
BVIR_RS06970	COG4799	Acetyl-CoA carboxylase, carboxyltransferase component subunits alpha and beta
BVIR_RS06985	COG0561	phosphatase activity
BVIR_RS06990	COG1850	ribulose-bisphosphate carboxylase activity
BVIR_RS07020	COG0583	DNA-binding transcription factor activity
BVIR_RS07025	COG2855	membrane
BVIR_RS07030	COG3033	Beta-eliminating lyase
BVIR_RS07055	COG0414	Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate
BVIR_RS07060	COG0489	protein tyrosine kinase activity
BVIR_RS07075	COG1686	Belongs to the peptidase S11 family
BVIR_RS07095	COG2127	Involved in the modulation of the specificity of the ClpAP-mediated ATP-dependent protein degradation
BVIR_RS07115	COG0537	adenosine 5'-monophosphoramidase activity
BVIR_RS07125	COG2197	response regulator
BVIR_RS07130	COG3916	Acyl-homoserine-lactone synthase
BVIR_RS07165	COG1342	Belongs to the UPF0251 family
BVIR_RS07230	COG1002	Type II restriction enzyme, methylase subunits
BVIR_RS07265	COG5433	transposase activity
BVIR_RS07275	COG0566	Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family
BVIR_RS07295	COG4166	transmembrane transport
BVIR_RS07310	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BVIR_RS07315	COG0449	glutamine-fructose-6-phosphate transaminase (isomerizing) activity
BVIR_RS07325	COG2832	Protein of unknown function (DUF454)
BVIR_RS07330	COG1200	Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y-DNA)
BVIR_RS07340	COG2938	An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH
BVIR_RS07345	COG1197	Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site
BVIR_RS07350	COG2095	MarC family integral membrane protein
BVIR_RS07355	COG0188	A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner
BVIR_RS07365	COG0669	Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate
BVIR_RS07385	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVIR_RS07390	COG1121	(ABC) transporter
BVIR_RS07395	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVIR_RS07400	COG1108	ABC-type Mn2 Zn2 transport systems permease components
BVIR_RS07405	COG0463	Glycosyl transferase, family 2
BVIR_RS07420	COG0626	cystathionine gamma-synthase activity
BVIR_RS07425	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVIR_RS07430	COG4597	amino acid ABC transporter
BVIR_RS07435	COG0765	amino acid transport
BVIR_RS07440	COG1126	abc transporter atp-binding protein
BVIR_RS07450	COG1038	Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second
BVIR_RS07455	COG2897	thiosulfate sulfurtransferase activity
BVIR_RS07470	COG2197	response regulator
BVIR_RS07490	COG0525	valine-tRNA ligase activity
BVIR_RS07495	COG2094	Belongs to the DNA glycosylase MPG family
BVIR_RS07500	COG0790	COG0790 FOG TPR repeat, SEL1 subfamily
BVIR_RS07505	COG0708	Exodeoxyribonuclease III
BVIR_RS07515	COG0232	Belongs to the dGTPase family. Type 2 subfamily
BVIR_RS07520	COG0018	arginyl-trna synthetase
BVIR_RS07530	COG1472	Belongs to the glycosyl hydrolase 3 family
BVIR_RS07535	COG1354	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves
BVIR_RS07540	COG1386	Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves
BVIR_RS07545	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVIR_RS07550	COG1826	Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes
BVIR_RS07555	COG0805	protein transport
BVIR_RS07560	COG0172	Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec)
BVIR_RS07565	COG0496	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates
BVIR_RS07570	COG2518	Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and or degradation of damaged proteins
BVIR_RS07590	COG1862	Preprotein translocase
BVIR_RS07595	COG0342	Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA
BVIR_RS07620	COG1206	Catalyzes the folate-dependent formation of 5-methyl- uridine at position 54 (M-5-U54) in all tRNAs
BVIR_RS07650	COG0557	exoribonuclease II activity
BVIR_RS07655	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS07665	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BVIR_RS07680	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS07685	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS07695	COG1464	Belongs to the NlpA lipoprotein family
BVIR_RS07700	COG0277	FAD linked oxidase domain protein
BVIR_RS07715	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVIR_RS07715	COG1116	anion transmembrane transporter activity
BVIR_RS07730	COG2057	Acyl CoA acetate 3-ketoacid CoA transferase beta subunit
BVIR_RS07735	COG0389	Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII
BVIR_RS07745	COG0784	Response regulator, receiver
BVIR_RS07755	COG0267	Belongs to the bacterial ribosomal protein bL33 family
BVIR_RS07760	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVIR_RS07765	COG3038	cytochrome b561
BVIR_RS07770	COG0303	'Molybdopterin
BVIR_RS07775	COG0315	cyclic pyranopterin monophosphate synthase activity
BVIR_RS07780	COG0134	indole-3-glycerol-phosphate synthase activity
BVIR_RS07785	COG0547	Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'-phosphoribosyl)-anthranilate (PRA)
BVIR_RS07795	COG0737	Belongs to the 5'-nucleotidase family
BVIR_RS07800	COG0147	Part of a heterotetrameric complex that catalyzes the two-step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine- binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate and high concentrations of ammonia
BVIR_RS07805	COG0760	Chaperone involved in the correct folding and assembly of outer membrane proteins. Recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act in both early periplasmic and late outer membrane-associated steps of protein maturation
BVIR_RS07810	COG0149	triose-phosphate isomerase activity
BVIR_RS07820	COG0504	CTP synthase activity
BVIR_RS07830	COG2824	Alkylphosphonate utilization operon protein PhnA
BVIR_RS07850	COG0697	spore germination
BVIR_RS07890	COG2128	Antioxidant protein with alkyl hydroperoxidase activity. Required for the reduction of the AhpC active site cysteine residues and for the regeneration of the AhpC enzyme activity
BVIR_RS07895	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BVIR_RS07900	COG1468	defense response to virus
BVIR_RS07900	COG1518	maintenance of DNA repeat elements
BVIR_RS07930	COG1686	Belongs to the peptidase S11 family
BVIR_RS07935	COG0125	Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis
BVIR_RS07940	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVIR_RS07950	COG0084	hydrolase, TatD family'
BVIR_RS07970	COG0753	catalase activity
BVIR_RS07975	COG3685	Protein conserved in bacteria
BVIR_RS07980	COG3956	TIGRFAM MazG family protein
BVIR_RS07995	COG0326	Molecular chaperone. Has ATPase activity
BVIR_RS08000	COG1278	Cold shock
BVIR_RS08030	COG0154	amidase activity
BVIR_RS08035	COG0721	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVIR_RS08040	COG2220	Zn-dependent hydrolases of the beta-lactamase fold
BVIR_RS08045	COG0816	Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA
BVIR_RS08055	COG0540	Belongs to the ATCase OTCase family
BVIR_RS08060	COG0044	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides
BVIR_RS08065	COG0344	acyl-phosphate glycerol-3-phosphate acyltransferase activity
BVIR_RS08070	COG0758	DNA mediated transformation
BVIR_RS08075	COG0550	Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone
BVIR_RS08075	COG1754	DNA topoisomerase type I activity
BVIR_RS08090	COG3237	CsbD-like
BVIR_RS08125	COG0640	Transcriptional regulator
BVIR_RS08155	COG1960	acyl-CoA dehydrogenase activity
BVIR_RS08175	COG0183	Belongs to the thiolase family
BVIR_RS08180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVIR_RS08180	COG0318	PFAM AMP-dependent synthetase and ligase
BVIR_RS08180	COG0300	oxidoreductase activity
BVIR_RS08180	COG3321	synthase
BVIR_RS08180	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS08185	COG1024	Enoyl-CoA hydratase
BVIR_RS08200	COG2021	Transfers an acetyl group from acetyl-CoA to L- homoserine, forming acetyl-L-homoserine
BVIR_RS08210	COG0346	lactoylglutathione lyase activity
BVIR_RS08215	COG0846	NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form
BVIR_RS08220	COG1278	Cold shock
BVIR_RS08250	COG0553	Transcription regulator that activates transcription by stimulating RNA polymerase (RNAP) recycling in case of stress conditions such as supercoiled DNA or high salt concentrations. Probably acts by releasing the RNAP, when it is trapped or immobilized on tightly supercoiled DNA. Does not activate transcription on linear DNA. Probably not involved in DNA repair
BVIR_RS08255	COG2202	Pas domain
BVIR_RS08255	COG3920	Histidine kinase
BVIR_RS08260	COG0629	single-stranded DNA binding
BVIR_RS08265	COG0178	The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 uvrA and 2 uvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by uvrB, the uvrA molecules dissociate
BVIR_RS08270	COG0625	glutathione transferase activity
BVIR_RS08280	COG3685	Protein conserved in bacteria
BVIR_RS08285	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVIR_RS08285	COG1648	precorrin-2 dehydrogenase activity
BVIR_RS08290	COG1797	cobyrinic acid a,c-diamide synthase activity
BVIR_RS08320	COG1807	4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family
BVIR_RS08470	COG5433	transposase activity
BVIR_RS08510	COG4147	Belongs to the sodium solute symporter (SSF) (TC 2.A.21) family
BVIR_RS08515	COG3162	membrane
BVIR_RS08525	COG1053	succinate dehydrogenase
BVIR_RS08530	COG0064	Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp- tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln)
BVIR_RS08535	COG0608	single-stranded DNA 5'-3' exodeoxyribonuclease activity
BVIR_RS08540	COG1494	fructose-1,6-bisphosphatase
BVIR_RS08550	COG0436	Aminotransferase
BVIR_RS08560	COG3243	poly(R)-hydroxyalkanoic acid synthase
BVIR_RS08565	COG4651	solute:proton antiporter activity
BVIR_RS08565	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVIR_RS08570	COG0002	Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde
BVIR_RS08575	COG0435	Glutathione S-transferase
BVIR_RS08590	COG0318	PFAM AMP-dependent synthetase and ligase
BVIR_RS08595	COG0010	Belongs to the arginase family
BVIR_RS08605	COG0187	DNA topoisomerase II activity
BVIR_RS08620	COG1064	alcohol dehydrogenase
BVIR_RS08625	COG4221	oxidoreductase activity
BVIR_RS08635	COG0441	Catalyzes the attachment of threonine to tRNA(Thr) in a two-step reaction L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr)
BVIR_RS08640	COG0759	Could be involved in insertion of integral membrane proteins into the membrane
BVIR_RS08650	COG0302	gtp cyclohydrolase
BVIR_RS08655	COG0139	Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP
BVIR_RS08665	COG4106	trans-aconitate 2-methyltransferase activity
BVIR_RS08670	COG5000	phosphorelay sensor kinase activity
BVIR_RS08705	COG0370	Transporter of a GTP-driven Fe(2 ) uptake system
BVIR_RS08705	COG1918	ferrous iron import across plasma membrane
BVIR_RS08710	COG0621	Catalyzes the methylthiolation of N6- (dimethylallyl)adenosine (i(6)A), leading to the formation of 2- methylthio-N6-(dimethylallyl)adenosine (ms(2)i(6)A) at position 37 in tRNAs that read codons beginning with uridine
BVIR_RS08720	COG0861	Integral membrane protein TerC family
BVIR_RS08725	COG1183	phosphatidylcholine synthase activity
BVIR_RS08740	COG0654	COG0654 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases
BVIR_RS08750	COG2301	Belongs to the HpcH HpaI aldolase family
BVIR_RS08760	COG1272	protein, Hemolysin III
BVIR_RS08770	COG2099	Precorrin-6x reductase
BVIR_RS08790	COG1492	cobalamin metabolic process
BVIR_RS08795	COG1396	sequence-specific DNA binding
BVIR_RS08805	COG4208	sulfate ABC transporter
BVIR_RS08815	COG1613	Sulfate ABC transporter periplasmic sulfate-binding protein
BVIR_RS08820	COG1464	Belongs to the NlpA lipoprotein family
BVIR_RS08825	COG1773	rubredoxin
BVIR_RS08855	COG0745	RESPONSE REGULATOR receiver
BVIR_RS08860	COG2205	protein histidine kinase activity
BVIR_RS08865	COG2156	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit acts as a catalytic chaperone that increases the ATP- binding affinity of the ATP-hydrolyzing subunit KdpB by the formation of a transient KdpB KdpC ATP ternary complex
BVIR_RS08870	COG2216	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit is responsible for energy coupling to the transport system
BVIR_RS08875	COG2060	Part of the high-affinity ATP-driven potassium transport (or Kdp) system, which catalyzes the hydrolysis of ATP coupled with the electrogenic transport of potassium into the cytoplasm. This subunit binds and transports the potassium across the cytoplasmic membrane
BVIR_RS08895	COG1278	Cold shock
BVIR_RS08910	COG1132	(ABC) transporter
BVIR_RS08920	COG4771	TonB-dependent receptor
BVIR_RS08950	COG0789	Transcriptional regulator
BVIR_RS08965	COG0640	Transcriptional regulator
BVIR_RS08975	COG1393	Belongs to the ArsC family
BVIR_RS08980	COG0798	PFAM Bile acid sodium symporter
BVIR_RS09005	COG5433	transposase activity
BVIR_RS09060	COG0811	peptide transport
BVIR_RS09065	COG2831	hemolysin activation secretion protein
BVIR_RS09130	COG5433	transposase activity
BVIR_RS09155	COG1396	sequence-specific DNA binding
BVIR_RS09160	COG2217	Heavy metal translocating P-type atpase
BVIR_RS09165	COG1121	(ABC) transporter
BVIR_RS09175	COG0803	Belongs to the bacterial solute-binding protein 9 family
BVIR_RS09180	COG0523	cobalamin synthesis protein
BVIR_RS09190	COG1268	BioY protein
BVIR_RS09200	COG1253	flavin adenine dinucleotide binding
BVIR_RS09210	COG0546	phosphoglycolate phosphatase activity
BVIR_RS09215	COG0154	amidase activity
BVIR_RS09220	COG0598	Magnesium transport protein CorA
BVIR_RS09230	COG1376	ErfK ybiS ycfS ynhG family protein
BVIR_RS09235	COG1408	metallophosphoesterase
BVIR_RS09240	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVIR_RS09255	COG0123	including yeast histone deacetylase and acetoin utilization protein
BVIR_RS09280	COG2262	GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis
BVIR_RS09285	COG1923	regulation of RNA biosynthetic process
BVIR_RS09295	COG2204	response regulator
BVIR_RS09300	COG5000	phosphorelay sensor kinase activity
BVIR_RS09310	COG2204	response regulator
BVIR_RS09320	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVIR_RS09325	COG1211	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity
BVIR_RS09325	COG0245	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase activity
BVIR_RS09330	COG1546	Belongs to the CinA family
BVIR_RS09335	COG2867	negative regulation of translational initiation
BVIR_RS09340	COG0320	Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives
BVIR_RS09345	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVIR_RS09350	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVIR_RS09355	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVIR_RS09355	COG0022	dehydrogenase e1 component
BVIR_RS09360	COG1071	oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor
BVIR_RS09375	COG0780	Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1)
BVIR_RS09380	COG0352	thiamine-phosphate diphosphorylase activity
BVIR_RS09385	COG2022	thiamine diphosphate biosynthetic process
BVIR_RS09395	COG2814	Major facilitator Superfamily
BVIR_RS09400	COG2877	3-deoxy-8-phosphooctulonate synthase activity
BVIR_RS09415	COG0343	queuine tRNA-ribosyltransferase activity
BVIR_RS09420	COG0809	Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA)
BVIR_RS09465	COG0488	(ABC) transporter
BVIR_RS09480	COG1052	Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family
BVIR_RS09485	COG1722	exodeoxyribonuclease VII activity
BVIR_RS09490	COG1154	Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP)
BVIR_RS09500	COG1189	Ribosomal RNA methyltransferase RrmJ FtsJ
BVIR_RS09505	COG2265	Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family
BVIR_RS09510	COG0807	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVIR_RS09510	COG0108	Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate
BVIR_RS09515	COG0082	Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system
BVIR_RS09525	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BVIR_RS09530	COG0484	heat shock protein binding
BVIR_RS09540	COG0259	pyridoxamine-phosphate oxidase activity
BVIR_RS09545	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS09560	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS09565	COG2089	acid synthase
BVIR_RS09575	COG3959	Transketolase, thiamine diphosphate binding domain
BVIR_RS09580	COG1083	cytidylyl-transferase
BVIR_RS09645	COG0277	FAD linked oxidase domain protein
BVIR_RS09655	COG1947	Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol
BVIR_RS09690	COG1492	cobalamin metabolic process
BVIR_RS09715	COG1080	General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr)
BVIR_RS09715	COG0574	Belongs to the PEP-utilizing enzyme family
BVIR_RS09730	COG0752	glycyl-tRNA synthetase alpha subunit
BVIR_RS09735	COG2835	tetraacyldisaccharide 4'-kinase activity
BVIR_RS09745	COG3118	belongs to the thioredoxin family
BVIR_RS09765	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS09770	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVIR_RS09790	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS09800	COG0477	Major facilitator Superfamily
BVIR_RS09805	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVIR_RS09810	COG1126	abc transporter atp-binding protein
BVIR_RS09815	COG0765	amino acid transport
BVIR_RS09820	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVIR_RS09830	COG0765	amino acid transport
BVIR_RS09835	COG0765	amino acid transport
BVIR_RS09875	COG0559	Belongs to the binding-protein-dependent transport system permease family
BVIR_RS09895	COG1464	Belongs to the NlpA lipoprotein family
BVIR_RS09900	COG0277	FAD linked oxidase domain protein
BVIR_RS09905	COG1167	Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain MocR family and their eukaryotic orthologs
BVIR_RS09910	COG4172	Belongs to the ABC transporter superfamily
BVIR_RS09960	COG0031	Belongs to the cysteine synthase cystathionine beta- synthase family
BVIR_RS09965	COG1522	sequence-specific DNA binding
BVIR_RS09985	COG0175	sulfate reduction
BVIR_RS09990	COG0155	Belongs to the nitrite and sulfite reductase 4Fe-4S domain family
BVIR_RS10000	COG0007	Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD- dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme
BVIR_RS10000	COG1648	precorrin-2 dehydrogenase activity
BVIR_RS10005	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BVIR_RS10030	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVIR_RS10075	COG1924	4 iron, 4 sulfur cluster binding
BVIR_RS10085	COG1959	2 iron, 2 sulfur cluster binding
BVIR_RS10090	COG0715	COG0715 ABC-type nitrate sulfonate bicarbonate transport systems periplasmic components
BVIR_RS10090	COG1116	anion transmembrane transporter activity
BVIR_RS10120	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVIR_RS10125	COG0520	Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine
BVIR_RS10135	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BVIR_RS10140	COG1468	defense response to virus
BVIR_RS10140	COG1518	maintenance of DNA repeat elements
BVIR_RS10200	COG0587	DNA-directed DNA polymerase activity
BVIR_RS10210	COG1971	Probably functions as a manganese efflux pump
BVIR_RS10230	COG2513	Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate
BVIR_RS10260	COG1607	acyl-coa hydrolase
BVIR_RS10265	COG0620	Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation
BVIR_RS10295	COG0310	cobalt ion transport
BVIR_RS10310	COG1522	sequence-specific DNA binding
BVIR_RS10315	COG1804	L-carnitine dehydratase bile acid-inducible protein F
BVIR_RS10330	COG4191	Histidine kinase
BVIR_RS10365	COG0446	pyridine nucleotide-disulphide oxidoreductase
BVIR_RS10370	COG0640	Transcriptional regulator
BVIR_RS10395	COG2230	cyclopropane-fatty-acyl-phospholipid synthase
BVIR_RS10400	COG2211	Major facilitator Superfamily
BVIR_RS10405	COG4221	oxidoreductase activity
BVIR_RS10410	COG3806	Anti-sigma factor
BVIR_RS10420	COG1233	COG1233 Phytoene dehydrogenase and related
BVIR_RS10430	COG0716	FMN binding
BVIR_RS10445	COG0615	ADP-L-glycero-beta-D-manno-heptose biosynthetic process
BVIR_RS10445	COG2870	Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno- heptose
BVIR_RS10450	COG0241	D,D-heptose 1,7-bisphosphate phosphatase
BVIR_RS10455	COG2942	2-epimerase
BVIR_RS10465	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS10475	COG1960	acyl-CoA dehydrogenase activity
BVIR_RS10480	COG1024	Enoyl-CoA hydratase
BVIR_RS10480	COG1250	3-hydroxyacyl-CoA dehydrogenase
BVIR_RS10485	COG0183	Belongs to the thiolase family
BVIR_RS10495	COG0318	PFAM AMP-dependent synthetase and ligase
BVIR_RS10520	COG1392	Phosphate transport regulator
BVIR_RS10525	COG0306	phosphate transporter
BVIR_RS10535	COG0834	ABC-type amino acid transport signal transduction systems periplasmic component domain
BVIR_RS10540	COG1376	ErfK ybiS ycfS ynhG family protein
BVIR_RS10550	COG0667	Aldo Keto reductase
BVIR_RS10575	COG0776	regulation of translation
BVIR_RS10580	COG0332	Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP. Catalyzes the first condensation reaction which initiates fatty acid synthesis and may therefore play a role in governing the total rate of fatty acid production. Possesses both acetoacetyl-ACP synthase and acetyl transacylase activities. Its substrate specificity determines the biosynthesis of branched- chain and or straight-chain of fatty acids
BVIR_RS10585	COG0416	fatty acid biosynthetic process
BVIR_RS10610	COG3808	pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for
BVIR_RS10615	COG0611	Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1
BVIR_RS10620	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVIR_RS10625	COG0054	6,7-dimethyl-8-ribityllumazine synthase activity
BVIR_RS10635	COG1985	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVIR_RS10635	COG0117	Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate
BVIR_RS10640	COG1327	Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR- boxes
BVIR_RS10645	COG0112	Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism
BVIR_RS10650	COG2227	3-demethylubiquinone-9 3-O-methyltransferase activity
BVIR_RS10655	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS10660	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVIR_RS10665	COG2935	proteasome-mediated ubiquitin-dependent protein catabolic process
BVIR_RS10680	COG1183	phosphatidylcholine synthase activity
BVIR_RS10690	COG5265	(ABC) transporter
BVIR_RS10695	COG0688	phosphatidylethanolamine metabolic process
BVIR_RS10715	COG0103	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
BVIR_RS10720	COG0102	This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly
BVIR_RS10740	COG1024	Enoyl-CoA hydratase
BVIR_RS10745	COG1832	CoA-binding protein
BVIR_RS10795	COG1518	maintenance of DNA repeat elements
BVIR_RS10800	COG1343	CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette
BVIR_RS10815	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVIR_RS10825	COG1120	ATPase activity
BVIR_RS10835	COG1131	(ABC) transporter
BVIR_RS10845	COG1309	transcriptional regulator
BVIR_RS10860	COG1207	Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain
BVIR_RS10865	COG1975	Xanthine and CO dehydrogenases maturation factor, XdhC CoxF family
BVIR_RS10865	COG3608	succinylglutamate desuccinylase aspartoacylase
BVIR_RS10895	COG1853	conserved protein domain typically associated with flavoprotein oxygenases, DIM6 NTAB family
BVIR_RS10930	COG0785	Cytochrome C biogenesis protein
BVIR_RS10935	COG2133	pyrroloquinoline quinone binding
BVIR_RS10940	COG3191	aminopeptidase activity
BVIR_RS10950	COG1540	5-oxoprolinase (ATP-hydrolyzing) activity
BVIR_RS10955	COG2049	5-oxoprolinase (ATP-hydrolyzing) activity
BVIR_RS10960	COG1984	allophanate hydrolase subunit 2
BVIR_RS10975	COG0691	Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene
BVIR_RS10980	COG0329	Catalyzes the condensation of (S)-aspartate-beta- semialdehyde (S)-ASA and pyruvate to 4-hydroxy- tetrahydrodipicolinate (HTPA)
BVIR_RS10985	COG0741	lytic transglycosylase activity
BVIR_RS10990	COG2086	electron transfer activity
BVIR_RS10995	COG2025	fatty acid beta-oxidation using acyl-CoA dehydrogenase
BVIR_RS11000	COG0644	oxidoreductase
BVIR_RS11005	COG2440	electron transfer flavoprotein-ubiquinone oxidoreductase
BVIR_RS11020	COG1348	The key enzymatic reactions in nitrogen fixation are catalyzed by the nitrogenase complex which has 2 components the iron protein and the molybdenum-iron protein
BVIR_RS11025	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS11030	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS11035	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS11040	COG2710	Component of the dark-operative protochlorophyllide reductase (DPOR) that uses Mg-ATP and reduced ferredoxin to reduce ring D of protochlorophyllide (Pchlide) to form chlorophyllide a (Chlide). This reaction is light-independent. The NB-protein
BVIR_RS11045	COG1433	Dinitrogenase iron-molybdenum cofactor
BVIR_RS11055	COG3383	formate dehydrogenase (NAD+) activity
BVIR_RS11095	COG2371	Involved in urease metallocenter assembly. Binds nickel. Probably functions as a nickel donor during metallocenter assembly
BVIR_RS11110	COG5554	nitrogen fixation
BVIR_RS11115	COG5554	nitrogen fixation
BVIR_RS11125	COG1145	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVIR_RS11130	COG0535	radical SAM domain protein
BVIR_RS11135	COG3604	Transcriptional regulator
BVIR_RS11140	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS11145	COG1146	Ferredoxins are iron-sulfur proteins that transfer electrons in a wide variety of metabolic reactions
BVIR_RS11145	COG0674	pyruvate-flavodoxin oxidoreductase activity
BVIR_RS11145	COG1014	Oxidoreductase required for the transfer of electrons from pyruvate to flavodoxin
BVIR_RS11145	COG1013	pyruvate-flavodoxin oxidoreductase activity
BVIR_RS11150	COG0493	'glutamate synthase
BVIR_RS11150	COG1142	4fe-4S ferredoxin, iron-sulfur binding domain protein
BVIR_RS11160	COG0747	negative chemotaxis
BVIR_RS11165	COG1473	amidohydrolase
BVIR_RS11175	COG1118	Part of the ABC transporter complex CysAWTP involved in sulfate thiosulfate import. Responsible for energy coupling to the transport system
BVIR_RS11190	COG0488	(ABC) transporter
BVIR_RS11205	COG5001	Diguanylate cyclase
BVIR_RS11210	COG0797	Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides
BVIR_RS11245	COG0730	response to heat
BVIR_RS11250	COG0042	Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines
BVIR_RS11260	COG0628	permease
BVIR_RS11275	COG1883	Na -transporting methylmalonyl-CoA oxaloacetate decarboxylase, beta subunit
BVIR_RS11295	COG1414	Transcriptional regulator
BVIR_RS11305	COG0053	Belongs to the cation diffusion facilitator (CDF) transporter (TC 2.A.4) family
BVIR_RS11315	COG0308	aminopeptidase N
BVIR_RS11320	COG2202	Pas domain
BVIR_RS11320	COG2205	protein histidine kinase activity
BVIR_RS11325	COG1391	[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase
BVIR_RS11330	COG2205	protein histidine kinase activity
BVIR_RS11340	COG0265	Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain
BVIR_RS11345	COG3088	subunit of a heme lyase
BVIR_RS11350	COG1138	Cytochrome C-type biogenesis protein
BVIR_RS11355	COG2332	Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH
BVIR_RS11360	COG4235	cytochrome complex assembly
BVIR_RS11485	COG0641	radical SAM
BVIR_RS11495	COG4695	Portal protein
BVIR_RS11510	COG2983	Belongs to the UPF0260 family
BVIR_RS11530	COG2166	iron-sulfur cluster assembly
BVIR_RS11540	COG2205	protein histidine kinase activity
BVIR_RS11575	COG5009	serine-type D-Ala-D-Ala carboxypeptidase activity
BVIR_RS11600	COG0605	Destroys radicals which are normally produced within the cells and which are toxic to biological systems
BVIR_RS11615	COG0229	Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine
BVIR_RS11620	COG4957	zinc ion binding
BVIR_RS11660	COG1999	signal sequence binding
BVIR_RS11665	COG5001	Diguanylate cyclase
BVIR_RS11665	COG3300	MHYT domain
BVIR_RS11680	COG0433	COG0433 Predicted ATPase
BVIR_RS11705	COG2226	methyltransferase
BVIR_RS11730	COG0382	Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3- octaprenyl-4-hydroxybenzoate
BVIR_RS11730	COG0546	phosphoglycolate phosphatase activity
BVIR_RS11740	COG5433	transposase activity
BVIR_RS11745	COG1974	Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair
BVIR_RS11755	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVIR_RS11760	COG0008	Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu)
BVIR_RS11765	COG0372	Belongs to the citrate synthase family
BVIR_RS11770	COG0763	Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVIR_RS11775	COG3494	Protein of unknown function (DUF1009)
BVIR_RS11780	COG1043	involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVIR_RS11785	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVIR_RS11790	COG1044	Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3-hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell
BVIR_RS11795	COG4775	Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane
BVIR_RS11800	COG0750	zinc metalloprotease
BVIR_RS11805	COG0743	1-deoxy-D-xylulose-5-phosphate reductoisomerase activity
BVIR_RS11815	COG0020	Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids
BVIR_RS11820	COG0233	cytoplasmic translational termination
BVIR_RS11825	COG0528	UMP kinase activity
BVIR_RS11830	COG0264	Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome
BVIR_RS11835	COG0052	Belongs to the universal ribosomal protein uS2 family
BVIR_RS11870	COG3842	ATPase activity
BVIR_RS11880	COG1840	ABC-type Fe3 transport system, periplasmic component
BVIR_RS11895	COG0745	RESPONSE REGULATOR receiver
BVIR_RS11900	COG1846	Transcriptional regulator
BVIR_RS11915	COG0314	molybdopterin synthase activity
BVIR_RS11925	COG0558	Belongs to the CDP-alcohol phosphatidyltransferase class-I family
BVIR_RS11930	COG0322	excinuclease ABC activity
BVIR_RS11945	COG3706	GGDEF domain
BVIR_RS11970	COG2801	Transposase and inactivated derivatives
BVIR_RS12000	COG0682	Transfers the N-acyl diglyceride group on what will become the N-terminal cysteine of membrane lipoproteins
BVIR_RS12010	COG1496	oxidoreductase activity
BVIR_RS12020	COG0462	Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P)
BVIR_RS12025	COG1825	This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance
BVIR_RS12030	COG0193	aminoacyl-tRNA hydrolase activity
BVIR_RS12035	COG0012	GTP binding
BVIR_RS12040	COG2030	dehydratase
BVIR_RS12050	COG0503	Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis
BVIR_RS12055	COG0005	The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate
BVIR_RS12075	COG0219	Methylates the ribose at the nucleotide 34 wobble position in the two leucyl isoacceptors tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). Catalyzes the methyl transfer from S- adenosyl-L-methionine to the 2'-OH of the wobble nucleotide
BVIR_RS12080	COG0408	coproporphyrinogen oxidase activity
BVIR_RS12095	COG0617	tRNA 3'-terminal CCA addition
BVIR_RS12115	COG0714	Associated with various cellular activities
BVIR_RS12185	COG0366	Alpha amylase catalytic
BVIR_RS12190	COG0296	Catalyzes the formation of the alpha-1,6-glucosidic linkages in glycogen by scission of a 1,4-alpha-linked oligosaccharide from growing alpha-1,4-glucan chains and the subsequent attachment of the oligosaccharide to the alpha-1,6 position
BVIR_RS12210	COG2183	response to ionizing radiation
BVIR_RS12220	COG1376	ErfK ybiS ycfS ynhG family protein
BVIR_RS12275	COG0848	biopolymer transport protein
BVIR_RS12285	COG2204	response regulator
BVIR_RS12335	COG1773	rubredoxin
BVIR_RS12355	COG1969	Ni Fe-hydrogenase, b-type cytochrome subunit
BVIR_RS12360	COG0374	Belongs to the NiFe NiFeSe hydrogenase large subunit family
BVIR_RS12365	COG1740	oxidoreductase activity, acting on hydrogen as donor, iron-sulfur protein as acceptor
BVIR_RS12390	COG3842	ATPase activity
BVIR_RS12450	COG2271	Major facilitator Superfamily
BVIR_RS12455	COG0483	inositol monophosphate 1-phosphatase activity
BVIR_RS12460	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BVIR_RS12470	COG0071	Belongs to the small heat shock protein (HSP20) family
BVIR_RS12480	COG0067	glutamate synthase
BVIR_RS12480	COG0069	glutamate synthase activity
BVIR_RS12480	COG0070	glutamate synthase
BVIR_RS12510	COG2951	lytic endotransglycosylase activity
BVIR_RS12520	COG1210	Utp--glucose-1-phosphate uridylyltransferase
BVIR_RS12525	COG0330	HflC and HflK could
BVIR_RS12550	COG2226	methyltransferase
BVIR_RS12555	COG0482	sulfurtransferase activity
BVIR_RS12570	COG1766	The M ring may be actively involved in energy transduction
BVIR_RS12575	COG1536	FliG is one of three proteins (FliG, FliN, FliM) that forms the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVIR_RS12585	COG1886	FliN is one of three proteins (FliG, FliN, FliM) that form the rotor-mounted switch complex (C ring), located at the base of the basal body. This complex interacts with the CheY and CheZ chemotaxis proteins, in addition to contacting components of the motor that determine the direction of flagellar rotation
BVIR_RS12590	COG2204	response regulator
BVIR_RS12600	COG1298	Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin
BVIR_RS12625	COG4953	penicillin-binding protein 1C
BVIR_RS12630	COG2373	Large extracellular alpha-helical protein
BVIR_RS12635	COG1443	Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP)
BVIR_RS12645	COG1733	regulation of RNA biosynthetic process
BVIR_RS12655	COG0840	transmembrane signaling receptor activity
BVIR_RS12660	COG2030	dehydratase
BVIR_RS12680	COG0559	Belongs to the binding-protein-dependent transport system permease family
BVIR_RS12685	COG4214	carbohydrate transport
BVIR_RS12695	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BVIR_RS12700	COG1271	oxidase subunit
BVIR_RS12705	COG1294	oxidase, subunit
BVIR_RS12735	COG2824	Alkylphosphonate utilization operon protein PhnA
BVIR_RS12740	COG1598	PFAM Uncharacterised protein family UPF0150
BVIR_RS12750	COG0043	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
BVIR_RS12760	COG0826	peptidase U32
BVIR_RS12765	COG0826	peptidase U32
BVIR_RS12805	COG1703	isobutyryl-CoA mutase activity
BVIR_RS12810	COG0294	Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8-dihydropteroate (H2Pte), the immediate precursor of folate derivatives
BVIR_RS12820	COG0801	2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase
BVIR_RS12835	COG0828	Belongs to the bacterial ribosomal protein bS21 family
BVIR_RS12840	COG1249	Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family
BVIR_RS12855	COG0508	dehydrogenase complex catalyzes the overall conversion of
BVIR_RS12870	COG0045	succinate-CoA ligase (ADP-forming) activity
BVIR_RS12885	COG1485	Reduces the stability of FtsZ polymers in the presence of ATP
BVIR_RS12905	COG1053	succinate dehydrogenase
BVIR_RS12935	COG5433	transposase activity
BVIR_RS12950	COG2030	dehydratase
BVIR_RS12955	COG0556	nucleotide-excision repair
BVIR_RS12960	COG0142	geranyltranstransferase activity
BVIR_RS12965	COG0596	Alpha beta hydrolase
BVIR_RS13000	COG2189	Belongs to the N(4) N(6)-methyltransferase family
BVIR_RS13010	COG1194	a g-specific adenine glycosylase
BVIR_RS13025	COG1196	nuclear chromosome segregation
BVIR_RS13045	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BVIR_RS13050	COG0711	Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0)
BVIR_RS13055	COG1003	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVIR_RS13060	COG0403	The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor
BVIR_RS13065	COG0509	glycine decarboxylation via glycine cleavage system
BVIR_RS13070	COG0404	The glycine cleavage system catalyzes the degradation of glycine
BVIR_RS13080	COG0612	Peptidase, M16
BVIR_RS13085	COG0612	Peptidase, M16
BVIR_RS13095	COG2274	protein secretion by the type I secretion system
BVIR_RS13105	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS13130	COG0597	This protein specifically catalyzes the removal of signal peptides from prolipoproteins
BVIR_RS13145	COG0060	amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile)
BVIR_RS13150	COG0840	transmembrane signaling receptor activity
BVIR_RS13155	COG0196	riboflavin kinase activity
BVIR_RS13160	COG2030	dehydratase
BVIR_RS13165	COG0745	RESPONSE REGULATOR receiver
BVIR_RS13185	COG0463	Glycosyl transferase, family 2
BVIR_RS13195	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVIR_RS13195	COG1042	CoA-binding domain protein
BVIR_RS13195	COG0045	succinate-CoA ligase (ADP-forming) activity
BVIR_RS13200	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVIR_RS13220	COG4178	(ABC) transporter
BVIR_RS13225	COG0459	protein refolding
BVIR_RS13230	COG0234	Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter
BVIR_RS13245	COG0210	DNA helicase
BVIR_RS13255	COG5433	transposase activity
BVIR_RS13260	COG2264	protein methyltransferase activity
BVIR_RS13270	COG0277	FAD linked oxidase domain protein
BVIR_RS13290	COG0026	Catalyzes the ATP-dependent conversion of 5- aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5- carboxyaminoimidazole ribonucleotide (N5-CAIR)
BVIR_RS13300	COG5002	protein histidine kinase activity
BVIR_RS13300	COG3447	MASE1 domain protein
BVIR_RS13300	COG5001	Diguanylate cyclase
BVIR_RS13305	COG0328	RNA-DNA hybrid ribonuclease activity
BVIR_RS13310	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVIR_RS13315	COG0761	Catalyzes the conversion of 1-hydroxy-2-methyl-2-(E)- butenyl 4-diphosphate (HMBPP) into a mixture of isopentenyl diphosphate (IPP) and dimethylallyl diphosphate (DMAPP). Acts in the terminal step of the DOXP MEP pathway for isoprenoid precursor biosynthesis
BVIR_RS13320	COG0465	Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins
BVIR_RS13325	COG0037	tRNA processing
BVIR_RS13335	COG2885	chlorophyll binding
BVIR_RS13340	COG0841	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVIR_RS13345	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS13355	COG0524	Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5- phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway
BVIR_RS13370	COG0258	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVIR_RS13370	COG0749	In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity
BVIR_RS13380	COG1004	Belongs to the UDP-glucose GDP-mannose dehydrogenase family
BVIR_RS13385	COG1643	Atp-dependent helicase
BVIR_RS13390	COG0840	transmembrane signaling receptor activity
BVIR_RS13395	COG0840	transmembrane signaling receptor activity
BVIR_RS13410	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVIR_RS13435	COG4964	Belongs to the GSP D family
BVIR_RS13470	COG0260	Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides
BVIR_RS13490	COG1212	Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria
BVIR_RS13495	COG4166	transmembrane transport
BVIR_RS13500	COG4166	transmembrane transport
BVIR_RS13505	COG4174	ABC transporter (Permease)
BVIR_RS13510	COG4239	(ABC) transporter, permease
BVIR_RS13525	COG4172	Belongs to the ABC transporter superfamily
BVIR_RS13540	COG0583	DNA-binding transcription factor activity
BVIR_RS13565	COG0174	glutamine synthetase
BVIR_RS13570	COG3842	ATPase activity
BVIR_RS13580	COG1176	ABC-type spermidine putrescine transport system, permease component I
BVIR_RS13585	COG1177	transmembrane transport
BVIR_RS13590	COG0166	Belongs to the GPI family
BVIR_RS13605	COG2862	Uncharacterized protein family, UPF0114
BVIR_RS13620	COG0218	Necessary for normal cell division and for the maintenance of normal septation
BVIR_RS13625	COG0706	membrane insertase activity
BVIR_RS13635	COG0230	Belongs to the bacterial ribosomal protein bL34 family
BVIR_RS13645	COG0128	3-phosphoshikimate 1-carboxyvinyltransferase activity
BVIR_RS13650	COG0283	belongs to the cytidylate kinase family. Type 1 subfamily
BVIR_RS13655	COG0539	negative regulation of cytoplasmic translation
BVIR_RS13715	COG1309	transcriptional regulator
BVIR_RS13725	COG0280	phosphate acetyltransferase
BVIR_RS13725	COG0281	malic enzyme
BVIR_RS13730	COG0249	that it carries out the mismatch recognition step. This protein has a weak ATPase activity
BVIR_RS13740	COG2844	Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen
BVIR_RS13810	COG0318	PFAM AMP-dependent synthetase and ligase
BVIR_RS13810	COG3321	synthase
BVIR_RS13810	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS13810	COG0300	oxidoreductase activity
BVIR_RS13810	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVIR_RS13820	COG0367	asparagine synthase
BVIR_RS13825	COG1960	acyl-CoA dehydrogenase activity
BVIR_RS13860	COG1509	lysine 2,3-aminomutase activity
BVIR_RS13865	COG0161	adenosylmethionine-8-amino-7-oxononanoate transaminase activity
BVIR_RS13880	COG3609	addiction module antidote protein, CC2985 family
BVIR_RS13915	COG0477	Major facilitator Superfamily
BVIR_RS13940	COG5433	transposase activity
BVIR_RS13960	COG3387	PFAM Glycoside hydrolase 15-related
BVIR_RS13965	COG1877	trehalose-phosphatase activity
BVIR_RS13970	COG0380	Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose-6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor
BVIR_RS13975	COG4221	oxidoreductase activity
BVIR_RS13985	COG2217	Heavy metal translocating P-type atpase
BVIR_RS14005	COG2010	Cytochrome c
BVIR_RS14020	COG3278	Belongs to the heme-copper respiratory oxidase family
BVIR_RS14025	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVIR_RS14040	COG0745	RESPONSE REGULATOR receiver
BVIR_RS14045	COG2205	protein histidine kinase activity
BVIR_RS14055	COG3444	protein-N(PI)-phosphohistidine-sugar phosphotransferase activity
BVIR_RS14055	COG2893	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVIR_RS14060	COG1902	pentaerythritol trinitrate reductase activity
BVIR_RS14105	COG0823	Involved in the tonB-independent uptake of proteins
BVIR_RS14115	COG0848	biopolymer transport protein
BVIR_RS14145	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVIR_RS14165	COG0114	fumarate hydratase activity
BVIR_RS14185	COG0330	HflC and HflK could
BVIR_RS14200	COG1522	sequence-specific DNA binding
BVIR_RS14225	COG0432	Pfam Uncharacterised protein family UPF0047
BVIR_RS14245	COG0119	Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3-hydroxy-4-methylpentanoate (2-isopropylmalate)
BVIR_RS14250	COG5433	transposase activity
BVIR_RS14255	COG0588	phosphoglycerate mutase activity
BVIR_RS14260	COG0289	4-hydroxy-tetrahydrodipicolinate reductase
BVIR_RS14270	COG0284	orotidine-5'-phosphate decarboxylase activity
BVIR_RS14275	COG0030	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity
BVIR_RS14280	COG0484	heat shock protein binding
BVIR_RS14285	COG0443	Heat shock 70 kDa protein
BVIR_RS14305	COG0576	Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ
BVIR_RS14315	COG0689	Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates
BVIR_RS14320	COG0127	Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA RNA and avoiding chromosomal lesions
BVIR_RS14325	COG0635	Involved in the biosynthesis of porphyrin-containing compound
BVIR_RS14335	COG0313	Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA
BVIR_RS14340	COG0792	nuclease activity
BVIR_RS14345	COG0189	ligase activity
BVIR_RS14360	COG3850	Histidine kinase
BVIR_RS14360	COG3437	response regulator, receiver
BVIR_RS14360	COG2205	protein histidine kinase activity
BVIR_RS14360	COG4999	Histidine kinase
BVIR_RS14405	COG1053	succinate dehydrogenase
BVIR_RS14410	COG0479	Belongs to the succinate dehydrogenase fumarate reductase iron-sulfur protein family
BVIR_RS14425	COG1201	RNA secondary structure unwinding
BVIR_RS14435	COG2816	NAD+ diphosphatase activity
BVIR_RS14450	COG2812	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity
BVIR_RS14455	COG0718	Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection
BVIR_RS14460	COG0353	May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO
BVIR_RS14465	COG2223	nitrite transmembrane transporter activity
BVIR_RS14470	COG2814	Major facilitator Superfamily
BVIR_RS14480	COG0251	oxidation-reduction process
BVIR_RS14485	COG1509	lysine 2,3-aminomutase activity
BVIR_RS14490	COG2269	With EpmB is involved in the beta-lysylation step of the post-translational modification of translation elongation factor P (EF-P). Catalyzes the ATP-dependent activation of (R)-beta-lysine produced by EpmB, forming a lysyl-adenylate, from which the beta- lysyl moiety is then transferred to the epsilon-amino group of a conserved specific lysine residue in EF-P
BVIR_RS14495	COG0231	Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase
BVIR_RS14515	COG3852	Histidine kinase
BVIR_RS14520	COG3422	double-strand break repair
BVIR_RS14530	COG3770	Murein endopeptidase that cleaves the D-alanyl-meso-2,6- diamino-pimelyl amide bond that connects peptidoglycan strands. Likely plays a role in the removal of murein from the sacculus
BVIR_RS14545	COG0190	Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate
BVIR_RS14550	COG1872	DUF167
BVIR_RS14570	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS14580	COG3842	ATPase activity
BVIR_RS14585	COG1177	transmembrane transport
BVIR_RS14595	COG1349	DNA-binding transcription factor activity
BVIR_RS14605	COG2334	A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response
BVIR_RS14610	COG0160	Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family
BVIR_RS14615	COG0604	alcohol dehydrogenase
BVIR_RS14625	COG0379	Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate
BVIR_RS14630	COG0029	Catalyzes the oxidation of L-aspartate to iminoaspartate
BVIR_RS14640	COG0059	Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol- acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3- dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3- hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate
BVIR_RS14645	COG0440	acetolactate synthase activity
BVIR_RS14650	COG0028	Belongs to the TPP enzyme family
BVIR_RS14660	COG0324	Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A)
BVIR_RS14665	COG3830	Belongs to the UPF0237 family
BVIR_RS14665	COG0560	Phosphoserine phosphatase
BVIR_RS14670	COG0469	pyruvate kinase activity
BVIR_RS14685	COG0776	regulation of translation
BVIR_RS14690	COG0616	signal peptide processing
BVIR_RS14705	COG1215	transferase activity, transferring glycosyl groups
BVIR_RS14725	COG0673	inositol 2-dehydrogenase activity
BVIR_RS14730	COG1922	lipopolysaccharide N-acetylmannosaminouronosyltransferase activity
BVIR_RS14745	COG0175	sulfate reduction
BVIR_RS14760	COG0590	tRNA wobble adenosine to inosine editing
BVIR_RS14770	COG0742	ribosomal rna small subunit methyltransferase
BVIR_RS14775	COG0323	This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a molecular matchmaker , a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex
BVIR_RS14780	COG0111	D-isomer specific 2-hydroxyacid dehydrogenase
BVIR_RS14800	COG1109	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate
BVIR_RS14805	COG0365	Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA
BVIR_RS14815	COG2192	nodulation
BVIR_RS14825	COG0422	Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction
BVIR_RS14840	COG0207	Catalyzes the reductive methylation of 2'-deoxyuridine- 5'-monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by-product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis
BVIR_RS14855	COG0789	Transcriptional regulator
BVIR_RS14860	COG0242	peptide deformylase activity
BVIR_RS14865	COG1226	(belongs to the monovalent cation proton antiporter 2 (CPA2) transporter (TC 2.A.37) family)
BVIR_RS14865	COG0475	glutathione-regulated potassium exporter activity
BVIR_RS14870	COG0312	modulator of DNA gyrase
BVIR_RS14885	COG0612	Peptidase, M16
BVIR_RS14890	COG1670	COG1670 acetyltransferases, including N-acetylases of ribosomal proteins
BVIR_RS14900	COG0730	response to heat
BVIR_RS14910	COG1274	phosphoenolpyruvate carboxykinase (GTP) activity
BVIR_RS14930	COG2321	neutral zinc metallopeptidase
BVIR_RS14935	COG0164	Endonuclease that specifically degrades the RNA of RNA- DNA hybrids
BVIR_RS14955	COG0104	Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP
BVIR_RS14975	COG0167	dihydroorotate dehydrogenase activity
BVIR_RS14985	COG2226	methyltransferase
BVIR_RS14990	COG3300	MHYT domain
BVIR_RS14990	COG5001	Diguanylate cyclase
BVIR_RS15000	COG1185	polyribonucleotide nucleotidyltransferase activity
BVIR_RS15005	COG0184	Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome
BVIR_RS15010	COG0130	Responsible for synthesis of pseudouridine from uracil- 55 in the psi GC loop of transfer RNAs
BVIR_RS15015	COG0858	One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA
BVIR_RS15020	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BVIR_RS15020	COG0532	One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex
BVIR_RS15035	COG0779	Required for maturation of 30S ribosomal subunits
BVIR_RS15050	COG0072	phenylalanine-tRNA ligase activity
BVIR_RS15050	COG0073	Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation
BVIR_RS15055	COG2852	Protein conserved in bacteria
BVIR_RS15065	COG0016	Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily
BVIR_RS15070	COG0292	Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit
BVIR_RS15075	COG0291	Belongs to the bacterial ribosomal protein bL35 family
BVIR_RS15080	COG0290	IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins
BVIR_RS15095	COG2814	Major facilitator Superfamily
BVIR_RS15110	COG0223	Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus
BVIR_RS15115	COG1925	phosphoenolpyruvate-dependent sugar phosphotransferase system
BVIR_RS15120	COG0499	May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine
BVIR_RS15135	COG4607	ABC-type enterochelin transport system periplasmic component
BVIR_RS15140	COG4606	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVIR_RS15145	COG4605	iron ion homeostasis
BVIR_RS15150	COG4604	ABC transporter, ATP-binding protein
BVIR_RS15155	COG0477	Major facilitator Superfamily
BVIR_RS15160	COG0845	Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family
BVIR_RS15165	COG1136	(ABC) transporter
BVIR_RS15165	COG0577	efflux transmembrane transporter activity
BVIR_RS15170	COG3433	isochorismatase activity
BVIR_RS15170	COG1535	isochorismatase
BVIR_RS15180	COG1020	D-alanine [D-alanyl carrier protein] ligase activity
BVIR_RS15190	COG1021	2,3-dihydroxybenzoate-AMP ligase
BVIR_RS15195	COG1535	isochorismatase
BVIR_RS15195	COG3433	isochorismatase activity
BVIR_RS15200	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS15215	COG4774	siderophore transport
BVIR_RS15220	COG2382	esterase
BVIR_RS15230	COG4559	Part of the ABC transporter complex HmuTUV involved in hemin import. Responsible for energy coupling to the transport system
BVIR_RS15235	COG0609	Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily
BVIR_RS15245	COG2819	hydrolase of the alpha beta superfamily
BVIR_RS15250	COG4774	siderophore transport
BVIR_RS15265	COG0491	Thiolesterase that catalyzes the hydrolysis of S-D- lactoyl-glutathione to form glutathione and D-lactic acid
BVIR_RS15290	COG2244	polysaccharide biosynthetic process
BVIR_RS15320	COG0735	belongs to the Fur family
BVIR_RS15325	COG0764	3-hydroxyoctanoyl-[acyl-carrier-protein] dehydratase activity
BVIR_RS15335	COG0623	enoyl-[acyl-carrier-protein] reductase (NADH) activity
BVIR_RS15385	COG2308	Evidence 4 Homologs of previously reported genes of
BVIR_RS15385	COG2307	Protein conserved in bacteria
BVIR_RS15405	COG0439	Biotin carboxylase
BVIR_RS15420	COG1116	anion transmembrane transporter activity
BVIR_RS15425	COG0600	ABC-type nitrate sulfonate bicarbonate transport system permease component
BVIR_RS15440	COG0664	- Catabolite gene activator and regulatory subunit of cAMP-dependent protein
BVIR_RS15470	COG1024	Enoyl-CoA hydratase
BVIR_RS15475	COG0266	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
BVIR_RS15480	COG2226	methyltransferase
BVIR_RS15485	COG0661	Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis
BVIR_RS15500	COG0452	Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine
BVIR_RS15505	COG0756	dUTP diphosphatase activity
BVIR_RS15520	COG2205	protein histidine kinase activity
BVIR_RS15525	COG3178	'Phosphotransferase
BVIR_RS15530	COG1208	COG1208 Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis translation initiation factor 2B, gamma epsilon subunits eIF-2Bgamma eIF-2Bepsilon
BVIR_RS15540	COG1074	ATP-dependent DNA helicase activity
BVIR_RS15550	COG1896	Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates
BVIR_RS15565	COG4992	N2-acetyl-L-ornithine:2-oxoglutarate 5-aminotransferase activity
BVIR_RS15570	COG0078	Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline
BVIR_RS15580	COG0361	One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre- initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initation complex
BVIR_RS15585	COG0513	Belongs to the DEAD box helicase family
BVIR_RS15605	COG2240	Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP
BVIR_RS15625	COG1512	COG1512 Beta-propeller domains of methanol dehydrogenase type
BVIR_RS15630	COG1704	LemA family
BVIR_RS15640	COG1595	DNA-templated transcription, initiation
BVIR_RS15655	COG0495	leucyl-tRNA aminoacylation
BVIR_RS15685	COG5002	protein histidine kinase activity
BVIR_RS15695	COG0573	inorganic phosphate transmembrane transporter activity
BVIR_RS15705	COG1117	ATPase-coupled phosphate ion transmembrane transporter activity
BVIR_RS15710	COG0704	Plays a role in the regulation of phosphate uptake
BVIR_RS15715	COG0745	RESPONSE REGULATOR receiver
BVIR_RS15735	COG3696	Belongs to the resistance-nodulation-cell division (RND) (TC 2.A.6) family
BVIR_RS15740	COG1384	Belongs to the class-I aminoacyl-tRNA synthetase family
BVIR_RS15755	COG1999	signal sequence binding
BVIR_RS15780	COG0777	Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA
BVIR_RS15785	COG0159	tryptophan synthase activity
BVIR_RS15790	COG0133	tryptophan synthase activity
BVIR_RS15795	COG0135	phosphoribosylanthranilate isomerase activity
BVIR_RS15800	COG2255	four-way junction helicase activity
BVIR_RS15810	COG0824	Thioesterase
BVIR_RS15850	COG0182	Catalyzes the interconversion of methylthioribose-1- phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1- P)
BVIR_RS15855	COG0235	Class ii aldolase
BVIR_RS15865	COG4567	Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain
BVIR_RS15885	COG0052	Belongs to the universal ribosomal protein uS2 family
BVIR_RS15900	COG1600	Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr)
BVIR_RS15910	COG1072	(Pantothenic acid kinase))
BVIR_RS15915	COG0140	phosphoribosyl-ATP diphosphatase activity
BVIR_RS15920	COG0107	imidazoleglycerol-phosphate synthase activity
BVIR_RS15930	COG0118	IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR
BVIR_RS15940	COG0131	Imidazoleglycerol-phosphate dehydratase
BVIR_RS15945	COG5405	Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery
BVIR_RS15950	COG1220	this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis
BVIR_RS15955	COG4108	Increases the formation of ribosomal termination complexes and stimulates activities of RF-1 and RF-2. It binds guanine nucleotides and has strong preference for UGA stop codons. It may interact directly with the ribosome. The stimulation of RF- 1 and RF-2 is significantly reduced by GTP and GDP, but not by GMP
BVIR_RS15965	COG2821	murein-degrading enzyme. may play a role in recycling of muropeptides during cell elongation and or cell division
BVIR_RS15975	COG1952	One of the proteins required for the normal export of preproteins out of the cell cytoplasm. It is a molecular chaperone that binds to a subset of precursor proteins, maintaining them in a translocation-competent state. It also specifically binds to its receptor SecA
BVIR_RS15980	COG0847	DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease
BVIR_RS15985	COG0237	dephospho-CoA kinase activity
BVIR_RS15990	COG0169	Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA)
BVIR_RS15995	COG0424	maF-like protein
BVIR_RS16000	COG1806	Bifunctional serine threonine kinase and phosphorylase involved in the regulation of the
BVIR_RS16005	COG0407	Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III
BVIR_RS16010	COG1981	membrane
BVIR_RS16015	COG1158	Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template
BVIR_RS16020	COG1331	Highly conserved protein containing a thioredoxin domain
BVIR_RS16025	COG0486	Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34
BVIR_RS16030	COG0445	tRNA wobble uridine modification
BVIR_RS16035	COG0357	Ribosomal RNA small subunit methyltransferase G
BVIR_RS16050	COG0604	alcohol dehydrogenase
BVIR_RS16050	COG1028	Short-chain dehydrogenase reductase Sdr
BVIR_RS16050	COG3321	synthase
BVIR_RS16065	COG0820	rRNA (adenine-C2-)-methyltransferase activity
BVIR_RS16070	COG0288	reversible hydration of carbon dioxide
BVIR_RS16075	COG0136	Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L- aspartyl-4-phosphate
BVIR_RS16090	COG0473	3-isopropylmalate dehydrogenase activity
BVIR_RS16095	COG2951	lytic endotransglycosylase activity
BVIR_RS16105	COG0745	RESPONSE REGULATOR receiver
BVIR_RS16115	COG0137	argininosuccinate synthase activity
BVIR_RS16135	COG0501	Belongs to the peptidase M48B family
BVIR_RS16140	COG1217	gtp-binding protein TYPA
BVIR_RS16145	COG1994	Peptidase M50
BVIR_RS16145	COG0517	IMP dehydrogenase activity
BVIR_RS16150	COG1247	-acetyltransferase
BVIR_RS16155	COG0221	Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions
BVIR_RS16165	COG0138	bifunctional purine biosynthesis protein purh
BVIR_RS16175	COG0781	Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons
BVIR_RS16175	COG0144	Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA